TWAS hub - SPATA9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1110	0.0390	1.5e-03	0.017	NA	0.065	NA	0.058	1.5e-02	NA	5.0e-06	NA	1.7e-05
2	GTEx	Adipose Visceral Omentum	0.1760	0.0670	2.2e-03	0.001	NA	0.000	NA	0.005	2.7e-01	NA	3.2e-01	NA	1.6e-01
3	GTEx	Colon Sigmoid	0.2130	0.0740	1.3e-03	0.116	NA	0.030	NA	0.055	6.9e-05	NA	3.1e-02	NA	5.2e-03
4	GTEx	Esophagus Gastroesophageal Junction	0.2110	0.0780	4.6e-03	0.039	NA	0.030	NA	0.038	1.5e-02	NA	3.0e-02	NA	1.7e-02
5	GTEx	Nerve Tibial	0.1174	0.0414	1.4e-03	0.037	NA	0.053	NA	0.055	1.2e-03	NA	1.2e-04	NA	8.8e-05
6	GTEx	Testis	0.4960	0.0590	1.8e-15	0.569	NA	0.546	NA	0.561	4.0e-30	NA	1.9e-28	NA	1.6e-29
7	METSIM	Adipose	0.0707	0.0265	8.4e-04	0.011	0.008	0.007	0.011	0.004	6.8e-03	2.2e-02	2.7e-02	0.0085	7.6e-02
8	TCGA	Bladder Urothelial Carcinoma	0.0430	0.0250	4.7e-03	0.052	0.023	0.042	NA	0.048	3.3e-05	4.3e-03	1.6e-04	NA	6.7e-05
9	TCGA	Breast Invasive Carcinoma	0.0222	0.0120	6.9e-04	0.015	0.011	0.009	NA	0.014	3.2e-04	1.6e-03	5.0e-03	NA	4.9e-04
10	TCGA	Colon Adenocarcinoma	0.0660	0.0360	7.3e-03	0.026	0.019	0.019	NA	0.037	1.1e-02	2.8e-02	2.6e-02	NA	3.4e-03
11	TCGA	Glioblastoma Multiforme	0.3810	0.1170	3.5e-03	0.107	0.023	0.062	NA	-0.007	3.8e-04	6.7e-02	5.9e-03	NA	5.8e-01
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.0381	0.0194	1.1e-03	0.038	0.026	0.022	NA	0.023	3.7e-05	6.0e-04	1.5e-03	NA	1.2e-03
13	TCGA	Brain Lower Grade Glioma	0.0989	0.0301	1.9e-12	0.126	0.120	0.122	NA	0.124	3.9e-14	1.7e-13	1.1e-13	NA	6.4e-14
14	TCGA	Lung Adenocarcinoma	0.0472	0.0193	9.8e-06	0.068	0.043	0.057	NA	0.064	2.2e-08	7.8e-06	2.9e-07	NA	6.3e-08
15	TCGA	Lung Squamous Cell Carcinoma	0.0335	0.0204	4.1e-03	0.010	0.017	0.010	NA	0.007	2.4e-02	4.0e-03	2.4e-02	NA	4.9e-02
16	TCGA	Pancreatic Adenocarcinoma	0.0700	0.0350	3.2e-03	0.016	0.060	0.013	NA	0.010	6.9e-02	1.7e-03	9.0e-02	NA	1.2e-01
17	TCGA	Prostate Adenocarcinoma	0.0925	0.0416	3.3e-06	0.075	0.060	0.063	NA	0.070	2.8e-08	7.2e-07	4.0e-07	NA	8.1e-08
18	TCGA	Soft Tissue Sarcoma	0.0670	0.0290	8.5e-05	0.079	0.082	0.073	NA	0.076	2.1e-05	1.4e-05	4.0e-05	NA	2.9e-05
19	TCGA	Thyroid Carcinoma	0.0920	0.0350	2.8e-09	0.114	0.087	0.098	NA	0.101	3.4e-11	8.2e-09	9.5e-10	NA	4.9e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Medication: Laxatives (e.g. Dulcolax, Senokot)	9.1	10.7	15.5	2.9	3.8	1.5	-1.5	3.0	3.8	2.4	3.6	3.4	3.6	-0.6	3.8	3.8	3.9	3.7	3.9	3.6	3.3	3.6
Leg pain on walking	7.6	9.5	13.2	-3.5	-3.5	-2.8	1.3	-3.2	-3.2	-3.2	-3.4	-3.6	-1.6	-2.6	-2.9	-3.3	-3.1	-3.4	-2.6	-3.4	-3.3	-3.3
Lung FEV1/FVC ratio	6.8	34.7	185.0	0.7	6.1	13.6	-0.7	1.9	4.5	1.4	4.2	5.0	6.8	-2.1	7.5	5.9	4.3	7.7	9.2	5.0	3.3	5.2
Eye problems/disorders: None of the above	3.1	3.5	7.6	2.1	2.1	0.3	0.4	2.4	2.2	1.7	2.4	2.5	1.0	0.7	1.7	1.9	2.1	1.1	1.0	2.4	2.7	2.2
Alcohol usually taken with meals	2.8	4.5	9.4	-2.0	-2.4	-0.2	-0.9	-1.4	-2.1	-2.6	-2.2	-2.0	-2.5	1.3	-2.2	-2.4	-2.2	-2.7	-3.1	-2.2	-2.1	-2.1
Loneliness, isolation	2.7	3.7	10.7	1.5	1.5	0.7	3.3	1.7	1.9	1.6	2.2	2.1	1.8	-0.8	2.1	2.0	1.8	1.8	2.0	2.3	1.8	2.1
Ever had bowel cancer screening	2.7	3.2	5.0	-0.8	-2.2	-1.6	-1.1	-1.6	-1.9	-1.3	-2.0	-1.9	-1.7	1.2	-1.9	-1.8	-1.8	-1.8	-2.2	-1.9	-2.2	-2.0
Taking other prescription medications	2.6	4.0	7.2	-2.3	-1.7	0.3	-0.0	-2.3	-2.4	-2.1	-2.7	-2.3	-1.9	0.2	-2.0	-2.2	-2.4	-1.3	-1.0	-2.5	-2.5	-2.5
Pain all over the body in last month	2.4	2.6	6.9	1.5	1.4	1.2	1.2	0.9	1.6	1.0	1.8	1.9	2.6	0.2	2.3	2.0	1.7	1.3	1.4	2.0	1.0	1.8
Eye problems/disorders: Cataract	2.4	2.8	6.9	-2.6	-1.5	-0.0	-0.2	-2.1	-2.0	-1.9	-1.9	-2.1	-0.8	-2.0	-1.3	-1.6	-1.9	-1.0	-0.8	-2.0	-1.9	-1.7
Ever had hysterectomy (womb removed)	2.3	2.6	6.4	1.0	1.5	2.5	-0.2	1.2	1.5	0.6	1.7	1.5	1.7	0.5	2.1	2.0	1.5	2.1	1.9	2.0	1.0	1.8
Mouth/teeth dental problems	2.3	3.5	7.0	-1.2	-2.0	-2.1	-0.5	-2.7	-1.8	-2.0	-2.0	-2.1	-0.3	-1.3	-1.7	-1.8	-1.7	-2.3	-1.7	-2.0	-2.6	-2.1
Prospective memory result	2.2	2.7	6.5	-0.2	-1.6	-2.5	-0.6	-2.2	-1.6	-1.9	-1.6	-1.9	0.0	-0.1	-1.4	-1.4	-1.5	-2.0	-1.8	-1.6	-2.5	-1.8
Shortness of breath walking on level ground	2.2	2.7	7.4	-1.0	-1.9	-2.7	0.0	-1.5	-1.3	-1.3	-1.3	-2.0	-0.8	-1.1	-1.5	-1.3	-1.2	-2.4	-2.2	-1.7	-2.0	-1.4
Illnesses of siblings: Diabetes	2.1	2.5	4.2	-1.1	-1.9	-1.6	0.1	-1.1	-1.6	-1.7	-1.8	-1.5	-2.0	0.4	-1.9	-2.0	-1.7	-1.9	-1.5	-1.7	-1.3	-1.8
Diabetes (mother)	2.0	2.6	6.9	-1.0	-1.4	-2.6	-1.8	-1.6	-1.5	-1.7	-1.6	-1.5	-1.0	-0.4	-1.9	-1.7	-1.5	-2.1	-1.5	-1.5	-1.4	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	6.8	-1.1	-1.7	-1.2	-0.7	-1.5	-1.5	-2.6	-1.4	-1.4	-0.9	0.6	-1.3	-1.5	-1.5	-1.8	-2.1	-1.5	-1.5	-1.4
Pack years adult smoking proportion	1.9	2.9	6.4	1.7	1.7	0.9	0.1	0.9	1.8	1.6	1.7	2.5	2.2	-1.1	1.7	1.8	1.7	1.6	2.3	1.8	1.7	1.7
Heart disease (mother)	1.9	2.3	8.3	2.9	1.7	0.5	-0.4	1.4	1.5	1.4	1.5	1.5	1.2	2.4	1.4	1.6	1.5	1.4	0.7	1.5	1.0	1.4
Hearing aid user	1.9	2.1	4.8	-2.0	-1.7	-0.0	1.8	-1.1	-1.5	-2.2	-1.5	-1.6	-1.3	0.7	-1.0	-1.3	-1.4	-0.9	-1.4	-1.7	-1.6	-1.4
Financial situation satisfaction	1.9	2.4	4.0	1.2	1.9	-0.8	0.8	1.9	1.8	0.8	1.9	1.5	1.5	-0.8	1.4	1.7	1.9	1.3	1.4	1.9	2.0	1.8
Medication for hormone replacement therapy	1.8	2.0	4.7	1.5	1.7	0.7	-0.2	2.1	1.6	1.2	1.8	1.9	0.3	0.5	1.1	1.4	1.5	1.1	0.7	1.4	2.2	1.7
Diabetes (father)	1.8	2.2	4.1	0.9	1.4	-0.3	0.2	1.7	1.5	0.9	1.7	1.1	1.3	-1.8	1.4	1.7	1.7	1.9	2.0	2.0	1.7	1.6
Lung cancer (father)	1.8	2.1	3.2	-1.0	-1.6	-1.2	0.3	-1.7	-1.8	-1.2	-1.6	-1.8	-1.5	-0.6	-1.7	-1.6	-1.8	-1.1	-1.0	-1.6	-1.6	-1.7
Medication: Omeprazole	1.8	2.1	3.9	-1.8	-2.0	-0.8	0.1	-1.2	-1.6	-1.1	-1.5	-1.8	-1.4	-0.4	-1.4	-1.4	-1.6	-1.6	-1.8	-1.6	-1.8	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	4.3	-1.2	-1.7	-0.7	1.1	-1.9	-1.4	-1.1	-1.7	-1.4	-0.7	-0.8	-1.2	-1.6	-1.4	-1.8	-1.5	-1.8	-2.1	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	4.3	-1.6	-2.1	-0.8	0.4	-1.3	-1.6	-1.3	-1.5	-1.8	-1.5	-0.1	-1.3	-1.4	-1.6	-1.6	-2.0	-1.6	-1.9	-1.4
