TWAS hub - SLFN14

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0131	0.0057	0.0029	0.005	0.004	0.002	0.004	0.001	0.0061	0.014	0.056	0.012	0.20
2	TCGA	Colon Adenocarcinoma	0.0470	0.0290	0.0091	0.010	0.021	0.006	NA	0.001	0.0790	0.022	0.140	NA	0.26

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Alcohol usually taken with meals	8.1	13.1	16.2	4.0	-3.2
Frequency of depressed mood in last 2 weeks	7.6	10.6	13.1	-3.6	2.9
Happiness	7.4	9.0	11.3	-3.4	2.6
Blood Platelet Count	7.1	82.3	102.0	7.9	-10.1
Miserableness	6.8	11.7	13.8	-3.7	3.1
Chronic bronchitis/emphysema (mother)	6.1	7.1	8.7	-2.3	2.9
Overall health rating	5.9	12.6	19.4	-4.4	2.4
Depression (self-reported)	5.6	6.7	8.3	-2.3	2.9
Depression (Nagel 2018)	5.1	7.6	9.9	-3.1	2.3
Suffer from ‘nerves’	5.1	8.0	8.2	-2.8	2.9
Lung cancer (father)	4.3	5.0	5.8	-2.4	2.1
Fed-up feelings	4.2	7.6	10.7	-3.3	2.1
Medication: Omeprazole	4.2	5.1	6.0	-2.4	2.0
Health satisfaction	4.0	5.2	6.5	-2.6	2.0
Serious illness, injury or assault to yourself	3.9	4.8	6.2	-1.8	2.5
Depressed Affect (Nagel 2018)	3.8	7.9	10.0	-3.2	2.4
Neuroticism score	3.8	8.0	10.4	-3.2	2.4
Neuroticism (2016)	3.7	5.4	8.1	-2.9	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	3.7	4.9	5.6	-2.4	2.1
Mood swings	3.7	6.6	10.5	-3.2	1.7
Father’s age at death	3.6	4.9	6.9	2.6	-1.7
Taking other prescription medications	3.2	4.9	6.4	-2.5	1.9
Frequency of tenseness / restlessness in last 2 weeks	3.2	5.1	7.0	-2.6	1.8
Frequency of tiredness / lethargy in last 2 weeks	3.0	4.9	8.7	-3.0	1.0
Length of working week for main job	3.0	3.3	4.1	-1.6	2.0
Ever had hysterectomy (womb removed)	2.9	3.2	5.8	0.8	-2.4
Myopia	2.8	4.1	5.4	2.3	-1.7
Medication: Omeprazole (e.g. Zanprol)	2.8	3.4	3.4	-1.8	1.9
Age at First Birth	2.7	4.0	5.6	2.4	-1.5
Illnesses of siblings: Diabetes	2.7	3.3	5.1	1.2	-2.2
Verbal and Numeric Reasoning (VNR)	2.5	5.9	10.5	3.2	-1.2
Neuroticism	2.5	6.1	8.6	-2.9	1.9
Commuting to job workplace: Cycle	2.5	3.0	3.8	2.0	-1.5
Medication: Co-codamol	2.4	2.8	3.8	-2.0	1.3
Alcohol intake versus 10 years previously	2.4	3.6	4.7	-2.2	1.6
Breastfed as a baby	2.4	2.9	3.8	1.5	-1.9
Qualifications: O levels/GCSEs or equivalent	2.4	3.9	5.4	-1.5	2.3
Smoking Status	2.3	5.5	6.4	-2.1	2.5
Deep venous thrombosis (DVT) (self-reported)	2.3	3.0	3.8	-1.9	1.5
Neuroticism (Nagel 2018)	2.2	5.1	6.6	-2.6	1.9
Noisy workplace	2.2	2.8	3.1	-1.6	1.8
Number of operations (self-reported)	2.2	3.2	4.2	-2.0	1.5
Age started oral contraceptive pill	2.2	2.7	3.1	1.6	-1.8
Had menopause	2.1	2.6	4.5	0.8	-2.1
Financial situation satisfaction	2.1	2.5	3.9	-2.0	1.1
Alcohol drinker status: Never	2.1	2.5	4.0	-2.0	1.0
Townsend deprivation index at recruitment	2.0	2.8	3.4	-1.5	1.9
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	3.4	1.8	-1.1
Illnesses of mother	2.0	2.4	3.7	1.9	-1.1
Blood clot in the leg (DVT)	2.0	2.6	3.6	-1.9	1.3
Ever used hormone-replacement therapy (HRT)	1.9	2.5	3.2	1.3	-1.8
Qualifications: None of the above	1.9	4.2	7.9	-2.8	0.7
