TWAS hub - SMG5

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1160	0.0330	2.3e-06	0.089	NA	0.091	NA	0.077	1.0e-07	NA	7.0e-08	NA	7.1e-07
2	GTEx	Breast Mammary Tissue	0.1300	0.0440	4.4e-04	0.126	NA	0.114	NA	0.044	5.0e-07	NA	1.8e-06	NA	2.5e-03
3	GTEx	Breast Mammary Tissue (Female)	0.2049	0.0752	3.0e-03	0.145	NA	0.049	NA	0.053	4.3e-05	NA	1.4e-02	NA	1.1e-02
4	GTEx	Cells Transformed fibroblasts	0.1510	0.0490	2.2e-05	0.095	NA	0.096	NA	0.085	1.3e-07	NA	1.2e-07	NA	5.8e-07
5	GTEx	Esophagus Mucosa	0.0730	0.0290	3.6e-03	0.023	NA	0.026	NA	0.032	1.0e-02	NA	6.7e-03	NA	3.0e-03
6	GTEx	Liver	0.3540	0.0870	4.4e-05	0.316	NA	0.325	NA	0.351	1.5e-09	NA	7.9e-10	NA	1.3e-10
7	GTEx	Lung	0.1121	0.0354	1.9e-05	0.108	NA	0.080	NA	0.033	1.3e-08	NA	9.9e-07	NA	1.5e-03
8	GTEx	Nerve Tibial	0.1798	0.0410	1.5e-09	0.196	NA	0.198	NA	0.162	7.3e-14	NA	4.8e-14	NA	1.5e-11
9	GTEx	Spleen	0.3290	0.0870	4.1e-05	0.373	NA	0.363	NA	0.080	1.5e-10	NA	3.2e-10	NA	4.3e-03
10	GTEx	Whole Blood	0.4050	0.0430	0.0e+00	0.496	NA	0.491	NA	0.136	5.2e-52	NA	2.7e-51	NA	1.7e-12
11	METSIM	Adipose	0.1953	0.0318	0.0e+00	0.275	0.256	0.271	0.270	0.278	2.8e-41	4.7e-38	1.5e-40	2.4e-40	9.8e-42
12	NTR	Blood	0.0267	0.0089	3.1e-05	0.024	0.009	0.016	0.008	0.006	3.0e-08	6.1e-04	3.9e-06	7.2e-04	2.9e-03
13	YFS	Blood	0.3416	0.0336	0.0e+00	0.542	0.520	0.541	0.541	0.542	2.4e-216	2.1e-203	7.8e-216	5.9e-216	5.0e-216
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.0368	0.0200	6.6e-04	0.020	0.014	0.019	NA	0.014	2.3e-03	9.1e-03	2.9e-03	NA	9.8e-03
15	TCGA	Prostate Adenocarcinoma	0.0440	0.0254	2.3e-03	0.024	0.020	0.026	NA	0.016	1.5e-03	3.5e-03	8.0e-04	NA	7.7e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Falls in the last year	7.6	10.3	13.3	-3.2	-2.9	-3.2	-2.9	-2.7	-3.2	-3.5	-3.6	-3.3	-3.3	-3.4	-3.3	-3.3	-3.1	-3.0
Mean Putamen Volume	7.0	8.0	10.0	-3.0	-3.0	-2.6	-2.9	-2.0	-3.1	-2.6	-3.0	-3.0	-3.2	-3.1	-3.1	-2.9	-2.8	-1.9
LDL Cholesterol	6.1	9.6	12.8	-3.2	-3.6	-3.0	-3.1	-2.1	-3.4	-2.9	-2.9	-3.2	-3.6	-3.5	-3.4	-3.4	-2.4	-2.3
Maternal smoking around birth	5.4	7.8	10.8	-3.1	-3.3	-2.9	-2.9	-1.5	-3.0	-2.8	-2.2	-3.0	-3.1	-3.0	-3.1	-3.0	-1.3	-3.0
Reason for reducing amount of alcohol drunk: Health precaution	4.8	5.6	9.5	-2.4	-2.5	-2.3	-2.3	-2.2	-3.1	-2.2	-2.3	-2.3	-2.4	-2.7	-2.5	-2.5	-1.7	-1.8
Medication for hormone replacement therapy	4.6	5.2	9.1	-3.0	-1.7	-1.7	-2.8	-3.0	-1.4	-2.6	-1.9	-2.0	-2.1	-2.0	-2.4	-2.4	-2.7	-1.6
Gout (self-reported)	4.5	6.1	8.8	2.8	2.2	2.4	2.5	1.4	2.7	2.0	2.5	2.9	3.0	2.6	2.9	2.7	2.1	2.0
Neck or shoulder pain in last month	4.5	6.4	9.1	-2.7	-2.2	-3.0	-2.2	-1.1	-3.0	-2.9	-2.2	-2.8	-2.8	-2.7	-2.8	-2.9	-1.1	-2.7
Breast Cancer	4.4	10.6	16.2	-3.9	-2.9	-2.5	-3.3	-4.0	-2.9	-3.2	-3.6	-3.5	-2.8	-3.3	-3.1	-3.1	-3.6	-2.6
Primary Biliary Cirrhosis	4.4	6.3	8.5	-2.7	-2.8	-2.8	-2.0	-0.6	-2.9	-2.7	-2.5	-2.7	-2.8	-2.8	-2.6	-2.7	-1.7	-2.4
Number of incorrect matches in round	4.3	7.1	13.1	2.6	3.1	2.9	3.0	2.6	1.8	2.6	2.6	2.7	2.3	2.5	2.4	2.4	2.3	3.6
Ever smoked	4.0	7.1	9.1	-3.0	-2.5	-2.6	-3.0	-2.0	-2.7	-2.8	-2.7	-2.7	-2.8	-2.7	-2.7	-2.7	-2.2	-2.5
Medication: Metformin	3.9	5.5	9.5	-2.4	-2.7	-2.9	-2.1	-0.2	-2.7	-2.6	-1.9	-2.3	-2.3	-2.5	-2.2	-2.5	-1.1	-3.1
Eye problems/disorders: Diabetes related eye disease	3.7	4.1	5.7	-2.2	-2.4	-2.3	-2.0	-1.7	-1.4	-2.3	-1.9	-2.1	-1.7	-2.0	-2.0	-2.1	-1.8	-2.3
Neuroticism (2016)	3.6	5.2	7.2	2.0	2.5	2.6	2.0	0.8	2.3	2.1	2.6	2.6	2.5	2.6	2.7	2.5	1.4	2.2
Ever used hormone-replacement therapy (HRT)	3.6	4.6	7.7	-2.8	-1.7	-1.6	-2.8	-2.6	-1.4	-1.9	-1.8	-2.2	-2.1	-1.9	-2.1	-2.2	-2.6	-1.7
Tinnitus: Yes, but not now, but have in the past	3.5	3.8	9.9	-1.6	-2.0	-2.7	-1.5	-0.4	-2.5	-1.6	-1.3	-2.2	-2.1	-2.0	-1.8	-1.9	0.1	-3.1
Age at First Birth	3.2	4.6	7.5	1.9	2.2	2.3	2.3	0.0	2.7	2.0	2.3	2.5	2.3	2.4	2.5	2.4	1.2	1.5
Ulcerative Colitis	3.2	4.6	6.4	1.9	2.0	2.3	2.3	1.8	2.2	2.3	2.0	2.4	2.5	2.2	2.3	2.3	1.6	1.9
Mean time to correctly identify matches	3.0	5.8	9.9	2.5	3.0	2.7	1.9	0.9	3.1	2.2	2.0	2.6	2.6	2.7	2.7	2.6	0.7	2.3
Medication for cholesterol	3.0	4.6	6.8	2.6	1.8	1.8	2.5	2.6	1.9	2.6	1.9	1.9	1.8	2.0	2.2	2.2	2.2	1.9
Ever had stillbirth, spontaneous miscarriage or termination	2.7	2.8	4.2	-2.1	-1.7	-1.8	-1.7	-0.6	-1.7	-1.5	-1.3	-1.8	-2.0	-1.8	-2.0	-2.0	-1.6	-1.1
Worrier / anxious feelings	2.6	4.8	8.0	2.5	1.8	2.0	2.1	0.4	2.6	2.8	1.8	2.4	2.7	2.5	2.6	2.6	1.6	1.3
Supplements: Calcium	2.5	2.8	4.2	1.7	1.2	1.8	1.7	0.7	2.0	1.9	1.5	1.9	1.9	1.9	2.0	1.9	0.8	0.9
Medication: Lansoprazole	2.4	2.8	5.1	-1.6	-1.6	-1.6	-2.1	-0.4	-1.4	-1.5	-1.8	-1.9	-1.7	-1.7	-1.9	-2.0	-2.3	0.2
Birth weight	2.4	5.2	7.3	2.3	2.2	2.3	2.2	1.1	2.5	2.7	2.6	2.2	2.4	2.5	2.5	2.4	2.1	1.7
Alcohol usually taken with meals	2.3	3.6	8.2	2.0	1.8	1.8	1.6	-0.2	2.9	1.8	1.9	2.2	2.2	2.4	2.2	2.1	1.0	1.1
Birth weight of first child	2.3	4.2	10.0	2.3	1.5	1.3	1.9	2.4	1.6	2.5	2.5	1.9	1.8	2.0	2.1	2.0	3.2	-0.1
Prostate Cancer	2.2	3.1	4.9	1.7	1.8	1.7	1.7	1.8	1.7	1.8	2.2	1.6	1.4	1.9	1.6	1.6	1.5	2.0