Age at First Birth	1.7	2.4	8.2	0.9	1.8	2.9	-0.7	1.5	1.4	0.9	1.6	1.0	0.4	-0.1	1.5	1.8	1.5	2.3	1.8	1.7	1.3	2.0
Age when periods started (menarche)	1.7	4.1	7.6	-2.4	-2.3	-1.2	2.4	-2.2	-2.0	-1.6	-1.9	-2.5	-1.1	-0.6	-1.6	-1.6	-1.8	-2.1	-2.3	-2.5	-2.8	-1.9
Birth weight of first child	1.7	3.1	6.2	2.3	1.6	0.4	0.6	1.8	2.0	1.5	2.2	2.1	1.7	0.0	1.9	2.0	2.0	1.4	1.4	2.5	1.7	2.1
Mouth/teeth dental problems: Loose teeth	1.7	2.0	3.9	1.6	1.0	1.4	0.7	1.6	1.5	1.3	1.6	1.4	1.2	2.0	1.6	1.6	1.6	1.0	0.4	1.5	1.2	1.6
High cholesterol (Self-reported)	1.7	2.9	8.1	1.0	1.7	1.9	-0.2	0.7	1.6	0.4	1.8	1.6	2.8	-1.6	2.1	2.1	1.6	1.7	2.1	2.1	1.4	1.9
Mean Putamen Volume	1.6	1.9	3.0	0.0	1.7	1.0	-1.4	1.5	1.7	0.6	1.6	1.2	1.4	-0.3	1.6	1.7	1.7	1.2	1.3	1.6	1.3	1.6
Medication: Lisinopril	1.6	2.0	8.2	-1.3	-1.7	0.1	-0.1	-0.5	-1.6	-0.8	-1.4	-1.5	-2.9	0.4	-1.9	-1.7	-1.6	-1.0	-1.5	-1.7	-1.0	-1.4
Angina	1.5	2.0	4.1	2.0	1.4	1.1	1.0	0.9	1.5	0.5	1.7	1.6	1.7	-0.4	1.6	1.8	1.5	1.4	1.6	1.6	1.1	1.6
Pulse wave reflection index	1.5	1.9	3.6	-0.6	-1.4	-1.7	-0.6	-1.0	-1.4	-1.2	-1.3	-1.5	-1.4	1.4	-1.6	-1.4	-1.4	-1.5	-1.9	-1.3	-1.2	-1.3
Exposure to tobacco smoke outside home	1.5	2.0	6.0	1.8	1.1	-0.5	1.8	0.5	1.5	1.5	1.3	1.7	2.4	-1.5	1.2	1.1	1.4	0.9	1.5	1.3	1.4	1.1
Medication: Allopurinol	1.5	2.0	3.2	-0.9	-1.2	-0.4	1.2	-1.7	-1.6	-1.5	-1.8	-1.5	-1.2	0.0	-1.4	-1.7	-1.6	-1.5	-1.2	-1.7	-1.5	-1.7
Commuting to job workplace: Walk	1.5	1.6	2.5	1.4	0.6	1.1	0.4	1.2	1.6	1.4	1.4	1.5	1.1	0.7	1.5	1.4	1.6	1.2	1.0	1.5	1.4	1.4
Alzheimer’s Disease (in mother)	1.4	1.7	4.1	2.0	1.1	0.1	1.2	0.9	1.4	1.6	1.4	1.8	1.4	1.1	1.2	1.2	1.3	0.7	0.4	1.3	1.4	1.3
Coronary Artery Disease (CAD)	1.4	1.7	4.3	-1.3	-1.3	-2.1	-0.5	-1.4	-1.6	-0.0	-1.5	-1.8	-0.9	-0.5	-1.2	-1.3	-1.4	-1.0	-0.8	-1.2	-1.7	-1.5
Primary Biliary Cirrhosis	1.4	2.0	6.0	1.6	2.4	0.6	0.3	0.7	1.4	1.4	1.3	1.4	1.6	0.3	1.6	1.6	1.5	1.8	1.8	1.7	0.7	1.2
Supplements: Zinc	1.4	1.6	3.4	-0.3	-1.7	-0.3	1.8	-1.0	-1.3	-0.2	-1.2	-1.0	-1.4	1.3	-1.4	-1.3	-1.4	-1.3	-1.6	-1.5	-1.0	-1.2
Current tobacco smoking	1.4	2.3	5.0	1.6	1.2	0.9	1.3	0.8	1.4	1.9	1.6	1.6	1.6	-0.4	1.3	1.6	1.3	1.9	2.2	1.8	1.8	1.5
Stomach or abdominal pain in last month	1.4	1.7	2.5	0.4	1.5	-0.3	-0.9	1.4	1.4	1.5	1.6	1.1	1.4	-1.5	1.2	1.5	1.5	1.2	1.3	1.4	1.5	1.5
Medication: Cholesterol lowering	1.4	2.2	3.8	1.2	2.0	1.8	-1.0	0.7	1.5	0.1	1.6	1.6	1.9	-0.0	1.8	1.8	1.4	1.4	1.9	1.9	1.0	1.6
Alcohol drinker status: Previous	1.4	1.6	3.2	0.4	-0.8	-1.1	-0.3	-1.6	-1.4	-0.2	-1.6	-1.1	-1.4	0.6	-1.8	-1.5	-1.4	-1.1	-1.0	-1.5	-1.5	-1.7
Heart attack	1.3	1.6	7.4	-2.7	-1.2	-0.2	0.7	-1.1	-1.3	-1.4	-1.4	-1.5	-0.9	-0.7	-1.0	-1.3	-1.3	-1.2	-0.9	-1.0	-1.3	-1.3
Angina (self-reported)	1.3	1.8	3.6	1.9	1.2	1.2	1.1	0.9	1.4	0.4	1.6	1.5	1.6	-0.2	1.4	1.7	1.4	1.2	1.4	1.5	1.1	1.6
Supplements: Vitamin C	1.3	1.5	4.2	0.7	-1.1	-2.1	1.4	-0.3	-1.0	0.3	-1.0	-0.6	-1.6	1.2	-1.6	-1.4	-1.0	-1.3	-1.6	-1.7	-0.3	-1.3
Fractured/broken bones in last 5 years	1.3	1.7	4.4	1.9	1.4	0.9	-0.7	1.5	1.2	1.5	1.3	1.6	0.5	2.1	0.8	1.1	1.1	1.2	0.8	1.0	1.7	1.3
Pack years of smoking	1.3	1.9	4.6	1.4	1.3	0.8	-0.0	0.6	1.5	1.2	1.3	2.1	2.0	-0.9	1.4	1.4	1.4	1.2	1.9	1.4	1.4	1.3
Alzheimer’s Disease (including proxy)	1.2	1.7	2.9	1.6	1.3	1.2	0.7	0.8	1.4	1.0	1.6	1.7	1.3	0.7	1.4	1.6	1.3	1.3	0.9	1.6	1.1	1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	3.7	1.3	0.9	-1.4	1.9	1.2	1.1	1.4	1.3	0.9	0.8	-0.6	0.9	1.3	1.2	1.5	1.5	1.6	1.1	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.2	2.7	4.6	-1.7	-1.8	-0.4	0.1	-1.9	-1.9	-2.1	-2.0	-1.7	-1.3	0.1	-1.6	-1.9	-2.0	-1.5	-1.2	-2.1	-1.7	-1.9
Medication: Atenolol	1.2	1.5	8.0	0.4	1.1	2.8	-1.0	0.7	0.9	-0.1	1.1	0.7	0.8	0.1	1.5	1.4	0.9	1.8	1.9	0.9	0.8	1.3
Number of live births	1.2	1.7	3.8	-0.7	-1.3	-1.6	0.9	-1.0	-1.5	-0.9	-1.4	-1.9	-0.8	1.7	-1.0	-1.1	-1.3	-0.6	-0.9	-1.4	-1.7	-1.5
Age at first live birth	1.2	2.1	5.8	0.8	1.4	2.4	-0.6	1.6	1.2	1.3	1.5	1.3	0.8	0.5	1.6	1.6	1.2	2.1	1.6	1.5	1.4	1.6
Health satisfaction	1.2	1.6	6.2	-2.2	-0.7	-2.4	1.7	-0.2	-0.8	-0.7	-0.7	-1.8	-0.9	-2.5	-0.9	-0.6	-0.6	-0.1	-0.3	-0.6	-0.8	-0.7
Commuting to job workplace: Car/motor vehicle	1.2	1.3	5.1	-2.2	-0.6	-0.9	-1.2	-0.3	-1.1	-1.3	-0.8	-1.1	-1.6	-2.2	-1.1	-0.8	-1.0	-0.5	-0.6	-0.9	-0.6	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.2	3.6	-1.1	-0.8	-1.6	0.7	-0.4	-1.0	-0.7	-1.1	-1.3	-1.1	0.2	-0.9	-1.0	-0.8	-1.5	-1.9	-1.3	-1.3	-1.1
Smoking status: Current	1.2	1.8	4.4	1.4	0.9	0.9	1.5	0.3	1.1	1.9	1.3	1.3	1.7	-0.5	1.1	1.4	1.0	1.7	2.1	1.6	1.5	1.3
Wears glasses or contact lenses	1.2	1.4	5.7	-0.7	-0.7	1.0	-2.1	-1.4	-1.0	-2.4	-1.1	-1.1	-0.4	0.2	-0.6	-0.8	-1.0	-1.1	-0.9	-1.4	-1.5	-1.0
Eye problems/disorders: Glaucoma	1.2	1.4	3.6	-0.8	-1.6	1.0	-0.2	-1.9	-1.3	-0.4	-1.6	-1.0	-0.2	-0.5	-0.9	-1.4	-1.4	-0.9	-0.4	-1.4	-1.7	-1.4
Ovarian Cancer	1.1	1.5	4.5	-0.4	-1.6	-2.1	-0.4	-0.8	-0.8	-1.5	-0.9	-0.7	-0.8	-1.1	-1.2	-1.3	-0.9	-2.0	-1.8	-0.9	-1.1	-1.0
Relative age of first facial hair	1.1	2.2	8.3	-2.9	-1.6	2.3	-1.5	-1.9	-1.6	-1.2	-1.7	-1.1	-0.6	-1.3	-0.6	-1.3	-1.7	-0.2	0.0	-1.4	-1.4	-1.3
Ever used hormone-replacement therapy (HRT)	1.1	1.4	3.1	-0.2	-1.8	-1.7	-0.5	-1.4	-1.1	-0.9	-1.1	-1.1	-0.2	1.2	-1.1	-1.0	-1.1	-1.4	-1.6	-1.2	-1.4	-1.2
Medication: Metformin	1.1	1.5	4.7	2.2	1.4	0.5	0.9	1.6	1.2	1.9	1.2	1.2	0.1	1.5	0.5	1.0	1.1	1.1	0.7	1.2	1.6	1.1
Illnesses of siblings	1.1	1.5	4.3	0.7	1.2	1.8	-2.1	1.1	1.1	1.4	1.2	1.2	0.8	0.8	1.4	1.1	1.1	1.0	0.6	1.3	1.0	1.3
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	5.2	-1.0	-2.0	-2.3	0.9	-0.7	-1.3	-0.2	-1.3	-1.4	-1.5	-0.9	-1.6	-1.5	-1.2	-1.2	-1.5	-1.5	-0.7	-1.4
Age at last live birth	1.1	1.6	4.2	0.5	1.3	1.8	-1.4	1.4	0.9	1.4	1.1	0.8	0.7	0.2	1.1	1.2	0.9	2.1	1.8	1.3	1.3	1.2