Headache pain in last month	1.9	3.3	6.1	-2.5	0.7
Number of incorrect matches in round	1.8	3.0	3.3	1.6	-1.8
Medication: Ibuprofen	1.7	2.0	3.5	-1.9	0.7
Mean time to correctly identify matches	1.7	3.2	4.5	1.4	-2.1
Pain type(s) experienced in last month: Hip pain	1.7	2.2	4.2	-2.1	0.4
Irritability	1.7	2.8	3.0	-1.6	1.7
Diastolic blood pressure, automated reading	1.7	5.3	5.9	-2.4	2.2
Hypothyroidism (self reported)	1.6	3.7	6.2	2.5	-1.1
Supplements: Zinc	1.6	1.7	2.5	-1.6	1.0
Hair/balding pattern: Pattern 2	1.6	2.0	3.0	1.0	-1.7
Birth weight	1.6	3.4	3.6	1.9	-1.8
Average weekly red wine intake	1.6	2.4	2.4	1.5	-1.5
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	2.0	-1.4	1.4
Multivitamins +/- minerals	1.5	2.0	3.0	-1.7	1.0
Schizophrenia (2018)	1.4	2.9	4.9	2.2	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	2.4	1.5	-1.0
Eye problems/disorders: None of the above	1.4	1.7	2.2	1.1	-1.5
Emphysema/chronic bronchitis	1.4	1.5	2.6	-1.6	0.7
Wears glasses or contact lenses	1.4	1.6	2.0	1.4	-1.1
Fractured/broken bones in last 5 years	1.4	1.8	2.2	-1.5	1.2
Supplements: Calcium	1.4	1.5	2.3	-1.5	0.8
Worry (Nagel 2018)	1.3	2.7	3.2	-1.8	1.5
LDL Cholesterol	1.3	2.0	2.4	-1.5	1.3
Medication: Ventolin 100micrograms inhaler	1.3	1.6	1.9	-1.4	1.2
Number of self-reported non-cancer illnesses	1.3	2.2	3.9	-2.0	0.7
Intelligence (Savage-Jansen 2018)	1.2	3.8	7.3	2.7	-0.5
Reaction Time	1.2	2.2	3.3	1.1	-1.8
Prostate Cancer	1.2	1.7	2.9	-0.8	1.7
Schizophrenia (2014)	1.2	2.7	3.2	1.8	-1.4
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	2.7	0.1	-1.6
Body mass index (BMI)	1.2	5.0	8.6	-2.9	1.1
Peak expiratory flow (PEF)	1.2	2.9	3.8	-1.9	1.4
Glaucoma (self-reported)	1.2	1.4	1.8	-1.3	1.0
Pain experienced in last month	1.2	1.9	3.2	1.8	0.8
Schizophrenia vs Biploar Disorder	1.1	1.4	1.8	1.3	-1.0
Crohns Disease (2012)	1.1	1.7	2.5	-0.9	1.6
Allergy or Eczema	1.1	2.8	3.0	1.6	-1.7
Arm fat percentage (right)	1.1	4.3	7.9	-2.8	0.9
Medication: Allopurinol	1.1	1.4	1.7	1.1	-1.3
Number of treatments/medications taken	1.0	1.7	2.3	-1.5	1.1
Hearing difficulty/problems with background noise	1.0	1.5	2.3	-1.5	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	2.4	-1.5	0.8
Neck or shoulder pain in last month	1.0	1.4	1.8	-1.3	1.0
Medication: Seretide 50 evohaler	1.0	1.1	1.4	-1.2	1.0
Alcohol intake frequency.	1.0	2.4	4.2	-2.0	0.7
Had major operations	1.0	1.2	2.3	-0.2	1.5
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	1.9	1.4	-0.7
Arm fat percentage (left)	1.0	4.0	7.5	-2.7	0.7
Major Depression (MDD)	0.9	1.1	1.6	-1.3	-0.8
Coronary Artery Disease (CAD)	0.9	1.1	1.4	0.9	-1.2
BMI	0.9	5.1	7.3	-2.7	1.7
Sensitivity / hurt feelings	0.9	1.6	3.1	-1.8	0.4
Diabetes (mother)	0.9	1.1	1.7	-1.3	0.8
Severe depression (siblings)	0.9	1.0	1.9	-0.1	1.4
Impedance of leg (right)	0.9	4.5	5.3	2.3	-1.9
Chronic bronchitis/emphysema (father)	0.9	1.1	1.2	-1.0	1.1
Back pain experienced in last month	0.9	1.3	2.3	-1.5	-0.6