Blood White Count	2.2	16.5	31.0	-3.9	-3.8	-4.9	-5.6	-2.3	-4.0	-4.0	-3.7	-4.3	-4.0	-4.2	-4.4	-4.5	-2.8	-3.7
Loud music exposure frequency	2.2	2.4	4.0	2.0	1.9	1.2	1.4	0.9	1.5	1.4	1.4	1.5	1.7	1.6	1.7	1.6	1.8	1.1
Hearing aid user	2.2	2.5	4.3	1.4	1.8	1.9	1.5	0.3	1.8	1.7	1.0	1.8	2.1	1.7	1.6	1.6	0.2	2.0
Past tobacco smoking	2.1	3.9	6.5	2.2	2.3	2.1	1.9	1.2	2.3	1.6	1.8	2.0	2.1	2.1	1.9	1.9	1.0	2.5
Hair/balding pattern: Pattern 3	2.1	3.1	4.8	1.4	2.1	2.2	1.9	-0.4	1.9	2.0	1.4	1.9	2.0	1.8	1.9	1.9	1.0	1.9
Number of full sisters	2.1	2.5	4.0	-1.4	-1.4	-1.7	-1.8	-1.4	-1.6	-2.0	-1.4	-1.7	-1.6	-1.5	-1.7	-1.6	-1.2	-1.6
Blood Platelet Count	2.0	22.7	35.5	-4.6	-4.5	-5.4	-5.5	0.1	-5.8	-4.2	-4.2	-5.7	-6.0	-5.3	-5.1	-5.2	-2.6	-3.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.4	3.5	-1.4	-1.9	-1.7	-0.8	-1.2	-1.8	-1.4	-1.8	-1.6	-1.6	-1.8	-1.5	-1.5	-1.0	-1.5
Reaction Time	1.9	3.7	6.9	2.0	2.2	2.2	1.7	0.7	2.6	1.7	1.4	2.1	2.0	2.2	2.0	2.0	0.5	2.2
Noisy workplace	1.9	2.4	4.7	-1.4	-1.6	-2.1	-1.4	-0.3	-1.9	-1.4	-1.3	-1.7	-1.6	-1.7	-1.3	-1.5	-0.7	-2.2
Shortness of breath walking on level ground	1.8	2.1	5.1	1.4	2.2	1.3	1.2	1.2	1.6	0.8	1.5	1.6	1.7	1.6	1.6	1.4	1.2	1.1
Relative age voice broke	1.7	2.6	4.3	-1.5	-1.6	-1.4	-1.7	-1.8	-0.9	-1.9	-2.0	-1.5	-1.7	-1.6	-1.6	-1.4	-2.1	-1.1
Smoking status: Previous	1.7	2.6	4.8	-1.8	-2.2	-1.7	-1.3	-1.3	-1.8	-1.2	-1.5	-1.5	-1.7	-1.7	-1.6	-1.5	-0.6	-2.2
Illnesses of father: None of the above (group 1)	1.7	2.2	3.5	-0.9	-1.4	-1.9	-1.3	-0.8	-1.7	-1.5	-1.9	-1.5	-1.7	-1.6	-1.7	-1.6	-0.6	-1.3
Alcohol drinker status: Never	1.7	2.0	3.3	1.3	1.4	1.8	1.3	1.1	0.9	1.7	1.8	1.4	1.4	1.4	1.4	1.4	1.2	1.6
Major Depression (MDD)	1.6	2.0	3.3	-1.5	-1.2	-1.4	-1.5	-1.2	-1.0	-1.5	-1.8	-1.2	-1.4	-1.4	-1.3	-1.3	-1.6	-1.6
Diabetes (self-reported)	1.6	2.4	7.1	-1.4	-2.0	-2.1	-1.3	-0.0	-1.9	-1.6	-1.0	-1.5	-1.4	-1.5	-1.3	-1.5	-0.2	-2.7
Prospective memory result	1.6	1.9	3.6	1.5	1.2	1.6	1.4	1.0	1.3	1.8	1.3	1.4	1.4	1.4	1.2	1.3	0.9	1.9
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	3.9	-1.5	-1.6	-1.4	-1.1	-1.3	-1.4	-1.2	-2.0	-1.3	-1.1	-1.5	-1.4	-1.2	-1.1	-1.6
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	3.4	1.2	1.1	1.4	1.8	1.1	1.8	1.7	1.4	1.3	1.2	1.5	1.3	1.4	1.6	0.8
Guilty feelings	1.6	2.4	3.3	1.8	1.7	1.5	1.5	0.9	1.5	1.7	1.5	1.7	1.4	1.6	1.6	1.7	1.2	1.6
Commuting to job workplace: Cycle	1.6	2.0	3.2	1.8	1.5	1.2	1.4	1.0	1.7	1.7	1.0	1.5	1.5	1.5	1.6	1.6	0.6	0.9
Schizophrenia vs Biploar Disorder	1.5	1.9	3.1	1.3	1.4	1.5	1.8	-0.9	1.7	1.1	1.0	1.5	1.7	1.5	1.6	1.7	0.6	0.6
Alzheimer’s Disease (including proxy)	1.5	2.2	3.7	-1.9	-1.1	-1.4	-1.2	-0.5	-1.9	-1.2	-1.5	-1.7	-1.6	-1.8	-1.4	-1.6	-1.6	-1.2
Diabetes (mother)	1.5	1.9	5.7	1.3	1.3	0.9	1.4	2.4	0.4	1.3	1.8	1.1	1.1	1.1	1.4	1.3	2.0	-0.0
Bilateral oophorectomy (both ovaries removed)	1.5	1.8	5.8	-1.4	-0.2	-0.7	-1.6	-1.6	-0.6	-1.5	-1.5	-1.4	-1.3	-1.1	-1.2	-1.3	-2.4	-0.2
Fluid intelligence score	1.5	3.2	4.8	1.8	1.5	1.9	1.7	0.4	2.2	1.9	1.9	2.0	2.0	2.1	2.2	2.0	1.4	0.9
Basal cell carcinoma (self-reported)	1.5	1.8	2.8	-1.3	-1.6	-1.7	-1.4	0.4	-1.5	-1.3	-0.9	-1.5	-1.4	-1.4	-1.3	-1.4	-0.7	-1.6
Ovarian Cancer	1.4	1.8	3.2	1.2	1.3	1.8	1.1	0.3	1.5	1.8	1.2	1.3	1.4	1.4	1.4	1.5	0.7	1.4
Father’s age at death	1.4	1.9	3.2	1.6	0.8	1.6	1.1	-0.2	1.8	1.8	0.8	1.6	1.6	1.6	1.4	1.6	0.5	1.6
Mouth/teeth dental problems: Dentures	1.4	2.4	5.2	1.8	1.2	0.8	1.4	0.7	1.5	1.7	2.0	1.7	1.6	1.8	1.8	1.6	2.3	0.0
Blood clot in the leg (DVT)	1.4	1.8	2.9	-1.5	-1.1	-1.4	-1.4	-0.4	-1.6	-1.4	-1.0	-1.6	-1.5	-1.5	-1.5	-1.7	-1.3	-0.6
Illnesses of father: Heart disease	1.4	2.0	3.9	1.2	1.4	1.5	1.6	1.3	1.0	0.9	1.6	1.3	1.5	1.3	1.2	1.3	1.5	2.0
Unable to work because of sickness or disability	1.4	1.8	3.8	-1.2	-0.9	-2.0	-1.2	-0.1	-1.5	-1.5	-1.2	-1.5	-1.4	-1.5	-1.1	-1.5	-1.2	-1.6
Blood Eosinophil Count	1.3	10.0	16.8	-3.5	-2.6	-3.6	-3.3	0.4	-4.1	-2.7	-2.7	-4.0	-3.6	-3.7	-3.8	-3.7	-1.4	-2.0
Hair/balding pattern: Pattern 2	1.3	1.6	4.2	-1.4	-1.0	-0.8	-1.6	-1.7	-0.3	-1.9	-1.2	-0.9	-1.1	-0.9	-1.2	-1.2	-2.0	-0.5
Medication: Paracetamol	1.3	2.2	3.4	-1.8	-1.4	-1.6	-1.6	-0.5	-1.5	-1.5	-1.4	-1.8	-1.4	-1.6	-1.7	-1.6	-1.0	-1.3
Illnesses of father: High blood pressure	1.3	1.6	3.2	-1.8	-1.1	-1.0	-1.1	-0.5	-1.3	-1.4	-0.9	-1.3	-1.7	-1.3	-1.4	-1.3	-1.2	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	2.7	-1.5	-1.1	-1.5	-1.3	-0.2	-1.6	-1.3	-1.0	-1.5	-1.5	-1.5	-1.5	-1.6	-1.2	-0.9
Alzheimer’s Disease (in mother)	1.2	1.4	3.9	-1.5	-0.5	-1.2	-0.5	1.1	-2.0	-1.1	-0.9	-1.3	-1.5	-1.5	-1.3	-1.3	-0.2	-0.6
Ever taken oral contraceptive pill	1.2	1.3	2.3	-1.3	-1.0	-1.3	-1.5	-0.0	-0.9	-1.5	-0.5	-1.2	-1.3	-1.1	-1.4	-1.3	-0.2	-1.3
Heart disease (siblings)	1.2	1.5	3.0	0.9	1.7	1.2	1.3	0.4	1.0	1.6	1.2	1.1	1.5	1.2	1.4	1.2	1.0	0.6
HbA1C	1.1	1.2	2.8	-1.1	-1.3	-1.0	-1.0	-1.7	-0.8	-1.4	-1.4	-1.2	-1.0	-1.2	-1.0	-1.1	0.2	-0.5
Cardiovascular Disease	1.1	3.8	6.2	-2.4	-1.8	-1.7	-1.9	-2.0	-1.8	-2.5	-1.9	-1.7	-1.5	-1.9	-2.0	-2.1	-1.9	-1.7
