TWAS hub - SPATA6L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellum	0.4070	0.1350	5.8e-03	0.010	NA	0.082	NA	0.085	1.6e-01	NA	2.1e-03	NA	1.7e-03
2	GTEx	Breast Mammary Tissue	0.2980	0.0730	2.5e-04	0.126	NA	0.096	NA	0.147	5.5e-07	NA	1.3e-05	NA	5.7e-08
3	GTEx	Breast Mammary Tissue (Female)	0.3108	0.1240	1.5e-02	0.065	NA	0.044	NA	0.068	5.2e-03	NA	1.9e-02	NA	4.4e-03
4	GTEx	Colon Transverse	0.4400	0.0770	1.7e-07	0.246	NA	0.228	NA	0.264	4.6e-12	NA	3.5e-11	NA	6.4e-13
5	GTEx	Esophagus Mucosa	0.2410	0.0550	5.5e-06	0.256	NA	0.265	NA	0.273	3.4e-17	NA	8.0e-18	NA	2.0e-18
6	GTEx	Skin Not Sun Exposed Suprapubic	0.3670	0.0670	3.9e-07	0.337	NA	0.340	NA	0.339	3.8e-19	NA	2.4e-19	NA	2.6e-19
7	GTEx	Skin Sun Exposed Lower leg	0.5140	0.0510	0.0e+00	0.361	NA	0.381	NA	0.419	3.7e-31	NA	3.2e-33	NA	2.1e-37
8	GTEx	Testis	0.3440	0.0910	1.1e-03	0.033	NA	0.054	NA	0.070	1.3e-02	NA	2.0e-03	NA	5.0e-04
9	GTEx	Thyroid	0.3700	0.0580	1.7e-09	0.311	NA	0.331	NA	0.315	2.9e-24	NA	5.5e-26	NA	1.4e-24
10	METSIM	Adipose	0.0974	0.0283	1.7e-04	-0.001	0.018	0.008	0.018	0.000	4.0e-01	0.00072	2.2e-02	0.00082	2.7e-01
11	ROSMAP	Brain Pre-frontal Cortex	0.0825	0.0258	8.1e-04	0.002	0.018	0.012	0.018	0.007	1.8e-01	0.00210	9.1e-03	0.00210	3.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Blood Red Count	6.5	62.7	102.0	7.0	8.8	8.4	8.8	8.0	10.1	9.0	1.8	9.7	4.7	6.9
Pain all over the body in last month	3.6	3.9	7.3	2.1	2.2	2.2	2.7	2.5	1.8	2.2	0.9	1.8	1.5	1.1
Long-standing illness, disability or infirmity	3.3	5.0	9.3	1.9	2.7	2.3	2.9	2.6	2.1	3.1	1.4	2.7	0.6	0.9
Commuting to job workplace: Walk	3.2	3.5	5.5	1.4	2.2	1.9	2.1	2.2	2.1	2.3	0.9	2.0	-0.9	1.7
Blood Platelet Count	3.0	35.2	169.0	-4.0	0.8	0.1	2.6	-1.4	7.5	2.7	-1.0	6.4	9.3	13.0
Body Mass Index (BMI) (2010)	2.9	4.0	7.4	2.5	2.3	2.4	2.7	2.5	2.0	2.0	-0.6	1.9	0.2	0.3
Medication: Co-codamol	2.8	3.2	6.6	1.2	2.1	1.6	2.6	1.9	2.3	2.3	1.1	2.0	0.0	1.2
Number of self-reported non-cancer illnesses	2.8	4.9	6.9	1.7	2.5	2.4	2.6	2.4	2.6	2.6	1.0	2.0	1.6	2.1
Medication: Lisinopril	2.8	3.7	5.4	2.1	2.0	2.1	1.9	1.9	2.3	2.2	0.9	2.3	1.2	1.4
Heel bone mineral density (BMD) T-score, automated (left)	2.6	6.0	10.1	2.4	2.7	2.0	2.4	2.3	3.1	2.8	0.7	3.2	2.0	2.4
Falls in the last year	2.6	3.5	6.0	2.1	2.2	1.3	2.5	1.8	2.3	2.2	-0.9	2.4	1.0	0.4
Medication: Ventolin 100micrograms inhaler	2.5	3.1	6.3	-0.2	1.9	1.3	2.4	1.6	1.9	2.0	1.4	2.5	1.7	1.5
Reaction Time	2.4	4.7	8.8	3.0	2.5	1.8	2.2	2.4	2.6	2.8	1.1	2.3	0.7	0.9
Illness, injury, bereavement, stress in last 2 years	2.4	2.9	5.5	-1.5	-1.9	-1.8	-2.3	-1.8	-2.3	-2.1	-0.4	-2.0	0.1	-0.2
Average weekly champagne plus white wine intake	2.4	3.3	5.9	2.0	2.0	2.0	2.0	2.2	1.8	1.7	2.4	1.5	0.6	0.9
Mean time to correctly identify matches	2.3	4.3	8.7	3.0	2.4	1.9	2.2	2.4	2.5	2.6	0.5	2.0	1.0	-0.0
Alzheimer’s Disease (including proxy)	2.2	3.3	6.3	1.2	2.0	1.6	2.0	1.8	2.3	2.5	1.9	2.0	0.7	1.0
Worry too long after embarrassment	2.2	3.7	7.7	0.5	1.9	1.2	1.7	1.5	2.2	2.3	0.6	2.3	-2.6	2.8
Unable to work because of sickness or disability	2.2	2.8	7.9	1.5	1.5	1.2	1.6	1.4	1.5	2.2	2.8	1.9	1.4	0.5
Bipolar Disorder (2018)	2.1	3.3	13.1	2.1	1.4	0.9	1.0	1.2	2.0	2.1	3.6	1.4	1.2	1.4
Hand grip strength (right)	2.1	5.8	14.6	-0.8	-2.1	-1.0	-2.2	-1.4	-3.4	-2.8	0.6	-3.8	-3.8	-1.5
Headache pain in last month	2.1	3.7	10.3	1.6	1.9	1.5	1.9	1.6	2.6	2.1	0.6	2.0	0.2	3.2
Depression (Nagel 2018)	2.0	3.0	6.2	1.3	1.9	1.7	2.2	1.7	2.1	1.7	-1.5	2.5	-0.7	0.8
Waist Hip Ratio (WHR)	2.0	9.2	16.1	2.2	3.5	3.3	3.7	3.0	3.8	3.4	-1.0	4.0	1.4	2.1
Hand grip strength (left)	2.0	5.4	11.8	-2.1	-2.2	-1.3	-2.3	-1.7	-3.4	-2.9	0.9	-3.4	-2.6	-0.8
Ever used hormone-replacement therapy (HRT)	2.0	2.5	7.3	-0.9	-1.4	-1.3	-0.9	-1.2	-1.3	-1.5	-0.4	-1.7	-2.6	-2.7
Number of full sisters	2.0	2.5	6.8	0.5	1.4	1.2	1.3	1.1	2.0	1.8	2.6	1.7	-0.6	1.8
Breast Cancer	1.9	4.7	8.0	-1.4	-2.8	-2.8	-2.2	-2.8	-2.5	-2.4	1.4	-2.3	0.4	-1.2
Nervous feelings	1.9	3.5	6.9	1.0	2.1	2.0	2.2	1.8	2.3	2.2	-0.2	2.6	-1.2	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.4	4.4	0.6	1.9	1.8	1.6	1.7	2.1	1.7	0.6	1.7	1.2	1.5
