Hub : Genes

SNX18

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0780	0.0230	1.0e-04	0.053	0.045	0.051	0.051	0.053	4.4e-07	3.0e-06	6.8e-07	7.3e-07	4.1e-07
2	GTEx	Artery Aorta	0.1480	0.0530	4.1e-03	-0.005	NA	0.008	NA	-0.003	9.0e-01	NA	1.1e-01	NA	5.0e-01
3	GTEx	Brain Cerebellum	0.3380	0.1000	2.5e-03	0.212	NA	0.117	NA	0.195	6.6e-07	NA	2.5e-04	NA	2.0e-06
4	GTEx	Esophagus Mucosa	0.3300	0.0610	2.1e-07	0.276	NA	0.318	NA	0.297	1.3e-18	NA	9.4e-22	NA	3.6e-20
5	GTEx	Esophagus Muscularis	0.1950	0.0590	2.9e-04	0.099	NA	0.069	NA	0.085	1.4e-06	NA	5.6e-05	NA	7.4e-06
6	NTR	Blood	0.0533	0.0135	4.8e-08	0.029	0.035	0.030	0.036	0.029	1.0e-09	2.1e-11	4.4e-10	7.2e-12	1.1e-09
7	TCGA	Breast Invasive Carcinoma	0.0373	0.0146	1.3e-06	0.013	0.020	0.016	NA	0.021	7.4e-04	4.2e-05	2.4e-04	NA	2.8e-05
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0480	0.0254	7.7e-03	0.023	0.024	0.032	NA	0.031	1.1e-03	8.6e-04	1.4e-04	NA	1.7e-04
9	TCGA	Lung Squamous Cell Carcinoma	0.0644	0.0326	7.2e-03	0.000	0.016	0.004	NA	0.000	2.9e-01	5.4e-03	9.3e-02	NA	3.4e-01
10	TCGA	Prostate Adenocarcinoma	0.0539	0.0238	1.2e-04	0.046	0.034	0.018	NA	0.027	1.2e-05	1.7e-04	4.4e-03	NA	7.1e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.5	0.9	2.9	-0.2	-1.0	-1.6	0.1	0.4	-1.7	1.1	-0.1	0.6	0.6
Bipolar Disorder or Schizophrenia	1.0	2.3	9.5	0.7	-3.1	-1.6	-0.5	0.4	-2.5	0.6	-1.1	1.4	0.6
Depressed Affect (Nagel 2018)	0.7	1.4	4.5	1.6	1.2	0.1	-0.9	1.2	-1.1	-0.1	-1.5	-2.1	-0.2
Depression (Nagel 2018)	0.9	1.3	4.6	0.9	-0.2	-0.7	0.1	2.1	-1.2	0.8	-2.1	-0.9	-0.1
Intelligence (Savage-Jansen 2018)	0.6	1.7	4.1	-1.0	-1.1	-0.8	-1.3	1.3	0.1	-1.1	-2.0	-1.4	-2.0
Neuroticism (Nagel 2018)	0.6	1.5	5.9	-0.7	1.5	0.4	-1.6	-0.0	-0.0	-1.6	0.1	-2.4	-1.2
Schizophrenia (2018)	0.9	1.9	9.7	1.1	-3.1	-0.8	-0.8	0.2	-1.8	-0.2	-1.4	1.4	0.3
Schizophrenia vs Biploar Disorder	0.8	1.0	2.6	-0.1	0.4	1.0	-1.3	0.1	1.5	-1.0	0.1	-1.6	-1.4
Worry (Nagel 2018)	0.6	1.3	2.9	-0.9	1.6	0.4	-1.7	-1.0	0.6	-1.3	0.5	-1.7	-0.7
Alzheimer’s Disease (in mother)	0.6	0.7	2.7	0.4	-0.2	1.0	-1.7	-0.0	-0.1	-0.9	-0.7	-1.0	-0.8
Alzheimer’s Disease (in father)	0.4	0.5	1.4	1.2	1.0	-0.7	0.1	0.7	-0.8	-0.4	0.3	0.7	0.0
Alzheimer’s Disease (including proxy)	0.3	0.4	1.1	0.7	0.1	0.8	-0.6	0.7	-1.0	-0.8	-0.4	0.3	-0.5
Crohns Disease (2017)	0.7	1.5	5.6	-0.3	-0.4	-1.3	0.7	2.4	-1.2	-0.2	0.3	-1.8	-1.4
Irritable Bowel Disease (IBD)	0.5	1.2	5.9	0.1	-0.9	-1.2	1.2	2.4	-0.9	-0.4	-0.6	-0.5	-1.0
Ulcerative Colitis (UC)	0.5	0.9	1.8	-0.0	-1.4	-1.2	1.0	1.0	-0.4	-0.8	-1.2	0.9	-0.5
Major Depression (MDD)	1.2	1.5	4.4	2.1	0.0	-2.0	0.4	0.1	-1.1	1.4	0.0	0.4	1.8
Reaction Time	1.0	1.9	3.7	1.9	1.0	0.8	1.3	0.7	-1.4	1.6	-0.2	1.8	1.8
Verbal and Numeric Reasoning (VNR)	0.5	1.2	4.3	-0.4	-0.6	-0.7	-1.0	1.1	-1.4	-0.9	-2.1	0.3	-1.2
Breast Cancer	0.7	1.7	6.9	0.5	-0.1	2.6	0.2	-1.6	0.5	0.8	0.6	1.7	1.9
Ovarian Cancer	1.3	1.8	4.3	0.7	0.7	2.1	1.4	1.1	-2.0	0.5	1.0	1.7	1.0
Prostate Cancer	1.0	1.5	3.9	2.0	-0.3	0.6	1.0	0.7	-1.1	1.7	1.0	0.6	1.8
Age at First Birth	0.5	0.8	2.4	-1.5	-0.6	-1.2	1.2	0.6	0.3	-0.2	-0.5	-0.1	-1.1
Bipolar Disorder (2011)	1.4	1.4	5.8	0.5	-0.2	-2.4	1.7	0.5	-0.8	0.8	-0.7	1.0	1.2
Body Mass Index (BMI) (2010)	0.1	0.2	0.4	0.7	-0.2	0.0	-0.5	-0.1	0.5	0.5	0.4	-0.5	0.2
Coronary Artery Disease (CAD)	0.3	0.3	1.0	0.2	-0.5	0.8	-1.0	0.8	0.5	0.1	-0.2	-0.5	-0.5
Crohns Disease (2012)	0.6	1.0	5.3	-0.2	-0.1	-0.2	0.9	2.3	-1.2	0.8	0.1	-1.1	-0.6
Mean Putamen Volume	0.9	1.0	3.2	-1.3	1.0	-1.4	0.3	0.2	-0.0	-1.8	0.1	-0.5	-1.4
Fasting Glucose	1.3	1.6	5.1	-0.2	2.2	1.8	1.5	0.0	-0.2	0.1	2.2	-0.1	0.4
HbA1C	0.5	0.6	2.3	-0.3	0.6	1.2	-0.2	-1.5	-0.7	-0.4	0.6	0.6	0.6
HDL Cholesterol	1.0	1.6	6.9	-2.6	-0.1	-0.0	-0.1	-0.9	-0.2	-2.2	0.3	-0.4	-1.8
LDL Cholesterol	0.5	0.8	2.5	-1.4	-0.3	-0.2	0.7	-1.6	1.1	-1.1	-0.0	0.0	-0.4
Lupus	0.7	1.1	2.2	0.6	0.5	0.7	-1.3	-1.5	1.5	0.7	-0.8	0.8	1.4
Neuroticism (2016)	0.5	0.7	2.7	0.3	0.6	-0.7	-1.5	-0.8	-0.0	-0.3	-1.6	-0.7	0.1
