Hub : Genes

SMTN

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.117 0.043 0.00061 0.058 0.025 0.033 0.037 0.050 1.3e-07 0.00042 6.1e-05 2.5e-05 9.1e-07
2 GTEx Cells Transformed fibroblasts 0.051 0.026 0.00970 -0.002 NA -0.003 NA 0.004 5.6e-01 NA 7.1e-01 NA 1.5e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.5 0.7 0.9 -1.0 0.7
Bipolar Disorder or Schizophrenia 0.6 1.5 3.0 -0.2 1.7
Depressed Affect (Nagel 2018) 0.4 0.8 1.4 0.4 -1.2
Depression (Nagel 2018) 1.0 1.6 3.1 1.8 0.0
Intelligence (Savage-Jansen 2018) 0.1 0.4 0.9 -0.1 -0.9
Neuroticism (Nagel 2018) 1.6 3.9 7.7 -0.1 -2.8
Schizophrenia (2018) 0.7 1.4 2.7 0.3 1.7
Schizophrenia vs Biploar Disorder 0.1 0.1 0.1 0.4 -0.3
Worry (Nagel 2018) 1.3 2.8 5.1 -0.7 -2.3
Alzheimer’s Disease (in mother) 0.5 0.6 1.1 -1.0 -0.3
Alzheimer’s Disease (in father) 1.5 1.6 2.6 -0.8 1.6
Alzheimer’s Disease (including proxy) 0.3 0.5 0.7 -0.9 0.5
Crohns Disease (2017) 0.7 1.6 2.6 -1.6 0.7
Irritable Bowel Disease (IBD) 0.1 0.1 0.2 -0.4 -0.4
Ulcerative Colitis (UC) 1.0 1.9 2.2 1.3 -1.5
Major Depression (MDD) 0.6 0.8 1.0 0.7 -1.0
Reaction Time 2.9 5.6 10.9 0.6 3.3
Verbal and Numeric Reasoning (VNR) 0.3 0.7 1.4 -0.1 -1.2
Breast Cancer 0.9 2.2 4.2 -2.1 -0.4
Ovarian Cancer 0.7 1.0 1.6 -1.3 -0.6
Prostate Cancer 4.1 5.7 8.0 1.9 2.8
Age at First Birth 0.2 0.2 0.3 -0.4 0.6
Bipolar Disorder (2011) 0.2 0.2 0.4 0.0 0.6
Body Mass Index (BMI) (2010) 0.1 0.1 0.1 -0.3 0.4
Coronary Artery Disease (CAD) 0.3 0.3 0.6 -0.8 0.1
Crohns Disease (2012) 0.1 0.1 0.1 -0.3 0.3
Mean Putamen Volume 2.5 2.8 5.3 -0.5 -2.3
Fasting Glucose 0.6 0.7 1.2 -0.4 -1.1
HbA1C 0.7 0.8 1.4 -0.5 -1.2
HDL Cholesterol 0.2 0.4 0.8 -0.9 -0.1
LDL Cholesterol 0.2 0.3 0.6 0.8 -0.2
Lupus 0.1 0.2 0.3 -0.5 0.3
Neuroticism (2016) 0.8 1.1 1.4 -0.9 -1.2
Primary Biliary Cirrhosis 0.6 0.9 1.6 -1.3 -0.4
Rheumatoid Arthritis 1.1 1.6 2.7 -1.6 0.6
Schizophrenia (2014) 0.4 0.8 1.5 -0.3 1.2
Triglycerides 1.1 1.8 3.3 1.8 -0.6
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.3 -0.1 -0.5
Ulcerative Colitis 0.3 0.4 0.7 0.8 -0.2
Blood Eosinophil Count 4.2 32.0 62.9 -1.1 7.9
Blood Platelet Count 0.3 3.0 5.1 -2.2 1.0
Blood Red Count 0.4 3.8 4.0 -2.0 -1.9
Blood White Count 1.1 8.3 15.4 1.1 -3.9
Heel T-Score 2.4 18.8 33.5 2.0 5.8
BMI 0.4 2.4 3.5 1.1 1.9
Height 0.4 8.3 11.8 -3.4 2.2
Waist Hip Ratio (WHR) 2.2 10.0 19.2 0.9 -4.4
Systolic Blood Pressure 0.5 2.3 4.5 0.1 -2.1
Smoking Status 1.6 3.9 7.8 -0.3 -2.8
Allergy or Eczema 1.6 4.1 6.9 -2.6 1.1
Cardiovascular Disease 0.1 0.3 0.5 0.2 -0.7
