TWAS hub - SLCO1C1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1410	0.0330	5.3e-08	0.051	0.066	0.104	0.080	0.096	8.3e-07	1.9e-08	1.3e-12	4.9e-10	9.5e-12
2	ROSMAP	Brain Pre-frontal Cortex	0.0768	0.0253	2.0e-05	0.017	0.052	0.049	0.052	0.050	2.2e-03	2.5e-07	5.3e-07	2.6e-07	4.2e-07
3	TCGA	Brain Lower Grade Glioma	0.0278	0.0160	9.1e-03	-0.001	0.012	0.002	NA	0.003	5.2e-01	1.3e-02	1.7e-01	NA	1.4e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Peak expiratory flow (PEF)	6.9	16.1	19.0	-4.4	-4.1	-3.5
Worry too long after embarrassment	6.9	11.6	12.9	-3.5	-3.6	-3.1
Guilty feelings	6.0	9.1	14.1	-3.8	-2.2	-2.9
Eye problems/disorders: Diabetes related eye disease	5.2	5.7	6.9	2.3	2.6	2.2
Forced vital capacity (FVC)	4.9	18.9	28.9	-4.6	-5.4	-2.6
Forced expiratory volume in 1-second (FEV1)	4.8	16.1	23.0	-4.2	-4.8	-2.7
Smoking status: Previous	4.8	7.2	7.6	2.7	2.8	2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.8	10.2	13.7	-2.9	-3.0	-3.7
Forced vital capacity (FVC), Best measure	4.3	15.6	21.3	-3.9	-4.6	-3.2
Hearing difficulty/problems with background noise	4.2	6.6	9.4	-3.0	-1.3	-3.1
Forced expiratory volume in 1-second (FEV1), Best measure	4.2	13.5	17.3	-3.6	-4.2	-3.2
Frequency of tenseness / restlessness in last 2 weeks	4.0	6.2	9.1	-3.0	-0.8	-3.0
Migraine (self-reported)	3.9	4.9	7.0	2.6	1.5	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.8	4.5	7.0	1.9	1.7	2.6
Ever smoked	3.8	6.7	7.3	2.5	2.7	2.5
Past tobacco smoking	3.7	6.8	8.2	-2.6	-2.9	-2.4
Sensitivity / hurt feelings	3.6	6.1	9.4	-2.8	-1.0	-3.1
Ever had hysterectomy (womb removed)	3.6	4.0	4.4	2.1	2.1	1.8
Friendships satisfaction	3.6	4.5	6.5	-2.5	-1.7	-2.1
Ovarian Cancer	3.5	4.7	7.1	1.9	2.7	1.8
Mouth/teeth dental problems: Dentures	3.5	6.0	9.7	2.3	3.1	1.6
Medication: Gliclazide	3.5	4.0	5.1	2.1	2.3	1.6
Happiness	3.4	4.2	5.9	-2.4	-1.1	-2.4
Primary Biliary Cirrhosis	3.2	4.6	6.0	2.5	1.7	2.2
Falls in the last year	3.1	4.2	6.8	1.5	2.6	1.8
Medication for cholesterol, blood pressure or diabetes	3.1	5.1	5.5	-2.2	-2.2	-2.4
Lung FVC	3.0	15.0	18.4	-4.1	-4.3	-3.2
Medication: Aspirin	3.0	3.9	4.8	1.8	2.2	1.9
Intelligence (Savage-Jansen 2018)	2.9	9.0	13.2	-3.4	-3.6	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.9	3.5	5.7	1.7	2.4	1.3
Bipolar Disorder or Schizophrenia	2.7	6.5	9.1	3.0	2.0	2.5
Neuroticism score	2.7	5.6	7.9	-2.5	-1.7	-2.8
Worrier / anxious feelings	2.7	5.0	6.2	-2.5	-2.4	-1.8