Primary Biliary Cirrhosis	0.5	0.6	3.6	0.7	-0.8	-0.3	-0.6	-0.2	0.5	1.9	-0.3	-0.0	0.9
Rheumatoid Arthritis	1.1	1.6	3.2	-1.6	-1.3	0.4	-1.0	-1.8	1.7	-1.3	-0.4	-1.0	-1.2
Schizophrenia (2014)	0.9	2.0	11.6	0.0	-3.4	-1.2	-1.3	0.1	-1.4	-0.9	-1.3	0.4	-1.0
Triglycerides	0.5	0.8	3.3	0.7	0.1	-0.0	0.3	-0.3	-0.3	1.1	-0.7	1.8	1.4
Type 2 Diabetes (T2D) (2012)	1.7	2.0	6.4	-0.4	0.4	-0.0	-1.2	-1.3	1.1	-2.5	-2.1	-1.0	-1.7
Ulcerative Colitis	0.4	0.6	1.5	-0.6	-0.1	-0.0	0.8	0.9	-0.4	-0.8	-1.2	0.9	-0.8
Blood Eosinophil Count	0.2	1.6	10.7	0.1	1.8	3.3	0.3	-0.4	-0.7	-0.0	1.2	-0.3	0.4
Blood Platelet Count	0.1	1.1	4.2	-1.5	-0.7	-2.0	0.1	-0.5	-0.3	-1.0	0.9	-0.9	-1.0
Blood Red Count	0.1	1.4	4.0	-1.4	-1.1	1.4	-0.4	-0.7	-0.6	-1.3	0.2	-2.0	-1.2
Blood White Count	0.1	1.0	4.8	0.6	1.1	2.2	-0.5	-0.1	-1.6	-0.0	0.3	-0.9	0.2
Heel T-Score	0.2	1.2	7.2	0.4	-0.4	-2.7	-0.6	-0.8	1.6	0.2	1.0	0.2	0.5
BMI	0.1	0.4	1.4	1.2	0.2	0.5	-1.1	0.8	-0.4	0.7	-0.2	-0.1	0.5
Height	0.1	2.0	9.0	-1.3	-3.0	0.3	0.7	0.8	-1.2	-0.3	-1.5	2.0	-0.2
Waist Hip Ratio (WHR)	0.2	0.7	2.0	1.2	0.6	0.0	-0.2	-0.4	-1.4	0.8	1.0	-0.6	1.0
Systolic Blood Pressure	0.2	1.1	3.6	-1.2	-1.9	-1.7	-0.7	-0.2	-0.3	-0.5	0.6	-0.7	-1.2
Smoking Status	0.2	0.4	1.4	0.2	1.2	-0.3	-0.2	0.2	0.5	0.5	-0.1	0.9	0.8
Allergy or Eczema	0.3	0.9	1.7	-1.3	-0.3	-1.1	1.1	0.5	-1.3	-0.7	1.2	-0.3	-1.0
Cardiovascular Disease	0.2	0.6	1.3	-1.0	0.4	1.0	0.1	-0.3	0.6	-0.8	1.1	-0.6	-0.9
Hypothyroidism (self reported)	0.4	1.0	3.9	0.8	-0.7	-0.3	0.6	1.2	0.1	2.0	-1.4	0.5	0.8
Respiratory disease	0.8	1.7	4.5	-1.9	1.9	-0.5	-0.3	-0.9	2.1	-1.3	-0.5	-0.6	-1.2
Type 2 Diabetes (T2D) (2018)	0.8	1.6	13.2	-0.3	-3.6	0.5	0.0	0.8	-0.3	0.4	-0.9	0.1	-0.4
Lung FEV1/FVC ratio	0.8	4.0	26.7	1.5	2.1	5.2	1.0	0.1	-0.9	1.5	1.4	-0.2	1.0
Lung FVC	0.5	2.4	14.9	1.9	3.9	-0.0	-0.1	-0.5	0.1	1.3	1.0	-0.3	1.6
Neuroticism	0.4	1.0	3.7	0.0	1.2	-0.0	-1.5	-0.3	0.2	-1.3	-0.3	-1.9	-0.8
Chronotype (morning person)	0.9	2.1	8.0	-2.2	-0.4	-0.3	0.5	0.9	-0.5	-1.7	-0.7	-1.9	-2.8
Hair Pigment	0.0	1.3	5.0	-1.1	0.5	-1.3	-1.3	0.3	-0.7	-1.1	-2.2	0.0	-1.1
Tanning	0.1	0.7	1.4	-0.9	1.1	1.2	-0.6	-1.1	0.4	-0.9	-0.5	0.6	-0.3
Hand grip strength (left)	0.8	2.0	6.6	1.2	-0.1	1.5	0.3	0.8	-0.7	2.0	-0.8	2.6	1.9
Number of treatments/medications taken	0.3	0.5	1.0	-0.8	-0.6	0.6	-0.1	0.4	-0.9	-0.4	-1.0	0.5	-0.9
Average weekly spirits intake	0.9	1.1	3.8	-0.1	-0.6	0.6	-1.1	1.5	-0.4	0.5	-0.3	-2.0	-1.5
Sensitivity / hurt feelings	0.6	1.1	3.4	-1.5	1.6	0.8	0.1	-0.5	1.0	-1.8	0.3	-0.0	-0.8
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.7	0.5	0.1	-0.0	0.3	1.5	-1.2	0.9	-1.6	-0.5	0.2
Hearing difficulty/problems: Yes	0.9	1.3	3.7	-0.0	-1.4	-0.0	0.2	0.2	-1.4	1.3	1.1	1.9	1.6
Relative age of first facial hair	1.4	2.8	8.5	2.0	1.1	0.3	1.6	0.3	-0.9	2.5	1.2	1.7	2.9
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.2	-0.0	-1.5	0.8	-1.2	0.1	0.0	-1.0	-1.2	-0.3	-1.5
Ever used hormone-replacement therapy (HRT)	1.1	1.4	6.8	1.2	-1.2	-2.6	0.0	0.8	-1.6	0.5	-0.6	-0.2	-0.1
Ever had hysterectomy (womb removed)	1.0	1.1	3.3	1.3	-1.0	-1.8	-0.5	0.3	-1.8	0.8	-0.6	-0.2	0.5
Systolic blood pressure, automated reading	0.3	1.0	3.3	0.6	-1.4	-1.8	-1.0	-0.1	-0.6	0.8	0.8	-1.3	-0.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.1	0.2	0.3	-1.4	0.5	-0.1	1.2	0.5	-0.6	1.1	0.6
Angina	0.9	1.2	3.8	2.0	-0.5	-1.7	0.3	1.7	-0.5	0.9	0.8	0.1	0.6
Medication for hormone replacement therapy	1.0	1.1	2.7	-0.9	-1.6	-0.4	-0.3	0.2	-1.6	-1.3	-0.0	-0.7	-1.6
Vitamin and mineral supplements	0.9	1.2	4.2	0.7	-0.9	-0.7	1.1	2.0	-0.2	0.1	-0.9	-1.7	-1.0
Supplements: Zinc	0.6	0.6	2.0	0.1	0.3	-0.4	0.9	1.3	-0.7	0.9	1.4	0.1	0.4
Medication: Co-codamol	1.3	1.6	5.9	2.4	0.6	-1.0	2.0	-0.3	-0.1	1.1	0.3	0.4	1.7
Medication: Metformin	0.5	0.7	2.7	0.9	-1.7	0.6	-0.4	0.9	1.1	0.6	-0.2	0.1	0.7
Diabetes (father)	0.5	0.6	2.0	0.6	0.1	-0.7	0.0	-0.3	1.2	0.9	-1.4	0.5	0.8