Neuroticism	1.1	2.6	3.6	1.8	1.5	1.5	1.5	1.3	1.6	1.9	1.8	1.7	1.6	1.7	1.9	1.8	1.4	1.2
Hayfever, allergic rhinitis or eczema	1.1	2.3	3.9	1.6	1.5	1.7	1.5	1.3	1.6	1.6	1.1	2.0	1.2	1.5	1.4	1.7	1.2	1.7
Time employed in main current job	1.1	1.2	4.1	-1.0	-1.1	-0.6	-1.4	-1.5	-0.7	-1.1	-1.3	-1.0	-0.4	-1.0	-0.8	-1.0	-2.0	0.2
Overall health rating	1.1	2.3	5.4	-1.5	-1.2	-2.0	-1.4	0.8	-1.8	-2.3	-0.9	-1.5	-1.4	-1.4	-1.4	-1.6	-0.6	-1.8
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	2.9	-1.2	-1.4	-1.4	-1.3	-0.8	-1.6	-0.8	-1.7	-1.3	-1.5	-1.5	-1.2	-1.2	-1.4	-1.5
Coronary Artery Disease (CAD)	1.0	1.2	1.8	-1.2	-0.6	-1.3	-1.3	-0.8	-1.2	-0.9	-0.8	-1.2	-1.0	-0.8	-1.4	-1.2	-0.7	-1.3
Qualifications: CSEs or equivalent	1.0	1.3	2.5	-1.2	-0.6	-1.2	-0.8	-0.2	-1.4	-1.6	-1.0	-1.3	-1.4	-1.3	-1.4	-1.4	-0.6	-0.2
Had major operations	1.0	1.2	2.1	-0.8	-0.8	-1.3	-1.4	-0.7	-1.2	-1.1	-1.1	-1.1	-1.1	-1.3	-1.4	-1.2	-0.6	-0.8
Neuroticism (Nagel 2018)	0.9	2.0	3.2	1.7	1.3	1.5	1.2	0.4	1.6	1.8	1.2	1.6	1.5	1.6	1.6	1.8	1.0	0.8
Crohns Disease (2012)	0.9	1.5	4.4	1.6	0.9	0.2	0.9	2.1	0.7	1.7	0.6	1.4	1.2	0.9	1.5	1.3	1.6	-0.6
Sensitivity / hurt feelings	0.9	1.6	2.7	1.4	1.6	1.3	0.9	-0.2	1.6	1.1	0.9	1.3	1.6	1.4	1.4	1.3	0.1	1.4
Vitamin and mineral supplements	0.9	1.2	2.3	-1.2	-0.9	-1.2	-1.1	-0.3	-1.5	-1.3	-0.7	-1.2	-1.2	-1.2	-1.4	-1.4	-0.5	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	3.8	-1.0	-1.2	-1.9	-1.8	0.3	-1.6	-1.8	-1.1	-1.5	-1.5	-1.4	-1.4	-1.6	-0.5	-1.6
Depression (self-reported)	0.9	1.0	5.8	0.9	1.1	0.1	0.8	2.4	-0.2	0.8	0.8	0.6	0.2	0.4	0.5	0.6	2.0	-0.3
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.1	-1.1	-0.8	-0.7	-1.1	-0.6	-1.2	-1.5	-0.8	-1.1	-1.2	-1.1	-1.2	-1.1	-1.1	0.3
Commuting to job workplace: Walk	0.9	1.0	2.0	1.4	0.3	0.9	1.4	1.1	0.8	1.2	0.8	1.0	0.9	1.0	1.0	1.1	1.1	0.7
Irritable Bowel Disease (IBD)	0.8	2.0	3.7	1.9	1.1	1.0	1.3	1.9	1.0	1.7	1.1	1.9	1.3	1.2	1.6	1.5	1.2	0.7
Ulcerative Colitis (UC)	0.8	1.5	2.5	1.5	0.9	1.5	1.2	0.7	1.3	1.2	0.9	1.6	1.3	1.1	1.1	1.3	0.6	1.6
Medication: Co-codamol	0.8	1.0	1.8	-1.1	-0.5	-1.1	-1.1	-1.0	-1.0	-1.1	-0.5	-1.1	-1.1	-1.0	-1.3	-1.2	-0.3	-0.9
Happiness	0.8	0.9	2.2	0.8	1.2	0.9	0.2	-0.3	1.5	0.7	1.3	1.1	1.0	1.2	1.0	0.9	0.6	0.9
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.2	-0.7	-0.7	-1.3	-1.0	0.1	-1.1	-1.3	-0.8	-1.2	-1.2	-1.1	-1.5	-1.4	-0.0	0.0
Age at last live birth	0.8	1.2	2.1	1.0	0.9	1.4	1.2	-0.7	1.4	1.3	0.9	1.2	1.1	1.2	1.1	1.3	0.4	0.8
Medication: Aspirin	0.8	1.1	4.4	0.6	1.5	1.0	0.6	2.1	0.5	0.5	1.3	0.7	0.7	0.7	0.4	0.6	1.7	1.1
Illnesses of siblings: Diabetes	0.8	1.0	3.3	-1.0	-0.5	-0.5	-1.7	-1.5	-0.4	-1.2	-0.7	-0.8	-0.7	-0.7	-1.0	-1.0	-1.8	0.1
Medication: Aspirin	0.8	1.1	3.7	0.6	1.6	1.0	0.4	1.9	0.6	0.5	1.4	0.8	0.8	0.8	0.5	0.6	1.5	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	2.9	1.6	1.7	1.4	1.4	0.6	1.3	1.4	0.9	1.2	1.3	1.2	1.2	1.4	1.2	1.5
Number of operations (self-reported)	0.8	1.2	2.7	-1.1	-0.8	-1.4	-1.6	-0.4	-1.1	-0.8	-0.6	-1.2	-1.1	-1.0	-0.9	-1.2	-0.9	-1.2
Average weekly beer plus cider intake	0.8	1.1	2.9	-0.8	-1.5	-0.9	-0.9	0.2	-1.7	-0.5	-1.1	-1.3	-1.1	-1.3	-1.0	-1.0	-0.9	-0.6
Risk taking	0.8	1.1	2.3	-0.7	-1.3	-1.2	-1.0	-0.0	-0.9	-1.3	-1.0	-1.1	-1.5	-1.0	-1.3	-1.4	-0.8	-0.3
Cholesterol lowering medication	0.8	1.2	2.7	-1.2	-1.1	-1.1	-1.1	-0.7	-1.6	-1.1	-0.8	-1.1	-1.0	-1.3	-1.1	-1.2	-0.8	-0.8
Worry (Nagel 2018)	0.7	1.5	2.5	1.6	1.1	1.1	1.3	0.2	1.4	1.4	0.9	1.3	1.4	1.3	1.4	1.5	0.7	0.6
Crohns Disease (2017)	0.7	1.6	4.9	1.8	0.9	0.1	0.9	2.2	0.5	1.7	0.9	1.5	1.0	0.9	1.5	1.2	1.5	-0.6
Smoking Status	0.7	1.8	3.6	-1.9	-1.2	-1.4	-1.3	-0.3	-1.4	-1.5	-1.0	-1.4	-1.4	-1.3	-1.4	-1.4	-0.7	-1.6
Average weekly spirits intake	0.7	0.9	1.7	-1.3	-1.2	-0.7	-0.4	-1.3	-0.9	-1.3	-0.7	-0.9	-0.9	-0.9	-1.3	-1.1	-0.4	-0.4
Neuroticism score	0.7	1.4	2.5	1.3	1.1	0.9	1.2	0.1	1.3	1.3	1.2	1.4	1.3	1.3	1.6	1.5	0.8	0.4
Medication: Cholesterol lowering	0.7	1.1	1.8	1.2	0.8	1.0	0.8	1.0	1.4	0.7	1.2	1.1	1.2	1.2	0.9	1.0	1.2	0.9
Length of working week for main job	0.7	0.7	1.1	-0.9	-0.6	-0.8	-1.0	-0.3	-0.8	-1.0	-0.9	-1.0	-1.0	-0.9	-0.9	-0.9	-1.0	0.3
Medication for pain relief, constipation, heartburn	0.7	1.2	2.3	1.3	0.5	1.1	0.8	-0.6	1.4	1.5	1.0	1.4	1.1	1.4	1.4	1.3	-0.1	0.7
Diabetes diagnosed by doctor	0.7	1.2	5.2	-0.7	-1.5	-1.6	-0.9	0.5	-1.3	-0.9	-0.6	-0.9	-0.9	-1.0	-0.7	-0.9	0.1	-2.3
Osteoporosis (self-reported)	0.7	0.8	1.9	1.4	0.3	0.6	0.9	-0.0	1.1	1.2	0.4	1.1	1.3	0.9	1.1	1.1	0.4	-0.1
Financial situation satisfaction	0.7	0.9	2.4	-0.8	-0.7	-1.1	-1.1	-0.9	-0.5	-1.5	-0.7	-0.7	-1.0	-0.8	-0.8	-1.0	-0.8	-1.1
Intelligence (Savage-Jansen 2018)	0.6	1.8	4.3	1.3	1.1	1.3	1.5	0.5	2.1	1.4	1.0	1.5	1.5	1.6	1.8	1.6	0.3	0.2
Rheumatoid Arthritis	0.6	0.8	2.5	-0.9	-1.3	-0.5	-1.0	-1.6	-0.3	-0.9	-1.1	-0.7	-0.5	-0.7	-0.6	-0.6	-1.0	-1.0
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.7	1.1	0.5	1.0	0.9	0.1	1.0	1.0	0.7	0.8	0.7	0.8	0.8	0.8	0.2	1.3
