TWAS hub - SLFN12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0640	0.0290	1.4e-02	0.081	0.024	0.060	0.077	0.079	3.9e-10	5.1e-04	9.0e-08	1.2e-09	8.0e-10
2	GTEx	Adipose Subcutaneous	0.4480	0.0590	5.1e-13	0.264	NA	0.277	NA	0.287	1.2e-21	NA	9.2e-23	NA	1.2e-23
3	GTEx	Breast Mammary Tissue (Male)	0.3332	0.1509	8.3e-02	0.024	NA	0.039	NA	0.087	9.1e-02	NA	4.4e-02	NA	4.8e-03
4	GTEx	Cells EBV-transformed lymphocytes	0.3370	0.1210	3.5e-03	-0.005	NA	-0.008	NA	-0.009	4.9e-01	NA	7.3e-01	NA	9.4e-01
5	GTEx	Cells Transformed fibroblasts	0.3290	0.0730	5.4e-06	0.119	NA	0.194	NA	0.226	3.3e-09	NA	1.7e-14	NA	6.4e-17
6	GTEx	Esophagus Mucosa	0.1760	0.0700	6.2e-03	0.119	NA	0.071	NA	0.107	2.4e-08	NA	1.8e-05	NA	1.3e-07
7	GTEx	Esophagus Muscularis	0.2300	0.0680	6.0e-04	0.168	NA	0.161	NA	0.168	2.1e-10	NA	5.3e-10	NA	2.0e-10
8	GTEx	Skin Sun Exposed Lower leg	0.1890	0.0660	3.2e-03	0.132	NA	0.110	NA	0.106	4.7e-11	NA	2.3e-09	NA	4.1e-09
9	GTEx	Stomach	0.2880	0.0800	1.8e-04	0.180	NA	0.100	NA	0.177	5.5e-09	NA	1.6e-05	NA	7.7e-09
10	GTEx	Whole Blood	0.1840	0.0630	2.7e-04	0.049	NA	0.109	NA	0.067	2.4e-05	NA	3.0e-10	NA	8.2e-07
11	METSIM	Adipose	0.2092	0.0613	7.0e-05	0.024	0.043	0.098	0.117	0.026	1.4e-04	3.8e-07	1.9e-14	4.3e-17	7.3e-05
12	YFS	Blood	0.1508	0.0340	9.3e-09	0.043	0.032	0.054	0.060	0.044	4.9e-14	7.9e-11	4.9e-17	6.5e-19	2.7e-14
13	TCGA	Bladder Urothelial Carcinoma	0.0670	0.0320	2.1e-03	0.044	0.018	-0.001	NA	0.019	1.3e-04	1.0e-02	4.2e-01	NA	9.2e-03
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0384	0.0191	4.9e-03	0.012	0.016	0.008	NA	0.013	1.6e-02	5.7e-03	3.4e-02	NA	1.1e-02
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0430	0.0234	7.7e-03	0.010	0.013	0.009	NA	0.011	2.2e-02	1.1e-02	3.2e-02	NA	1.7e-02
16	TCGA	Brain Lower Grade Glioma	0.1775	0.0513	5.8e-10	0.130	0.070	0.113	NA	0.125	1.4e-14	2.1e-08	9.6e-13	NA	4.7e-14
17	TCGA	Lung Adenocarcinoma	0.0519	0.0220	3.7e-04	0.019	0.032	0.038	NA	0.030	2.5e-03	9.8e-05	2.6e-05	NA	1.9e-04
18	TCGA	Prostate Adenocarcinoma	0.1137	0.0388	1.9e-07	0.096	0.075	0.091	NA	0.100	3.4e-10	2.7e-08	9.3e-10	NA	1.2e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Supplements: Fish oil (including cod liver oil)	5.8	7.6	11.7	-3.2	-3.3	-2.0	-1.5	-3.1	-3.4	-2.7	-3.0	-3.1	-3.1	-2.0	-3.1	-2.6	-2.3	-2.1	-3.2	-1.7	-2.8
Mineral and other dietary supplements	5.5	7.4	12.2	3.4	3.3	2.0	0.9	3.2	3.5	2.8	3.2	3.3	2.5	2.4	3.3	2.7	1.9	1.9	3.4	1.1	2.6
Fasting Glucose	5.2	6.2	11.6	-2.6	-2.5	-2.6	-2.3	-1.2	-2.4	-3.1	-3.2	-3.0	-2.2	-2.4	-3.1	-2.3	-1.7	-1.6	-2.6	-1.2	-3.4
Chronic bronchitis/emphysema (mother)	4.8	5.6	10.9	-2.3	-2.1	-1.9	-2.5	-2.3	-2.5	-2.3	-2.2	-2.5	-3.3	-2.6	-2.1	-2.4	-2.3	-1.9	-2.2	-2.3	-2.6
Supplements: Glucosamine	4.1	5.3	10.1	-2.9	-2.5	-2.4	-1.4	-1.8	-2.4	-2.8	-3.2	-2.8	-1.6	-2.9	-3.2	-2.1	-0.9	-0.8	-2.8	-0.5	-1.9
Mouth/teeth dental problems: Bleeding gums	3.7	4.8	7.9	2.4	2.5	1.4	0.9	2.7	2.3	2.3	2.5	2.1	1.6	1.2	2.1	2.6	2.2	2.3	2.5	2.8	1.9
Average weekly fortified wine intake	3.6	4.2	8.9	2.4	2.7	2.7	-0.1	0.8	1.9	3.0	2.3	2.9	0.7	2.1	2.2	2.0	-0.1	1.1	2.3	-0.2	2.9
Birth weight	3.3	7.1	11.7	3.0	2.9	2.1	0.9	2.5	2.7	2.6	3.3	2.7	2.7	3.4	3.2	3.1	2.0	2.6	3.0	1.6	2.1
Ever had hysterectomy (womb removed)	3.1	3.5	8.4	2.4	2.7	2.4	0.6	1.1	2.0	2.3	1.8	2.3	1.3	0.9	1.7	2.9	0.5	1.5	2.4	0.4	1.8
Medication: Ramipril	3.1	4.0	7.4	2.0	1.6	1.4	1.4	2.4	2.5	1.7	2.2	2.1	2.2	1.3	2.1	1.6	2.7	1.9	2.1	1.8	2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.1	4.0	8.7	-2.0	-2.0	-0.8	-2.5	-1.7	-2.1	-1.7	-2.5	-2.6	-2.3	-1.5	-1.6	-2.0	-1.2	-1.7	-2.0	-1.6	-3.0
Eye problems/disorders: Diabetes related eye disease	2.9	3.2	5.2	1.8	2.1	0.6	2.1	2.2	2.0	1.4	2.1	1.2	2.1	2.3	2.1	1.7	0.9	2.0	1.9	1.1	0.8
Illnesses of siblings	2.8	3.9	6.4	-2.4	-2.4	-1.3	-2.3	-2.5	-2.3	-2.0	-2.3	-1.8	-1.7	-1.2	-2.2	-2.5	-1.1	-1.6	-2.4	-1.5	-0.9
Illnesses of siblings: Diabetes	2.5	3.1	6.7	1.5	1.8	0.4	2.1	2.3	1.9	1.1	1.9	1.1	2.6	1.7	1.5	1.7	1.5	2.5	1.6	2.0	0.9
Heart disease (siblings)	2.5	3.1	5.2	2.0	1.8	1.8	2.3	1.9	1.6	1.9	2.2	1.4	1.8	0.5	1.9	2.1	1.3	1.9	2.0	1.4	0.6
Ulcerative Colitis (UC)	2.4	4.5	7.1	2.5	2.3	2.0	1.6	1.8	2.4	2.3	2.5	2.6	2.2	1.5	2.4	2.7	1.0	1.2	2.5	0.8	2.4
Had other major operations	2.3	2.8	5.0	-2.1	-1.6	-1.3	-0.1	-1.8	-2.2	-1.6	-2.1	-2.1	-1.3	-0.9	-1.3	-2.1	-1.8	-1.3	-2.0	-1.2	-2.0
Number of live births	2.3	3.2	7.0	-2.4	-2.1	-2.6	0.3	-1.1	-1.7	-2.4	-1.6	-2.3	-0.8	-1.7	-2.0	-2.0	-1.1	-0.5	-2.2	-1.0	-1.8
Pulse wave Arterial Stiffness index	2.3	2.7	5.1	1.6	2.2	1.1	1.7	1.5	1.7	1.8	1.9	1.8	2.1	0.1	1.3	2.0	1.1	1.1	1.6	1.6	2.0
Medication: Seretide 50 evohaler	2.3	2.6	5.2	-1.7	-1.9	-1.0	-0.9	-1.4	-1.8	-1.7	-2.3	-1.8	-1.7	-1.7	-1.9	-1.3	-0.9	-1.4	-1.7	-1.2	-2.1
Hearing aid user	2.3	2.5	5.0	2.1	2.0	1.8	1.8	1.3	1.8	2.2	1.8	1.8	1.0	1.1	2.1	1.6	0.1	0.4	2.0	-0.4	1.1
Blood Platelet Count	2.1	24.3	51.0	5.0	4.6	5.2	4.5	3.6	4.4	4.6	5.8	5.3	7.1	4.6	4.5	5.2	4.2	5.7	5.1	3.3	4.6
Financial difficulties in last 2 years	2.1	2.9	7.0	-1.6	-1.6	-1.6	-1.7	-1.1	-1.7	-1.6	-1.7	-2.1	-2.1	-1.8	-1.5	-1.5	-1.8	-0.7	-1.6	-1.0	-2.7
Pulse wave peak to peak time	2.1	2.5	5.1	-1.6	-2.3	-1.1	-1.6	-1.5	-1.7	-1.8	-1.9	-1.6	-2.0	-0.1	-1.3	-1.9	-1.0	-1.1	-1.6	-1.5	-1.8
Neck or shoulder pain in last month	2.1	3.0	5.6	-1.7	-1.4	-0.3	-0.7	-2.2	-2.1	-0.7	-1.7	-1.5	-2.0	-2.1	-1.8	-2.4	-2.3	-0.9	-1.6	-2.2	-1.4
Financial situation satisfaction	2.1	2.6	5.2	-1.4	-1.7	-0.5	-2.0	-2.3	-1.8	-1.0	-1.4	-1.0	-1.8	-1.9	-1.5	-1.8	-1.7	-1.8	-1.5	-1.8	-0.7
Diabetes (self-reported)	1.8	2.8	5.3	1.7	1.7	1.1	0.8	1.5	1.6	1.5	1.8	1.5	1.6	1.9	1.9	1.4	2.1	2.0	1.7	2.3	1.7