Diabetes (mother)	0.9	1.1	3.1	1.4	0.1	1.1	1.2	1.6	-1.8	0.2	-0.6	0.4	-0.1
Severe depression (siblings)	0.4	0.5	0.9	0.3	-0.8	0.4	-0.2	-0.5	1.0	0.7	-0.5	0.9	1.0
Pack years adult smoking proportion	0.1	0.2	0.8	-0.2	0.9	-0.1	-0.8	0.1	-0.2	-0.2	-0.2	-0.5	-0.6
Impedance of leg (right)	0.2	1.2	4.5	-1.7	-0.1	2.1	1.3	-0.9	-0.5	-0.8	0.1	-0.4	-0.9
Leg fat-free mass (left)	0.1	0.7	3.1	0.4	0.2	-0.6	-0.7	1.8	0.4	0.2	-1.5	-0.2	-0.5
Trunk fat percentage	0.5	2.0	7.5	0.8	-1.0	1.4	1.3	2.5	-2.7	0.5	-0.7	-0.6	-0.2
Hand grip strength (right)	0.3	0.9	2.5	1.0	-0.1	0.4	0.1	1.2	-0.7	1.3	-0.8	1.6	0.8
Townsend deprivation index at recruitment	0.2	0.2	0.7	-0.5	-0.2	-0.4	0.3	-0.2	0.7	0.5	0.4	-0.8	-0.3
Current tobacco smoking	0.2	0.4	1.4	0.7	1.2	-0.3	-0.3	0.2	-0.0	0.0	-0.5	1.0	0.3
Average weekly fortified wine intake	0.1	0.1	0.3	0.4	0.3	0.3	0.0	0.6	0.5	0.0	0.1	0.1	0.2
Maternal smoking around birth	1.0	1.4	5.7	2.4	-0.1	-0.7	1.3	-0.2	-0.9	1.4	0.2	0.6	1.8
Fed-up feelings	0.7	1.3	3.0	1.7	1.7	-1.0	-0.1	0.8	-1.2	0.9	-0.6	-1.6	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	4.4	1.0	-0.6	-1.6	0.2	1.9	-1.5	1.1	-2.1	-0.6	0.1
Relative age voice broke	0.4	0.7	2.2	0.5	1.2	0.5	0.3	-0.6	0.5	0.8	0.2	1.1	1.5
Taking other prescription medications	0.6	0.9	4.3	0.0	-0.2	-0.2	-0.0	1.4	-1.3	-0.3	-2.1	-0.2	-1.1
Age when periods started (menarche)	0.5	1.3	5.7	0.5	1.6	0.1	0.8	0.1	2.4	1.3	0.8	0.2	1.1
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	9.3	0.1	-0.1	-3.0	-0.1	-0.7	-1.0	0.1	-0.4	0.7	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.6	0.2	-1.3	-0.3	-0.2	0.2	-0.9	-0.8	-0.4	-1.2	-0.9
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.3	-0.4	-1.1	-0.9	1.0	-0.1	-0.7	0.2	-0.9	0.7	-0.1
Qualifications: CSEs or equivalent	1.6	2.1	4.5	2.1	-0.6	0.9	1.0	0.7	-1.6	1.7	-0.5	2.0	2.0
Serious illness, injury or assault to yourself	0.4	0.5	1.6	0.0	0.8	0.3	-1.2	-1.2	0.1	-0.3	0.5	0.6	0.4
High blood pressure	0.2	0.7	2.8	-0.0	0.1	1.2	0.9	0.4	-0.8	-0.3	0.5	-1.7	-0.8
Hayfever, allergic rhinitis or eczema	0.3	0.8	3.1	-0.3	-0.5	-0.9	0.7	-0.3	-1.4	-0.5	1.8	0.7	0.3
Multivitamins +/- minerals	1.1	1.4	4.0	-0.1	1.6	0.6	-1.0	-1.2	0.4	0.7	0.9	2.0	1.7
Stomach or abdominal pain in last month	0.5	0.6	2.4	0.4	1.5	0.7	-0.6	-0.5	1.1	0.9	0.1	-0.7	0.5
Supplements: Glucosamine	0.5	0.7	2.5	-1.0	-0.0	-0.0	0.6	-0.9	0.2	-1.6	-0.4	-0.0	-1.3
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.5	-0.5	0.6	0.5	0.8	-0.8	0.9	0.4	-0.8	1.2	0.3
Medication: Atenolol	0.6	0.7	4.2	1.1	-0.2	2.0	-0.3	0.2	0.0	-0.1	-1.1	-0.3	-0.1
Medication: Levothyroxine sodium	0.5	0.8	3.4	1.3	-0.9	0.5	-0.1	1.1	-0.1	1.8	-0.6	-0.1	0.8
Sitting height	0.2	1.6	6.8	-1.5	-0.7	-1.0	-0.3	0.5	1.3	-0.6	-2.6	-0.8	-1.7
Chronic bronchitis/emphysema (father)	0.9	1.0	2.8	0.4	-1.4	1.5	1.3	0.7	-0.5	0.3	1.7	-0.6	-0.1
High blood pressure (mother)	0.6	0.8	1.6	-0.8	1.2	0.6	1.2	-1.3	0.4	-0.5	0.5	-1.0	-0.7
Body mass index (BMI)	0.3	1.1	5.1	1.7	-0.1	-0.1	0.1	2.2	-1.4	0.9	-0.1	-0.8	0.2
Impedance of leg (left)	0.3	1.3	6.4	-1.1	-0.3	2.5	1.9	-1.1	-0.8	-0.0	0.5	0.3	0.1
Leg predicted mass (left)	0.1	0.7	2.9	0.3	0.2	-0.5	-0.7	1.7	0.4	0.1	-1.6	-0.3	-0.5
Trunk fat mass	0.4	1.7	6.8	0.9	-0.9	0.9	0.9	2.6	-2.1	0.5	-1.1	-0.6	-0.3
Waist circumference	0.4	1.4	4.2	1.8	-0.7	-0.0	-0.1	2.1	-1.9	1.2	-0.3	-0.7	0.6
Number of incorrect matches in round	0.5	0.7	2.2	0.9	0.3	-0.9	-1.5	-1.5	0.7	-0.1	-0.1	0.6	0.8
Past tobacco smoking	0.2	0.3	1.2	0.7	0.2	-0.1	-0.3	-0.4	-0.7	-0.4	1.1	0.5	0.5
Alcohol usually taken with meals	0.8	1.3	3.4	-0.4	-1.3	-0.4	-1.9	0.4	1.3	-1.3	-0.5	-1.2	-1.7
Nervous feelings	0.7	1.3	4.1	-0.5	1.7	-0.0	-2.0	-1.0	0.3	-1.0	0.8	-1.4	-0.6
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.9	2.2	0.9	1.5	0.7	-1.0	0.7	1.1	0.0	-1.1	-1.0	0.3
Hearing difficulty/problems with background noise	0.5	0.8	4.0	-0.5	0.1	0.3	0.1	-0.4	0.1	1.1	0.5	2.0	1.4
Hair/balding pattern: Pattern 2	1.3	1.7	4.5	-1.0	1.5	-0.4	-2.1	-2.1	1.3	-1.1	-0.5	1.3	-0.0
