Hub : Genes

SMARCAD1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 YFS Blood 0.0204 0.0074 5.1e-06 0.013 0.017 0.016 0.017 0.017 3.5e-05 1.6e-06 3.6e-06 2.1e-06 2.0e-06
2 TCGA Brain Lower Grade Glioma 0.0578 0.0413 3.3e-04 0.038 0.026 0.021 NA 0.034 3.8e-05 5.1e-04 1.7e-03 NA 9.2e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 1.1 1.8 3.0 -0.7 1.7
Bipolar Disorder or Schizophrenia 1.6 3.9 6.8 -1.0 2.6
Depressed Affect (Nagel 2018) 1.1 2.3 3.4 -1.8 -1.1
Depression (Nagel 2018) 0.1 0.2 0.3 -0.4 -0.5
Intelligence (Savage-Jansen 2018) 0.7 2.1 3.7 -0.7 -1.9
Neuroticism (Nagel 2018) 1.2 2.8 5.0 -2.2 -0.8
Schizophrenia (2018) 1.0 2.1 3.8 -0.7 1.9
Schizophrenia vs Biploar Disorder 1.1 1.4 2.3 0.7 1.5
Worry (Nagel 2018) 0.8 1.7 3.4 -1.8 -0.0
Alzheimer’s Disease (in mother) 0.1 0.1 0.3 0.5 -0.2
Alzheimer’s Disease (in father) 0.2 0.2 0.5 0.1 -0.7
Alzheimer’s Disease (including proxy) 0.2 0.3 0.4 0.7 -0.4
Crohns Disease (2017) 1.9 4.2 7.5 0.9 2.7
Irritable Bowel Disease (IBD) 2.1 5.1 10.1 0.3 3.2
Ulcerative Colitis (UC) 0.5 0.8 1.6 -0.3 1.3
Major Depression (MDD) 0.5 0.6 1.1 -1.0 0.3
Reaction Time 1.3 2.5 5.0 0.1 -2.2
Verbal and Numeric Reasoning (VNR) 0.9 2.1 4.2 -0.2 -2.0
Breast Cancer 1.2 2.9 5.5 -0.5 2.3
Ovarian Cancer 1.0 1.4 2.6 0.4 -1.6
Prostate Cancer 0.9 1.3 2.5 0.4 1.6
Age at First Birth 0.2 0.2 0.2 0.5 -0.5
Bipolar Disorder (2011) 3.4 3.3 5.0 -1.2 2.2
Body Mass Index (BMI) (2010) 1.0 1.4 2.7 0.2 -1.6
Coronary Artery Disease (CAD) 0.3 0.4 0.8 -0.9 -0.0
Crohns Disease (2012) 3.9 6.3 12.5 -0.2 3.5
Mean Putamen Volume 0.4 0.5 0.9 0.3 0.9
Fasting Glucose 1.9 2.3 2.9 1.7 -1.3
HbA1C 0.6 0.7 1.1 1.1 -0.5
HDL Cholesterol 1.3 2.2 4.3 -0.2 -2.1
LDL Cholesterol 1.4 2.3 3.9 -0.8 2.0
Lupus 1.1 1.7 2.8 0.8 1.7
Neuroticism (2016) 0.3 0.4 0.4 -0.6 -0.6
Primary Biliary Cirrhosis 1.5 2.2 3.6 -1.9 0.9
Rheumatoid Arthritis 1.6 2.2 3.6 -1.9 0.9
Schizophrenia (2014) 2.1 4.6 8.2 -1.0 2.9
Triglycerides 1.4 2.4 4.5 0.5 2.1
Type 2 Diabetes (T2D) (2012) 2.5 2.8 5.0 -0.8 -2.2
Ulcerative Colitis 0.3 0.4 0.8 -0.9 -0.3
Blood Eosinophil Count 0.6 4.4 7.8 -2.8 1.0
Blood Platelet Count 0.8 9.6 12.7 3.6 -2.5
Blood Red Count 0.3 3.1 4.2 1.4 2.0
Blood White Count 0.0 0.1 0.1 0.3 -0.2
Heel T-Score 10.6 84.5 94.5 8.6 9.7
BMI 2.1 12.4 18.9 -2.4 -4.4
Height 0.3 6.3 8.4 2.0 2.9
Waist Hip Ratio (WHR) 1.1 4.8 9.6 3.1 -0.2
Systolic Blood Pressure 0.7 3.3 6.5 2.5 0.3
Smoking Status 0.2 0.5 0.7 0.8 -0.6
Allergy or Eczema 0.1 0.2 0.3 0.6 0.1
Cardiovascular Disease 1.9 6.2 9.2 1.7 -3.0