Hypothyroidism (self reported) 0.7 1.7 2.8 -0.8 1.7
Respiratory disease 0.3 0.8 1.1 -1.1 0.6
Type 2 Diabetes (T2D) (2018) 0.1 0.2 0.2 0.4 0.5
Lung FEV1/FVC ratio 0.4 2.3 3.3 1.1 1.8
Lung FVC 1.0 5.2 5.7 -2.4 2.2
Neuroticism 2.3 5.5 10.4 -0.7 -3.2
Chronotype (morning person) 0.8 1.8 2.6 1.6 1.0
Hair Pigment 0.2 4.6 8.7 -0.7 -2.9
Tanning 0.2 2.9 5.9 -2.4 0.0
Hand grip strength (left) 1.7 4.6 7.3 -1.4 2.7
Number of treatments/medications taken 0.2 0.3 0.4 -0.6 -0.5
Average weekly spirits intake 0.2 0.3 0.3 0.5 0.6
Sensitivity / hurt feelings 0.9 1.6 3.2 0.1 -1.8
Frequency of depressed mood in last 2 weeks 0.0 0.0 0.0 0.2 0.2
Hearing difficulty/problems: Yes 0.0 0.1 0.1 -0.3 -0.2
Relative age of first facial hair 0.7 1.4 2.7 0.3 -1.7
Other serious medical condition/disability diagnosed by doctor 1.2 1.5 2.9 -0.3 -1.7
Ever used hormone-replacement therapy (HRT) 1.3 1.7 2.2 -1.5 -1.1
Ever had hysterectomy (womb removed) 1.6 1.8 3.5 0.5 1.9
Systolic blood pressure, automated reading 0.4 1.0 2.1 0.1 -1.4
Eye problems/disorders: Diabetes related eye disease 0.1 0.2 0.2 0.5 0.3
Angina 0.8 1.1 1.6 1.3 0.8
Medication for hormone replacement therapy 1.9 2.1 2.8 -1.1 1.7
Vitamin and mineral supplements 0.0 0.0 0.0 -0.1 -0.0
Supplements: Zinc 1.2 1.3 2.5 1.6 -0.1
Medication: Co-codamol 0.9 1.1 1.6 0.8 -1.3
Medication: Metformin 2.8 4.0 4.0 2.0 -2.0
Diabetes (father) 1.5 1.9 2.4 1.2 -1.6
Diabetes (mother) 1.5 1.9 3.8 2.0 0.3
Severe depression (siblings) 3.4 3.8 7.3 0.5 2.7
Pack years adult smoking proportion 0.3 0.5 1.0 -1.0 0.3
Impedance of leg (right) 1.4 6.7 13.4 -0.0 -3.7
Leg fat-free mass (left) 0.5 2.7 5.3 -0.4 2.3
Trunk fat percentage 1.0 4.0 7.7 0.4 -2.8
Hand grip strength (right) 2.0 5.4 8.1 -1.6 2.9
Townsend deprivation index at recruitment 1.1 1.6 2.2 1.5 -1.0
Current tobacco smoking 2.4 3.9 7.6 0.5 -2.7
Average weekly fortified wine intake 0.3 0.4 0.6 0.4 -0.8
Maternal smoking around birth 0.2 0.3 0.5 -0.4 -0.7
Fed-up feelings 0.3 0.6 1.0 -0.5 1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.3 0.5 -0.2
Relative age voice broke 1.0 1.6 3.1 -0.0 -1.8
Taking other prescription medications 0.4 0.7 1.1 -1.1 -0.5
Age when periods started (menarche) 2.8 6.7 11.2 -1.5 -3.4
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 0.6 -0.8 0.1
Heel bone mineral density (BMD) T-score, automated (left) 4.1 9.2 15.0 1.9 3.9
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 3.3 1.8 -0.2
Qualifications: CSEs or equivalent 0.1 0.2 0.3 0.2 0.6
Serious illness, injury or assault to yourself 0.4 0.5 0.7 0.6 -0.8