Had menopause	1.0	1.2	4.6	1.2	-0.7	-2.1	0.9	1.2	-1.6	1.0	-0.1	-0.3	0.3
Had other major operations	0.9	1.1	4.2	0.9	0.0	-0.1	1.2	-0.4	-0.9	2.0	0.4	1.1	1.6
Forced vital capacity (FVC)	0.5	1.8	13.3	0.4	3.6	0.6	0.3	-0.9	0.7	0.3	1.2	0.6	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.2	0.4	-1.5	-0.4	-0.8	0.2	-0.9	-0.9	-0.3	-0.2	-0.6
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	3.0	1.6	0.2	0.6	-0.1	0.1	-1.2	1.6	1.0	0.3	1.7
Qualifications: None of the above	0.7	1.5	4.6	2.1	0.3	0.5	1.4	0.7	-0.8	1.9	-0.3	-1.5	1.1
Financial difficulties in last 2 years	0.6	0.9	3.8	1.6	1.9	-0.0	-0.5	-0.2	0.1	1.0	0.2	-0.3	1.0
Mouth/teeth dental problems	0.8	1.2	7.3	-2.7	0.6	0.2	0.7	-0.6	0.8	-1.1	0.2	0.5	-1.1
Heart attack	1.1	1.5	3.1	0.3	0.2	0.5	-1.5	1.2	0.6	-1.8	-1.0	-1.7	-1.8
Allergy	0.3	0.6	1.4	0.8	-0.3	0.5	-0.7	0.7	1.0	0.9	-0.9	-1.2	-0.3
Pain all over the body in last month	1.3	1.3	4.0	0.8	-0.3	-0.5	1.5	0.2	-0.3	1.8	2.0	0.4	1.7
Diabetes (self-reported)	1.0	1.5	8.8	0.5	-3.0	0.2	-0.2	1.2	-0.5	1.1	-1.6	0.3	0.5
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	1.7	-0.9	-0.9	0.2	-1.1	-0.8	-0.9	-1.3	-0.4	1.3	-0.3
Medication: Ramipril	0.3	0.4	1.0	-0.9	-0.5	-0.5	0.7	-0.1	0.0	-0.6	0.3	-0.8	-1.0
Medication: Simvastatin	0.1	0.1	0.4	0.1	-0.2	0.5	-0.6	-0.1	0.4	-0.2	0.1	0.3	0.0
Fluid intelligence score	0.8	1.6	4.5	-0.9	-0.1	0.8	-2.0	0.6	-0.3	-1.6	-1.4	-1.1	-2.1
Illnesses of siblings	0.3	0.4	1.8	-0.2	-0.1	-1.3	-0.8	0.4	0.7	-0.6	-0.1	-0.5	-0.5
Neuroticism score	0.3	0.6	2.0	0.1	1.4	0.4	-0.9	0.2	-0.4	-0.8	-0.5	-1.3	-0.6
Weight	0.2	1.0	5.7	1.0	-0.4	-0.2	0.1	2.4	-0.8	0.6	-1.5	-0.5	-0.3
Impedance of arm (right)	0.3	1.6	5.6	-2.4	-1.1	0.2	0.8	-1.9	-1.0	-1.5	-0.3	0.4	-1.0
Arm fat percentage (right)	0.4	1.4	6.9	0.8	-1.3	0.4	0.3	1.9	-2.6	0.2	-0.0	-0.9	-0.2
Trunk fat-free mass	0.1	0.8	3.4	0.4	-0.2	-1.0	-0.5	1.5	1.1	0.5	-1.8	0.0	-0.1
Hip circumference	0.4	1.6	8.6	1.1	-1.0	0.1	0.6	2.9	-1.5	1.0	-0.9	-1.0	-0.3
Time employed in main current job	0.6	0.7	4.2	0.9	-0.6	0.1	-0.5	0.4	-2.1	0.2	-0.4	-1.0	-0.1
Alcohol intake versus 10 years previously	1.6	2.3	8.9	-1.1	-0.2	2.1	-0.2	-1.8	0.4	-1.3	1.4	-3.0	-1.4
Father’s age at death	1.1	1.4	4.8	-2.2	-1.0	-0.4	1.4	-0.5	0.3	-1.8	-0.6	0.7	-1.4
Worrier / anxious feelings	0.4	0.8	2.3	-1.1	1.1	1.5	-0.5	-0.5	0.1	-0.8	1.1	-1.0	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	4.0	0.7	0.1	-0.3	-1.3	0.2	-0.5	0.9	-2.0	1.0	0.9
Falls in the last year	0.7	1.0	3.6	-0.8	1.1	-0.3	-1.5	-0.7	1.9	-0.8	-0.7	0.1	-0.7
Hair/balding pattern: Pattern 3	0.4	0.6	1.8	0.5	0.4	-0.5	1.3	0.6	0.4	1.2	-0.1	1.1	0.9
Number of live births	0.6	0.8	2.9	1.7	0.1	-0.4	-0.2	0.3	1.6	1.0	-0.6	0.0	1.0
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	19.9	1.0	4.5	1.8	0.4	-0.9	0.9	0.9	1.8	0.7	1.6
Pulse rate	1.4	2.4	8.2	0.2	2.9	1.5	2.6	0.3	0.4	1.5	1.4	0.7	1.5
Happiness	0.8	0.9	3.6	0.7	1.3	-0.6	-1.3	0.5	-0.2	-0.5	-1.9	-0.7	-0.7
Noisy workplace	0.4	0.6	2.8	0.4	-0.7	1.7	-1.0	-0.1	-0.5	0.4	-0.7	0.0	0.4
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.0	-1.3	-1.1	-0.2	-1.0	0.4	-0.1	-0.7	-0.9	-0.6	-1.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.0	0.9	-1.4	-0.4	-0.3	0.7	0.6	1.2	0.6	-0.6	0.3
Mouth/teeth dental problems: Dentures	0.4	0.6	1.6	1.2	-0.4	-0.2	-1.1	-0.6	0.8	0.0	-1.2	-0.9	0.1
Asthma	0.3	0.7	1.9	-1.4	1.4	-0.5	0.3	-1.1	0.6	-0.9	-0.2	0.1	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	3.1	0.3	-0.1	-1.8	0.3	0.7	-1.1	-0.3	1.0	-0.9	-0.4
Medication: Cholesterol lowering	0.7	1.0	2.8	-1.4	0.0	0.0	-1.4	-0.7	0.9	-1.7	-0.3	0.2	-1.5
Depression (self-reported)	0.9	1.1	5.2	1.1	-0.7	0.1	-2.3	0.7	-1.3	0.9	-0.4	0.4	0.7
Medication: Lansoprazole	0.7	0.8	3.1	1.8	1.3	0.3	0.8	0.1	-0.5	0.7	0.3	-1.1	0.9
Prospective memory result	0.9	1.2	3.3	0.8	-0.1	0.4	0.5	-1.1	-1.8	0.2	1.1	1.8	1.3
Lung cancer (father)	1.5	1.7	6.4	2.5	0.1	0.2	0.9	0.6	-0.9	1.6	1.7	-1.0	1.6