Systolic Blood Pressure	0.6	3.1	7.3	-2.1	-1.5	-1.0	-1.5	-2.7	-1.6	-2.6	-1.4	-1.5	-1.2	-1.7	-1.7	-1.7	-2.0	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.2	2.4	-0.8	-0.7	-1.5	-1.4	0.4	-1.4	-1.5	-0.7	-1.2	-1.1	-1.1	-1.1	-1.2	-0.1	-1.0
Serious illness, injury or assault to yourself	0.6	0.7	1.1	-0.8	-0.8	-0.6	-1.1	-0.4	-1.1	-1.0	-1.0	-0.8	-0.6	-0.9	-0.7	-0.7	-1.0	-0.4
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.3	0.7	1.2	0.4	0.4	0.4	1.0	0.7	0.6	1.0	1.0	0.8	1.1	1.0	0.8	-0.7
Asthma	0.6	1.2	2.1	1.2	0.8	1.0	1.1	0.7	1.5	1.4	0.6	1.4	1.3	1.1	1.2	1.2	0.6	0.7
Illnesses of mother	0.6	0.8	2.1	-0.2	-1.0	-1.1	-1.0	-1.2	0.1	-0.6	-1.5	-0.5	-0.7	-0.6	-0.6	-0.7	-1.2	-1.1
Health satisfaction	0.6	0.8	2.4	-0.9	-0.6	-0.9	-0.9	-0.8	-0.1	-1.6	-1.0	-0.6	-0.6	-0.6	-0.7	-0.8	-1.3	-0.8
Average weekly red wine intake	0.6	0.9	4.1	-0.9	-0.8	-0.2	-1.2	-2.0	0.2	-1.0	-0.9	-0.6	-0.7	-0.4	-0.7	-0.7	-1.7	-0.1
Osteoarthritis (self-reported)	0.6	0.7	1.7	-0.4	-0.5	-1.2	-0.7	1.2	-1.3	-0.4	-0.5	-1.1	-0.8	-0.8	-0.8	-0.8	0.5	-1.1
Wears glasses or contact lenses	0.6	0.7	2.0	0.7	0.9	1.4	0.8	0.7	0.7	0.9	0.5	0.9	0.8	0.8	0.8	1.0	0.5	1.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.5	-0.7	-0.6	-0.8	-1.0	-1.2	-0.1	-0.9	-1.3	-0.7	-0.8	-0.6	-0.5	-0.6	-1.6	-0.9
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.3	0.8	1.0	1.1	1.2	-0.0	1.5	1.0	1.1	1.0	1.2	1.2	1.3	1.2	0.7	0.1
Bipolar Disorder (2011)	0.5	0.4	2.7	-0.0	-0.3	0.0	-0.7	1.6	-0.8	0.1	0.1	-0.4	-0.4	-0.4	-0.7	-0.5	0.1	1.2
Body Mass Index (BMI) (2010)	0.5	0.7	1.4	-1.1	-0.5	-0.7	-0.5	-0.5	-1.2	-0.7	-0.5	-1.2	-0.9	-1.0	-1.2	-1.0	-0.1	-0.5
Schizophrenia (2014)	0.5	1.2	2.1	1.1	0.9	1.3	1.0	-0.4	1.5	1.0	0.7	1.3	1.3	1.2	0.9	1.2	0.5	1.2
Height	0.5	9.0	17.2	3.8	3.4	2.7	4.2	1.6	2.5	2.7	2.4	2.9	3.0	2.8	3.0	3.2	3.6	2.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.4	-0.6	-0.8	-1.1	-1.0	0.4	-0.2	-1.0	-0.9	-0.7	-0.8	-0.7	-0.7	-0.8	-1.2	-1.1
Pack years adult smoking proportion	0.5	0.7	2.8	-0.8	-0.2	-0.9	-0.7	0.8	-1.7	-0.9	-0.4	-1.0	-1.1	-1.0	-0.8	-0.9	-0.2	-0.4
Impedance of leg (right)	0.5	2.3	5.0	-1.0	-1.9	-0.7	-1.3	-1.4	-1.2	-1.2	-2.2	-1.5	-1.9	-1.6	-1.8	-1.4	-1.9	0.7
Fed-up feelings	0.5	0.9	1.7	0.8	1.2	1.1	1.0	0.5	0.7	1.3	0.9	1.0	0.9	0.9	1.1	1.1	0.6	0.8
High blood pressure	0.5	1.3	2.3	-1.5	-0.8	-0.7	-1.3	-0.8	-1.5	-1.4	-0.8	-1.1	-1.0	-1.2	-1.2	-1.2	-1.2	-0.7
Supplements: Glucosamine	0.5	0.7	4.1	-0.5	-0.6	-0.4	-0.9	-2.0	0.3	-0.8	-0.9	-0.6	-0.2	-0.3	-0.4	-0.5	-1.5	-0.4
Allergy	0.5	1.1	2.3	-1.1	-0.8	-1.1	-1.1	-1.5	-1.1	-1.1	-0.7	-1.4	-0.7	-0.9	-1.0	-1.0	-0.6	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	3.9	1.6	1.6	1.2	1.5	-0.1	1.6	1.1	0.7	1.0	1.2	1.2	1.0	1.2	0.8	2.0
Impedance of arm (left)	0.5	2.2	6.2	1.4	1.0	2.1	1.2	0.7	1.6	1.8	1.1	1.3	1.2	1.5	1.3	1.5	0.5	2.5
Forced vital capacity (FVC), Best measure	0.5	1.7	3.1	1.8	1.5	1.1	1.5	-0.3	1.7	1.3	0.4	1.1	1.4	1.2	1.2	1.4	0.5	1.8
Leg fat percentage (right)	0.5	1.7	4.0	-1.1	-1.0	-1.6	-1.2	1.4	-2.0	-1.9	-0.4	-1.4	-1.2	-1.2	-1.4	-1.6	-0.0	-0.7
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.5	0.8	0.6	0.4	0.5	1.2	0.6	0.4	0.8	1.0	0.8	0.8	0.9	0.7	0.9	0.6
Medication: Allopurinol	0.5	0.7	1.3	1.0	0.5	0.8	0.7	0.2	1.0	0.5	0.8	0.9	1.1	0.9	0.9	0.8	0.6	1.0
Medication: Omeprazole	0.5	0.6	1.5	0.4	1.1	0.6	1.1	0.8	0.5	0.2	1.0	0.7	0.5	0.8	0.6	0.6	1.2	0.6
Comparative height size at age 10	0.5	2.6	5.8	1.9	1.9	1.1	2.4	0.9	1.2	1.1	1.7	1.6	1.7	1.6	1.9	1.8	1.9	0.4
Average weekly champagne plus white wine intake	0.5	0.7	1.5	1.0	0.4	0.7	1.2	0.9	0.6	0.9	1.0	0.8	0.6	0.9	0.8	0.8	1.2	0.7
Age started oral contraceptive pill	0.5	0.7	1.8	0.9	0.6	0.8	0.7	1.2	0.1	1.4	0.9	0.5	0.7	0.6	0.8	0.7	0.6	1.1
Alcohol drinker status: Previous	0.5	0.5	1.2	-0.9	-0.7	-0.4	-0.5	-0.0	-1.0	-0.9	-0.4	-0.9	-1.1	-0.8	-0.9	-0.8	-0.1	-0.4
Bipolar Disorder (2018)	0.4	0.7	1.3	-0.7	-1.1	-0.9	-1.2	-0.1	-1.0	-0.7	-0.9	-0.8	-0.9	-0.9	-0.9	-0.9	-0.5	-0.5
Schizophrenia (2018)	0.4	0.7	1.5	0.9	1.0	0.9	0.8	0.7	1.0	0.9	0.7	1.0	0.8	0.9	0.7	0.8	0.5	1.2
BMI	0.4	2.1	4.8	-1.7	-1.0	-1.9	-1.1	1.0	-2.2	-2.0	-0.3	-1.6	-1.0	-1.3	-1.5	-1.9	0.2	-1.4
Respiratory disease	0.4	1.0	1.7	1.2	0.6	0.6	0.8	1.3	1.1	1.2	0.7	1.3	1.1	1.0	1.2	1.1	0.8	0.2
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.2	1.0	0.8	0.1	0.8	0.9	0.4	0.8	0.8	0.8	0.6	0.6	0.8	0.7	1.1	-0.2
Angina	0.4	0.5	1.3	0.3	1.0	0.5	0.2	0.5	0.8	0.7	1.2	0.6	0.8	0.9	1.0	0.7	0.6	0.1
Multivitamins +/- minerals	0.4	0.5	0.9	1.0	-0.0	0.3	0.7	0.9	0.9	0.8	0.4	0.7	0.7	0.7	0.7	0.7	0.8	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.3	0.8	1.2	0.6	0.5	0.7	0.6	0.5	0.9	0.9	0.6	0.8	0.9	0.7	-0.1	0.7
Had other major operations	0.4	0.5	1.6	-0.5	-0.2	-0.9	-0.5	1.3	-0.9	-0.6	0.3	-0.4	-0.6	-0.4	-0.3	-0.5	0.7	-1.2
Qualifications: None of the above	0.4	0.9	3.8	-1.1	-0.5	-0.8	-0.7	0.4	-1.9	-1.0	-0.2	-1.3	-1.0	-1.1	-1.1	-1.2	0.0	-0.3
Mouth/teeth dental problems	0.4	0.6	2.4	-0.7	0.2	0.5	-0.1	-1.4	0.3	-0.7	-0.5	-0.4	-0.0	-0.2	-0.5	-0.4	-1.5	1.4