Medication: Aspirin	2.7	3.6	4.7	1.6	2.2	1.8
Neuroticism (Nagel 2018)	2.6	6.2	10.6	-3.3	-1.4	-2.5
Alcohol intake versus 10 years previously	2.6	3.8	7.3	-1.5	-1.4	-2.7
Age started oral contraceptive pill	2.6	3.3	5.6	-2.4	-1.3	-1.6
Schizophrenia (2018)	2.5	5.2	7.0	2.6	1.9	2.2
Eye problems/disorders: None of the above	2.4	2.8	5.1	-1.1	-2.3	-1.4
Medication: Omeprazole	2.4	2.9	4.8	-1.9	-0.6	-2.2
Supplements: Zinc	2.3	2.5	4.1	-1.4	-1.2	-2.0
Bilateral oophorectomy (both ovaries removed)	2.3	2.7	3.6	1.6	1.4	1.9
Heel bone mineral density (BMD) T-score, automated (left)	2.3	5.3	5.8	-2.4	-2.1	-2.3
Qualifications: CSEs or equivalent	2.3	3.0	5.0	2.2	1.8	0.8
Qualifications: College or University degree	2.3	7.2	9.8	-3.1	-2.6	-2.2
Verbal and Numeric Reasoning (VNR)	2.2	5.4	8.5	-2.9	-2.6	-0.9
Schizophrenia (2014)	2.2	4.8	6.7	2.6	1.8	2.1
Breastfed as a baby	2.2	2.7	5.6	-1.4	-2.4	-0.7
Chest pain or discomfort	2.2	3.2	4.7	-1.8	-1.2	-2.2
Medication: Omeprazole (e.g. Zanprol)	2.2	2.7	3.7	-1.9	-1.3	-1.6
Alzheimer’s Disease (in father)	2.1	2.3	2.6	1.6	1.4	1.5
Alzheimer’s Disease (including proxy)	2.1	3.0	6.8	1.4	2.6	0.5
Comparative height size at age 10	2.1	11.6	17.6	-4.1	-4.2	-0.4
Height	2.0	39.0	58.3	-7.6	-7.5	-1.7
Hand grip strength (right)	1.9	5.2	7.7	-2.8	-1.6	-2.3
Worry (Nagel 2018)	1.8	3.9	6.3	-2.5	-1.8	-1.4
Smoking Status	1.8	4.3	7.1	2.1	2.7	1.2
Neuroticism	1.8	4.4	6.9	-2.6	-1.4	-2.0
Age at first live birth	1.8	3.2	4.0	-1.8	-2.0	-1.6
Age at last live birth	1.8	2.7	3.8	-2.0	-0.8	-1.9
Medication: Cholesterol lowering	1.7	2.6	2.9	1.6	1.7	1.6
Length of working week for main job	1.7	1.9	3.4	-0.8	-1.8	-1.3
Age at First Birth	1.6	2.4	3.2	-1.1	-1.7	-1.8
HDL Cholesterol	1.6	2.6	4.3	-2.1	-0.4	-1.8
Hand grip strength (left)	1.6	4.2	5.1	-2.3	-1.8	-2.0
Nervous feelings	1.6	3.0	4.3	-1.9	-1.0	-2.1
Ever depressed for a whole week	1.6	2.0	3.2	-1.7	-0.2	-1.8
Deep venous thrombosis (DVT) (self-reported)	1.6	2.0	3.1	1.2	1.8	1.2
Lupus	1.5	2.2	3.3	-1.6	-1.8	-0.8
Shortness of breath walking on level ground	1.5	1.8	2.9	1.4	0.7	1.7
Wears glasses or contact lenses	1.5	1.7	1.9	1.3	1.2	1.4
Cholesterol lowering medication	1.5	2.1	3.5	-1.9	-0.1	-1.7
Medication: Metformin	1.4	2.0	3.1	1.8	1.5	0.8
Medication: Ramipril	1.4	1.8	2.5	1.6	1.4	0.9
Standing height	1.4	13.4	21.3	-4.6	-4.4	-0.2
Pulse wave peak to peak time	1.4	1.6	1.7	-1.3	-1.2	-1.3
Depression (Nagel 2018)	1.3	2.0	4.4	-2.1	-0.3	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	2.8	-1.7	-0.2	-1.6
