Hub : Genes

SLFN14

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 NTR Blood 0.0131 0.0057 0.0029 0.005 0.004 0.002 0.004 0.001 0.0061 0.014 0.056 0.012 0.20
2 TCGA Colon Adenocarcinoma 0.0470 0.0290 0.0091 0.010 0.021 0.006 NA 0.001 0.0790 0.022 0.140 NA 0.26

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.2 0.3 0.5 -0.4 0.7
Bipolar Disorder or Schizophrenia 0.5 1.1 2.2 1.5 -0.3
Depressed Affect (Nagel 2018) 3.8 7.9 10.0 -3.2 2.4
Depression (Nagel 2018) 5.1 7.6 9.9 -3.1 2.3
Intelligence (Savage-Jansen 2018) 1.2 3.8 7.3 2.7 -0.5
Neuroticism (Nagel 2018) 2.2 5.1 6.6 -2.6 1.9
Schizophrenia (2018) 1.4 2.9 4.9 2.2 -1.0
Schizophrenia vs Biploar Disorder 1.1 1.4 1.8 1.3 -1.0
Worry (Nagel 2018) 1.3 2.7 3.2 -1.8 1.5
Alzheimer’s Disease (in mother) 0.1 0.1 0.1 -0.3 -0.3
Alzheimer’s Disease (in father) 0.2 0.2 0.4 0.2 -0.6
Alzheimer’s Disease (including proxy) 0.1 0.1 0.2 -0.5 0.0
Crohns Disease (2017) 0.0 0.1 0.1 0.4 0.0
Irritable Bowel Disease (IBD) 0.3 0.7 1.3 1.1 -0.2
Ulcerative Colitis (UC) 0.6 1.2 2.1 1.5 -0.5
Major Depression (MDD) 0.9 1.1 1.6 -1.3 -0.8
Reaction Time 1.2 2.2 3.3 1.1 -1.8
Verbal and Numeric Reasoning (VNR) 2.5 5.9 10.5 3.2 -1.2
Breast Cancer 0.1 0.2 0.4 -0.6 0.1
Ovarian Cancer 0.1 0.2 0.3 0.2 -0.5
Prostate Cancer 1.2 1.7 2.9 -0.8 1.7
Age at First Birth 2.7 4.0 5.6 2.4 -1.5
Bipolar Disorder (2011) 0.3 0.3 0.6 0.8 0.0
Body Mass Index (BMI) (2010) 0.4 0.5 0.7 0.8 -0.6
Coronary Artery Disease (CAD) 0.9 1.1 1.4 0.9 -1.2
Crohns Disease (2012) 1.1 1.7 2.5 -0.9 1.6
Mean Putamen Volume 0.4 0.4 0.8 -0.3 -0.9
Fasting Glucose 0.2 0.3 0.4 -0.6 -0.4
HbA1C 0.4 0.4 0.5 0.6 -0.7
HDL Cholesterol 0.1 0.2 0.5 0.1 -0.7
LDL Cholesterol 1.3 2.0 2.4 -1.5 1.3
Lupus 0.1 0.2 0.2 0.5 -0.5
Neuroticism (2016) 3.7 5.4 8.1 -2.9 1.6
Primary Biliary Cirrhosis 0.6 0.8 1.3 -0.6 -1.1
Rheumatoid Arthritis 0.1 0.1 0.2 -0.0 0.4
Schizophrenia (2014) 1.2 2.7 3.2 1.8 -1.4
Triglycerides 0.8 1.4 1.4 -1.2 1.1
Type 2 Diabetes (T2D) (2012) 0.3 0.4 0.8 0.1 0.9
Ulcerative Colitis 0.3 0.4 0.6 0.8 -0.6
Blood Eosinophil Count 0.5 3.5 4.0 1.8 -2.0
Blood Platelet Count 7.1 82.3 102.0 7.9 -10.1
Blood Red Count 0.6 6.2 6.6 -2.4 2.6
Blood White Count 0.0 0.2 0.4 -0.3 -0.6
Heel T-Score 0.2 1.3 2.5 -1.6 0.3
BMI 0.9 5.1 7.3 -2.7 1.7
Height 0.1 2.8 4.4 2.1 -1.1
Waist Hip Ratio (WHR) 0.5 2.4 4.8 2.2 -0.3
Systolic Blood Pressure 0.3 1.7 2.8 -1.7 0.7
Smoking Status 2.3 5.5 6.4 -2.1 2.5
Allergy or Eczema 1.1 2.8 3.0 1.6 -1.7
Cardiovascular Disease 0.4 1.2 1.9 -1.4 0.7
Hypothyroidism (self reported) 1.6 3.7 6.2 2.5 -1.1
