TWAS hub - SMYD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.117	0.0400	2.9e-04	0.020	0.017	0.017	0.011	0.010	1.4e-03	3.3e-03	2.8e-03	1.5e-02	2.1e-02
2	GTEx	Adipose Visceral Omentum	0.138	0.0510	4.1e-03	0.070	NA	0.072	NA	0.088	1.7e-04	NA	1.4e-04	NA	2.7e-05
3	GTEx	Artery Aorta	0.153	0.0540	2.1e-03	0.102	NA	0.040	NA	0.035	2.9e-06	NA	2.9e-03	NA	5.0e-03
4	GTEx	Cells Transformed fibroblasts	0.111	0.0450	8.1e-03	0.035	NA	0.066	NA	0.063	1.1e-03	NA	1.0e-05	NA	1.7e-05
5	GTEx	Nerve Tibial	0.239	0.0697	6.6e-04	0.110	NA	0.083	NA	0.094	3.3e-08	NA	1.8e-06	NA	3.8e-07
6	GTEx	Pituitary	0.390	0.1320	8.8e-03	-0.001	NA	-0.011	NA	0.012	3.5e-01	NA	8.4e-01	NA	1.6e-01
7	GTEx	Testis	0.246	0.0870	4.3e-03	0.032	NA	0.136	NA	0.087	1.4e-02	NA	1.3e-06	NA	1.1e-04
8	GTEx	Thyroid	0.218	0.0530	4.2e-06	0.042	NA	0.113	NA	0.061	3.3e-04	NA	6.2e-09	NA	2.0e-05
9	YFS	Blood	0.122	0.0228	0.0e+00	0.088	0.083	0.098	0.099	0.097	2.4e-27	1.2e-25	2.1e-30	1.5e-30	5.5e-30
10	TCGA	Thyroid Carcinoma	0.057	0.0250	5.6e-05	0.022	0.038	0.044	NA	0.037	3.1e-03	1.3e-04	4.1e-05	NA	1.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Irritability	3.5	6.0	14.5	1.7	3.2	2.8	2.6	1.7	-0.4	-0.4	0.5	-3.8	3.7
Diabetes (self-reported)	3.3	5.1	26.5	0.9	0.1	-1.4	0.4	-0.3	5.2	3.0	3.1	-1.6	0.9
Diabetes diagnosed by doctor	3.3	5.5	29.1	1.4	0.2	-1.3	0.4	-0.1	5.4	2.5	3.5	-1.4	1.0
Type 2 Diabetes (T2D) (2018)	3.2	6.0	35.2	0.7	-0.9	-2.5	-0.4	-0.8	5.9	2.2	3.2	-1.0	0.4
Cholesterol lowering medication	3.1	4.6	10.2	-1.3	2.1	1.4	3.2	3.0	3.0	0.9	1.3	1.6	2.1
Neuroticism (2016)	2.9	4.2	11.6	-1.5	2.8	1.4	3.4	2.4	-1.5	-0.2	0.4	-1.9	2.6
Pulse wave Arterial Stiffness index	2.5	2.9	5.5	-0.3	2.2	2.1	1.8	1.6	2.4	-0.7	1.8	-0.7	2.1
Pulse wave peak to peak time	2.4	2.8	5.9	0.2	-2.2	-2.0	-1.9	-1.7	-2.4	0.8	-1.6	0.8	-1.8
Diabetes (father)	2.3	2.8	8.7	0.9	-2.3	-2.9	-1.1	-1.6	3.0	-0.2	0.2	0.6	-0.7
Noisy workplace	2.2	2.7	7.1	2.0	1.6	1.9	0.3	0.7	2.4	0.2	2.7	-1.5	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.1	3.2	11.4	-2.0	1.5	2.3	1.5	1.3	-3.4	-1.4	-1.1	-0.4	1.1
Type 2 Diabetes (T2D) (2012)	2.0	2.3	9.1	1.3	-0.9	-2.4	-0.8	-0.6	3.0	0.9	1.8	-0.0	-0.7
Tinnitus: Yes, but not now, but have in the past	2.0	2.2	6.5	0.9	1.6	2.5	1.7	1.7	0.5	1.0	0.0	0.4	2.1
Medication: Lansoprazole	2.0	2.3	6.8	-1.3	1.9	1.8	2.6	2.3	-0.8	-0.2	-0.7	0.2	1.2
Medication: Amlodipine	2.0	2.8	8.6	-0.5	2.1	0.9	2.9	2.6	-0.5	-0.6	-1.3	-2.0	0.9
Neuroticism score	1.9	3.9	8.1	-0.9	2.8	1.2	1.8	2.5	-2.0	-0.6	-0.0	-2.6	2.8
Angina	1.8	2.3	6.2	-1.6	2.2	1.1	2.5	2.3	0.0	0.1	0.3	0.4	1.6
Medication: Atenolol	1.8	2.3	7.5	-1.0	1.9	1.0	2.7	1.8	-0.1	0.7	-0.6	0.7	2.3
Mouth/teeth dental problems: Bleeding gums	1.8	2.3	5.5	0.1	2.3	-0.2	2.3	2.4	0.3	-0.1	-0.0	-1.3	2.2
Ever had prostate specific antigen (PSA) test	1.8	2.0	5.0	-0.3	-1.3	-1.9	-2.2	-0.8	-0.5	-1.1	-2.0	0.7	-1.9
Relative age voice broke	1.7	2.6	4.3	0.9	-2.1	-2.0	-2.0	-1.7	1.8	1.8	1.7	-0.3	-0.6
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	5.8	1.1	-1.0	2.0	-1.6	-1.1	1.9	0.5	0.7	2.4	0.2
Alcohol usually taken with meals	1.7	2.8	9.1	0.9	3.0	1.2	0.5	1.8	-1.5	-2.0	-0.9	-1.6	1.9
Mouth/teeth dental problems	1.7	2.6	6.6	-0.1	-2.6	-0.9	-1.8	-2.2	-1.3	-0.5	-0.9	1.2	-2.5
Illnesses of father: Heart disease	1.7	2.4	5.8	0.3	1.9	2.3	1.8	1.9	0.0	0.5	1.1	0.9	2.4
Friendships satisfaction	1.7	2.1	6.9	1.0	1.6	2.5	1.7	-0.0	0.9	0.1	0.2	0.3	2.6
Chronic bronchitis/emphysema (mother)	1.6	1.9	3.9	1.4	2.0	2.0	1.2	1.9	0.2	-1.5	-1.1	-0.1	0.2
Angina (self-reported)	1.6	2.0	5.6	-1.7	2.2	0.9	2.4	2.2	0.2	-0.1	0.1	0.3	1.3
Miserableness	1.6	2.8	5.5	-0.7	2.2	1.5	2.0	2.0	-2.3	-0.7	-1.0	-0.6	2.4
Average weekly fortified wine intake	1.5	1.7	4.5	-0.7	-1.1	1.1	0.3	-1.0	-2.0	-0.5	-2.0	2.1	0.7
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.5	10.3	-2.2	2.6	1.8	1.6	3.2	1.7	0.7	1.6	-0.9	-0.1
Had major operations	1.5	1.7	4.0	-1.1	1.1	1.9	1.7	0.5	1.0	-1.6	-2.0	-0.5	0.4