Loneliness, isolation	1.9	2.7	4.1	-0.9	-2.0	-1.9	-1.7	-1.9	-1.9	-1.8	-1.0	-1.8	-1.5	-0.9
Chronic bronchitis/emphysema (father)	1.8	2.1	3.8	-0.1	-1.4	-1.2	-1.7	-1.4	-1.8	-1.6	-1.5	-1.3	1.3	-1.9
Had other major operations	1.8	2.2	5.5	0.6	2.0	2.3	1.8	2.1	1.2	1.6	-0.0	1.4	0.8	0.2
Eye problems/disorders: None of the above	1.8	2.1	4.4	-0.7	-1.6	-2.1	-1.8	-1.8	-1.2	-1.7	-0.1	-1.0	-1.8	-0.8
Mouth/teeth dental problems: Loose teeth	1.8	2.1	3.9	1.5	1.6	1.5	1.5	1.4	1.6	2.0	1.5	1.2	-1.0	0.7
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	8.9	1.6	1.4	1.1	1.1	1.8	0.3	1.7	3.0	0.5	0.9	1.0
Taking other prescription medications	1.6	2.5	5.3	1.8	1.8	1.6	2.3	1.7	1.8	2.0	0.6	1.3	0.5	0.7
Waist circumference	1.6	5.9	11.0	1.7	2.6	1.6	2.6	2.1	3.1	3.2	2.0	3.3	-0.0	2.5
Loud music exposure frequency	1.6	1.8	3.2	-1.8	-1.6	-1.5	-1.3	-1.5	-1.6	-1.4	0.8	-1.3	-0.6	0.8
Fractured/broken bones in last 5 years	1.6	2.0	6.5	2.1	1.3	1.4	1.3	1.5	0.5	1.5	2.5	0.9	0.1	-0.9
Basal cell carcinoma (self-reported)	1.6	1.9	3.3	-1.4	-1.7	-1.8	-1.3	-1.7	-1.3	-1.5	0.4	-1.4	-1.5	-0.3
Health satisfaction	1.5	1.9	5.2	-2.3	-1.4	-0.9	-1.4	-1.1	-1.8	-1.1	0.0	-1.8	0.4	-1.5
Medication for cholesterol	1.5	2.2	5.2	-1.4	-1.6	-1.4	-2.3	-1.4	-1.7	-1.6	-0.9	-1.7	1.3	0.4
Medication: Aspirin	1.5	1.9	7.9	0.8	1.2	1.7	1.0	1.5	0.5	1.6	2.8	-0.1	-0.6	1.2
Bipolar Disorder or Schizophrenia	1.4	3.4	7.4	2.7	1.9	1.5	1.3	1.8	1.8	2.1	2.1	1.9	1.4	1.1
Heel T-Score	1.4	10.9	23.8	1.3	3.6	3.2	4.2	3.4	4.1	3.7	1.1	4.9	1.5	2.7
Current tobacco smoking	1.4	2.2	4.9	1.9	1.3	1.0	1.6	1.0	2.2	1.6	-0.2	2.0	1.5	1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.2	6.6	1.5	2.0	1.5	2.1	1.7	2.1	2.3	1.1	2.6	0.8	1.0
Medication: Ramipril	1.4	1.8	5.2	2.2	1.2	1.1	0.8	1.4	0.5	1.2	2.3	0.8	-0.4	1.4
Lung cancer (father)	1.4	1.7	3.3	-0.9	-1.8	-1.6	-1.8	-1.8	-1.1	-1.2	0.3	-1.1	1.1	-0.2
Handedness (chirality/laterality): Left-handed	1.4	1.6	3.8	-0.4	-1.7	-2.0	-1.3	-1.9	-1.5	-1.1	0.8	-1.1	-0.3	0.4
Osteoporosis (self-reported)	1.4	1.7	6.2	-0.9	-1.2	-0.7	-1.1	-0.9	-2.0	-0.9	0.6	-1.5	-0.9	-2.5
Pain experienced in last month	1.4	2.4	4.9	0.1	-1.6	-1.6	-2.2	-1.6	-1.5	-1.8	-0.4	-1.7	-2.0	-1.1
High blood pressure (mother)	1.3	1.8	5.2	0.3	1.4	1.2	0.9	1.2	1.8	1.3	-1.0	1.3	2.3	1.0
Had menopause	1.3	1.6	4.8	-0.4	-0.8	-0.6	-0.8	-0.6	-1.4	-1.1	-2.0	-1.2	-1.2	-2.2
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	5.7	-2.4	-0.9	-0.8	-0.8	-1.0	-1.4	-1.1	-2.0	-0.9	-0.5	-1.1
Glaucoma (self-reported)	1.3	1.5	2.4	1.3	1.5	1.4	1.5	1.5	1.2	1.1	-0.8	1.6	1.0	-0.1
High blood pressure (siblings)	1.3	1.9	4.4	0.5	1.5	1.7	1.6	1.7	0.8	1.1	-1.6	0.7	2.1	-0.6
Exposure to tobacco smoke outside home	1.3	1.7	4.2	0.7	1.1	0.7	1.0	1.0	1.6	1.4	1.1	1.9	0.6	2.1
Suffer from ‘nerves’	1.3	2.0	3.8	0.7	1.7	1.4	1.3	1.3	1.8	1.8	0.2	1.9	-0.1	2.0
Smoking status: Previous	1.3	1.9	7.3	-1.2	-0.8	-0.5	-1.0	-0.7	-1.8	-1.3	-1.4	-1.7	-0.3	-2.7
Heart attack	1.2	1.6	2.2	-0.5	1.3	1.5	1.4	1.3	0.9	1.3	1.5	1.4	1.0	1.4
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.1	0.8	1.4	1.4	1.8	1.4	1.6	1.3	-0.5	0.9	-0.6	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	2.5	-1.6	-1.5	-1.0	-1.5	-1.5	-1.1	-1.3	0.9	-0.8	-0.7	-0.9
Friendships satisfaction	1.2	1.4	4.4	-1.4	-1.2	-1.1	-1.4	-1.1	-1.2	-0.9	0.1	-1.0	-2.1	-0.7
Commuting to job workplace: Public transport	1.2	1.5	3.2	0.8	1.0	1.1	1.4	1.3	0.9	1.3	1.7	0.8	0.8	1.8
Eye problems/disorders: Glaucoma	1.2	1.4	2.3	1.3	1.4	1.5	1.5	1.5	1.0	1.1	-0.7	1.3	0.6	0.3
Alzheimer’s Disease (in mother)	1.1	1.3	2.8	0.1	1.2	1.0	1.6	1.2	1.1	1.7	1.6	1.1	-0.4	0.0
Mean Putamen Volume	1.1	1.3	2.2	1.5	1.2	1.3	1.1	1.3	1.1	1.2	0.4	1.2	0.6	0.8
HDL Cholesterol	1.1	1.8	2.9	-1.0	-1.4	-1.6	-1.2	-1.5	-1.4	-1.2	1.1	-0.9	-1.7	-1.7
Serious illness, injury or assault to yourself	1.1	1.4	2.6	0.3	1.5	1.6	1.5	1.5	1.0	1.4	0.3	1.3	1.0	-0.4
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.8	3.5	-0.9	1.3	1.2	1.7	1.1	1.8	1.8	-0.1	1.9	0.8	0.9
Illnesses of mother	1.1	1.4	5.7	0.2	-0.8	-0.8	-0.5	-0.7	-1.0	-0.4	2.4	-1.0	-1.8	1.5
Tense / ‘highly strung’	1.1	1.8	3.3	-0.2	-1.7	-1.8	-1.5	-1.8	-1.5	-1.3	-0.1	-1.4	-1.1	-1.1
