TWAS hub - SLX1A-SULT1A3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.068	0.039	0.0060	0.003	NA	0.002	NA	0.000	2.2e-01	NA	0.2500	NA	0.32000
2	GTEx	Testis	0.074	0.038	0.0055	0.100	NA	0.061	NA	0.082	3.4e-05	NA	0.0011	NA	0.00016

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Waist circumference	24.0	87.7	148.8	12.2	5.2
Weight	22.6	110.9	176.9	13.3	6.7
Leg fat-free mass (right)	22.5	120.0	176.9	13.3	7.9
Leg predicted mass (right)	22.1	118.1	174.2	13.2	7.9
Leg predicted mass (left)	22.0	116.3	171.6	13.1	7.8
Leg fat-free mass (left)	21.9	116.2	171.6	13.1	7.8
Basal metabolic rate	21.7	119.9	182.2	13.5	7.6
Arm fat mass (left)	21.4	88.0	136.9	11.7	6.2
Arm fat mass (right)	20.8	85.6	134.6	11.6	6.0
Impedance of leg (right)	20.2	98.0	125.4	-11.2	-8.4
Whole body water mass	20.0	114.2	171.6	13.1	7.5
Body mass index (BMI)	19.9	84.9	123.6	11.1	6.8
Arm fat-free mass (left)	19.8	100.4	156.2	12.5	6.7
Whole body fat-free mass	19.6	112.0	169.0	13.0	7.4
Arm predicted mass (left)	19.5	99.1	156.2	12.5	6.5
Impedance of leg (left)	18.7	90.6	112.4	-10.6	-8.3
Hip circumference	18.5	79.6	123.2	11.1	6.0
Arm fat-free mass (right)	18.5	94.6	144.0	12.0	6.7
Arm predicted mass (right)	18.3	93.5	141.6	11.9	6.7
Number of incorrect matches in round	18.2	30.2	38.6	-6.2	-4.7
Blood Red Count	16.9	162.9	176.9	-12.2	-13.3
Impedance of whole body	16.8	85.7	106.1	-10.3	-8.1
BMI	16.7	97.1	146.4	12.1	6.9
Trunk predicted mass	16.6	95.0	146.4	12.1	6.6
Trunk fat-free mass	16.5	94.9	146.4	12.1	6.6
Whole body fat mass	15.9	66.3	108.2	10.4	5.0
Leg fat mass (left)	15.7	61.4	99.4	10.0	4.8
Leg fat mass (right)	14.8	57.3	92.0	9.6	4.8
Trunk fat mass	13.3	57.3	97.4	9.9	4.2
Arm fat percentage (left)	13.2	52.5	83.9	9.2	4.6
Arm fat percentage (right)	13.0	51.4	83.0	9.1	4.4
Impedance of arm (left)	11.2	51.8	65.0	-8.1	-6.2
Impedance of arm (right)	11.1	51.5	62.7	-7.9	-6.3
Medication: Bendroflumethiazide	10.9	16.5	21.8	4.7	3.3
Bipolar Disorder or Schizophrenia	9.7	23.6	37.9	-6.2	-3.1
Neck or shoulder pain in last month	9.1	12.9	13.4	3.7	3.5
Body fat percentage	7.9	31.1	53.9	7.3	2.9
Nervous feelings	7.8	14.5	28.9	-5.4	0.2
Comparative body size at age 10	7.8	21.5	33.8	5.8	3.0
Hand grip strength (left)	7.5	19.8	24.6	5.0	3.9
Schizophrenia (2014)	7.3	16.1	25.6	-5.1	-2.6
Alcohol intake versus 10 years previously	7.2	10.7	17.7	4.2	1.9
Schizophrenia (2018)	7.0	14.5	23.9	-4.9	-2.3
Eye problems/disorders: Cataract	6.9	8.0	13.1	-1.7	-3.6
Trunk fat percentage	6.8	27.2	48.6	7.0	2.4
Age when periods started (menarche)	6.8	16.3	27.9	-5.3	-2.2
Mouth/teeth dental problems: Dentures	6.5	10.9	15.5	3.9	2.5
Alcohol intake frequency.	6.4	15.0	24.1	4.9	2.4
Leg fat percentage (left)	6.4	23.1	39.7	6.3	2.6
Fed-up feelings	6.3	11.4	13.0	3.1	3.6
Number of children fathered	6.1	6.9	10.9	1.7	3.3
Blood Eosinophil Count	6.0	46.4	53.6	-7.3	-6.3
Primary Biliary Cirrhosis	5.9	8.3	14.6	1.4	3.8
Bipolar Disorder (2018)	5.7	9.1	13.9	-3.7	-2.1