Hearing aid user	1.5	1.7	3.3	0.5	1.7	1.8	1.3	1.1	-1.5	-1.6	-1.4	-0.8	-0.2
Fasting Glucose	1.4	1.7	12.9	1.3	0.4	-0.4	1.3	0.3	3.6	-0.1	0.2	0.3	0.7
Medication: Metformin	1.4	1.9	11.1	-0.1	0.5	0.6	1.4	0.1	3.3	1.5	1.1	-0.8	1.1
Number of incorrect matches in round	1.4	2.3	8.2	-2.7	0.8	1.0	1.1	1.3	-1.8	0.1	2.9	-0.4	0.3
Prospective memory result	1.4	1.7	4.7	-1.6	-0.5	-0.5	-1.0	0.2	-1.6	-1.8	-2.2	-0.4	-1.5
Ever highly irritable/argumentative for 2 days	1.4	1.7	4.1	2.0	0.9	1.2	0.3	-0.3	1.8	0.5	0.6	-1.8	1.6
Birth weight	1.4	3.0	21.8	-0.3	0.4	1.4	-0.0	0.1	-4.7	0.8	-2.0	-0.7	-0.4
Average weekly champagne plus white wine intake	1.4	2.0	10.0	1.0	1.2	1.7	1.0	1.0	-3.2	-0.7	-1.3	0.6	0.6
High cholesterol (Self-reported)	1.4	2.5	6.2	-0.8	1.8	1.0	1.8	2.5	2.2	1.2	1.8	-0.3	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	4.2	-0.3	2.1	1.6	1.4	1.9	-1.9	-0.1	0.6	-0.5	0.5
Financial difficulties in last 2 years	1.3	1.8	6.3	0.7	0.8	2.5	-0.3	-0.1	-1.6	1.7	0.5	-0.3	2.2
Pulse wave reflection index	1.3	1.6	4.9	0.5	1.6	0.8	1.6	1.2	1.6	-1.0	0.6	-0.5	2.2
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	5.4	-1.0	0.7	2.3	1.8	0.8	-1.4	0.4	1.0	1.3	2.2
Back pain experienced in last month	1.3	1.9	4.8	-1.2	1.5	2.2	2.2	1.5	-0.3	-0.6	0.2	0.8	1.6
Smoking status: Current	1.3	2.0	7.3	0.7	-1.8	0.9	-1.6	-2.7	-0.8	1.0	0.9	1.7	-0.6
Pain type(s) experienced in last month: Hip pain	1.3	1.7	4.5	-0.2	2.1	1.7	1.2	1.8	-0.1	0.8	0.5	-0.7	1.7
Neuroticism (Nagel 2018)	1.2	2.9	5.3	-0.5	2.3	1.8	1.8	2.3	-2.2	-0.9	-0.3	-0.8	2.2
Blood Red Count	1.2	11.5	36.8	-1.8	3.9	3.3	4.0	4.4	-1.1	-1.1	-6.1	-0.0	3.2
Sensitivity / hurt feelings	1.2	2.1	5.3	-2.1	1.8	0.5	2.3	2.1	-1.1	-0.7	-0.5	-0.3	1.0
Heart attack	1.2	1.6	6.5	-2.6	0.2	-1.2	1.1	1.2	1.5	1.1	-1.2	0.6	0.1
Medication: Simvastatin	1.2	1.8	3.9	-0.9	1.6	0.7	1.8	2.0	1.7	1.6	0.2	0.4	1.3
Length of working week for main job	1.2	1.3	9.2	-0.3	-0.2	-0.5	-1.1	-0.9	0.1	-3.0	0.7	0.5	1.0
Hair/balding pattern: Pattern 4	1.2	2.8	9.8	-0.2	-2.2	-1.1	-1.2	-2.9	3.1	0.1	-0.9	1.2	-0.9
Birth weight of first child	1.2	2.2	6.4	-1.5	-1.1	-1.5	-1.5	-0.5	1.2	2.3	2.5	-0.3	-0.5
Supplements: Vitamin C	1.2	1.4	3.1	-1.2	-1.5	-1.6	-0.9	-1.8	0.6	-0.6	0.0	-0.4	-1.8
Illnesses of siblings: Diabetes	1.2	1.5	4.2	-0.7	1.0	0.5	1.7	1.3	2.0	1.2	1.6	0.3	0.6
Handedness (chirality/laterality): Left-handed	1.2	1.5	11.1	-1.0	-0.8	-0.7	-0.3	-0.4	-3.3	-0.2	-0.6	0.6	-0.9
Average weekly beer plus cider intake	1.2	1.8	5.2	-1.2	-0.4	2.3	1.5	-0.3	-1.2	1.2	1.4	1.7	-0.7
Verbal and Numeric Reasoning (VNR)	1.1	2.6	6.5	1.1	1.9	2.5	1.7	1.0	2.2	1.1	1.4	-0.1	1.9
Ovarian Cancer	1.1	1.4	3.9	-1.9	-0.8	0.3	-0.5	-0.5	-0.3	0.3	-1.8	2.0	-1.3
Bipolar Disorder (2011)	1.1	1.0	3.2	-1.4	-0.8	0.0	0.0	-0.3	-0.8	1.2	-1.8	1.3	-0.8
Neuroticism	1.1	2.7	5.0	-2.1	2.0	0.7	0.8	2.2	-2.0	-0.2	0.0	-1.9	2.2
Supplements: Zinc	1.1	1.2	3.4	-0.4	-0.7	-1.1	-0.3	-1.4	0.7	-1.2	1.8	-1.7	0.3
Pack years adult smoking proportion	1.1	1.7	5.4	-0.1	1.4	2.3	2.3	0.9	-0.2	-0.6	-0.1	-0.1	1.6
Current tobacco smoking	1.1	1.8	6.2	1.1	-1.5	1.0	-1.5	-2.5	-0.6	1.2	1.3	1.4	-0.1
Supplements: Glucosamine	1.1	1.4	6.8	1.5	-0.3	0.2	-1.2	-1.4	-0.4	-0.1	2.6	-0.4	-1.1
Illnesses of siblings	1.1	1.6	4.6	0.3	-1.3	-2.1	-2.1	-1.2	-0.4	0.3	1.2	-0.5	-1.1
Time employed in main current job	1.1	1.3	4.2	0.6	1.9	0.9	2.0	1.3	-0.2	0.7	-0.6	0.1	1.1
Depression (self-reported)	1.1	1.3	3.7	-1.9	0.8	0.3	1.2	1.6	-1.2	-0.8	-0.8	1.3	-0.6
Tense / ‘highly strung’	1.1	1.8	4.6	0.8	1.0	-0.2	0.7	0.4	-1.3	-2.0	-1.0	-2.2	2.0
Suffer from ‘nerves’	1.1	1.8	4.6	-1.4	1.3	0.3	0.9	1.9	-1.4	-2.1	-0.1	-1.7	0.5
Medication for cholesterol	1.1	1.7	3.6	1.0	-1.3	-0.9	-1.9	-1.9	-1.3	-0.8	-0.7	-1.3	-1.3
Medication: Aspirin	1.1	1.4	4.7	-1.4	0.4	0.0	1.1	1.1	1.1	2.2	0.4	1.6	1.0
Medication: Gliclazide	1.1	1.3	4.5	1.4	0.7	-1.4	0.8	0.3	1.5	0.7	0.4	-2.1	0.2