High blood pressure 1.0 2.9 5.5 0.6 -2.3
Hayfever, allergic rhinitis or eczema 0.7 1.5 2.2 -1.5 0.9
Multivitamins +/- minerals 0.0 0.0 0.1 -0.1 0.3
Stomach or abdominal pain in last month 1.1 1.3 2.1 -1.5 -0.7
Supplements: Glucosamine 0.8 1.0 1.9 -0.4 1.4
Diverticular disease/diverticulitis (self-reported) 1.2 1.5 1.6 -1.3 1.2
Medication: Atenolol 0.1 0.1 0.2 0.5 -0.3
Medication: Levothyroxine sodium 0.7 1.1 2.1 -1.5 -0.3
Sitting height 1.0 7.0 14.1 0.2 3.7
Chronic bronchitis/emphysema (father) 0.5 0.6 0.6 0.8 -0.8
High blood pressure (mother) 0.2 0.3 0.4 0.4 -0.6
Body mass index (BMI) 0.2 1.0 1.6 1.3 0.6
Impedance of leg (left) 1.4 7.0 13.9 -0.4 -3.7
Leg predicted mass (left) 0.5 2.7 5.3 -0.4 2.3
Trunk fat mass 0.3 1.5 2.6 0.5 -1.6
Waist circumference 0.7 2.6 3.6 1.9 -1.2
Number of incorrect matches in round 0.3 0.5 0.7 0.6 0.9
Past tobacco smoking 0.7 1.3 2.5 -0.2 1.6
Alcohol usually taken with meals 3.4 5.4 8.1 2.8 1.7
Nervous feelings 2.7 5.0 7.6 -2.8 -1.5
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.2 -0.2 -0.4
Hearing difficulty/problems with background noise 0.0 0.0 0.0 -0.1 -0.2
Hair/balding pattern: Pattern 2 1.9 2.4 3.5 1.2 -1.9
Had menopause 0.5 0.6 0.6 -0.8 -0.8
Had other major operations 2.5 3.0 4.7 -2.2 1.2
Forced vital capacity (FVC) 2.0 7.9 8.1 -2.9 2.8
Heel bone mineral density (BMD) T-score, automated (right) 3.1 7.1 10.7 1.9 3.3
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 1.4 0.6 -1.2
Qualifications: None of the above 0.3 0.6 1.1 -0.3 -1.1
Financial difficulties in last 2 years 0.2 0.3 0.3 -0.5 0.6
Mouth/teeth dental problems 0.2 0.2 0.4 -0.6 -0.3
Heart attack 1.1 1.4 2.8 1.7 -0.2
Allergy 0.9 2.1 4.0 2.0 -0.4
Pain all over the body in last month 1.7 1.8 3.4 -0.5 -1.8
Diabetes (self-reported) 1.2 1.8 2.7 1.0 -1.6
Hayfever/allergic rhinitis (self-reported) 1.3 1.8 3.4 -0.4 1.8
Medication: Ramipril 1.1 1.5 2.9 -0.2 1.7
Medication: Simvastatin 0.3 0.4 0.8 0.3 -0.9
Fluid intelligence score 0.3 0.6 0.9 -1.0 -0.5
Illnesses of siblings 0.8 1.2 2.4 0.0 1.5
Neuroticism score 0.7 1.4 1.7 -1.3 -1.1
Weight 0.1 0.7 1.2 0.4 1.1
Impedance of arm (right) 1.5 7.0 12.8 -1.1 -3.6
Arm fat percentage (right) 0.4 1.4 1.6 1.1 -1.3
Trunk fat-free mass 1.3 7.2 14.4 -0.2 3.8
Hip circumference 0.2 0.9 1.7 1.3 0.2
Time employed in main current job 0.2 0.2 0.4 -0.6 0.3
Alcohol intake versus 10 years previously 1.6 2.4 3.2 -1.8 1.3
Father’s age at death 2.9 3.8 7.2 -0.7 -2.7
Worrier / anxious feelings 0.8 1.4 1.6 -1.1 -1.3