Illnesses of mother	0.3	0.3	1.0	0.4	-0.8	0.2	-1.0	0.4	-0.0	0.8	-0.6	0.0	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	8.5	1.3	2.9	1.5	-0.0	-0.4	0.7	0.4	0.9	-0.2	0.9
Pulse wave Arterial Stiffness index	0.5	0.6	2.0	-0.3	1.2	-1.4	-0.4	0.2	1.0	0.3	0.2	-0.9	-0.4
Impedance of arm (left)	0.2	1.1	3.2	-1.8	-0.9	1.0	1.3	-1.0	-1.2	-1.1	0.0	0.1	-0.9
Arm fat mass (right)	0.3	1.4	5.8	1.2	-0.8	0.3	0.5	2.4	-2.2	0.8	-0.4	-0.6	0.1
Trunk predicted mass	0.1	0.8	3.2	0.4	-0.2	-1.0	-0.4	1.4	1.2	0.5	-1.8	-0.0	-0.2
Standing height	0.1	1.3	8.5	-1.2	-0.6	0.0	0.4	0.6	0.9	-0.3	-2.9	0.7	-0.8
Length of working week for main job	1.3	1.4	4.5	-0.7	0.9	1.6	1.6	-1.1	1.2	0.2	2.1	0.8	0.6
Exposure to tobacco smoke at home	0.6	0.7	1.7	-1.3	0.5	-1.1	0.3	-0.0	-0.8	-0.3	0.9	-0.9	-1.0
Breastfed as a baby	0.3	0.4	1.7	0.8	0.3	0.6	0.1	1.3	0.7	0.0	0.2	-0.9	-0.2
Tense / ‘highly strung’	0.5	0.8	2.9	-0.4	1.2	-0.8	-1.7	-1.2	0.1	-0.6	0.1	0.5	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.9	4.4	17.0	2.5	4.1	2.4	0.4	0.7	-0.3	2.6	1.3	-0.3	2.3
Hair/balding pattern: Pattern 4	0.4	1.0	3.7	0.1	-1.3	0.8	-0.4	1.2	-0.8	0.1	1.9	-1.1	-0.4
Birth weight of first child	0.8	1.4	3.7	-0.4	1.3	1.8	1.4	-0.5	1.9	0.6	-1.2	1.1	0.3
Peak expiratory flow (PEF)	2.2	5.1	13.0	2.5	3.6	0.9	1.5	-0.6	0.6	3.0	2.3	1.7	3.3
Pulse wave reflection index	0.8	1.0	4.8	0.8	-0.1	-2.2	-1.0	1.4	-0.3	0.6	0.5	-1.1	0.1
Ever highly irritable/argumentative for 2 days	2.3	2.8	7.6	1.6	2.8	1.4	1.2	2.6	-1.1	0.9	1.5	-1.7	-0.2
Loud music exposure frequency	0.4	0.4	1.4	-0.7	0.2	-0.6	0.9	-0.5	0.2	1.2	0.2	-1.0	0.1
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	4.5	0.6	-0.6	0.0	0.4	0.3	-2.1	1.1	0.7	1.8	1.5
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.5	1.1	0.5	0.4	0.8	1.6	-0.3	1.4	1.0	-1.1	0.6
Blood clot in the leg (DVT)	1.0	1.3	5.4	-1.4	-0.5	0.2	0.7	-1.7	-0.8	-0.9	0.3	2.3	0.6
Medication: Paracetamol	0.6	0.9	3.5	0.8	0.1	0.2	1.9	-0.5	-1.9	0.5	0.5	0.3	0.9
Headache pain in last month	0.3	0.5	3.4	0.3	1.8	-0.2	-0.1	-0.6	-1.0	0.0	0.3	-0.1	0.7
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.8	1.6	0.4	0.2	0.7	0.2	-1.2	1.5	-0.0	0.8	1.7
Glaucoma (self-reported)	0.6	0.7	3.0	-0.8	-1.7	-0.4	0.2	0.4	0.9	-0.8	-0.2	-0.1	-1.1
Gout (self-reported)	0.6	0.9	2.4	-0.6	-1.3	-1.6	0.5	0.6	0.6	-0.1	-0.8	-1.0	-1.3
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	3.3	0.9	-1.0	0.0	0.1	1.4	0.5	1.8	-1.4	-0.9	0.1
Medication: Amlodipine	0.5	0.8	2.5	0.4	-0.4	0.6	-0.8	-0.8	0.4	1.1	1.6	0.7	1.2
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.1	0.3	1.2	0.9	1.4	-0.1	0.5	0.8	0.2	0.3	0.9
Birth weight	0.7	1.5	3.9	-1.4	0.6	-0.2	0.1	-0.5	1.6	-1.5	0.4	-2.0	-1.9
Chronic bronchitis/emphysema (mother)	0.7	0.9	1.8	0.7	1.0	-0.9	0.2	-0.3	1.1	1.1	1.3	0.6	1.3
High blood pressure (siblings)	0.1	0.1	0.7	-0.3	-0.3	0.5	0.9	0.1	-0.4	0.2	0.0	-0.2	-0.1
Forced vital capacity (FVC), Best measure	0.3	1.0	6.7	1.3	2.6	0.4	0.4	-0.1	0.0	0.4	0.6	0.3	1.0
Body fat percentage	0.5	2.1	7.2	1.1	-0.9	1.1	1.2	2.7	-2.7	0.6	-0.5	-1.0	-0.2
Leg fat percentage (right)	0.5	2.0	7.3	1.2	-1.0	1.0	0.4	2.7	-1.9	0.3	-0.3	-2.1	-0.8
Arm fat-free mass (right)	0.2	0.9	5.3	1.1	0.3	-0.1	0.1	2.3	0.3	0.9	-1.2	0.0	0.3
Exposure to tobacco smoke outside home	1.4	1.9	8.0	-0.7	-0.0	0.0	-2.8	-1.4	1.8	-1.0	-1.4	-0.9	-1.0
Comparative body size at age 10	0.3	0.8	3.5	0.3	-0.1	-0.1	0.3	1.7	-0.7	0.1	0.8	1.9	0.5
Number of full brothers	0.5	0.7	1.7	1.0	0.3	1.1	0.9	-0.4	0.4	0.9	0.0	1.0	1.3
Worry too long after embarrassment	0.7	1.2	3.3	-1.5	-0.7	1.8	0.8	-0.6	-0.5	-1.2	1.7	0.4	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.3	0.6	0.5	-0.9	0.2	-0.7	0.7	0.7	0.3	0.9	1.1
Wheeze or whistling in the chest in last year	0.2	0.3	1.8	0.3	1.3	-0.2	0.7	-0.1	-0.3	0.3	0.6	-0.1	0.4
Number of children fathered	1.0	1.2	4.8	0.5	-0.8	0.3	0.7	2.2	-1.0	1.0	-1.8	0.1	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.9	-0.3	-0.2	-1.4	0.1	-0.9	0.2	-0.1	0.3	0.3	-0.0