Commuting to job workplace: Cycle	1.1	1.4	5.3	-1.4	-0.0	-1.4	-1.0	-0.2	0.3	-0.7	-1.5	-1.0	-2.3
Basal cell carcinoma (self-reported)	1.1	1.3	2.7	1.5	-1.5	-0.7	-1.0	-1.6	1.6	0.1	0.4	1.2	0.3
Heart attack/myocardial infarction (self-reported)	1.1	1.4	5.7	-2.4	0.3	-1.1	1.1	1.2	1.4	1.1	-1.0	0.4	0.2
Hypothyroidism (self reported)	1.0	2.3	8.7	-0.9	0.9	-0.2	1.9	1.1	0.7	2.1	3.0	-0.6	1.7
Chronotype (morning person)	1.0	2.3	9.4	-1.4	0.2	-0.3	-0.1	0.6	0.9	-3.1	-3.1	0.3	-1.1
Average weekly spirits intake	1.0	1.2	5.2	-1.0	-0.5	0.4	0.3	0.4	-0.2	1.1	0.6	1.9	-2.3
Ever had hysterectomy (womb removed)	1.0	1.1	4.5	-1.3	0.4	0.6	1.2	0.9	-0.2	0.7	0.9	2.1	0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	5.6	-1.3	2.3	2.4	1.7	2.2	1.2	0.1	0.6	-0.7	0.5
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.7	-1.8	-0.8	0.7	-0.4	-0.3	-0.9	-0.9	-2.2	1.1	-0.5
Hair/balding pattern: Pattern 3	1.0	1.5	6.1	-0.4	-1.2	0.0	-0.6	-0.8	2.5	1.7	1.5	0.1	0.9
Number of live births	1.0	1.4	3.3	1.7	-1.3	-1.8	-1.3	-1.5	-0.3	-0.1	0.3	-1.0	-0.8
Loud music exposure frequency	1.0	1.0	2.6	-0.2	0.6	0.8	-0.0	0.3	1.5	1.5	1.6	-0.9	1.2
Shortness of breath walking on level ground	1.0	1.2	3.9	-2.0	0.7	-1.2	0.6	0.9	-0.3	-0.6	-0.1	-2.0	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	4.0	-0.5	1.0	1.5	0.9	-0.2	-2.0	-0.8	-0.7	-0.6	1.5
Alcohol intake frequency.	1.0	2.2	4.2	1.1	1.5	1.4	1.9	1.7	2.0	1.1	0.5	1.2	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	2.9	-1.4	1.1	1.3	1.0	1.7	-0.2	0.4	0.4	1.4	0.2
Alcohol drinker status: Previous	1.0	1.2	2.2	0.4	1.0	1.5	1.2	1.1	-0.5	1.3	-0.6	1.3	1.4
Breast Cancer	0.9	2.2	7.6	0.3	-1.8	0.2	-1.0	-2.0	2.8	-0.1	-1.3	1.9	0.2
HbA1C	0.9	1.0	2.5	1.3	0.8	-0.5	0.7	1.4	1.0	1.3	1.6	-0.2	-0.3
LDL Cholesterol	0.9	1.4	6.2	0.5	0.8	1.3	1.0	0.8	2.5	1.4	1.3	0.0	-0.4
Frequency of depressed mood in last 2 weeks	0.9	1.2	4.0	-0.1	0.6	1.7	-0.2	-0.0	-1.8	2.0	-0.1	0.7	1.1
Relative age of first facial hair	0.9	1.8	6.2	1.1	-0.9	-0.7	-0.9	-0.4	1.4	2.3	2.5	0.2	1.2
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.7	0.3	-0.1	0.2	0.2	-0.8	2.2	1.2	0.8	0.6	1.3
Vitamin and mineral supplements	0.9	1.2	3.4	0.1	0.5	1.1	0.7	1.3	-0.1	1.8	-0.2	1.6	1.5
Diabetes (mother)	0.9	1.2	9.0	0.5	0.1	-1.0	0.8	0.2	3.0	0.7	0.1	-0.2	0.1
Townsend deprivation index at recruitment	0.9	1.3	3.3	-1.6	0.8	1.0	0.8	1.8	0.6	1.8	1.1	0.5	0.1
Hayfever, allergic rhinitis or eczema	0.9	2.0	5.4	-1.7	1.5	0.0	0.4	2.0	-1.2	-0.2	1.6	-2.3	1.1
Multivitamins +/- minerals	0.9	1.2	2.4	-0.2	-1.0	-1.2	-1.5	-1.4	0.1	-1.6	0.4	-0.8	-1.5
Chronic bronchitis/emphysema (father)	0.9	1.0	3.1	0.8	-0.9	-1.8	-1.4	-0.8	0.4	-0.8	0.9	-0.7	-0.9
Forced vital capacity (FVC)	0.9	3.3	17.6	-1.7	-1.5	-1.1	-0.4	-1.1	-4.2	-1.9	-0.1	-2.1	-0.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	3.8	-2.0	1.2	-0.1	1.0	1.5	0.4	0.4	1.5	-1.0	0.5
Medication: Ramipril	0.9	1.1	3.3	0.9	-1.0	-0.9	-0.0	-1.1	1.8	-1.3	-1.5	0.5	0.2
Falls in the last year	0.9	1.2	5.1	-2.3	1.0	0.5	0.9	1.7	0.2	-0.1	-0.5	-1.1	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	3.1	-0.3	1.3	0.8	1.8	1.7	1.1	0.4	0.2	-0.1	0.8
High blood pressure (siblings)	0.9	1.3	4.2	-0.8	0.7	1.2	1.8	1.0	0.9	-0.5	-2.1	0.0	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	4.0	-2.0	0.8	1.6	-0.6	0.6	-0.9	-0.2	-1.4	0.9	-0.4
Eye problems/disorders: None of the above	0.9	1.0	4.5	-0.2	1.0	0.2	1.0	0.8	-2.1	-0.8	1.4	-0.7	-0.0
Medication for pain relief, constipation, heartburn	0.9	1.6	4.0	0.3	-0.5	-1.9	-1.1	-0.6	-0.1	-2.0	-1.2	-1.6	-1.4
Overall health rating	0.9	2.0	8.9	0.5	1.5	2.2	1.0	0.9	0.1	0.8	1.0	0.1	3.0
Commuting to job workplace: Car/motor vehicle	0.9	1.0	3.9	-0.3	-1.7	-0.8	-2.0	-0.8	-0.4	-0.4	-0.7	0.5	-1.0
Medication: Aspirin	0.9	1.2	3.9	-1.2	0.6	-0.0	1.2	1.2	0.8	2.0	0.6	1.0	1.1
Osteoarthritis (self-reported)	0.9	1.1	3.6	-0.2	-0.1	1.9	-0.6	-0.5	-1.6	-1.1	0.7	-0.4	-1.5