Pain all over the body in last month	0.4	0.4	4.8	-0.1	0.0	-0.5	-0.4	2.2	-0.1	-0.0	0.4	-0.3	-0.3	-0.0	-0.2	-0.3	0.4	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.5	-0.6	-0.6	-1.5	-0.8	-0.3	-0.4	-1.2	-0.6	-0.7	-0.7	-0.6	-0.6	-0.9	-0.3	-1.6
Pulse rate	0.4	0.6	1.2	0.7	0.7	0.4	0.7	0.3	0.9	0.9	1.0	1.1	0.5	0.9	1.0	0.8	0.8	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.8	-0.0	-0.8	-0.5	-0.8	-0.5	-0.7	-0.8	-0.7	-0.5	-0.7	-0.6	-0.9	-0.7	-0.4	0.8
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.6	-0.1	-0.6	-0.7	-0.3	1.6	-1.0	0.3	-0.2	-0.2	-0.5	-0.5	-0.2	-0.2	0.8	-1.3
Pulse rate, automated reading	0.4	1.4	2.9	1.1	0.9	1.1	0.6	-0.6	1.7	1.0	1.3	1.5	1.4	1.5	1.6	1.4	0.1	0.4
Suffer from ‘nerves’	0.4	0.6	1.0	0.7	0.9	0.7	0.8	-0.7	0.9	0.6	0.5	0.9	1.0	0.8	1.0	1.0	0.2	-0.1
Knee pain experienced in last month	0.4	0.7	1.9	-0.8	-0.4	-1.1	-0.9	-0.5	-0.9	-1.1	-0.6	-0.8	-0.7	-0.8	-0.8	-0.9	-0.3	-1.4
Hypertension (Self-reported)	0.4	1.1	2.0	-1.4	-0.7	-0.5	-1.3	-0.9	-1.4	-1.4	-0.8	-0.9	-0.9	-1.1	-1.2	-1.2	-1.0	-0.4
Ever had bowel cancer screening	0.4	0.5	3.5	-0.8	-0.4	0.0	-0.7	-1.9	0.3	-0.4	-0.2	-0.4	0.0	-0.0	-0.4	-0.4	-1.1	0.3
Qualifications: nursing, teaching	0.4	0.6	1.9	0.8	0.9	0.8	0.3	0.3	1.4	0.5	0.2	0.8	0.9	0.9	0.6	0.7	-0.4	1.3
Mineral and other dietary supplements	0.4	0.6	2.7	0.1	0.6	0.6	0.6	1.6	-0.5	0.4	0.9	0.2	0.2	0.1	-0.1	0.1	1.3	1.2
Asthma (self-reported)	0.4	0.9	1.5	1.0	0.7	0.7	1.0	0.8	1.2	1.2	0.5	1.2	1.1	0.9	1.1	1.0	0.5	0.4
Miserableness	0.4	0.6	2.0	1.2	0.5	0.2	0.6	0.2	0.6	1.0	0.7	0.8	0.7	0.7	0.9	1.0	1.4	-0.5
Mother’s age at death	0.4	0.5	1.2	0.5	0.7	0.9	1.1	0.0	0.8	0.7	0.6	0.8	0.8	0.9	0.9	1.0	0.3	0.4
Commuting to job workplace: Public transport	0.4	0.5	2.0	0.9	0.6	0.9	-0.0	-0.5	1.0	0.1	0.3	0.5	0.7	0.8	0.5	0.6	-0.6	1.4
High cholesterol (Self-reported)	0.4	0.8	1.7	-1.2	-0.7	-0.4	-1.1	-1.1	-0.6	-1.2	-1.0	-0.7	-0.5	-0.8	-0.8	-0.8	-1.3	-0.5
Irritability	0.4	0.6	1.4	0.8	0.2	0.8	0.6	-0.5	1.2	0.9	0.5	0.9	0.7	0.9	0.9	0.8	0.1	1.0
HDL Cholesterol	0.3	0.6	1.2	0.6	0.5	0.9	0.8	0.5	0.3	1.1	1.0	0.8	0.8	0.7	0.9	0.7	1.0	0.3
Triglycerides	0.3	0.5	2.1	0.1	-0.0	0.6	-0.2	-1.4	1.3	-0.1	0.0	0.4	0.2	0.4	0.2	0.3	-1.4	0.9
Waist Hip Ratio (WHR)	0.3	1.3	2.2	1.1	1.3	1.1	1.0	1.2	0.3	1.5	1.4	0.9	1.1	1.0	1.2	1.1	1.1	1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.4	-0.5	-1.1	-1.0	-0.4	0.5	-1.0	-0.4	-0.2	-0.6	-0.6	-0.6	-0.5	-0.7	0.3	-1.2
Chronotype (morning person)	0.3	0.6	1.8	-0.9	-0.7	-1.3	-0.5	-0.5	-0.4	-0.9	-0.6	-0.7	-0.6	-0.7	-0.8	-1.0	-0.4	-1.3
Relative age of first facial hair	0.3	0.7	3.3	-0.5	-0.8	-0.5	-0.7	-1.1	0.2	-0.9	-1.2	-0.7	-0.4	-0.6	-0.5	-0.6	-1.8	0.6
Average weekly fortified wine intake	0.3	0.3	1.0	0.5	0.3	0.9	0.3	-0.8	0.8	0.1	-0.1	0.5	0.5	0.5	0.3	0.5	-0.7	1.0
Taking other prescription medications	0.3	0.5	1.0	0.6	0.9	0.4	0.4	1.0	0.8	0.2	0.5	0.8	1.0	0.7	0.7	0.7	0.7	-0.1
Body mass index (BMI)	0.3	1.3	3.2	-1.1	-0.3	-1.5	-0.8	1.4	-1.8	-1.7	0.3	-1.1	-0.7	-0.9	-1.0	-1.3	0.5	-1.3
Impedance of leg (left)	0.3	1.3	2.7	-0.8	-1.4	-0.3	-1.1	-0.8	-0.9	-0.8	-1.6	-1.1	-1.6	-1.2	-1.3	-1.0	-1.6	1.0
Had menopause	0.3	0.3	1.2	-0.8	-0.3	-0.0	-0.5	-1.0	-0.6	-0.0	-0.4	-0.4	-0.3	-0.5	-0.1	-0.2	-1.1	-0.6
Forced vital capacity (FVC)	0.3	1.1	2.7	1.6	1.0	0.5	1.2	-0.5	1.5	1.2	0.1	0.9	1.1	0.9	1.0	1.1	0.6	0.9
Financial difficulties in last 2 years	0.3	0.5	1.1	-0.5	0.1	-1.0	-0.6	0.7	-1.1	-0.7	0.0	-0.7	-0.7	-0.7	-0.7	-0.9	0.3	-0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.0	0.8	0.6	0.2	0.7	1.0	0.3	0.8	0.2	0.8	0.1	0.4	0.7	0.7	0.8	-0.6
Impedance of arm (right)	0.3	1.5	4.8	1.3	0.7	1.8	1.0	0.4	1.5	1.5	0.8	1.1	1.1	1.2	1.0	1.3	0.4	2.2
Number of live births	0.3	0.4	1.9	-0.6	-0.0	-0.9	-0.2	0.6	-0.9	-0.4	0.1	-0.6	-0.7	-0.5	-0.4	-0.6	0.4	-1.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	2.0	0.3	0.6	0.4	1.3	0.7	-0.3	0.6	0.3	0.2	0.4	0.1	0.3	0.4	1.4	0.1
Standing height	0.3	3.3	7.0	2.4	1.4	1.5	2.6	-0.0	2.1	1.4	1.4	2.0	1.9	2.0	1.9	2.0	1.8	1.1
Breastfed as a baby	0.3	0.4	0.8	-0.5	-0.5	-0.5	-0.8	0.3	-0.9	-0.7	-0.7	-0.6	-0.7	-0.7	-0.7	-0.6	-0.2	-0.5
Hair/balding pattern: Pattern 4	0.3	0.6	1.8	1.3	0.3	0.3	0.9	0.9	0.6	0.9	0.6	0.6	0.8	0.7	0.7	0.8	1.3	0.1
Peak expiratory flow (PEF)	0.3	0.8	1.8	-0.7	-0.4	-1.0	-0.6	-0.7	-0.5	-1.2	-0.8	-1.2	-1.0	-0.9	-1.3	-1.2	-0.5	0.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.2	-0.8	-0.6	-0.7	-0.2	-1.1	-0.7	-0.2	-0.7	-0.8	-0.7	-0.7	-0.4	-0.4	-0.6	-1.0
Pulse wave peak to peak time	0.3	0.3	1.0	0.8	0.8	0.3	0.6	0.2	0.4	0.3	0.5	0.5	0.8	0.6	0.5	0.6	1.0	0.1
Qualifications: College or University degree	0.3	0.9	5.1	0.7	0.4	0.8	0.4	-0.8	2.3	0.7	0.5	1.0	0.8	1.1	0.7	0.8	-0.4	0.8
Medication: Blood pressure	0.3	0.5	1.0	-0.6	-0.7	-0.6	-1.0	-0.1	-0.7	-0.9	-0.9	-0.7	-0.6	-0.8	-0.9	-0.9	-0.7	-0.0
Angina (self-reported)	0.3	0.4	1.0	0.2	0.9	0.4	0.1	0.3	0.8	0.5	1.0	0.5	0.7	0.8	0.9	0.6	0.4	0.1
Medication: Ibuprofen	0.3	0.4	1.5	0.4	0.7	0.7	1.2	0.4	0.1	0.7	0.5	0.4	0.6	0.4	0.5	0.6	1.1	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.0	-0.7	-0.6	-0.7	-0.4	-1.0	-0.3	-0.8	-0.7	-0.2	-0.6	-0.4	-0.3	-0.4	-0.8	-1.0