Average weekly beer plus cider intake	1.1	1.5	3.9	0.2	1.4	0.7	-0.9	1.2	1.1	1.4	1.2	1.0	0.7	-0.6	1.4	1.4	1.2	2.0	1.9	1.4	1.4	1.2
Time employed in main current job	1.0	1.1	2.9	-1.2	-1.2	-1.4	1.1	-0.0	-0.7	-1.7	-0.7	-0.9	-1.0	-1.1	-1.0	-0.8	-0.6	-1.5	-1.3	-1.0	-0.6	-0.7
Chronic bronchitis/emphysema (mother)	1.0	1.2	6.4	0.9	1.3	-0.2	2.5	-0.0	0.5	1.6	1.0	1.0	1.2	-0.9	0.8	0.9	0.4	0.8	1.3	1.2	0.6	0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	6.1	0.0	1.9	1.2	-0.2	0.8	1.2	0.5	1.3	0.8	2.5	-1.9	1.8	1.7	1.4	1.8	2.1	1.5	0.8	1.4
Qualifications: nursing, teaching	1.0	1.5	4.2	-1.1	-2.0	0.2	-1.1	-0.8	-1.5	-2.0	-1.1	-1.3	-1.6	0.4	-1.4	-1.2	-1.6	-0.8	-1.1	-1.1	-0.7	-1.0
Leg fat percentage (left)	1.0	3.8	6.9	1.2	2.4	1.2	-0.2	2.3	2.0	2.1	2.2	2.0	1.4	-0.5	1.8	2.1	2.0	2.2	2.3	2.2	2.6	2.1
Schizophrenia vs Biploar Disorder	0.9	1.1	2.8	1.7	1.0	-0.1	1.1	1.0	1.1	1.5	1.2	1.2	1.1	0.8	1.0	1.2	1.1	0.8	0.5	1.2	0.9	1.1
Verbal and Numeric Reasoning (VNR)	0.9	2.1	7.3	0.5	2.0	1.1	-2.3	2.7	1.3	-0.2	1.6	1.0	-0.4	0.6	1.2	1.4	1.4	1.5	0.5	1.5	1.9	1.7
Type 2 Diabetes (T2D) (2018)	0.9	1.6	4.3	2.1	1.3	-1.3	0.1	1.5	1.2	1.8	1.4	1.4	1.0	0.8	0.7	1.1	1.2	0.7	0.8	1.4	1.6	1.1
Diabetes (self-reported)	0.9	1.4	2.8	1.0	1.7	0.3	1.0	1.5	1.3	0.8	1.3	1.2	0.9	0.2	1.0	1.2	1.3	1.2	1.5	1.4	1.5	1.2
Fluid intelligence score	0.9	2.0	6.4	0.0	1.8	0.5	-1.8	2.5	1.2	1.0	1.7	1.2	-0.5	-0.5	1.0	1.4	1.3	1.4	0.7	1.5	2.2	1.7
Arm fat percentage (right)	0.9	3.5	5.9	0.7	2.4	0.5	0.2	2.1	2.1	1.0	2.2	2.0	1.6	-1.7	1.8	2.0	2.1	1.8	2.1	2.2	2.4	2.1
Body fat percentage	0.9	3.5	5.9	0.2	2.4	1.2	-0.5	2.0	2.0	0.9	2.1	1.9	1.6	-1.8	1.8	2.1	2.0	2.0	2.4	2.2	2.4	2.1
Leg fat percentage (right)	0.9	3.4	5.9	0.8	2.4	1.2	-0.2	2.0	1.9	1.8	2.0	1.9	1.5	-1.0	1.8	2.0	1.9	2.1	2.3	2.1	2.4	2.0
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.0	6.2	0.8	1.4	0.6	0.3	1.2	0.8	2.5	0.7	1.1	-0.4	0.4	0.2	0.5	0.8	1.4	1.0	0.7	1.4	0.6
Alcohol drinker status: Never	0.9	1.0	5.2	-1.8	-0.6	1.1	-1.1	-1.1	-0.6	-1.8	-0.7	-0.7	0.5	-2.3	-0.2	-0.5	-0.6	-0.6	-0.0	-0.6	-0.7	-0.5
HDL Cholesterol	0.8	1.4	2.8	-1.5	-1.0	0.0	-1.6	-0.8	-1.2	-1.7	-1.3	-1.2	-1.7	-0.8	-1.3	-1.4	-1.3	-0.7	-0.6	-1.3	-0.7	-1.1
Lung FVC	0.8	4.2	15.8	-0.0	-1.5	-4.0	1.7	-0.8	-1.7	0.5	-2.0	-1.9	-2.7	2.0	-2.7	-2.4	-1.7	-1.8	-2.7	-1.9	-1.2	-2.2
Townsend deprivation index at recruitment	0.8	1.1	3.6	0.7	1.6	0.0	0.0	1.2	1.1	1.4	1.1	1.4	0.4	-1.5	0.4	0.6	0.9	0.5	0.9	1.1	1.9	1.0
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.3	-1.5	-1.0	-0.3	-1.4	-1.3	-1.2	0.2	-1.1	-0.8	-0.5	-1.1	-0.8	-1.1	-1.3	-0.8	-0.7	-0.7	-0.6	-1.0
High blood pressure (mother)	0.8	1.1	2.3	-1.5	-0.7	0.7	-0.2	-0.7	-1.1	-1.1	-1.1	-1.0	-1.1	-1.4	-1.3	-1.3	-1.2	-0.7	-0.8	-1.2	-0.5	-1.0
Hip circumference	0.8	3.4	5.7	1.0	2.3	0.0	0.3	1.9	2.2	1.4	2.2	1.9	2.4	-1.1	2.0	2.2	2.2	1.5	1.9	2.2	1.9	2.1
Glaucoma (self-reported)	0.8	0.9	3.5	-0.9	-1.2	1.9	-1.0	-1.4	-0.9	0.3	-1.2	-0.4	-0.2	-0.5	-0.7	-1.1	-1.1	-0.3	0.2	-1.1	-0.7	-1.0
Gout (self-reported)	0.8	1.0	2.5	-0.5	-0.8	-0.4	1.2	-1.5	-1.1	-1.6	-1.2	-0.8	-0.3	-0.4	-0.6	-1.0	-1.1	-1.1	-0.8	-1.1	-1.3	-1.1
Medication: Amlodipine	0.8	1.2	3.0	-1.1	-0.6	0.8	-1.7	-1.5	-1.3	-1.3	-1.2	-1.0	-0.2	-0.7	-0.8	-0.9	-1.3	-0.7	-0.3	-1.1	-1.5	-1.1
Number of full brothers	0.8	1.0	4.8	1.1	0.1	1.8	0.6	-0.7	0.7	0.9	0.7	1.3	2.2	-0.5	1.2	0.7	0.6	0.3	1.1	0.6	0.6	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	2.2	0.6	0.6	0.5	-0.1	1.2	1.1	0.9	1.2	1.1	0.7	-0.8	1.0	1.1	1.1	1.4	1.5	1.5	1.2	1.2
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	4.6	-1.7	-0.5	0.8	-1.0	-0.9	-0.8	-2.1	-1.1	-0.9	-0.8	0.3	-0.6	-1.0	-0.9	-0.8	-0.4	-1.1	-0.9	-0.9
Arm fat percentage (left)	0.8	3.3	5.7	0.4	2.4	0.5	0.3	2.1	2.1	0.6	2.1	1.9	1.7	-1.9	1.9	2.0	2.1	1.8	2.1	2.2	2.3	2.1
Number of operations (self-reported)	0.8	1.1	3.8	-0.7	-1.9	-0.3	-0.5	-1.1	-1.2	-1.1	-1.2	-1.2	-0.3	-0.2	-1.1	-1.2	-1.2	-1.0	-1.1	-1.1	-1.1	-1.2
Heart attack/myocardial infarction (self-reported)	0.8	1.1	5.5	-2.3	-1.1	0.1	0.7	-0.9	-1.1	-0.9	-1.1	-1.2	-0.7	-0.4	-0.8	-1.1	-1.1	-1.0	-0.7	-0.7	-1.0	-1.0
Heart disease (siblings)	0.8	1.0	2.5	-0.9	-1.6	-0.2	1.1	-1.5	-1.0	-0.6	-1.1	-0.9	0.2	-1.1	-0.8	-1.0	-1.0	-1.2	-0.6	-1.1	-1.0	-1.1
Chronotype (morning person)	0.7	1.6	3.8	-0.3	-0.8	-1.3	1.1	-1.5	-1.2	-1.0	-1.1	-1.6	-0.5	0.3	-1.2	-0.9	-1.1	-1.9	-1.9	-1.5	-1.7	-1.2
Trunk fat percentage	0.7	2.9	4.8	-0.1	2.1	1.1	-0.5	1.6	1.8	0.6	1.9	1.6	1.7	-1.8	1.7	1.9	1.8	1.7	2.2	2.1	2.1	1.9
Qualifications: CSEs or equivalent	0.7	1.0	2.3	0.2	1.1	0.1	1.2	1.2	1.1	1.0	1.1	1.2	0.5	-1.0	0.7	0.8	1.1	0.8	1.1	0.7	1.5	1.0
Body mass index (BMI)	0.7	3.0	5.2	1.6	2.3	0.0	0.6	1.9	2.0	1.8	1.9	1.8	1.7	-0.6	1.6	1.8	2.0	1.6	1.8	2.0	2.1	1.8
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	8.0	0.6	0.1	0.7	2.8	1.1	0.5	1.4	0.7	0.5	-0.3	-0.5	0.4	0.7	0.5	1.4	1.0	0.9	0.7	0.7
Had other major operations	0.7	0.8	2.4	-1.4	-1.4	-0.7	0.3	-0.2	-1.0	-0.8	-0.7	-1.2	-1.6	-0.5	-1.0	-0.8	-0.9	-0.5	-0.9	-0.6	-0.6	-0.7
Financial difficulties in last 2 years	0.7	0.9	3.4	0.9	0.5	0.2	0.5	0.0	0.8	1.5	0.9	0.9	1.8	-1.8	0.7	1.0	0.7	0.5	1.0	0.7	0.5	0.9
Mouth/teeth dental problems: Dentures	0.7	1.2	3.2	0.7	1.4	0.5	1.8	1.0	1.1	1.0	1.0	1.4	0.8	-0.4	0.8	0.9	1.0	1.1	1.2	1.3	1.4	1.0
Loud music exposure frequency	0.7	0.8	4.6	-1.3	-1.2	-0.8	2.1	-0.2	-0.6	-0.3	-0.5	-0.7	-0.9	-1.3	-0.5	-0.5	-0.5	-0.4	-0.4	-0.8	-0.7	-0.5
Leg fat mass (right)	0.7	2.5	4.6	0.9	2.1	0.4	-0.4	1.4	1.7	1.6	1.8	1.6	1.8	-1.2	1.5	1.8	1.7	1.6	1.9	1.9	1.9	1.7
Diabetes diagnosed by doctor	0.7	1.2	2.3	1.5	1.1	-0.0	1.4	1.3	1.2	1.0	1.1	1.4	0.9	0.5	0.8	0.8	1.1	0.8	1.0	1.1	1.4	0.9
Friendships satisfaction	0.7	0.8	6.7	0.7	0.9	0.4	2.6	0.8	0.5	0.9	0.7	0.5	-0.4	-0.8	0.1	0.5	0.5	0.8	1.1	0.8	0.9	0.7
Irritability	0.7	1.1	3.7	0.2	0.9	1.1	1.5	0.6	0.6	0.0	1.0	0.2	0.8	-0.8	1.5	1.5	0.7	1.9	1.7	1.3	0.2	1.1
Leg fat mass (left)	0.7	2.7	4.5	1.0	2.1	0.4	-0.3	1.6	1.8	1.8	1.9	1.7	1.8	-1.1	1.5	1.8	1.8	1.6	1.9	2.0	2.0	1.8
