Hub : Genes

SNORA67

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Esophagus Mucosa 0.277 0.056 7.1e-08 0.184 NA 0.098 NA 0.158 2.3e-12 NA 4.6e-07 NA 9.7e-11
2 GTEx Liver 0.383 0.136 8.5e-03 -0.011 NA -0.009 NA -0.011 9.2e-01 NA 7.3e-01 NA 9.1e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 4.7 7.4 13.9 3.7 -1.0
Bipolar Disorder or Schizophrenia 0.6 1.5 2.7 1.6 -0.5
Depressed Affect (Nagel 2018) 0.2 0.4 0.7 0.4 -0.8
Depression (Nagel 2018) 0.0 0.0 0.0 0.1 0.2
Intelligence (Savage-Jansen 2018) 0.4 1.3 2.6 1.6 -0.2
Neuroticism (Nagel 2018) 0.3 0.6 0.9 1.0 -0.5
Schizophrenia (2018) 0.2 0.4 0.8 -0.9 0.1
Schizophrenia vs Biploar Disorder 2.2 2.9 4.1 -2.0 1.3
Worry (Nagel 2018) 0.1 0.1 0.2 0.4 0.2
Alzheimer’s Disease (in mother) 0.6 0.7 0.9 -1.0 0.7
Alzheimer’s Disease (in father) 0.1 0.1 0.1 0.4 0.2
Alzheimer’s Disease (including proxy) 0.3 0.4 0.8 -0.9 0.2
Crohns Disease (2017) 1.2 2.6 3.5 -1.3 -1.9
Irritable Bowel Disease (IBD) 1.5 3.6 7.2 -0.0 -2.7
Ulcerative Colitis (UC) 2.1 3.9 7.0 1.0 -2.6
Major Depression (MDD) 0.2 0.3 0.6 0.8 -0.1
Reaction Time 0.2 0.5 0.9 0.1 -1.0
Verbal and Numeric Reasoning (VNR) 0.3 0.8 1.6 1.3 -0.1
Breast Cancer 0.0 0.1 0.1 0.1 0.3
Ovarian Cancer 0.2 0.3 0.3 0.5 0.6
Prostate Cancer 1.7 2.4 4.1 -2.0 -0.8
Age at First Birth 1.1 1.6 1.9 1.4 1.1
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.4 0.5 0.9 0.9 -0.3
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 1.0 1.6 3.3 0.0 -1.8
Mean Putamen Volume 0.0 0.0 0.0 0.1 -0.1
Fasting Glucose 0.2 0.3 0.3 -0.5 0.5
HbA1C 0.5 0.5 1.0 0.2 -1.0
HDL Cholesterol 2.5 4.1 4.3 2.1 2.0
LDL Cholesterol 0.0 0.0 0.1 -0.2 0.2
Lupus 3.9 5.9 9.6 -3.1 -1.5
Neuroticism (2016) 0.4 0.6 1.1 -1.1 0.1
Primary Biliary Cirrhosis 1.0 1.4 2.7 -0.1 -1.6
Rheumatoid Arthritis 0.1 0.2 0.3 -0.1 -0.5
Schizophrenia (2014) 0.0 0.0 0.0 0.2 -0.2
Triglycerides 0.2 0.3 0.5 -0.7 0.2
Type 2 Diabetes (T2D) (2012) 0.7 0.9 1.2 1.1 -0.7
Ulcerative Colitis 1.9 2.7 4.0 1.2 -2.0
Blood Eosinophil Count 2.1 16.0 23.8 4.9 2.9
Blood Platelet Count 0.8 9.6 18.6 0.7 -4.3
Blood Red Count 0.2 1.6 2.5 1.6 0.8
Blood White Count 0.6 4.5 7.9 1.1 -2.8
Heel T-Score 3.5 27.5 42.1 6.5 3.6
BMI 0.4 2.1 3.9 -2.0 -0.5
Height 0.5 9.0 15.8 -4.0 1.5
Waist Hip Ratio (WHR) 0.9 4.0 7.3 -0.9 -2.7
Systolic Blood Pressure 1.6 8.0 10.4 -3.2 2.4
Smoking Status 1.2 2.8 5.1 0.6 2.3
Allergy or Eczema 0.6 1.4 1.8 -1.1 -1.3
Cardiovascular Disease 0.5 1.7 3.1 -1.8 0.6
Hypothyroidism (self reported) 0.2 0.4 0.9 -0.2 0.9
Respiratory disease 0.9 1.9 2.7 -1.6 -1.1