Qualifications: None of the above	1.3	2.8	4.0	2.0	2.0	0.5
Qualifications: A levels/AS levels or equivalent	1.3	2.8	4.9	-2.2	-1.5	-1.1
Medication: Lansoprazole	1.3	1.4	2.4	1.1	-0.9	1.5
Gout (self-reported)	1.3	1.7	2.8	-1.1	-1.7	-1.1
Birth weight	1.3	2.9	6.1	-2.5	-0.9	-1.3
Number of full sisters	1.3	1.6	4.0	0.5	2.0	-0.8
Supplements: Vitamin C	1.3	1.6	1.9	-1.4	-1.4	-1.0
Alcohol drinker status: Never	1.3	1.6	2.6	-1.4	0.5	-1.6
Frequency of depressed mood in last 2 weeks	1.2	1.7	3.0	-1.7	-0.4	-1.4
Pack years adult smoking proportion	1.2	1.8	3.5	1.9	1.0	1.0
Number of live births	1.2	1.7	3.3	1.2	1.8	0.7
Medication: Ventolin 100micrograms inhaler	1.2	1.6	2.7	-1.6	-0.5	-1.3
Medication: Blood pressure	1.2	2.1	3.8	1.1	1.2	1.9
Qualifications: nursing, teaching	1.2	1.9	3.9	-2.0	-0.8	-1.1
Average weekly champagne plus white wine intake	1.2	1.6	1.8	1.3	1.2	1.4
Miserableness	1.2	2.0	5.7	-0.2	2.4	-0.5
Tinnitus: Yes, now most or all of the time	1.2	1.4	3.4	-0.4	-1.8	-0.9
Medication: Bendroflumethiazide	1.2	1.8	2.5	-1.3	-1.6	-1.2
Triglycerides	1.1	1.8	2.2	1.5	1.1	1.4
Hearing difficulty/problems: Yes	1.1	1.7	2.8	-1.0	-1.1	-1.7
Fluid intelligence score	1.1	2.3	4.8	-2.2	-1.3	-0.7
Pulse wave Arterial Stiffness index	1.1	1.3	1.9	1.0	1.0	1.4
Blood clot in the leg (DVT)	1.1	1.4	1.9	1.1	1.4	1.0
Family relationship satisfaction	1.1	1.4	2.2	-1.5	-0.6	-1.3
Illnesses of father: None of the above (group 1)	1.1	1.4	2.4	-1.1	-0.9	-1.5
Bipolar Disorder (2018)	1.0	1.6	2.3	1.5	0.9	1.3
Coronary Artery Disease (CAD)	1.0	1.2	3.3	-0.1	1.8	0.4
Blood Platelet Count	1.0	11.7	16.2	3.1	3.0	4.0
Chronotype (morning person)	1.0	2.2	3.1	-1.6	-1.8	-1.0
Age when periods started (menarche)	1.0	2.4	3.8	-1.3	-1.2	-1.9
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	1.9	-0.5	1.1	-1.4
Mouth/teeth dental problems	1.0	1.5	4.2	-0.5	-2.1	-0.1
Time employed in main current job	1.0	1.1	2.7	0.8	-0.2	1.6
Suffer from ‘nerves’	1.0	1.6	2.2	-1.5	-1.1	-1.2
Eye problems/disorders: Cataract	1.0	1.1	3.0	0.6	1.7	-0.3
Depressed Affect (Nagel 2018)	0.9	1.9	3.3	-1.8	0.4	-1.5
Angina	0.9	1.2	3.6	0.2	1.9	0.3
Vitamin and mineral supplements	0.9	1.2	2.0	1.4	0.9	0.8
Sitting height	0.9	6.1	9.4	-2.6	-3.1	1.4
Had menopause	0.9	1.1	2.4	-0.9	-1.6	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	3.0	-1.7	-0.2	-1.0
Long-standing illness, disability or infirmity	0.9	1.3	2.2	-0.6	1.5	1.2