Medication: Blood pressure	0.9	1.7	3.0	0.5	1.0	1.1	1.7	1.7	1.7	0.4	0.4	1.5	1.6
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	6.1	-1.6	-0.2	0.5	0.3	0.0	-2.5	-0.5	-1.4	-0.1	-0.4
Heart disease (siblings)	0.9	1.2	5.0	0.5	1.2	2.2	0.9	0.8	-1.3	-0.3	-0.5	0.7	0.9
Bipolar Disorder (2018)	0.8	1.3	5.2	-1.1	-0.1	1.5	-0.1	-0.4	-2.3	-0.5	-1.8	0.9	-0.5
Depressed Affect (Nagel 2018)	0.8	1.8	4.9	-0.6	1.7	1.4	1.1	1.7	-2.2	-0.7	-0.2	-0.3	1.6
Worry (Nagel 2018)	0.8	1.8	4.7	-0.9	1.4	0.5	0.5	1.5	-1.3	-1.3	1.2	-2.2	1.7
Crohns Disease (2017)	0.8	1.9	4.7	0.7	1.4	1.1	1.5	0.3	-1.3	0.3	1.4	-2.0	2.2
Major Depression (MDD)	0.8	1.0	2.7	-1.7	-0.9	0.2	-0.2	-0.9	-1.2	0.0	-1.1	1.6	-0.5
Reaction Time	0.8	1.5	7.0	-0.8	-0.1	1.1	-0.3	0.1	0.9	2.2	2.6	-0.2	-0.2
Mean Putamen Volume	0.8	0.9	2.7	-1.7	0.4	-0.2	0.8	0.8	-0.8	0.8	1.6	0.1	1.0
Lupus	0.8	1.3	3.3	-0.1	0.9	1.3	0.7	0.9	-1.6	0.6	-1.8	1.6	0.2
Rheumatoid Arthritis	0.8	1.0	4.9	-0.7	-0.9	-2.2	-1.5	-0.7	0.3	0.3	0.5	-0.4	-0.9
Smoking Status	0.8	2.0	5.1	0.8	-1.2	1.6	-1.4	-2.2	-0.4	1.4	0.9	2.3	0.1
Allergy or Eczema	0.8	2.1	7.3	-0.9	1.5	0.3	0.4	2.0	0.1	0.0	2.7	-2.2	0.9
Respiratory disease	0.8	1.9	5.3	-0.6	-1.8	-0.8	-2.1	-1.7	-2.3	-0.9	-0.2	0.4	-0.7
Hearing difficulty/problems: Yes	0.8	1.2	3.5	0.3	1.1	1.1	1.3	0.3	0.2	-1.6	-1.9	-1.1	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	5.6	0.6	0.9	0.5	0.4	0.8	-2.4	0.9	0.8	0.8	1.6
Had other major operations	0.8	0.9	2.9	-0.5	-0.6	-1.0	-0.6	-1.2	1.7	-0.3	-0.6	-0.5	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	3.0	-1.7	0.9	-0.0	0.9	1.5	-1.3	-0.2	0.4	-1.2	1.7
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	13.9	-0.8	-0.8	-0.8	-0.3	-0.9	-3.7	-2.7	-0.9	-1.8	0.7
Blood clot in the leg (DVT)	0.8	1.0	4.3	-1.6	-0.3	0.7	0.4	-0.1	-2.1	-0.5	-1.5	0.1	-0.3
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	3.2	-1.1	0.9	-0.6	1.8	1.5	0.9	1.1	1.3	-1.7	0.4
Emphysema/chronic bronchitis	0.8	0.9	3.2	0.8	-1.8	-0.3	-1.2	-1.6	-0.2	-0.9	0.1	0.6	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	4.2	0.5	-1.8	-1.3	-2.0	-2.1	-1.3	-0.2	1.2	-0.5	0.3
Average weekly red wine intake	0.8	1.1	3.4	0.5	0.7	-1.2	0.5	0.1	-1.4	-1.8	-0.7	-0.9	-1.4
Loneliness, isolation	0.8	1.1	3.9	-0.6	1.0	0.3	1.3	0.6	-2.0	-1.1	-0.3	-0.5	1.5
Commuting to job workplace: Walk	0.8	0.8	1.7	0.8	1.1	0.2	1.1	0.9	1.3	0.4	0.5	-0.9	1.1
Illnesses of father: None of the above (group 1)	0.8	1.0	3.5	-1.3	1.1	0.3	-0.2	1.2	-0.8	0.3	-0.8	-1.9	-0.2
Wears glasses or contact lenses	0.8	1.0	5.8	-1.0	0.4	0.8	0.8	0.6	0.5	0.8	2.4	-0.0	0.3
Mother’s age at death	0.8	1.0	6.5	0.1	0.4	-0.4	0.2	0.6	-1.1	0.5	-2.5	0.9	-0.4
Eye problems/disorders: Glaucoma	0.8	1.0	3.5	-0.2	-1.2	-0.9	-1.9	-0.4	0.5	0.6	-1.0	1.1	-0.9
Ever depressed for a whole week	0.8	1.0	5.2	-1.6	0.4	1.0	-0.1	0.3	-0.5	-0.6	-2.3	0.0	0.4
Unable to work because of sickness or disability	0.8	1.0	5.6	-1.5	-0.7	0.6	-0.5	-0.1	-0.7	0.5	0.7	2.4	-0.4
Bipolar Disorder or Schizophrenia	0.7	1.6	6.6	0.4	1.0	2.6	0.5	0.5	-2.4	0.2	-1.5	0.2	0.6
Schizophrenia (2018)	0.7	1.4	5.3	1.5	1.3	2.3	0.7	1.0	-1.2	0.6	-0.5	-0.4	1.2
HDL Cholesterol	0.7	1.1	3.3	-1.5	-0.6	0.1	-1.0	-0.1	-1.8	-0.8	0.4	-1.1	-1.4
Primary Biliary Cirrhosis	0.7	1.0	3.4	-0.3	-0.5	0.7	-0.1	-0.4	-1.8	1.5	1.4	-0.2	-1.1
Lung FVC	0.7	3.6	13.0	-3.6	-0.8	-0.5	0.7	0.3	-3.1	-1.4	-0.8	-2.2	-2.0
Hand grip strength (left)	0.7	1.9	10.0	3.2	-1.3	-0.1	-0.8	-1.8	-1.5	-0.5	-0.6	-0.8	0.1
Medication for hormone replacement therapy	0.7	0.8	5.0	-2.2	0.7	-0.2	0.6	1.2	-0.7	0.6	-0.2	-0.4	-0.2
Medication: Co-codamol	0.7	0.8	1.8	-0.1	-1.1	-0.2	-0.2	-1.1	0.1	-1.1	-1.4	1.2	1.1
Severe depression (siblings)	0.7	0.8	5.0	0.5	0.6	-0.5	-0.7	0.3	-2.2	0.6	0.5	-0.9	-0.2
Trunk fat percentage	0.7	2.6	6.2	-1.1	2.4	1.0	1.7	1.5	2.5	1.2	0.6	-2.3	0.3
Taking other prescription medications	0.7	1.1	5.8	-2.4	0.5	-0.3	1.3	1.6	0.6	-0.1	0.1	0.4	-0.1
Stomach or abdominal pain in last month	0.7	0.9	3.4	-0.4	-1.4	0.9	-0.7	-1.8	-0.5	1.2	0.2	0.6	-0.0