Type 2 Diabetes (T2D) (2018) 0.2 0.4 0.8 -0.9 -0.0
Lung FEV1/FVC ratio 1.5 7.5 15.1 3.9 -0.1
Lung FVC 0.5 2.7 5.3 2.3 0.2
Neuroticism 0.1 0.3 0.6 0.8 -0.1
Chronotype (morning person) 0.2 0.4 0.6 -0.8 -0.4
Hair Pigment 0.1 2.0 3.5 -0.7 -1.9
Tanning 0.1 0.6 1.1 0.3 1.1
Hand grip strength (left) 0.7 1.9 3.7 -0.3 1.9
Number of treatments/medications taken 1.1 1.9 3.2 -0.7 1.8
Average weekly spirits intake 1.1 1.3 2.3 0.5 1.5
Sensitivity / hurt feelings 2.1 3.7 7.2 2.7 0.4
Frequency of depressed mood in last 2 weeks 0.0 0.0 0.0 0.1 0.2
Hearing difficulty/problems: Yes 0.1 0.1 0.2 -0.5 -0.1
Relative age of first facial hair 0.4 0.7 1.4 1.2 -0.2
Other serious medical condition/disability diagnosed by doctor 0.1 0.2 0.2 -0.4 -0.4
Ever used hormone-replacement therapy (HRT) 0.6 0.8 1.4 -1.2 0.4
Ever had hysterectomy (womb removed) 0.4 0.4 0.5 -0.7 -0.6
Systolic blood pressure, automated reading 1.7 4.9 8.7 -2.9 1.1
Eye problems/disorders: Diabetes related eye disease 0.9 1.0 1.3 -1.2 0.8
Angina 0.6 0.8 1.5 1.2 -0.2
Medication for hormone replacement therapy 0.5 0.6 1.0 0.5 1.0
Vitamin and mineral supplements 0.1 0.1 0.1 -0.1 0.4
Supplements: Zinc 0.4 0.4 0.8 -0.1 0.9
Medication: Co-codamol 2.4 2.8 4.5 -1.0 -2.1
Medication: Metformin 0.5 0.6 0.9 -0.6 0.9
Diabetes (father) 0.1 0.1 0.2 0.5 -0.1
Diabetes (mother) 1.2 1.6 1.6 -1.3 -1.2
Severe depression (siblings) 0.3 0.4 0.8 -0.0 0.9
Pack years adult smoking proportion 2.0 3.0 5.2 0.9 -2.3
Impedance of leg (right) 0.1 0.4 0.6 -0.8 -0.5
Leg fat-free mass (left) 0.2 1.3 1.8 -1.3 0.9
Trunk fat percentage 0.5 2.0 3.7 -1.9 0.6
Hand grip strength (right) 1.5 4.0 7.0 1.0 2.6
Townsend deprivation index at recruitment 0.7 1.0 1.6 -1.3 -0.7
Current tobacco smoking 0.1 0.2 0.3 0.6 -0.1
Average weekly fortified wine intake 1.2 1.4 1.5 1.2 1.2
Maternal smoking around birth 2.5 3.5 6.7 -0.6 2.6
Fed-up feelings 0.1 0.1 0.2 -0.4 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.0 0.0 0.0 0.2 0.1
Relative age voice broke 1.5 2.3 2.4 1.6 1.5
Taking other prescription medications 0.1 0.2 0.4 -0.1 0.7
Age when periods started (menarche) 1.4 3.3 6.5 -2.6 -0.2
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 0.8 0.5 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 1.3 2.9 4.8 2.2 1.0
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.3 -0.6 -0.4
Qualifications: CSEs or equivalent 0.2 0.3 0.5 -0.3 0.7
Serious illness, injury or assault to yourself 0.7 0.9 1.7 0.2 -1.3
High blood pressure 1.9 5.2 9.2 -3.0 1.1
