Hub : Genes

SOCS1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 TCGA Kidney Renal Clear Cell Carcinoma 0.0843 0.0393 0.0011 0.011 0.026 0.034 NA 0.020 0.016 0.00051 8.4e-05 NA 0.002
2 TCGA Testicular Germ Cell Tumors 0.0960 0.0530 0.0073 0.019 0.015 -0.005 NA 0.017 0.069 0.09100 5.6e-01 NA 0.078

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 1.7 2.7 4.0 -1.2 2.0
Bipolar Disorder or Schizophrenia 0.7 1.7 2.6 -1.6 0.9
Depressed Affect (Nagel 2018) 0.8 1.7 2.5 -1.0 1.6
Depression (Nagel 2018) 0.5 0.8 1.1 -1.0 -0.7
Intelligence (Savage-Jansen 2018) 0.7 2.2 4.4 -0.3 2.1
Neuroticism (Nagel 2018) 1.1 2.6 3.4 -1.4 1.8
Schizophrenia (2018) 0.4 0.7 1.3 -1.1 -0.4
Schizophrenia vs Biploar Disorder 1.2 1.6 2.8 0.6 -1.7
Worry (Nagel 2018) 0.3 0.6 1.0 -1.0 0.5
Alzheimer’s Disease (in mother) 1.3 1.5 2.2 0.9 -1.5
Alzheimer’s Disease (in father) 1.0 1.1 1.6 -0.8 1.3
Alzheimer’s Disease (including proxy) 0.4 0.7 0.9 0.7 -0.9
Crohns Disease (2017) 0.4 0.8 1.7 -1.3 -0.2
Irritable Bowel Disease (IBD) 0.6 1.3 2.3 -0.6 -1.5
Ulcerative Colitis (UC) 0.4 0.7 1.4 -0.1 -1.2
Major Depression (MDD) 0.0 0.0 0.1 0.0 -0.3
Reaction Time 0.8 1.4 2.8 -0.2 -1.7
Verbal and Numeric Reasoning (VNR) 1.3 3.1 5.2 1.0 2.3
Breast Cancer 0.5 1.3 2.2 0.7 1.5
Ovarian Cancer 0.5 0.7 1.2 -0.3 -1.1
Prostate Cancer 1.4 2.0 3.5 0.7 -1.9
Age at First Birth 0.3 0.5 0.9 -0.1 1.0
Bipolar Disorder (2011) 1.0 1.0 1.6 -0.6 1.3
Body Mass Index (BMI) (2010) 0.1 0.1 0.1 0.2 0.3
Coronary Artery Disease (CAD) 0.3 0.4 0.6 -0.3 0.8
Crohns Disease (2012) 0.6 1.0 1.9 -1.4 -0.2
Mean Putamen Volume 1.7 2.0 3.9 0.2 2.0
Fasting Glucose 0.6 0.7 1.2 -1.1 -0.3
HbA1C 4.6 5.2 10.1 3.2 0.4
HDL Cholesterol 0.6 1.0 1.9 1.4 0.2
LDL Cholesterol 2.6 4.2 7.7 0.8 2.8
Lupus 0.1 0.2 0.2 0.4 -0.4
Neuroticism (2016) 2.6 3.8 5.5 -2.3 1.5
Primary Biliary Cirrhosis 5.2 7.4 13.0 -3.6 -1.3
Rheumatoid Arthritis 2.1 2.9 4.2 -2.1 1.2
Schizophrenia (2014) 0.8 1.8 2.6 -1.6 1.0
Triglycerides 0.7 1.1 2.2 -0.1 1.5
Type 2 Diabetes (T2D) (2012) 0.1 0.1 0.2 0.2 0.4
Ulcerative Colitis 0.9 1.3 2.5 -0.4 -1.6
Blood Eosinophil Count 16.2 124.7 139.2 10.5 -11.8
Blood Platelet Count 1.6 19.0 37.5 6.1 -0.7
Blood Red Count 0.6 5.5 9.3 1.3 -3.0
Blood White Count 0.9 7.0 8.1 2.4 -2.9
Heel T-Score 0.2 1.5 3.0 -0.0 1.7
BMI 0.0 0.2 0.4 0.6 -0.3
Height 0.1 2.1 3.8 -0.6 -1.9
Waist Hip Ratio (WHR) 0.2 1.1 1.3 -1.2 0.9
Systolic Blood Pressure 0.5 2.5 5.0 -0.1 2.2
Smoking Status 0.8 2.0 2.4 1.3 -1.5
Allergy or Eczema 4.6 12.1 12.7 3.4 -3.6