HbA1C	0.6	0.7	5.5	1.1	-0.3	-0.1	1.8	0.5	-0.0	0.6	-0.2	-0.2	-1.0	2.4	-0.3	-0.3	0.0	-0.3	-0.6	-0.2	-0.2	-0.2
Number of treatments/medications taken	0.6	1.1	3.6	-1.9	-0.6	0.3	-0.9	-1.2	-1.1	-1.7	-1.1	-0.9	-0.5	-1.7	-0.5	-0.8	-1.1	-0.6	0.1	-0.9	-1.3	-1.0
Medication: Co-codamol	0.6	0.7	2.7	1.6	0.9	0.8	0.1	0.6	0.8	0.7	0.8	1.1	0.5	0.0	0.4	0.7	0.8	0.8	1.0	0.9	0.9	0.8
Hayfever, allergic rhinitis or eczema	0.6	1.4	3.3	-0.1	1.8	1.1	-0.1	1.4	1.1	1.2	1.2	1.1	0.4	-0.4	1.1	1.2	1.1	1.5	1.4	1.4	1.5	1.3
Trunk fat mass	0.6	2.5	4.8	0.3	2.2	0.6	-0.5	1.4	1.6	1.0	1.7	1.5	1.9	-1.6	1.5	1.8	1.6	1.6	2.0	1.9	1.8	1.7
Forced vital capacity (FVC)	0.6	2.4	10.5	-0.6	-1.1	-3.2	1.1	-1.3	-1.6	0.2	-1.7	-1.8	-1.2	0.7	-1.7	-1.6	-1.4	-1.3	-1.6	-1.5	-1.9	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	3.2	-1.2	-1.1	-0.2	-1.2	-1.4	-1.4	-1.8	-1.4	-1.1	-1.0	-0.6	-1.1	-1.3	-1.5	-0.8	-0.4	-1.4	-0.9	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.4	-1.6	-0.6	0.3	-0.8	-1.3	-1.0	-0.5	-1.0	-0.9	-0.1	-1.3	-0.5	-0.7	-1.0	-0.3	0.0	-0.9	-0.8	-0.9
Arm fat mass (right)	0.6	2.7	4.8	0.9	2.2	-0.1	0.2	1.6	1.8	1.4	1.9	1.6	2.0	-1.4	1.5	1.9	1.8	1.5	1.9	2.0	1.8	1.8
Medication: Seretide 50 evohaler	0.6	0.7	2.2	-0.0	1.2	0.2	1.3	1.2	0.6	0.8	0.6	0.2	-0.2	1.5	0.5	0.8	0.7	1.3	0.5	0.5	0.6	0.6
Whole body fat mass	0.6	2.7	4.8	0.6	2.2	0.5	-0.4	1.5	1.7	1.2	1.9	1.7	1.9	-1.6	1.6	1.8	1.7	1.6	2.1	2.0	2.0	1.8
Number of full sisters	0.6	0.8	3.3	-0.3	1.3	1.4	1.0	0.9	0.6	0.6	0.4	0.2	-0.1	0.5	0.8	0.8	0.8	1.8	1.4	0.7	0.2	0.5
Mood swings	0.6	1.2	8.3	1.0	0.3	-0.2	2.9	0.8	0.9	0.8	1.0	0.7	1.2	-0.3	1.0	1.0	0.9	1.0	1.0	1.1	0.7	0.9
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.4	-0.2	0.7	1.1	-0.5	1.8	0.6	1.2	0.9	0.4	-0.7	0.7	0.7	0.8	0.7	1.6	0.7	0.8	1.3	1.0
Arm fat mass (left)	0.6	2.6	4.9	0.6	2.2	-0.0	0.2	1.5	1.8	1.1	1.9	1.6	2.1	-1.7	1.6	1.8	1.8	1.4	1.8	1.9	1.8	1.7
Medication: Blood pressure	0.6	1.2	5.0	-1.9	-1.1	0.0	-0.3	-0.4	-1.1	-0.0	-1.2	-1.1	-2.2	-0.0	-1.4	-1.3	-1.1	-0.6	-0.8	-1.2	-0.6	-1.2
Risk taking	0.6	0.9	2.5	1.1	0.7	1.5	1.0	0.4	0.4	1.6	0.4	1.1	0.8	1.4	0.6	0.5	0.3	1.2	1.1	0.6	1.0	0.4
Depressed Affect (Nagel 2018)	0.5	1.1	6.0	0.8	0.5	0.1	2.4	0.7	0.5	1.4	1.0	0.5	0.9	0.3	1.2	1.3	0.6	1.6	1.3	1.1	0.6	1.0
Bipolar Disorder (2011)	0.5	0.5	3.2	-1.7	-0.9	0.2	-1.8	0.0	-0.4	-1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Fasting Glucose	0.5	0.6	5.0	1.1	-0.6	-1.5	0.7	0.8	-0.1	0.1	-0.1	-0.2	-1.1	2.2	-0.5	-0.3	0.0	-0.4	-0.8	-0.3	0.0	-0.2
Smoking Status	0.5	1.2	2.6	1.6	1.1	-0.0	1.6	0.4	1.0	0.9	1.2	0.9	1.4	0.8	1.2	1.4	1.0	1.2	1.2	1.3	0.9	1.1
Average weekly spirits intake	0.5	0.6	3.1	1.8	0.9	-1.2	1.7	0.3	0.6	1.2	0.4	0.6	0.4	0.5	-0.0	0.3	0.6	-0.1	0.1	0.2	0.4	0.2
Vitamin and mineral supplements	0.5	0.6	1.8	-0.7	-1.0	-0.4	0.9	-1.0	-1.0	0.5	-0.7	-1.3	-0.6	0.3	-0.8	-0.6	-0.9	-0.6	-0.7	-0.6	-1.1	-0.7
Serious illness, injury or assault to yourself	0.5	0.6	1.2	1.0	0.9	-0.3	-0.6	0.9	0.7	1.0	0.9	0.7	0.5	0.1	0.6	0.8	0.7	0.8	0.6	1.1	0.9	0.8
Supplements: Glucosamine	0.5	0.6	2.7	-1.2	-0.2	-0.3	-0.8	-0.6	-0.9	-1.6	-0.8	-0.9	-0.8	-0.1	-0.5	-0.5	-0.9	0.2	-0.2	-0.9	-0.9	-0.7
Waist circumference	0.5	2.0	3.9	0.8	1.5	0.3	-1.2	1.1	1.5	1.1	1.5	1.5	2.0	-1.7	1.5	1.6	1.5	1.3	1.7	1.5	1.5	1.5
Had menopause	0.5	0.6	4.4	0.8	-0.8	-0.6	0.6	-0.9	-0.5	0.1	-0.4	-0.2	-0.3	2.1	-0.6	-0.4	-0.5	-0.9	-1.1	-0.5	-0.6	-0.5
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.1	0.5	1.2	0.9	0.6	0.8	0.7	0.3	0.8	0.6	0.2	-0.2	0.8	0.9	0.7	1.4	1.1	0.8	0.9	0.8
Worrier / anxious feelings	0.5	0.9	3.3	-0.5	-1.8	-0.3	0.2	-1.1	-1.2	-0.3	-0.9	-1.5	-0.9	-0.0	-0.9	-0.8	-1.0	-0.6	-1.0	-0.9	-1.5	-0.9
Noisy workplace	0.5	0.6	3.6	0.7	0.4	0.1	1.8	-0.1	0.6	1.9	0.4	0.6	0.7	-0.2	0.6	0.5	0.6	0.5	0.7	0.5	0.0	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.4	0.6	-0.1	0.7	-0.9	0.9	1.1	0.2	1.1	0.9	1.0	-0.1	1.2	0.9	1.1	0.4	0.5	1.2	0.6	1.1
Headache pain in last month	0.5	0.9	4.3	-1.9	-0.3	1.2	-0.5	-0.2	-0.9	-0.7	-0.8	-1.0	-1.1	-2.1	-0.5	-0.5	-0.8	0.0	-0.1	-1.1	-0.6	-0.6
Forced vital capacity (FVC), Best measure	0.5	1.9	5.9	-0.6	-1.0	-2.4	0.3	-1.4	-1.5	-0.3	-1.6	-2.0	-0.9	0.7	-1.5	-1.4	-1.3	-0.8	-1.2	-1.3	-1.9	-1.7
Neck or shoulder pain in last month	0.5	0.6	6.7	-1.3	0.5	-1.4	-0.1	0.3	0.3	-0.2	0.3	0.2	0.5	-2.6	0.6	0.2	0.3	-0.5	0.0	0.4	0.2	0.3
Suffer from ‘nerves’	0.5	0.8	3.4	0.1	0.5	0.4	1.8	0.9	0.9	0.3	0.9	0.7	0.6	-1.1	0.9	0.8	1.0	1.0	1.1	0.9	0.9	1.0
Average weekly red wine intake	0.5	0.8	2.8	-0.7	-0.7	0.9	-1.5	-0.8	-0.9	-1.7	-0.8	-0.8	-0.7	0.5	-0.8	-0.7	-0.9	-0.6	-0.8	-0.7	-0.7	-0.6
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.1	-0.3	0.9	1.4	-1.1	1.2	0.8	0.1	0.6	1.0	-0.3	0.7	0.8	0.4	0.8	0.8	0.5	0.5	1.1	0.7
Myopia	0.5	0.7	2.8	1.7	0.8	-0.6	-0.6	1.0	0.8	0.2	1.0	0.8	-0.2	1.1	0.2	0.6	0.7	-0.1	-0.4	0.8	1.2	0.9
Bipolar Disorder (2018)	0.4	0.7	2.8	-1.0	-0.0	1.6	-1.7	-1.1	-0.7	-0.8	-1.0	-0.1	-0.0	0.4	-0.1	-0.7	-0.8	0.3	0.9	-0.1	-0.9	-0.9
Neuroticism (Nagel 2018)	0.4	0.9	5.6	0.4	0.5	1.0	2.4	0.5	0.3	1.1	0.7	0.2	0.0	0.1	0.9	0.9	0.3	1.6	1.3	0.8	0.4	0.7
Prostate Cancer	0.4	0.6	1.9	0.8	0.6	-0.2	-1.4	1.1	0.8	1.0	0.8	1.0	0.2	0.1	0.6	0.5	0.7	0.1	0.0	0.5	1.2	0.8
Hypothyroidism (self reported)	0.4	0.8	1.5	-0.8	-0.6	0.4	-0.5	-1.2	-1.2	-1.2	-1.1	-0.8	-0.6	0.8	-0.6	-1.0	-1.2	-0.7	-0.5	-1.1	-1.1	-1.1
Average weekly fortified wine intake	0.4	0.5	3.0	-1.7	-0.1	0.9	0.3	0.3	-0.5	-0.8	-0.1	-0.6	-0.9	-1.5	-0.2	-0.1	-0.5	0.1	-0.0	-0.1	0.1	0.1
Maternal smoking around birth	0.4	0.6	2.7	1.5	0.5	0.0	0.9	0.4	0.4	1.5	0.5	0.3	0.7	1.6	0.4	0.6	0.5	0.5	0.2	0.5	0.2	0.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	0.9	0.2	0.7	-0.2	0.3	0.8	0.9	0.9	0.6	1.0	0.6	-0.1	0.8	0.5	0.9	0.7	0.5	0.5	0.9	0.5
Chronic bronchitis/emphysema (father)	0.4	0.4	3.0	0.2	-0.2	-1.7	0.9	-0.1	-0.3	-0.6	-0.4	-0.0	-0.2	-0.3	-0.7	-0.7	-0.3	-0.8	-0.9	-0.8	0.2	-0.5