Hayfever, allergic rhinitis or eczema 0.7 1.5 1.6 -1.2 -1.3
Multivitamins +/- minerals 0.1 0.2 0.3 -0.6 -0.1
Stomach or abdominal pain in last month 0.8 1.0 1.1 1.0 1.1
Supplements: Glucosamine 0.5 0.6 0.7 -0.8 0.7
Diverticular disease/diverticulitis (self-reported) 2.0 2.3 3.2 1.8 1.2
Medication: Atenolol 1.0 1.2 2.1 -0.6 1.4
Medication: Levothyroxine sodium 0.0 0.0 0.0 -0.0 0.0
Sitting height 1.0 7.1 12.9 -3.6 1.2
Chronic bronchitis/emphysema (father) 1.9 2.3 3.2 -1.8 1.2
High blood pressure (mother) 0.9 1.3 2.5 -0.2 -1.6
Body mass index (BMI) 0.1 0.5 0.6 -0.7 0.8
Impedance of leg (left) 0.0 0.2 0.2 -0.5 -0.4
Leg predicted mass (left) 0.3 1.3 1.8 -1.3 0.9
Trunk fat mass 0.6 2.6 5.0 -2.2 0.5
Waist circumference 0.4 1.5 3.0 -1.7 -0.1
Number of incorrect matches in round 0.1 0.2 0.3 -0.2 0.5
Past tobacco smoking 1.3 2.4 3.2 -1.2 -1.8
Alcohol usually taken with meals 2.3 3.7 7.3 2.7 0.3
Nervous feelings 0.1 0.2 0.4 -0.3 -0.6
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.1 1.3 1.1 -1.0
Hearing difficulty/problems with background noise 0.1 0.1 0.2 0.4 0.1
Hair/balding pattern: Pattern 2 0.8 1.0 2.1 -1.4 -0.1
Had menopause 0.3 0.3 0.5 -0.7 0.4
Had other major operations 1.3 1.6 3.2 -0.3 1.8
Forced vital capacity (FVC) 0.2 0.9 1.8 1.3 0.0
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.9 4.1 2.0 1.3
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 0.9 0.9 -0.2
Qualifications: None of the above 1.3 2.7 3.3 -1.8 -1.4
Financial difficulties in last 2 years 0.3 0.4 0.6 0.8 -0.4
Mouth/teeth dental problems 1.3 1.9 3.7 -1.9 0.4
Heart attack 1.6 2.0 2.8 1.7 -1.1
Allergy 1.9 4.4 5.3 2.3 1.9
Pain all over the body in last month 0.1 0.1 0.2 -0.3 0.4
Diabetes (self-reported) 0.2 0.3 0.6 0.1 0.8
Hayfever/allergic rhinitis (self-reported) 0.3 0.5 0.6 -0.5 -0.8
Medication: Ramipril 0.2 0.3 0.6 0.8 0.2
Medication: Simvastatin 0.7 1.0 1.6 0.6 1.3
Fluid intelligence score 0.5 0.9 0.9 1.0 -1.0
Illnesses of siblings 1.1 1.5 2.5 1.6 0.8
Neuroticism score 0.2 0.5 1.0 1.0 -0.1
Weight 0.6 2.8 4.4 -2.1 1.1
Impedance of arm (right) 0.4 1.8 3.5 -1.9 -0.3
Arm fat percentage (right) 0.3 1.1 2.0 -1.4 0.5
Trunk fat-free mass 0.3 1.6 2.4 -1.6 0.8
Hip circumference 0.4 1.7 2.0 -1.4 1.2
Time employed in main current job 2.6 3.0 4.4 -1.3 -2.1
Alcohol intake versus 10 years previously 6.0 8.9 15.4 -1.6 -3.9
Father’s age at death 0.3 0.3 0.4 -0.7 -0.5
Worrier / anxious feelings 1.0 1.8 2.1 1.4 -1.3
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 0.3 0.2 0.5