Age at first live birth	0.8	1.4	3.4	-1.3	1.0	-0.9	-0.4	0.5	1.2	-1.8	-1.5	-0.4	-1.7
Pulse wave peak to peak time	0.5	0.6	2.1	0.4	-1.1	1.4	0.4	0.1	-1.1	-0.2	-0.4	0.9	0.5
Health satisfaction	1.0	1.4	3.4	1.3	1.5	1.8	1.1	1.1	-0.3	1.6	0.8	0.1	0.9
Shortness of breath walking on level ground	1.3	1.6	8.0	-0.0	2.8	-0.4	0.8	-0.7	1.3	0.7	1.8	-0.9	0.3
Qualifications: College or University degree	1.6	5.1	16.3	-3.6	-0.7	-1.3	-2.0	-0.5	1.3	-3.0	-1.0	-1.8	-4.0
Eye problems/disorders: None of the above	0.1	0.1	0.4	0.1	-0.1	0.5	-0.7	-0.4	-0.6	-0.2	-0.2	-0.3	-0.1
Mouth/teeth dental problems: Loose teeth	1.6	1.9	5.5	1.0	-1.6	-0.9	-1.4	2.3	-1.3	0.9	-1.8	-1.0	-0.3
Emphysema/chronic bronchitis	0.6	0.7	4.3	-0.2	-0.2	-0.1	0.1	2.1	-0.4	0.2	-1.2	0.2	-0.9
Medication for pain relief, constipation, heartburn	0.6	1.0	6.4	-0.2	0.0	-0.5	-1.1	-1.0	2.5	0.4	0.7	-0.6	0.5
Neck or shoulder pain in last month	0.5	0.6	2.5	1.1	0.5	-1.6	-0.6	0.6	-1.1	-0.7	-0.1	-0.1	0.0
Medication: Blood pressure	0.8	1.3	4.1	-1.5	0.1	-0.5	-0.2	0.8	0.6	-1.2	0.4	-2.0	-2.0
Angina (self-reported)	1.0	1.3	3.6	1.8	-0.7	-1.8	0.7	1.9	-0.7	0.9	0.9	0.1	0.5
Migraine (self-reported)	1.0	1.3	4.9	0.4	1.4	1.4	2.2	1.5	0.1	0.0	-0.0	-0.7	-0.7
Medication: Ibuprofen	1.0	1.1	3.9	0.8	-0.3	-1.2	0.4	0.8	-1.9	0.0	2.0	-0.8	0.2
Medication: Allopurinol	1.0	1.3	6.9	-0.4	-0.9	-0.7	0.0	0.6	-0.1	-0.3	-1.1	-2.6	-1.8
Medication: Omeprazole	1.0	1.2	4.5	0.4	-0.4	-0.0	2.1	1.4	-1.3	1.3	0.2	1.2	0.3
Medication: Seretide 50 evohaler	0.5	0.6	3.5	0.3	1.0	-1.9	-0.2	0.2	0.4	-0.4	-0.6	0.7	0.0
Mean time to correctly identify matches	0.8	1.6	5.1	2.3	-0.4	0.3	0.9	1.2	-1.4	1.7	-0.1	0.9	1.6
Heart disease (mother)	0.7	0.8	2.4	-0.6	1.0	-0.3	0.1	-0.7	1.5	0.9	-0.0	1.5	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.2	5.1	12.0	2.3	-0.4	0.6	2.9	1.6	-1.7	3.5	1.4	2.8	3.0
Whole body fat mass	0.4	1.5	6.7	1.0	-0.7	0.8	0.8	2.6	-2.0	0.5	-0.9	-0.8	-0.2
Leg fat mass (right)	0.3	1.3	6.4	1.2	-0.2	0.6	0.3	2.5	-1.4	0.4	-0.7	-1.5	-0.5
Arm predicted mass (right)	0.2	0.9	4.2	0.8	0.4	-0.2	-0.0	2.1	0.8	0.6	-1.6	0.0	-0.1
Pulse rate, automated reading	0.7	2.3	8.2	-1.1	2.9	2.4	1.7	-0.7	1.2	-0.1	1.8	-0.4	0.0
Alcohol intake frequency.	1.2	2.7	5.4	1.0	1.9	2.1	2.1	1.5	0.2	1.6	2.3	-1.7	0.8
Comparative height size at age 10	0.3	1.7	5.2	-0.7	-2.2	0.8	-0.8	1.2	-1.5	0.3	-2.3	-0.1	-0.9
Number of full sisters	2.3	2.8	5.2	1.9	1.3	2.1	2.1	1.3	-0.5	2.2	1.1	1.2	2.3
Suffer from ‘nerves’	0.4	0.6	2.3	0.4	-0.2	-0.4	-0.2	-0.6	-1.5	1.2	0.9	-0.4	0.8
Overall health rating	0.7	1.4	2.5	1.1	1.1	0.6	1.6	1.5	-1.2	1.4	0.5	1.2	1.3
Chest pain or discomfort	0.5	0.8	1.7	1.2	-0.0	1.2	1.1	0.3	0.3	1.3	0.1	1.1	0.7
Had major operations	1.4	1.7	3.3	-1.1	-1.3	-0.5	-1.6	-0.9	0.6	-1.4	-1.7	-1.4	-1.8
Age at last live birth	1.4	2.1	5.2	-1.7	-0.1	-0.8	-0.8	-0.3	2.2	-2.3	-1.6	-0.9	-1.7
Family relationship satisfaction	1.3	1.5	7.9	-1.0	0.0	-0.5	-1.9	0.0	-0.1	-1.0	-2.8	0.4	-1.1
Leg pain on walking	0.9	1.2	3.7	0.2	0.6	1.4	1.2	1.9	1.0	1.3	-1.2	0.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.6	3.3	1.8	1.2	0.9	0.8	1.5	-0.5	1.6	1.1	1.0	1.6
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.8	-0.2	-0.4	0.1	-1.0	-0.5	-1.3	0.5	0.9	0.9	0.9
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.6	-1.3	0.0	0.6	0.3	-0.2	-0.2	-1.2	-0.1	0.2	-1.0
Medication: Aspirin	0.3	0.4	1.4	-0.4	0.5	1.0	-0.7	-0.4	0.3	-0.9	-0.1	1.2	0.1
Supplements: Vitamin C	0.7	0.8	2.8	-0.2	0.1	0.4	0.9	-0.4	-1.2	0.6	1.3	1.7	0.9
Knee pain experienced in last month	0.8	1.2	2.4	-1.1	-0.7	1.5	-1.3	0.4	0.5	-1.3	-1.4	-0.0	-1.6
Hypertension (Self-reported)	0.2	0.5	2.0	-0.3	0.1	1.0	0.8	0.2	-0.3	-0.4	0.7	-1.4	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	3.2	1.4	1.3	1.8	-0.6	0.9	-0.2	1.3	-1.5	0.1	0.2
Illnesses of father: Heart disease	0.7	0.9	3.1	-0.6	-0.3	-0.7	-0.1	-0.5	0.7	0.9	-1.7	1.7	0.8