Respiratory disease 0.1 0.2 0.2 -0.5 0.5
Type 2 Diabetes (T2D) (2018) 0.2 0.3 0.6 -0.8 -0.2
Lung FEV1/FVC ratio 0.0 0.0 0.1 -0.1 -0.3
Lung FVC 0.1 0.6 1.1 0.2 1.0
Neuroticism 2.5 6.1 8.6 -2.9 1.9
Chronotype (morning person) 0.7 1.5 2.5 1.6 -0.8
Hair Pigment 0.0 0.5 0.8 -0.4 -0.9
Tanning 0.1 1.6 2.8 1.7 -0.6
Hand grip strength (left) 0.1 0.2 0.4 0.6 -0.1
Number of treatments/medications taken 1.0 1.7 2.3 -1.5 1.1
Average weekly spirits intake 0.2 0.2 0.4 0.6 0.1
Sensitivity / hurt feelings 0.9 1.6 3.1 -1.8 0.4
Frequency of depressed mood in last 2 weeks 7.6 10.6 13.1 -3.6 2.9
Hearing difficulty/problems: Yes 0.1 0.1 0.2 0.1 -0.5
Relative age of first facial hair 0.2 0.5 1.0 -0.0 1.0
Other serious medical condition/disability diagnosed by doctor 1.5 2.0 2.0 -1.4 1.4
Ever used hormone-replacement therapy (HRT) 1.9 2.5 3.2 1.3 -1.8
Ever had hysterectomy (womb removed) 2.9 3.2 5.8 0.8 -2.4
Systolic blood pressure, automated reading 0.7 2.0 3.9 -2.0 0.3
Eye problems/disorders: Diabetes related eye disease 0.5 0.5 1.0 1.0 0.2
Angina 0.4 0.6 1.1 -1.0 0.3
Medication for hormone replacement therapy 0.0 0.0 0.0 -0.0 0.2
Vitamin and mineral supplements 0.3 0.4 0.7 0.9 -0.2
Supplements: Zinc 1.6 1.7 2.5 -1.6 1.0
Medication: Co-codamol 2.4 2.8 3.8 -2.0 1.3
Medication: Metformin 0.1 0.2 0.2 0.5 -0.4
Diabetes (father) 0.3 0.4 0.5 -0.7 0.5
Diabetes (mother) 0.9 1.1 1.7 -1.3 0.8
Severe depression (siblings) 0.9 1.0 1.9 -0.1 1.4
Pack years adult smoking proportion 0.2 0.3 0.7 -0.8 -0.0
Impedance of leg (right) 0.9 4.5 5.3 2.3 -1.9
Leg fat-free mass (left) 0.4 2.1 2.4 -1.6 1.3
Trunk fat percentage 0.6 2.3 4.5 -2.1 0.4
Hand grip strength (right) 0.2 0.5 0.6 -0.6 0.8
Townsend deprivation index at recruitment 2.0 2.8 3.4 -1.5 1.9
Current tobacco smoking 0.3 0.4 0.8 -0.9 0.3
Average weekly fortified wine intake 0.1 0.1 0.3 0.5 -0.1
Maternal smoking around birth 0.3 0.5 0.9 -0.3 0.9
Fed-up feelings 4.2 7.6 10.7 -3.3 2.1
Frequency of unenthusiasm / disinterest in last 2 weeks 3.7 4.9 5.6 -2.4 2.1
Relative age voice broke 0.2 0.3 0.4 -0.5 0.6
Taking other prescription medications 3.2 4.9 6.4 -2.5 1.9
Age when periods started (menarche) 0.2 0.6 0.7 -0.9 0.7
Bilateral oophorectomy (both ovaries removed) 1.2 1.4 2.7 0.1 -1.6
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.3 -0.3 -1.1
Tinnitus: Yes, but not now, but have in the past 0.5 0.6 0.8 0.6 -0.9
Qualifications: CSEs or equivalent 0.4 0.5 0.9 -1.0 -0.4
Serious illness, injury or assault to yourself 3.9 4.8 6.2 -1.8 2.5