Pulse wave reflection index	1.8	2.2	5.6	1.2	1.5	1.2	1.5	1.3	1.3	1.2	1.5	1.3	2.1	0.0	0.8	1.3	2.0	1.8	1.3	2.4	1.7
Medication: Allopurinol	1.8	2.3	4.9	-1.9	-1.5	-0.5	-0.5	-1.9	-2.2	-1.4	-2.1	-1.9	-0.8	-1.0	-1.4	-2.0	-1.0	-0.6	-1.8	-1.0	-2.0
Cholesterol lowering medication	1.8	2.7	6.5	-1.9	-1.3	-2.2	1.4	-1.1	-1.7	-1.8	-1.4	-2.0	-1.2	-2.5	-2.2	-1.7	-1.2	-0.2	-1.8	-0.4	-1.6
Irritable Bowel Disease (IBD)	1.7	4.0	6.0	2.2	1.8	1.5	1.8	2.2	2.4	2.1	2.5	2.3	2.1	1.2	2.1	2.2	1.4	1.8	2.3	1.5	2.2
Vitamin and mineral supplements	1.7	2.4	5.0	1.7	1.4	1.4	0.1	2.2	2.1	1.7	1.5	1.6	1.3	1.0	1.4	1.5	1.0	2.1	1.8	0.7	1.4
Maternal smoking around birth	1.7	2.4	5.8	-0.9	-1.1	0.2	-1.8	-2.4	-1.8	-0.5	-1.2	-0.9	-1.6	-2.1	-1.4	-1.4	-1.9	-2.4	-1.0	-2.0	-1.1
Pain all over the body in last month	1.7	1.8	3.2	1.6	1.5	1.6	0.9	0.9	1.4	1.4	1.0	1.7	1.5	1.2	1.8	1.4	1.1	0.2	1.5	0.4	1.6
Number of full brothers	1.7	2.1	4.8	-1.3	-1.4	-0.4	-1.0	-2.1	-1.7	-1.2	-1.3	-1.3	-1.3	-1.1	-1.0	-1.4	-1.4	-2.2	-1.4	-1.9	-1.6
Ever used hormone-replacement therapy (HRT)	1.6	2.0	4.3	-1.6	-1.1	-1.3	0.2	-1.8	-1.7	-1.3	-1.2	-1.7	-0.5	-1.2	-1.6	-1.1	-1.8	-0.4	-1.6	-2.1	-1.8
Number of full sisters	1.6	1.9	4.2	1.6	1.0	0.2	1.1	2.1	1.8	0.8	1.2	1.2	1.6	1.2	0.8	2.0	1.8	1.1	1.6	1.7	0.8
Commuting to job workplace: Car/motor vehicle	1.6	1.8	4.0	-1.3	-1.7	-1.3	-0.7	-0.7	-1.3	-1.5	-2.0	-1.3	-1.9	-1.6	-1.8	-1.1	-0.6	-0.3	-1.2	-0.9	-1.4
Handedness (chirality/laterality): Left-handed	1.6	2.0	3.3	-1.8	-1.5	-1.8	0.0	-1.1	-1.5	-1.7	-1.3	-1.8	-1.8	-0.1	-1.1	-1.6	-0.8	-1.3	-1.8	-0.5	-1.6
Medication: Atorvastatin	1.6	1.9	4.2	1.4	2.0	1.9	0.8	0.3	1.0	1.8	1.4	1.6	0.8	1.4	1.7	1.3	-0.9	1.5	1.5	-0.4	1.7
Multivitamins +/- minerals	1.5	1.9	3.0	-1.6	-1.3	-1.3	-0.1	-1.7	-1.7	-1.5	-1.5	-1.6	-1.4	-1.3	-1.4	-1.5	-1.2	-1.6	-1.6	-0.7	-1.4
Gout (self-reported)	1.5	2.1	6.2	-1.3	-1.2	0.5	-0.5	-2.5	-2.1	-0.7	-1.9	-1.1	-1.1	-0.8	-1.1	-1.9	-1.7	-0.8	-1.4	-1.9	-1.5
Osteoarthritis (self-reported)	1.5	2.0	3.3	-1.4	-1.1	-1.1	-1.5	-1.8	-1.6	-1.1	-1.6	-1.4	-1.2	-1.8	-1.6	-1.1	-1.7	-0.6	-1.4	-1.2	-1.3
Number of treatments/medications taken	1.4	2.4	6.0	-1.6	-0.9	-0.5	-0.1	-2.2	-1.9	-0.9	-1.4	-1.6	-1.4	-1.1	-1.0	-1.7	-2.4	-1.6	-1.6	-2.4	-1.7
Frequency of depressed mood in last 2 weeks	1.3	1.8	6.1	-1.2	-1.5	-1.1	-1.7	-1.2	-1.4	-1.2	-1.1	-1.4	-2.5	-1.6	-1.1	-0.9	0.1	-1.4	-1.3	-0.4	-1.3
Prospective memory result	1.3	1.6	4.9	-1.5	-1.4	-0.8	0.2	-1.3	-1.6	-1.4	-2.2	-1.3	-1.0	-1.0	-1.5	-1.4	-1.1	-0.3	-1.5	-1.0	-1.3
Lung cancer (father)	1.3	1.5	5.0	-1.1	-1.1	-1.1	-1.7	-0.8	-1.2	-1.3	-1.6	-1.2	-2.2	-1.6	-1.5	-0.7	-0.4	-0.3	-1.2	0.1	-1.2
Ever highly irritable/argumentative for 2 days	1.3	1.6	4.2	-1.4	-1.8	-0.3	-0.3	-2.0	-1.5	-1.3	-1.3	-0.9	0.0	-1.5	-1.4	-0.8	-0.8	-1.6	-1.4	-1.2	-0.6
Blood clot in the leg (DVT)	1.3	1.6	3.2	-1.3	-1.3	-1.5	-0.7	-1.4	-1.3	-1.4	-0.5	-1.2	-1.8	-1.1	-1.4	-1.4	-1.4	-0.9	-1.3	-1.4	-1.2
Loneliness, isolation	1.3	1.7	5.2	-1.6	-1.8	-1.4	-0.2	-0.3	-1.2	-1.4	-1.8	-2.1	-1.2	-1.1	-1.1	-0.9	-0.1	-0.4	-1.6	0.2	-2.3
Number of operations (self-reported)	1.3	1.9	9.2	-1.0	-0.8	0.5	-1.1	-2.0	-1.5	-0.1	-1.4	-0.8	-1.6	-0.4	-0.1	-1.9	-1.9	-1.5	-0.9	-3.0	-0.7
Coronary Artery Disease (CAD)	1.2	1.4	2.9	1.2	1.2	1.0	1.7	0.4	0.8	1.1	1.7	1.4	1.6	0.7	0.8	0.0	1.0	1.4	1.2	1.6	1.4
Lupus	1.2	1.9	3.7	1.7	1.9	0.9	-0.6	1.6	1.7	1.4	1.8	1.4	0.5	0.9	1.5	1.9	0.8	0.1	1.7	1.4	1.1
Schizophrenia (2014)	1.2	2.6	6.6	1.9	1.7	1.4	-0.3	1.3	1.8	1.9	2.0	1.8	1.0	1.9	1.8	2.6	0.6	0.9	1.9	0.9	1.4
Mouth/teeth dental problems	1.2	1.8	4.0	-1.6	-1.5	-1.1	0.3	-2.0	-1.7	-1.6	-1.1	-1.1	0.0	-0.2	-1.5	-1.5	-1.3	-1.2	-1.7	-1.6	-1.0
Heart attack	1.2	1.5	3.6	1.5	1.4	1.9	-0.5	0.7	1.1	1.6	1.1	1.5	0.4	1.0	1.4	1.4	0.9	0.8	1.5	0.2	1.4
Medication: Paracetamol	1.2	1.8	6.2	-1.3	-1.0	0.1	-0.2	-2.5	-1.8	-0.4	-1.0	-0.6	-0.8	-0.8	-0.8	-1.8	-2.4	-1.6	-1.4	-2.0	-0.2
Happiness	1.1	1.4	5.8	-1.1	-1.3	-0.5	-0.8	-1.4	-1.3	-0.8	-1.2	-1.0	-2.4	-1.8	-1.0	-1.1	0.0	-1.1	-1.1	0.2	-0.5
High blood pressure (siblings)	1.1	1.6	4.1	1.5	1.4	0.8	2.0	1.1	1.3	1.4	1.3	1.6	0.8	0.2	1.2	1.6	0.5	0.3	1.5	1.1	1.4
Comparative body size at age 10	1.1	3.0	8.0	-2.0	-1.6	-2.8	-1.4	0.1	-1.0	-2.3	-2.1	-2.3	-2.3	-1.9	-2.1	-1.5	-0.6	0.2	-1.9	0.1	-1.4
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.3	5.0	1.6	1.6	2.0	0.4	0.2	1.2	1.8	1.7	2.2	1.5	2.2	2.0	1.4	0.5	-0.0	1.6	-0.0	2.1
Ever taken oral contraceptive pill	1.1	1.2	3.2	-1.2	-1.2	0.2	-1.3	-1.7	-1.4	-0.5	-1.1	-0.9	-0.8	0.1	-0.5	-1.8	-1.1	-1.3	-1.3	-1.2	-0.6
Commuting to job workplace: Public transport	1.1	1.3	4.0	-1.5	-0.9	-1.0	0.8	-1.4	-1.2	-0.9	-0.0	-1.4	0.9	-0.5	-0.3	-2.0	-1.1	-1.4	-1.5	-0.9	-1.1
Ever depressed for a whole week	1.1	1.4	2.4	-1.4	-1.5	-0.6	-1.4	-1.3	-1.4	-1.2	-1.4	-1.4	-0.3	-1.3	-1.2	-1.4	0.2	-1.0	-1.5	-0.2	-0.8
Heart attack/myocardial infarction (self-reported)	1.1	1.5	3.1	1.5	1.5	1.8	-0.4	0.8	1.2	1.5	1.1	1.4	0.4	1.0	1.5	1.4	1.0	0.8	1.6	0.3	1.3
Bipolar Disorder (2018)	1.0	1.6	4.4	-1.3	-1.4	-0.9	-0.5	-1.3	-1.3	-1.2	-1.4	-1.4	-2.1	-1.2	-1.4	-1.2	-0.5	-0.7	-1.3	-1.5	-1.7
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	6.5	-0.0	0.2	1.1	-0.8	-1.8	-0.9	0.5	-0.7	0.1	-1.0	-0.8	-0.2	0.2	-2.0	-1.0	-0.1	-2.5	-0.4
Sitting height	1.0	7.3	13.8	3.1	3.0	3.2	1.6	0.7	2.3	3.4	3.3	3.7	3.0	2.7	2.7	3.0	1.4	-0.0	2.9	0.8	3.6
Hair/balding pattern: Pattern 2	1.0	1.2	4.0	1.2	1.6	0.6	0.7	0.7	1.2	1.2	2.0	1.3	1.2	0.2	0.9	0.9	1.0	-0.2	1.1	1.0	1.5
Pain type(s) experienced in last month: Hip pain	1.0	1.2	4.2	1.0	1.1	0.1	0.5	1.8	1.3	0.5	1.1	0.5	1.0	0.6	0.9	1.2	1.3	2.0	1.1	1.2	0.6
Ulcerative Colitis	0.9	1.3	3.2	1.3	1.1	0.7	0.8	0.9	1.3	1.2	1.4	1.4	1.0	0.9	1.1	1.8	0.6	1.0	1.4	0.8	1.5