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.3 0.0 -1.1
Falls in the last year 0.4 0.5 0.7 -0.8 -0.6
Hair/balding pattern: Pattern 3 0.3 0.4 0.6 -0.4 -0.8
Number of live births 0.5 0.8 1.1 -0.7 1.0
Forced expiratory volume in 1-second (FEV1) 1.8 5.9 8.7 -1.8 2.9
Pulse rate 0.4 0.6 0.7 -0.8 -0.8
Happiness 0.2 0.2 0.3 -0.4 -0.5
Noisy workplace 6.8 8.3 12.7 2.0 3.6
Qualifications: A levels/AS levels or equivalent 0.5 1.0 1.4 -1.2 -0.8
Serious illness, injury or assault of a close relative in last 2 years 0.0 0.0 0.0 0.2 0.0
Mouth/teeth dental problems: Dentures 0.5 0.8 1.0 1.0 -0.8
Asthma 0.7 1.3 2.2 -1.5 0.6
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 1.6 -1.1 1.3
Medication: Cholesterol lowering 1.1 1.8 3.5 1.9 0.3
Depression (self-reported) 1.5 1.8 2.2 -1.5 -1.1
Medication: Lansoprazole 1.0 1.1 1.8 -1.3 -0.6
Prospective memory result 0.9 1.1 1.2 -1.0 -1.1
Lung cancer (father) 1.7 2.0 2.0 1.4 -1.4
Illnesses of mother 0.7 0.8 1.6 -1.3 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 1.9 6.0 8.8 -1.8 3.0
Pulse wave Arterial Stiffness index 1.3 1.6 3.1 0.1 -1.8
Impedance of arm (left) 2.3 10.6 20.3 -1.0 -4.5
Arm fat mass (right) 0.1 0.5 0.9 0.9 -0.2
Trunk predicted mass 1.3 7.4 14.7 -0.2 3.8
Standing height 0.2 2.4 3.6 -1.9 1.1
Length of working week for main job 0.1 0.1 0.1 -0.2 0.3
Exposure to tobacco smoke at home 0.1 0.1 0.2 -0.4 0.2
Breastfed as a baby 2.9 3.7 7.3 -2.7 -0.2
Tense / ‘highly strung’ 0.0 0.1 0.1 -0.2 -0.2
Seen doctor (GP) for nerves, anxiety, tension or depression 1.4 2.1 2.9 1.7 -1.2
Hair/balding pattern: Pattern 4 0.3 0.6 1.3 0.2 1.1
Birth weight of first child 2.0 3.7 6.4 1.0 2.5
Peak expiratory flow (PEF) 1.7 3.9 7.8 -0.1 2.8
Pulse wave reflection index 0.9 1.2 1.9 0.7 -1.4
Ever highly irritable/argumentative for 2 days 0.3 0.4 0.8 0.1 -0.9
Loud music exposure frequency 1.0 1.1 1.6 1.3 0.7
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 1.2 -0.7 -1.1
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 0.7 -0.9 0.2
Blood clot in the leg (DVT) 1.0 1.3 2.4 -0.5 1.5
Medication: Paracetamol 0.4 0.7 1.4 -1.2 0.0
Headache pain in last month 0.5 0.8 1.4 -1.2 0.3
Medication for cholesterol, blood pressure or diabetes 0.4 0.6 1.0 -1.0 0.6
Glaucoma (self-reported) 3.3 3.9 7.4 0.6 -2.7
Gout (self-reported) 0.7 0.9 1.8 -0.3 -1.3
Hypothyroidism/myxoedema (self-reported) 0.4 0.8 0.9 -0.8 1.0
Medication: Amlodipine 0.1 0.1 0.2 0.1 -0.4
Medication: Ventolin 100micrograms inhaler 2.2 2.8 5.3 -2.3 -0.5
Birth weight 1.6 3.5 4.2 1.7 2.0
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.1 -0.3 0.1