Hair/balding pattern: Pattern 2	0.7	0.9	2.3	-0.0	0.3	-0.8	0.3	0.4	-1.2	-0.9	-1.1	-1.5	-1.5
Worrier / anxious feelings	0.7	1.4	4.7	-0.0	1.3	1.0	1.1	1.2	-1.0	0.7	0.9	-1.2	2.2
Happiness	0.7	0.8	2.8	1.7	1.0	1.1	0.4	0.3	0.6	0.7	1.1	-0.8	0.5
Mouth/teeth dental problems: Dentures	0.7	1.1	3.6	-0.7	1.5	0.5	0.6	1.6	1.9	0.1	0.5	-1.0	0.8
Illnesses of mother	0.7	0.9	2.7	-0.1	-0.9	-1.6	-1.0	-1.0	-0.7	-0.2	1.4	-1.0	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.4	11.5	-1.4	-1.4	-0.7	-0.7	-1.7	-3.4	-1.6	-0.9	-0.7	0.6
Peak expiratory flow (PEF)	0.7	1.5	8.2	0.4	-0.3	0.3	-0.2	-0.7	-0.8	-2.9	-1.3	-1.9	0.4
Glaucoma (self-reported)	0.7	0.9	4.7	-0.6	-0.4	-0.7	-1.1	0.3	2.2	0.4	-0.4	1.1	-0.5
Gout (self-reported)	0.7	1.0	2.3	-0.2	1.2	1.5	0.9	1.4	-1.1	-0.1	-1.4	-0.3	0.0
Forced vital capacity (FVC), Best measure	0.7	2.6	12.3	-2.1	-1.8	-1.1	-0.5	-1.6	-3.5	-0.9	-0.0	-1.2	-0.1
Health satisfaction	0.7	1.0	2.7	0.5	1.4	1.6	0.1	0.1	-0.8	-0.2	0.7	-1.1	1.4
Mouth/teeth dental problems: Loose teeth	0.7	0.9	3.7	1.0	0.6	-0.3	0.7	0.2	1.6	-0.4	-1.9	0.4	-0.1
Migraine (self-reported)	0.7	0.8	2.3	-0.3	-1.5	-0.4	-1.2	-1.2	0.9	-0.5	-0.4	-0.1	-1.2
Heart disease (mother)	0.7	0.9	3.0	-0.2	-1.1	0.3	-0.8	-1.1	1.2	0.9	0.0	1.7	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	3.6	0.1	-0.6	-1.1	0.1	-1.0	-0.8	-1.2	0.1	-1.9	0.1
Smoking status: Previous	0.7	1.1	3.1	1.1	1.6	1.8	0.6	0.9	1.4	-0.1	0.6	-0.0	1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.2	0.9	-0.6	-0.8	-0.7	-1.1	-0.3	-1.0	0.2	-1.5	-0.6
Qualifications: nursing, teaching	0.7	1.1	3.2	-1.0	1.2	-0.6	0.2	1.8	1.2	0.3	-1.7	0.0	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	5.3	-2.1	0.3	-0.7	0.9	0.7	-2.3	-0.6	-0.7	-1.4	0.1
Number of self-reported non-cancer illnesses	0.7	1.2	6.8	-0.9	0.7	2.6	0.4	0.7	-1.2	-0.0	-0.8	1.0	-0.3
Number of operations (self-reported)	0.7	1.1	3.7	0.5	-0.1	1.4	-0.1	-1.0	1.4	-0.6	-1.9	0.1	-1.3
Pack years of smoking	0.7	1.0	3.8	-0.3	1.0	1.9	1.8	0.7	0.0	-0.7	-0.5	0.2	0.7
Depression (Nagel 2018)	0.6	0.9	4.2	-0.2	1.2	0.6	0.4	1.2	-2.1	0.4	0.7	0.2	-0.0
Schizophrenia vs Biploar Disorder	0.6	0.8	4.6	-0.1	0.9	0.3	1.1	0.6	-0.1	0.7	2.1	-0.5	0.4
Crohns Disease (2012)	0.6	0.9	1.9	1.0	-0.9	-0.6	-0.7	-1.1	-1.1	1.4	1.4	-0.3	-0.2
Schizophrenia (2014)	0.6	1.4	5.4	0.9	1.3	2.3	1.0	1.0	-1.4	1.0	-0.0	-0.5	0.9
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.9	0.7	0.5	1.7	-0.7	-0.0	-0.2	0.7	0.8	-1.5	-0.4
Ever used hormone-replacement therapy (HRT)	0.6	0.7	2.5	-1.6	0.3	0.9	0.6	0.5	-0.8	-0.8	0.3	0.9	-1.1
Systolic blood pressure, automated reading	0.6	1.7	4.0	1.0	-1.4	-1.1	-1.1	-0.7	1.9	0.6	-0.3	1.9	-2.0
Fed-up feelings	0.6	1.0	2.7	0.6	1.3	0.9	0.7	0.7	-1.6	1.3	0.3	-0.8	1.3
Past tobacco smoking	0.6	1.0	3.6	-1.2	-0.9	-1.9	-0.2	-0.2	-1.7	-0.7	-0.8	-0.3	-0.4
Nervous feelings	0.6	1.1	2.8	-1.5	1.2	0.5	1.3	1.3	-0.5	-0.6	0.3	-1.7	0.7
Father’s age at death	0.6	0.8	4.4	-0.7	-0.1	-0.5	0.6	-0.1	1.2	2.1	0.8	0.3	-0.5
Medication: Ventolin 100micrograms inhaler	0.6	0.7	3.7	-1.9	-0.3	-0.5	0.0	-0.2	0.9	-1.2	0.5	-0.8	-0.2
Body fat percentage	0.6	2.3	6.4	-0.9	2.1	1.0	1.5	1.4	2.5	1.3	0.8	-1.9	-0.1
Exposure to tobacco smoke outside home	0.6	0.8	2.5	-1.1	-0.1	0.0	0.5	-0.2	1.6	0.4	1.2	1.2	1.1
Wheeze or whistling in the chest in last year	0.6	1.1	4.5	-1.1	0.4	1.4	-0.5	0.2	-0.8	1.4	2.1	0.3	0.4
Number of children fathered	0.6	0.6	3.1	0.4	1.7	0.1	0.6	1.3	0.0	0.1	0.2	-0.1	1.0
Qualifications: College or University degree	0.6	1.8	11.9	-0.9	-0.7	-0.9	-1.4	-0.5	0.2	-0.5	-3.5	0.7	-1.2
Medication: Allopurinol	0.6	0.8	2.2	-0.1	1.0	1.0	0.9	1.2	-1.1	0.5	-1.5	-0.2	0.5
Chest pain or discomfort	0.6	0.8	2.9	-0.5	0.5	1.1	0.0	0.3	-1.0	1.6	1.7	-0.5	0.2
Eye problems/disorders: Cataract	0.6	0.7	2.4	-0.1	-1.0	-0.2	-1.3	-0.5	0.5	0.0	-1.6	0.5	-1.0
Intelligence (Savage-Jansen 2018)	0.5	1.7	5.6	2.4	1.6	2.1	0.4	0.7	1.5	0.4	0.1	-0.9	0.6