Sensitivity / hurt feelings	0.9	1.6	3.7	-1.3	-1.4	-1.0	-0.9	-1.2	-1.4	-1.2	-1.2	-1.3	-1.1	-1.9	-1.1	-1.6	-1.4	-0.7	-1.2	-1.4	-1.1
Angina	0.9	1.2	2.6	1.3	1.3	1.6	-0.0	0.8	1.2	1.3	0.7	1.2	-0.1	1.0	1.6	1.3	-0.7	0.4	1.3	-1.5	0.6
Supplements: Zinc	0.9	1.0	4.5	-0.9	-0.9	-0.2	-0.1	-1.8	-1.3	-0.5	-0.6	-0.5	-1.1	-0.9	-0.6	-1.6	0.1	-2.1	-1.0	-0.3	-0.0
Medication: Metformin	0.9	1.3	4.6	0.9	0.8	0.3	0.5	1.3	1.1	0.4	1.1	0.7	1.5	1.2	1.0	0.8	1.7	2.1	0.9	1.6	0.7
Had menopause	0.9	1.2	2.2	-1.2	-1.1	-1.1	-0.1	-0.9	-1.1	-1.1	-1.0	-1.5	-0.6	-1.4	-1.3	-0.8	-1.0	-0.5	-1.1	-1.2	-1.5
Medication: Cholesterol lowering	0.9	1.5	2.5	1.2	1.2	1.4	0.4	0.9	1.2	1.2	1.4	1.2	1.2	1.6	1.6	1.0	1.3	1.2	1.2	0.5	1.4
Depression (self-reported)	0.9	1.0	4.0	-0.5	-0.8	0.2	-1.5	-1.4	-0.9	-0.3	-0.2	-0.4	-1.3	-1.0	-0.3	-0.4	-0.9	-2.0	-0.5	-2.0	-0.5
Forced vital capacity (FVC), Best measure	0.9	3.5	7.8	2.4	2.2	2.2	0.3	1.1	2.1	2.5	2.0	2.8	1.3	1.1	1.8	2.0	-0.4	-0.1	2.3	0.2	2.7
Eye problems/disorders: None of the above	0.9	1.0	3.2	-0.9	-0.9	-0.9	-0.6	-1.4	-1.2	-1.1	-1.0	-0.8	-0.9	-0.9	-1.3	-0.7	-0.5	-1.8	-1.0	-0.5	-0.9
Ever had bowel cancer screening	0.9	1.0	3.5	-0.8	-0.0	0.2	-1.0	-0.9	-1.2	-0.6	-1.0	-1.1	-0.9	-0.5	-0.6	-1.2	-1.6	-0.1	-0.7	-1.9	-1.7
Friendships satisfaction	0.9	1.2	3.4	-1.0	-1.1	-0.6	-1.2	-1.5	-1.4	-0.7	-0.9	-1.1	-1.9	-1.1	-0.9	-0.9	-0.7	-0.6	-1.0	-0.7	-1.2
Medication for cholesterol	0.9	1.3	3.1	1.2	1.2	1.5	-1.2	0.6	0.9	1.4	0.8	1.3	0.6	1.8	1.6	0.8	0.3	-0.2	1.2	0.8	1.5
Schizophrenia (2018)	0.8	1.6	4.7	1.4	1.2	1.3	-1.4	0.8	1.2	1.7	1.6	1.3	0.9	1.4	1.2	2.2	0.2	0.3	1.3	0.7	1.1
Crohns Disease (2017)	0.8	1.7	2.9	1.3	0.7	0.8	1.4	1.6	1.5	1.3	1.5	1.3	1.3	0.7	1.1	1.0	1.3	1.7	1.3	1.7	1.5
HDL Cholesterol	0.8	1.3	3.1	1.1	1.0	0.1	1.1	1.3	1.4	0.8	1.7	1.1	1.3	0.5	1.0	1.3	1.5	0.6	1.1	0.9	1.2
Blood Eosinophil Count	0.8	6.3	12.0	3.0	3.5	2.0	2.3	2.9	3.0	2.8	2.0	2.9	2.6	2.1	2.9	3.2	0.2	1.2	3.1	0.8	1.9
Current tobacco smoking	0.8	1.3	5.8	0.1	-0.0	-1.6	0.5	1.8	1.1	-0.2	1.2	-0.1	0.6	0.2	0.4	0.7	1.8	1.8	0.2	2.4	0.6
Fed-up feelings	0.8	1.4	3.8	-1.0	-1.4	-0.2	-0.9	-1.0	-1.4	-0.9	-1.7	-1.2	-1.9	-1.9	-1.3	-1.0	0.4	-0.2	-1.0	0.2	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	6.4	-0.3	-0.1	-0.0	-0.6	-1.9	-1.1	-0.3	-0.3	-0.1	0.7	0.9	-0.2	-0.3	-1.2	-2.5	-0.5	-1.4	-0.5
Medication: Paracetamol	0.8	1.3	4.5	-1.0	-1.2	0.1	-0.7	-2.1	-1.5	-0.5	-0.8	-0.5	-0.6	-0.5	-0.6	-1.5	-1.7	-1.3	-1.1	-1.8	-0.1
Shortness of breath walking on level ground	0.8	0.9	3.9	-0.4	-0.7	0.1	0.5	-1.1	-0.8	-0.2	-0.9	-0.3	-1.1	-1.4	-0.7	-0.4	-1.3	-1.7	-0.4	-2.0	-0.8
Emphysema/chronic bronchitis	0.8	0.9	3.1	1.0	1.4	1.8	0.4	0.2	0.7	1.3	0.3	0.8	0.1	-0.2	0.9	1.1	-1.1	0.2	0.9	-1.5	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	2.2	0.7	0.9	1.4	0.6	0.3	0.5	1.2	0.8	0.9	1.3	0.7	0.7	0.8	0.7	1.3	0.7	1.5	1.0
Eye problems/disorders: Cataract	0.8	0.9	1.9	1.1	0.9	0.9	1.3	1.3	1.2	1.4	0.6	1.0	0.6	0.5	1.2	1.0	0.4	0.9	1.1	0.8	0.6
Smoking status: Current	0.8	1.3	6.4	-0.0	-0.1	-1.8	0.1	1.9	1.1	-0.4	1.2	-0.3	0.7	0.1	0.4	0.5	1.9	1.7	0.1	2.5	0.5
Mother’s age at death	0.8	1.0	3.3	-1.0	-1.1	-0.5	-0.8	-0.7	-1.0	-0.9	-1.4	-1.1	-1.0	-0.1	-0.6	-1.8	-0.5	-0.7	-1.0	-0.8	-1.2
Chronotype (morning person)	0.7	1.7	3.4	-1.4	-1.0	-1.3	0.2	-0.9	-1.2	-1.8	-1.4	-1.4	0.7	1.8	-0.8	-1.0	-0.6	-1.6	-1.4	-1.5	-1.8
Standing height	0.7	6.6	12.2	2.9	2.9	2.5	1.9	1.4	2.6	3.2	3.2	3.5	3.2	1.8	2.4	3.2	0.7	0.9	2.8	1.1	3.4
Exposure to tobacco smoke outside home	0.7	0.9	3.0	1.1	1.2	1.7	-0.8	0.5	0.9	1.2	0.8	1.0	0.6	0.6	1.1	0.8	0.8	-0.4	1.0	0.7	1.1
Mouth/teeth dental problems: Loose teeth	0.7	0.8	1.6	0.9	1.1	0.4	1.3	1.0	0.9	1.2	1.2	0.7	0.4	0.5	0.9	1.1	0.1	1.1	0.9	1.1	0.4
Angina (self-reported)	0.7	0.9	2.9	1.1	1.1	1.4	-0.1	0.7	1.0	1.1	0.5	0.9	-0.4	0.8	1.4	1.0	-0.9	0.3	1.1	-1.7	0.3
Heart disease (mother)	0.7	0.9	2.7	-0.6	-0.3	0.1	-0.5	-1.0	-1.0	-0.6	-1.3	-0.9	-0.4	-0.1	-0.6	-1.6	-0.9	-1.6	-0.6	-1.1	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.6	0.9	1.4	1.1	-0.3	0.3	0.6	1.0	0.5	0.9	0.4	0.6	1.0	1.6	-0.1	1.6	1.0	-0.1	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	5.5	0.2	-0.2	-0.1	0.6	0.4	0.1	0.0	0.9	-0.1	1.0	0.0	0.1	0.9	1.8	1.6	0.2	2.3	-0.1
Average weekly champagne plus white wine intake	0.7	1.0	3.0	0.7	0.5	0.2	1.4	0.9	0.9	0.4	1.2	1.0	0.5	1.1	0.9	0.5	1.7	0.4	0.7	1.6	1.5
Medication: Blood pressure	0.7	1.4	4.5	-0.9	-0.8	-2.0	1.7	-0.3	-0.6	-1.1	-0.5	-1.3	-1.1	-2.1	-1.4	-0.7	-0.6	-0.8	-0.8	-0.6	-1.6
Medication: Bendroflumethiazide	0.7	1.1	3.6	-1.2	-1.3	-1.9	-0.5	-0.7	-1.0	-1.6	-1.1	-1.1	-0.6	0.1	-0.9	-1.1	-0.6	-0.8	-1.2	-0.5	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.2	-0.9	-1.0	-1.4	-0.3	-0.9	-0.8	-1.1	-0.1	-0.8	-1.5	-1.0	-1.1	-1.0	-1.1	-0.7	-0.9	-1.0	-0.8
Pack years of smoking	0.7	1.0	2.1	1.2	0.9	0.7	0.3	1.2	1.3	0.9	1.0	1.0	0.1	0.4	1.4	1.4	1.1	1.1	1.3	0.8	0.5
Alzheimer’s Disease (in father)	0.6	0.7	2.3	-0.8	-0.6	-0.2	-0.5	-1.5	-1.2	-0.4	-0.6	-0.6	-0.3	-0.7	-0.7	-0.8	-1.1	-1.1	-0.9	-0.9	-0.2
Prostate Cancer	0.6	0.8	2.3	0.7	0.2	1.5	-1.5	0.9	0.6	0.7	0.9	0.4	-0.3	1.5	1.2	0.8	1.0	0.7	0.9	0.8	-0.0
HbA1C	0.6	0.7	2.6	0.7	0.6	0.3	-0.9	0.7	0.6	0.5	1.1	0.7	0.8	0.6	0.6	0.6	1.3	0.6	0.7	1.6	1.0
Blood Red Count	0.6	5.7	10.4	3.1	3.1	3.2	-0.4	1.9	2.5	2.8	2.7	3.2	0.9	1.4	2.6	2.4	1.5	1.3	3.0	1.0	2.8
Severe depression (siblings)	0.6	0.7	1.7	-0.8	-0.9	-1.0	-0.6	-0.7	-0.9	-0.9	-0.8	-1.1	-1.1	0.1	-0.5	-0.4	-0.3	-1.2	-0.8	-0.4	-1.3
Hand grip strength (right)	0.6	1.6	3.7	1.4	1.1	1.1	-0.3	1.2	1.5	1.3	1.7	1.6	0.9	0.9	1.2	1.5	1.2	0.3	1.3	1.0	1.9
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.7	-1.0	-1.6	-0.9	-1.3	-0.5	-0.8	-1.4	-0.9	-1.2	-1.3	-0.8	-0.7	-0.5	0.6	-0.4	-1.1	0.2	-1.0