Tinnitus: Yes, now most or all of the time	0.9	1.0	1.2	-0.9	1.1
Leg fat mass (left)	0.9	3.5	6.6	-2.6	0.6
Triglycerides	0.8	1.4	1.4	-1.2	1.1
Impedance of leg (left)	0.8	4.1	5.3	2.3	-1.7
Nervous feelings	0.8	1.4	2.5	-0.6	1.6
Worrier / anxious feelings	0.8	1.5	2.6	-1.6	0.7
Arm fat mass (right)	0.8	3.4	6.2	-2.5	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	1.9	-1.4	0.6
Mouth/teeth dental problems: Loose teeth	0.8	1.0	1.0	-1.0	1.0
Leg fat mass (right)	0.8	3.2	6.1	-2.5	0.4
Age at last live birth	0.8	1.2	1.2	1.1	-1.1
Arm fat mass (left)	0.8	3.3	6.1	-2.5	0.8
Leg fat percentage (left)	0.8	3.0	5.9	-2.4	0.4
Unable to work because of sickness or disability	0.8	1.0	1.9	-1.4	0.2
Chronotype (morning person)	0.7	1.5	2.5	1.6	-0.8
Systolic blood pressure, automated reading	0.7	2.0	3.9	-2.0	0.3
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	0.9	0.8	-0.9
Financial difficulties in last 2 years	0.7	1.0	1.7	-1.3	0.5
Mouth/teeth dental problems	0.7	1.1	1.8	1.4	-0.5
Illnesses of siblings	0.7	1.0	1.6	-0.6	1.2
Hip circumference	0.7	2.9	5.4	-2.3	0.6
Tense / ‘highly strung’	0.7	1.1	1.5	-1.2	0.9
Birth weight of first child	0.7	1.3	1.6	-1.0	1.3
Body fat percentage	0.7	2.8	5.5	-2.4	0.4
Leg fat percentage (right)	0.7	2.6	5.2	-2.3	-0.0
Whole body fat mass	0.7	3.0	5.8	-2.4	0.5
Number of full sisters	0.7	0.8	1.6	0.0	-1.3
Illnesses of father: Heart disease	0.7	1.0	1.2	-1.1	0.9
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	1.3	-1.0	1.1
Medication: Gliclazide	0.7	0.8	1.0	-0.8	1.0
Medication: Blood pressure	0.7	1.3	1.7	-1.3	1.0
Vascular/heart problems diagnosed by doctor	0.7	1.8	2.8	1.7	-0.9
Ulcerative Colitis (UC)	0.6	1.2	2.1	1.5	-0.5
Primary Biliary Cirrhosis	0.6	0.8	1.3	-0.6	-1.1
Blood Red Count	0.6	6.2	6.6	-2.4	2.6
Trunk fat percentage	0.6	2.3	4.5	-2.1	0.4
Medication: Atenolol	0.6	0.8	1.2	-1.1	0.6
Pain all over the body in last month	0.6	0.7	1.3	0.3	-1.1
Medication: Ramipril	0.6	0.8	1.3	-1.1	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.6	-1.3	0.1
Medication: Cholesterol lowering	0.6	0.9	1.6	0.5	-1.3
Loneliness, isolation	0.6	0.8	1.5	-0.4	1.2
Commuting to job workplace: Walk	0.6	0.6	1.2	1.1	-0.1
Guilty feelings	0.6	0.9	1.7	-0.3	1.3
Bipolar Disorder or Schizophrenia	0.5	1.1	2.2	1.5	-0.3
Blood Eosinophil Count	0.5	3.5	4.0	1.8	-2.0
Waist Hip Ratio (WHR)	0.5	2.4	4.8	2.2	-0.3
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.0	1.0	0.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	0.8	0.6	-0.9
Supplements: Glucosamine	0.5	0.7	1.2	-1.1	0.5
Sitting height	0.5	3.2	6.2	2.5	-0.6
Trunk fat mass	0.5	2.2	4.3	-2.1	0.4
Falls in the last year	0.5	0.7	1.4	-1.2	0.1
Medication: Amlodipine	0.5	0.7	1.2	-0.5	1.1
Knee pain experienced in last month	0.5	0.8	1.3	-1.2	-0.4
Leg fat-free mass (right)	0.5	2.6	2.7	-1.6	1.6
Qualifications: nursing, teaching	0.5	0.7	0.9	0.8	-1.0
Leg predicted mass (right)	0.5	2.6	2.7	-1.6	1.6
Medication: Lisinopril	0.5	0.6	0.9	0.5	-0.9