Number of operations (self-reported)	0.9	1.3	3.7	-0.3	1.9	-0.4
Supplements: Calcium	0.9	1.0	2.3	-1.5	-0.4	-0.6
Alzheimer’s Disease (in mother)	0.8	1.0	2.3	0.3	1.5	-0.7
Ever used hormone-replacement therapy (HRT)	0.8	1.1	1.9	-1.1	-1.4	0.0
Maternal smoking around birth	0.8	1.2	3.4	-0.3	1.8	-0.3
Multivitamins +/- minerals	0.8	1.0	1.2	-1.0	-1.0	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	2.3	-1.3	-1.2	-1.5
Prospective memory result	0.8	1.0	2.1	0.9	-1.5	-0.0
Health satisfaction	0.8	1.0	2.8	0.3	1.7	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	1.3	1.1	1.0	0.4
Medication: Atorvastatin	0.8	1.0	2.2	-1.5	0.4	-0.9
Pack years of smoking	0.8	1.1	2.1	1.5	0.9	0.7
LDL Cholesterol	0.7	1.1	2.4	1.0	1.6	0.2
Hypothyroidism (self reported)	0.7	1.7	2.7	-1.5	-0.4	-1.6
Had other major operations	0.7	0.8	2.5	-0.0	1.6	-0.1
Exposure to tobacco smoke at home	0.7	0.7	2.1	0.1	-1.4	0.3
Birth weight of first child	0.7	1.3	2.5	-0.8	-0.8	-1.6
Number of full brothers	0.7	0.8	1.6	0.9	1.3	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.3	-1.5	-1.2	-0.6
Mood swings	0.7	1.3	2.6	-0.2	1.6	-1.1
Diabetes diagnosed by doctor	0.7	1.2	2.6	0.9	1.6	-0.1
Commuting to job workplace: Walk	0.7	0.7	2.0	-0.4	0.1	-1.4
Osteoporosis (self-reported)	0.7	0.9	1.6	-1.3	-0.4	-1.0
Number of self-reported non-cancer illnesses	0.7	1.2	3.3	0.1	1.8	0.5
High cholesterol (Self-reported)	0.7	1.3	3.9	-0.1	2.0	0.0
Bipolar Disorder (2011)	0.6	0.5	1.5	0.2	0.2	1.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.0	-0.1	-0.3	-1.4
Blood Red Count	0.6	6.1	9.1	-2.5	-3.0	-1.7
Allergy or Eczema	0.6	1.5	1.9	-1.4	-1.4	-0.8
Serious illness, injury or assault to yourself	0.6	0.8	1.3	-1.1	-0.9	-0.4
Diabetes (self-reported)	0.6	0.9	1.7	1.0	1.3	-0.2
Medication: Simvastatin	0.6	0.9	1.2	0.6	1.0	1.1
Hair/balding pattern: Pattern 3	0.6	0.9	1.4	1.0	-0.4	1.2
Illnesses of mother	0.6	0.7	1.9	0.4	-0.2	1.4
Medication: Paracetamol	0.6	0.9	2.0	0.1	1.4	-0.9
Comparative body size at age 10	0.6	1.7	2.4	-1.1	-1.6	-1.2
Number of children fathered	0.6	0.7	1.5	0.1	1.2	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.0	-0.7	-0.8	-1.0
Angina (self-reported)	0.6	0.8	2.2	-0.3	1.5	-0.2
Illnesses of siblings: Diabetes	0.6	0.7	1.9	-0.2	-1.4	0.5
Back pain experienced in last month	0.6	0.8	1.5	-0.4	-0.9	1.2
Mineral and other dietary supplements	0.6	0.9	1.2	1.0	1.1	0.5
Ever taken oral contraceptive pill	0.6	0.7	1.2	1.1	-0.4	0.9