Hearing difficulty/problems with background noise	0.6	1.0	2.4	1.2	0.7	1.1	1.5	0.9	1.2	1.2	0.9	1.3	0.2	0.0	1.0	1.0	0.3	0.4	1.2	0.4	1.5
Forced vital capacity (FVC)	0.6	2.5	6.7	1.9	1.6	2.1	0.6	0.8	1.6	2.1	1.6	2.5	1.1	0.9	1.5	1.6	-0.0	0.1	1.9	0.8	2.6
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.9	-1.0	-1.1	-0.2	-0.6	-0.7	-0.8	-0.7	-1.2	-1.1	-0.0	-1.2	-0.8	-1.4	0.4	-0.7	-1.0	0.3	-0.6
Pulse rate	0.6	1.1	3.5	0.7	1.1	0.8	-1.4	-0.5	0.2	1.0	0.9	0.7	-0.5	1.4	1.4	0.2	-1.2	-1.9	0.6	-1.5	0.3
Medication: Lansoprazole	0.6	0.6	2.6	0.5	0.7	1.4	-1.3	-0.2	0.2	1.0	-0.3	0.6	-0.6	-0.9	0.3	0.5	-1.6	0.3	0.4	-1.0	0.6
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	6.9	0.1	-0.3	0.4	-2.6	-1.1	-0.5	0.1	0.4	0.0	-1.4	0.6	0.4	-0.5	-0.2	-1.6	0.1	-1.2	-0.4
Wheeze or whistling in the chest in last year	0.6	1.0	2.2	-1.3	-1.1	-0.6	-0.9	-0.9	-1.2	-1.1	-1.2	-1.5	-0.2	-0.7	-0.6	-1.2	0.3	-1.0	-1.2	-0.7	-1.5
Age at first live birth	0.6	1.0	11.2	0.7	0.5	1.0	-3.3	-0.2	0.1	0.9	0.8	0.5	-0.7	1.1	0.7	0.0	0.1	-0.9	0.6	-0.2	-0.2
Comparative height size at age 10	0.6	3.5	6.9	2.2	2.2	1.8	2.0	1.4	1.9	2.5	1.8	2.2	2.5	1.1	1.6	2.6	-0.2	1.1	2.2	0.6	1.9
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	2.5	-0.6	-0.4	-0.7	-1.0	-0.7	-0.8	-0.6	-0.9	-0.6	-1.6	-0.0	-0.7	-0.9	-1.0	-1.2	-0.7	-0.7	-0.8
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	1.5	0.7	0.6	-0.3	1.0	0.7	0.9	0.8	1.2	0.7	0.3	1.2	1.1	1.2	0.5	0.7	0.6	1.1	1.1
Back pain experienced in last month	0.6	0.9	2.3	1.2	1.4	0.8	-0.7	1.4	1.1	1.0	1.0	0.7	-0.1	0.3	1.1	0.9	0.5	1.5	1.2	0.6	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	6.1	0.1	0.3	1.3	-2.5	-1.5	-0.6	0.8	0.1	0.3	-1.8	-0.2	0.1	-0.6	-2.1	-1.3	0.1	-1.5	0.3
Illnesses of father: High blood pressure	0.6	0.8	3.4	-0.7	-0.9	-1.6	-0.2	0.5	-0.3	-1.3	-0.9	-0.9	-0.2	-0.3	-0.5	0.0	1.3	0.1	-0.7	1.8	-0.7
Average weekly beer plus cider intake	0.6	0.8	2.5	1.1	0.6	0.0	0.6	1.6	1.5	0.5	0.8	0.9	0.6	0.5	0.8	1.3	0.4	0.8	1.0	0.6	0.8
Schizophrenia vs Biploar Disorder	0.5	0.6	2.2	0.9	1.1	0.5	1.0	1.0	0.9	0.7	0.5	1.0	1.5	0.4	0.3	0.0	-0.3	0.3	0.9	0.5	0.6
Major Depression (MDD)	0.5	0.7	1.9	1.0	1.0	1.0	0.2	1.4	1.1	1.3	0.1	0.7	0.1	-0.4	0.7	0.6	-0.3	0.6	1.1	0.5	0.7
Mean Putamen Volume	0.5	0.6	2.7	-0.5	-1.0	-0.9	-0.8	0.7	-0.1	-0.9	-0.6	-0.6	0.4	-0.2	-0.9	0.0	1.6	0.9	-0.4	1.4	-0.1
Neuroticism (2016)	0.5	0.7	1.9	-0.7	-1.1	-1.4	-0.2	0.2	-0.6	-1.0	-0.2	-1.1	-1.2	-0.6	-0.3	-0.4	1.1	0.2	-0.6	1.4	-0.8
Rheumatoid Arthritis	0.5	0.7	2.0	0.3	0.5	1.4	-1.0	-1.1	-0.3	0.9	-0.3	0.5	-1.3	0.8	0.7	-0.5	-1.2	-1.3	0.2	-1.2	0.3
Blood White Count	0.5	4.0	19.2	0.9	0.6	-0.7	1.2	1.6	1.3	0.0	2.7	1.1	2.7	1.3	0.8	1.1	4.4	2.5	0.9	4.0	2.0
Waist Hip Ratio (WHR)	0.5	2.2	6.6	1.2	1.1	1.6	1.3	0.9	1.0	1.6	1.1	1.4	2.6	1.6	1.1	1.0	1.1	2.4	1.3	1.6	1.8
Systolic Blood Pressure	0.5	2.3	9.3	1.0	0.6	-0.2	1.5	2.4	1.7	0.3	1.1	0.8	0.9	0.8	0.9	1.1	2.4	2.6	1.2	3.0	1.2
Pack years adult smoking proportion	0.5	0.8	1.7	1.0	0.6	0.5	-0.2	1.0	1.1	0.7	0.9	0.9	-0.0	0.3	1.1	1.3	1.1	1.1	1.0	1.0	0.6
Chronic bronchitis/emphysema (father)	0.5	0.6	3.6	0.5	0.7	0.3	1.0	0.9	0.7	0.1	0.5	0.5	0.4	-1.1	0.2	0.1	0.8	1.9	0.5	0.5	0.7
Body mass index (BMI)	0.5	2.2	5.2	-1.3	-1.0	-0.3	-1.9	-2.0	-1.8	-1.1	-1.0	-1.1	-2.0	-1.4	-1.4	-1.4	-1.4	-1.5	-1.3	-2.3	-1.4
Medication: Simvastatin	0.5	0.7	1.8	-0.7	-0.8	-1.3	0.5	0.4	-0.3	-1.2	-0.3	-1.0	-0.4	-1.3	-1.1	-0.5	1.3	0.5	-0.6	0.8	-0.7
Arm fat percentage (right)	0.5	2.0	5.6	-1.2	-0.6	0.4	-1.8	-2.1	-1.9	-0.7	-1.2	-1.0	-1.8	-1.1	-1.2	-1.3	-1.8	-0.9	-1.2	-2.4	-1.3
Time employed in main current job	0.5	0.6	1.8	-0.8	-0.3	-0.2	0.3	-0.9	-1.1	-0.4	-1.0	-0.8	-0.7	-1.3	-1.1	-0.8	-0.9	-0.2	-0.8	-0.3	-0.9
Noisy workplace	0.5	0.6	1.6	-0.6	-0.6	-0.8	0.6	0.0	-0.3	-0.8	-0.6	-0.8	-0.1	-1.2	-1.2	-0.3	-0.6	-1.3	-0.7	-0.2	-1.0
Asthma	0.5	1.0	7.7	-0.4	-0.1	-0.5	-2.8	-0.7	-0.4	-0.7	-0.2	-0.7	-0.3	-0.3	-0.3	-0.7	0.0	-1.9	-0.6	-1.4	-1.0
Glaucoma (self-reported)	0.5	0.6	2.3	0.9	1.2	1.2	-0.9	-0.0	0.5	1.5	1.0	0.8	-0.1	-0.0	0.9	0.6	-0.5	-0.2	0.8	-0.7	0.8
Medication: Amlodipine	0.5	0.7	2.9	-0.8	-0.6	-1.3	1.7	-0.3	-0.4	-0.9	-0.6	-0.8	0.0	-0.7	-1.0	-0.4	-0.2	-1.1	-0.9	-0.1	-0.7
Medication: Omeprazole	0.5	0.6	3.1	0.5	0.7	1.1	-0.4	-0.8	-0.2	0.8	-0.3	0.4	-1.8	-0.6	0.2	0.3	-0.9	-0.4	0.6	-1.4	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.8	-0.7	-0.6	-1.1	1.3	0.8	0.1	-0.6	-0.7	-0.6	0.1	-0.5	-0.6	-0.3	0.3	0.8	-0.6	1.7	0.0
Pulse rate, automated reading	0.5	1.8	6.3	1.3	1.6	0.9	-1.1	0.8	1.1	1.6	2.2	1.2	0.8	2.1	2.5	0.6	0.4	0.4	1.3	0.3	1.0
Leg pain on walking	0.5	0.7	2.0	-0.7	-0.8	-0.8	1.2	-1.4	-0.8	-0.4	0.1	-0.2	-0.4	-1.4	-1.1	-0.3	-0.9	-0.9	-0.7	-0.9	0.1
Qualifications: nursing, teaching	0.5	0.8	3.3	-0.6	-1.0	-0.4	-1.1	-0.7	-0.9	-0.8	-1.0	-0.7	-1.1	0.3	-0.8	-0.9	-0.2	-1.8	-0.6	-0.4	-1.1
Breast cancer (self-reported)	0.5	0.6	1.8	-0.8	-0.4	-1.1	-0.2	0.2	-0.3	-0.8	-0.3	-1.1	-1.3	-1.3	-0.6	-0.6	0.1	-0.4	-0.8	0.3	-1.1
Asthma (self-reported)	0.5	1.0	7.6	-0.5	-0.1	-0.5	-2.8	-0.9	-0.5	-0.7	-0.2	-0.8	-0.5	-0.2	-0.3	-0.7	-0.3	-1.7	-0.6	-1.6	-1.1
Irritability	0.5	0.8	6.0	0.2	-0.4	1.3	-2.4	-1.2	-0.6	0.2	0.1	0.4	-0.5	0.7	0.6	-0.5	0.5	-1.7	0.1	-0.9	0.0
Ever had prostate specific antigen (PSA) test	0.5	0.6	3.5	-0.0	-0.2	-0.1	-0.1	1.1	0.2	-0.6	-0.5	-0.3	0.9	0.2	-0.4	0.5	1.9	1.1	-0.0	1.4	-0.5
Fractured/broken bones in last 5 years	0.5	0.7	3.9	0.7	0.8	2.0	-0.9	-0.4	0.2	1.1	0.0	1.0	-0.9	0.7	1.2	0.2	-0.0	0.2	0.6	-0.3	1.1
Age started oral contraceptive pill	0.5	0.6	3.4	0.6	0.9	0.2	1.8	0.7	0.6	0.6	-0.2	0.1	0.2	0.4	0.4	0.4	-1.6	0.1	0.5	-1.2	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.6	0.4	0.8	0.9	-0.3	-0.9	-0.4	0.8	0.0	0.3	-1.5	-0.7	0.1	0.1	-1.3	-0.4	0.3	-1.6	-0.1