Ever smoked	0.5	0.8	1.6	0.2	-1.2
Ever had prostate specific antigen (PSA) test	0.5	0.5	0.9	0.3	-1.0
Body Mass Index (BMI) (2010)	0.4	0.5	0.7	0.8	-0.6
Mean Putamen Volume	0.4	0.4	0.8	-0.3	-0.9
HbA1C	0.4	0.4	0.5	0.6	-0.7
Cardiovascular Disease	0.4	1.2	1.9	-1.4	0.7
Angina	0.4	0.6	1.1	-1.0	0.3
Leg fat-free mass (left)	0.4	2.1	2.4	-1.6	1.3
Qualifications: CSEs or equivalent	0.4	0.5	0.9	-1.0	-0.4
High blood pressure	0.4	1.2	2.1	-1.4	0.6
Hayfever, allergic rhinitis or eczema	0.4	0.9	0.9	0.9	-1.0
Leg predicted mass (left)	0.4	2.2	2.6	-1.6	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	1.6	-0.5	-1.3
Fluid intelligence score	0.4	0.9	1.7	1.3	-0.4
Weight	0.4	1.7	3.0	-1.7	0.7
Mouth/teeth dental problems: Dentures	0.4	0.7	0.9	-0.9	-0.8
Ever highly irritable/argumentative for 2 days	0.4	0.4	0.8	-0.4	-0.9
Comparative height size at age 10	0.4	2.1	4.0	2.0	-0.3
Hypertension (Self-reported)	0.4	1.1	1.9	-1.4	0.5
Ever had bowel cancer screening	0.4	0.5	0.7	0.5	-0.9
Medication for cholesterol	0.4	0.6	0.9	0.6	-1.0
Mineral and other dietary supplements	0.4	0.5	0.6	0.8	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.4	-0.6	1.2
Illnesses of father: High blood pressure	0.4	0.5	1.0	-1.0	0.2
Irritable Bowel Disease (IBD)	0.3	0.7	1.3	1.1	-0.2
Bipolar Disorder (2011)	0.3	0.3	0.6	0.8	0.0
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.8	0.1	0.9
Ulcerative Colitis	0.3	0.4	0.6	0.8	-0.6
Systolic Blood Pressure	0.3	1.7	2.8	-1.7	0.7
Vitamin and mineral supplements	0.3	0.4	0.7	0.9	-0.2
Diabetes (father)	0.3	0.4	0.5	-0.7	0.5
Current tobacco smoking	0.3	0.4	0.8	-0.9	0.3
Maternal smoking around birth	0.3	0.5	0.9	-0.3	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.3	-0.3	-1.1
High blood pressure (mother)	0.3	0.4	0.9	-0.9	-0.0
Waist circumference	0.3	0.9	1.8	-1.3	0.1
Had other major operations	0.3	0.4	0.7	0.9	0.1
Forced vital capacity (FVC)	0.3	1.3	2.6	-0.1	1.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.8	0.9	-0.1
Medication: Simvastatin	0.3	0.5	0.9	-1.0	-0.0
Time employed in main current job	0.3	0.3	0.4	0.7	0.4
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	1.9	-0.4	1.4
Prospective memory result	0.3	0.3	0.6	0.0	-0.8
Pulse wave Arterial Stiffness index	0.3	0.3	0.4	-0.4	-0.7
Standing height	0.3	3.1	5.6	2.4	-0.8
Medication: Paracetamol	0.3	0.5	1.1	0.1	-1.0
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.1	1.0	-0.4
Exposure to tobacco smoke outside home	0.3	0.5	0.9	-1.0	0.0
Comparative body size at age 10	0.3	0.9	1.7	-1.3	-0.3
Pulse wave peak to peak time	0.3	0.3	0.4	0.4	0.7
Qualifications: College or University degree	0.3	0.9	1.8	1.4	0.2
Angina (self-reported)	0.3	0.4	0.7	-0.8	0.2
Migraine (self-reported)	0.3	0.3	0.4	0.6	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.5	-0.4	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	0.7	0.9	-0.7
Average weekly champagne plus white wine intake	0.3	0.5	0.8	0.4	0.9
Eye problems/disorders: Glaucoma	0.3	0.4	0.5	-0.7	0.5