High blood pressure 0.4 1.2 2.1 -1.4 0.6
Hayfever, allergic rhinitis or eczema 0.4 0.9 0.9 0.9 -1.0
Multivitamins +/- minerals 1.5 2.0 3.0 -1.7 1.0
Stomach or abdominal pain in last month 0.1 0.1 0.1 -0.2 0.3
Supplements: Glucosamine 0.5 0.7 1.2 -1.1 0.5
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 0.9 0.8 -0.9
Medication: Atenolol 0.6 0.8 1.2 -1.1 0.6
Medication: Levothyroxine sodium 0.1 0.2 0.2 0.4 -0.4
Sitting height 0.5 3.2 6.2 2.5 -0.6
Chronic bronchitis/emphysema (father) 0.9 1.1 1.2 -1.0 1.1
High blood pressure (mother) 0.3 0.4 0.9 -0.9 -0.0
Body mass index (BMI) 1.2 5.0 8.6 -2.9 1.1
Impedance of leg (left) 0.8 4.1 5.3 2.3 -1.7
Leg predicted mass (left) 0.4 2.2 2.6 -1.6 1.3
Trunk fat mass 0.5 2.2 4.3 -2.1 0.4
Waist circumference 0.3 0.9 1.8 -1.3 0.1
Number of incorrect matches in round 1.8 3.0 3.3 1.6 -1.8
Past tobacco smoking 0.0 0.0 0.1 0.1 0.3
Alcohol usually taken with meals 8.1 13.1 16.2 4.0 -3.2
Nervous feelings 0.8 1.4 2.5 -0.6 1.6
Frequency of tenseness / restlessness in last 2 weeks 3.2 5.1 7.0 -2.6 1.8
Hearing difficulty/problems with background noise 1.0 1.5 2.3 -1.5 0.8
Hair/balding pattern: Pattern 2 1.6 2.0 3.0 1.0 -1.7
Had menopause 2.1 2.6 4.5 0.8 -2.1
Had other major operations 0.3 0.4 0.7 0.9 0.1
Forced vital capacity (FVC) 0.3 1.3 2.6 -0.1 1.6
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 1.6 -0.5 -1.3
Ever unenthusiastic/disinterested for a whole week 0.2 0.2 0.4 0.2 -0.6
Qualifications: None of the above 1.9 4.2 7.9 -2.8 0.7
Financial difficulties in last 2 years 0.7 1.0 1.7 -1.3 0.5
Mouth/teeth dental problems 0.7 1.1 1.8 1.4 -0.5
Heart attack 0.0 0.0 0.1 -0.2 0.2
Allergy 0.1 0.3 0.5 -0.3 0.7
Pain all over the body in last month 0.6 0.7 1.3 0.3 -1.1
Diabetes (self-reported) 0.1 0.2 0.4 -0.6 -0.2
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 0.8 0.9 -0.1
Medication: Ramipril 0.6 0.8 1.3 -1.1 0.5
Medication: Simvastatin 0.3 0.5 0.9 -1.0 -0.0
Fluid intelligence score 0.4 0.9 1.7 1.3 -0.4
Illnesses of siblings 0.7 1.0 1.6 -0.6 1.2
Neuroticism score 3.8 8.0 10.4 -3.2 2.4
Weight 0.4 1.7 3.0 -1.7 0.7
Impedance of arm (right) 0.0 0.1 0.3 0.5 -0.1
Arm fat percentage (right) 1.1 4.3 7.9 -2.8 0.9
Trunk fat-free mass 0.0 0.3 0.5 -0.3 0.7
Hip circumference 0.7 2.9 5.4 -2.3 0.6
Time employed in main current job 0.3 0.3 0.4 0.7 0.4
Alcohol intake versus 10 years previously 2.4 3.6 4.7 -2.2 1.6
Father’s age at death 3.6 4.9 6.9 2.6 -1.7
Worrier / anxious feelings 0.8 1.5 2.6 -1.6 0.7