Depressed Affect (Nagel 2018)	0.4	0.9	3.1	-0.6	-0.8	-0.6	-0.9	0.5	-0.5	-0.5	-0.8	-1.3	-1.8	-1.5	-0.6	-0.3	0.6	0.7	-0.5	1.2	-1.5
Neuroticism (Nagel 2018)	0.4	0.9	2.2	-0.9	-1.2	-1.0	-1.1	-0.1	-0.9	-1.0	-0.9	-1.4	-1.4	-1.3	-0.8	-0.6	0.3	-0.1	-0.8	0.4	-1.5
Age at First Birth	0.4	0.6	1.7	-0.9	-1.0	-0.6	0.2	-0.9	-0.8	-0.8	-0.6	-0.4	0.5	-0.0	-1.1	-1.1	-0.1	-1.3	-0.9	-0.6	-0.3
LDL Cholesterol	0.4	0.7	2.7	-0.7	-0.5	-1.5	0.1	-0.8	-0.6	-0.8	-0.0	-0.3	-1.5	-0.6	-0.4	-0.5	-0.8	-1.6	-0.8	-0.7	-0.1
Height	0.4	8.5	15.9	3.4	3.6	3.6	3.0	1.6	2.7	3.6	3.0	4.0	3.1	1.9	2.2	3.6	0.8	1.6	3.2	0.9	3.5
Hypothyroidism (self reported)	0.4	0.9	3.1	0.1	0.4	1.8	-0.5	-1.6	-0.8	0.8	-0.6	0.3	0.5	1.2	0.3	-0.6	-1.4	-1.2	0.1	-1.6	0.0
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.7	0.8	0.8	0.7	0.5	0.3	0.5	0.8	1.1	0.7	0.7	1.1	1.0	0.7	1.3	1.1	0.8	1.2	0.9
Lung FEV1/FVC ratio	0.4	2.1	4.5	-1.7	-1.8	-1.5	-0.1	-1.3	-1.7	-1.7	-1.4	-1.9	-1.7	-0.6	-1.0	-2.1	0.4	-1.4	-1.8	0.3	-1.6
Lung FVC	0.4	1.9	3.4	1.8	1.6	1.4	0.4	1.4	1.8	1.8	1.1	1.9	0.5	1.3	1.4	1.3	0.4	0.5	1.8	1.2	1.7
Impedance of leg (right)	0.4	1.8	7.1	0.7	0.6	0.5	2.7	1.2	0.8	0.7	0.9	0.8	1.0	0.7	0.6	0.9	2.0	2.6	0.8	2.3	1.2
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	0.7	0.9	0.6	-0.6	1.0	0.6	0.7	0.7	0.4	-0.0	0.6	1.1	0.8	0.0	0.6	0.7	0.5	-0.1
Serious illness, injury or assault to yourself	0.4	0.5	1.4	-0.6	-0.9	-0.7	0.3	-0.3	-0.7	-1.2	-0.7	-0.8	0.0	-0.5	-0.8	-1.0	0.8	-0.7	-0.5	0.4	-0.9
Medication: Atenolol	0.4	0.5	4.2	0.3	0.4	0.2	2.0	0.7	0.6	0.7	0.8	0.0	0.0	-0.5	0.5	0.3	-0.6	0.9	0.4	-0.0	-0.2
Impedance of leg (left)	0.4	2.1	9.3	0.7	0.6	0.7	3.0	1.1	0.9	0.8	1.0	0.8	1.5	0.7	0.6	0.9	2.5	2.3	0.9	2.4	1.2
Fluid intelligence score	0.4	0.8	2.8	-0.6	-0.9	-0.3	-1.6	-1.1	-0.8	-0.4	-0.3	-0.6	-0.9	1.2	0.4	-0.9	-0.7	-1.7	-0.7	-1.1	-0.7
Neuroticism score	0.4	0.7	2.8	-0.6	-0.9	-0.0	-1.5	-0.7	-0.8	-0.4	-0.8	-0.9	-1.7	-0.9	-0.2	-0.7	-0.4	-0.6	-0.6	-1.0	-1.1
Father’s age at death	0.4	0.5	3.0	0.2	0.5	0.3	0.7	0.1	0.3	0.2	-0.3	0.6	1.4	1.7	0.6	0.3	0.8	-0.2	0.2	0.4	1.2
Exposure to tobacco smoke at home	0.4	0.4	1.4	-0.2	-0.7	-0.8	1.2	0.5	0.0	-0.7	0.1	-0.4	0.3	-0.9	-0.7	0.8	0.8	0.3	-0.2	0.9	-0.4
Peak expiratory flow (PEF)	0.4	1.0	4.4	0.5	0.2	2.1	-1.9	-0.8	-0.0	1.0	-0.3	0.7	-1.3	0.3	0.6	-0.6	-0.6	-1.7	0.5	-0.9	0.5
Leg fat percentage (right)	0.4	1.3	3.2	-1.1	-0.8	-0.2	-1.2	-1.6	-1.5	-1.0	-0.9	-0.9	-1.8	-1.4	-1.5	-1.1	-0.5	0.2	-1.1	-1.4	-1.1
Qualifications: College or University degree	0.4	1.2	3.7	0.3	0.3	-0.3	0.3	0.0	0.4	0.3	1.7	0.8	1.9	1.8	0.9	0.9	1.6	-0.1	0.3	1.7	1.7
Medication for pain relief, constipation, heartburn	0.4	0.7	2.9	0.5	0.6	-0.1	0.1	1.5	0.9	0.0	0.2	0.2	1.3	0.1	0.0	0.9	1.7	0.6	0.5	1.7	0.2
Had major operations	0.4	0.4	1.7	0.4	-0.1	1.3	0.1	-0.2	0.2	0.8	0.2	0.6	0.1	1.3	1.1	-0.1	0.4	-0.8	0.5	-0.7	0.5
Supplements: Vitamin C	0.4	0.5	1.2	-0.7	-0.7	-0.9	0.6	-1.1	-1.0	-1.0	0.1	-0.6	-0.5	0.2	-0.5	-0.2	0.8	-0.9	-0.8	0.4	-0.4
Smoking status: Previous	0.4	0.5	1.6	0.8	0.9	1.3	-0.7	0.2	0.4	0.9	0.4	0.5	-1.2	0.6	1.1	-0.0	-0.0	0.0	0.8	-0.9	-0.2
Arm fat percentage (left)	0.4	1.7	5.0	-1.1	-0.6	0.2	-1.8	-1.9	-1.6	-0.7	-1.0	-0.9	-1.6	-0.9	-1.1	-1.2	-1.6	-0.9	-1.1	-2.2	-1.2
Average weekly red wine intake	0.4	0.6	1.4	-1.1	-0.8	-0.9	-0.5	-0.9	-1.0	-0.8	-0.7	-0.8	-0.5	-0.7	-1.0	-1.2	-0.4	-0.1	-1.0	0.3	-0.3
Diabetes diagnosed by doctor	0.4	0.7	2.2	0.7	0.9	0.5	0.3	0.8	0.7	0.7	0.7	0.4	0.8	1.3	1.0	0.5	0.8	1.5	0.8	1.0	0.4
Medication: Gliclazide	0.4	0.4	1.0	-0.5	-0.3	-0.9	-0.8	-1.0	-0.8	-0.6	-0.3	-0.5	-0.8	-0.1	-0.4	-0.8	-0.9	-0.2	-0.5	-0.5	-0.3
Miserableness	0.4	0.6	3.6	0.4	-0.1	0.6	-1.9	0.7	0.2	0.4	-0.1	-0.2	-1.4	-0.4	0.6	0.5	0.8	1.1	0.5	1.0	-0.6
Wears glasses or contact lenses	0.4	0.5	3.3	0.2	0.2	0.1	0.8	0.7	0.5	0.3	0.4	0.3	1.8	-0.1	-0.0	0.1	0.1	1.5	0.3	0.5	0.6
Medication: Lisinopril	0.4	0.5	2.3	-0.4	-0.4	-1.5	0.5	1.0	0.2	-0.9	-0.1	-0.7	0.6	-0.4	-0.9	0.4	0.7	0.4	-0.4	1.3	-0.7
Unable to work because of sickness or disability	0.4	0.6	2.4	0.4	0.1	-0.4	-0.3	1.3	0.6	-0.0	-0.0	-0.0	-0.4	-0.5	0.4	0.6	1.6	1.3	0.5	1.6	-0.1
Myopia	0.4	0.6	2.4	0.4	0.1	-0.6	-0.1	0.5	0.6	-0.4	0.9	0.3	1.2	1.6	0.8	0.3	1.5	-0.8	0.4	0.3	-0.0
Impedance of whole body	0.4	1.8	5.2	1.1	1.3	1.3	2.3	1.2	1.0	1.3	0.9	1.1	1.1	0.8	1.1	1.2	1.4	1.9	1.3	1.7	1.3
Depression (Nagel 2018)	0.3	0.4	1.2	0.7	0.7	0.6	-0.3	0.8	0.5	0.7	0.4	0.2	-1.1	-0.9	0.4	0.7	0.9	0.5	0.7	0.8	-0.2
Triglycerides	0.3	0.5	1.2	-0.6	-0.4	0.8	-1.0	-1.0	-1.1	-0.1	-0.4	-0.4	-0.6	-0.4	-0.7	-1.1	-0.5	0.7	-0.6	-0.2	-0.2
Smoking Status	0.3	0.7	2.8	-0.5	-0.6	-1.2	-1.3	1.1	0.2	-0.5	0.3	-0.8	-1.0	0.0	0.3	-0.4	1.5	0.9	-0.3	1.7	-0.4
Hearing difficulty/problems: Yes	0.3	0.4	2.2	-0.1	-0.1	0.3	0.7	-1.0	-0.5	0.0	-0.1	-0.2	-0.7	-0.4	0.1	-0.3	-1.1	-0.9	-0.1	-1.5	-0.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	1.9	0.3	0.2	0.5	0.5	-0.6	-0.1	0.4	0.1	0.2	0.6	-0.3	0.2	-0.1	-0.9	-1.2	0.3	-1.4	-0.1
Medication for hormone replacement therapy	0.3	0.3	1.4	-0.1	-0.2	0.7	-1.1	-0.3	-0.2	0.2	-0.5	-0.0	-0.2	-0.6	-0.5	-0.3	-0.5	1.1	-0.1	-1.2	-0.3
Diabetes (father)	0.3	0.4	1.8	-0.1	-0.4	0.6	-0.2	-1.3	-0.6	-0.0	-0.2	0.4	0.1	1.2	0.3	-0.6	0.8	-1.3	-0.2	0.2	0.9
Relative age voice broke	0.3	0.5	1.2	-0.7	-0.9	-0.8	-1.1	-0.6	-0.7	-0.8	-0.5	-0.9	-1.0	-0.6	-0.2	-0.7	0.2	0.4	-0.7	-0.1	-1.1
Taking other prescription medications	0.3	0.5	2.5	0.3	0.8	1.4	0.6	-0.8	-0.4	0.8	-0.2	0.1	0.3	0.4	0.8	0.1	-0.9	-0.3	0.3	-1.6	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.3	-0.5	-0.0	0.5	-0.8	-1.2	-1.0	-0.1	-1.0	-0.5	-1.1	-0.3	-0.6	-1.0	-1.5	-0.6	-0.6	-1.2	-0.9