Hypothyroidism (self reported) 0.1 0.3 0.4 0.4 -0.7
Respiratory disease 1.1 2.4 4.8 -0.2 -2.2
Type 2 Diabetes (T2D) (2018) 1.6 2.9 5.7 0.4 -2.4
Lung FEV1/FVC ratio 0.9 4.7 8.1 2.8 -1.2
Lung FVC 0.2 0.8 1.4 0.5 -1.2
Neuroticism 2.5 6.1 12.3 -3.5 0.1
Chronotype (morning person) 0.2 0.5 0.9 -1.0 0.2
Hair Pigment 0.0 0.6 1.2 -1.1 -0.1
Tanning 0.0 0.5 1.0 1.0 -0.1
Hand grip strength (left) 1.0 2.5 2.8 -1.5 1.7
Number of treatments/medications taken 0.3 0.5 0.7 0.6 -0.8
Average weekly spirits intake 0.4 0.6 1.1 -0.1 1.1
Sensitivity / hurt feelings 1.2 2.1 4.3 -2.1 0.1
Frequency of depressed mood in last 2 weeks 0.6 0.8 1.7 0.1 -1.3
Hearing difficulty/problems: Yes 0.3 0.5 1.0 -0.0 -1.0
Relative age of first facial hair 7.4 15.2 18.9 -4.4 3.4
Other serious medical condition/disability diagnosed by doctor 1.3 1.7 3.4 -0.1 -1.8
Ever used hormone-replacement therapy (HRT) 0.2 0.2 0.4 -0.6 -0.2
Ever had hysterectomy (womb removed) 2.2 2.5 3.2 -1.8 -1.4
Systolic blood pressure, automated reading 0.7 2.0 4.0 2.0 -0.1
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.4 0.6 -0.2
Angina 1.2 1.6 2.1 1.5 1.0
Medication for hormone replacement therapy 0.9 1.0 1.5 1.2 0.8
Vitamin and mineral supplements 0.0 0.0 0.1 0.3 -0.1
Supplements: Zinc 0.2 0.2 0.4 0.7 -0.1
Medication: Co-codamol 0.8 0.9 0.9 1.0 -0.9
Medication: Metformin 0.0 0.1 0.1 0.3 0.1
Diabetes (father) 0.4 0.4 0.9 -0.0 0.9
Diabetes (mother) 1.4 1.8 2.8 0.9 -1.7
Severe depression (siblings) 0.2 0.2 0.4 0.0 -0.6
Pack years adult smoking proportion 2.6 3.9 7.7 2.8 -0.4
Impedance of leg (right) 3.0 14.4 24.1 4.9 2.2
Leg fat-free mass (left) 1.5 7.8 8.1 -2.9 -2.7
Trunk fat percentage 0.8 3.3 4.0 2.0 -1.6
Hand grip strength (right) 1.1 2.9 3.6 -1.9 1.5
Townsend deprivation index at recruitment 0.2 0.2 0.5 0.7 0.0
Current tobacco smoking 1.9 3.1 4.9 2.2 -1.1
Average weekly fortified wine intake 0.1 0.1 0.2 0.2 -0.4
Maternal smoking around birth 0.8 1.1 2.3 0.0 1.5
Fed-up feelings 2.2 3.9 4.5 -2.1 -1.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 0.7 0.3 -0.8
Relative age voice broke 10.5 16.0 18.2 -4.3 3.7
Taking other prescription medications 0.8 1.2 1.9 1.4 0.7
Age when periods started (menarche) 8.3 19.9 24.0 -4.0 4.9
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.1 0.0 -0.4
Heel bone mineral density (BMD) T-score, automated (left) 3.3 7.5 8.7 2.5 3.0
Tinnitus: Yes, but not now, but have in the past 1.2 1.2 1.6 1.3 -0.9
Qualifications: CSEs or equivalent 0.4 0.5 0.9 0.9 -0.3
Serious illness, injury or assault to yourself 0.6 0.7 1.0 -1.0 0.6