Medication: Blood pressure	1.1	2.0	6.9	2.6	1.2	1.1	0.8	1.4	1.1	1.0	0.8	0.6	2.2	1.4
Leg fat mass (right)	1.1	4.1	8.8	0.9	2.1	1.2	1.9	1.7	2.6	2.7	2.3	3.0	-0.0	2.1
Supplements: Calcium	1.1	1.2	2.5	-1.6	-1.0	-0.5	-1.0	-0.8	-1.3	-1.2	1.4	-1.5	0.5	-0.5
Ulcerative Colitis	1.0	1.4	4.6	2.1	1.1	1.5	1.1	1.4	0.9	1.1	0.7	0.7	-0.4	-1.1
Leg fat-free mass (left)	1.0	5.4	8.4	1.6	2.6	1.8	2.1	2.2	2.8	2.9	2.1	2.7	-1.0	2.9
Leg predicted mass (left)	1.0	5.5	8.7	1.6	2.6	1.9	2.2	2.3	2.8	2.9	2.0	2.8	-0.8	2.9
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	3.2	-1.2	-1.1	-1.3	-0.7	-1.3	-1.0	-0.8	-0.0	-0.9	-1.8	-0.9
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	2.8	1.7	1.1	1.5	1.4	1.4	0.7	1.0	-1.3	0.6	0.5	-0.1
Weight	1.0	4.9	8.7	1.5	2.2	1.3	2.0	1.8	2.7	2.9	2.5	2.8	-0.6	3.0
Exposure to tobacco smoke at home	1.0	1.1	3.4	-0.3	0.5	0.1	1.1	0.1	1.3	1.1	1.2	1.4	0.4	1.9
Neck or shoulder pain in last month	1.0	1.4	2.8	0.6	1.4	1.4	1.6	1.0	1.3	1.6	-0.1	1.7	-0.3	0.0
Overall health rating	1.0	2.2	3.9	1.2	1.8	2.0	2.0	2.0	1.2	1.8	-0.6	1.5	0.3	-1.1
Medication: Aspirin	1.0	1.4	6.6	0.6	1.0	1.3	0.7	1.2	0.3	1.3	2.6	-0.1	-0.3	1.3
Financial situation satisfaction	1.0	1.2	9.5	-3.1	-0.7	-0.3	-0.9	-0.6	-0.7	-0.5	-0.7	-0.5	-0.1	-0.9
Basal metabolic rate	1.0	5.4	8.4	1.7	2.5	1.8	2.2	2.3	2.5	2.9	2.6	2.5	-1.0	2.8
Coronary Artery Disease (CAD)	0.9	1.1	4.8	-1.1	-0.6	-1.0	-1.2	-1.1	-0.7	-0.8	-1.0	-0.5	2.2	-0.3
Schizophrenia (2014)	0.9	2.1	4.7	2.2	1.7	1.2	0.8	1.6	1.3	1.9	1.2	1.7	0.5	1.2
Cardiovascular Disease	0.9	2.9	4.5	2.1	2.0	1.6	2.0	1.8	1.9	2.1	0.5	2.1	0.5	0.9
Average weekly fortified wine intake	0.9	1.1	2.6	-0.7	-1.2	-1.6	-0.9	-1.2	-0.6	-1.3	-1.1	-0.9	-0.8	-0.7
Hayfever, allergic rhinitis or eczema	0.9	1.9	2.8	1.4	1.6	1.2	1.6	1.5	1.4	1.7	0.5	1.2	-0.9	1.7
Medication: Simvastatin	0.9	1.4	8.5	1.2	0.6	0.3	0.5	0.6	0.2	0.9	2.9	0.1	-1.6	0.9
Trunk fat-free mass	0.9	5.0	7.8	1.9	2.5	1.9	2.1	2.4	2.1	2.7	2.8	2.0	-1.3	2.6
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	3.3	0.1	1.3	1.5	1.8	1.3	1.1	1.6	0.6	1.3	1.0	0.6
Trunk predicted mass	0.9	5.1	7.6	1.9	2.5	2.0	2.2	2.5	2.1	2.7	2.8	2.0	-1.2	2.5
Hair/balding pattern: Pattern 4	0.9	2.3	4.8	1.1	1.8	2.1	2.2	1.9	1.6	1.8	-0.4	1.0	0.6	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	2.6	-0.2	-1.2	-0.9	-1.3	-1.0	-1.2	-1.3	-0.5	-1.6	-0.5	-0.8
Medication: Ibuprofen	0.9	1.0	3.4	-1.8	-0.5	-0.5	-0.3	-0.5	-1.0	-0.6	-1.8	-0.7	-1.0	-0.9
Age at last live birth	0.9	1.3	2.8	-0.1	1.5	1.6	1.5	1.7	0.6	1.1	-0.8	1.1	-0.7	0.3
Commuting to job workplace: Car/motor vehicle	0.9	1.0	3.3	-0.2	-1.0	-1.0	-1.0	-0.9	-1.0	-1.2	-0.1	-1.3	0.5	-1.8
Whole body fat-free mass	0.9	5.1	7.5	1.8	2.5	1.9	2.1	2.3	2.3	2.7	2.6	2.2	-1.3	2.7
Whole body water mass	0.9	4.9	7.2	1.7	2.5	1.9	2.1	2.4	2.2	2.7	2.5	2.1	-1.3	2.5
Medication: Bendroflumethiazide	0.9	1.4	5.0	2.2	1.0	0.4	1.3	1.0	1.2	0.6	-1.2	1.2	0.4	-1.1
Heart attack/myocardial infarction (self-reported)	0.9	1.1	2.1	-0.6	1.1	1.4	1.1	1.1	0.6	1.0	1.4	1.2	1.0	0.9
Leg fat mass (left)	0.9	3.5	7.3	0.9	1.9	1.1	1.7	1.6	2.3	2.5	2.3	2.7	-0.1	1.9
Primary Biliary Cirrhosis	0.8	1.1	2.9	-0.8	1.0	1.0	0.5	1.1	0.7	1.1	-0.1	1.0	1.7	1.5
Neuroticism	0.8	2.0	4.1	-0.0	1.6	1.7	2.0	1.4	1.9	1.8	-1.1	1.6	-0.2	0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.0	2.5	0.2	1.0	0.8	1.2	0.6	1.5	0.9	-0.7	1.6	-0.9	1.0
Medication: Levothyroxine sodium	0.8	1.3	4.2	-0.5	-0.9	-1.1	-0.9	-1.0	-0.8	-0.6	1.9	-1.2	0.4	2.0
Financial difficulties in last 2 years	0.8	1.1	1.7	0.4	1.0	1.1	1.2	0.9	1.0	1.3	1.0	1.2	-0.7	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	2.1	-1.4	1.1	1.3	1.2	1.0	1.0	1.3	0.9	0.9	-1.4	0.3
Birth weight of first child	0.8	1.5	3.2	0.3	-1.4	-1.0	-1.8	-1.2	-1.7	-1.5	0.2	-1.5	-1.0	-0.5
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	5.3	-2.3	-0.6	-0.5	-0.4	-0.9	-0.4	-0.7	-1.4	-0.1	-1.9	-1.4
Leg fat percentage (right)	0.8	2.7	6.8	0.4	1.7	1.0	1.6	1.4	2.1	2.2	1.9	2.6	0.2	1.4
Chest pain or discomfort	0.8	1.1	2.8	0.6	1.2	1.2	1.7	1.3	0.8	1.2	-0.2	1.1	1.1	0.1