Qualifications: CSEs or equivalent	0.3	0.4	0.9	0.9	0.8	0.9	-0.7	0.9	0.8	0.6	0.1	0.6	-0.3	0.1	0.5	0.6	0.3	0.1	0.8	-0.1	-0.1
High blood pressure	0.3	0.7	3.2	-0.5	-0.6	-1.6	0.7	0.7	0.0	-0.8	0.5	-0.7	0.1	-0.9	-0.6	-0.2	0.8	1.8	-0.4	1.5	-0.3
Stomach or abdominal pain in last month	0.3	0.3	1.8	-0.2	0.1	0.6	-1.4	-0.5	-0.3	0.2	-0.3	-0.2	-0.3	-0.5	-0.3	-0.5	-1.1	0.4	-0.2	-0.8	-0.1
Alcohol usually taken with meals	0.3	0.4	1.6	-0.4	0.1	0.6	0.9	-1.2	-0.8	0.1	-0.6	0.0	-0.2	0.6	-0.1	-0.6	-1.1	-0.5	-0.4	-1.3	-0.0
Nervous feelings	0.3	0.5	1.8	-0.4	-0.7	0.1	-0.4	-0.9	-0.9	-0.3	-0.8	-0.7	-0.7	0.1	-0.4	-0.2	-1.2	-0.7	-0.4	-1.3	-1.3
Allergy	0.3	0.7	1.9	0.6	0.3	0.1	1.4	1.3	1.0	0.4	0.9	0.8	0.2	0.4	0.2	0.6	0.8	0.9	0.5	1.2	1.4
Alcohol intake versus 10 years previously	0.3	0.4	1.1	-0.7	-0.8	-0.8	0.4	-1.0	-0.7	-0.7	-0.1	-0.3	-0.1	-0.7	-0.7	0.3	-0.5	-1.0	-0.7	-0.3	0.0
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.9	1.1	0.8	1.6	0.1	-0.1	0.7	1.4	0.9	1.6	0.1	0.5	0.9	0.7	-0.3	-1.0	1.0	0.1	1.7
Qualifications: A levels/AS levels or equivalent	0.3	0.7	7.8	-0.2	0.0	0.2	-2.8	-1.3	-0.7	0.1	0.6	0.1	-0.4	1.0	0.3	-0.2	-0.4	-0.7	-0.2	-0.6	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.2	-0.4	-0.5	0.2	-0.1	-1.1	-0.5	-0.0	-0.3	0.2	-1.0	0.5	0.1	-0.8	-1.0	-0.6	-0.4	-0.9	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.7	1.3	1.0	1.3	-0.5	0.0	0.9	1.4	1.1	1.6	0.2	0.7	1.0	0.9	-0.8	-1.3	1.2	-0.5	1.6
Arm fat mass (right)	0.3	1.4	4.9	-0.8	-0.4	0.3	-1.5	-1.9	-1.4	-0.4	-0.7	-0.5	-1.3	-0.9	-1.0	-1.0	-1.6	-1.0	-0.8	-2.2	-0.8
Length of working week for main job	0.3	0.4	2.4	0.1	-0.0	-1.0	1.6	0.6	0.5	-0.3	0.1	-0.0	-0.6	-0.0	0.2	0.7	0.9	0.1	0.0	1.0	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	4.2	-0.2	-0.1	0.4	-2.0	-0.3	-0.4	-0.1	-0.5	-0.6	-1.2	-0.2	0.2	-0.2	-0.4	0.0	-0.1	-0.8	-1.1
Medication: Ventolin 100micrograms inhaler	0.3	0.4	2.8	0.1	0.6	0.3	-0.4	-0.8	-0.2	0.2	-0.1	0.2	-0.3	0.2	0.3	-0.3	-1.1	-1.7	-0.1	-1.5	-0.0
Body fat percentage	0.3	1.0	2.5	-0.9	-0.5	0.4	-1.1	-1.6	-1.4	-0.6	-0.8	-0.7	-1.3	-1.2	-1.2	-0.9	-0.8	-0.3	-0.8	-1.4	-1.0
Worry too long after embarrassment	0.3	0.5	2.7	-0.6	-0.8	-1.6	1.3	0.5	-0.1	-1.0	-0.2	-0.7	0.0	-0.5	-0.6	-0.3	0.1	-0.1	-0.6	0.4	-0.5
Medication: Blood pressure	0.3	0.5	2.6	0.3	0.3	-0.4	0.1	1.0	0.7	0.1	0.9	0.1	0.9	0.7	0.5	0.5	0.7	1.6	0.3	1.3	0.3
Medication: Ibuprofen	0.3	0.3	1.4	-0.0	0.2	0.3	0.5	-0.8	-0.2	0.5	0.3	0.4	-0.9	0.2	0.3	-0.4	-1.2	-0.7	-0.1	-0.8	0.6
Leg fat mass (right)	0.3	1.0	2.8	-0.9	-0.6	-0.0	-1.2	-1.7	-1.4	-0.8	-0.6	-0.6	-1.3	-1.1	-1.2	-0.9	-0.6	-0.5	-0.9	-1.4	-0.9
Age at last live birth	0.3	0.4	4.5	-0.0	0.1	0.3	-2.1	-0.2	-0.1	0.4	0.6	0.1	0.5	0.7	0.4	-0.7	0.3	-0.5	-0.1	0.3	0.3
Knee pain experienced in last month	0.3	0.5	1.9	-0.1	0.1	-0.9	-0.1	0.4	-0.1	-0.8	-0.7	-0.7	-1.0	-1.0	-0.5	-0.1	0.8	-1.1	-0.2	0.0	-1.4
Hypertension (Self-reported)	0.3	0.8	3.4	-0.8	-0.8	-1.9	0.8	0.6	-0.1	-1.0	0.2	-1.0	-0.0	-0.8	-0.8	-0.3	0.6	1.4	-0.6	1.4	-0.7
Illnesses of father: Heart disease	0.3	0.4	2.8	0.3	-0.1	0.9	-0.7	-0.2	-0.0	0.4	-0.5	0.1	-1.7	-0.6	-0.3	0.1	-0.8	-0.7	0.4	-1.1	-0.5
Mood swings	0.3	0.5	3.2	-0.2	-0.6	-0.3	-1.0	0.6	-0.0	-0.2	-0.2	-0.7	-0.9	-0.5	0.0	0.2	1.4	0.8	-0.2	1.8	-0.4
Long-standing illness, disability or infirmity	0.3	0.5	1.4	-0.6	-0.5	-0.4	-0.6	-0.6	-0.7	-1.0	-0.8	-0.9	0.1	0.1	-0.2	-1.2	0.0	-0.9	-0.6	-1.0	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	1.5	-0.2	-0.5	-0.7	0.1	0.2	-0.3	-0.3	-0.9	-0.8	-0.9	-1.2	-0.4	-0.4	-0.4	-0.7	-0.3	-0.6	-1.2
Arm fat mass (left)	0.3	1.4	4.7	-0.8	-0.5	0.3	-1.7	-2.0	-1.4	-0.5	-0.6	-0.5	-1.3	-0.7	-0.9	-1.0	-1.5	-1.1	-0.9	-2.2	-0.8
Number of self-reported non-cancer illnesses	0.3	0.5	2.1	-0.7	-0.5	-0.2	-1.0	-0.8	-0.9	-0.6	-0.5	-1.2	0.2	-0.5	-0.3	-0.9	0.1	-0.6	-0.6	-0.8	-1.4
Guilty feelings	0.3	0.5	2.8	-0.4	-0.3	0.4	-0.2	-0.5	-0.7	-0.3	-0.8	-0.5	-0.7	-0.5	-0.0	-0.7	-1.0	-0.8	-0.3	-1.7	-1.1
Eye problems/disorders: Glaucoma	0.3	0.3	1.2	0.4	0.7	1.0	-0.2	-0.4	0.1	1.1	0.5	0.5	0.2	-0.4	0.1	0.1	-0.7	0.6	0.4	-0.5	0.7
Ever smoked	0.3	0.6	1.6	0.5	0.8	-0.4	0.1	1.3	1.0	0.3	1.0	0.4	0.7	0.9	0.6	0.6	0.9	1.0	0.6	1.0	0.5
Leg fat percentage (left)	0.3	1.2	2.6	-1.0	-0.8	-0.1	-1.1	-1.6	-1.5	-0.9	-0.8	-0.9	-1.5	-1.5	-1.5	-1.1	-0.4	-0.1	-1.1	-1.4	-1.1
Pain experienced in last month	0.3	0.6	1.3	-1.0	-0.9	-0.7	1.0	-0.9	-0.7	-0.7	-0.8	-0.3	0.2	0.1	-0.7	-1.1	-1.1	-0.8	-1.0	-0.3	0.2
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.2	0.8	0.6	1.0	-0.3	0.3	0.7	0.9	1.1	1.0	1.2	1.5	1.0	1.0	0.2	0.2	0.8	0.0	0.9
Worry (Nagel 2018)	0.2	0.5	1.4	-0.7	-0.9	-0.6	-1.2	-0.3	-0.7	-0.8	-0.6	-1.0	-0.6	-0.7	-0.6	-0.2	-0.0	-0.1	-0.7	-0.3	-1.1
Alzheimer’s Disease (in mother)	0.2	0.2	0.8	0.5	0.1	0.5	-0.9	0.3	0.3	0.2	0.2	0.5	-0.1	0.1	-0.3	0.8	0.7	0.1	0.4	0.6	0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	2.1	-0.4	-0.5	0.1	-1.4	-0.9	-0.7	-0.1	-0.2	-0.2	-0.5	-0.4	-0.7	0.1	-0.0	-0.8	-0.4	0.4	0.4
Ovarian Cancer	0.2	0.2	1.0	-0.2	-0.3	-0.4	-0.6	0.0	-0.2	-0.4	-0.4	-0.2	-0.9	-1.0	-0.4	-0.4	-0.7	0.5	-0.2	-0.1	-0.2
Crohns Disease (2012)	0.2	0.3	1.3	-0.3	-0.5	-0.7	0.7	0.7	0.3	-0.3	0.1	-0.1	0.2	0.0	-0.3	-0.2	0.6	0.8	-0.2	1.1	0.7
Primary Biliary Cirrhosis	0.2	0.3	1.5	-0.0	0.5	-0.5	0.4	0.5	0.3	0.0	0.1	-0.0	0.1	-0.3	-0.1	0.7	0.8	1.2	0.0	1.0	0.5
BMI	0.2	0.9	3.9	-0.3	0.0	1.3	-1.2	-1.7	-1.1	0.3	0.1	-0.0	-1.5	-0.3	-0.3	-0.5	-1.5	-0.3	-0.3	-2.0	-0.3
Cardiovascular Disease	0.2	0.7	3.5	0.0	-0.2	-0.9	1.0	0.9	0.4	-0.3	0.9	-0.1	0.2	-0.3	-0.2	0.8	1.2	1.7	0.2	1.9	0.4
Respiratory disease	0.2	0.4	2.1	0.1	0.7	0.6	-1.3	-1.0	-0.3	0.3	0.4	0.1	-0.2	-0.2	0.2	-0.5	-0.6	-1.1	0.0	-1.4	-0.1
Neuroticism	0.2	0.5	2.8	-0.4	-0.6	-0.1	-1.0	-0.2	-0.6	-0.2	-0.6	-0.9	-1.7	-0.9	-0.0	-0.3	-0.4	-0.2	-0.4	-0.7	-1.1