Falls in the last year 2.1 2.9 4.0 1.3 2.0
Hair/balding pattern: Pattern 3 1.2 1.9 2.5 -1.6 -1.1
Number of live births 0.1 0.1 0.2 0.4 -0.3
Forced expiratory volume in 1-second (FEV1) 0.8 2.5 5.1 2.2 0.2
Pulse rate 0.0 0.0 0.0 -0.1 0.1
Happiness 0.3 0.4 0.4 -0.6 0.6
Noisy workplace 1.0 1.2 2.3 -0.3 -1.5
Qualifications: A levels/AS levels or equivalent 1.5 3.4 5.9 2.4 0.9
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.2 -0.3 -0.5
Mouth/teeth dental problems: Dentures 0.2 0.4 0.7 0.2 -0.8
Asthma 0.5 1.1 1.5 -1.2 -0.8
Medication: Ibuprofen (e.g. Nurofen) 0.8 1.0 1.3 -0.9 1.1
Medication: Cholesterol lowering 1.3 2.0 3.9 2.0 0.0
Depression (self-reported) 1.3 1.6 2.9 1.7 -0.4
Medication: Lansoprazole 1.7 2.0 2.2 1.3 1.5
Prospective memory result 1.8 2.2 3.5 -1.9 -1.0
Lung cancer (father) 1.4 1.7 3.1 -0.5 -1.8
Illnesses of mother 0.5 0.6 1.1 0.4 1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.1 3.8 1.9 0.6
Pulse wave Arterial Stiffness index 1.0 1.1 1.3 -1.1 1.0
Impedance of arm (left) 0.1 0.4 0.9 -0.9 -0.1
Arm fat mass (right) 0.6 2.3 3.8 -1.9 0.9
Trunk predicted mass 0.3 1.5 2.2 -1.5 0.9
Standing height 0.5 5.4 10.3 -3.2 0.7
Length of working week for main job 2.3 2.5 5.0 0.2 -2.2
Exposure to tobacco smoke at home 0.8 0.9 1.3 -1.1 -0.7
Breastfed as a baby 0.4 0.5 1.0 0.3 1.0
Tense / ‘highly strung’ 0.4 0.6 0.7 -0.8 -0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.0 0.0 0.0 0.2 0.2
Hair/balding pattern: Pattern 4 0.5 1.1 2.2 1.5 0.3
Birth weight of first child 0.9 1.7 3.1 -1.8 -0.6
Peak expiratory flow (PEF) 1.6 3.7 6.2 2.5 1.0
Pulse wave reflection index 0.6 0.7 1.1 0.6 1.0
Ever highly irritable/argumentative for 2 days 0.4 0.5 0.9 -0.0 1.0
Loud music exposure frequency 0.0 0.0 0.1 0.1 -0.3
Qualifications: O levels/GCSEs or equivalent 2.4 3.9 7.7 2.8 -0.2
Mouth/teeth dental problems: Bleeding gums 1.0 1.2 1.9 0.8 -1.4
Blood clot in the leg (DVT) 0.8 1.1 1.2 -1.0 -1.1
Medication: Paracetamol 0.2 0.4 0.7 -0.8 0.2
Headache pain in last month 0.2 0.4 0.5 0.7 0.4
Medication for cholesterol, blood pressure or diabetes 0.0 0.0 0.0 -0.1 0.1
Glaucoma (self-reported) 0.9 1.0 1.9 1.4 -0.3
Gout (self-reported) 0.1 0.1 0.2 -0.4 0.1
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 0.5 -0.1 0.7
Medication: Amlodipine 0.8 1.2 2.0 -1.4 0.6
Medication: Ventolin 100micrograms inhaler 0.0 0.0 0.0 -0.2 0.0
Birth weight 1.0 2.2 2.9 1.7 1.2
Chronic bronchitis/emphysema (mother) 0.9 1.0 1.3 -1.1 0.9
High blood pressure (siblings) 0.5 0.7 1.0 -1.0 -0.6