High blood pressure 1.4 3.9 4.0 2.0 -2.0
Hayfever, allergic rhinitis or eczema 0.3 0.7 1.3 1.1 0.2
Multivitamins +/- minerals 0.0 0.1 0.1 0.2 -0.3
Stomach or abdominal pain in last month 0.3 0.4 0.6 0.4 0.7
Supplements: Glucosamine 0.0 0.0 0.0 0.1 0.1
Diverticular disease/diverticulitis (self-reported) 4.0 4.8 6.6 1.7 -2.6
Medication: Atenolol 0.7 0.9 1.7 0.4 -1.3
Medication: Levothyroxine sodium 0.5 0.8 1.6 1.3 -0.1
Sitting height 0.5 3.6 6.2 2.5 1.0
Chronic bronchitis/emphysema (father) 4.2 4.9 7.7 1.4 -2.8
High blood pressure (mother) 1.0 1.5 1.6 1.3 -1.2
Body mass index (BMI) 2.0 8.4 14.8 -1.4 -3.8
Impedance of leg (left) 2.9 14.1 26.0 5.1 1.5
Leg predicted mass (left) 1.5 7.8 7.8 -2.8 -2.8
Trunk fat mass 0.8 3.6 6.1 1.1 -2.5
Waist circumference 1.8 6.6 13.2 -0.1 -3.6
Number of incorrect matches in round 1.4 2.3 4.0 -0.8 2.0
Past tobacco smoking 0.0 0.0 0.1 0.1 -0.2
Alcohol usually taken with meals 0.4 0.6 0.7 -0.8 0.7
Nervous feelings 0.0 0.1 0.1 -0.2 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.0 0.1 0.1 -0.1 -0.3
Hearing difficulty/problems with background noise 1.5 2.4 3.7 1.1 -1.9
Hair/balding pattern: Pattern 2 0.2 0.3 0.4 -0.3 0.7
Had menopause 0.2 0.3 0.3 -0.5 0.5
Had other major operations 1.5 1.8 3.3 -0.6 -1.8
Forced vital capacity (FVC) 0.1 0.3 0.5 0.4 -0.7
Heel bone mineral density (BMD) T-score, automated (right) 4.1 9.5 9.9 3.1 3.0
Ever unenthusiastic/disinterested for a whole week 0.2 0.2 0.3 -0.6 0.4
Qualifications: None of the above 3.2 6.8 9.6 3.1 -2.0
Financial difficulties in last 2 years 2.1 2.8 3.5 -1.9 -1.5
Mouth/teeth dental problems 2.6 4.0 5.2 -2.3 1.7
Heart attack 1.4 1.8 3.0 0.8 1.7
Allergy 0.4 0.9 0.9 -1.0 1.0
Pain all over the body in last month 0.6 0.7 1.1 1.0 -0.5
Diabetes (self-reported) 0.2 0.3 0.6 0.0 -0.8
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 1.6 1.3 0.1
Medication: Ramipril 2.3 3.0 5.9 2.4 0.1
Medication: Simvastatin 2.9 4.3 7.5 2.7 1.1
Fluid intelligence score 0.0 0.1 0.1 -0.4 0.1
Illnesses of siblings 1.2 1.7 2.8 -0.8 1.7
Neuroticism score 2.3 4.8 9.6 -3.1 0.3
Weight 1.2 6.1 10.7 -1.2 -3.3
Impedance of arm (right) 3.8 17.6 21.3 3.7 4.6
Arm fat percentage (right) 0.6 2.5 4.9 0.4 -2.2
Trunk fat-free mass 1.4 8.2 8.2 -2.9 -2.9
Hip circumference 2.0 8.8 12.7 -2.2 -3.6
Time employed in main current job 0.2 0.2 0.4 0.6 0.2
Alcohol intake versus 10 years previously 0.5 0.7 0.9 1.0 0.7
Father’s age at death 0.7 0.9 1.2 -1.1 -0.8
Worrier / anxious feelings 0.4 0.7 1.1 -0.5 -1.0