Alcohol intake frequency.	0.3	0.8	1.9	0.9	1.4	0.7	0.4	1.3	0.5	0.2	1.2	0.6	0.9	0.8	0.7	0.6	0.9	1.1
Chest pain or discomfort	0.3	0.4	0.8	0.5	0.4	0.0	0.5	0.4	0.7	0.9	0.6	0.7	0.7	0.8	0.9	0.6	0.5	-0.6
Leg pain on walking	0.3	0.4	1.3	-0.7	-0.1	-0.7	-0.6	-0.1	-0.5	-1.1	-0.6	-0.6	-0.3	-0.6	-0.7	-0.6	-0.3	-0.7
Supplements: Vitamin C	0.3	0.4	0.9	0.5	0.9	0.7	0.6	-0.1	0.9	0.5	0.3	0.5	0.6	0.7	1.0	0.7	-0.4	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.0	-0.4	-0.4	-0.6	-0.6	-0.2	-0.2	-0.6	-1.0	-0.5	-0.7	-0.5	-0.6	-0.6	-0.6	-0.2
Leg fat-free mass (right)	0.3	1.6	4.3	1.1	1.5	0.3	1.6	1.4	0.7	0.5	1.8	1.1	1.4	1.2	1.2	1.0	2.1	-0.5
Friendships satisfaction	0.3	0.3	3.7	0.1	-0.6	0.2	-0.6	-1.9	0.6	0.0	-0.3	0.2	0.1	0.2	0.1	0.2	-0.3	0.0
Leg predicted mass (right)	0.3	1.6	4.3	1.1	1.5	0.3	1.6	1.4	0.7	0.5	1.8	1.1	1.3	1.2	1.2	1.0	2.1	-0.6
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.3	0.6	0.2	0.5	0.5	-0.2	1.1	0.3	0.8	0.8	0.8	0.8	0.9	0.7	-0.2	-0.0
Leg fat percentage (left)	0.3	1.2	3.1	-0.9	-0.6	-1.2	-0.9	1.8	-1.8	-1.6	0.1	-1.1	-1.0	-0.9	-1.0	-1.3	0.3	-0.5
Myopia	0.3	0.4	2.1	-0.8	-0.8	0.3	-0.2	-1.5	0.2	-0.6	-0.6	-0.1	-0.3	-0.3	-0.5	-0.2	-1.1	-0.1
Pain experienced in last month	0.3	0.5	1.4	-0.2	-1.1	-0.5	-0.7	-0.9	-0.5	-0.4	-1.2	-0.4	-0.5	-0.7	-0.4	-0.5	-1.2	-0.4
Blood Red Count	0.2	1.5	12.0	0.8	0.9	0.7	0.1	2.4	0.5	-0.2	1.3	0.3	-0.1	0.6	-0.4	-0.2	0.3	3.5
Allergy or Eczema	0.2	0.5	1.5	0.9	1.0	0.8	0.3	0.6	0.7	0.3	0.2	1.1	0.3	0.6	0.6	0.8	0.0	1.2
Lung FVC	0.2	1.0	3.6	1.3	1.1	0.8	1.0	0.4	1.1	1.5	-0.0	0.5	1.1	0.6	0.7	0.9	0.1	1.9
Ever had hysterectomy (womb removed)	0.2	0.2	1.4	-0.1	0.7	0.3	0.1	-1.2	0.0	-0.0	0.2	-0.3	-0.2	0.1	-0.1	-0.2	-0.6	0.6
Supplements: Zinc	0.2	0.2	0.9	0.5	0.0	-0.3	0.5	-0.1	0.6	0.0	0.0	0.4	0.3	0.3	0.4	0.3	0.4	-1.0
Diabetes (father)	0.2	0.3	0.9	-0.5	-0.5	-0.4	-0.6	-0.4	0.1	-0.9	-0.1	-0.5	-0.6	-0.3	-0.7	-0.6	-0.7	0.4
Leg fat-free mass (left)	0.2	1.1	4.0	1.0	1.2	0.1	1.5	1.2	0.4	0.2	1.5	0.8	1.1	0.9	0.9	0.7	2.0	-0.7
Trunk fat percentage	0.2	0.7	6.1	-0.0	0.4	-0.1	0.2	2.5	-0.9	-0.6	1.1	-0.2	0.1	0.1	-0.1	-0.3	1.1	0.5
Hand grip strength (right)	0.2	0.5	0.9	-0.3	-0.8	-0.8	-0.6	-0.9	-0.7	-0.5	-1.0	-0.7	-0.8	-0.8	-0.7	-0.7	-0.8	-0.3
Townsend deprivation index at recruitment	0.2	0.3	1.0	-0.4	-0.3	0.2	-0.5	-0.4	-0.6	-0.4	-0.1	-0.4	-0.4	-0.5	-0.6	-0.5	-0.6	1.0
Stomach or abdominal pain in last month	0.2	0.2	0.4	-0.6	-0.5	-0.6	-0.3	0.2	-0.6	-0.6	-0.1	-0.6	-0.6	-0.5	-0.5	-0.7	-0.2	-0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.6	0.1	0.2	0.2	0.3	1.3	0.4	0.5	0.3	0.1	0.2	0.3	0.2	0.1	-0.0	0.6
Medication: Levothyroxine sodium	0.2	0.3	1.2	-1.0	-0.7	-0.2	-0.4	-0.5	-0.6	-1.1	0.1	-0.3	-0.6	-0.4	-0.5	-0.5	-0.3	-0.0
Sitting height	0.2	1.4	5.8	1.2	0.5	0.2	2.1	1.1	0.6	1.0	1.3	1.1	0.8	1.0	1.0	1.0	2.4	-0.5
Leg predicted mass (left)	0.2	1.1	4.0	0.9	1.2	-0.0	1.4	1.2	0.3	0.2	1.4	0.8	1.1	0.9	0.9	0.7	2.0	-0.7
Trunk fat mass	0.2	0.7	5.1	0.2	0.5	-0.2	0.4	2.3	-0.8	-0.6	1.2	-0.0	0.2	0.2	0.0	-0.2	1.4	0.1
Waist circumference	0.2	0.7	3.9	-0.2	0.4	-0.7	0.2	2.0	-1.2	-0.6	1.0	-0.3	-0.1	-0.1	-0.2	-0.5	1.5	-0.7
Nervous feelings	0.2	0.4	1.3	0.7	0.5	0.3	0.3	-0.9	1.1	0.4	-0.0	0.4	1.1	0.7	0.6	0.6	-0.3	0.2
Illnesses of siblings	0.2	0.2	1.6	0.2	-0.8	-0.7	-0.1	0.1	0.2	-0.2	-0.6	-0.1	-0.2	-0.1	0.1	0.0	0.2	-1.2
Arm fat percentage (right)	0.2	0.7	4.1	-0.3	0.1	-0.7	-0.3	2.0	-1.2	-1.1	0.8	-0.6	-0.1	-0.3	-0.5	-0.7	0.9	-0.1
Alcohol intake versus 10 years previously	0.2	0.3	1.0	-0.7	-0.7	-0.5	-0.9	-1.0	-0.4	-0.6	0.1	-0.3	-0.2	-0.4	-0.5	-0.7	-0.6	-0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.1	-0.7	-0.6	-0.3	-0.8	-1.5	0.6	-0.5	-0.9	-0.2	-0.2	-0.3	-0.3	-0.3	-1.3	-1.0
Lung cancer (father)	0.2	0.2	0.8	0.5	-0.0	0.0	-0.1	0.8	0.7	0.4	0.9	0.3	0.3	0.7	0.2	0.2	0.7	0.3
Arm fat mass (right)	0.2	0.7	3.5	-0.2	0.2	-0.9	0.0	1.9	-1.3	-1.1	0.8	-0.5	-0.1	-0.3	-0.4	-0.7	1.2	-0.6
Exposure to tobacco smoke at home	0.2	0.2	0.8	-0.1	0.1	-0.5	-0.4	-0.5	-0.8	-0.6	-0.1	-0.5	-0.6	-0.5	-0.3	-0.3	0.4	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.3	0.3	1.1	0.5	0.4	1.0	0.6	0.6	0.2	0.5	0.4	0.4	0.5	0.5	0.3	0.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	2.8	-0.1	-0.5	-0.1	-0.1	-1.7	0.6	-0.3	-0.9	-0.1	-0.2	-0.2	-0.1	0.0	-0.9	-0.6
Headache pain in last month	0.2	0.3	0.8	-0.4	0.4	-0.0	-0.4	0.5	-0.5	-0.4	-0.5	-0.6	-0.6	-0.4	-0.7	-0.5	-0.1	0.9
High blood pressure (siblings)	0.2	0.2	1.3	-0.4	0.2	0.1	-0.2	0.0	-0.6	-0.5	0.1	-0.4	-0.3	-0.3	-0.6	-0.5	-0.3	1.2
Body fat percentage	0.2	0.7	4.3	-0.5	-0.1	-0.6	-0.4	2.1	-1.3	-1.2	0.6	-0.7	-0.4	-0.4	-0.6	-0.8	0.7	0.1
Exposure to tobacco smoke outside home	0.2	0.3	0.8	-0.4	-0.1	-0.1	-0.4	-0.9	-0.8	-0.2	-0.3	-0.7	-0.6	-0.6	-0.8	-0.6	-0.2	0.9
Comparative body size at age 10	0.2	0.6	3.2	0.4	1.1	1.0	0.0	0.3	0.8	0.4	1.0	0.4	0.9	0.7	0.5	0.5	0.0	1.8
Worry too long after embarrassment	0.2	0.3	0.8	0.4	-0.0	0.5	0.1	-0.9	0.7	0.5	-0.0	0.6	0.5	0.5	0.8	0.7	-0.9	-0.1