Mother’s age at death	0.6	0.8	1.8	-0.7	-1.3	-0.3
Eye problems/disorders: Glaucoma	0.6	0.7	1.1	-1.0	1.0	-0.1
Medication: Paracetamol	0.6	0.9	1.4	-0.2	1.2	-1.1
Fractured/broken bones in last 5 years	0.6	0.8	1.7	-0.6	-1.3	-0.4
Unable to work because of sickness or disability	0.6	0.8	2.3	0.0	1.5	0.4
Crohns Disease (2017)	0.5	1.0	1.5	-1.2	-1.2	-0.3
Ulcerative Colitis (UC)	0.5	0.9	1.9	0.8	0.4	1.4
Type 2 Diabetes (T2D) (2018)	0.5	1.0	2.5	0.5	1.6	-0.5
Lung FEV1/FVC ratio	0.5	2.6	5.7	-1.4	0.6	-2.4
Pain all over the body in last month	0.5	0.6	1.1	-1.0	0.2	-0.7
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.5	-0.0	-1.2	-0.4
Leg fat percentage (right)	0.5	1.7	3.5	1.9	0.4	1.2
Medication: Allopurinol	0.5	0.6	1.2	-0.6	-1.1	-0.5
Mean time to correctly identify matches	0.5	0.9	1.3	-1.1	-0.4	-1.0
Had major operations	0.5	0.6	1.6	0.2	1.3	0.4
Arm fat percentage (left)	0.5	2.2	3.6	1.9	0.2	1.7
Breast cancer (self-reported)	0.5	0.5	0.9	-0.6	0.9	-0.6
Financial situation satisfaction	0.5	0.6	1.1	-0.7	0.6	-1.0
Diastolic blood pressure, automated reading	0.5	1.6	4.8	-0.2	-2.2	-0.0
Myopia	0.5	0.7	0.9	-0.7	0.8	-1.0
Heart disease (siblings)	0.5	0.7	1.9	0.1	1.4	0.2
Schizophrenia vs Biploar Disorder	0.4	0.5	0.7	-0.8	-0.2	-0.8
HbA1C	0.4	0.4	0.7	0.6	0.8	0.5
Systolic Blood Pressure	0.4	2.1	3.8	1.9	0.3	1.5
Average weekly spirits intake	0.4	0.5	0.9	-0.7	0.3	-1.0
Fed-up feelings	0.4	0.7	1.1	-1.1	-0.2	-0.9
Taking other prescription medications	0.4	0.6	0.7	-0.8	0.6	0.8
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.9	-0.9	-0.4	-0.8
Allergy	0.4	0.8	2.1	0.6	1.4	-0.0
Illnesses of siblings	0.4	0.5	1.6	0.0	1.3	0.2
Arm fat percentage (right)	0.4	1.8	3.4	1.8	0.2	1.4
Trunk fat-free mass	0.4	2.2	4.2	-1.3	-2.0	0.8
Noisy workplace	0.4	0.5	1.1	1.1	-0.7	0.0
Trunk predicted mass	0.4	2.1	3.9	-1.3	-2.0	0.8
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.2	-0.0	0.5	-1.1
Glaucoma (self-reported)	0.4	0.5	1.1	-1.1	-0.1	-0.6
High blood pressure (siblings)	0.4	0.6	1.2	1.1	-0.6	0.5
Arm fat-free mass (right)	0.4	1.8	3.6	-1.1	-1.9	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	0.9	-1.0	0.6	-0.7
Alcohol intake frequency.	0.4	1.0	1.5	-0.6	1.0	-1.2
Overall health rating	0.4	0.8	2.2	-1.5	0.0	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	0.7	0.8	0.3	-0.8
Whole body fat-free mass	0.4	2.1	3.9	-1.4	-2.0	0.7
Leg fat-free mass (right)	0.4	1.9	3.8	-1.4	-1.9	0.4
Leg fat percentage (left)	0.4	1.3	2.6	1.6	-0.1	1.1