Leg fat-free mass (right)	0.8	4.0	6.9	1.4	2.3	1.5	1.7	1.9	2.4	2.5	1.9	2.3	-0.8	2.6
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	3.2	-1.6	-1.3	-1.7	-1.2	-1.8	-0.0	-0.6	-1.1	-0.3	-0.2	-1.1
Breast cancer (self-reported)	0.8	0.9	2.2	-0.1	1.0	1.4	1.2	0.9	1.1	0.9	-0.4	0.7	-0.2	1.5
Osteoarthritis (self-reported)	0.8	1.0	2.1	0.2	1.2	0.8	1.5	1.1	1.1	1.2	-1.0	1.3	0.4	-0.2
Smoking status: Current	0.8	1.3	3.5	1.5	0.9	0.5	1.1	0.6	1.9	1.1	-0.2	1.6	0.9	0.9
Leg predicted mass (right)	0.8	4.0	6.7	1.4	2.3	1.5	1.8	1.9	2.4	2.5	1.9	2.2	-0.8	2.6
Arm fat mass (left)	0.8	3.1	6.0	0.8	1.7	0.9	1.4	1.3	2.2	2.4	2.1	2.4	0.2	2.2
Arm predicted mass (left)	0.8	4.2	8.0	1.7	2.2	1.8	2.1	2.2	1.9	2.5	2.8	1.9	-1.1	1.9
Worry (Nagel 2018)	0.7	1.6	3.3	0.1	1.5	1.4	1.4	1.2	1.5	1.6	-0.6	1.8	-0.9	0.5
LDL Cholesterol	0.7	1.1	6.1	2.5	0.5	0.9	0.5	0.8	0.6	0.7	1.2	0.4	0.7	0.9
Rheumatoid Arthritis	0.7	0.9	1.3	-1.1	-1.0	-0.6	-1.0	-1.1	-1.0	-1.2	-0.9	-0.8	0.5	-1.1
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.9	1.6	0.0	-0.4	0.3	-0.0	0.5	0.3	1.5	-0.4	-1.7	0.1
Blood White Count	0.7	5.4	11.7	2.1	2.5	2.2	2.8	2.3	3.4	3.0	1.1	2.4	-1.1	1.2
Chronotype (morning person)	0.7	1.7	2.6	0.1	-1.5	-1.5	-1.3	-1.5	-1.1	-1.5	1.2	-1.4	-1.6	0.8
Number of treatments/medications taken	0.7	1.3	2.3	1.3	1.3	1.1	1.5	1.4	0.7	1.4	0.7	0.6	0.8	1.2
Supplements: Zinc	0.7	0.8	1.6	0.2	0.9	0.4	1.3	0.7	1.3	0.8	-0.4	1.0	1.1	1.0
Diabetes (mother)	0.7	0.9	1.3	1.1	0.9	1.2	1.1	0.7	1.0	0.9	-1.1	1.0	0.4	-0.5
Trunk fat mass	0.7	2.9	6.0	0.9	1.5	0.5	1.3	1.0	2.2	2.3	2.1	2.4	-0.3	2.3
Hearing difficulty/problems with background noise	0.7	1.2	3.1	-0.3	-1.1	-0.9	-0.9	-1.2	-0.9	-0.9	-1.4	-0.9	-1.0	-1.8
Mouth/teeth dental problems	0.7	1.1	3.8	-1.7	0.8	1.3	0.6	1.3	-0.1	0.4	2.0	-0.2	-0.1	1.0
Diabetes (self-reported)	0.7	1.1	10.0	0.1	0.4	0.3	0.5	0.3	-0.1	0.7	3.2	0.0	0.5	0.7
Pulse rate	0.7	1.3	3.2	1.8	0.9	0.4	1.6	0.8	1.2	1.3	1.3	0.9	0.2	1.0
Medication: Cholesterol lowering	0.7	1.1	3.2	1.6	-0.4	-0.4	-0.8	-0.1	-1.0	-0.2	1.7	-1.1	1.8	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	5.5	0.9	1.7	2.3	1.3	1.8	0.9	1.1	0.3	0.9	-2.4	1.2
Arm fat mass (right)	0.7	2.8	5.5	0.6	1.6	0.9	1.3	1.2	2.1	2.3	2.0	2.3	0.1	2.1
Breastfed as a baby	0.7	0.9	2.2	0.9	-1.0	-0.9	-1.1	-0.9	-1.1	-0.7	1.2	-1.5	-0.4	-0.2
Qualifications: College or University degree	0.7	2.3	4.8	-0.1	1.8	2.1	2.2	2.0	1.2	1.3	0.3	1.9	-0.7	1.3
Illnesses of father: High blood pressure	0.7	0.8	1.7	-1.1	-0.6	-0.5	-1.2	-0.6	-1.3	-1.1	-0.8	-1.1	-0.1	-0.8
Arm fat-free mass (left)	0.7	3.5	7.3	1.5	2.0	1.5	1.9	1.9	1.7	2.2	2.7	1.7	-1.1	1.9
Age started oral contraceptive pill	0.7	0.9	2.2	-0.9	-0.8	-0.7	-0.7	-0.8	-0.7	-1.0	-1.4	-0.5	-0.8	-1.5
Schizophrenia (2018)	0.6	1.2	3.3	1.8	1.2	1.2	0.8	1.3	0.8	1.0	-0.3	1.3	0.8	0.2
Crohns Disease (2017)	0.6	1.4	4.4	-1.1	-1.3	-1.2	-0.9	-1.0	-1.1	-1.3	0.6	-2.1	-1.1	-0.5
Ulcerative Colitis (UC)	0.6	1.2	7.0	0.9	0.4	1.2	1.2	0.8	0.2	0.5	-0.2	-0.2	-1.2	-2.6
Bipolar Disorder (2011)	0.6	0.5	1.6	1.1	0.0	0.0	1.0	0.0	0.7	0.7	1.3	0.4	0.9	-0.2
HbA1C	0.6	0.6	2.2	-0.1	-0.6	-1.0	0.1	-0.8	-0.2	-0.3	1.5	-0.1	1.5	0.5
Hypothyroidism (self reported)	0.6	1.5	10.0	0.8	0.5	0.1	0.0	0.4	0.4	0.7	1.8	-0.3	1.0	3.2
Hearing difficulty/problems: Yes	0.6	0.9	2.5	0.8	1.0	0.8	1.0	0.4	1.6	1.0	-0.6	1.6	0.5	0.4
Multivitamins +/- minerals	0.6	0.7	2.5	-0.0	1.0	0.3	0.6	0.5	1.1	1.2	0.5	0.9	0.3	1.6
Hair/balding pattern: Pattern 2	0.6	0.7	1.8	-1.0	-1.0	-1.4	-1.1	-1.2	-0.6	-0.7	-0.8	-0.4	-0.1	0.2
Illnesses of siblings	0.6	0.9	1.9	-0.4	-1.1	-1.2	-1.2	-1.4	-0.4	-1.0	0.7	-0.3	-1.1	1.0
Arm fat percentage (right)	0.6	2.5	5.3	0.4	1.5	0.7	1.4	1.1	2.1	2.2	1.7	2.3	0.7	1.7
Father’s age at death	0.6	0.8	3.5	-0.4	0.7	0.6	0.4	0.7	0.4	0.8	1.9	0.9	-0.8	1.1
Depression (self-reported)	0.6	0.7	3.7	-1.1	-0.9	-0.5	-0.2	-0.9	-0.4	-0.5	0.1	-0.6	0.3	-1.9
Length of working week for main job	0.6	0.6	1.4	-0.8	0.9	1.0	1.2	1.0	0.4	0.9	0.8	0.4	-0.0	0.5
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	6.7	0.2	-0.4	-0.6	-0.4	-0.5	-0.2	-0.0	2.0	-0.8	0.7	2.6
Arm fat-free mass (right)	0.6	3.2	5.2	1.4	1.9	1.6	1.6	1.9	1.5	2.0	2.3	1.6	-1.7	1.8