Alzheimer’s Disease (in father)	0.5	0.6	2.0	-1.4	-0.1	-0.7	-0.0	0.5	-0.3	1.2	0.2	-1.2	0.3
Alzheimer’s Disease (including proxy)	0.5	0.8	5.2	-0.9	-0.2	0.2	-0.7	0.2	-2.3	-0.1	0.7	-0.7	0.3
Irritable Bowel Disease (IBD)	0.5	1.1	2.9	1.2	0.9	1.4	1.1	-0.1	-0.6	0.8	1.2	-1.7	0.7
Waist Hip Ratio (WHR)	0.5	2.2	5.5	1.3	-0.4	0.6	-0.7	-0.5	2.0	1.9	0.7	2.3	2.3
Number of treatments/medications taken	0.5	0.8	3.0	-0.8	1.1	0.4	1.7	1.5	-0.2	-0.4	0.1	1.0	0.1
Hand grip strength (right)	0.5	1.2	7.6	2.8	-0.4	0.1	-0.2	-1.2	-0.3	-0.4	-0.7	-1.5	-0.1
Maternal smoking around birth	0.5	0.8	2.6	0.6	1.0	1.6	0.0	0.5	0.8	-0.4	0.2	-1.1	1.2
Serious illness, injury or assault to yourself	0.5	0.6	3.2	0.2	0.9	0.1	0.4	1.1	0.5	-0.1	0.2	-0.1	1.8
Hearing difficulty/problems with background noise	0.5	0.8	2.9	-1.7	0.9	0.2	0.8	0.8	-1.2	-0.2	-0.7	-0.4	0.7
Allergy	0.5	1.2	4.0	1.8	-0.5	-0.2	0.4	-1.1	2.0	0.2	-0.9	1.3	-0.4
Fluid intelligence score	0.5	1.1	3.1	1.8	1.1	1.0	0.4	0.1	1.6	-0.0	0.6	-0.8	1.5
Arm fat percentage (right)	0.5	2.1	4.0	-1.2	2.0	1.0	1.6	1.4	1.9	1.5	1.0	-1.6	-0.5
Alcohol intake versus 10 years previously	0.5	0.7	1.7	-0.5	0.7	-0.2	0.5	1.0	1.3	-0.8	1.1	-0.6	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	3.3	0.3	0.5	0.6	-0.1	0.5	-0.7	0.1	1.8	-1.1	0.3
Medication: Cholesterol lowering	0.5	0.8	1.4	-1.0	1.0	-0.5	0.5	1.2	1.2	1.0	-0.3	-1.0	-0.5
Headache pain in last month	0.5	0.9	2.4	-0.3	0.5	1.1	0.4	0.4	-1.2	1.3	0.7	0.8	1.5
Worry too long after embarrassment	0.5	0.9	2.4	-0.2	1.5	1.0	1.2	1.3	-0.4	0.2	-0.3	0.2	1.2
Mean time to correctly identify matches	0.5	1.0	3.3	-1.5	-0.2	1.0	0.2	0.2	0.6	1.0	1.8	0.1	-1.3
Pulse rate, automated reading	0.5	1.5	3.3	1.0	1.8	0.9	0.7	1.6	-1.6	-1.5	-0.4	-1.3	0.6
Knee pain experienced in last month	0.5	0.8	2.7	-1.2	-0.9	-0.2	-1.2	-0.5	-1.6	0.0	-0.2	-0.1	-1.3
Arm fat percentage (left)	0.5	2.2	4.8	-1.0	2.2	1.3	1.8	1.3	2.1	1.3	0.9	-1.7	-0.1
Mood swings	0.5	0.9	2.0	0.4	1.2	1.3	0.7	0.6	-1.2	-1.0	-0.7	-0.6	1.4
Breast cancer (self-reported)	0.5	0.6	3.0	0.6	0.3	-0.9	-0.1	0.9	1.7	0.4	0.8	-0.1	0.7
Guilty feelings	0.5	0.8	3.7	-0.3	0.4	0.7	-0.1	0.1	-1.9	0.7	-1.3	0.6	1.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.0	-0.5	0.6	0.7	1.1	0.5	0.4	0.2	1.7	-0.5	0.3
Medication: Atorvastatin	0.5	0.6	1.8	0.5	1.2	-0.1	0.4	1.1	1.0	0.1	0.2	-1.4	0.1
Illnesses of father: High blood pressure	0.5	0.6	2.2	1.5	-0.5	0.4	0.6	-0.6	-0.5	0.4	0.2	1.2	-1.1
Age started oral contraceptive pill	0.5	0.7	3.2	-1.8	-0.2	-1.0	-0.7	0.6	-0.1	-0.1	0.7	-0.6	-1.1
Alzheimer’s Disease (in mother)	0.4	0.4	1.2	-0.6	0.5	0.5	-0.5	0.7	-1.1	-0.2	1.0	-0.3	0.6
Coronary Artery Disease (CAD)	0.4	0.5	1.2	0.6	1.1	0.9	0.8	0.7	-0.5	-0.5	-0.0	0.1	0.8
Triglycerides	0.4	0.7	4.9	2.2	-0.0	0.1	0.5	-0.4	0.9	0.1	-0.4	0.7	0.5
Blood White Count	0.4	3.3	18.2	-0.3	0.1	1.4	1.4	-0.6	-0.6	-1.9	-4.3	0.1	2.5
Qualifications: CSEs or equivalent	0.4	0.6	2.9	0.1	0.2	1.2	0.5	0.2	-1.7	-1.0	0.1	0.2	-0.2
Medication: Levothyroxine sodium	0.4	0.6	1.2	-1.1	0.6	-0.3	1.0	0.9	0.4	0.8	0.9	-1.1	-0.3
Trunk fat mass	0.4	1.7	3.4	-0.7	1.8	1.0	1.2	1.2	1.8	1.6	0.8	-1.7	0.0
Waist circumference	0.4	1.5	4.8	0.7	1.5	1.7	0.9	0.6	2.2	1.3	1.0	-0.3	0.8
Asthma	0.4	0.7	5.3	-1.1	-0.5	0.1	-0.2	-0.4	-2.3	0.2	0.7	0.0	0.0
Lung cancer (father)	0.4	0.4	1.1	-0.5	-0.3	-0.9	-1.0	0.8	-0.4	0.2	0.9	0.2	-0.6
Exposure to tobacco smoke at home	0.4	0.5	1.1	0.4	-0.9	-1.0	-1.0	-0.5	0.5	0.2	-0.9	0.4	-0.5
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.8	1.0	0.6	0.4	1.2	-0.2	0.5	-0.2	-0.4	-1.4	1.1
Medication: Paracetamol	0.4	0.6	3.0	-0.2	-0.7	0.3	-0.5	-0.3	-0.1	1.7	1.0	0.6	0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	1.5	-0.1	-1.2	-0.0	-1.0	-0.8	-0.7	-0.4	0.7	1.2	0.0
Leg fat percentage (right)	0.4	1.3	5.9	0.3	1.0	1.1	0.4	0.6	2.4	1.2	1.2	-0.7	-0.7