High blood pressure (siblings) 0.0 0.1 0.1 0.1 -0.3
Forced vital capacity (FVC), Best measure 2.1 7.7 9.8 -3.1 2.4
Body fat percentage 0.9 3.5 5.7 1.1 -2.4
Leg fat percentage (right) 0.9 3.3 3.4 1.8 -1.8
Arm fat-free mass (right) 0.8 4.1 8.3 -0.2 2.9
Exposure to tobacco smoke outside home 0.0 0.1 0.1 0.3 0.1
Comparative body size at age 10 0.2 0.5 0.8 0.4 0.9
Number of full brothers 0.1 0.1 0.2 0.1 -0.5
Worry too long after embarrassment 0.1 0.1 0.2 0.1 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 1.0 1.7 0.5 -1.3
Wheeze or whistling in the chest in last year 1.7 3.0 3.2 -1.8 -1.7
Number of children fathered 1.5 1.6 2.3 1.0 1.5
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.4 0.6 -0.2
Age at first live birth 0.7 1.2 1.6 -0.9 1.3
Pulse wave peak to peak time 1.7 2.0 4.0 -0.2 2.0
Health satisfaction 0.2 0.2 0.4 0.1 0.6
Shortness of breath walking on level ground 0.3 0.3 0.5 0.4 -0.7
Qualifications: College or University degree 0.7 2.3 4.3 -0.5 2.1
Eye problems/disorders: None of the above 0.8 0.9 1.3 -0.7 1.1
Mouth/teeth dental problems: Loose teeth 0.6 0.7 1.3 0.1 -1.2
Emphysema/chronic bronchitis 2.7 3.1 5.0 -1.1 -2.2
Medication for pain relief, constipation, heartburn 0.9 1.6 2.1 1.5 -1.1
Neck or shoulder pain in last month 0.3 0.4 0.6 -0.8 -0.5
Medication: Blood pressure 1.2 2.1 4.0 0.5 -2.0
Angina (self-reported) 0.9 1.2 2.2 1.5 0.6
Migraine (self-reported) 0.1 0.1 0.1 0.3 0.3
Medication: Ibuprofen 1.0 1.2 1.7 -1.3 0.9
Medication: Allopurinol 0.2 0.3 0.6 0.2 -0.8
Medication: Omeprazole 0.9 1.1 2.2 -1.5 0.1
Medication: Seretide 50 evohaler 0.7 0.8 1.6 -1.3 -0.1
Mean time to correctly identify matches 2.0 3.9 7.7 -0.2 2.8
Heart disease (mother) 0.9 1.1 2.0 -0.3 1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 0.4 0.7 0.4
Whole body fat mass 0.2 0.9 1.5 0.6 -1.2
Leg fat mass (right) 0.2 0.9 1.2 1.1 -0.8
Arm predicted mass (right) 0.7 3.4 6.8 -0.2 2.6
Pulse rate, automated reading 1.1 3.7 7.2 -0.4 -2.7
Alcohol intake frequency. 0.2 0.5 0.7 0.5 0.8
Comparative height size at age 10 0.4 1.9 2.3 -1.3 1.5
Number of full sisters 0.0 0.0 0.0 -0.1 -0.2
Suffer from ‘nerves’ 1.3 2.0 3.9 0.5 -2.0
Overall health rating 0.4 0.8 1.7 0.0 -1.3
Chest pain or discomfort 0.4 0.6 1.0 1.0 -0.3
Had major operations 2.4 2.8 4.3 2.1 1.2
Age at last live birth 1.6 2.3 3.2 -1.8 1.1
Family relationship satisfaction 0.5 0.7 1.3 0.2 -1.1
Leg pain on walking 0.7 0.9 1.6 -0.4 -1.3
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.2 0.0 0.4