Average weekly beer plus cider intake	0.4	0.6	1.6	1.3	0.4	0.4
Alcohol drinker status: Previous	0.4	0.5	0.7	-0.8	0.7	-0.5
Body Mass Index (BMI) (2010)	0.3	0.5	0.8	0.9	-0.5	0.6
Ulcerative Colitis	0.3	0.4	0.7	0.6	0.8	0.5
Waist Hip Ratio (WHR)	0.3	1.3	3.1	-1.8	-0.9	-0.3
Number of treatments/medications taken	0.3	0.5	1.0	-0.3	1.0	0.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.9	-0.4	0.3	1.0
Systolic blood pressure, automated reading	0.3	0.7	1.5	1.2	0.1	0.9
Diabetes (mother)	0.3	0.4	0.5	0.7	0.6	-0.5
Leg fat-free mass (left)	0.3	1.4	2.7	-1.1	-1.6	0.5
Townsend deprivation index at recruitment	0.3	0.4	0.6	0.7	0.8	-0.3
Stomach or abdominal pain in last month	0.3	0.4	0.6	0.7	-0.7	-0.1
Supplements: Glucosamine	0.3	0.3	0.9	0.2	-0.2	1.0
Medication: Atenolol	0.3	0.4	1.0	0.1	0.5	1.0
Impedance of leg (left)	0.3	1.5	2.1	-1.3	-1.5	-0.7
Leg predicted mass (left)	0.3	1.4	2.8	-1.1	-1.7	0.5
Weight	0.3	1.3	3.0	-0.4	-1.7	0.8
Impedance of arm (right)	0.3	1.3	2.3	-1.5	-1.0	-0.8
Father’s age at death	0.3	0.4	0.9	-0.4	-1.0	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	0.7	-0.7	-0.2	-0.9
Pulse rate	0.3	0.6	1.4	0.5	-0.1	1.2
Depression (self-reported)	0.3	0.4	1.2	0.0	1.1	-0.1
Lung cancer (father)	0.3	0.4	1.1	0.2	-1.1	-0.2
Tense / ‘highly strung’	0.3	0.6	1.1	-0.5	-0.6	-1.1
Headache pain in last month	0.3	0.5	0.8	0.7	0.9	0.4
Hypothyroidism/myxoedema (self-reported)	0.3	0.7	1.2	-0.9	0.0	-1.1
Medication: Amlodipine	0.3	0.4	0.8	0.5	-0.5	0.9
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.6	-0.2	0.7	-0.8
Arm predicted mass (right)	0.3	1.6	2.8	-1.3	-1.7	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.5	0.6	0.3	0.7
Loneliness, isolation	0.3	0.4	1.1	0.4	1.0	-0.1
Osteoarthritis (self-reported)	0.3	0.4	0.6	0.8	0.6	0.4
Whole body water mass	0.3	1.8	3.3	-1.2	-1.8	0.7
Leg predicted mass (right)	0.3	1.8	3.5	-1.3	-1.9	0.5
Commuting to job workplace: Public transport	0.3	0.4	0.7	0.8	-0.5	-0.4
Basal metabolic rate	0.3	1.8	3.6	-1.1	-1.9	0.7
Arm fat-free mass (left)	0.3	1.6	3.2	-1.2	-1.8	0.5
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.9	-0.4	-0.8	-1.4
Arm predicted mass (left)	0.3	1.5	2.8	-1.2	-1.7	0.4
Major Depression (MDD)	0.2	0.3	0.4	-0.5	-0.6	-0.4
Mean Putamen Volume	0.2	0.2	0.4	0.5	0.6	-0.2
Rheumatoid Arthritis	0.2	0.3	0.8	-0.2	0.1	-0.9
Blood White Count	0.2	1.4	3.9	0.4	-2.0	-0.1
Respiratory disease	0.2	0.5	1.2	0.0	0.6	1.1
Relative age of first facial hair	0.2	0.5	1.3	-0.1	1.2	-0.0