Wheeze or whistling in the chest in last year	0.2	0.3	1.0	-0.7	-0.4	-0.9	-0.7	0.1	-0.5	-0.7	-0.4	-0.3	-0.5	-0.5	-0.3	-0.6	-0.6	-1.0
Number of children fathered	0.2	0.2	1.4	-0.3	-0.3	-0.7	-0.1	-0.1	-0.6	0.0	-0.3	-0.2	-0.4	-0.3	-0.3	-0.3	0.5	-1.2
Age at first live birth	0.2	0.4	2.0	0.3	0.4	0.7	-0.0	-1.4	1.1	0.2	0.0	0.4	0.5	0.4	0.2	0.5	-0.5	0.8
Emphysema/chronic bronchitis	0.2	0.2	1.3	0.2	-0.4	-0.6	-0.6	0.7	0.1	0.4	0.1	0.1	-0.3	0.1	0.4	0.1	-0.4	-1.1
Medication: Seretide 50 evohaler	0.2	0.2	0.6	0.5	-0.1	0.8	0.5	-0.7	0.3	0.2	0.1	0.3	0.4	0.4	0.2	0.4	0.2	0.7
Heart disease (mother)	0.2	0.2	0.7	0.0	0.6	0.6	0.4	0.3	-0.1	-0.1	0.8	0.2	0.4	0.3	0.3	0.2	0.3	0.9
Whole body fat mass	0.2	0.6	4.1	-0.2	0.1	-0.7	0.1	2.0	-1.2	-1.0	0.7	-0.4	-0.1	-0.2	-0.3	-0.5	1.0	-0.4
Leg fat mass (right)	0.2	0.9	2.9	-0.5	-0.3	-1.2	-0.4	1.7	-1.6	-1.4	0.2	-0.8	-0.6	-0.7	-0.8	-1.0	0.8	-0.8
Family relationship satisfaction	0.2	0.2	0.8	0.2	0.7	0.5	-0.1	-0.5	0.7	0.2	0.3	0.6	0.3	0.5	0.3	0.3	-0.3	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.5	1.0	0.8	0.6	1.2	0.3	0.4	0.5	0.1	0.5	0.6	0.4	0.5	0.6	0.5	0.7
Arm fat percentage (left)	0.2	0.7	4.7	-0.2	0.3	-0.6	-0.1	2.2	-1.1	-0.9	0.9	-0.4	-0.0	-0.1	-0.3	-0.6	1.0	-0.1
Loneliness, isolation	0.2	0.2	0.4	0.6	0.7	-0.0	0.3	0.2	0.4	0.6	0.4	0.5	0.3	0.4	0.6	0.4	0.5	-0.5
Breast cancer (self-reported)	0.2	0.2	0.9	-0.4	0.4	0.4	-0.4	-0.8	0.7	-0.1	-0.0	0.1	0.4	0.1	0.1	0.1	-0.9	0.6
Arm fat mass (left)	0.2	0.6	3.2	-0.3	0.2	-0.9	-0.0	1.8	-1.2	-1.1	0.8	-0.5	-0.1	-0.2	-0.3	-0.6	1.1	-0.6
Medication: Blood pressure	0.2	0.4	1.1	-1.1	-0.5	-0.0	-0.6	-1.0	-0.8	-0.5	-0.4	-0.5	-0.4	-0.5	-0.5	-0.6	-1.0	-0.6
Medication: Paracetamol	0.2	0.3	0.5	-0.7	-0.5	-0.7	-0.7	0.1	-0.2	-0.7	-0.2	-0.7	-0.3	-0.4	-0.6	-0.6	-0.2	-0.5
Fractured/broken bones in last 5 years	0.2	0.2	0.8	-0.2	-0.4	-0.5	-0.3	-0.9	-0.1	-0.7	-0.0	-0.2	-0.3	-0.2	-0.4	-0.4	0.1	-0.8
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.5	1.2	0.2	0.4	1.1	0.5	1.1	1.1	0.5	0.7	0.6	0.9	0.8	0.9	0.8	0.4
Pack years of smoking	0.2	0.2	1.2	-0.2	0.1	-0.4	-0.2	1.0	-1.1	-0.3	0.2	-0.5	-0.6	-0.4	-0.2	-0.4	0.2	-0.1
Leg fat mass (left)	0.2	0.8	3.7	-0.4	-0.1	-1.0	-0.2	1.9	-1.4	-1.2	0.5	-0.7	-0.4	-0.5	-0.6	-0.8	1.0	-0.7
Depressed Affect (Nagel 2018)	0.1	0.3	1.1	0.4	0.1	0.1	0.2	0.7	-0.0	0.8	0.5	0.4	0.2	0.3	0.5	0.6	1.0	-0.7
Alzheimer’s Disease (in father)	0.1	0.1	1.0	-0.0	0.1	0.4	-0.1	-0.7	0.4	0.2	0.1	-0.0	0.3	0.2	0.3	0.1	-1.0	0.3
Fasting Glucose	0.1	0.2	0.8	0.4	0.0	0.1	0.8	0.9	-0.1	0.4	0.5	0.3	0.1	0.1	0.2	0.3	0.1	-0.4
Lung FEV1/FVC ratio	0.1	0.6	3.7	0.1	0.7	-0.2	0.1	1.9	-0.8	-0.8	0.2	-0.7	-1.1	-0.3	-0.7	-0.5	0.6	1.1
Hair Pigment	0.1	1.8	4.2	-1.0	-2.0	-1.2	-1.2	-0.3	-1.7	-1.1	-1.7	-1.0	-1.8	-1.6	-1.4	-1.3	-1.4	-0.5
Tanning	0.1	1.1	4.2	-0.7	-0.3	-0.7	-1.7	-1.1	-0.3	-1.4	-1.3	-0.6	-1.1	-0.8	-0.9	-1.0	-2.0	0.0
Hand grip strength (left)	0.1	0.3	0.7	0.1	-0.6	-0.7	-0.6	-0.7	-0.1	-0.7	-0.9	-0.3	-0.5	-0.5	-0.5	-0.4	-0.6	-0.3
Number of treatments/medications taken	0.1	0.1	0.6	0.2	0.3	0.2	-0.2	-0.0	0.5	-0.8	0.2	0.4	0.6	0.3	0.2	0.2	0.2	0.0
Hearing difficulty/problems: Yes	0.1	0.2	0.5	-0.6	-0.7	-0.3	-0.4	-0.4	0.2	-0.7	-0.3	-0.2	-0.4	-0.2	-0.6	-0.5	-0.6	-0.1
Systolic blood pressure, automated reading	0.1	0.4	1.5	-1.0	-0.1	0.0	-0.4	-1.2	-0.8	-1.2	0.0	-0.3	0.1	-0.4	-0.3	-0.4	-0.6	-0.3
Severe depression (siblings)	0.1	0.1	0.8	0.0	0.2	0.2	-0.3	-0.1	0.4	-0.0	0.0	-0.0	0.1	0.2	-0.1	-0.1	-0.9	0.9
Current tobacco smoking	0.1	0.1	0.7	-0.4	0.8	0.0	-0.4	0.9	-0.3	-0.4	0.0	-0.1	-0.1	-0.1	-0.2	-0.2	-0.1	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	-0.0	0.3	-0.4	-0.3	0.6	-0.5	0.1	0.0	-0.2	-0.1	-0.2	-0.2	-0.2	0.4	-0.4
Age when periods started (menarche)	0.1	0.1	0.5	-0.5	0.2	-0.1	-0.4	-0.7	-0.3	-0.2	-0.2	-0.4	-0.4	-0.3	-0.3	-0.4	-0.5	0.1
Medication: Atenolol	0.1	0.2	0.6	-0.3	-0.3	-0.3	-0.5	-0.8	-0.1	-0.6	-0.6	-0.2	0.2	-0.2	-0.2	-0.2	-0.4	-0.5
Chronic bronchitis/emphysema (father)	0.1	0.1	0.4	-0.2	-0.2	-0.0	-0.2	-0.5	-0.0	0.3	-0.3	-0.2	0.2	-0.2	0.1	0.0	-0.6	-0.1
High blood pressure (mother)	0.1	0.1	0.6	-0.4	-0.1	0.2	-0.2	-0.8	-0.5	-0.3	-0.1	-0.3	0.1	-0.3	-0.0	-0.0	-0.6	0.1
Hearing difficulty/problems with background noise	0.1	0.1	0.6	0.1	0.2	0.3	0.2	-0.4	0.7	0.0	0.2	0.4	0.3	0.4	0.2	0.3	0.1	0.2
Heart attack	0.1	0.1	0.4	0.1	0.5	0.2	-0.1	0.4	0.4	-0.0	0.3	0.4	0.7	0.4	0.3	0.2	0.1	0.6
Medication: Ramipril	0.1	0.1	0.5	-0.4	0.0	0.5	-0.1	-0.7	0.3	-0.3	-0.1	0.2	0.1	0.1	-0.1	-0.1	-0.7	0.5
Medication: Simvastatin	0.1	0.2	1.6	0.4	0.1	-0.0	-0.0	1.3	-0.2	-0.3	0.3	0.1	0.4	0.0	-0.1	-0.0	0.7	0.4
Weight	0.1	0.5	2.0	0.1	0.4	-0.7	0.5	1.4	-0.7	-0.8	1.0	-0.1	0.3	0.1	0.0	-0.3	1.3	-0.7
Trunk fat-free mass	0.1	0.5	1.7	0.8	0.7	-0.3	1.3	0.0	0.3	-0.1	0.7	0.6	0.8	0.6	0.6	0.5	1.3	-1.0
Hip circumference	0.1	0.5	2.4	0.1	0.5	-0.4	0.5	1.4	-0.2	-0.7	1.2	0.2	0.3	0.3	0.1	-0.1	1.5	-0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.4	1.2	0.9	0.2	0.9	-0.2	1.0	0.6	0.0	0.3	0.4	0.5	0.4	0.5	0.6	0.9