Qualifications: None of the above	0.4	0.9	3.0	0.4	-1.1	-1.7	0.8	-1.1	-0.8	0.9	-0.8	-1.0	-0.4	0.4	-1.2	-0.8	-0.7	-1.2	-1.1	-0.8	-1.1	-1.0
Medication: Simvastatin	0.4	0.5	3.9	-0.2	0.8	0.9	-2.0	-0.0	0.3	-0.1	0.3	0.4	1.0	-1.0	0.6	0.5	0.3	0.5	0.7	0.7	0.2	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	4.0	0.6	0.0	-0.8	2.0	-0.0	-0.1	1.4	0.4	-0.1	0.5	-1.2	0.2	0.6	0.0	1.1	0.9	0.6	0.2	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	2.9	0.3	-0.7	-1.5	1.1	-0.1	-0.2	1.7	-0.1	-0.4	0.1	0.2	-0.4	-0.2	-0.2	-0.3	-0.5	-0.1	-0.1	-0.3
Depression (self-reported)	0.4	0.4	5.5	0.4	-0.1	0.3	2.3	0.4	-0.1	0.5	0.0	-0.5	-0.3	1.0	-0.2	0.1	0.0	0.6	0.1	0.1	-0.1	0.1
Medication: Lansoprazole	0.4	0.5	3.1	0.4	0.4	0.1	-1.8	-0.0	0.1	0.7	-0.2	0.6	-0.7	1.8	-0.0	-0.3	-0.0	-0.6	-0.5	-0.3	-0.1	-0.2
Impedance of arm (left)	0.4	1.7	10.6	-3.3	-0.7	1.7	-1.5	-0.6	-0.6	-2.6	-0.5	-0.8	-0.6	-2.6	0.1	-0.2	-0.5	0.1	0.2	-0.4	-0.6	-0.1
Peak expiratory flow (PEF)	0.4	0.9	3.1	-1.4	0.3	1.4	1.8	-1.3	-0.9	-0.5	-1.2	-0.9	0.2	0.2	0.0	-0.7	-0.9	0.4	0.7	-0.7	-1.3	-1.1
Blood clot in the leg (DVT)	0.4	0.5	2.8	-0.9	-0.2	-0.1	0.4	0.4	-0.7	-0.6	-0.8	-0.7	-1.7	0.4	-0.9	-0.8	-0.6	0.3	-0.2	-0.9	-0.1	-0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	3.0	-0.5	-0.5	-0.5	0.7	-1.2	-0.7	-1.7	-1.0	-0.6	0.4	0.2	-0.5	-0.9	-0.8	-1.0	-0.7	-0.9	-1.0	-1.0
Medication: Blood pressure	0.4	0.7	5.4	0.9	0.7	1.6	-1.5	0.1	0.2	-0.3	0.2	0.4	0.3	2.3	0.3	0.4	0.2	0.1	0.1	0.2	-0.2	0.3
Alcohol intake frequency.	0.4	0.9	2.5	-0.3	-1.0	-1.4	-1.6	-1.0	-0.7	0.0	-0.9	-0.6	-0.5	-1.4	-1.2	-1.1	-0.8	-1.2	-0.5	-1.0	-0.7	-1.1
Smoking status: Previous	0.4	0.6	2.6	0.1	-0.2	-1.6	-0.0	-0.4	-0.5	-1.2	-0.5	-1.0	-0.2	0.7	-0.4	-0.3	-0.4	-1.0	-1.4	-0.7	-1.3	-0.5
Back pain experienced in last month	0.4	0.6	5.2	-0.6	-0.2	-1.3	-0.0	-0.8	-0.5	-0.6	-0.3	-0.7	0.6	-2.3	-0.1	-0.1	-0.5	-0.2	0.4	-0.3	-0.7	-0.4
Osteoporosis (self-reported)	0.4	0.5	1.2	-0.1	-1.1	-0.5	-0.9	-0.6	-0.7	0.2	-0.6	-0.8	-0.8	1.0	-1.0	-0.6	-0.7	-0.6	-0.8	-0.3	-0.7	-0.7
Osteoarthritis (self-reported)	0.4	0.6	4.0	-0.9	-0.4	1.1	-2.0	0.5	-0.2	-1.7	-0.0	-0.1	-0.8	-0.6	0.0	-0.0	-0.2	0.1	0.1	-0.1	0.3	0.1
Medication: Gliclazide	0.4	0.4	2.1	0.6	0.5	-1.5	-0.1	0.7	0.7	1.3	0.5	0.4	0.4	0.8	0.2	0.3	0.7	-0.3	-0.2	0.6	0.3	0.3
Average weekly champagne plus white wine intake	0.4	0.6	3.3	-1.8	-0.5	0.0	0.3	-0.6	-0.4	-1.3	-0.2	-0.6	0.6	-1.8	0.3	0.1	-0.4	-0.4	0.1	-0.2	-0.9	-0.1
Commuting to job workplace: Public transport	0.4	0.4	1.4	0.1	-0.2	0.3	1.2	-0.1	-0.7	-0.5	-0.5	-0.9	-0.8	1.1	-0.8	-0.5	-0.7	-0.6	-0.9	-0.5	-0.5	-0.5
Medication: Atorvastatin	0.4	0.5	1.2	0.9	1.0	0.7	0.3	0.3	0.6	0.3	0.8	0.9	1.1	0.3	0.8	0.8	0.6	0.1	0.5	0.9	0.2	0.8
Illnesses of father: High blood pressure	0.4	0.5	1.8	0.0	0.2	0.9	-0.4	-0.0	0.6	-0.4	0.5	0.2	1.3	-1.1	0.9	0.9	0.7	0.7	1.1	0.6	0.0	0.6
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.6	-1.1	-0.3	-0.1	0.4	0.3	-0.7	-0.7	-0.8	-0.8	-1.6	0.2	-0.8	-0.7	-0.6	0.3	-0.2	-0.9	-0.3	-0.7
Bipolar Disorder or Schizophrenia	0.3	0.8	5.0	-1.2	0.2	2.2	-2.1	-0.1	-0.3	-1.1	-0.6	-0.1	-0.8	0.2	0.2	-0.3	-0.3	1.1	1.1	0.1	-0.2	-0.4
Crohns Disease (2017)	0.3	0.7	2.8	1.4	-0.0	-1.2	-1.2	-0.4	-0.0	1.7	-0.3	0.1	0.0	1.5	-0.4	-0.5	-0.1	-1.1	-1.0	-0.1	-0.3	-0.3
LDL Cholesterol	0.3	0.5	2.2	-0.4	-0.9	-1.5	1.3	0.2	-0.4	0.3	-0.2	-0.7	-0.7	-0.9	-1.0	-0.5	-0.4	-0.8	-0.7	-0.5	-0.0	-0.5
Lupus	0.3	0.4	2.1	-1.4	-0.3	-0.6	0.2	-0.1	-0.5	-0.3	-0.6	-0.8	-1.2	-0.9	-0.6	-0.6	-0.4	-0.3	-0.5	-0.6	-0.6	-0.5
Neuroticism (2016)	0.3	0.4	3.9	1.4	-0.1	-0.5	2.0	-0.2	0.2	0.9	0.2	0.4	0.7	0.0	0.2	0.2	0.2	0.2	0.4	0.4	-0.4	0.0
Rheumatoid Arthritis	0.3	0.4	1.3	-0.8	0.3	0.4	0.1	-0.5	-0.8	-1.2	-0.7	-0.7	-0.8	-0.3	-0.3	-0.3	-0.8	0.5	0.3	-0.6	-0.4	-0.5
Triglycerides	0.3	0.5	1.2	-0.3	0.7	0.6	0.6	0.8	0.8	0.5	0.8	1.0	0.6	-0.1	1.1	0.7	0.8	0.4	0.3	0.7	0.9	0.9
Type 2 Diabetes (T2D) (2012)	0.3	0.4	2.2	0.6	-0.6	-0.1	0.2	-0.5	-0.5	0.4	-0.6	-0.2	-0.3	1.5	-0.6	-0.6	-0.6	-0.5	-0.7	-0.4	-0.5	-0.7
Blood Red Count	0.3	3.1	7.0	2.6	1.8	-1.3	1.4	1.8	1.8	2.4	2.1	1.6	1.4	1.4	0.8	1.6	1.8	0.7	0.8	2.2	2.3	1.8
BMI	0.3	1.8	3.4	1.5	1.9	-1.2	0.3	1.3	1.5	1.6	1.5	1.2	1.5	-0.7	1.1	1.4	1.6	1.0	1.5	1.6	1.6	1.3
Waist Hip Ratio (WHR)	0.3	1.4	7.8	-1.1	-1.2	0.1	-2.8	-1.5	-1.2	-0.7	-1.1	-0.8	-0.4	-1.9	-0.8	-1.0	-1.3	-0.4	-0.1	-1.2	-0.9	-1.1
Respiratory disease	0.3	0.6	1.6	-1.0	0.0	0.0	0.2	-1.3	-0.9	0.3	-1.2	-0.9	0.1	-0.9	-0.7	-0.8	-1.0	0.0	0.5	-1.0	-1.0	-1.1
Frequency of depressed mood in last 2 weeks	0.3	0.5	3.5	0.1	-0.3	-1.4	1.9	-0.5	-0.2	0.3	-0.0	-0.4	0.3	-1.5	-0.0	0.2	-0.1	0.2	0.4	0.1	-0.5	-0.1
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	2.3	-0.1	-0.2	-0.4	1.5	-0.1	0.2	-0.2	0.3	-0.2	1.0	-0.6	0.6	0.6	0.4	0.2	0.1	0.3	-0.5	0.3
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.2	0.4	-0.6	-1.5	0.6	-0.7	-0.3	0.2	-0.3	-0.5	0.4	0.1	-0.2	-0.1	-0.1	-0.4	-0.5	-0.3	-0.9	-0.4
Multivitamins +/- minerals	0.3	0.4	1.7	0.9	0.6	0.5	-1.3	0.5	0.7	-0.1	0.5	0.9	0.6	0.2	0.7	0.5	0.6	0.4	0.4	0.7	0.6	0.5
Hearing difficulty/problems with background noise	0.3	0.5	1.5	0.3	1.0	-0.5	0.3	1.2	0.9	0.4	0.8	1.2	0.1	-0.8	0.5	0.4	0.9	0.1	0.3	0.7	1.2	0.7
Allergy	0.3	0.7	2.9	0.2	-1.7	-0.9	-0.8	-1.0	-0.6	-0.6	-0.6	-0.7	-0.1	-0.2	-0.6	-0.8	-0.7	-1.2	-1.1	-0.7	-0.9	-0.7
Weight	0.3	1.6	5.0	0.5	1.8	-0.3	-0.2	0.7	1.3	1.1	1.3	1.1	2.2	-1.5	1.3	1.5	1.3	1.0	1.4	1.4	1.0	1.2
Impedance of arm (right)	0.3	1.2	7.1	-2.7	-0.7	1.7	-1.6	-0.6	-0.5	-1.9	-0.4	-0.6	-0.7	-2.0	0.0	-0.2	-0.5	0.3	0.4	-0.3	-0.4	-0.1
Hair/balding pattern: Pattern 3	0.3	0.5	2.7	-0.4	-0.6	0.2	1.7	-0.1	-0.6	-0.2	-0.4	-0.8	-0.7	1.4	-0.4	-0.3	-0.5	-0.4	-0.9	-0.4	-0.8	-0.3
Happiness	0.3	0.3	2.5	-0.7	-0.3	0.3	1.6	0.6	0.0	0.0	0.4	-0.7	-0.2	-0.6	0.4	0.7	0.2	0.8	0.4	0.5	-0.1	0.5