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 0.8 0.4 -0.9
Falls in the last year 0.1 0.1 0.2 -0.4 -0.1
Hair/balding pattern: Pattern 3 0.0 0.0 0.0 -0.2 -0.0
Number of live births 0.4 0.5 0.6 0.8 -0.6
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 1.2 0.4 -1.1
Pulse rate 1.2 2.0 2.9 1.0 -1.7
Happiness 6.6 8.0 15.2 -3.9 -0.9
Noisy workplace 0.2 0.2 0.4 0.2 -0.6
Qualifications: A levels/AS levels or equivalent 0.0 0.0 0.1 -0.3 -0.1
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 1.0 0.5 -1.0
Mouth/teeth dental problems: Dentures 2.2 3.7 6.5 2.5 -1.0
Asthma 1.3 2.5 3.9 -1.1 -2.0
Medication: Ibuprofen (e.g. Nurofen) 2.3 2.9 5.7 -2.4 -0.2
Medication: Cholesterol lowering 0.9 1.5 2.8 1.7 0.4
Depression (self-reported) 0.1 0.1 0.2 -0.3 -0.4
Medication: Lansoprazole 0.5 0.6 1.2 -0.1 1.1
Prospective memory result 1.9 2.4 2.5 1.5 -1.6
Lung cancer (father) 1.3 1.6 3.1 -1.8 0.2
Illnesses of mother 0.3 0.3 0.5 -0.7 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 0.3 0.2 -0.6
Pulse wave Arterial Stiffness index 0.1 0.1 0.1 0.1 -0.3
Impedance of arm (left) 4.1 19.2 23.8 3.8 4.9
Arm fat mass (right) 1.1 4.7 9.4 -0.3 -3.1
Trunk predicted mass 1.4 8.0 8.2 -2.9 -2.8
Standing height 0.1 0.6 1.2 0.2 1.1
Length of working week for main job 0.0 0.0 0.1 -0.1 -0.3
Exposure to tobacco smoke at home 0.6 0.7 0.9 1.0 0.7
Breastfed as a baby 0.2 0.3 0.4 0.4 -0.7
Tense / ‘highly strung’ 1.9 3.1 3.2 -1.8 1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.6 3.2 -1.8 -0.2
Hair/balding pattern: Pattern 4 1.9 4.5 7.3 2.7 1.3
Birth weight of first child 0.9 1.6 2.1 1.4 -1.1
Peak expiratory flow (PEF) 3.0 7.0 7.2 -2.7 -2.6
Pulse wave reflection index 0.1 0.2 0.3 -0.5 -0.2
Ever highly irritable/argumentative for 2 days 0.8 0.9 1.3 -0.7 1.2
Loud music exposure frequency 0.3 0.3 0.6 -0.8 -0.1
Qualifications: O levels/GCSEs or equivalent 1.0 1.6 2.7 -0.8 1.6
Mouth/teeth dental problems: Bleeding gums 0.5 0.7 1.1 0.5 1.0
Blood clot in the leg (DVT) 0.1 0.1 0.2 0.1 0.4
Medication: Paracetamol 1.2 1.9 3.2 0.8 -1.8
Headache pain in last month 0.1 0.2 0.3 -0.1 -0.6
Medication for cholesterol, blood pressure or diabetes 1.7 2.8 5.6 -2.4 0.0
Glaucoma (self-reported) 2.7 3.2 4.0 2.0 1.5
Gout (self-reported) 1.5 2.1 2.4 -1.4 -1.5
Hypothyroidism/myxoedema (self-reported) 0.8 1.5 3.0 1.7 -0.1
Medication: Amlodipine 2.5 3.5 5.2 2.3 -1.4
Medication: Ventolin 100micrograms inhaler 1.0 1.2 1.9 1.4 -0.8
Birth weight 0.7 1.6 3.0 1.7 0.4
Chronic bronchitis/emphysema (mother) 0.0 0.1 0.1 -0.1 0.3