Number of full brothers	0.4	0.5	1.5	-0.2	-0.4	0.3	-1.2	-0.5	0.6	1.2	0.1	0.8	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.9	-0.4	0.3	0.3	-0.2	0.9	-1.0	-1.4	-0.9	-0.1	-0.1
Medication: Ibuprofen	0.4	0.5	2.1	1.5	0.4	0.8	-0.1	-0.3	0.0	-0.9	0.9	-0.8	0.0
Medication: Omeprazole	0.4	0.5	2.3	0.5	-1.1	0.5	-0.0	-1.5	0.9	-0.2	-0.4	0.4	-0.4
Medication: Seretide 50 evohaler	0.4	0.5	2.1	-0.2	-0.8	0.1	-0.5	-0.5	0.3	0.3	1.4	0.7	0.9
Whole body fat mass	0.4	1.6	3.4	-0.7	1.8	1.4	1.3	1.2	1.6	1.4	0.7	-1.5	0.0
Leg pain on walking	0.4	0.5	1.4	-0.0	0.1	-0.6	-1.1	0.2	1.2	-0.4	-0.8	-0.5	-1.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.3	1.1	0.3	0.5	0.8	-0.3	0.3	-0.4	-0.6	-0.8	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.7	-1.3	0.4	0.2	0.3	0.5	-0.5	-0.5	-1.1	0.2	-0.9
Asthma (self-reported)	0.4	0.8	4.0	-1.0	-0.8	-0.1	-0.4	-0.7	-2.0	0.4	0.9	0.4	0.0
Ever taken oral contraceptive pill	0.4	0.4	1.8	1.4	-0.1	-0.2	-0.8	0.1	0.6	0.8	-0.4	-0.1	0.6
Financial situation satisfaction	0.4	0.5	1.6	0.2	-0.0	-0.2	-1.1	-0.3	-1.3	0.0	0.7	-1.3	-0.4
Commuting to job workplace: Public transport	0.4	0.5	1.9	-0.4	-0.6	-0.9	-0.4	-0.3	-1.4	0.8	-0.7	-0.3	-0.4
Medication: Bendroflumethiazide	0.4	0.7	2.5	0.1	0.4	1.1	1.6	0.7	0.5	1.3	-0.0	0.6	0.2
Alcohol drinker status: Never	0.4	0.5	2.4	0.4	-0.5	-0.8	0.5	-0.1	0.6	1.1	-0.2	1.5	0.1
Leg fat percentage (left)	0.4	1.5	7.5	0.3	1.2	1.3	0.6	0.8	2.7	1.2	0.9	-0.8	-0.6
Fractured/broken bones in last 5 years	0.4	0.6	4.0	0.3	0.1	0.5	0.1	-0.3	2.0	0.3	0.3	0.4	1.0
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.4	0.7	-1.0	-0.5	-1.9	-1.3	-1.7	0.0	0.3	-0.6	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.4	0.5	-0.5	1.1	0.5	-0.9	0.7	0.1	0.0	1.2	0.1
Pain experienced in last month	0.4	0.7	1.9	0.1	-0.2	-1.4	-0.1	0.0	1.2	-1.3	-1.2	-0.4	0.6
Supplements: Calcium	0.4	0.4	1.8	-0.9	0.4	0.4	1.4	0.1	0.3	-0.1	0.7	0.5	0.8
Prostate Cancer	0.3	0.4	1.4	0.4	-0.4	-1.2	0.3	-0.7	-0.3	-0.2	-0.6	-1.2	0.1
Age at First Birth	0.3	0.5	1.4	1.2	0.7	0.7	-0.9	0.5	-0.1	-0.3	-0.5	-0.7	0.8
Ulcerative Colitis	0.3	0.5	1.8	0.0	-0.4	0.3	-0.2	-0.6	0.2	1.4	0.6	-0.4	-1.3
Blood Eosinophil Count	0.3	2.5	5.2	1.8	-2.0	0.5	-2.3	-2.1	1.4	0.6	-0.8	2.0	-1.1
Heel T-Score	0.3	2.4	16.2	0.4	1.0	0.8	1.1	1.1	4.0	0.8	-0.5	-0.9	1.3
Systolic Blood Pressure	0.3	1.3	4.6	1.9	-1.2	-1.1	0.4	-0.8	1.3	-0.3	-0.4	2.1	0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	2.3	0.0	0.0	0.8	0.5	0.6	0.2	-0.0	-0.1	1.5	0.2
High blood pressure	0.3	0.8	3.0	0.0	1.0	0.5	1.7	1.0	1.3	-0.3	-0.1	0.1	0.9
Sitting height	0.3	1.9	8.4	-0.4	-1.5	0.7	-1.1	-1.2	-2.9	1.6	-1.0	1.1	0.2
High blood pressure (mother)	0.3	0.4	1.0	0.3	0.7	0.2	0.9	1.0	0.7	0.5	-0.4	-0.2	0.8
Body mass index (BMI)	0.3	1.4	3.4	0.1	1.9	1.9	1.2	1.2	1.3	1.2	0.8	-0.7	-0.0
Had menopause	0.3	0.4	1.7	-0.2	0.3	0.9	1.3	0.6	0.1	0.1	0.0	0.8	0.1
Impedance of arm (right)	0.3	1.2	6.4	-2.5	-0.2	-1.6	0.6	0.3	0.6	-0.5	0.5	-1.4	0.0
Pulse rate	0.3	0.6	2.5	0.8	-0.8	-0.5	-1.6	-1.0	-0.2	0.1	0.5	-0.0	-0.7
Impedance of arm (left)	0.3	1.5	4.1	-2.0	0.7	-0.7	1.5	0.4	1.5	-0.8	0.5	-1.7	1.2
Arm fat mass (right)	0.3	1.4	3.1	-0.5	1.8	1.5	1.3	1.1	1.0	1.6	0.7	-0.9	0.0
Breastfed as a baby	0.3	0.3	1.0	0.3	-0.4	0.3	-0.5	-1.0	0.2	-0.9	-0.7	-0.1	-0.5
Comparative body size at age 10	0.3	0.7	2.0	-1.2	0.6	0.6	1.4	0.8	-1.0	0.2	-1.2	-0.1	-0.1
Age at first live birth	0.3	0.5	2.8	0.5	0.3	-0.0	0.3	-0.2	-0.8	-0.8	-0.9	-1.7	0.2
Leg fat mass (right)	0.3	1.0	2.4	-0.1	1.3	1.3	0.4	0.8	1.2	1.6	0.9	-0.9	-0.2
Comparative height size at age 10	0.3	1.9	3.6	-1.1	-1.8	-1.4	-0.6	-1.3	-1.9	-0.8	-1.9	1.6	0.1
Age at last live birth	0.3	0.4	2.3	0.4	-0.1	0.1	-1.0	0.0	-1.5	0.1	-0.2	0.0	-0.8
Family relationship satisfaction	0.3	0.3	1.8	0.1	0.8	0.1	0.5	0.3	-1.4	-0.5	-0.1	0.0	-0.2
Hypertension (Self-reported)	0.3	1.0	3.3	0.0	1.1	0.3	1.8	1.2	1.5	-0.0	0.1	0.5	1.1
Long-standing illness, disability or infirmity	0.3	0.5	1.4	-0.8	-0.7	0.8	-1.2	-0.9	0.2	0.1	-0.5	-0.2	-0.9