Cardiovascular Disease 0.4 1.3 1.7 1.0 1.3
Hypothyroidism (self reported) 1.7 3.9 4.5 -1.8 2.1
Respiratory disease 3.8 8.4 11.9 2.2 -3.4
Type 2 Diabetes (T2D) (2018) 0.2 0.4 0.6 -0.7 0.5
Lung FEV1/FVC ratio 0.2 1.0 1.8 0.5 1.3
Lung FVC 1.0 5.2 7.8 -2.8 1.6
Neuroticism 0.6 1.4 1.6 -1.1 1.3
Chronotype (morning person) 0.4 0.9 1.5 -0.4 1.2
Hair Pigment 0.1 2.1 3.2 -1.8 1.0
Tanning 0.2 2.0 3.4 1.8 -0.7
Hand grip strength (left) 0.6 1.5 1.8 1.1 1.3
Number of treatments/medications taken 0.3 0.5 0.7 -0.8 -0.6
Average weekly spirits intake 0.6 0.8 1.1 -0.7 1.0
Sensitivity / hurt feelings 0.3 0.5 1.0 0.2 1.0
Frequency of depressed mood in last 2 weeks 0.9 1.3 1.7 -0.9 -1.3
Hearing difficulty/problems: Yes 0.7 1.1 1.7 0.7 -1.3
Relative age of first facial hair 0.5 1.1 1.9 -0.5 -1.4
Other serious medical condition/disability diagnosed by doctor 1.5 1.9 3.6 -1.9 -0.5
Ever used hormone-replacement therapy (HRT) 2.7 3.5 6.5 -2.5 -0.6
Ever had hysterectomy (womb removed) 0.4 0.4 0.9 -0.9 0.2
Systolic blood pressure, automated reading 0.6 1.7 3.0 -0.6 1.7
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 0.9 -1.0 -0.5
Angina 2.2 2.9 3.6 -1.9 1.5
Medication for hormone replacement therapy 1.8 2.0 3.5 -1.9 -0.7
Vitamin and mineral supplements 0.3 0.3 0.6 -0.8 0.3
Supplements: Zinc 1.4 1.5 3.1 0.1 -1.8
Medication: Co-codamol 0.2 0.2 0.3 -0.4 0.5
Medication: Metformin 0.2 0.2 0.5 -0.2 0.7
Diabetes (father) 0.2 0.2 0.4 -0.0 -0.7
Diabetes (mother) 0.6 0.7 1.5 1.2 -0.0
Severe depression (siblings) 0.3 0.4 0.5 0.5 -0.7
Pack years adult smoking proportion 0.3 0.5 0.9 0.4 0.9
Impedance of leg (right) 1.0 5.0 8.7 -3.0 1.2
Leg fat-free mass (left) 0.3 1.4 2.5 1.6 0.6
Trunk fat percentage 0.8 3.3 4.4 -2.1 1.5
Hand grip strength (right) 0.8 2.1 4.2 -0.1 2.1
Townsend deprivation index at recruitment 0.6 0.8 1.3 0.6 -1.1
Current tobacco smoking 2.0 3.3 3.7 1.9 -1.7
Average weekly fortified wine intake 0.6 0.7 1.4 -0.1 1.2
Maternal smoking around birth 0.0 0.0 0.0 -0.0 -0.1
Fed-up feelings 0.5 1.0 1.0 -1.0 1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 0.8 -0.9 -0.3
Relative age voice broke 0.2 0.2 0.5 -0.1 -0.7
Taking other prescription medications 0.5 0.7 1.2 -1.1 0.5
Age when periods started (menarche) 0.3 0.7 1.0 0.6 1.0
Bilateral oophorectomy (both ovaries removed) 3.5 4.1 8.1 -2.9 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 2.3 0.3 1.5
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 1.0 -0.2 1.0
Qualifications: CSEs or equivalent 1.5 1.9 2.9 1.0 -1.7