Medication: Co-codamol	0.2	0.3	0.4	-0.6	-0.5	-0.4
Current tobacco smoking	0.2	0.3	0.4	-0.3	0.6	-0.6
Relative age voice broke	0.2	0.3	0.4	-0.3	0.7	-0.5
High blood pressure	0.2	0.5	1.3	0.3	0.5	1.1
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.6	-0.5	-0.8	-0.7
High blood pressure (mother)	0.2	0.3	0.8	-0.3	0.1	-0.9
Body mass index (BMI)	0.2	1.0	2.4	1.6	0.2	0.7
Trunk fat mass	0.2	0.9	1.5	0.0	-1.2	1.1
Hair/balding pattern: Pattern 2	0.2	0.3	0.6	-0.4	-0.0	-0.8
Hair/balding pattern: Pattern 4	0.2	0.5	0.8	0.0	0.9	0.9
Pulse wave reflection index	0.2	0.3	0.6	0.3	0.8	0.3
Loud music exposure frequency	0.2	0.3	0.4	-0.4	-0.4	-0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.5	-0.7	-0.1	0.6
Body fat percentage	0.2	0.7	1.1	0.9	-0.4	1.1
Exposure to tobacco smoke outside home	0.2	0.2	0.5	-0.4	-0.7	0.2
Emphysema/chronic bronchitis	0.2	0.3	0.8	0.2	-0.1	0.9
Medication for pain relief, constipation, heartburn	0.2	0.4	0.6	-0.7	-0.8	-0.2
Neck or shoulder pain in last month	0.2	0.2	0.6	-0.4	-0.1	-0.8
Whole body fat mass	0.2	0.6	1.3	0.2	-1.1	0.8
Leg fat mass (right)	0.2	0.6	0.7	0.8	-0.8	0.8
Leg pain on walking	0.2	0.2	0.5	0.7	-0.2	0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	-0.5	-0.5	0.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.5	-0.5	-0.7	-0.2
Average weekly red wine intake	0.2	0.4	0.9	-1.0	-0.3	-0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.4	0.5	0.7	0.2
Medication for cholesterol	0.2	0.4	0.5	0.7	0.6	0.5
Arm fat mass (left)	0.2	0.8	1.3	0.8	-0.6	1.1
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.5	-0.7	-0.3	-0.5
Pain experienced in last month	0.2	0.4	0.8	0.4	-0.5	0.9
Basal cell carcinoma (self-reported)	0.2	0.2	0.4	-0.3	-0.7	-0.2
Impedance of whole body	0.2	0.8	1.7	-1.3	-0.7	-0.4
Leg fat mass (left)	0.2	0.8	1.3	0.7	-1.1	0.8
Irritable Bowel Disease (IBD)	0.1	0.3	0.6	-0.3	-0.3	0.8
Reaction Time	0.1	0.3	0.6	-0.3	0.1	-0.8
Fasting Glucose	0.1	0.1	0.4	0.0	-0.7	0.0
Neuroticism (2016)	0.1	0.1	0.3	0.2	0.1	-0.6
Cardiovascular Disease	0.1	0.3	0.4	0.5	0.6	0.5
Medication for hormone replacement therapy	0.1	0.2	0.3	-0.2	-0.6	0.2
Diabetes (father)	0.1	0.1	0.2	0.4	0.2	0.4
Impedance of leg (right)	0.1	0.5	0.7	-0.8	-0.7	-0.5
Trunk fat percentage	0.1	0.5	1.0	0.4	-0.6	1.0
Average weekly fortified wine intake	0.1	0.1	0.3	0.1	0.1	0.5
Tinnitus: Yes, but not now, but have in the past	0.1	0.2	0.3	0.4	0.5	0.0