Illnesses of siblings: Diabetes	0.3	0.4	1.1	0.5	0.9	0.6	1.1	-0.2	0.3	0.4	-0.7	-0.7	0.3
Smoking status: Previous	0.3	0.4	0.7	-0.8	-0.6	0.8	0.3	0.1	0.8	0.5	-0.8	-0.7	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.9	0.0	-0.8	0.2	0.8	-0.0	-0.4	1.0	-0.3	0.2	0.5
Whole body fat-free mass	0.1	0.8	3.1	0.5	-0.0	-0.7	-0.5	1.7	0.7	0.5	-1.8	-0.1	-0.2
Leg fat-free mass (right)	0.1	0.5	2.3	0.5	0.1	-0.5	-0.4	1.5	0.3	0.5	-1.4	0.2	0.1
Arm fat percentage (left)	0.4	1.6	6.2	0.9	-1.2	0.7	0.8	2.4	-2.5	0.3	0.0	-1.0	-0.3
Average weekly red wine intake	1.0	1.4	4.7	1.0	-1.3	0.4	0.7	2.2	-0.7	1.7	-0.2	1.4	0.8
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.9	0.2	-0.1	-0.5	-0.6	-0.0	-0.0	0.3	0.3	0.9	0.4
Mood swings	0.5	0.9	1.9	1.4	0.8	-1.3	0.5	0.8	-1.3	0.1	-0.5	-1.2	0.0
Loneliness, isolation	0.9	1.2	2.6	1.6	1.6	1.5	-0.3	1.5	-0.8	0.8	0.3	-0.2	1.0
Long-standing illness, disability or infirmity	0.7	1.0	4.6	0.1	-1.3	0.1	-0.2	2.1	-1.4	-0.1	-0.5	0.6	-1.0
Ever had bowel cancer screening	1.7	1.9	7.3	-0.3	0.6	0.6	-1.8	-2.4	2.7	-0.9	0.3	-1.1	0.1
Diabetes diagnosed by doctor	1.2	2.0	7.6	1.4	-2.8	0.8	0.3	1.9	-0.5	2.0	-1.1	0.1	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	4.0	-0.5	1.5	2.0	0.1	-0.5	1.0	0.6	-0.5	0.4	-0.0
Friendships satisfaction	0.3	0.4	1.6	0.4	-0.6	0.1	-0.7	1.0	-1.2	-0.2	-0.3	-0.5	-0.3
Qualifications: nursing, teaching	0.4	0.6	2.7	0.8	0.5	-0.5	1.6	1.2	-0.3	0.6	-0.1	0.6	0.2
Commuting to job workplace: Walk	0.7	0.8	3.0	-0.0	-1.7	-0.9	0.6	0.5	-1.3	-0.2	0.8	-0.7	-0.4
Eye problems/disorders: Cataract	0.6	0.7	2.3	0.6	-0.2	0.3	1.5	1.1	-0.0	1.2	0.5	0.5	1.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.7	0.3	-0.7	0.9	-0.0	-1.1	-0.1	-0.3	0.7	1.3	0.6
Medication for cholesterol	0.1	0.2	0.8	0.2	0.1	-0.2	-0.3	0.9	0.0	-0.2	0.8	0.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.3	14.7	1.4	0.8	3.8	0.9	0.2	-0.5	1.9	0.1	-0.2	1.1
Back pain experienced in last month	0.6	0.9	4.3	2.1	-0.5	-0.2	0.4	1.5	-0.3	0.2	-0.7	-1.0	0.2
Mineral and other dietary supplements	0.4	0.5	1.4	0.9	1.1	-0.1	-0.1	0.5	1.1	0.4	-0.3	-1.2	0.2
Breast cancer (self-reported)	1.1	1.3	3.4	1.8	1.8	0.7	0.5	0.5	-0.6	1.8	0.3	0.6	1.4
Asthma (self-reported)	0.4	0.8	2.3	-1.5	1.2	-1.0	0.3	-1.1	0.9	-0.8	-0.2	0.0	-0.4
Osteoporosis (self-reported)	0.3	0.4	0.7	-0.8	0.6	0.3	0.7	0.1	-0.7	-0.5	0.5	-0.7	-0.8
Osteoarthritis (self-reported)	0.6	0.8	2.1	0.4	-0.9	0.9	-1.4	-1.2	-0.7	-1.2	0.2	0.7	-0.1
Medication: Aspirin	0.2	0.3	1.0	-0.1	0.2	1.0	-0.2	-0.2	-0.3	-0.6	0.3	0.9	0.3
Medication: Gliclazide	1.2	1.3	3.2	0.5	-1.0	-0.2	1.8	1.1	-0.3	1.6	0.7	1.3	1.6
Illnesses of father: None of the above (group 1)	1.1	1.3	5.5	0.9	2.3	1.1	-0.7	-0.2	-1.3	-0.3	1.7	-0.8	0.0
Smoking status: Current	0.2	0.4	1.4	0.6	1.1	-0.7	-0.1	0.1	0.1	0.1	-0.3	1.2	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	2.6	1.1	1.6	0.4	-0.1	0.4	0.4	1.1	0.7	-0.8	0.5
Whole body water mass	0.1	0.7	2.7	0.4	0.0	-0.8	-0.5	1.6	0.8	0.5	-1.6	-0.0	-0.2
Leg predicted mass (right)	0.1	0.5	2.3	0.5	0.1	-0.5	-0.4	1.5	0.3	0.5	-1.4	0.2	0.0
Arm fat mass (left)	0.3	1.3	6.0	1.0	-0.6	0.2	0.7	2.5	-1.8	0.6	-0.6	-0.8	-0.2
Number of self-reported non-cancer illnesses	1.3	2.2	5.5	-0.6	-2.1	0.9	-0.5	1.1	0.2	-1.4	-2.3	-1.4	-2.3
Average weekly champagne plus white wine intake	1.1	1.5	4.4	2.1	-0.8	-0.6	0.8	1.0	-1.4	1.2	0.8	0.9	1.7
Miserableness	1.4	2.4	6.2	2.1	-0.0	0.3	0.1	2.4	-1.9	0.4	-1.9	-2.5	-0.8
Guilty feelings	0.3	0.4	1.6	-0.5	0.7	0.8	0.2	-0.1	-0.6	-0.7	1.3	0.5	0.3
Wears glasses or contact lenses	0.2	0.2	0.8	0.0	-0.1	-0.7	0.0	0.1	0.3	0.9	-0.0	0.7	0.3
Ever taken oral contraceptive pill	0.6	0.7	2.4	-1.2	1.6	-0.5	-0.5	-0.8	1.2	-0.2	0.1	-0.2	-0.2
Hearing aid user	0.6	0.7	1.6	-0.9	-1.2	-1.2	-0.4	0.7	0.5	-0.8	-0.7	-0.3	-0.9
Mother’s age at death	1.3	1.6	5.7	-0.7	1.7	0.0	-1.0	-0.3	2.4	-1.6	-0.8	-0.7	-1.3
Financial situation satisfaction	1.0	1.3	2.7	1.4	1.7	-1.0	0.2	1.5	-0.4	1.4	-1.1	0.9	0.8