Tanning	0.2	2.9	4.7	-1.9	-2.1	-1.3	-1.4	-1.9	-1.9	-2.0	-2.2	-1.7	-1.0	-0.5	-1.8	-1.8	-1.1	-2.1	-1.9	-1.6	-2.0
Average weekly spirits intake	0.2	0.2	1.7	0.0	-0.1	0.4	0.3	-0.1	0.0	-0.0	0.0	0.5	1.3	0.3	-0.2	-0.4	0.0	1.1	0.2	-0.1	0.6
Systolic blood pressure, automated reading	0.2	0.7	4.8	-0.4	-0.3	-0.9	0.4	0.9	0.0	-0.7	-0.3	-0.7	-0.3	-0.3	-0.6	-0.3	1.2	2.2	-0.2	1.3	-0.5
Medication: Co-codamol	0.2	0.3	1.7	0.2	0.2	0.3	1.3	-0.5	0.1	0.3	-0.1	0.4	0.5	-0.6	-0.2	0.8	0.0	0.2	0.1	-0.1	0.9
Diabetes (mother)	0.2	0.2	1.5	0.1	0.4	-0.3	-0.1	0.0	0.1	0.0	-0.1	-0.3	-1.2	-0.6	0.1	0.3	-0.2	-0.9	-0.1	-0.4	-0.7
Trunk fat percentage	0.2	0.6	2.2	-0.5	0.0	0.8	-0.9	-1.5	-1.1	-0.0	-0.4	-0.3	-1.0	-0.8	-0.8	-0.5	-0.9	-0.5	-0.4	-1.5	-0.5
Townsend deprivation index at recruitment	0.2	0.3	3.3	-0.3	-0.3	-0.2	1.8	-0.5	-0.4	-0.2	0.3	-0.2	-0.0	-0.6	-0.0	-0.1	-0.0	0.5	-0.3	0.4	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.4	0.4	0.4	0.4	-1.2	0.3	0.3	0.2	-0.1	0.2	-0.7	-0.3	0.2	0.7	0.8	-0.1	0.3	0.4	0.1
Age when periods started (menarche)	0.2	0.4	1.0	0.6	0.5	1.0	-0.6	-0.3	0.1	0.5	0.9	0.8	0.6	0.4	0.6	0.9	0.6	1.0	0.4	0.2	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.4	-0.7	-0.5	0.2	-0.6	-1.1	-1.0	-0.3	-1.2	-0.7	0.3	-0.4	-0.1	-0.8	-0.8	-0.6	-0.6	-0.7	-0.8
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.1	0.0	-0.3	0.0	-0.9	-0.1	-0.2	0.0	-0.0	-0.2	-0.7	-0.4	-0.0	-0.1	-1.0	0.3	0.0	-0.8	-0.7
High blood pressure (mother)	0.2	0.3	0.9	0.7	0.4	0.3	0.9	0.5	0.5	0.5	0.3	0.5	0.2	0.7	0.8	0.5	0.7	-0.3	0.7	0.3	0.3
Waist circumference	0.2	0.6	2.3	-0.7	-0.5	0.1	-1.0	-1.5	-1.2	-0.5	-0.2	-0.4	-0.6	-0.8	-0.9	-0.6	-0.5	-0.4	-0.7	-1.2	-0.5
Past tobacco smoking	0.2	0.3	0.9	-0.6	-0.7	-0.4	0.8	-0.7	-0.6	-0.6	-0.7	-0.2	0.8	-0.5	-0.9	-0.0	-0.4	-0.4	-0.6	-0.1	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.1	-0.3	0.1	0.4	-1.1	-0.8	-0.7	-0.2	-0.8	-0.4	-1.0	0.1	-0.3	-0.7	-0.9	-0.2	-0.5	-0.7	-0.8
Qualifications: None of the above	0.2	0.4	2.3	0.1	0.1	0.5	1.5	0.5	0.3	-0.0	-0.6	0.1	0.0	-0.6	0.1	0.3	1.0	1.4	0.1	0.6	0.0
Impedance of arm (right)	0.2	1.0	2.2	0.9	1.2	1.0	1.5	1.1	0.8	1.0	0.5	0.7	0.7	0.8	1.1	1.1	0.3	1.4	1.0	1.1	0.7
Trunk fat-free mass	0.2	1.2	2.9	1.2	1.2	1.2	-0.4	-0.1	0.9	1.4	1.7	1.7	1.1	0.9	1.0	1.2	-0.4	-0.3	1.1	-0.7	1.4
Worrier / anxious feelings	0.2	0.3	1.2	-0.6	-0.3	-0.6	-0.1	-0.2	-0.5	-0.5	-0.6	-0.7	-0.2	-1.1	-0.7	-0.6	-0.5	-0.1	-0.5	-0.2	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	1.0	0.5	0.3	-0.3	0.1	0.8	0.6	0.4	0.9	0.2	-0.0	-0.4	0.6	1.0	0.8	1.0	0.6	0.8	0.5
Falls in the last year	0.2	0.2	0.7	0.3	0.4	0.8	-0.6	-0.1	0.0	0.6	0.1	0.0	-0.7	-0.5	0.2	0.4	-0.6	-0.3	0.3	-0.7	-0.5
Impedance of arm (left)	0.2	1.0	1.7	0.9	1.3	0.8	1.3	1.2	1.0	1.0	0.7	0.8	0.8	1.0	1.2	1.1	0.3	1.3	1.1	0.9	0.8
Trunk predicted mass	0.2	1.2	3.0	1.2	1.2	1.3	-0.4	-0.1	0.9	1.4	1.7	1.7	1.1	0.9	1.0	1.2	-0.4	-0.3	1.1	-0.7	1.4
Breastfed as a baby	0.2	0.3	0.8	0.6	0.4	0.8	0.5	0.9	0.8	0.6	0.1	0.2	0.8	0.2	0.3	0.3	0.2	0.5	0.7	-0.8	-0.2
Hair/balding pattern: Pattern 4	0.2	0.4	1.6	0.5	0.1	1.3	-0.8	0.4	0.5	0.5	0.1	0.7	0.6	1.1	0.5	0.6	0.4	1.0	0.6	-0.1	0.8
Headache pain in last month	0.2	0.3	1.2	0.4	0.4	1.1	-0.3	-0.4	-0.1	1.0	0.2	0.2	-0.5	-0.3	0.5	0.3	-1.0	0.5	0.4	-0.3	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.7	-0.2	-0.5	-0.0	-0.2	-0.5	-0.3	-0.3	-0.9	-0.1	-0.7	-0.6	-0.5	-0.4	-0.4	-1.3	-0.2	-0.5	-0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	2.3	0.1	0.5	1.5	0.1	-0.9	-0.5	0.6	-0.4	0.3	1.0	0.8	0.4	-0.3	-0.8	-0.4	0.1	-1.0	-0.0
Number of children fathered	0.2	0.2	1.1	0.3	0.1	0.4	-0.1	-0.1	0.1	0.4	0.9	0.5	-0.1	-0.3	-0.2	0.2	1.1	0.4	0.1	0.5	0.7
Migraine (self-reported)	0.2	0.2	0.9	0.2	0.9	0.2	0.3	-0.1	-0.1	0.6	0.3	0.1	0.9	0.2	0.3	-0.3	-0.4	0.7	0.2	0.4	0.5
Whole body fat mass	0.2	0.6	2.4	-0.5	-0.1	0.6	-1.0	-1.6	-1.1	-0.1	-0.3	-0.3	-0.8	-0.9	-0.8	-0.5	-0.8	-0.6	-0.5	-1.5	-0.5
Overall health rating	0.2	0.4	2.7	-0.0	-0.1	0.2	-0.2	0.2	0.0	0.0	0.1	-0.1	-1.2	-1.2	0.1	0.1	0.9	1.6	0.1	1.0	0.3
Chest pain or discomfort	0.2	0.3	3.5	-0.3	-0.3	0.2	-1.9	-0.4	-0.2	-0.2	0.2	-0.1	0.1	-0.4	0.1	-0.7	-0.4	-0.6	-0.3	-0.8	0.2
Medication: Aspirin	0.2	0.3	1.8	0.4	0.4	-0.4	1.4	0.4	0.5	0.4	0.7	0.4	0.1	0.2	0.4	0.5	-0.4	0.2	0.4	-0.3	0.4
Whole body fat-free mass	0.2	0.9	2.0	1.0	1.0	1.1	-0.8	-0.3	0.7	1.1	1.4	1.4	0.7	0.7	0.8	1.0	-0.5	-0.8	0.9	-0.8	1.1
Commuting to job workplace: Walk	0.2	0.2	1.8	-0.2	-0.2	-0.2	-0.6	-0.6	-0.2	-0.3	0.4	-0.0	0.1	0.2	0.2	-0.6	-0.4	-1.4	-0.3	-0.6	0.1
Osteoporosis (self-reported)	0.2	0.2	0.8	-0.5	-0.3	-0.2	0.3	-0.2	-0.5	-0.3	-0.2	-0.6	-0.9	-0.1	-0.1	-0.0	-0.2	0.7	-0.4	-0.5	-0.6
Medication: Aspirin	0.2	0.3	1.8	0.5	0.4	-0.0	1.3	0.4	0.5	0.5	0.7	0.5	-0.1	0.3	0.4	0.8	-0.3	0.2	0.5	-0.2	0.3
Tinnitus: Yes, now most or all of the time	0.2	0.3	0.6	0.7	0.2	0.8	-0.8	0.3	0.5	0.7	0.0	0.5	-0.7	-0.7	-0.3	0.8	-0.3	-0.3	0.6	-0.5	0.0
Alcohol drinker status: Never	0.2	0.2	1.0	0.1	-0.0	-0.4	-0.8	0.2	0.0	-0.0	0.1	-0.4	-1.0	-0.1	0.4	0.4	-0.4	-1.0	0.0	-0.4	-0.8
Risk taking	0.2	0.3	0.8	-0.4	-0.4	-0.3	-0.9	-0.8	-0.5	-0.5	-0.5	-0.3	-0.6	-0.4	-0.3	0.1	-0.6	-0.7	-0.5	-0.7	-0.2
Diastolic blood pressure, automated reading	0.2	0.6	2.7	-0.8	-0.9	-0.8	-1.6	-0.3	-0.6	-0.7	0.1	-0.8	-1.4	-0.2	-0.3	-1.2	0.4	0.6	-0.7	0.3	-0.3
Commuting to job workplace: Cycle	0.2	0.2	0.8	-0.8	-0.2	-0.9	-0.2	-0.2	-0.4	-0.4	0.1	-0.8	0.3	0.4	-0.2	-0.7	-0.4	-0.2	-0.8	0.1	-0.2
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.4	0.5	0.7	1.6	-0.5	-0.5	0.1	0.9	-0.4	0.7	0.2	0.9	0.6	0.0	-0.7	-1.4	0.4	-1.0	0.4
Alcohol drinker status: Previous	0.2	0.2	1.2	-0.3	-0.3	0.2	0.5	0.3	0.1	-0.1	0.1	-0.2	0.7	-0.2	0.1	0.2	0.8	1.1	-0.2	0.5	0.1