Forced vital capacity (FVC), Best measure 0.2 0.8 1.2 1.1 0.6
Body fat percentage 0.3 1.1 2.2 -1.5 0.4
Leg fat percentage (right) 0.1 0.4 0.8 -0.9 -0.1
Arm fat-free mass (right) 0.2 1.0 1.2 -1.1 0.9
Exposure to tobacco smoke outside home 0.8 1.1 2.1 -1.5 0.1
Comparative body size at age 10 0.5 1.4 2.3 1.5 -0.7
Number of full brothers 0.5 0.6 0.9 0.6 1.0
Worry too long after embarrassment 1.1 1.8 2.5 1.6 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 1.3 -0.1 1.1
Wheeze or whistling in the chest in last year 0.5 0.9 1.3 -1.1 -0.7
Number of children fathered 1.0 1.2 1.6 1.3 0.9
Reason for reducing amount of alcohol drunk: Health precaution 0.3 0.3 0.6 0.8 -0.2
Age at first live birth 0.5 0.8 1.6 0.1 1.3
Pulse wave peak to peak time 0.8 0.9 0.9 1.0 -0.9
Health satisfaction 0.2 0.2 0.2 0.5 -0.5
Shortness of breath walking on level ground 1.0 1.2 1.4 1.0 -1.2
Qualifications: College or University degree 0.4 1.1 2.1 1.4 0.5
Eye problems/disorders: None of the above 0.8 1.0 1.2 -1.1 -0.8
Mouth/teeth dental problems: Loose teeth 1.0 1.2 2.3 1.5 -0.2
Emphysema/chronic bronchitis 0.7 0.8 1.0 -1.0 0.8
Medication for pain relief, constipation, heartburn 1.8 3.1 3.3 1.7 -1.8
Neck or shoulder pain in last month 0.0 0.0 0.0 -0.1 0.2
Medication: Blood pressure 0.5 1.0 1.7 -1.3 0.5
Angina (self-reported) 1.1 1.5 2.9 1.7 -0.3
Migraine (self-reported) 0.4 0.5 0.6 0.8 0.7
Medication: Ibuprofen 1.2 1.5 1.5 -1.2 1.2
Medication: Allopurinol 1.5 1.9 3.3 -0.8 -1.8
Medication: Omeprazole 0.1 0.2 0.3 0.5 -0.2
Medication: Seretide 50 evohaler 1.0 1.2 2.3 -0.2 1.5
Mean time to correctly identify matches 0.3 0.5 0.9 -0.4 -0.9
Heart disease (mother) 0.1 0.1 0.1 0.3 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 0.5 0.7 -0.0
Whole body fat mass 0.5 1.9 3.2 -1.8 0.8
Leg fat mass (right) 0.3 1.1 1.8 -1.4 0.5
Arm predicted mass (right) 0.2 0.8 0.8 -0.9 0.9
Pulse rate, automated reading 0.5 1.7 2.9 0.7 -1.7
Alcohol intake frequency. 3.6 8.4 9.0 -3.0 -2.8
Comparative height size at age 10 0.3 1.4 2.4 -1.6 0.7
Number of full sisters 0.5 0.7 1.2 0.2 1.1
Suffer from ‘nerves’ 0.2 0.3 0.6 0.8 0.0
Overall health rating 2.3 4.9 9.6 -0.4 -3.1
Chest pain or discomfort 0.7 1.0 1.8 1.4 -0.3
Had major operations 1.9 2.2 3.5 -1.9 -1.0
Age at last live birth 0.5 0.8 1.2 0.6 1.1
Family relationship satisfaction 1.5 1.8 3.1 -1.8 0.7
Leg pain on walking 2.5 3.1 3.1 -1.7 -1.8
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 0.5 -0.7 0.3
Commuting to job workplace: Car/motor vehicle 0.7 0.8 1.0 1.0 0.7