Whole body fat mass	0.6	2.7	6.0	0.8	1.4	0.5	1.3	1.0	2.1	2.2	2.0	2.4	-0.0	2.0
Arm predicted mass (right)	0.6	2.9	5.0	1.2	1.8	1.4	1.5	1.7	1.5	2.0	2.2	1.5	-1.7	1.9
Knee pain experienced in last month	0.6	1.0	2.9	-1.1	-1.0	-0.9	-0.8	-0.8	-1.3	-0.4	-0.1	-1.0	0.6	-1.7
Hypertension (Self-reported)	0.6	1.7	2.7	1.6	1.4	1.2	1.4	1.4	1.6	1.1	-0.7	1.4	1.6	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.8	-0.9	0.8	0.2	1.0	0.7	1.0	1.0	-0.1	1.0	0.3	1.3
Illnesses of father: Heart disease	0.6	0.8	2.6	-0.7	-0.1	0.3	-0.2	0.3	-1.3	-0.7	-1.1	-1.2	-1.0	-1.6
Qualifications: nursing, teaching	0.6	0.9	4.9	0.2	0.5	0.5	0.5	0.7	-0.5	0.4	1.6	0.1	-2.2	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.7	0.3	-1.0	-0.6	-0.8	-0.9	-1.0	-0.9	-0.5	-1.3	-0.6	-0.7
Medication: Paracetamol	0.6	1.0	2.3	1.5	1.0	0.6	1.0	0.9	1.0	0.7	-1.5	1.3	-0.2	-0.2
Myopia	0.6	0.9	5.4	0.3	-0.3	-0.5	-0.5	-0.3	0.1	-0.0	0.6	-0.2	-2.3	-1.8
Cholesterol lowering medication	0.6	0.9	2.8	0.5	0.7	0.8	1.4	0.9	0.2	0.8	1.7	0.2	-1.2	-0.9
Alzheimer’s Disease (in father)	0.5	0.6	2.0	0.5	0.3	-0.1	0.4	0.1	1.1	0.7	0.6	0.7	1.4	1.1
Major Depression (MDD)	0.5	0.6	3.4	0.4	0.1	0.3	0.6	0.6	-1.0	-0.1	0.3	-0.5	-1.9	-0.9
Systolic Blood Pressure	0.5	2.4	6.1	2.5	1.4	1.9	1.4	1.6	1.7	1.2	1.3	1.4	-0.5	1.6
Frequency of depressed mood in last 2 weeks	0.5	0.8	2.1	0.4	0.9	0.8	1.4	0.7	0.9	1.2	0.3	1.2	-0.7	0.3
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	3.6	-1.9	0.1	0.5	0.0	0.4	-0.7	-0.2	0.6	-0.9	-0.5	-0.5
Medication: Metformin	0.5	0.7	5.2	0.3	0.5	0.1	0.8	0.3	0.4	1.1	2.3	0.5	0.2	-0.3
Pack years adult smoking proportion	0.5	0.7	1.7	0.8	0.8	0.7	0.8	0.7	1.3	1.2	0.9	0.9	0.7	0.6
Relative age voice broke	0.5	0.8	1.9	-0.1	-1.0	-0.8	-0.9	-1.0	-1.2	-1.0	-0.7	-0.7	1.4	-0.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.7	-1.0	-0.9	-1.3	-0.4	-1.2	-0.2	-0.6	0.6	-0.2	-0.3	0.3
Qualifications: CSEs or equivalent	0.5	0.7	4.4	-1.1	-0.4	-0.3	-0.7	-0.6	-0.6	0.2	2.1	-0.2	-0.4	0.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	2.3	0.8	-0.1	0.2	0.4	-0.0	0.2	-0.3	-1.5	-0.3	-0.5	-1.5
Past tobacco smoking	0.5	0.8	4.5	0.6	0.4	0.1	0.7	0.3	1.2	0.8	0.7	1.1	-0.0	2.1
Hip circumference	0.5	2.2	4.8	1.0	1.3	0.4	1.0	1.0	1.6	1.8	2.2	1.6	-1.0	2.2
Hair/balding pattern: Pattern 3	0.5	0.8	4.3	0.3	0.5	1.2	1.1	0.9	-0.4	0.2	0.4	-0.3	-0.5	-2.1
Pulse wave Arterial Stiffness index	0.5	0.6	1.5	0.9	0.6	0.2	0.7	0.3	1.2	1.0	0.6	1.0	0.6	0.6
Standing height	0.5	4.8	11.3	3.0	2.0	1.2	2.1	1.6	2.5	2.2	1.9	2.1	-1.1	3.4
Peak expiratory flow (PEF)	0.5	1.1	8.6	0.5	-0.1	0.1	-0.2	-0.1	-0.9	0.0	0.9	-0.9	-2.9	0.7
Pulse wave peak to peak time	0.5	0.5	1.3	-0.8	-0.7	-0.5	-0.7	-0.5	-1.1	-1.0	-0.6	-0.9	-0.5	-0.4
Shortness of breath walking on level ground	0.5	0.6	2.9	-1.7	-0.6	-0.5	0.1	-0.7	-0.1	-0.3	0.3	-0.4	0.4	-1.4
Medication: Seretide 50 evohaler	0.5	0.5	3.5	-1.9	-0.3	-0.3	0.1	-0.3	-0.3	0.0	0.1	0.4	0.4	-1.4
Comparative height size at age 10	0.5	2.5	8.0	2.8	1.5	1.4	1.5	1.6	1.2	1.5	1.1	1.1	-1.9	0.8
Leg pain on walking	0.5	0.6	2.6	-1.6	-0.7	-0.6	-0.7	-0.9	-0.9	-0.3	0.3	-0.2	0.3	-0.7
Illnesses of siblings: Diabetes	0.5	0.6	1.7	1.2	0.5	0.4	0.4	0.8	-0.9	0.6	1.2	-0.4	1.3	0.0
Arm fat percentage (left)	0.5	1.9	4.7	0.2	1.2	0.5	1.1	0.8	1.9	2.0	1.5	2.2	0.3	1.7
Ever had bowel cancer screening	0.5	0.6	1.3	-1.1	-0.3	-0.3	-0.5	-0.1	-0.7	-0.6	-0.9	-0.8	0.8	-1.1
Diabetes diagnosed by doctor	0.5	0.9	9.0	-0.2	-0.2	-0.2	0.1	-0.3	-0.4	0.3	3.0	-0.2	0.3	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.0	1.0	0.4	0.3	1.0	0.4	0.5	0.6	-0.8	0.7	-0.4	-1.0
Eye problems/disorders: Cataract	0.5	0.5	2.7	-1.2	-0.2	0.1	-0.4	-0.2	-0.3	-0.2	-0.5	-0.6	1.6	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.2	3.4	0.8	1.3	1.8	0.8	1.4	0.0	0.8	-0.6	0.5	-1.8	-0.2
Ever taken oral contraceptive pill	0.5	0.6	3.1	-0.5	-0.2	-0.4	0.3	-0.3	0.1	0.4	1.8	-0.0	0.1	1.5
Medication: Blood pressure	0.5	1.0	2.0	0.8	0.9	0.9	1.2	0.8	1.2	0.8	-1.0	1.4	-0.3	-1.0
Leg fat percentage (left)	0.5	1.8	4.5	0.3	1.3	0.7	1.2	1.1	1.6	1.9	1.8	2.1	0.2	1.0
Vascular/heart problems diagnosed by doctor	0.5	1.3	2.2	-1.5	-1.3	-1.2	-1.4	-1.4	-1.3	-1.1	0.1	-1.1	-1.0	0.0