Frequency of tiredness / lethargy in last 2 weeks 3.0 4.9 8.7 -3.0 1.0
Falls in the last year 0.5 0.7 1.4 -1.2 0.1
Hair/balding pattern: Pattern 3 0.1 0.2 0.2 0.3 0.5
Number of live births 0.2 0.3 0.5 0.5 -0.7
Forced expiratory volume in 1-second (FEV1) 0.3 1.0 1.9 -0.4 1.4
Pulse rate 0.2 0.3 0.6 0.2 0.8
Happiness 7.4 9.0 11.3 -3.4 2.6
Noisy workplace 2.2 2.8 3.1 -1.6 1.8
Qualifications: A levels/AS levels or equivalent 0.2 0.3 0.4 0.6 0.6
Serious illness, injury or assault of a close relative in last 2 years 2.0 2.3 3.4 1.8 -1.1
Mouth/teeth dental problems: Dentures 0.4 0.7 0.9 -0.9 -0.8
Asthma 0.1 0.1 0.2 -0.5 0.2
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 1.6 -1.3 0.1
Medication: Cholesterol lowering 0.6 0.9 1.6 0.5 -1.3
Depression (self-reported) 5.6 6.7 8.3 -2.3 2.9
Medication: Lansoprazole 0.2 0.2 0.4 -0.3 -0.6
Prospective memory result 0.3 0.3 0.6 0.0 -0.8
Lung cancer (father) 4.3 5.0 5.8 -2.4 2.1
Illnesses of mother 2.0 2.4 3.7 1.9 -1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.5 0.9 -0.2 1.0
Pulse wave Arterial Stiffness index 0.3 0.3 0.4 -0.4 -0.7
Impedance of arm (left) 0.1 0.4 0.6 0.8 -0.4
Arm fat mass (right) 0.8 3.4 6.2 -2.5 0.8
Trunk predicted mass 0.1 0.3 0.6 -0.3 0.8
Standing height 0.3 3.1 5.6 2.4 -0.8
Length of working week for main job 3.0 3.3 4.1 -1.6 2.0
Exposure to tobacco smoke at home 0.2 0.3 0.5 -0.2 -0.7
Breastfed as a baby 2.4 2.9 3.8 1.5 -1.9
Tense / ‘highly strung’ 0.7 1.1 1.5 -1.2 0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.5 2.4 -1.5 0.8
Hair/balding pattern: Pattern 4 0.0 0.1 0.2 0.1 0.4
Birth weight of first child 0.7 1.3 1.6 -1.0 1.3
Peak expiratory flow (PEF) 1.2 2.9 3.8 -1.9 1.4
Pulse wave reflection index 0.2 0.2 0.4 -0.6 0.1
Ever highly irritable/argumentative for 2 days 0.4 0.4 0.8 -0.4 -0.9
Loud music exposure frequency 0.0 0.0 0.0 -0.0 0.0
Qualifications: O levels/GCSEs or equivalent 2.4 3.9 5.4 -1.5 2.3
Mouth/teeth dental problems: Bleeding gums 0.1 0.2 0.2 -0.4 0.4
Blood clot in the leg (DVT) 2.0 2.6 3.6 -1.9 1.3
Medication: Paracetamol 0.3 0.5 1.1 0.1 -1.0
Headache pain in last month 1.9 3.3 6.1 -2.5 0.7
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 0.4 0.6 0.6
Glaucoma (self-reported) 1.2 1.4 1.8 -1.3 1.0
Gout (self-reported) 0.0 0.0 0.0 0.2 0.2
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.1 1.0 -0.4
Medication: Amlodipine 0.5 0.7 1.2 -0.5 1.1
Medication: Ventolin 100micrograms inhaler 1.3 1.6 1.9 -1.4 1.2
Birth weight 1.6 3.4 3.6 1.9 -1.8
Chronic bronchitis/emphysema (mother) 6.1 7.1 8.7 -2.3 2.9