Serious illness, injury or assault to yourself 0.5 0.6 1.1 -1.1 0.0
High blood pressure 0.1 0.4 0.5 -0.4 0.7
Hayfever, allergic rhinitis or eczema 3.7 8.0 10.6 2.3 -3.2
Multivitamins +/- minerals 0.9 1.1 1.8 1.3 -0.7
Stomach or abdominal pain in last month 0.6 0.8 1.5 -1.2 0.1
Supplements: Glucosamine 1.6 2.1 3.2 1.8 -1.0
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 1.0 -1.0 -0.2
Medication: Atenolol 0.2 0.2 0.4 -0.6 0.1
Medication: Levothyroxine sodium 1.0 1.7 2.9 -1.7 0.7
Sitting height 0.8 5.7 9.4 -3.1 1.4
Chronic bronchitis/emphysema (father) 0.1 0.1 0.1 -0.3 -0.3
High blood pressure (mother) 0.3 0.4 0.6 0.4 -0.8
Body mass index (BMI) 0.0 0.2 0.2 -0.4 0.4
Impedance of leg (left) 1.0 5.0 8.4 -2.9 1.2
Leg predicted mass (left) 0.3 1.6 2.8 1.7 0.7
Trunk fat mass 0.5 2.0 2.0 -1.4 1.4
Waist circumference 0.7 2.5 3.0 -1.4 1.7
Number of incorrect matches in round 0.0 0.0 0.1 -0.3 -0.2
Past tobacco smoking 0.1 0.3 0.5 0.7 -0.0
Alcohol usually taken with meals 1.4 2.2 2.6 -1.4 1.6
Nervous feelings 0.3 0.5 0.9 -0.9 0.3
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 0.8 -0.2 -0.9
Hearing difficulty/problems with background noise 0.8 1.2 1.6 0.9 -1.3
Hair/balding pattern: Pattern 2 0.4 0.5 0.7 -0.6 -0.8
Had menopause 0.1 0.1 0.1 -0.4 0.0
Had other major operations 0.2 0.3 0.6 0.8 0.0
Forced vital capacity (FVC) 0.7 2.7 3.6 -1.9 1.3
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 1.9 0.4 1.4
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 0.9 -0.3 1.0
Qualifications: None of the above 0.6 1.3 2.4 0.5 -1.5
Financial difficulties in last 2 years 0.0 0.0 0.0 0.1 -0.0
Mouth/teeth dental problems 2.4 3.7 7.3 2.7 -0.2
Heart attack 0.5 0.7 1.3 0.1 1.1
Allergy 5.8 13.2 15.5 -3.3 3.9
Pain all over the body in last month 3.2 3.4 5.2 -2.3 1.3
Diabetes (self-reported) 0.0 0.0 0.0 0.2 -0.1
Hayfever/allergic rhinitis (self-reported) 3.6 4.8 6.2 2.5 -1.8
Medication: Ramipril 2.4 3.1 6.1 -0.4 2.5
Medication: Simvastatin 0.0 0.0 0.0 -0.2 0.0
Fluid intelligence score 0.7 1.5 2.0 1.0 1.4
Illnesses of siblings 0.3 0.4 0.6 0.4 -0.8
Neuroticism score 0.9 1.8 2.1 -1.2 1.5
Weight 0.1 0.4 0.7 -0.3 0.8
Impedance of arm (right) 0.3 1.6 2.8 -1.7 0.6
Arm fat percentage (right) 0.4 1.5 2.2 -1.5 0.9
Trunk fat-free mass 0.3 1.6 2.9 1.7 0.6
Hip circumference 0.3 1.5 1.5 -1.2 1.2
Time employed in main current job 1.1 1.2 1.5 1.0 -1.2
Alcohol intake versus 10 years previously 0.4 0.7 1.3 1.1 0.2
Father’s age at death 0.8 1.1 2.1 -1.4 0.2
Worrier / anxious feelings 1.3 2.4 4.4 -2.1 0.6