Illness, injury, bereavement, stress in last 2 years 2.0 2.4 4.7 0.3 2.2
Medication: Aspirin 0.5 0.7 1.0 -0.6 1.0
Supplements: Vitamin C 0.3 0.3 0.6 0.8 0.2
Knee pain experienced in last month 1.0 1.6 2.2 -1.5 0.9
Hypertension (Self-reported) 1.5 4.3 7.8 -2.8 0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 0.9 0.7 0.9
Illnesses of father: Heart disease 1.3 1.8 3.0 0.8 1.7
Illnesses of siblings: Diabetes 0.3 0.4 0.7 0.2 -0.8
Smoking status: Previous 0.4 0.6 0.9 0.5 0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.5 0.9 -0.3 0.9
Whole body fat-free mass 0.3 1.5 1.9 -1.4 1.0
Leg fat-free mass (right) 0.2 1.3 1.4 -1.2 1.1
Arm fat percentage (left) 0.2 0.7 1.0 -1.0 0.6
Average weekly red wine intake 2.2 3.3 5.1 2.3 1.2
Handedness (chirality/laterality): Left-handed 0.3 0.4 0.4 0.7 -0.6
Mood swings 0.1 0.2 0.4 0.6 -0.0
Loneliness, isolation 0.1 0.2 0.3 0.5 -0.2
Long-standing illness, disability or infirmity 0.6 0.9 1.6 -1.3 0.4
Ever had bowel cancer screening 0.1 0.2 0.3 -0.6 -0.2
Diabetes diagnosed by doctor 0.1 0.1 0.1 -0.3 0.3
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 2.0 -1.4 0.7
Friendships satisfaction 0.3 0.4 0.6 0.8 -0.5
Qualifications: nursing, teaching 0.6 0.9 1.0 0.8 -1.0
Commuting to job workplace: Walk 1.9 2.1 4.0 0.4 -2.0
Eye problems/disorders: Cataract 2.0 2.3 4.4 2.1 -0.5
Mouth/teeth dental problems: Mouth ulcers 0.5 0.7 1.3 1.1 0.4
Medication for cholesterol 0.4 0.7 1.3 0.1 -1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 1.1 -0.9 -1.0
Back pain experienced in last month 0.1 0.1 0.3 0.2 0.5
Mineral and other dietary supplements 2.2 3.0 4.6 2.1 1.1
Breast cancer (self-reported) 0.1 0.2 0.2 0.5 -0.2
Asthma (self-reported) 0.9 1.8 2.2 -1.5 -1.2
Osteoporosis (self-reported) 0.0 0.1 0.1 0.0 0.3
Osteoarthritis (self-reported) 3.9 5.1 9.0 -3.0 -1.1
Medication: Aspirin 0.3 0.4 0.4 -0.6 0.6
Medication: Gliclazide 3.2 3.7 6.0 -2.5 1.1
Illnesses of father: None of the above (group 1) 1.7 2.1 4.2 -0.3 -2.0
Smoking status: Current 0.0 0.0 0.0 0.1 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.5 3.3 5.7 2.4 -0.9
Whole body water mass 0.3 1.5 2.1 -1.4 1.0
Leg predicted mass (right) 0.2 1.3 1.4 -1.2 1.1
Arm fat mass (left) 0.4 1.7 2.4 -1.5 1.0
Number of self-reported non-cancer illnesses 0.8 1.4 2.7 -1.6 0.4
Average weekly champagne plus white wine intake 0.1 0.1 0.2 -0.2 0.4
Miserableness 0.4 0.7 1.1 1.1 -0.5
Guilty feelings 0.1 0.1 0.1 0.4 0.4
Wears glasses or contact lenses 0.8 0.9 1.4 0.6 -1.2