Wheeze or whistling in the chest in last year	5.7	10.2	12.9	2.7	3.6
Qualifications: NVQ or HND or HNC or equivalent	5.4	6.5	9.3	3.0	1.9
Basal cell carcinoma (self-reported)	5.3	6.3	9.6	-1.7	-3.1
High blood pressure	5.1	14.3	21.8	4.7	2.6
Medication: Ibuprofen (e.g. Nurofen)	5.1	6.5	10.6	3.3	1.6
Medication: Blood pressure	5.1	9.8	13.6	3.7	2.4
Depressed Affect (Nagel 2018)	4.9	10.4	18.3	1.6	4.3
Leg fat percentage (right)	4.9	17.8	30.8	5.6	2.2
Hand grip strength (right)	4.8	13.0	16.4	4.1	3.1
Body Mass Index (BMI) (2010)	4.6	6.4	10.4	3.2	1.5
Hypertension (Self-reported)	4.6	12.8	19.4	4.4	2.5
Ever had hysterectomy (womb removed)	4.5	5.1	6.1	-2.0	-2.5
Medication: Aspirin	4.5	5.9	11.1	-0.9	-3.3
Tense / ‘highly strung’	4.4	7.3	13.5	-3.7	-1.1
Pulse wave reflection index	4.3	5.3	8.9	1.2	3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	4.2	5.4	7.7	-2.8	-1.8
Comparative height size at age 10	4.2	23.4	42.1	6.5	2.2
Eye problems/disorders: None of the above	4.1	4.7	9.4	0.2	3.1
Medication: Aspirin	4.1	5.3	9.8	-0.9	-3.1
Miserableness	4.1	7.2	11.6	1.7	3.4
Worry (Nagel 2018)	3.9	8.2	16.2	-4.0	0.5
High blood pressure (mother)	3.9	5.4	5.5	2.3	2.3
Vascular/heart problems diagnosed by doctor	3.9	10.7	16.7	-4.1	-2.2
Asthma (self-reported)	3.8	7.5	12.8	1.5	3.6
Mouth/teeth dental problems	3.4	5.3	5.7	-2.2	-2.4
Supplements: Vitamin C	3.4	4.0	4.8	-1.8	-2.2
Maternal smoking around birth	3.3	4.8	8.1	1.2	2.8
Ever unenthusiastic/disinterested for a whole week	3.3	4.1	7.1	-2.7	-1.0
Heel T-Score	3.2	25.8	41.5	-6.4	-3.2
Diabetes (mother)	3.2	4.1	7.6	2.8	0.8
Asthma	3.2	6.3	10.9	1.3	3.3
Ulcerative Colitis	3.1	4.5	9.0	-0.1	3.0
Knee pain experienced in last month	3.1	4.7	8.6	1.0	2.9
Suffer from ‘nerves’	3.0	4.7	9.2	-3.0	-0.4
Family relationship satisfaction	3.0	3.7	4.5	-1.7	-2.1
Mood swings	3.0	5.4	10.7	0.2	3.3
Major Depression (MDD)	2.9	3.5	6.9	-2.6	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.9	6.1	9.8	-3.1	-1.6
Diabetes (father)	2.8	3.5	7.0	2.6	-0.1
Frequency of tenseness / restlessness in last 2 weeks	2.8	4.4	8.5	-2.9	-0.5
Hearing difficulty/problems with background noise	2.8	4.5	6.9	-2.6	-1.5
Height	2.7	53.0	100.0	10.0	2.5
Average weekly fortified wine intake	2.7	3.2	5.7	-2.4	-0.8
Medication: Ibuprofen	2.7	3.2	5.8	2.4	0.8
Cardiovascular Disease	2.6	8.6	14.2	3.8	1.7
Chronotype (morning person)	2.5	5.8	9.5	3.1	1.4
Medication for hormone replacement therapy	2.5	2.8	4.7	-1.0	-2.2
Birth weight of first child	2.5	4.6	5.5	2.3	1.9
Heart disease (mother)	2.5	3.1	5.3	0.9	2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	3.0	5.4	0.8	2.3
Ulcerative Colitis (UC)	2.4	4.5	8.9	-0.1	3.0
Respiratory disease	2.4	5.4	9.4	1.2	3.1
Lung FEV1/FVC ratio	2.4	12.3	12.7	-3.6	-3.4
Neuroticism score	2.4	4.9	9.8	0.0	3.1
Medication: Ventolin 100micrograms inhaler	2.4	3.0	5.5	0.8	2.3
Alzheimer’s Disease (in mother)	2.3	2.7	2.9	-1.7	-1.6
Neuroticism	2.3	5.6	11.2	-0.0	3.3
Medication: Blood pressure	2.3	4.1	7.6	2.8	0.7