Frequency of tiredness / lethargy in last 2 weeks 1.1 1.9 2.4 -1.2 1.5
Falls in the last year 0.6 0.8 1.2 -0.6 -1.1
Hair/balding pattern: Pattern 3 0.1 0.2 0.4 0.6 -0.3
Number of live births 0.3 0.5 0.5 0.7 0.7
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 1.5 -1.2 1.2
Pulse rate 1.6 2.8 4.5 1.0 2.1
Happiness 0.2 0.3 0.3 0.5 0.5
Noisy workplace 1.6 1.9 2.6 1.1 -1.6
Qualifications: A levels/AS levels or equivalent 0.6 1.3 2.5 0.4 1.6
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.3 0.5 -0.7 0.2
Mouth/teeth dental problems: Dentures 3.4 5.8 10.6 -3.3 1.0
Asthma 3.8 7.5 9.9 2.3 -3.1
Medication: Ibuprofen (e.g. Nurofen) 1.1 1.4 2.3 -0.7 1.5
Medication: Cholesterol lowering 2.5 3.9 6.4 -2.5 1.1
Depression (self-reported) 0.2 0.2 0.3 -0.5 -0.3
Medication: Lansoprazole 0.6 0.7 1.2 -0.5 1.1
Prospective memory result 0.5 0.6 1.0 -0.4 -1.0
Lung cancer (father) 0.2 0.2 0.3 -0.5 0.4
Illnesses of mother 0.3 0.3 0.3 -0.6 0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.2 1.7 -1.3 0.8
Pulse wave Arterial Stiffness index 0.4 0.4 0.8 -0.3 0.9
Impedance of arm (left) 0.5 2.2 3.6 -1.9 0.9
Arm fat mass (right) 0.2 0.8 0.9 -0.8 1.0
Trunk predicted mass 0.3 1.7 3.1 1.8 0.6
Standing height 0.0 0.4 0.7 0.4 0.8
Length of working week for main job 0.2 0.3 0.5 0.2 -0.7
Exposure to tobacco smoke at home 0.9 1.0 1.1 0.9 1.1
Breastfed as a baby 0.4 0.5 0.9 1.0 0.1
Tense / ‘highly strung’ 1.0 1.7 2.0 -1.4 1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.2 2.4 -1.5 0.1
Hair/balding pattern: Pattern 4 0.1 0.3 0.4 -0.3 0.7
Birth weight of first child 0.2 0.3 0.6 0.1 0.8
Peak expiratory flow (PEF) 2.5 5.7 9.3 -1.4 3.0
Pulse wave reflection index 0.5 0.6 0.8 -0.7 -0.9
Ever highly irritable/argumentative for 2 days 0.2 0.3 0.3 0.5 -0.5
Loud music exposure frequency 1.9 2.0 2.1 1.4 -1.5
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 1.5 1.2 -0.0
Mouth/teeth dental problems: Bleeding gums 1.7 2.2 2.5 -1.6 1.4
Blood clot in the leg (DVT) 0.6 0.8 1.5 -0.3 1.2
Medication: Paracetamol 0.8 1.3 2.6 -0.3 -1.6
Headache pain in last month 0.6 1.0 1.2 1.1 -0.9
Medication for cholesterol, blood pressure or diabetes 3.7 6.2 7.2 2.7 -2.3
Glaucoma (self-reported) 0.8 1.0 1.9 0.2 1.4
Gout (self-reported) 0.1 0.1 0.1 0.3 -0.2
Hypothyroidism/myxoedema (self-reported) 0.9 1.8 3.0 -1.7 0.8
Medication: Amlodipine 0.6 0.8 0.9 -0.8 1.0
Medication: Ventolin 100micrograms inhaler 5.0 6.4 9.9 1.7 -3.1
Birth weight 0.2 0.4 0.7 0.1 0.8
Chronic bronchitis/emphysema (mother) 0.1 0.1 0.1 0.3 -0.2