Medication: Atorvastatin	0.3	0.3	0.4	0.5	-0.6
Basal cell carcinoma (self-reported)	0.3	0.4	0.7	-0.2	0.8
Heart disease (siblings)	0.3	0.4	0.4	-0.7	0.5
Impedance of whole body	0.3	1.4	1.9	1.4	-0.9
Bipolar Disorder (2018)	0.2	0.3	0.5	-0.4	0.7
Alzheimer’s Disease (in father)	0.2	0.2	0.4	0.2	-0.6
Fasting Glucose	0.2	0.3	0.4	-0.6	-0.4
Heel T-Score	0.2	1.3	2.5	-1.6	0.3
Type 2 Diabetes (T2D) (2018)	0.2	0.3	0.6	-0.8	-0.2
Average weekly spirits intake	0.2	0.2	0.4	0.6	0.1
Relative age of first facial hair	0.2	0.5	1.0	-0.0	1.0
Pack years adult smoking proportion	0.2	0.3	0.7	-0.8	-0.0
Hand grip strength (right)	0.2	0.5	0.6	-0.6	0.8
Relative age voice broke	0.2	0.3	0.4	-0.5	0.6
Age when periods started (menarche)	0.2	0.6	0.7	-0.9	0.7
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.4	0.2	-0.6
Number of live births	0.2	0.3	0.5	0.5	-0.7
Pulse rate	0.2	0.3	0.6	0.2	0.8
Qualifications: A levels/AS levels or equivalent	0.2	0.3	0.4	0.6	0.6
Medication: Lansoprazole	0.2	0.2	0.4	-0.3	-0.6
Exposure to tobacco smoke at home	0.2	0.3	0.5	-0.2	-0.7
Pulse wave reflection index	0.2	0.2	0.4	-0.6	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.4	0.6	0.6
Forced vital capacity (FVC), Best measure	0.2	0.6	1.1	0.0	1.1
Medication for pain relief, constipation, heartburn	0.2	0.4	0.7	0.9	0.3
Medication: Blood pressure	0.2	0.3	0.5	-0.7	-0.3
Pulse rate, automated reading	0.2	0.6	0.8	0.9	0.7
Family relationship satisfaction	0.2	0.2	0.3	0.3	0.5
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.3	-0.4	0.5
Supplements: Vitamin C	0.2	0.2	0.4	-0.6	0.3
Whole body fat-free mass	0.2	0.9	1.1	-0.9	1.0
Long-standing illness, disability or infirmity	0.2	0.3	0.3	0.5	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.4	-0.1	-0.6
Osteoarthritis (self-reported)	0.2	0.3	0.6	-0.8	0.0
Illnesses of father: None of the above (group 1)	0.2	0.3	0.5	-0.3	0.7
Medication: Paracetamol	0.2	0.3	0.7	-0.2	-0.8
Basal metabolic rate	0.2	1.2	1.2	-1.1	1.0
Pack years of smoking	0.2	0.3	0.7	-0.8	-0.1
Arm predicted mass (left)	0.2	0.8	1.2	-1.1	0.7
Alzheimer’s Disease (in mother)	0.1	0.1	0.1	-0.3	-0.3
Alzheimer’s Disease (including proxy)	0.1	0.1	0.2	-0.5	0.0
Breast Cancer	0.1	0.2	0.4	-0.6	0.1
Ovarian Cancer	0.1	0.2	0.3	0.2	-0.5
HDL Cholesterol	0.1	0.2	0.5	0.1	-0.7
Lupus	0.1	0.2	0.2	0.5	-0.5
Rheumatoid Arthritis	0.1	0.1	0.2	-0.0	0.4
Height	0.1	2.8	4.4	2.1	-1.1
Respiratory disease	0.1	0.2	0.2	-0.5	0.5
Lung FVC	0.1	0.6	1.1	0.2	1.0
Tanning	0.1	1.6	2.8	1.7	-0.6
Hand grip strength (left)	0.1	0.2	0.4	0.6	-0.1
Hearing difficulty/problems: Yes	0.1	0.1	0.2	0.1	-0.5
Medication: Metformin	0.1	0.2	0.2	0.5	-0.4
Average weekly fortified wine intake	0.1	0.1	0.3	0.5	-0.1
Stomach or abdominal pain in last month	0.1	0.1	0.1	-0.2	0.3
Medication: Levothyroxine sodium	0.1	0.2	0.2	0.4	-0.4
Allergy	0.1	0.3	0.5	-0.3	0.7
Diabetes (self-reported)	0.1	0.2	0.4	-0.6	-0.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.2	0.3	0.5