High blood pressure (siblings) 1.0 1.5 2.5 0.7 -1.6
Forced vital capacity (FVC), Best measure 0.0 0.2 0.3 0.6 0.1
Body fat percentage 1.0 3.8 4.7 1.7 -2.2
Leg fat percentage (right) 1.5 5.4 8.5 1.5 -2.9
Arm fat-free mass (right) 1.7 8.7 11.2 -2.5 -3.4
Exposure to tobacco smoke outside home 1.5 2.1 3.4 0.8 -1.8
Comparative body size at age 10 0.7 2.0 2.3 1.3 -1.5
Number of full brothers 0.0 0.0 0.0 -0.2 -0.2
Worry too long after embarrassment 2.2 3.7 7.3 -2.7 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 1.3 1.7 3.1 -1.8 -0.5
Wheeze or whistling in the chest in last year 4.5 8.0 9.1 2.6 -3.0
Number of children fathered 0.5 0.5 0.9 0.9 0.4
Reason for reducing amount of alcohol drunk: Health precaution 2.5 2.9 4.0 -1.3 -2.0
Age at first live birth 0.2 0.3 0.4 0.5 0.7
Pulse wave peak to peak time 0.1 0.2 0.3 -0.1 0.6
Health satisfaction 1.1 1.4 2.8 -1.7 -0.3
Shortness of breath walking on level ground 0.7 0.9 1.3 1.1 0.6
Qualifications: College or University degree 2.6 8.1 15.0 -3.9 1.1
Eye problems/disorders: None of the above 0.3 0.3 0.4 -0.5 -0.6
Mouth/teeth dental problems: Loose teeth 1.8 2.2 3.1 1.1 -1.8
Emphysema/chronic bronchitis 0.1 0.1 0.2 0.4 -0.2
Medication for pain relief, constipation, heartburn 0.2 0.3 0.4 -0.3 0.7
Neck or shoulder pain in last month 0.0 0.0 0.0 -0.2 -0.1
Medication: Blood pressure 2.5 4.5 8.7 2.9 0.6
Angina (self-reported) 1.4 1.8 2.3 1.5 1.2
Migraine (self-reported) 1.5 1.8 3.1 -1.8 -0.7
Medication: Ibuprofen 2.7 3.2 6.4 -2.5 -0.1
Medication: Allopurinol 1.4 1.9 2.9 -0.9 -1.7
Medication: Omeprazole 1.0 1.2 1.6 -1.2 -0.9
Medication: Seretide 50 evohaler 0.5 0.6 0.6 0.8 -0.7
Mean time to correctly identify matches 1.0 2.0 3.8 0.5 -1.9
Heart disease (mother) 2.1 2.6 3.5 1.9 1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.4 0.7 -0.4 -0.8
Whole body fat mass 1.0 4.3 8.2 0.6 -2.9
Leg fat mass (right) 1.9 7.4 14.3 0.7 -3.8
Arm predicted mass (right) 1.7 8.7 11.8 -2.3 -3.4
Pulse rate, automated reading 2.3 7.3 14.0 0.8 -3.7
Alcohol intake frequency. 0.1 0.2 0.3 -0.0 -0.6
Comparative height size at age 10 1.8 10.1 12.2 3.5 -2.8
Number of full sisters 0.4 0.4 0.8 -0.9 -0.2
Suffer from ‘nerves’ 1.1 1.7 3.2 0.4 -1.8
Overall health rating 2.0 4.4 4.4 2.1 -2.1
Chest pain or discomfort 1.0 1.4 2.2 1.5 -0.8
Had major operations 0.2 0.3 0.4 -0.7 0.3
Age at last live birth 0.0 0.1 0.1 -0.2 -0.3
Family relationship satisfaction 1.2 1.5 1.5 -1.2 -1.2
Leg pain on walking 0.3 0.3 0.4 0.6 -0.6
Qualifications: NVQ or HND or HNC or equivalent 1.2 1.5 2.0 -1.4 0.9