High blood pressure (siblings) 0.4 0.6 0.8 -0.9 0.6
Forced vital capacity (FVC), Best measure 0.5 1.7 3.0 -1.7 0.6
Body fat percentage 1.1 4.2 5.8 -2.4 1.6
Leg fat percentage (right) 1.4 5.1 7.6 -2.8 1.6
Arm fat-free mass (right) 0.2 1.0 1.0 1.0 1.0
Exposure to tobacco smoke outside home 0.6 0.8 1.5 0.3 -1.2
Comparative body size at age 10 0.6 1.7 2.0 1.4 -1.1
Number of full brothers 0.1 0.1 0.1 0.2 0.4
Worry too long after embarrassment 3.0 5.1 6.3 -2.5 2.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 0.8 -0.9 0.5
Wheeze or whistling in the chest in last year 4.4 7.8 10.8 2.2 -3.3
Number of children fathered 4.2 4.7 7.4 1.4 -2.7
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.2 -0.5 -0.4
Age at first live birth 0.3 0.5 1.1 0.0 1.0
Pulse wave peak to peak time 0.4 0.4 0.8 0.3 -0.9
Health satisfaction 0.1 0.1 0.2 -0.5 -0.1
Shortness of breath walking on level ground 0.9 1.0 1.6 -1.3 0.7
Qualifications: College or University degree 0.1 0.3 0.5 -0.2 0.7
Eye problems/disorders: None of the above 0.2 0.3 0.6 0.8 -0.0
Mouth/teeth dental problems: Loose teeth 0.3 0.4 0.7 -0.9 0.0
Emphysema/chronic bronchitis 0.2 0.3 0.5 0.7 -0.2
Medication for pain relief, constipation, heartburn 0.6 1.0 2.0 1.4 -0.0
Neck or shoulder pain in last month 1.0 1.5 2.9 0.3 -1.7
Medication: Blood pressure 1.9 3.3 4.0 -2.0 1.6
Angina (self-reported) 1.5 2.0 2.9 -1.7 1.1
Migraine (self-reported) 0.2 0.2 0.3 0.3 0.6
Medication: Ibuprofen 0.6 0.7 0.8 -0.7 0.9
Medication: Allopurinol 0.0 0.0 0.0 0.0 0.1
Medication: Omeprazole 1.5 1.8 3.6 -1.9 0.2
Medication: Seretide 50 evohaler 1.6 1.9 3.3 -0.7 -1.8
Mean time to correctly identify matches 1.1 2.1 2.5 -1.3 -1.6
Heart disease (mother) 1.4 1.7 1.7 -1.3 1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.0 0.0 0.0 0.2 -0.1
Whole body fat mass 0.4 1.9 2.0 -1.3 1.4
Leg fat mass (right) 0.6 2.3 2.6 -1.6 1.4
Arm predicted mass (right) 0.3 1.3 1.7 1.3 1.0
Pulse rate, automated reading 1.0 3.2 5.8 0.8 2.4
Alcohol intake frequency. 0.0 0.1 0.2 -0.0 -0.4
Comparative height size at age 10 0.1 0.7 1.3 0.4 1.1
Number of full sisters 0.2 0.2 0.3 -0.2 0.6
Suffer from ‘nerves’ 1.6 2.6 4.0 -2.0 1.0
Overall health rating 0.3 0.7 0.8 -0.7 0.9
Chest pain or discomfort 0.1 0.2 0.3 0.3 -0.6
Had major operations 0.4 0.5 1.0 -1.0 -0.2
Age at last live birth 2.9 4.2 8.0 0.5 2.8
Family relationship satisfaction 1.1 1.4 2.7 -0.1 1.7
Leg pain on walking 0.9 1.1 1.2 1.0 -1.1
Qualifications: NVQ or HND or HNC or equivalent 0.1 0.1 0.1 0.2 0.3