Qualifications: A levels/AS levels or equivalent	0.3	0.7	5.2	1.7	0.1	0.2	1.2	1.0	0.1	0.7	0.3	-0.1	-1.1	2.3	-0.3	0.1	0.0	0.4	-0.5	0.3	0.6	0.2
Length of working week for main job	0.3	0.4	2.0	-0.2	0.3	-0.2	0.1	1.0	0.4	0.5	0.9	0.1	0.3	-1.4	0.3	0.7	0.5	0.3	0.1	0.5	0.9	0.9
Exposure to tobacco smoke at home	0.3	0.3	1.5	0.6	-0.4	-1.2	-1.2	-0.3	-0.3	0.1	-0.5	0.0	0.2	-0.6	-0.5	-0.7	-0.3	-0.2	-0.1	-0.6	0.0	-0.6
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.2	-1.1	-0.4	-0.2	0.2	0.1	-0.5	-1.1	-0.7	-0.6	-1.1	0.2	-0.6	-0.8	-0.5	-0.3	-0.6	-0.6	-0.5	-0.7
Birth weight	0.3	0.6	2.9	1.7	0.2	-0.9	0.6	-0.2	0.2	1.5	0.2	-0.0	1.2	1.4	0.2	0.4	0.3	0.2	0.1	0.4	-0.5	0.0
Wheeze or whistling in the chest in last year	0.3	0.5	1.5	0.5	-0.3	-0.6	-0.3	-0.8	-0.8	-0.0	-0.7	-0.3	-1.0	1.2	-1.0	-0.7	-0.9	-0.4	-0.3	-0.8	-0.4	-0.8
Number of children fathered	0.3	0.3	1.3	-0.9	0.3	-1.1	-1.1	0.0	-0.1	-0.5	-0.2	-0.1	0.2	-0.9	-0.1	-0.4	-0.1	-0.6	-0.5	-0.4	-0.1	-0.2
Emphysema/chronic bronchitis	0.3	0.4	2.1	0.9	-0.4	-1.3	1.5	-0.4	-0.2	0.5	-0.3	0.2	-0.3	-0.2	-0.7	-0.5	-0.3	-0.6	-0.3	-0.4	-0.0	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.0	-0.9	-0.8	-0.3	0.4	-0.0	-0.6	-0.6	-0.2	-0.8	-0.8	1.0	-0.1	-0.2	-0.5	-0.2	-0.7	0.1	-0.8	-0.2
Overall health rating	0.3	0.7	1.9	-0.7	0.7	0.5	1.4	0.2	0.4	-0.2	0.7	0.3	1.3	-1.2	1.2	1.2	0.6	0.9	1.2	0.8	-0.1	0.8
Family relationship satisfaction	0.3	0.3	2.0	-0.5	-0.2	-1.1	1.4	0.1	-0.3	-0.3	-0.1	-0.6	-0.7	-1.1	-0.6	-0.2	-0.2	0.0	0.0	-0.2	-0.1	-0.1
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.4	1.0	0.8	-1.2	0.5	0.5	0.3	0.6	0.5	0.3	0.3	-0.6	0.1	0.4	0.3	0.4	0.4	0.2	0.6	0.3
Medication for cholesterol	0.3	0.5	2.1	1.2	0.1	-0.1	1.1	-0.2	0.5	0.5	0.4	0.2	1.1	1.4	0.7	0.6	0.6	0.2	0.1	0.6	-0.4	0.4
Breast cancer (self-reported)	0.3	0.4	2.0	0.3	-0.7	0.2	-1.4	-0.5	-0.3	-0.8	-0.2	-0.5	0.7	1.3	0.4	0.1	-0.3	-0.0	-0.0	-0.0	-0.6	-0.1
Number of self-reported non-cancer illnesses	0.3	0.5	3.1	-0.8	0.3	1.7	0.3	-0.1	-0.1	-1.0	0.0	-0.2	0.5	-1.1	0.6	0.6	0.0	0.9	1.1	0.0	-0.4	0.2
Ever taken oral contraceptive pill	0.3	0.3	1.2	-0.7	-0.1	-1.1	-1.0	-0.1	-0.3	-1.1	-0.2	-0.9	-0.3	-0.9	-0.4	-0.0	-0.2	-0.1	0.1	-0.2	-0.5	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.4	0.1	0.6	1.2	-1.2	-0.1	0.3	-0.8	-0.3	0.7	-0.2	-0.6	-0.0	-0.5	0.1	0.1	0.7	-0.2	0.5	-0.3
Age started oral contraceptive pill	0.3	0.4	2.5	-0.1	-0.2	1.6	-0.3	0.2	-0.2	0.7	-0.1	0.0	-0.9	1.6	-0.3	-0.1	-0.2	0.1	-0.3	-0.1	0.1	0.1
Ever depressed for a whole week	0.3	0.4	1.9	-0.2	-0.0	1.4	-1.1	-0.1	0.1	-0.2	0.2	-0.3	0.8	-0.5	1.0	0.7	0.3	1.0	0.6	0.6	-0.9	0.3
Supplements: Calcium	0.3	0.4	0.9	0.4	0.3	0.9	-0.8	0.7	0.6	-0.1	0.7	0.7	0.6	0.1	0.6	0.7	0.6	0.6	-0.0	0.5	0.6	0.7
Depression (Nagel 2018)	0.2	0.3	2.1	0.5	0.3	-1.5	0.9	0.2	0.1	0.6	0.2	0.1	0.3	-0.3	0.2	0.4	0.2	0.5	0.9	0.4	0.3	0.1
Schizophrenia (2018)	0.2	0.5	2.6	-0.7	0.5	1.6	-1.4	0.8	0.1	-0.7	0.0	-0.0	-1.0	-0.2	0.3	0.2	0.2	1.2	0.8	0.2	0.4	0.2
Worry (Nagel 2018)	0.2	0.3	2.2	-0.4	0.1	1.5	1.3	0.4	0.1	0.3	0.2	-0.1	-0.3	-0.1	0.6	0.4	0.1	0.8	0.7	0.2	0.2	0.4
Alzheimer’s Disease (in father)	0.2	0.2	1.6	-0.3	-0.2	0.8	-0.3	-0.6	-0.5	-1.2	-0.3	-0.4	-0.3	-0.1	-0.3	-0.1	-0.6	0.1	0.1	-0.2	-0.7	-0.2
Irritable Bowel Disease (IBD)	0.2	0.5	2.8	1.4	0.2	-0.6	-0.9	-0.9	-0.3	1.7	-0.4	-0.1	0.5	1.0	-0.3	-0.4	-0.4	-0.6	-0.4	-0.1	-0.5	-0.5
Ulcerative Colitis (UC)	0.2	0.4	1.7	0.4	0.1	0.1	-0.1	-1.3	-0.8	1.2	-0.8	-0.6	0.2	-0.2	-0.6	-0.6	-0.8	-0.1	0.2	-0.5	-0.7	-0.9
Breast Cancer	0.2	0.5	1.6	0.2	-0.5	-0.9	-0.0	-0.0	-0.3	-1.3	-0.4	-0.2	-0.3	1.1	-0.6	-0.6	-0.3	-1.1	-1.2	-0.7	-0.2	-0.5
Crohns Disease (2012)	0.2	0.3	2.0	0.9	0.4	-0.2	-0.4	-0.4	0.1	1.3	-0.1	0.1	0.4	1.4	0.0	-0.0	0.1	-0.4	-0.4	0.0	-0.5	-0.1
Schizophrenia (2014)	0.2	0.4	1.8	-0.2	1.0	1.3	-0.9	0.8	0.3	-0.7	0.2	0.3	-0.7	0.3	0.4	0.2	0.4	0.9	0.6	0.3	0.3	0.3
Ulcerative Colitis	0.2	0.3	0.8	0.0	0.2	-0.5	0.6	-0.9	-0.7	0.4	-0.7	-0.7	0.1	-0.2	-0.6	-0.4	-0.7	-0.2	-0.2	-0.7	-0.6	-0.7
Systolic Blood Pressure	0.2	0.9	2.2	-0.6	-1.2	-0.6	0.2	-0.0	-1.0	-0.7	-0.7	-1.2	-1.5	1.4	-1.0	-0.6	-0.8	-0.5	-1.5	-1.1	-0.8	-0.8
Neuroticism	0.2	0.5	3.9	0.6	0.3	0.4	2.0	0.5	0.3	1.2	0.5	0.3	0.0	0.7	0.6	0.5	0.3	0.9	0.6	0.8	0.2	0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	2.2	1.5	0.2	0.3	0.3	0.5	0.3	0.8	0.4	0.4	-0.1	0.9	0.0	0.4	0.4	0.6	0.4	0.3	0.4	0.4
Systolic blood pressure, automated reading	0.2	0.5	1.2	0.3	-0.7	-0.9	0.0	-0.6	-0.6	0.2	-0.6	-0.8	-0.4	1.1	-0.6	-0.4	-0.6	-0.5	-0.9	-1.0	-1.0	-0.7
Severe depression (siblings)	0.2	0.3	3.0	-0.7	0.1	-0.2	-0.6	0.2	-0.0	-1.7	-0.1	-0.3	-0.3	-0.4	0.3	0.2	0.0	0.0	0.2	-0.2	-0.5	-0.0
Impedance of leg (right)	0.2	0.9	3.8	-1.9	0.1	1.9	-1.1	0.1	0.1	-0.2	0.3	-0.0	-0.1	-2.0	0.6	0.5	0.1	1.1	1.1	0.3	0.4	0.6
Fed-up feelings	0.2	0.4	4.8	-0.3	-0.5	-1.4	2.2	-0.0	-0.3	0.5	0.1	-0.5	-0.3	-0.4	0.1	0.3	-0.2	0.1	-0.2	0.3	-0.5	0.0
Relative age voice broke	0.2	0.3	1.2	-0.9	-0.6	1.1	-1.1	-0.8	-0.3	-0.2	-0.4	0.2	0.5	-0.3	0.1	-0.3	-0.4	0.1	0.3	-0.1	-0.1	-0.3
Medication: Levothyroxine sodium	0.2	0.3	2.8	0.8	0.4	-0.1	0.3	-0.7	0.3	-0.4	0.0	0.2	1.7	0.4	0.4	0.3	0.4	-0.1	0.4	0.1	-0.2	-0.0
Number of incorrect matches in round	0.2	0.3	2.2	0.9	-0.4	-0.2	-1.1	-0.7	-0.2	-0.5	-0.4	-0.4	0.1	1.5	-0.5	-0.4	-0.2	-0.3	-0.0	-0.3	-0.4	-0.5
Hair/balding pattern: Pattern 2	0.2	0.3	2.2	0.1	0.1	-0.2	-0.8	-0.5	-0.1	0.9	0.1	0.3	0.6	-1.5	-0.1	-0.1	-0.2	-0.2	0.5	0.3	0.3	-0.0
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.7	-0.7	-0.4	0.3	0.9	-0.1	-0.3	-0.2	-0.2	-0.7	0.1	-1.3	0.0	0.1	-0.1	0.4	0.3	-0.0	-0.8	-0.1
Neuroticism score	0.2	0.4	3.6	-0.0	-0.5	-0.7	1.9	0.3	0.1	0.7	0.6	-0.2	0.2	-0.5	0.5	0.6	0.3	0.6	0.2	0.8	-0.1	0.6
Alcohol intake versus 10 years previously	0.2	0.3	1.8	0.3	-0.0	-0.6	1.3	0.5	0.5	0.7	0.3	0.7	-0.3	0.0	0.1	0.0	0.4	-0.3	-0.1	0.2	0.8	0.2
Falls in the last year	0.2	0.3	1.0	1.0	0.3	-0.6	1.0	0.0	0.4	0.9	0.3	0.7	0.5	-0.5	0.2	0.3	0.4	0.3	0.5	0.2	0.2	0.1