Alzheimer’s Disease (including proxy)	2.2	3.2	5.5	-2.3	-0.9
LDL Cholesterol	2.2	3.4	5.7	-2.4	-1.1
Blood White Count	2.2	16.0	22.7	-3.1	-4.8
Pulse rate	2.2	3.8	5.7	-1.4	-2.4
Standing height	2.2	22.3	44.1	6.6	0.7
Qualifications: College or University degree	2.2	6.8	7.2	-2.7	-2.5
Emphysema/chronic bronchitis	2.2	2.5	4.4	0.8	2.1
Medication: Lisinopril	2.2	2.9	3.5	1.5	1.9
Hypothyroidism/myxoedema (self-reported)	2.1	4.2	7.3	-1.0	-2.7
Ever depressed for a whole week	2.0	2.4	4.8	-2.2	-0.1
Neuroticism (Nagel 2018)	1.9	4.4	7.8	-1.0	2.8
Crohns Disease (2012)	1.9	3.1	6.2	-2.5	-0.2
Medication: Co-codamol	1.9	2.2	2.4	1.5	1.4
Medication: Ramipril	1.9	2.4	4.8	2.2	0.2
Worrier / anxious feelings	1.9	3.5	5.4	-2.3	1.3
Qualifications: A levels/AS levels or equivalent	1.9	4.1	6.2	-1.4	-2.5
Birth weight	1.9	4.1	6.6	2.6	1.3
Chronic bronchitis/emphysema (mother)	1.9	2.2	4.3	-0.3	2.1
Loneliness, isolation	1.9	2.6	3.5	1.9	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.3	4.2	-2.1	-0.5
Hypothyroidism (self reported)	1.8	4.1	7.0	-1.1	-2.6
Leg pain on walking	1.8	2.3	3.0	1.7	1.2
Guilty feelings	1.8	2.6	4.1	2.0	1.1
Severe depression (siblings)	1.7	1.9	3.7	-0.3	1.9
Forced vital capacity (FVC)	1.7	6.6	10.3	3.2	1.7
Time employed in main current job	1.7	1.9	2.5	-1.2	-1.6
Happiness	1.7	2.1	3.0	-1.7	-1.1
Tinnitus: Yes, now most or all of the time	1.7	2.0	2.0	-1.4	-1.4
Diastolic blood pressure, automated reading	1.7	5.3	10.3	3.2	-0.6
Pain experienced in last month	1.7	2.8	4.5	-1.1	-2.1
Neuroticism (2016)	1.6	2.3	2.5	-1.6	1.5
Rheumatoid Arthritis	1.6	2.2	4.1	2.0	0.5
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	3.3	-1.8	-1.0
Systolic blood pressure, automated reading	1.6	4.6	9.2	3.0	-0.2
Ever highly irritable/argumentative for 2 days	1.6	1.9	2.0	1.4	1.3
Waist Hip Ratio (WHR)	1.5	6.5	10.8	3.3	-1.5
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	2.3	-1.1	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.2	4.3	-2.1	0.4
Irritability	1.5	2.5	4.4	0.9	2.1
Exposure to tobacco smoke at home	1.4	1.5	2.4	1.6	0.8
Smoking Status	1.3	3.1	3.6	1.9	1.6
Current tobacco smoking	1.3	2.1	3.9	2.0	0.6
Medication: Levothyroxine sodium	1.3	2.2	4.2	-0.3	-2.1
Had menopause	1.3	1.7	3.3	0.0	-1.8
Hair/balding pattern: Pattern 3	1.3	1.9	2.4	-1.6	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.3	1.5	2.3	-0.8	-1.5
Long-standing illness, disability or infirmity	1.3	2.0	2.2	1.4	1.5
Medication for cholesterol	1.3	1.9	3.8	-2.0	-0.1
Supplements: Calcium	1.3	1.5	2.2	-1.5	-0.8
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	1.9	-1.2	-1.4
Triglycerides	1.2	2.0	3.4	1.8	0.8
Type 2 Diabetes (T2D) (2018)	1.2	2.2	4.1	2.0	0.6
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.3	-0.6	-1.5
Relative age voice broke	1.2	1.8	2.2	-1.5	-1.2
Qualifications: CSEs or equivalent	1.2	1.5	2.0	1.0	1.4
Number of live births	1.2	1.7	2.8	-1.7	-0.8
Illnesses of mother	1.2	1.5	1.8	-1.4	-1.1
Medication: Paracetamol	1.2	2.0	3.4	1.9	0.8