Chronic bronchitis/emphysema (father)	0.1	0.2	0.4	0.3	0.6	-0.1
Waist circumference	0.1	0.3	0.6	-0.0	-0.7	0.6
Number of incorrect matches in round	0.1	0.2	0.4	0.6	0.5	0.2
Alcohol usually taken with meals	0.1	0.2	0.6	-0.1	0.8	0.3
Financial difficulties in last 2 years	0.1	0.1	0.2	0.5	-0.4	-0.1
Heart attack	0.1	0.1	0.2	-0.3	-0.1	-0.4
Hip circumference	0.1	0.3	0.8	0.1	-0.9	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.3	0.4	0.1	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	0.4	-0.2	0.0
Impedance of arm (left)	0.1	0.4	0.8	-0.9	-0.5	0.1
Arm fat mass (right)	0.1	0.6	1.0	0.8	-0.4	1.0
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	-0.4	0.1	-0.4
Medication: Ibuprofen	0.1	0.1	0.3	0.5	0.1	0.0
Medication: Seretide 50 evohaler	0.1	0.1	0.3	0.1	-0.2	0.5
Heart disease (mother)	0.1	0.2	0.4	-0.2	0.6	0.2
Pulse rate, automated reading	0.1	0.2	0.6	-0.1	-0.7	-0.1
Knee pain experienced in last month	0.1	0.1	0.2	0.3	-0.4	0.4
Hypertension (Self-reported)	0.1	0.4	0.6	0.1	0.8	0.8
Illnesses of father: Heart disease	0.1	0.1	0.4	-0.0	0.0	0.6
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.4	-0.6	-0.5	0.1
Smoking status: Current	0.1	0.2	0.6	0.1	0.8	-0.2
Hearing aid user	0.1	0.1	0.2	-0.4	0.4	-0.1
Medication: Blood pressure	0.1	0.2	0.3	-0.4	-0.4	-0.5
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.2	0.4	-0.4	-0.2
Illnesses of father: High blood pressure	0.1	0.1	0.2	-0.4	-0.4	0.2
Irritability	0.1	0.2	0.2	0.5	-0.4	-0.3
Risk taking	0.1	0.1	0.2	0.0	0.4	0.4
Commuting to job workplace: Cycle	0.1	0.2	0.2	0.3	-0.4	-0.5
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.1	0.2	-0.1	-0.1	0.4
Blood Eosinophil Count	0.0	0.1	0.1	0.2	-0.1	0.4
Heel T-Score	0.0	0.2	0.4	0.6	-0.2	-0.6
BMI	0.0	0.2	0.5	0.7	0.0	-0.4
Hair Pigment	0.0	0.5	1.1	0.6	1.1	0.1
Tanning	0.0	0.2	0.4	0.2	0.6	0.3
Severe depression (siblings)	0.0	0.0	0.1	0.2	-0.1	0.2
Medication: Levothyroxine sodium	0.0	0.1	0.2	0.0	0.5	-0.1
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	0.3	0.0	-0.0
Asthma	0.0	0.0	0.1	-0.3	-0.1	0.1
Wheeze or whistling in the chest in last year	0.0	0.0	0.0	-0.1	0.0	-0.1
Ever had bowel cancer screening	0.0	0.0	0.0	0.2	0.2	0.1
Asthma (self-reported)	0.0	0.1	0.2	0.1	0.0	0.4
Medication: Lisinopril	0.0	0.0	0.0	0.1	-0.2	0.1
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.1	-0.1	-0.2	0.3
Heart attack/myocardial infarction (self-reported)	0.0	0.1	0.1	-0.3	0.0	-0.3

Hub : Genes

SLCO1C1

Models

Trait associations