Ever taken oral contraceptive pill 0.3 0.3 0.6 0.8 -0.0
Hearing aid user 0.4 0.5 1.0 1.0 -0.0
Mother’s age at death 1.0 1.2 1.9 0.7 -1.4
Financial situation satisfaction 0.9 1.1 1.5 1.2 0.8
Tinnitus: Yes, now most or all of the time 1.4 1.6 1.8 1.2 -1.4
Commuting to job workplace: Public transport 4.1 4.9 9.0 0.9 -3.0
Eye problems/disorders: Glaucoma 0.4 0.5 0.9 1.0 0.1
Medication: Blood pressure 0.5 1.0 1.3 -1.1 0.8
Pain type(s) experienced in last month: Hip pain 0.9 1.1 1.8 -1.3 -0.6
Supplements: Fish oil (including cod liver oil) 2.0 2.6 4.0 -2.0 -1.1
High cholesterol (Self-reported) 3.6 6.5 10.3 3.2 1.6
Medication: Bendroflumethiazide 1.5 2.2 4.2 -2.1 0.4
Medication: Paracetamol 0.3 0.4 0.6 -0.8 0.4
Medication: Lisinopril 1.9 2.4 4.8 -0.3 2.2
Medication: Atorvastatin 1.1 1.4 1.7 1.3 -1.0
Illnesses of father: High blood pressure 0.2 0.2 0.3 -0.6 0.2
Alcohol drinker status: Never 0.7 0.8 1.5 0.2 -1.2
Ever smoked 2.4 4.3 7.5 1.0 2.7
Basal metabolic rate 0.3 1.9 2.8 -1.7 1.0
Leg fat percentage (left) 0.1 0.2 0.5 -0.7 0.2
Arm fat-free mass (left) 0.4 1.8 2.9 -1.7 0.9
Number of operations (self-reported) 0.4 0.6 1.1 -0.2 1.0
Average weekly beer plus cider intake 0.9 1.4 2.7 -1.6 -0.2
Irritability 0.2 0.3 0.4 0.7 -0.4
Risk taking 0.2 0.2 0.4 0.3 0.6
Ever had prostate specific antigen (PSA) test 0.9 1.0 1.6 1.3 -0.6
Fractured/broken bones in last 5 years 0.6 0.8 1.5 -1.2 0.4
Age started oral contraceptive pill 0.8 1.0 2.0 -1.4 -0.2
Diastolic blood pressure, automated reading 2.1 6.5 12.9 -3.6 -0.2
Ever depressed for a whole week 1.7 2.1 2.7 1.2 1.6
Unable to work because of sickness or disability 1.3 1.7 2.4 1.5 -1.0
Commuting to job workplace: Cycle 1.3 1.5 2.9 1.7 0.4
Myopia 1.4 2.0 4.0 2.0 0.0
Vascular/heart problems diagnosed by doctor 1.3 3.6 6.7 2.6 -0.7
Cholesterol lowering medication 0.7 1.1 1.7 0.7 1.3
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 0.4 0.6 0.4
Pain experienced in last month 0.6 1.0 1.7 -0.4 -1.3
Supplements: Calcium 0.5 0.6 1.1 1.0 -0.3
Basal cell carcinoma (self-reported) 1.4 1.7 2.4 -1.0 1.6
Heart attack/myocardial infarction (self-reported) 1.7 2.1 3.2 1.8 -1.0
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 1.6 -1.3 -0.8
Heart disease (siblings) 0.7 0.8 1.3 0.5 1.1
Alcohol drinker status: Previous 0.0 0.0 0.0 0.2 -0.0
Pack years of smoking 1.5 2.2 4.2 0.5 -2.0
Impedance of whole body 0.1 0.4 0.5 -0.7 -0.5
Leg fat mass (left) 0.3 1.1 1.6 -1.3 0.8
Arm predicted mass (left) 0.3 1.6 2.4 -1.6 0.9