Asthma	0.1	0.1	0.2	-0.5	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.5	0.9	-0.2	1.0
Impedance of arm (left)	0.1	0.4	0.6	0.8	-0.4
Trunk predicted mass	0.1	0.3	0.6	-0.3	0.8
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.2	-0.4	0.4
High blood pressure (siblings)	0.1	0.1	0.2	0.3	-0.4
Arm fat-free mass (right)	0.1	0.3	0.4	-0.6	0.5
Number of full brothers	0.1	0.1	0.1	-0.3	0.2
Worry too long after embarrassment	0.1	0.1	0.2	-0.2	0.5
Wheeze or whistling in the chest in last year	0.1	0.2	0.4	-0.6	0.3
Number of children fathered	0.1	0.1	0.1	-0.3	-0.1
Shortness of breath walking on level ground	0.1	0.1	0.3	0.5	-0.1
Heart disease (mother)	0.1	0.2	0.3	0.1	-0.6
Smoking status: Previous	0.1	0.2	0.3	-0.6	0.3
Friendships satisfaction	0.1	0.1	0.1	-0.3	0.3
Eye problems/disorders: Cataract	0.1	0.2	0.2	-0.3	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.1	-0.3	0.3
Breast cancer (self-reported)	0.1	0.1	0.1	-0.3	0.2
Smoking status: Current	0.1	0.2	0.3	-0.6	0.3
Whole body water mass	0.1	0.7	0.8	-0.8	0.9
Ever taken oral contraceptive pill	0.1	0.1	0.3	0.5	-0.2
Hearing aid user	0.1	0.1	0.1	0.2	0.3
Mother’s age at death	0.1	0.2	0.4	0.6	0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.2	-0.1	0.5
High cholesterol (Self-reported)	0.1	0.2	0.2	-0.4	-0.5
Medication: Bendroflumethiazide	0.1	0.2	0.3	0.1	-0.6
Arm fat-free mass (left)	0.1	0.7	0.9	-0.9	0.7
Risk taking	0.1	0.2	0.4	0.6	-0.2
Ever depressed for a whole week	0.1	0.1	0.2	-0.1	0.4
Alcohol drinker status: Previous	0.1	0.2	0.2	0.4	-0.4
Crohns Disease (2017)	0.0	0.1	0.1	0.4	0.0
Blood White Count	0.0	0.2	0.4	-0.3	-0.6
Lung FEV1/FVC ratio	0.0	0.0	0.1	-0.1	-0.3
Hair Pigment	0.0	0.5	0.8	-0.4	-0.9
Medication for hormone replacement therapy	0.0	0.0	0.0	-0.0	0.2
Past tobacco smoking	0.0	0.0	0.1	0.1	0.3
Heart attack	0.0	0.0	0.1	-0.2	0.2
Impedance of arm (right)	0.0	0.1	0.3	0.5	-0.1
Trunk fat-free mass	0.0	0.3	0.5	-0.3	0.7
Hair/balding pattern: Pattern 4	0.0	0.1	0.2	0.1	0.4
Loud music exposure frequency	0.0	0.0	0.0	-0.0	0.0
Gout (self-reported)	0.0	0.0	0.0	0.2	0.2
Age at first live birth	0.0	0.0	0.0	0.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.0	0.1	0.1
Arm predicted mass (right)	0.0	0.1	0.2	-0.4	0.3
Chest pain or discomfort	0.0	0.0	0.0	-0.2	0.1
Leg pain on walking	0.0	0.1	0.1	0.3	-0.1
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.0	0.2	-0.1
Medication: Aspirin	0.0	0.0	0.1	0.0	-0.3
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.1	-0.3	0.1
Diabetes diagnosed by doctor	0.0	0.0	0.0	-0.1	-0.1
Asthma (self-reported)	0.0	0.0	0.1	-0.3	-0.0
Osteoporosis (self-reported)	0.0	0.0	0.0	-0.2	0.1
Medication: Aspirin	0.0	0.0	0.0	-0.2	0.0
Commuting to job workplace: Public transport	0.0	0.0	0.0	0.2	0.2
Average weekly beer plus cider intake	0.0	0.1	0.1	-0.4	-0.1
Cholesterol lowering medication	0.0	0.1	0.1	0.1	-0.3
Heart attack/myocardial infarction (self-reported)	0.0	0.0	0.0	-0.2	0.1

Hub : Genes

SLFN14

Models

Trait associations