Neuroticism (Nagel 2018)	0.4	1.0	3.1	-0.3	0.9	0.8	1.1	0.8	0.9	1.0	-1.2	1.2	-1.8	0.2
Irritable Bowel Disease (IBD)	0.4	0.9	4.7	0.1	-0.3	0.4	0.3	0.2	-0.5	-0.4	0.1	-1.4	-1.4	-2.2
Prostate Cancer	0.4	0.6	1.5	0.9	-0.3	-0.5	-0.7	-0.0	-1.1	-0.5	1.2	-1.2	-0.0	0.5
BMI	0.4	2.2	4.8	1.1	1.9	1.3	1.7	1.7	1.7	2.2	0.6	1.7	0.0	1.0
Diabetes (father)	0.4	0.5	1.4	1.0	0.5	1.0	1.0	0.5	0.3	0.4	1.2	0.5	0.0	-0.3
Maternal smoking around birth	0.4	0.6	3.5	-1.0	-0.5	-0.3	-0.5	-0.6	-0.5	-0.3	0.4	-0.1	1.0	-1.9
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.3	1.5	0.7	0.4	0.7	0.9	0.5	0.5	0.2	0.0	0.4	0.6
High blood pressure	0.4	1.2	1.9	1.4	1.1	1.0	1.2	1.2	1.3	0.8	-0.7	1.2	1.2	-0.2
Sitting height	0.4	2.7	8.2	1.7	1.6	0.9	2.0	1.4	2.0	1.4	1.0	1.2	-0.9	2.9
Body mass index (BMI)	0.4	1.9	4.0	0.1	1.4	0.8	1.1	1.2	1.6	2.0	1.8	1.9	-0.1	1.6
Alcohol usually taken with meals	0.4	0.6	4.1	1.0	-0.5	-0.6	-0.1	-0.3	-0.3	-0.5	0.8	-0.6	-2.0	-0.4
Qualifications: None of the above	0.4	0.8	4.8	0.2	-0.5	-0.8	0.0	-0.8	1.0	-0.0	-1.0	0.3	2.2	-0.7
Neuroticism score	0.4	0.8	1.5	-0.3	0.8	0.5	1.0	0.4	1.2	1.2	-0.7	1.1	-1.1	0.8
Time employed in main current job	0.4	0.5	1.7	0.0	-0.7	-0.7	-0.7	-0.5	-1.0	-0.4	0.1	-1.3	-0.5	-0.6
Alcohol intake versus 10 years previously	0.4	0.6	1.4	0.0	1.1	1.1	0.7	1.2	0.4	1.1	0.1	0.4	0.7	-0.3
Qualifications: A levels/AS levels or equivalent	0.4	0.9	4.6	-1.4	-0.5	-0.1	-0.3	-0.4	-1.1	-0.5	0.7	-0.7	-2.1	0.6
Mouth/teeth dental problems: Dentures	0.4	0.7	5.1	2.3	0.4	-0.2	0.4	0.4	0.6	0.4	-1.2	0.4	0.1	0.5
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.0	-0.4	-0.9	-1.0	-0.8	-0.9	-0.5	-0.8	-0.7	-0.6	0.4	-0.5
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.6	-0.9	-0.4	-0.0	-0.4	0.1	-1.6	-0.5	0.8	-1.4	-0.6	0.5
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.0	1.0	-0.3	-0.1	0.0	-0.8	0.9	-0.0	-0.6	1.0	0.4	-1.0
Medication: Paracetamol	0.4	0.7	2.6	1.6	0.7	0.3	0.6	0.5	0.8	0.5	-1.2	1.0	0.5	-0.1
Forced vital capacity (FVC), Best measure	0.4	1.6	3.9	1.4	1.4	2.0	1.3	1.6	0.6	0.6	-0.0	0.7	-2.0	0.4
Body fat percentage	0.4	1.5	4.0	0.4	0.9	0.1	0.8	0.5	1.6	1.7	1.6	2.0	0.1	1.5
Number of full brothers	0.4	0.5	3.0	-0.1	0.3	0.6	0.3	0.7	-0.1	0.1	-0.1	-0.5	-0.9	-1.7
Number of children fathered	0.4	0.5	1.8	-1.1	-0.4	-0.3	-0.2	-0.3	-0.4	-0.9	-1.3	-0.5	0.1	-0.7
Age at first live birth	0.4	0.8	3.2	-0.1	-0.5	-0.0	-0.7	-0.3	-1.5	-1.0	-1.8	-1.0	-0.5	-0.5
Emphysema/chronic bronchitis	0.4	0.5	2.6	-0.9	0.1	-0.2	-0.3	-0.0	0.5	-0.1	-1.6	-0.0	0.6	1.0
Medication: Omeprazole	0.4	0.4	1.0	-0.0	0.5	0.1	1.0	0.4	1.0	0.8	0.2	0.6	0.5	1.0
Heart disease (mother)	0.4	0.5	1.4	-0.9	-0.8	-0.3	-0.2	-0.8	-0.1	-0.7	-1.2	-0.5	1.0	-0.3
Had major operations	0.4	0.5	1.8	0.1	-0.7	-0.8	-0.3	-0.9	-0.2	-0.4	0.6	-0.4	-0.9	1.3
Back pain experienced in last month	0.4	0.6	2.8	0.4	0.4	0.3	1.0	0.4	0.0	0.3	-1.3	0.0	1.7	-0.4
Miserableness	0.4	0.7	1.3	-0.9	0.7	0.7	1.1	0.6	1.1	0.8	-0.9	0.6	-1.1	0.3
Alcohol drinker status: Never	0.4	0.4	1.2	0.3	-0.9	-1.1	-0.6	-0.9	-0.4	-0.7	-0.6	-0.5	0.0	-0.3
Number of operations (self-reported)	0.4	0.5	1.1	0.6	0.8	1.0	0.6	0.7	0.6	0.7	0.2	0.7	1.0	0.6
Irritability	0.4	0.7	2.9	-0.5	-0.7	-0.3	-0.0	-0.7	-1.1	-0.7	-0.6	-0.5	-1.1	-1.7
Ever depressed for a whole week	0.4	0.5	1.6	-0.6	-0.6	-0.9	-0.1	-0.7	-0.5	-0.1	0.7	-0.4	-1.3	-0.8
Alcohol drinker status: Previous	0.4	0.4	1.8	-0.9	0.2	-0.3	0.4	-0.1	0.3	0.1	-0.8	0.4	1.3	1.0
Depressed Affect (Nagel 2018)	0.3	0.6	2.9	-0.9	0.3	0.6	0.8	0.5	0.3	0.2	-1.7	0.2	-1.1	-0.2
Ovarian Cancer	0.3	0.4	2.9	1.7	0.5	0.1	-0.0	0.4	0.4	0.8	0.1	0.2	0.6	0.3
Crohns Disease (2012)	0.3	0.4	2.2	0.6	-0.2	-0.0	-0.2	0.1	-0.3	-0.2	1.0	-1.0	-1.5	-0.1
Lupus	0.3	0.5	0.9	0.8	1.0	1.0	0.3	0.9	0.7	0.9	0.1	0.4	0.2	-0.5
Height	0.3	6.4	17.3	4.2	2.5	1.8	3.0	2.2	2.7	2.5	2.6	2.3	1.0	2.0
Smoking Status	0.3	0.7	1.1	0.4	1.0	0.9	1.1	0.9	1.0	0.6	-1.0	0.9	-0.2	0.2
Allergy or Eczema	0.3	0.8	1.9	1.4	1.0	0.7	0.9	1.1	0.7	1.1	0.6	0.5	-0.6	0.7
Respiratory disease	0.3	0.6	2.6	-0.3	0.5	-0.2	1.1	0.1	1.0	0.3	0.4	0.9	-0.3	1.6