High blood pressure (siblings) 0.1 0.1 0.2 0.3 -0.4
Forced vital capacity (FVC), Best measure 0.2 0.6 1.1 0.0 1.1
Body fat percentage 0.7 2.8 5.5 -2.4 0.4
Leg fat percentage (right) 0.7 2.6 5.2 -2.3 -0.0
Arm fat-free mass (right) 0.1 0.3 0.4 -0.6 0.5
Exposure to tobacco smoke outside home 0.3 0.5 0.9 -1.0 0.0
Comparative body size at age 10 0.3 0.9 1.7 -1.3 -0.3
Number of full brothers 0.1 0.1 0.1 -0.3 0.2
Worry too long after embarrassment 0.1 0.1 0.2 -0.2 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 1.9 -1.4 0.6
Wheeze or whistling in the chest in last year 0.1 0.2 0.4 -0.6 0.3
Number of children fathered 0.1 0.1 0.1 -0.3 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.7 2.4 1.5 -1.0
Age at first live birth 0.0 0.0 0.0 0.1 -0.1
Pulse wave peak to peak time 0.3 0.3 0.4 0.4 0.7
Health satisfaction 4.0 5.2 6.5 -2.6 2.0
Shortness of breath walking on level ground 0.1 0.1 0.3 0.5 -0.1
Qualifications: College or University degree 0.3 0.9 1.8 1.4 0.2
Eye problems/disorders: None of the above 1.4 1.7 2.2 1.1 -1.5
Mouth/teeth dental problems: Loose teeth 0.8 1.0 1.0 -1.0 1.0
Emphysema/chronic bronchitis 1.4 1.5 2.6 -1.6 0.7
Medication for pain relief, constipation, heartburn 0.2 0.4 0.7 0.9 0.3
Neck or shoulder pain in last month 1.0 1.4 1.8 -1.3 1.0
Medication: Blood pressure 0.2 0.3 0.5 -0.7 -0.3
Angina (self-reported) 0.3 0.4 0.7 -0.8 0.2
Migraine (self-reported) 0.3 0.3 0.4 0.6 -0.6
Medication: Ibuprofen 1.7 2.0 3.5 -1.9 0.7
Medication: Allopurinol 1.1 1.4 1.7 1.1 -1.3
Medication: Omeprazole 4.2 5.1 6.0 -2.4 2.0
Medication: Seretide 50 evohaler 1.0 1.1 1.4 -1.2 1.0
Mean time to correctly identify matches 1.7 3.2 4.5 1.4 -2.1
Heart disease (mother) 0.1 0.2 0.3 0.1 -0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.0 0.0 0.0 0.1 0.1
Whole body fat mass 0.7 3.0 5.8 -2.4 0.5
Leg fat mass (right) 0.8 3.2 6.1 -2.5 0.4
Arm predicted mass (right) 0.0 0.1 0.2 -0.4 0.3
Pulse rate, automated reading 0.2 0.6 0.8 0.9 0.7
Alcohol intake frequency. 1.0 2.4 4.2 -2.0 0.7
Comparative height size at age 10 0.4 2.1 4.0 2.0 -0.3
Number of full sisters 0.7 0.8 1.6 0.0 -1.3
Suffer from ‘nerves’ 5.1 8.0 8.2 -2.8 2.9
Overall health rating 5.9 12.6 19.4 -4.4 2.4
Chest pain or discomfort 0.0 0.0 0.0 -0.2 0.1
Had major operations 1.0 1.2 2.3 -0.2 1.5
Age at last live birth 0.8 1.2 1.2 1.1 -1.1
Family relationship satisfaction 0.2 0.2 0.3 0.3 0.5
Leg pain on walking 0.0 0.1 0.1 0.3 -0.1
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 1.9 1.4 -0.7