Commuting to job workplace: Car/motor vehicle 0.8 0.9 1.3 -1.1 0.7
Illness, injury, bereavement, stress in last 2 years 3.6 4.4 4.6 2.0 2.1
Medication: Aspirin 2.3 3.0 6.0 2.4 0.3
Supplements: Vitamin C 0.0 0.0 0.0 -0.2 -0.1
Knee pain experienced in last month 0.0 0.1 0.1 -0.3 0.2
Hypertension (Self-reported) 2.0 5.5 7.1 2.0 -2.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.1 2.2 -1.5 0.1
Illnesses of father: Heart disease 0.2 0.3 0.5 0.4 0.7
Illnesses of siblings: Diabetes 0.2 0.2 0.3 -0.3 -0.6
Smoking status: Previous 0.3 0.4 0.6 -0.8 0.4
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.6 1.8 1.3 1.2
Whole body fat-free mass 1.6 9.1 9.6 -2.9 -3.1
Leg fat-free mass (right) 1.7 9.0 9.5 -3.1 -2.9
Arm fat percentage (left) 0.6 2.5 4.8 0.4 -2.2
Average weekly red wine intake 2.9 4.3 6.9 -2.6 1.3
Handedness (chirality/laterality): Left-handed 2.1 2.5 4.7 -2.2 -0.5
Mood swings 0.5 0.9 1.7 0.1 -1.3
Loneliness, isolation 1.2 1.6 1.9 -1.1 -1.4
Long-standing illness, disability or infirmity 0.6 0.9 1.7 1.3 -0.4
Ever had bowel cancer screening 2.5 3.0 5.0 1.0 -2.2
Diabetes diagnosed by doctor 0.5 0.8 1.6 -0.1 -1.3
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.1 -0.3 0.3
Friendships satisfaction 3.5 4.4 7.9 -2.8 0.9
Qualifications: nursing, teaching 0.1 0.1 0.2 -0.2 0.5
Commuting to job workplace: Walk 2.5 2.7 3.5 1.4 -1.9
Eye problems/disorders: Cataract 0.9 1.0 2.0 1.4 0.3
Mouth/teeth dental problems: Mouth ulcers 3.3 5.2 10.2 -0.3 -3.2
Medication for cholesterol 1.5 2.2 3.6 -1.9 0.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.2 0.5 0.1
Back pain experienced in last month 2.0 3.0 4.2 1.3 -2.1
Mineral and other dietary supplements 0.3 0.4 0.7 0.0 -0.9
Breast cancer (self-reported) 1.2 1.4 2.6 -0.5 -1.6
Asthma (self-reported) 1.4 2.8 3.9 -1.3 -2.0
Osteoporosis (self-reported) 0.7 0.9 1.6 0.4 -1.3
Osteoarthritis (self-reported) 1.1 1.4 2.5 -0.5 -1.6
Medication: Aspirin 2.2 2.8 5.6 2.4 0.1
Medication: Gliclazide 0.4 0.5 1.0 -0.0 1.0
Illnesses of father: None of the above (group 1) 2.2 2.7 5.0 -0.6 2.2
Smoking status: Current 1.8 2.9 4.5 2.1 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 0.2 -0.4 -0.4
Whole body water mass 1.7 9.7 10.2 -3.0 -3.2
Leg predicted mass (right) 1.7 9.1 9.5 -3.1 -3.0
Arm fat mass (left) 1.2 4.9 9.7 -0.3 -3.1
Number of self-reported non-cancer illnesses 1.5 2.7 3.5 -1.3 -1.9
Average weekly champagne plus white wine intake 1.7 2.4 4.5 2.1 0.5
Miserableness 0.9 1.6 3.1 -1.8 -0.2
Guilty feelings 0.4 0.7 0.9 -0.7 0.9