Type 2 Diabetes (T2D) (2018)	0.3	0.6	5.2	0.0	-0.1	-0.1	0.3	-0.1	-0.0	0.2	2.3	0.2	0.9	0.6
Lung FVC	0.3	1.5	7.1	0.9	0.4	1.6	0.3	1.0	-1.1	-0.4	-0.8	-1.0	-2.7	-1.5
Sensitivity / hurt feelings	0.3	0.5	3.3	-0.0	0.5	0.7	0.5	0.3	0.8	0.5	0.3	0.6	-1.8	0.4
Ever had hysterectomy (womb removed)	0.3	0.3	1.0	1.0	-0.4	-0.6	-0.0	-0.5	-0.1	-0.2	0.9	-0.1	-0.6	-0.3
Angina	0.3	0.4	1.3	-0.7	-0.2	-0.3	-0.1	0.1	-0.9	-0.1	1.2	-0.9	0.4	0.4
Medication for hormone replacement therapy	0.3	0.3	1.0	0.6	0.4	0.5	0.7	0.5	0.3	0.3	0.7	0.1	-1.0	0.3
Trunk fat percentage	0.3	1.3	3.6	0.3	0.8	-0.0	0.7	0.2	1.6	1.6	1.5	1.9	0.1	1.6
Townsend deprivation index at recruitment	0.3	0.5	1.1	-0.4	-1.0	-1.0	-0.7	-1.0	-0.4	-0.5	0.5	-0.5	-0.2	0.8
Stomach or abdominal pain in last month	0.3	0.3	1.7	0.6	-0.3	-1.0	0.1	-0.5	0.0	-0.3	-0.0	-0.0	1.3	0.4
Number of incorrect matches in round	0.3	0.5	2.8	0.8	0.2	0.1	-0.0	0.1	-0.1	0.1	-0.5	-0.2	-1.3	-1.7
Allergy	0.3	0.6	2.7	-0.4	-0.6	-0.2	-0.8	-0.5	-0.9	-0.5	-0.0	-0.7	0.9	-1.7
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	5.4	0.1	0.5	1.3	0.3	0.8	-0.7	-0.1	-0.7	-0.5	-2.3	0.4
Medication: Lansoprazole	0.3	0.3	1.2	-1.1	0.4	0.2	0.5	0.2	0.8	0.4	0.2	0.8	0.3	0.4
Blood clot in the leg (DVT)	0.3	0.4	1.0	-1.0	-0.4	-0.3	-0.9	-0.6	-0.2	-0.6	-0.7	-0.4	0.9	0.3
Gout (self-reported)	0.3	0.4	1.7	1.2	-0.5	-0.9	-0.0	-0.4	-0.4	-0.4	-0.2	-0.6	0.0	-1.3
Comparative body size at age 10	0.3	0.9	3.3	-0.1	0.6	0.5	0.0	0.7	0.4	0.9	1.6	0.4	-1.8	1.5
Angina (self-reported)	0.3	0.4	1.3	-0.7	-0.3	-0.3	-0.2	0.1	-1.1	-0.2	1.0	-1.1	0.3	0.1
Family relationship satisfaction	0.3	0.3	2.4	-0.2	-0.5	-0.5	-0.2	-0.5	-0.2	-0.1	0.3	-0.3	-1.6	0.2
Average weekly red wine intake	0.3	0.5	2.9	0.3	-0.3	-0.4	0.2	-0.4	0.1	-0.1	1.7	-0.2	0.3	1.5
Mood swings	0.3	0.5	1.5	-0.1	0.7	0.8	1.2	0.8	0.4	1.0	0.2	0.4	-0.6	-0.1
Illnesses of father: None of the above (group 1)	0.3	0.4	2.0	0.4	-0.1	-0.4	-0.0	-0.3	1.0	0.4	0.1	0.5	-1.4	0.7
Wears glasses or contact lenses	0.3	0.4	0.7	-0.2	-0.7	-0.9	-0.9	-0.6	-0.8	-0.6	0.1	-0.8	-0.6	0.0
Hearing aid user	0.3	0.4	1.3	-0.0	-0.6	-0.6	-0.7	-0.6	-0.3	-0.7	0.6	-0.5	0.3	1.1
Mother’s age at death	0.3	0.3	2.0	-0.5	0.2	0.4	-0.1	0.2	-0.0	-0.3	-1.4	-0.0	0.9	-0.7
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.2	-0.1	0.3	-0.1	0.9	0.1	0.0	0.4	1.0	-0.3	-1.1	0.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.2	0.2	-0.4	-1.0	-0.1	-0.4	-0.8	-0.3	0.3	-0.1	-1.1	0.0
Heart disease (siblings)	0.3	0.3	1.5	-0.0	-0.4	-0.4	-0.2	-0.2	-0.5	-0.4	-0.9	-0.7	0.2	-1.2
Pack years of smoking	0.3	0.4	0.9	0.5	0.5	0.6	0.6	0.5	0.9	0.9	0.7	0.5	0.4	0.0
Intelligence (Savage-Jansen 2018)	0.2	0.6	3.1	-0.9	-0.4	-0.5	-1.1	-0.5	-0.5	-0.5	-0.0	-0.5	-0.2	1.8
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.7	-1.3	-0.4	-0.6	-1.0	-0.5	-0.4	-0.8	-0.2	-0.5	-0.5	1.1
Fasting Glucose	0.2	0.3	1.0	-0.1	-0.0	-0.5	-0.4	-0.2	-0.2	0.5	1.0	0.5	-0.7	-0.5
Triglycerides	0.2	0.3	2.9	1.7	-0.1	-0.4	-0.3	-0.2	0.1	0.0	-0.2	0.2	0.2	0.4
Blood Eosinophil Count	0.2	1.6	7.6	-0.1	0.9	1.1	1.0	0.8	1.3	0.6	-1.8	0.7	2.8	-0.2
Lung FEV1/FVC ratio	0.2	1.2	7.3	-1.4	0.3	0.6	0.1	0.4	-0.3	0.4	0.1	-0.7	-2.7	1.7
Average weekly spirits intake	0.2	0.2	1.2	-0.2	-0.1	-0.3	-0.1	0.1	-0.2	-0.3	-1.1	-0.2	0.5	0.6
Systolic blood pressure, automated reading	0.2	0.6	2.0	0.1	0.8	1.4	0.6	1.3	0.3	0.1	-0.8	0.3	-0.5	-0.6
Vitamin and mineral supplements	0.2	0.2	1.1	0.5	-0.0	0.5	0.1	0.3	-0.4	-0.2	0.1	0.1	-0.7	-1.1
Fed-up feelings	0.2	0.4	0.8	-0.8	0.3	0.5	0.7	0.2	0.8	0.7	-0.1	0.2	-0.9	0.7
Age when periods started (menarche)	0.2	0.4	3.5	0.1	0.1	0.1	0.2	0.1	0.0	0.1	0.3	0.3	-1.9	-0.8
Medication: Atenolol	0.2	0.3	0.7	0.7	0.5	-0.2	0.5	0.5	0.1	0.8	0.6	0.2	-0.8	0.5
Forced vital capacity (FVC)	0.2	0.8	4.0	0.8	0.6	1.3	0.4	0.9	-0.6	-0.3	-0.8	-0.4	-2.0	-0.3
Worrier / anxious feelings	0.2	0.4	1.1	-0.4	0.5	0.2	0.5	0.1	0.7	1.0	0.1	1.0	-1.0	0.2
Number of live births	0.2	0.2	1.5	0.3	-0.1	-0.0	-0.1	0.1	0.2	-0.2	-0.8	-0.0	0.7	-1.2
Happiness	0.2	0.2	1.1	-0.8	-0.0	0.5	0.4	0.1	-0.3	0.1	0.5	-0.0	-0.2	-1.0
Noisy workplace	0.2	0.2	0.5	0.2	-0.5	-0.2	-0.5	-0.4	-0.1	-0.4	-0.6	-0.7	0.7	0.2