Commuting to job workplace: Car/motor vehicle 0.2 0.2 0.3 -0.4 0.5
Illness, injury, bereavement, stress in last 2 years 0.0 0.0 0.0 0.2 -0.1
Medication: Aspirin 0.0 0.0 0.1 0.0 -0.3
Supplements: Vitamin C 0.2 0.2 0.4 -0.6 0.3
Knee pain experienced in last month 0.5 0.8 1.3 -1.2 -0.4
Hypertension (Self-reported) 0.4 1.1 1.9 -1.4 0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 0.5 -0.4 -0.7
Illnesses of father: Heart disease 0.7 1.0 1.2 -1.1 0.9
Illnesses of siblings: Diabetes 2.7 3.3 5.1 1.2 -2.2
Smoking status: Previous 0.1 0.2 0.3 -0.6 0.3
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 0.7 0.9 -0.7
Whole body fat-free mass 0.2 0.9 1.1 -0.9 1.0
Leg fat-free mass (right) 0.5 2.6 2.7 -1.6 1.6
Arm fat percentage (left) 1.0 4.0 7.5 -2.7 0.7
Average weekly red wine intake 1.6 2.4 2.4 1.5 -1.5
Handedness (chirality/laterality): Left-handed 0.0 0.0 0.1 -0.3 0.1
Mood swings 3.7 6.6 10.5 -3.2 1.7
Loneliness, isolation 0.6 0.8 1.5 -0.4 1.2
Long-standing illness, disability or infirmity 0.2 0.3 0.3 0.5 -0.5
Ever had bowel cancer screening 0.4 0.5 0.7 0.5 -0.9
Diabetes diagnosed by doctor 0.0 0.0 0.0 -0.1 -0.1
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.4 -0.1 -0.6
Friendships satisfaction 0.1 0.1 0.1 -0.3 0.3
Qualifications: nursing, teaching 0.5 0.7 0.9 0.8 -1.0
Commuting to job workplace: Walk 0.6 0.6 1.2 1.1 -0.1
Eye problems/disorders: Cataract 0.1 0.2 0.2 -0.3 0.5
Mouth/teeth dental problems: Mouth ulcers 0.7 1.2 1.3 -1.0 1.1
Medication for cholesterol 0.4 0.6 0.9 0.6 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.1 -0.3 0.3
Back pain experienced in last month 0.9 1.3 2.3 -1.5 -0.6
Mineral and other dietary supplements 0.4 0.5 0.6 0.8 -0.6
Breast cancer (self-reported) 0.1 0.1 0.1 -0.3 0.2
Asthma (self-reported) 0.0 0.0 0.1 -0.3 -0.0
Osteoporosis (self-reported) 0.0 0.0 0.0 -0.2 0.1
Osteoarthritis (self-reported) 0.2 0.3 0.6 -0.8 0.0
Medication: Aspirin 0.0 0.0 0.0 -0.2 0.0
Medication: Gliclazide 0.7 0.8 1.0 -0.8 1.0
Illnesses of father: None of the above (group 1) 0.2 0.3 0.5 -0.3 0.7
Smoking status: Current 0.1 0.2 0.3 -0.6 0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.9 1.4 -0.6 1.2
Whole body water mass 0.1 0.7 0.8 -0.8 0.9
Leg predicted mass (right) 0.5 2.6 2.7 -1.6 1.6
Arm fat mass (left) 0.8 3.3 6.1 -2.5 0.8
Number of self-reported non-cancer illnesses 1.3 2.2 3.9 -2.0 0.7
Average weekly champagne plus white wine intake 0.3 0.5 0.8 0.4 0.9
Miserableness 6.8 11.7 13.8 -3.7 3.1
Guilty feelings 0.6 0.9 1.7 -0.3 1.3