Medication for pain relief, constipation, heartburn	1.2	2.0	3.3	-1.8	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	2.0	-1.0	-1.4
Illnesses of siblings: Diabetes	1.2	1.4	1.6	1.3	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.2	2.0	3.7	-0.5	1.9
Smoking status: Current	1.2	2.0	3.8	1.9	0.4
Average weekly champagne plus white wine intake	1.2	1.7	3.0	-1.7	-0.6
Eye problems/disorders: Glaucoma	1.2	1.5	2.9	1.7	0.2
Mean Putamen Volume	1.1	1.3	1.9	0.8	1.4
Systolic Blood Pressure	1.1	5.4	10.4	3.2	-0.6
Taking other prescription medications	1.1	1.7	2.7	0.8	1.6
Serious illness, injury or assault to yourself	1.1	1.3	2.6	1.6	-0.2
Crohns Disease (2017)	1.0	2.1	3.9	-2.0	-0.5
Relative age of first facial hair	1.0	2.0	2.8	-1.7	-1.1
Supplements: Glucosamine	1.0	1.3	1.4	1.2	1.0
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	2.4	-1.5	0.2
Mother’s age at death	1.0	1.3	2.4	-0.5	-1.5
Irritable Bowel Disease (IBD)	0.9	2.1	2.4	-1.4	1.5
Allergy or Eczema	0.9	2.3	4.3	-2.1	-0.6
Multivitamins +/- minerals	0.9	1.1	2.2	1.5	0.2
Past tobacco smoking	0.9	1.6	2.0	-1.4	-1.1
Pain all over the body in last month	0.9	1.0	1.4	1.2	0.7
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	1.5	-1.2	1.0
Glaucoma (self-reported)	0.9	1.0	1.2	1.1	0.9
Hearing aid user	0.9	1.1	1.2	1.0	-1.1
Illnesses of father: High blood pressure	0.9	1.1	1.3	1.1	1.0
Depression (Nagel 2018)	0.8	1.2	2.4	-1.5	0.2
Number of treatments/medications taken	0.8	1.4	2.4	1.6	0.6
Medication: Atenolol	0.8	1.0	1.4	1.2	-0.7
Alcohol usually taken with meals	0.8	1.3	2.2	1.5	0.6
Forced expiratory volume in 1-second (FEV1)	0.8	2.6	4.1	2.0	1.0
Medication: Cholesterol lowering	0.8	1.2	2.2	-0.5	-1.5
Medication: Lansoprazole	0.8	0.9	1.7	0.3	1.3
Exposure to tobacco smoke outside home	0.8	1.1	1.9	-1.4	-0.5
Average weekly red wine intake	0.8	1.2	2.3	-0.3	-1.5
High cholesterol (Self-reported)	0.8	1.3	2.4	-0.5	-1.6
Myopia	0.8	1.1	1.6	-1.2	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	1.5	-0.6	1.2
Age at First Birth	0.7	1.0	1.4	-1.2	-0.7
Angina	0.7	0.9	1.3	0.7	1.1
Medication: Metformin	0.7	1.0	2.0	1.4	0.3
Prospective memory result	0.7	0.8	1.5	-0.3	-1.2
Blood clot in the leg (DVT)	0.7	0.9	1.3	-0.7	-1.1
Forced vital capacity (FVC), Best measure	0.7	2.6	4.7	2.2	0.6
Mean time to correctly identify matches	0.7	1.3	2.1	-1.4	-0.8
Osteoarthritis (self-reported)	0.7	0.9	1.6	0.5	1.3
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.6	-0.4	-1.3
Intelligence (Savage-Jansen 2018)	0.6	1.7	2.8	1.7	0.8
Fasting Glucose	0.6	0.7	0.9	-0.7	-0.9
Frequency of depressed mood in last 2 weeks	0.6	0.8	1.5	-0.2	1.2
Qualifications: None of the above	0.6	1.3	2.5	0.2	1.6
Heart attack	0.6	0.8	1.4	-0.3	-1.2
Falls in the last year	0.6	0.8	1.5	-0.3	-1.2
Headache pain in last month	0.6	1.1	1.7	0.6	1.3
Shortness of breath walking on level ground	0.6	0.7	1.3	0.3	1.1
Pulse rate, automated reading	0.6	2.0	3.8	-0.5	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	2.2	1.5	0.3