Asthma	0.2	0.3	1.0	-0.7	0.2	-0.2	0.8	-0.0	0.6	0.0	0.5	1.0	0.4	0.8
Impedance of arm (left)	0.2	0.9	2.6	-0.0	-1.2	-1.2	-0.8	-1.6	-0.1	-1.0	-1.6	-0.2	0.9	0.1
Medication: Amlodipine	0.2	0.2	0.7	-0.4	0.4	0.4	0.8	0.5	0.7	0.1	-0.1	0.5	0.2	0.8
Birth weight	0.2	0.5	2.5	0.8	0.1	0.0	0.2	0.1	0.7	0.2	-1.6	0.3	-0.3	1.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.6	-0.2	0.6	0.4	0.1	0.6	0.3	0.1	-0.8	0.4	-0.2	-0.6
Migraine (self-reported)	0.2	0.2	1.3	-0.6	0.1	0.2	0.1	0.2	0.2	-0.1	1.1	0.3	-0.4	0.4
Medication: Allopurinol	0.2	0.3	1.0	0.6	0.5	0.4	0.5	0.6	0.4	0.7	-0.2	0.1	-0.0	-1.0
Alcohol intake frequency.	0.2	0.4	2.0	-0.0	0.4	-0.1	0.7	0.2	0.7	0.7	-0.5	0.7	-0.3	1.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.6	0.5	-0.3	-0.2	-0.7	-0.3	-0.8	-0.4	0.5	-0.5	0.3	-0.4
Supplements: Vitamin C	0.2	0.3	0.8	0.4	0.1	-0.6	0.6	-0.1	0.7	-0.0	-0.9	0.0	0.1	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	2.5	0.2	0.2	0.3	0.2	0.1	0.6	0.4	0.7	0.5	-0.8	1.6
Mineral and other dietary supplements	0.2	0.3	1.0	-0.3	-0.8	-0.9	-0.3	-1.0	0.1	-0.3	0.1	0.6	-0.4	-0.1
Medication: Gliclazide	0.2	0.2	1.7	-0.2	-0.0	0.1	-0.2	0.1	-0.2	-0.2	-0.2	-0.1	-0.3	-1.3
Guilty feelings	0.2	0.3	1.7	-0.6	-0.2	-0.4	-0.0	-0.3	-0.5	0.2	0.2	-0.4	-1.3	-0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.7	0.1	0.4	-0.3	0.6	0.2	0.4	0.8	0.4	0.7	0.7	0.8
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.8	0.2	0.4	0.7	-0.0	0.6	-0.5	-0.1	-0.2	-0.9	-0.6	-0.6
High cholesterol (Self-reported)	0.2	0.3	0.8	0.8	-0.4	-0.2	0.1	-0.2	-0.9	-0.2	0.5	-0.8	-0.0	-0.9
Medication: Atorvastatin	0.2	0.3	0.6	0.8	0.3	0.7	0.6	0.4	-0.2	0.3	-0.2	-0.5	0.8	-0.5
Risk taking	0.2	0.4	1.9	0.1	-0.0	0.2	0.1	0.2	-0.5	-0.1	1.4	-0.2	1.1	-0.6
Commuting to job workplace: Cycle	0.2	0.2	1.1	-0.3	-0.0	-0.1	-0.2	-0.2	0.2	0.1	-1.0	0.4	-0.5	0.5
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.8	-0.1	0.3	-0.1	0.8	0.1	0.7	0.7	0.6	0.5	0.4	0.9
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.8	-0.9	-0.3	-0.3	-0.8	-0.5	-0.0	-0.5	-0.4	-0.4	0.9	0.6
Impedance of whole body	0.2	1.0	2.7	0.1	-1.3	-1.2	-0.8	-1.6	-0.4	-1.2	-1.3	-0.4	0.6	-0.4
Schizophrenia vs Biploar Disorder	0.1	0.2	1.1	-0.7	-0.1	0.1	-0.3	-0.0	-0.6	-0.0	0.0	-0.1	-1.1	0.0
Age at First Birth	0.1	0.2	1.6	1.3	0.1	0.1	-0.1	0.1	-0.3	0.1	-0.5	-0.3	-0.4	0.1
Neuroticism (2016)	0.1	0.1	0.5	-0.6	-0.1	-0.1	-0.0	-0.1	-0.2	-0.1	0.7	0.1	-0.4	-0.5
Tanning	0.1	0.9	3.1	0.7	0.6	0.8	0.3	0.5	0.6	0.8	1.8	0.3	0.8	1.7
Relative age of first facial hair	0.1	0.3	1.0	0.9	-0.0	0.1	0.4	-0.0	-0.1	-0.3	-1.0	0.2	1.0	-0.1
Severe depression (siblings)	0.1	0.1	0.3	0.6	-0.1	-0.3	-0.1	-0.3	0.1	0.1	0.6	0.3	0.4	0.2
Supplements: Glucosamine	0.1	0.1	0.7	-0.2	0.0	-0.4	-0.4	0.1	-0.3	-0.2	-0.9	-0.5	-0.4	0.2
Impedance of leg (left)	0.1	0.5	1.1	0.1	-1.0	-0.8	-0.5	-1.0	-0.7	-1.0	-0.5	-0.4	0.8	-0.8
Fluid intelligence score	0.1	0.3	1.0	-0.7	-0.2	-0.2	-1.0	-0.2	-0.3	-0.6	-0.5	-0.2	-0.4	0.6
Impedance of arm (right)	0.1	0.5	1.9	0.0	-0.7	-0.8	-0.3	-1.1	0.2	-0.5	-1.0	0.2	1.4	0.1
Prospective memory result	0.1	0.1	0.3	-0.4	-0.2	-0.4	0.1	-0.3	0.2	0.2	0.3	0.4	0.5	-0.5
Pulse wave reflection index	0.1	0.1	0.3	0.1	0.4	0.5	-0.3	0.2	0.5	0.5	0.0	0.5	0.4	-0.2
Wheeze or whistling in the chest in last year	0.1	0.2	0.7	-0.8	-0.1	-0.8	-0.0	-0.4	0.3	-0.3	-0.1	0.3	0.2	0.2
Medication for pain relief, constipation, heartburn	0.1	0.2	1.3	-0.1	0.1	0.3	-0.1	0.3	-0.0	-0.3	-0.2	0.1	-1.1	-0.6
Pulse rate, automated reading	0.1	0.4	2.6	1.6	-0.4	-0.9	-0.1	-0.5	0.1	-0.1	-0.1	-0.1	0.2	0.9
Asthma (self-reported)	0.1	0.3	0.7	-0.7	0.1	-0.3	0.8	-0.1	0.5	-0.1	0.2	0.8	0.3	0.8
Ever smoked	0.1	0.2	1.4	0.1	0.2	0.3	-0.4	0.1	-0.2	-0.1	-0.4	-0.1	0.3	-1.2
Average weekly beer plus cider intake	0.1	0.2	1.1	0.0	-0.0	0.0	0.1	-0.4	-0.0	0.3	-1.0	0.6	0.6	0.0
Diastolic blood pressure, automated reading	0.1	0.4	1.1	0.5	0.5	0.8	0.3	0.7	0.7	0.4	-0.0	0.7	-0.5	1.1
Hair Pigment	0.0	1.2	2.6	1.4	1.3	0.7	1.1	1.1	1.6	1.0	0.2	1.4	-0.9	-0.2
Impedance of leg (right)	0.0	0.2	0.5	0.4	-0.4	-0.2	0.3	-0.5	0.1	-0.4	-0.4	0.4	0.7	-0.3

Hub : Genes

SPATA6L

Models

Trait associations