Commuting to job workplace: Car/motor vehicle 0.7 0.8 1.6 -1.3 -0.2
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 1.4 0.5 -1.2
Medication: Aspirin 0.2 0.3 0.4 -0.7 -0.3
Supplements: Vitamin C 0.7 0.8 1.6 1.3 0.2
Knee pain experienced in last month 2.1 3.3 5.5 -1.0 -2.4
Hypertension (Self-reported) 0.9 2.6 5.1 0.4 -2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 4.4 5.1 10.2 -3.2 0.3
Illnesses of father: Heart disease 0.3 0.4 0.8 -0.3 0.9
Illnesses of siblings: Diabetes 1.0 1.2 1.9 1.4 -0.7
Smoking status: Previous 0.5 0.7 1.4 -0.3 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 1.1 2.3 4.5 -0.3 2.1
Whole body fat-free mass 1.0 5.9 11.7 -0.4 3.4
Leg fat-free mass (right) 0.6 3.3 6.2 -0.7 2.5
Arm fat percentage (left) 0.6 2.2 3.1 1.2 -1.8
Average weekly red wine intake 0.8 1.2 1.4 1.2 -1.0
Handedness (chirality/laterality): Left-handed 0.1 0.2 0.3 -0.6 -0.1
Mood swings 2.4 4.3 7.0 -2.6 -1.3
Loneliness, isolation 0.0 0.1 0.1 -0.1 -0.4
Long-standing illness, disability or infirmity 0.6 0.9 1.3 -0.6 -1.1
Ever had bowel cancer screening 1.5 1.7 3.4 0.0 -1.9
Diabetes diagnosed by doctor 1.1 1.8 2.1 1.5 -1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.3 -0.5 -0.2
Friendships satisfaction 0.4 0.5 0.9 0.9 -0.2
Qualifications: nursing, teaching 0.4 0.6 1.0 0.5 1.0
Commuting to job workplace: Walk 2.0 2.1 4.2 2.1 0.3
Eye problems/disorders: Cataract 1.6 1.8 2.6 1.1 -1.6
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 1.2 1.1 0.0
Medication for cholesterol 0.3 0.4 0.7 0.8 -0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 0.7 0.8 -0.7
Back pain experienced in last month 0.8 1.2 2.0 -1.4 0.6
Mineral and other dietary supplements 0.3 0.4 0.9 -0.1 -0.9
Breast cancer (self-reported) 0.8 0.9 1.4 0.7 -1.2
Asthma (self-reported) 0.7 1.4 1.9 -1.4 0.9
Osteoporosis (self-reported) 2.3 2.8 5.5 -0.3 -2.4
Osteoarthritis (self-reported) 3.2 4.1 5.5 -2.3 -1.7
Medication: Aspirin 0.2 0.2 0.3 -0.4 -0.5
Medication: Gliclazide 0.8 0.9 1.9 0.0 -1.4
Illnesses of father: None of the above (group 1) 0.1 0.2 0.2 -0.4 -0.4
Smoking status: Current 2.1 3.3 6.6 0.2 -2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.8 2.3 -1.1 1.5
Whole body water mass 1.1 6.2 12.3 -0.3 3.5
Leg predicted mass (right) 0.6 3.1 5.8 -0.7 2.4
Arm fat mass (left) 0.1 0.4 0.7 0.9 -0.2
Number of self-reported non-cancer illnesses 0.6 1.0 2.0 -1.4 -0.1
Average weekly champagne plus white wine intake 0.9 1.2 2.4 0.3 1.5
Miserableness 0.2 0.3 0.6 0.8 -0.1
Guilty feelings 0.5 0.7 0.8 -0.8 -0.9