Pulse rate	0.2	0.3	2.5	0.5	0.5	-1.6	-0.5	0.4	0.5	0.2	0.5	0.2	0.4	-0.3	0.2	0.4	0.6	-0.4	-0.3	0.4	0.2	0.3
Pulse wave Arterial Stiffness index	0.2	0.2	1.8	-0.2	-0.2	-1.3	-0.5	0.1	-0.1	-1.0	-0.0	-0.4	0.0	0.8	-0.3	-0.1	-0.0	-0.4	-0.8	-0.2	0.1	-0.1
Standing height	0.2	1.7	5.4	-1.7	-0.8	-1.0	-1.7	-2.3	-1.1	-1.0	-1.0	-1.4	1.6	-1.9	-0.2	-0.4	-1.0	-1.0	-0.5	-0.8	-2.2	-0.9
Breastfed as a baby	0.2	0.2	1.3	0.5	-0.3	1.1	-0.1	-0.3	0.2	-0.8	-0.0	0.7	0.1	0.6	0.3	-0.2	0.0	-0.2	-0.3	0.3	-0.0	0.1
Tense / ‘highly strung’	0.2	0.3	2.8	-1.0	-0.3	0.4	0.1	-0.5	-0.3	-0.4	-0.2	-0.2	-0.0	-1.7	0.0	-0.2	-0.3	0.1	0.4	-0.2	-0.1	-0.1
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.0	0.5	0.3	0.3	0.0	-0.2	0.4	0.9	0.3	0.5	1.0	-0.7	0.4	0.3	0.3	0.5	1.0	0.1	0.2	0.2
Medication: Paracetamol	0.2	0.3	2.0	0.2	-0.0	0.1	0.9	-1.1	-0.4	1.4	-0.1	-0.5	0.7	-0.3	0.3	0.3	-0.3	0.3	0.5	0.1	-0.8	-0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.9	-0.6	-0.1	0.2	-0.4	0.3	-0.5	-0.6	-0.4	0.0	-0.9	0.2	-0.5	-0.6	-0.6	-0.1	-0.3	-0.5	0.2	-0.4
High blood pressure (siblings)	0.2	0.4	2.0	-0.3	-0.4	-0.8	1.4	-0.8	-0.4	-0.5	-0.5	-0.6	0.3	-0.9	-0.3	-0.2	-0.3	0.1	0.4	-0.5	-0.6	-0.5
Comparative body size at age 10	0.2	0.6	3.8	0.5	-0.5	-2.0	0.6	0.2	-0.5	-0.3	-0.3	-0.7	-1.1	1.4	-0.9	-0.5	-0.4	-0.6	-0.7	0.1	-0.3	-0.5
Pulse wave peak to peak time	0.2	0.3	1.6	0.0	0.2	1.3	0.4	-0.3	-0.0	0.9	-0.0	0.3	0.0	-1.1	0.3	0.1	-0.1	0.4	0.9	0.2	-0.2	0.0
Qualifications: College or University degree	0.2	0.5	4.1	0.5	-0.1	1.0	-2.0	0.4	0.2	-1.5	0.5	0.1	0.2	0.0	0.3	0.2	0.1	-0.4	-0.7	0.6	0.3	0.6
Medication for pain relief, constipation, heartburn	0.2	0.3	2.6	1.0	0.1	0.6	0.1	0.9	0.3	-0.0	0.3	0.5	-0.6	1.6	-0.2	-0.0	0.3	0.1	-0.2	0.1	0.8	0.2
Arm predicted mass (right)	0.2	0.9	4.5	1.3	1.0	-1.7	0.5	-0.1	0.6	1.7	0.6	0.5	2.1	-0.4	0.6	0.8	0.6	0.2	0.5	0.8	0.1	0.4
Comparative height size at age 10	0.2	1.1	12.0	-0.9	0.5	-0.5	-3.5	-0.9	-0.2	-0.5	-0.2	-0.2	1.4	-1.6	-0.1	0.1	-0.2	-0.4	0.6	0.0	-0.6	-0.2
Chest pain or discomfort	0.2	0.3	1.2	-0.3	-0.5	0.2	-0.8	-0.4	-0.6	-1.1	-0.6	-0.7	-0.6	0.4	-0.7	-0.6	-0.6	-0.1	0.1	-0.5	-0.2	-0.6
Had major operations	0.2	0.3	1.5	0.5	-0.7	0.2	-0.2	-1.2	-0.5	-0.2	-0.5	0.0	0.7	-0.5	-0.3	-0.5	-0.6	-0.8	-0.2	-0.2	-0.6	-0.5
Knee pain experienced in last month	0.2	0.3	1.3	-0.7	-0.8	-0.7	-0.9	0.0	-0.3	-1.1	-0.3	-0.3	-0.6	-0.1	-0.5	-0.4	-0.2	-0.8	-0.8	-0.5	-0.2	-0.3
Illnesses of father: Heart disease	0.2	0.3	1.6	-0.8	0.3	1.3	0.8	0.9	0.0	0.7	0.1	-0.3	-0.8	0.8	0.1	0.3	0.1	0.6	0.2	0.3	0.1	0.2
Mineral and other dietary supplements	0.2	0.3	1.4	1.0	-0.5	-1.2	0.7	-0.4	0.0	0.2	0.4	-0.1	1.0	-0.9	-0.1	0.3	0.1	-0.7	-0.2	0.4	-0.2	0.2
Medication: Aspirin	0.2	0.3	0.7	-0.8	-0.2	-0.4	-0.3	-0.4	-0.4	-0.7	-0.5	-0.5	-0.6	-0.9	-0.6	-0.6	-0.4	-0.6	-0.4	-0.5	-0.4	-0.5
Miserableness	0.2	0.4	2.2	-0.5	-0.6	-1.5	0.8	-0.1	-0.5	1.4	0.0	-0.6	-0.4	-0.3	-0.1	0.2	-0.4	0.7	0.4	0.5	-0.3	-0.0
Tinnitus: Yes, now most or all of the time	0.2	0.2	2.9	0.0	0.1	-0.0	-0.5	0.6	0.3	-0.4	0.2	0.1	-0.2	1.7	0.0	0.1	0.3	-0.4	-0.7	-0.0	0.1	0.2
Medication: Paracetamol	0.2	0.3	1.7	-0.0	-0.3	-0.2	0.5	-1.2	-0.5	1.3	-0.3	-0.4	0.4	-0.8	0.1	0.1	-0.4	-0.3	0.0	-0.3	-0.8	-0.3
Ever smoked	0.2	0.4	1.8	1.4	0.6	-1.0	0.9	0.3	0.6	-0.5	0.5	0.3	0.8	0.8	0.3	0.6	0.6	0.2	0.0	0.4	0.3	0.4
Arm fat-free mass (left)	0.2	1.0	4.4	1.4	1.1	-1.5	0.2	0.1	0.8	2.0	0.8	0.6	2.1	-0.3	0.7	0.9	0.8	0.4	0.7	0.9	0.3	0.5
Commuting to job workplace: Cycle	0.2	0.3	1.0	1.0	-0.1	-0.1	0.5	-0.6	-0.2	0.1	-0.3	0.1	0.1	0.8	-0.1	-0.4	-0.3	-0.8	-0.8	-0.5	-0.7	-0.4
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.7	0.7	0.7	0.5	-0.4	0.5	0.6	0.7	0.6	0.5	0.9	0.1	0.6	0.6	0.6	1.2	1.3	0.8	0.8	0.6
Cholesterol lowering medication	0.2	0.3	3.9	-0.7	0.2	0.8	-0.5	-0.3	-0.2	0.2	0.0	-0.0	0.5	-2.0	-0.0	0.0	-0.3	0.0	0.2	0.1	0.4	0.1
Basal cell carcinoma (self-reported)	0.2	0.3	0.7	-0.3	-0.5	-0.9	-0.2	-0.8	-0.4	-0.0	-0.8	-0.2	0.1	0.1	-0.5	-0.7	-0.4	-0.4	-0.1	-0.5	-0.7	-0.9
Impedance of whole body	0.2	1.2	7.8	-2.8	-0.4	2.2	-1.1	-0.2	-0.2	-1.5	-0.1	-0.5	-0.4	-2.1	0.4	0.2	-0.2	0.6	0.7	0.0	-0.0	0.3
Arm predicted mass (left)	0.2	1.1	5.3	1.5	1.2	-1.4	0.3	0.0	0.8	2.0	0.9	0.6	2.3	-0.3	0.8	1.0	0.9	0.4	0.7	1.0	0.2	0.6
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.2	-0.9	0.8	0.8	-1.1	1.0	-0.1	-0.6	0.1	-0.2	-0.8	-0.7	0.1	0.3	0.0	1.0	0.4	0.1	0.3	0.2
Major Depression (MDD)	0.1	0.1	1.1	-0.5	-0.1	-0.4	-0.6	0.1	-0.1	-0.1	-0.1	-0.1	-0.3	-1.1	-0.4	-0.2	-0.1	-0.3	-0.1	-0.3	0.2	-0.1
Reaction Time	0.1	0.2	1.1	-0.3	-0.1	0.8	0.9	0.3	-0.0	-0.2	0.4	0.0	-0.3	-1.0	0.2	0.4	-0.0	0.7	0.7	0.3	0.4	0.4
Body Mass Index (BMI) (2010)	0.1	0.1	1.0	0.5	0.2	-0.1	0.2	0.3	0.3	0.4	0.3	-0.1	0.1	1.0	0.3	0.4	0.4	0.2	-0.2	0.2	-0.2	0.3
Blood Eosinophil Count	0.1	0.8	2.5	0.6	-0.7	0.0	-1.6	-1.0	-1.1	1.0	-0.9	-0.6	-1.3	-0.2	-1.3	-0.9	-1.2	-0.5	-0.5	-0.9	-0.8	-0.9
Blood White Count	0.1	0.5	1.4	1.0	0.1	0.1	-1.0	0.9	0.7	1.2	0.7	0.9	0.1	0.2	0.2	0.4	0.6	0.3	0.5	0.7	1.1	0.6
Heel T-Score	0.1	0.4	2.4	-1.1	-0.2	1.6	-0.9	-0.1	-0.1	-0.2	-0.1	-0.0	0.4	0.9	0.7	0.3	-0.1	1.0	0.9	-0.0	-0.1	-0.0
Height	0.1	1.1	4.8	-1.5	-0.1	-0.5	-1.6	-1.8	-0.6	-0.8	-0.4	-0.7	2.2	-1.4	0.5	0.3	-0.5	-0.2	0.4	-0.5	-1.6	-0.4
Allergy or Eczema	0.1	0.3	1.2	-1.1	0.9	0.3	0.3	0.9	0.2	0.5	0.4	0.3	-0.7	-0.6	0.0	0.2	0.2	0.4	0.6	0.5	1.1	0.5
Cardiovascular Disease	0.1	0.2	1.2	-0.9	-0.1	-0.6	-0.1	-0.2	-0.1	-0.6	-0.2	-0.4	-0.1	-1.1	-0.2	-0.1	-0.0	-0.5	-0.5	-0.3	-0.2	-0.1
Hand grip strength (left)	0.1	0.3	2.8	0.7	-0.0	-0.5	-0.1	-0.2	-0.0	1.7	-0.1	-0.0	0.5	0.4	-0.1	-0.0	-0.0	0.8	0.5	0.4	0.1	-0.1
Hearing difficulty/problems: Yes	0.1	0.2	0.3	-0.5	0.4	-0.5	-0.4	0.6	0.5	-0.1	0.5	0.5	0.4	-0.2	0.5	0.3	0.5	-0.0	-0.2	0.4	0.3	0.5
Leg fat-free mass (left)	0.1	0.4	2.4	0.5	0.6	-1.2	-0.1	-0.3	0.3	0.7	0.3	0.2	1.6	-1.1	0.4	0.4	0.3	-0.0	0.4	0.5	-0.0	0.2