Commuting to job workplace: Car/motor vehicle 1.9 2.1 2.5 1.6 -1.3
Illness, injury, bereavement, stress in last 2 years 0.0 0.1 0.1 -0.2 -0.3
Medication: Aspirin 0.2 0.3 0.5 -0.7 0.4
Supplements: Vitamin C 0.3 0.4 0.7 -0.3 0.8
Knee pain experienced in last month 0.9 1.4 2.8 1.7 -0.2
Hypertension (Self-reported) 0.2 0.5 0.7 -0.6 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 1.3 -1.1 0.4
Illnesses of father: Heart disease 0.9 1.3 2.4 -0.3 -1.6
Illnesses of siblings: Diabetes 2.6 3.2 3.5 1.9 -1.7
Smoking status: Previous 0.6 0.8 1.0 -1.0 0.8
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 1.1 1.0 1.1
Whole body fat-free mass 0.3 1.7 3.0 1.7 0.6
Leg fat-free mass (right) 0.3 1.8 3.4 1.9 0.5
Arm fat percentage (left) 0.5 1.9 2.6 -1.6 1.1
Average weekly red wine intake 0.8 1.1 2.2 -0.2 1.5
Handedness (chirality/laterality): Left-handed 1.2 1.4 2.7 -0.2 -1.7
Mood swings 1.1 2.0 3.9 0.0 2.0
Loneliness, isolation 0.5 0.7 1.3 -1.1 -0.0
Long-standing illness, disability or infirmity 0.8 1.1 1.3 -1.0 1.2
Ever had bowel cancer screening 3.8 4.5 7.7 -2.8 1.1
Diabetes diagnosed by doctor 0.0 0.0 0.1 -0.3 0.1
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.2 -0.1 -0.4
Friendships satisfaction 0.9 1.2 2.3 1.5 -0.2
Qualifications: nursing, teaching 2.1 3.2 6.4 0.1 2.5
Commuting to job workplace: Walk 0.2 0.2 0.5 0.7 0.2
Eye problems/disorders: Cataract 1.2 1.4 2.7 -0.4 -1.6
Mouth/teeth dental problems: Mouth ulcers 1.7 2.8 5.1 0.7 -2.3
Medication for cholesterol 0.3 0.4 0.7 0.8 0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.1 1.3 2.1 0.6 -1.5
Back pain experienced in last month 1.1 1.6 2.8 -0.5 1.7
Mineral and other dietary supplements 0.7 0.9 1.4 -1.2 0.6
Breast cancer (self-reported) 1.7 2.0 3.6 1.9 0.7
Asthma (self-reported) 3.8 7.6 9.9 2.3 -3.1
Osteoporosis (self-reported) 0.4 0.6 0.7 -0.6 0.8
Osteoarthritis (self-reported) 0.4 0.5 0.7 0.9 -0.6
Medication: Aspirin 0.4 0.5 0.7 -0.9 0.6
Medication: Gliclazide 0.7 0.8 1.5 -1.2 -0.3
Illnesses of father: None of the above (group 1) 1.4 1.7 2.5 -1.0 1.6
Smoking status: Current 2.0 3.1 3.3 1.7 -1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.0 4.2 8.2 -2.9 0.4
Whole body water mass 0.3 1.7 3.1 1.8 0.6
Leg predicted mass (right) 0.4 1.9 3.5 1.9 0.6
Arm fat mass (left) 0.2 0.8 0.8 -0.9 0.9
Number of self-reported non-cancer illnesses 0.1 0.1 0.2 0.3 0.4
Average weekly champagne plus white wine intake 7.0 9.6 17.5 -4.2 1.3
Miserableness 0.5 0.8 1.4 -0.4 1.2
Guilty feelings 0.6 0.9 1.0 -0.9 1.0