Back pain experienced in last month	0.6	0.9	1.6	0.4	1.3
Ever taken oral contraceptive pill	0.6	0.6	0.8	0.7	0.9
Ever smoked	0.6	1.0	1.5	1.2	0.6
Average weekly beer plus cider intake	0.6	0.9	1.2	-1.1	-0.7
Cholesterol lowering medication	0.6	0.9	1.6	0.5	-1.3
Alcohol drinker status: Previous	0.6	0.7	0.9	0.9	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	2.1	-1.5	-0.5
Fluid intelligence score	0.5	1.0	1.7	0.6	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	0.7	0.7	-0.8
Lung cancer (father)	0.5	0.6	0.9	0.9	0.6
Age at last live birth	0.5	0.7	1.3	-0.0	-1.1
Qualifications: nursing, teaching	0.5	0.8	1.5	0.0	-1.2
Wears glasses or contact lenses	0.5	0.6	1.1	1.1	0.1
Pack years of smoking	0.5	0.8	1.5	0.1	-1.2
Verbal and Numeric Reasoning (VNR)	0.4	1.0	1.5	0.8	1.2
HbA1C	0.4	0.5	0.7	0.5	-0.8
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.0	0.2	-1.0
Stomach or abdominal pain in last month	0.4	0.6	1.1	-1.0	0.2
Sitting height	0.4	2.9	3.6	1.5	-1.9
Medication: Simvastatin	0.4	0.5	0.9	-0.3	-1.0
Pulse wave Arterial Stiffness index	0.4	0.5	0.9	0.9	0.3
Length of working week for main job	0.4	0.5	0.5	0.7	0.7
Number of full brothers	0.4	0.5	0.9	0.3	-0.9
Health satisfaction	0.4	0.5	0.9	0.3	-0.9
Angina (self-reported)	0.4	0.5	0.8	0.4	0.9
Medication: Omeprazole	0.4	0.4	0.6	-0.5	0.8
Medication: Seretide 50 evohaler	0.4	0.4	0.5	0.6	0.7
Chest pain or discomfort	0.4	0.6	0.9	-0.4	-1.0
Illnesses of father: Heart disease	0.4	0.5	1.1	0.0	-1.0
Handedness (chirality/laterality): Left-handed	0.4	0.4	0.8	0.9	-0.2
Medication: Gliclazide	0.4	0.5	1.0	1.0	-0.1
Unable to work because of sickness or disability	0.4	0.5	0.8	0.4	0.9
Alzheimer’s Disease (in father)	0.3	0.3	0.5	-0.7	-0.3
HDL Cholesterol	0.3	0.4	0.7	-0.8	0.4
Hearing difficulty/problems: Yes	0.3	0.4	0.5	-0.6	-0.7
Pack years adult smoking proportion	0.3	0.5	0.8	0.4	-0.9
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.0	-1.0	0.6
Chronic bronchitis/emphysema (father)	0.3	0.3	0.5	0.2	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	1.6	-1.2	0.2
Allergy	0.3	0.7	1.0	0.6	-1.0
Father’s age at death	0.3	0.4	0.5	-0.4	-0.7
Breastfed as a baby	0.3	0.4	0.7	-0.8	-0.3
Loud music exposure frequency	0.3	0.3	0.6	-0.3	0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.0	-1.0	0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.7	-0.9	0.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.7	-0.8	0.6
Worry too long after embarrassment	0.3	0.6	0.9	-0.9	0.4
Migraine (self-reported)	0.3	0.3	0.6	-0.8	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.4	-0.4	0.7
Commuting to job workplace: Walk	0.3	0.4	0.6	-0.3	-0.8
Illnesses of father: None of the above (group 1)	0.3	0.3	0.6	-0.2	0.8
Medication: Paracetamol	0.3	0.4	0.9	0.9	-0.2
Medication: Atorvastatin	0.3	0.4	0.6	-0.3	-0.8
Alcohol drinker status: Never	0.3	0.4	0.5	0.7	-0.6
Reaction Time	0.2	0.4	0.6	-0.8	0.4
Prostate Cancer	0.2	0.3	0.5	-0.4	-0.7
Tanning	0.2	2.3	4.6	-2.1	0.2