Pulse wave Arterial Stiffness index	0.1	0.1	0.6	-0.4	-0.6	-0.0	-0.2	-0.2	-0.1	-0.0	-0.3	-0.2	-0.4	-0.2	-0.2	-0.3	-0.8	0.0
Trunk predicted mass	0.1	0.5	1.6	0.8	0.7	-0.3	1.3	-0.1	0.4	-0.1	0.6	0.6	0.8	0.6	0.7	0.5	1.2	-0.9
Glaucoma (self-reported)	0.1	0.2	0.6	-0.3	-0.8	-0.3	-0.2	-0.2	-0.3	-0.3	-0.5	-0.4	-0.3	-0.5	-0.5	-0.4	0.3	-0.5
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.9	-0.3	0.2	0.6	0.1	0.1	-0.1	-0.5	0.7	0.2	0.1	0.3	0.1	0.1	0.1	0.9
Medication: Amlodipine	0.1	0.2	0.8	-0.1	-0.1	-0.1	0.2	0.9	-0.8	0.4	0.3	-0.0	-0.1	-0.2	-0.1	-0.1	0.8	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.3	-0.6	-0.2	-0.3	0.1	-0.6	0.0	-0.3	-0.2	-0.2	-0.1	-0.2	-0.2	-0.3	-0.2	-0.6
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.8	0.1	-0.1	0.1	0.1	0.9	-0.4	0.2	0.4	0.1	-0.1	0.0	0.1	0.0	0.4	0.2
Arm fat-free mass (right)	0.1	0.3	1.6	0.3	0.4	-0.7	0.8	0.5	-0.3	-0.5	0.5	0.2	0.1	0.2	0.2	0.0	1.1	-1.3
Number of full brothers	0.1	0.2	0.7	0.1	0.6	0.3	0.2	0.8	-0.4	-0.6	0.2	0.2	-0.3	-0.0	-0.2	-0.1	-0.0	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.9	0.0	0.4	-0.6	-0.3	0.9	-0.3	-0.2	-0.1	0.1	-0.2	-0.2	0.1	-0.1	0.3	-0.9
Eye problems/disorders: None of the above	0.1	0.1	0.4	0.0	0.6	-0.1	0.2	0.3	-0.3	-0.4	0.3	0.0	0.1	0.0	0.1	0.1	0.3	-0.4
Migraine (self-reported)	0.1	0.1	0.6	-0.1	0.2	-0.2	-0.3	0.4	-0.2	-0.3	0.0	-0.3	-0.1	-0.1	-0.3	-0.2	0.8	-0.4
Arm predicted mass (right)	0.1	0.3	1.8	0.1	0.2	-0.8	0.6	0.2	-0.4	-0.7	0.3	0.1	0.1	0.0	0.1	-0.1	0.9	-1.4
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.4	-0.5	0.1	-0.6	-0.2	0.1	-0.3	0.0	-0.5	-0.4	-0.2	-0.3	-0.2	-0.3	-0.3	-0.6
Whole body fat-free mass	0.1	0.8	2.5	0.9	0.9	-0.1	1.4	0.6	0.4	-0.0	1.1	0.7	0.9	0.8	0.8	0.6	1.6	-0.8
Mood swings	0.1	0.1	0.2	0.3	-0.1	0.1	0.4	-0.0	0.5	0.0	0.2	0.4	0.3	0.3	0.4	0.4	0.4	-0.2
Long-standing illness, disability or infirmity	0.1	0.1	0.6	0.2	0.2	-0.3	-0.3	0.7	-0.0	-0.8	-0.3	-0.1	-0.0	-0.1	0.0	-0.1	-0.3	-0.1
Eye problems/disorders: Cataract	0.1	0.2	0.4	-0.5	-0.6	-0.2	-0.3	-0.3	-0.3	0.1	-0.4	-0.3	-0.5	-0.4	-0.4	-0.4	-0.6	0.5
Back pain experienced in last month	0.1	0.1	0.6	-0.2	0.0	-0.1	0.2	-0.3	-0.8	-0.4	-0.1	-0.6	-0.5	-0.4	-0.4	-0.3	0.2	-0.3
Medication: Gliclazide	0.1	0.2	0.7	0.1	-0.6	-0.2	-0.2	0.5	-0.5	0.5	-0.0	-0.3	-0.3	-0.3	-0.2	-0.1	0.8	-0.3
Smoking status: Current	0.1	0.2	1.6	-0.1	1.0	0.2	-0.0	1.3	-0.1	-0.0	0.4	0.1	0.1	0.2	0.1	0.1	0.3	0.4
Whole body water mass	0.1	0.8	2.8	0.9	0.9	-0.2	1.4	0.6	0.4	0.0	1.1	0.8	0.9	0.8	0.8	0.6	1.7	-0.9
Number of self-reported non-cancer illnesses	0.1	0.2	0.8	0.4	0.8	0.3	0.1	0.9	0.4	0.3	0.6	0.6	0.6	0.5	0.5	0.3	0.2	0.1
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.5	0.2	0.2	0.4	0.5	0.4	-0.2	0.1	0.5	0.2	0.2	0.0	-0.0	0.1	0.6	0.7
Eye problems/disorders: Glaucoma	0.1	0.2	0.5	-0.5	-0.7	-0.1	-0.3	-0.6	-0.2	-0.1	-0.3	-0.5	-0.3	-0.4	-0.6	-0.4	0.2	-0.1
Medication: Bendroflumethiazide	0.1	0.1	0.5	-0.0	0.3	0.6	-0.1	-0.3	0.2	0.3	0.3	0.4	0.5	0.3	0.2	0.2	-0.2	0.7
Medication: Atorvastatin	0.1	0.1	0.6	-0.2	-0.4	-0.1	-0.6	-0.8	-0.1	-0.2	-0.2	0.0	-0.1	-0.2	0.0	-0.0	-0.3	-0.8
Basal metabolic rate	0.1	0.6	2.6	0.7	0.8	-0.4	1.1	0.9	0.0	-0.3	1.1	0.5	0.7	0.6	0.6	0.3	1.6	-0.9
Arm fat-free mass (left)	0.1	0.3	1.4	0.1	0.1	-0.8	0.6	0.2	-0.5	-0.7	0.4	-0.1	0.1	0.0	0.0	-0.2	0.9	-1.2
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.5	-0.3	-0.6	-0.3	-0.7	-0.3	-0.4	-0.4	-0.4	-0.4	-0.2	-0.4	-0.5	-0.4	-0.3	0.1
Ever depressed for a whole week	0.1	0.1	0.4	0.2	0.5	-0.1	-0.0	0.4	0.4	0.3	0.1	0.2	0.4	0.2	0.3	0.3	0.4	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.7	-0.1	0.6	0.1	0.4	0.9	0.0	-0.3	0.4	0.1	-0.0	0.2	0.1	0.0	0.6	0.3
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.4	0.0	0.4	0.2	-0.0	0.3	0.2	0.1	0.2	0.3	0.6	0.3	0.3	0.1	0.0	0.5
Impedance of whole body	0.1	0.4	3.7	0.4	-0.1	1.1	0.2	-0.1	0.5	0.7	-0.2	0.2	-0.1	0.3	0.1	0.4	-0.5	1.9
Arm predicted mass (left)	0.1	0.4	1.8	0.2	0.2	-0.8	0.7	0.4	-0.5	-0.7	0.5	0.0	0.1	0.0	0.1	-0.1	1.1	-1.3
Bipolar Disorder or Schizophrenia	0.0	0.1	0.4	0.2	0.2	0.2	-0.1	0.4	0.1	0.2	-0.0	0.3	0.1	0.1	-0.1	0.1	0.1	0.7
Depression (Nagel 2018)	0.0	0.1	0.2	-0.1	-0.1	-0.5	-0.4	0.2	-0.2	-0.0	-0.2	-0.1	-0.1	-0.2	-0.2	-0.3	-0.3	-0.4
Lupus	0.0	0.0	0.2	0.1	0.4	0.0	-0.0	0.0	0.0	-0.0	-0.1	-0.1	0.1	0.2	0.0	0.0	-0.1	-0.2
Heel T-Score	0.0	0.3	0.9	-0.1	0.3	-0.4	-0.8	0.2	-0.9	-0.5	0.2	-0.6	-0.5	-0.3	-0.5	-0.4	0.5	0.9
Hypothyroidism (self reported)	0.0	0.1	0.4	-0.6	-0.1	0.3	0.1	-0.1	-0.2	-0.6	0.4	0.1	-0.1	-0.0	-0.1	-0.1	-0.2	0.5
Tense / ‘highly strung’	0.0	0.1	0.3	0.2	0.0	0.1	0.2	-0.2	0.1	0.2	-0.0	0.3	-0.1	0.1	0.4	0.2	-0.6	-0.5
Pulse wave reflection index	0.0	0.0	0.1	0.2	-0.2	-0.0	0.3	0.2	-0.2	0.2	-0.3	-0.0	-0.1	-0.2	-0.1	-0.0	0.1	0.2
Medication: Lisinopril	0.0	0.1	0.2	-0.2	-0.4	0.1	-0.5	0.0	-0.4	-0.0	-0.4	-0.1	-0.0	-0.3	-0.1	-0.1	-0.4	0.1
Diastolic blood pressure, automated reading	0.0	0.1	0.6	-0.5	0.6	0.3	0.3	-0.7	-0.4	-0.5	0.4	0.0	0.1	-0.0	0.1	0.1	0.1	-0.3

Hub : Genes

SMG5

Models

Trait associations