Wears glasses or contact lenses 1.5 1.7 3.3 0.3 -1.8
Ever taken oral contraceptive pill 2.3 2.6 5.2 -2.3 -0.1
Hearing aid user 2.0 2.2 2.3 1.5 -1.5
Mother’s age at death 1.3 1.6 3.2 -1.8 0.1
Financial situation satisfaction 0.2 0.2 0.3 -0.3 0.5
Tinnitus: Yes, now most or all of the time 0.3 0.3 0.5 -0.7 0.4
Commuting to job workplace: Public transport 0.3 0.3 0.6 0.3 -0.8
Eye problems/disorders: Glaucoma 2.8 3.3 5.6 2.4 1.0
Medication: Blood pressure 2.2 4.2 7.4 1.0 -2.7
Pain type(s) experienced in last month: Hip pain 2.1 2.7 5.2 0.4 -2.3
Supplements: Fish oil (including cod liver oil) 0.9 1.1 2.1 -1.4 0.4
High cholesterol (Self-reported) 0.8 1.3 2.0 1.4 0.8
Medication: Bendroflumethiazide 1.2 1.8 2.2 1.5 -1.2
Medication: Paracetamol 1.0 1.5 2.3 0.8 -1.5
Medication: Lisinopril 0.4 0.6 1.0 -0.4 1.0
Medication: Atorvastatin 1.9 2.4 3.3 1.2 -1.8
Illnesses of father: High blood pressure 3.5 4.4 4.7 2.0 -2.2
Alcohol drinker status: Never 0.1 0.1 0.1 0.3 0.3
Ever smoked 0.2 0.3 0.6 0.8 0.1
Basal metabolic rate 1.6 8.7 10.8 -2.6 -3.3
Leg fat percentage (left) 1.8 6.6 10.6 1.6 -3.3
Arm fat-free mass (left) 1.9 9.6 13.6 -2.4 -3.7
Number of operations (self-reported) 2.1 3.1 3.8 -1.5 -2.0
Average weekly beer plus cider intake 1.2 1.8 3.5 -0.2 -1.9
Irritability 1.2 2.0 2.0 -1.4 1.4
Risk taking 2.6 3.8 7.3 -0.6 2.7
Ever had prostate specific antigen (PSA) test 0.8 0.9 1.8 -1.3 0.2
Fractured/broken bones in last 5 years 0.5 0.6 1.2 0.2 -1.1
Age started oral contraceptive pill 0.4 0.4 0.7 -0.8 0.5
Diastolic blood pressure, automated reading 1.1 3.5 6.7 0.5 -2.6
Ever depressed for a whole week 0.5 0.6 0.8 -0.7 0.9
Unable to work because of sickness or disability 1.1 1.4 2.5 0.6 -1.6
Commuting to job workplace: Cycle 0.3 0.3 0.4 -0.6 0.5
Myopia 1.4 2.1 2.2 1.5 1.4
Vascular/heart problems diagnosed by doctor 1.2 3.4 3.7 -1.8 1.9
Cholesterol lowering medication 1.6 2.3 4.1 2.0 0.7
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 0.9 -0.3 -0.9
Pain experienced in last month 0.3 0.5 0.8 0.4 0.9
Supplements: Calcium 1.5 1.6 3.3 0.1 1.8
Basal cell carcinoma (self-reported) 0.5 0.6 1.1 -1.0 0.5
Heart attack/myocardial infarction (self-reported) 1.4 1.8 2.8 0.9 1.7
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 0.3 0.2 0.5
Heart disease (siblings) 0.7 0.9 1.3 0.6 -1.1
Alcohol drinker status: Previous 1.1 1.3 1.7 -1.3 -0.9
Pack years of smoking 2.1 3.1 6.2 2.5 0.1
Impedance of whole body 3.9 20.1 25.1 5.0 3.9
Leg fat mass (left) 2.1 8.4 16.2 0.8 -4.0
Arm predicted mass (left) 1.8 9.2 13.2 -2.3 -3.6