Hand grip strength (right)	0.1	0.3	1.4	0.3	0.1	-0.9	0.6	-0.6	-0.5	1.2	-0.6	-0.5	0.2	1.0	-0.4	-0.4	-0.4	0.3	-0.0	-0.2	-0.5	-0.7
High blood pressure	0.1	0.3	1.3	-0.8	-0.4	-0.5	0.1	-0.1	-0.3	-0.5	-0.3	-0.2	-0.9	-0.2	-0.4	-0.4	-0.2	-1.0	-1.1	-0.5	-0.4	-0.3
Sitting height	0.1	0.7	2.9	-0.1	-0.0	-0.9	-0.8	-1.5	-0.7	1.1	-0.7	-1.1	1.0	0.2	-0.5	-0.4	-0.7	-1.0	-0.7	-0.5	-1.7	-0.8
Impedance of leg (left)	0.1	0.7	3.3	-1.7	-0.2	1.8	-1.1	0.2	0.0	-0.0	0.3	-0.1	-0.2	-1.6	0.4	0.4	0.0	0.9	0.9	0.3	0.5	0.5
Leg predicted mass (left)	0.1	0.4	2.5	0.4	0.7	-1.3	-0.0	-0.3	0.3	0.7	0.4	0.3	1.6	-1.2	0.4	0.4	0.3	-0.0	0.4	0.5	-0.0	0.2
Past tobacco smoking	0.1	0.3	1.6	-0.8	-0.1	1.3	-0.8	0.2	0.0	0.3	-0.0	0.3	-0.4	-0.9	0.1	-0.2	-0.1	0.3	0.7	0.1	0.5	0.1
Nervous feelings	0.1	0.3	1.6	-0.4	-0.6	-0.3	-0.4	0.1	-0.4	-0.4	-0.5	-0.6	-1.3	0.3	-0.6	-0.6	-0.5	-0.2	-0.5	-0.6	-0.2	-0.4
Medication: Ramipril	0.1	0.2	0.6	-0.3	-0.1	-0.7	-0.5	-0.2	-0.2	0.4	-0.4	-0.2	-0.4	0.8	-0.6	-0.6	-0.3	-0.4	-0.4	-0.2	-0.2	-0.5
Trunk fat-free mass	0.1	0.7	4.5	1.3	0.5	-2.1	0.3	-0.6	0.2	1.6	0.2	0.1	2.0	-0.4	0.2	0.4	0.2	-0.2	0.1	0.3	-0.6	-0.1
Father’s age at death	0.1	0.1	1.0	0.2	-0.2	-0.2	0.0	-0.5	-0.0	-0.0	0.1	-0.3	1.0	-0.6	0.5	0.3	0.0	0.3	0.3	0.3	-0.3	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.7	-0.8	0.7	0.9	1.3	-0.5	-0.3	0.4	-0.5	-0.5	0.3	-0.2	0.3	-0.0	-0.2	1.1	1.2	-0.1	-0.7	-0.4
Asthma	0.1	0.2	1.1	-0.4	1.1	0.2	0.7	-0.3	-0.0	0.3	-0.2	0.0	0.4	-0.4	0.1	0.1	-0.0	0.6	1.0	-0.2	-0.3	-0.2
Illnesses of mother	0.1	0.2	0.6	-0.8	-0.4	-0.8	-0.4	0.1	0.1	-0.7	-0.1	-0.3	0.1	-0.6	0.3	0.0	0.2	-0.5	-0.2	0.1	-0.3	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.3	-0.7	0.7	1.5	0.4	-0.6	-0.2	-0.1	-0.4	-0.5	0.5	-0.1	0.4	0.2	-0.1	1.2	1.3	0.1	-0.7	-0.2
Trunk predicted mass	0.1	0.8	4.3	1.2	0.6	-2.1	0.3	-0.6	0.2	1.5	0.2	0.1	2.1	-0.4	0.3	0.4	0.3	-0.2	0.1	0.3	-0.6	-0.1
Hair/balding pattern: Pattern 4	0.1	0.3	0.7	0.2	0.8	-0.5	-0.7	0.8	0.5	-0.2	0.5	0.3	0.1	-0.1	0.5	0.5	0.6	0.6	0.4	0.5	0.6	0.5
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.6	-0.1	-0.2	0.8	0.4	-0.1	-0.0	-0.4	0.1	0.3	0.1	0.0	0.4	0.1	-0.1	-0.1	0.1	0.1	0.1	0.2
Arm fat-free mass (right)	0.1	0.7	4.1	1.3	0.8	-1.5	0.5	-0.4	0.4	1.6	0.4	0.3	2.0	-0.2	0.4	0.6	0.4	0.0	0.4	0.6	-0.1	0.2
Worry too long after embarrassment	0.1	0.2	1.0	-0.4	-0.7	-1.0	0.1	-0.2	-0.6	0.0	-0.2	-0.7	-0.8	-0.3	-0.4	-0.2	-0.5	-0.1	-0.3	-0.0	-0.5	-0.3
Migraine (self-reported)	0.1	0.1	1.1	-0.6	0.5	0.6	-0.1	0.0	-0.1	0.1	-0.2	0.1	-0.3	-1.0	0.1	-0.1	-0.1	0.1	0.6	-0.1	0.1	-0.1
Medication: Ibuprofen	0.1	0.1	1.0	-0.4	-0.0	-0.2	-1.0	-0.4	-0.1	0.3	-0.0	-0.1	0.6	-0.8	0.2	0.1	-0.1	0.1	0.2	-0.0	-0.2	-0.1
Pulse rate, automated reading	0.1	0.3	1.8	-0.3	0.4	-0.8	-1.1	0.4	0.3	0.4	0.3	0.3	0.1	-1.3	0.2	0.1	0.3	-0.3	0.2	0.1	0.5	0.2
Medication: Aspirin	0.1	0.1	0.5	-0.4	0.4	-0.0	-0.4	0.1	-0.0	-0.1	-0.1	-0.0	-0.6	-0.7	-0.4	-0.3	-0.1	-0.2	0.0	-0.0	0.2	-0.1
Whole body fat-free mass	0.1	0.6	3.3	1.0	0.5	-1.8	0.1	-0.5	0.2	1.2	0.2	0.1	1.8	-0.5	0.2	0.3	0.2	-0.2	0.2	0.3	-0.4	-0.0
Leg fat-free mass (right)	0.1	0.3	2.0	0.6	0.3	-1.3	0.0	-0.4	0.1	0.7	0.2	0.1	1.4	-0.7	0.2	0.2	0.1	-0.2	0.2	0.4	-0.2	0.0
Long-standing illness, disability or infirmity	0.1	0.2	1.0	-1.0	0.3	-0.4	0.4	-0.2	-0.5	0.4	-0.3	-0.5	-0.6	-0.3	0.0	0.0	-0.3	0.6	0.4	-0.3	-0.7	-0.3
Asthma (self-reported)	0.1	0.2	1.2	-0.3	1.0	0.4	0.3	-0.2	0.1	0.4	-0.1	0.2	0.6	-0.4	0.2	0.2	0.1	0.6	1.1	-0.1	-0.1	-0.1
Illnesses of father: None of the above (group 1)	0.1	0.2	1.2	-0.3	-0.3	0.2	-0.5	0.1	-0.3	-0.3	-0.4	-0.1	-1.1	0.5	-0.4	-0.5	-0.4	-0.3	-0.3	-0.4	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.9	-0.7	-0.1	0.4	-0.3	0.1	-0.4	0.2	-0.6	-0.6	-1.0	-0.0	-0.6	-0.8	-0.4	-0.1	-0.2	-0.4	-0.2	-0.6
Whole body water mass	0.1	0.6	3.5	1.0	0.6	-1.8	0.1	-0.5	0.3	1.3	0.3	0.2	1.9	-0.6	0.3	0.4	0.3	-0.1	0.3	0.4	-0.3	0.1
Leg predicted mass (right)	0.1	0.3	2.0	0.6	0.4	-1.4	-0.0	-0.4	0.1	0.7	0.2	0.1	1.4	-0.8	0.2	0.2	0.2	-0.2	0.2	0.4	-0.2	0.0
Guilty feelings	0.1	0.2	1.6	0.6	-0.1	0.1	0.8	-0.1	0.1	1.2	0.1	0.1	0.2	0.3	0.3	0.2	0.1	0.5	0.4	0.5	-0.1	0.1
Mother’s age at death	0.1	0.2	0.9	-0.4	0.4	0.1	-0.7	-0.4	-0.1	-0.9	0.1	-0.3	0.4	-0.3	0.4	0.4	-0.1	0.4	0.4	0.2	-0.4	0.2
Pain type(s) experienced in last month: Hip pain	0.1	0.2	1.5	-0.8	-0.2	-0.6	-0.2	0.1	0.1	-0.5	-0.0	-0.2	0.2	-1.2	0.1	0.0	0.2	-0.3	0.0	-0.0	-0.1	-0.0
Medication: Bendroflumethiazide	0.1	0.2	1.2	0.1	0.5	1.1	0.6	0.0	0.2	0.1	0.0	0.2	0.1	0.7	0.3	0.3	0.3	0.3	0.3	-0.0	-0.5	0.1
Basal metabolic rate	0.1	0.7	4.3	0.9	0.9	-1.4	0.1	-0.2	0.6	1.4	0.6	0.4	2.1	-0.9	0.6	0.7	0.6	0.2	0.6	0.7	0.0	0.4
Diastolic blood pressure, automated reading	0.1	0.3	1.5	1.0	0.4	-1.2	0.6	-0.1	0.4	1.2	0.2	0.1	1.0	0.4	0.1	0.3	0.4	0.1	0.0	0.1	0.1	0.1
Unable to work because of sickness or disability	0.1	0.2	1.4	0.4	-0.1	0.5	0.4	-0.1	0.1	0.3	0.2	0.5	0.2	-1.2	-0.1	0.1	-0.0	0.3	0.6	0.1	0.4	0.1
Pain experienced in last month	0.1	0.2	1.4	0.5	0.3	0.5	1.2	-0.0	0.2	1.1	0.1	0.5	-0.3	0.9	-0.3	-0.1	0.1	-0.1	-0.1	0.2	0.4	0.1
Blood Platelet Count	0.0	0.5	3.4	-0.4	0.3	-0.3	-1.8	-0.9	-0.2	-0.5	-0.3	-0.2	1.2	-1.8	-0.1	-0.1	-0.2	-0.3	0.4	-0.2	-0.6	-0.4
Hair Pigment	0.0	0.4	1.7	-0.1	1.3	0.4	-0.7	-0.2	0.3	0.5	0.5	0.1	0.7	0.1	1.1	0.8	0.4	0.5	0.7	0.5	-0.4	0.5
Tanning	0.0	0.3	2.4	-0.3	-0.7	-1.6	-0.7	0.2	-0.3	0.1	-0.3	-0.4	-0.9	0.3	-0.7	-0.5	-0.3	-0.1	-0.4	-0.1	0.0	-0.4
Sensitivity / hurt feelings	0.0	0.1	0.3	0.1	-0.5	-0.3	0.3	-0.1	-0.0	-0.3	0.1	-0.2	0.0	0.4	-0.1	0.0	0.0	-0.3	-0.4	-0.1	-0.4	0.0
Mean time to correctly identify matches	0.0	0.1	0.6	0.0	-0.3	0.5	-0.2	0.1	-0.2	-0.7	0.1	-0.1	-0.8	0.1	-0.1	0.2	-0.2	-0.1	-0.1	-0.1	-0.1	0.2
Hypertension (Self-reported)	0.0	0.1	0.5	-0.5	-0.1	-0.6	-0.0	0.1	0.0	-0.5	0.1	0.0	-0.5	-0.2	-0.0	-0.0	0.1	-0.6	-0.7	-0.1	-0.2	0.0

Hub : Genes

SPATA9

Models

Trait associations