Wears glasses or contact lenses 0.4 0.5 0.8 -0.9 0.5
Ever taken oral contraceptive pill 1.0 1.1 2.0 -0.5 1.4
Hearing aid user 0.6 0.7 1.1 -1.0 -0.6
Mother’s age at death 0.0 0.0 0.0 0.1 -0.2
Financial situation satisfaction 0.0 0.0 0.1 0.2 0.1
Tinnitus: Yes, now most or all of the time 1.0 1.1 1.5 1.2 -0.8
Commuting to job workplace: Public transport 0.2 0.2 0.4 0.7 -0.0
Eye problems/disorders: Glaucoma 0.8 1.0 1.6 0.6 1.3
Medication: Blood pressure 0.0 0.0 0.0 0.1 -0.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.0 0.9 1.0
Supplements: Fish oil (including cod liver oil) 0.6 0.8 1.2 0.6 -1.1
High cholesterol (Self-reported) 1.3 2.4 3.2 1.2 1.8
Medication: Bendroflumethiazide 0.4 0.6 1.2 0.2 -1.1
Medication: Paracetamol 0.7 1.1 2.0 -0.3 -1.4
Medication: Lisinopril 0.1 0.1 0.2 0.4 -0.2
Medication: Atorvastatin 1.4 1.8 3.4 -0.3 1.9
Illnesses of father: High blood pressure 0.6 0.8 1.3 0.4 -1.2
Alcohol drinker status: Never 1.9 2.3 2.5 -1.5 1.6
Ever smoked 0.0 0.0 0.0 0.1 -0.0
Basal metabolic rate 0.2 1.1 1.7 1.3 0.7
Leg fat percentage (left) 1.2 4.4 6.5 -2.5 1.5
Arm fat-free mass (left) 0.1 0.5 0.8 0.9 0.4
Number of operations (self-reported) 0.1 0.2 0.3 0.1 -0.6
Average weekly beer plus cider intake 2.2 3.1 6.2 2.5 0.1
Irritability 1.4 2.3 2.6 -1.6 1.4
Risk taking 0.1 0.2 0.4 -0.7 0.1
Ever had prostate specific antigen (PSA) test 2.2 2.5 4.7 -2.2 0.5
Fractured/broken bones in last 5 years 0.7 0.9 1.8 1.3 -0.2
Age started oral contraceptive pill 1.6 2.1 3.0 -1.7 1.1
Diastolic blood pressure, automated reading 0.8 2.5 2.7 1.5 1.6
Ever depressed for a whole week 0.2 0.3 0.5 -0.3 0.7
Unable to work because of sickness or disability 1.3 1.6 2.4 -1.0 1.5
Commuting to job workplace: Cycle 1.2 1.5 1.5 -1.2 1.2
Myopia 0.4 0.6 1.2 -0.2 1.1
Vascular/heart problems diagnosed by doctor 0.3 0.7 1.0 0.6 -1.0
Cholesterol lowering medication 0.3 0.4 0.6 0.4 0.8
Medication: Omeprazole (e.g. Zanprol) 2.2 2.7 5.2 -2.3 0.5
Pain experienced in last month 1.0 1.6 2.5 -1.6 0.9
Supplements: Calcium 0.1 0.1 0.2 0.4 -0.2
Basal cell carcinoma (self-reported) 3.3 3.9 6.4 1.2 -2.5
Heart attack/myocardial infarction (self-reported) 0.6 0.8 1.5 0.2 1.2
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 0.7 -0.5 0.8
Heart disease (siblings) 0.4 0.4 0.5 -0.6 -0.7
Alcohol drinker status: Previous 0.7 0.8 0.8 -0.9 0.9
Pack years of smoking 0.4 0.6 1.1 0.0 1.1
Impedance of whole body 0.8 3.9 6.4 -2.5 1.2
Leg fat mass (left) 0.5 1.8 1.8 -1.3 1.3
Arm predicted mass (left) 0.2 0.8 1.4 1.2 0.4