Tinnitus: Yes, now most or all of the time	0.7	0.8	5.0	0.4	0.3	-0.8	-0.4	-0.0	0.2	0.3	2.2	-1.5	-0.1
Commuting to job workplace: Public transport	0.7	0.9	3.3	-0.7	-0.3	-0.5	-0.6	0.2	-0.5	-1.2	-0.0	-1.8	-1.5
Eye problems/disorders: Glaucoma	0.7	0.8	2.1	-1.0	-0.7	0.7	0.3	1.0	0.7	-1.2	0.3	-0.8	-1.4
Medication: Blood pressure	0.3	0.6	3.3	0.8	0.7	1.8	0.4	-0.7	-0.2	0.3	-0.5	-0.6	0.1
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.2	0.5	1.0	0.6	-0.5	-1.0	0.3	0.3	-0.5	0.6	1.1
Supplements: Fish oil (including cod liver oil)	1.1	1.5	7.8	-0.0	-2.8	-0.6	-0.1	-0.2	-2.2	0.0	-0.3	1.3	0.3
High cholesterol (Self-reported)	0.3	0.6	3.5	0.1	1.9	0.4	-0.2	-0.1	1.2	0.2	0.0	0.6	0.1
Medication: Bendroflumethiazide	0.4	0.6	1.2	-0.6	-1.0	0.0	0.9	-0.4	-0.8	-0.5	1.1	-1.0	-0.7
Medication: Paracetamol	0.8	1.3	4.6	1.0	-0.2	0.7	1.2	-0.5	-2.1	0.5	1.9	-0.1	1.0
Medication: Lisinopril	1.2	1.5	4.4	-0.9	1.7	-0.4	1.8	-2.1	1.1	0.2	1.3	0.1	0.7
Medication: Atorvastatin	0.5	0.6	2.8	0.3	1.0	-1.7	0.7	0.8	-0.5	0.1	0.5	0.6	0.1
Illnesses of father: High blood pressure	2.1	2.6	5.4	-2.3	-0.8	-1.3	-0.8	-0.8	2.3	-1.3	-1.8	-1.8	-1.8
Alcohol drinker status: Never	1.8	2.1	7.4	1.9	0.7	-0.4	1.0	2.7	-0.0	0.8	0.4	-2.7	-0.3
Ever smoked	0.2	0.4	1.4	0.1	0.9	0.2	1.2	0.7	0.2	0.8	-1.0	0.1	-0.1
Basal metabolic rate	0.1	0.7	3.3	0.5	-0.0	-0.5	-0.3	1.8	0.4	0.5	-1.6	-0.2	-0.2
Leg fat percentage (left)	0.6	2.0	6.2	1.6	-1.2	1.3	0.9	2.5	-2.1	0.8	0.1	-1.6	-0.0
Arm fat-free mass (left)	0.1	0.7	2.7	0.6	0.3	-0.5	-0.6	1.6	0.7	0.5	-1.6	-0.1	-0.1
Number of operations (self-reported)	0.5	0.7	1.7	-0.0	-1.1	-1.2	-0.5	-1.0	-1.0	0.7	-1.3	0.6	0.2
Average weekly beer plus cider intake	0.3	0.5	2.7	-0.6	-0.1	0.1	0.3	0.4	0.4	-0.4	0.4	-1.6	-0.9
Irritability	0.9	1.5	4.3	0.6	0.5	-1.4	-2.1	-0.5	0.1	-1.6	-0.9	-1.8	-1.0
Risk taking	0.9	1.3	8.0	0.2	1.8	0.3	0.0	0.2	2.8	0.8	0.7	0.4	0.6
Ever had prostate specific antigen (PSA) test	0.4	0.4	2.3	0.5	-0.7	-1.5	-0.7	-0.4	-0.6	0.1	-0.1	-0.2	0.5
Fractured/broken bones in last 5 years	0.2	0.3	0.6	-0.7	-0.3	0.0	0.6	-0.8	0.2	-0.7	0.8	-0.2	-0.1
Age started oral contraceptive pill	0.3	0.4	2.1	0.1	-0.1	-1.5	-0.6	-0.9	0.4	-0.2	0.1	0.6	0.7
Diastolic blood pressure, automated reading	0.4	1.1	5.3	0.4	1.3	0.3	1.2	0.4	-0.2	0.9	2.3	-1.1	0.3
Ever depressed for a whole week	1.3	1.6	5.0	2.2	-0.5	0.5	-0.3	-0.1	-0.8	1.7	0.8	1.3	2.1
Unable to work because of sickness or disability	1.1	1.4	3.5	0.1	0.8	-0.8	1.0	-0.6	1.6	1.5	1.0	1.9	1.5
Commuting to job workplace: Cycle	2.8	3.4	9.2	-1.7	0.9	-1.3	-2.3	-2.1	2.5	-3.0	-0.2	-0.3	-1.9
Myopia	0.8	1.1	5.1	-1.0	-1.0	-2.3	-0.7	0.8	0.3	-0.8	-0.4	-0.1	-1.4
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.5	-0.1	-0.6	-1.2	-0.4	-0.6	0.4	0.4	-0.6	1.6	0.9
Cholesterol lowering medication	0.6	0.8	2.2	0.9	-0.0	-1.2	0.4	-0.6	0.6	1.5	-0.1	1.0	1.4
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	7.6	0.2	-0.4	-0.5	2.8	1.1	-1.2	1.0	0.4	0.9	0.3
Pain experienced in last month	0.2	0.4	1.5	-0.7	0.6	1.2	0.7	-0.6	0.1	0.6	0.2	0.1	0.0
Supplements: Calcium	0.4	0.5	2.7	-0.4	1.6	-1.0	-0.2	0.9	0.1	0.1	0.4	-0.3	-0.1
Basal cell carcinoma (self-reported)	2.2	2.7	6.4	-1.0	-2.5	-0.7	1.3	1.6	-1.7	-1.6	-1.7	-0.8	-2.3
Heart attack/myocardial infarction (self-reported)	1.1	1.5	3.3	0.5	0.2	0.1	-1.6	1.2	0.7	-1.6	-1.0	-1.8	-1.7
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	4.8	-1.5	-0.4	0.3	0.4	-1.4	-0.4	-1.2	0.0	2.2	0.1
Heart disease (siblings)	0.7	0.9	3.9	-0.9	-2.0	1.1	0.5	-0.8	0.2	0.1	-0.4	1.4	0.0
Alcohol drinker status: Previous	1.5	1.7	5.5	1.2	0.6	1.8	1.1	2.3	0.1	2.0	-0.1	-1.2	0.2
Pack years of smoking	0.2	0.3	1.6	-0.3	0.6	-0.7	-1.3	-0.4	-0.0	-0.3	-0.1	-0.4	-0.4
Impedance of whole body	0.2	1.3	3.6	-1.4	-0.6	1.9	1.7	-1.1	-1.4	-0.6	0.2	0.3	-0.3
Leg fat mass (left)	0.3	1.2	5.2	1.3	-0.4	0.7	0.7	2.3	-1.5	0.6	-0.4	-1.2	-0.1
Arm predicted mass (left)	0.1	0.7	2.9	0.9	0.1	-0.4	-0.4	1.7	0.3	0.8	-1.6	0.0	0.3