Average weekly spirits intake	0.2	0.2	0.4	-0.6	-0.0
Sensitivity / hurt feelings	0.2	0.4	0.4	-0.6	0.6
Supplements: Zinc	0.2	0.2	0.4	-0.6	-0.4
Townsend deprivation index at recruitment	0.2	0.3	0.3	0.5	0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.3	-0.6	0.1
Diabetes (self-reported)	0.2	0.3	0.5	0.7	-0.3
Illnesses of siblings	0.2	0.3	0.4	-0.6	0.4
Hair/balding pattern: Pattern 4	0.2	0.5	1.0	-0.1	1.0
Age at first live birth	0.2	0.4	0.6	0.5	-0.7
Smoking status: Previous	0.2	0.3	0.4	0.4	0.6
Diabetes diagnosed by doctor	0.2	0.4	0.8	0.9	-0.1
Breast cancer (self-reported)	0.2	0.3	0.4	0.3	0.6
Commuting to job workplace: Public transport	0.2	0.3	0.3	0.4	-0.6
Number of operations (self-reported)	0.2	0.3	0.3	0.5	0.5
Risk taking	0.2	0.2	0.3	0.5	0.5
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.3	0.2	-0.6
Heart disease (siblings)	0.2	0.2	0.4	0.2	-0.6
Breast Cancer	0.1	0.2	0.3	0.5	0.3
Ovarian Cancer	0.1	0.2	0.2	-0.4	0.4
Lupus	0.1	0.2	0.4	-0.6	-0.1
Blood Platelet Count	0.1	1.5	2.0	-1.4	-1.0
Lung FVC	0.1	0.3	0.5	-0.7	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.2	0.2	0.4
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	0.3	-0.2
Hair/balding pattern: Pattern 2	0.1	0.1	0.1	-0.4	-0.2
Noisy workplace	0.1	0.2	0.3	-0.1	0.5
Depression (self-reported)	0.1	0.1	0.2	-0.4	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.3	0.3	-0.5
Medication: Amlodipine	0.1	0.1	0.2	0.5	-0.1
Pulse wave peak to peak time	0.1	0.1	0.1	-0.4	-0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.2	-0.1	0.5
Medication: Allopurinol	0.1	0.1	0.1	-0.2	0.3
Overall health rating	0.1	0.2	0.3	0.5	0.4
Had major operations	0.1	0.2	0.3	-0.5	0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.2	-0.5	0.3
Friendships satisfaction	0.1	0.1	0.1	-0.1	0.4
Mineral and other dietary supplements	0.1	0.1	0.2	-0.2	-0.5
Financial situation satisfaction	0.1	0.1	0.1	0.3	-0.2
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.3	0.1	0.5
Schizophrenia vs Biploar Disorder	0.0	0.1	0.1	0.2	0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.0	0.1	-0.1	0.3
Vitamin and mineral supplements	0.0	0.0	0.0	-0.0	0.2
Had other major operations	0.0	0.1	0.1	0.3	0.1
Financial difficulties in last 2 years	0.0	0.1	0.1	0.4	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.1	0.2	0.1	0.4
Peak expiratory flow (PEF)	0.0	0.0	0.1	0.3	-0.2
Gout (self-reported)	0.0	0.0	0.0	0.0	0.1
High blood pressure (siblings)	0.0	0.1	0.1	0.4	0.0
Number of full sisters	0.0	0.0	0.0	-0.2	0.1
Ever had bowel cancer screening	0.0	0.0	0.1	0.1	-0.3
Osteoporosis (self-reported)	0.0	0.0	0.0	0.0	-0.0
Number of self-reported non-cancer illnesses	0.0	0.1	0.1	-0.3	-0.2
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	0.2	-0.0
Fractured/broken bones in last 5 years	0.0	0.0	0.1	-0.3	0.1
Age started oral contraceptive pill	0.0	0.0	0.0	-0.1	-0.1
Commuting to job workplace: Cycle	0.0	0.0	0.1	-0.3	-0.0

Hub : Genes

SLX1A-SULT1A3

Models

Trait associations