Wears glasses or contact lenses 0.4 0.4 0.8 0.0 -0.9
Ever taken oral contraceptive pill 0.7 0.8 1.5 -0.4 1.2
Hearing aid user 1.1 1.3 1.5 1.0 1.2
Mother’s age at death 0.3 0.4 0.5 -0.7 0.5
Financial situation satisfaction 3.8 4.7 8.8 0.7 -3.0
Tinnitus: Yes, now most or all of the time 1.1 1.3 1.7 -1.3 1.0
Commuting to job workplace: Public transport 1.8 2.1 3.2 1.0 -1.8
Eye problems/disorders: Glaucoma 1.2 1.4 2.1 1.4 -0.9
Medication: Blood pressure 0.2 0.4 0.5 -0.7 -0.5
Pain type(s) experienced in last month: Hip pain 0.6 0.7 1.2 -1.1 0.6
Supplements: Fish oil (including cod liver oil) 0.4 0.6 1.1 1.0 -0.3
High cholesterol (Self-reported) 0.3 0.6 1.1 -0.2 1.1
Medication: Bendroflumethiazide 1.6 2.5 3.7 -1.1 -1.9
Medication: Paracetamol 0.5 0.7 1.2 -1.1 -0.5
Medication: Lisinopril 1.3 1.7 3.2 -0.4 -1.8
Medication: Atorvastatin 3.6 4.4 8.0 2.8 0.9
Illnesses of father: High blood pressure 0.2 0.3 0.5 0.3 -0.7
Alcohol drinker status: Never 0.2 0.2 0.3 0.6 -0.3
Ever smoked 0.5 0.9 1.7 -0.4 -1.3
Basal metabolic rate 0.8 4.6 9.1 -0.1 3.0
Leg fat percentage (left) 0.9 3.1 3.9 1.5 -2.0
Arm fat-free mass (left) 1.3 6.8 13.5 -0.2 3.7
Number of operations (self-reported) 0.7 1.0 1.6 -0.6 1.3
Average weekly beer plus cider intake 2.7 3.9 6.9 -0.9 -2.6
Irritability 0.2 0.3 0.4 0.6 -0.6
Risk taking 0.1 0.2 0.3 -0.1 -0.6
Ever had prostate specific antigen (PSA) test 0.2 0.3 0.4 0.6 -0.4
Fractured/broken bones in last 5 years 0.2 0.3 0.4 -0.6 -0.5
Age started oral contraceptive pill 0.4 0.5 0.5 -0.7 -0.7
Diastolic blood pressure, automated reading 0.4 1.2 2.1 0.5 -1.4
Ever depressed for a whole week 0.0 0.0 0.1 -0.0 0.3
Unable to work because of sickness or disability 0.0 0.0 0.0 -0.2 -0.1
Commuting to job workplace: Cycle 0.6 0.7 1.3 1.2 -0.3
Myopia 0.1 0.1 0.2 -0.1 0.4
Vascular/heart problems diagnosed by doctor 1.1 2.9 5.7 -0.4 2.4
Cholesterol lowering medication 0.1 0.1 0.2 0.5 0.1
Medication: Omeprazole (e.g. Zanprol) 1.5 1.9 3.6 -1.9 -0.4
Pain experienced in last month 1.8 3.1 5.9 2.4 0.6
Supplements: Calcium 0.2 0.3 0.5 -0.7 0.2
Basal cell carcinoma (self-reported) 0.8 1.0 1.5 0.7 1.2
Heart attack/myocardial infarction (self-reported) 0.8 1.0 2.0 1.4 -0.0
Deep venous thrombosis (DVT) (self-reported) 1.5 2.0 3.5 -0.7 1.9
Heart disease (siblings) 0.9 1.1 2.0 -0.4 -1.4
Alcohol drinker status: Previous 1.4 1.6 3.1 1.8 0.0
Pack years of smoking 0.2 0.3 0.5 -0.7 0.3
Impedance of whole body 2.0 10.3 20.0 -0.8 -4.5
Leg fat mass (left) 0.2 0.7 1.0 1.0 -0.6
Arm predicted mass (left) 1.2 6.2 12.3 0.1 3.5