Wears glasses or contact lenses 1.4 1.6 2.0 1.4 -1.1
Ever taken oral contraceptive pill 0.1 0.1 0.3 0.5 -0.2
Hearing aid user 0.1 0.1 0.1 0.2 0.3
Mother’s age at death 0.1 0.2 0.4 0.6 0.1
Financial situation satisfaction 2.1 2.5 3.9 -2.0 1.1
Tinnitus: Yes, now most or all of the time 0.9 1.0 1.2 -0.9 1.1
Commuting to job workplace: Public transport 0.0 0.0 0.0 0.2 0.2
Eye problems/disorders: Glaucoma 0.3 0.4 0.5 -0.7 0.5
Medication: Blood pressure 0.7 1.3 1.7 -1.3 1.0
Pain type(s) experienced in last month: Hip pain 1.7 2.2 4.2 -2.1 0.4
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.2 -0.1 0.5
High cholesterol (Self-reported) 0.1 0.2 0.2 -0.4 -0.5
Medication: Bendroflumethiazide 0.1 0.2 0.3 0.1 -0.6
Medication: Paracetamol 0.2 0.3 0.7 -0.2 -0.8
Medication: Lisinopril 0.5 0.6 0.9 0.5 -0.9
Medication: Atorvastatin 0.3 0.3 0.4 0.5 -0.6
Illnesses of father: High blood pressure 0.4 0.5 1.0 -1.0 0.2
Alcohol drinker status: Never 2.1 2.5 4.0 -2.0 1.0
Ever smoked 0.5 0.8 1.6 0.2 -1.2
Basal metabolic rate 0.2 1.2 1.2 -1.1 1.0
Leg fat percentage (left) 0.8 3.0 5.9 -2.4 0.4
Arm fat-free mass (left) 0.1 0.7 0.9 -0.9 0.7
Number of operations (self-reported) 2.2 3.2 4.2 -2.0 1.5
Average weekly beer plus cider intake 0.0 0.1 0.1 -0.4 -0.1
Irritability 1.7 2.8 3.0 -1.6 1.7
Risk taking 0.1 0.2 0.4 0.6 -0.2
Ever had prostate specific antigen (PSA) test 0.5 0.5 0.9 0.3 -1.0
Fractured/broken bones in last 5 years 1.4 1.8 2.2 -1.5 1.2
Age started oral contraceptive pill 2.2 2.7 3.1 1.6 -1.8
Diastolic blood pressure, automated reading 1.7 5.3 5.9 -2.4 2.2
Ever depressed for a whole week 0.1 0.1 0.2 -0.1 0.4
Unable to work because of sickness or disability 0.8 1.0 1.9 -1.4 0.2
Commuting to job workplace: Cycle 2.5 3.0 3.8 2.0 -1.5
Myopia 2.8 4.1 5.4 2.3 -1.7
Vascular/heart problems diagnosed by doctor 0.7 1.8 2.8 1.7 -0.9
Cholesterol lowering medication 0.0 0.1 0.1 0.1 -0.3
Medication: Omeprazole (e.g. Zanprol) 2.8 3.4 3.4 -1.8 1.9
Pain experienced in last month 1.2 1.9 3.2 1.8 0.8
Supplements: Calcium 1.4 1.5 2.3 -1.5 0.8
Basal cell carcinoma (self-reported) 0.3 0.4 0.7 -0.2 0.8
Heart attack/myocardial infarction (self-reported) 0.0 0.0 0.0 -0.2 0.1
Deep venous thrombosis (DVT) (self-reported) 2.3 3.0 3.8 -1.9 1.5
Heart disease (siblings) 0.3 0.4 0.4 -0.7 0.5
Alcohol drinker status: Previous 0.1 0.2 0.2 0.4 -0.4
Pack years of smoking 0.2 0.3 0.7 -0.8 -0.1
Impedance of whole body 0.3 1.4 1.9 1.4 -0.9
Leg fat mass (left) 0.9 3.5 6.6 -2.6 0.6
Arm predicted mass (left) 0.2 0.8 1.2 -1.1 0.7