Leg fat mass (left)	0.2	0.9	2.5	-0.9	-0.6	-0.0	-1.1	-1.6	-1.3	-0.8	-0.5	-0.6	-1.1	-1.2	-1.3	-0.8	-0.5	-0.5	-0.9	-1.4	-0.9
Bipolar Disorder or Schizophrenia	0.1	0.3	1.7	0.3	0.1	0.5	-1.3	-0.2	0.2	0.6	0.5	0.2	-0.6	0.4	0.1	1.0	-0.1	-0.1	0.3	-0.4	-0.2
Reaction Time	0.1	0.2	0.5	-0.3	-0.3	-0.6	-0.6	-0.1	-0.0	-0.3	-0.4	-0.3	0.1	-0.3	-0.5	-0.0	-0.7	-0.3	-0.2	-0.7	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.1	-0.6	-0.8	-0.5	-0.2	-0.9	-0.8	-0.4	-0.1	-0.4	0.4	1.1	-0.1	-0.3	-0.5	-0.8	-0.6	-0.3	-0.3
Breast Cancer	0.1	0.1	0.7	0.3	0.2	0.8	-0.8	-0.4	-0.0	0.3	-0.0	0.3	0.1	0.2	0.2	-0.1	0.1	0.2	0.3	0.1	0.6
Bipolar Disorder (2011)	0.1	0.1	1.5	0.0	-0.2	0.6	-0.1	-1.2	0.0	0.0	-0.4	0.0	-0.5	0.1	-0.1	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.1	0.2	0.4	-0.4	-0.3	-0.6	-0.6	-0.2	-0.4	-0.5	-0.0	-0.4	-0.3	0.4	-0.6	-0.5	0.5	-0.0	-0.4	0.2	-0.3
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.4	0.0	0.5	-0.1	0.0	0.3	0.2	0.3	0.0	0.0	0.5	-0.1	0.0	0.5	-0.6	0.1	0.4	0.4	0.2
Heel T-Score	0.1	0.4	3.8	-0.1	-0.0	0.6	-1.9	-0.1	-0.2	-0.3	-1.1	-0.2	-0.5	-0.8	-1.1	0.4	-0.1	0.1	-0.2	0.1	-0.2
Allergy or Eczema	0.1	0.1	0.8	-0.3	-0.0	0.1	-0.6	-0.5	-0.4	-0.0	-0.5	-0.3	0.9	-0.1	0.1	-0.4	-0.2	-0.4	-0.2	-0.2	-0.4
Hair Pigment	0.1	3.4	7.2	2.0	1.9	1.3	2.7	1.7	1.9	1.7	1.9	2.1	1.7	1.5	1.3	2.4	1.3	1.9	2.0	1.3	1.8
Hand grip strength (left)	0.1	0.3	1.4	0.0	-0.1	0.8	-1.2	-0.6	-0.2	0.6	0.5	0.3	-0.6	0.3	0.1	-0.1	0.1	-0.3	-0.0	0.6	0.8
Relative age of first facial hair	0.1	0.2	0.8	-0.3	-0.3	-0.7	-0.3	0.4	0.2	-0.6	-0.2	-0.2	0.2	0.4	0.0	-0.8	0.6	0.9	-0.3	0.8	-0.2
Leg fat-free mass (left)	0.1	0.5	2.0	0.6	0.6	0.7	-1.4	-0.5	0.3	0.7	0.8	0.9	0.1	0.3	0.4	0.6	-0.9	-1.2	0.5	-1.0	0.5
Medication: Levothyroxine sodium	0.1	0.2	0.6	-0.3	0.0	0.7	0.6	-0.4	-0.5	0.2	-0.3	-0.3	0.6	0.3	0.3	-0.7	-0.6	-0.2	-0.2	-0.7	-0.4
Leg predicted mass (left)	0.1	0.6	2.0	0.7	0.7	0.7	-1.4	-0.4	0.4	0.8	0.9	1.0	0.1	0.3	0.5	0.7	-0.8	-1.2	0.6	-0.9	0.6
Trunk fat mass	0.1	0.5	2.2	-0.1	0.3	1.0	-0.9	-1.3	-0.7	0.3	0.1	0.2	-0.6	-0.5	-0.4	-0.1	-0.9	-0.5	-0.1	-1.5	-0.1
Number of incorrect matches in round	0.1	0.2	0.6	0.4	0.7	0.5	-0.7	0.6	0.3	0.3	-0.8	-0.2	-0.3	0.2	0.4	-0.6	-0.0	0.7	0.5	-0.3	-0.7
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.8	0.4	0.1	0.4	-0.9	0.2	0.3	0.4	0.7	0.2	0.4	0.1	0.5	0.4	0.5	-0.1	0.4	0.3	0.2
Weight	0.1	0.5	2.2	0.0	0.3	0.7	-1.0	-1.3	-0.5	0.3	0.4	0.4	-0.5	-0.5	-0.3	0.0	-0.9	-0.9	-0.1	-1.5	0.2
Hip circumference	0.1	0.5	2.3	-0.3	-0.1	0.2	-0.3	-1.2	-0.6	-0.3	0.2	0.0	-1.0	-1.4	-0.6	-0.1	-0.7	-0.8	-0.3	-1.5	-0.1
Hair/balding pattern: Pattern 3	0.1	0.2	1.1	-0.2	-0.1	-0.3	0.7	0.0	-0.1	-0.1	-0.7	-0.2	-0.6	0.1	-0.2	-0.2	-1.1	0.2	-0.1	-0.9	-0.2
Mouth/teeth dental problems: Dentures	0.1	0.1	0.5	-0.3	-0.3	-0.1	-0.4	0.3	0.1	-0.2	-0.7	-0.6	-0.4	-0.7	-0.0	-0.6	-0.1	0.1	-0.3	-0.2	-0.4
Illnesses of mother	0.1	0.2	0.7	-0.2	-0.2	-0.8	-0.1	0.4	0.3	-0.1	0.3	0.0	0.5	-0.2	-0.3	0.2	-0.2	0.8	-0.1	0.5	0.6
Tense / ‘highly strung’	0.1	0.1	1.0	-0.0	-0.5	0.1	-0.6	-0.1	-0.1	-0.3	0.2	-0.1	-0.1	0.4	0.2	0.2	1.0	-0.1	-0.1	0.5	-0.2
Birth weight of first child	0.1	0.1	1.2	-0.0	-0.1	0.4	-1.1	-0.2	-0.4	0.1	-0.2	-0.2	-0.5	-0.2	-0.2	0.2	-0.3	0.3	-0.0	0.6	-0.3
Loud music exposure frequency	0.1	0.1	0.7	0.0	0.0	-0.6	0.8	0.1	0.1	-0.2	-0.1	-0.1	-0.0	-0.4	-0.1	0.0	-0.5	-0.8	0.1	-0.2	-0.3
Arm fat-free mass (right)	0.1	0.5	1.6	0.9	0.8	0.6	-0.4	-0.1	0.7	0.8	1.3	1.2	0.7	0.4	0.5	0.8	-0.0	-0.8	0.7	-0.6	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.5	0.5	0.2	0.2	0.7	0.3	0.4	0.3	0.3	0.5	0.2	-0.2	-0.1	0.6	0.5	0.1	0.4	0.4	0.6
Health satisfaction	0.1	0.1	0.7	-0.1	-0.4	0.5	0.1	-0.2	-0.3	0.0	-0.1	-0.1	-0.6	-0.8	0.2	-0.1	0.7	0.2	0.0	0.2	0.1
Mean time to correctly identify matches	0.1	0.2	0.8	0.0	0.4	-0.2	-0.2	0.1	0.1	0.0	-0.5	-0.1	0.6	-0.5	-0.4	-0.0	-0.9	-0.3	0.1	-0.9	-0.2
Arm predicted mass (right)	0.1	0.5	1.2	0.7	0.6	0.7	-0.6	-0.5	0.4	0.8	1.1	1.1	0.7	0.5	0.5	0.6	-0.1	-1.0	0.5	-0.7	0.8
Alcohol intake frequency.	0.1	0.2	1.0	-0.1	-0.2	0.5	1.0	-0.7	-0.4	0.2	0.0	0.2	-0.3	-0.8	0.2	0.3	-0.0	-0.7	-0.1	-0.0	0.6
Suffer from ‘nerves’	0.1	0.2	0.9	0.1	-0.0	0.2	-0.9	0.2	0.2	0.1	0.1	0.1	-0.7	-0.3	0.4	0.4	0.3	0.9	0.2	0.1	0.3
Family relationship satisfaction	0.1	0.1	0.3	-0.0	-0.2	0.4	0.0	-0.1	-0.3	0.3	-0.5	-0.2	-0.6	-0.5	-0.1	-0.1	0.0	0.0	-0.0	0.2	-0.5
Leg fat-free mass (right)	0.1	0.6	2.3	0.7	0.6	0.8	-1.5	-0.5	0.3	0.7	0.9	1.0	0.2	0.3	0.5	0.6	-0.7	-1.5	0.5	-1.0	0.6
Illnesses of father: None of the above (group 1)	0.1	0.2	1.1	0.3	0.3	0.5	0.2	-0.2	0.2	0.5	0.5	0.7	0.1	0.1	-0.0	0.4	0.2	0.4	0.3	0.1	1.1
Whole body water mass	0.1	0.8	1.8	0.9	0.9	1.0	-0.8	-0.3	0.6	1.1	1.3	1.4	0.7	0.7	0.8	0.9	-0.6	-0.9	0.8	-0.9	1.0
Leg predicted mass (right)	0.1	0.6	2.5	0.6	0.5	0.7	-1.5	-0.6	0.2	0.7	0.9	0.9	0.2	0.3	0.4	0.6	-0.8	-1.6	0.4	-1.1	0.5
Basal metabolic rate	0.1	0.6	1.5	0.8	0.8	1.0	-1.0	-0.6	0.4	0.9	1.2	1.2	0.4	0.4	0.5	0.7	-0.6	-0.9	0.6	-0.9	0.9
Arm fat-free mass (left)	0.1	0.5	1.2	0.7	0.7	0.8	-0.5	-0.7	0.3	0.9	1.0	1.1	0.5	0.4	0.4	0.5	-0.5	-0.9	0.5	-1.0	0.8
Supplements: Calcium	0.1	0.2	1.6	-0.1	-0.1	0.0	-1.3	-0.1	-0.1	0.1	0.4	-0.1	-0.5	0.2	0.6	-0.0	-0.4	-0.0	-0.1	-0.3	-0.1
Basal cell carcinoma (self-reported)	0.1	0.1	0.4	-0.2	-0.5	-0.5	0.7	0.4	0.3	-0.2	-0.4	-0.1	-0.5	-0.5	0.0	-0.3	-0.4	-0.1	-0.2	-0.5	-0.2
Arm predicted mass (left)	0.1	0.6	1.4	0.8	0.8	1.0	-0.5	-0.6	0.4	1.0	1.1	1.2	0.5	0.4	0.5	0.6	-0.4	-1.0	0.7	-1.0	0.8
High cholesterol (Self-reported)	0.0	0.1	0.4	0.0	0.2	0.1	0.6	-0.4	-0.1	0.2	0.2	0.1	-0.5	-0.3	0.0	0.2	0.1	-0.1	0.1	0.0	0.3

Hub : Genes

SLFN12

Models

Trait associations