Ever had bowel cancer screening	0.3	0.4	2.1	-0.1	0.3	1.4	0.2	0.3	0.7	-0.9	-0.3	0.4	0.0
Mineral and other dietary supplements	0.3	0.4	1.7	0.2	-0.1	-0.4	0.2	0.7	0.7	0.6	-1.3	0.0	1.0
Osteoporosis (self-reported)	0.3	0.4	1.4	-0.5	0.8	0.2	1.2	0.2	0.9	-0.3	-0.4	0.3	0.8
Arm fat mass (left)	0.3	1.4	3.3	-0.3	1.8	1.6	1.3	1.1	1.2	1.4	0.8	-0.9	0.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.6	-0.7	-0.1	-0.4	0.1	-0.9	-0.1	-0.3	1.2	-0.2	-0.9
Medication: Lisinopril	0.3	0.4	0.9	-0.5	0.6	0.7	0.6	0.8	-0.3	0.7	0.2	0.9	-0.2
Ever smoked	0.3	0.6	2.0	1.4	0.3	1.3	-0.2	-0.7	1.1	0.6	-0.2	0.1	-0.2
Risk taking	0.3	0.4	1.5	0.6	0.0	-0.8	-0.4	0.6	0.5	-0.8	-0.1	1.2	-0.7
Myopia	0.3	0.4	2.5	-0.3	0.9	0.3	-0.0	0.6	-0.3	-0.4	0.1	-1.6	0.1
Leg fat mass (left)	0.3	1.2	2.4	-0.0	1.4	1.6	0.6	1.0	1.5	1.5	0.8	-0.8	-0.1
Ulcerative Colitis (UC)	0.2	0.5	1.1	0.6	0.3	1.0	0.6	-0.0	0.3	1.0	0.2	-0.7	-1.1
Blood Platelet Count	0.2	2.9	7.6	2.7	-1.9	-1.5	-1.4	-2.8	1.1	-2.0	-1.1	-0.4	0.3
Lung FEV1/FVC ratio	0.2	1.2	3.5	1.2	1.4	0.8	0.8	0.3	1.1	-0.4	-1.9	0.4	1.4
Hair Pigment	0.2	4.5	8.9	-0.6	2.3	1.1	2.3	2.7	-3.0	2.2	-2.2	2.3	1.4
Impedance of leg (right)	0.2	0.9	3.9	0.5	-0.9	-1.3	-0.8	-0.6	2.0	-0.4	0.8	0.3	0.6
Age when periods started (menarche)	0.2	0.6	2.0	-0.9	-0.3	0.3	-0.4	0.3	-1.4	0.4	-0.9	0.9	0.9
Impedance of leg (left)	0.2	0.9	5.2	0.6	-0.8	-1.1	-0.7	-0.4	2.3	-0.7	0.2	0.0	0.6
Leg predicted mass (left)	0.2	0.8	2.7	0.1	0.7	1.5	0.1	0.0	-1.6	1.4	0.4	-0.5	0.5
Qualifications: None of the above	0.2	0.3	0.9	-0.9	-0.6	-0.6	-0.5	-0.2	-0.0	0.2	0.8	-0.2	-0.9
Pain all over the body in last month	0.2	0.3	1.1	-1.1	0.1	0.5	0.6	-0.1	-0.3	0.5	-0.2	0.2	-0.5
Weight	0.2	0.8	2.3	0.1	1.3	1.4	0.7	0.9	0.4	1.5	0.8	-0.6	0.3
Trunk fat-free mass	0.2	1.0	3.9	0.6	-0.7	0.7	-0.7	-0.5	-2.0	1.5	0.5	1.2	0.1
Hip circumference	0.2	0.8	1.8	0.3	1.2	1.3	0.7	0.5	0.7	1.2	0.6	-1.1	0.3
Trunk predicted mass	0.2	1.0	3.9	0.6	-0.6	0.8	-0.7	-0.5	-2.0	1.4	0.5	1.3	0.1
Arm fat-free mass (right)	0.2	0.8	2.0	1.4	-0.2	1.1	-0.6	-0.6	-1.1	1.3	0.3	0.6	0.6
Neck or shoulder pain in last month	0.2	0.2	1.3	0.1	0.1	1.2	0.4	0.0	0.1	0.2	-0.2	0.2	-0.9
Medication: Blood pressure	0.2	0.3	0.9	0.6	0.6	-0.6	0.8	0.1	0.4	0.1	-0.5	-0.9	-0.2
Medication: Paracetamol	0.2	0.2	1.2	-0.0	-0.5	0.2	-0.2	-0.3	-0.4	0.5	1.1	0.4	0.5
Diastolic blood pressure, automated reading	0.2	0.7	1.9	1.4	-0.8	-0.2	-1.1	-0.9	-0.3	0.3	-1.0	1.4	-0.3
Impedance of whole body	0.2	0.9	4.6	-0.7	0.2	-0.8	0.5	0.1	2.1	-0.6	0.4	-1.1	1.0
Body Mass Index (BMI) (2010)	0.1	0.2	0.7	-0.3	0.4	-0.2	0.2	0.6	-0.8	-0.2	0.4	0.1	-0.3
BMI	0.1	0.6	3.0	-0.7	0.3	0.8	-1.0	-0.0	0.5	1.7	0.2	-0.0	-0.7
Height	0.1	2.7	9.5	0.1	0.9	1.4	0.7	1.6	-2.2	1.9	-0.1	3.1	1.7
Cardiovascular Disease	0.1	0.5	2.8	-0.1	-0.5	-0.5	0.6	-0.2	1.7	0.1	0.2	0.1	1.0
Tanning	0.1	0.8	2.1	-1.5	0.6	0.3	1.1	0.9	1.2	-0.1	1.0	-0.3	-0.9
Leg fat-free mass (left)	0.1	0.8	2.3	0.0	0.6	1.5	0.1	-0.0	-1.5	1.5	0.5	-0.5	0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.0	0.0	0.7	-0.0	0.2	0.5	-0.1	-0.5	-0.2	-0.3	1.0
Standing height	0.1	0.9	3.4	0.2	-1.2	-0.7	-1.1	-0.9	-1.8	0.7	-0.1	0.4	0.9
Arm predicted mass (right)	0.1	0.8	1.8	1.4	-0.2	1.1	-0.7	-0.5	-1.3	1.2	0.2	0.7	0.4
Number of full sisters	0.1	0.2	0.4	-0.1	-0.6	-0.5	-0.6	-0.3	0.6	0.1	0.6	-0.2	-0.1
Whole body fat-free mass	0.1	0.8	3.5	0.5	-0.2	1.1	-0.5	-0.5	-1.9	1.4	0.4	0.6	0.1
Leg fat-free mass (right)	0.1	0.8	2.9	0.3	0.5	1.6	-0.0	-0.1	-1.7	1.1	0.1	-0.6	0.5
Whole body water mass	0.1	0.8	3.4	0.6	-0.2	1.0	-0.4	-0.4	-1.8	1.4	0.4	0.6	0.2
Leg predicted mass (right)	0.1	0.8	2.8	0.2	0.6	1.6	0.1	-0.0	-1.7	1.2	0.0	-0.6	0.5
Basal metabolic rate	0.1	0.6	2.1	0.5	0.2	1.3	-0.2	-0.1	-1.3	1.4	0.4	0.2	0.2
Arm fat-free mass (left)	0.1	0.7	2.1	1.2	-0.2	1.0	-0.6	-0.3	-1.2	1.5	0.2	0.9	0.2
Arm predicted mass (left)	0.1	0.7	1.8	1.3	-0.3	0.9	-0.6	-0.4	-1.3	1.3	0.2	0.9	0.1

Hub : Genes

SMYD2

Models

Trait associations