Hub : Genes

SRPRB

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0800 0.0230 1.4e-05 0.062 0.045 0.044 0.047 0.055 5.4e-08 3.3e-06 3.6e-06 2.2e-06 3.0e-07
2 GTEx Esophagus Mucosa 0.4550 0.0530 0.0e+00 0.197 NA 0.346 NA 0.358 3.1e-13 NA 6.4e-24 NA 6.9e-25
3 GTEx Esophagus Muscularis 0.1360 0.0550 8.5e-03 -0.005 NA -0.002 NA -0.005 9.5e-01 NA 4.4e-01 NA 9.8e-01
4 GTEx Skin Not Sun Exposed Suprapubic 0.1830 0.0500 1.3e-05 0.126 NA 0.099 NA 0.124 2.2e-07 NA 4.4e-06 NA 2.8e-07
5 GTEx Skin Sun Exposed Lower leg 0.1150 0.0300 3.5e-06 0.116 NA 0.085 NA 0.101 7.5e-10 NA 1.5e-07 NA 9.9e-09
6 YFS Blood 0.1640 0.0234 0.0e+00 0.116 0.181 0.198 0.199 0.200 6.2e-36 8.0e-57 8.6e-63 5.2e-63 2.2e-63
7 TCGA Lung Squamous Cell Carcinoma 0.0765 0.0498 9.3e-03 0.002 0.015 0.012 NA 0.005 1.7e-01 7.0e-03 1.5e-02 NA 7.2e-02
8 TCGA Testicular Germ Cell Tumors 0.2370 0.0900 5.3e-04 0.053 0.097 0.078 NA 0.082 6.1e-03 2.8e-04 1.1e-03 NA 7.5e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.9 2.0 0.7 -1.4 -0.7 -1.3 -1.1 -0.7 0.2 0.5
Bipolar Disorder or Schizophrenia 0.6 1.5 4.2 2.0 -1.4 -0.7 -0.2 -0.3 -2.1 0.4 1.3
Depressed Affect (Nagel 2018) 0.2 0.5 1.3 1.0 -0.0 1.1 -0.6 -0.4 -0.3 0.9 0.3
Depression (Nagel 2018) 0.2 0.3 0.5 0.7 -0.7 0.6 -0.7 -0.0 -0.2 -0.1 -0.5
Intelligence (Savage-Jansen 2018) 0.5 1.5 3.1 -1.4 1.2 1.8 1.3 1.1 1.4 0.4 0.5
Neuroticism (Nagel 2018) 0.2 0.6 2.2 0.9 0.1 0.8 -0.8 -0.2 0.1 1.5 0.1
Schizophrenia (2018) 0.7 1.4 4.3 2.0 -0.6 -0.2 0.8 0.5 -2.1 0.3 1.1
Schizophrenia vs Biploar Disorder 0.5 0.6 2.3 0.6 -0.3 -0.3 -0.8 -0.3 -0.2 -1.2 -1.5
Worry (Nagel 2018) 0.2 0.4 1.7 -0.0 0.4 -0.1 -0.5 -0.2 1.1 1.3 -0.1
Alzheimer’s Disease (in mother) 1.0 1.2 3.3 0.5 -1.8 1.0 -1.4 -1.5 0.4 -0.4 -0.8
Alzheimer’s Disease (in father) 2.1 2.2 4.0 -0.3 1.9 1.7 1.8 2.0 1.4 1.4 -0.1
Alzheimer’s Disease (including proxy) 0.5 0.7 4.7 0.4 -0.5 2.2 -0.1 -0.1 0.5 0.2 -0.6
Crohns Disease (2017) 0.8 1.7 3.6 0.3 -1.3 -0.8 -1.4 -1.9 -1.2 -1.6 -1.3
Irritable Bowel Disease (IBD) 0.9 2.3 3.8 1.2 -1.4 -0.6 -1.5 -1.8 -2.0 -1.5 -1.6
Ulcerative Colitis (UC) 0.5 1.0 2.2 1.3 -0.7 0.1 -1.1 -0.9 -1.5 -0.5 -1.0
Major Depression (MDD) 0.3 0.3 1.8 -1.4 0.5 -0.4 0.0 -0.0 0.3 -0.5 -0.3
Reaction Time 0.2 0.3 0.9 -0.3 0.9 -0.7 0.4 0.7 0.2 0.5 -0.2
Verbal and Numeric Reasoning (VNR) 0.7 1.6 9.1 -0.4 1.1 3.0 0.6 0.8 0.7 0.7 0.5
Breast Cancer 1.3 3.1 5.3 0.2 -2.0 -0.7 -1.9 -2.3 -0.9 -2.2 -2.3
Ovarian Cancer 0.3 0.4 1.4 0.5 -0.6 -0.4 -0.5 -0.1 -0.0 -1.0 -1.2
Prostate Cancer 0.4 0.6 1.8 1.4 0.4 0.9 0.7 0.0 -1.2 -0.1 -0.2
Age at First Birth 0.8 1.1 4.0 2.0 -1.3 0.7 -0.5 -0.5 -1.2 -0.4 -1.0
Bipolar Disorder (2011) 4.4 4.3 9.7 2.4 -3.1 1.2 -2.6 -2.5 -2.1 -0.1 -0.1
Body Mass Index (BMI) (2010) 1.3 1.8 4.7 1.1 -0.6 -1.2 -1.2 -0.8 -2.2 -1.5 -1.4
Coronary Artery Disease (CAD) 0.8 1.0 3.1 -1.8 1.1 -0.5 0.5 0.3 1.7 -0.4 0.4
Crohns Disease (2012) 2.2 3.5 6.1 0.4 -2.4 -1.2 -2.0 -2.4 -1.1 -2.5 -1.8
Mean Putamen Volume 0.7 0.8 3.6 1.9 -0.5 0.7 -0.8 -0.1 -1.1 0.3 -0.5
Fasting Glucose 0.6 0.7 1.5 0.8 -0.3 -0.1 -1.1 -1.1 -1.2 0.1 -0.7
HbA1C 3.1 3.4 9.3 -0.3 -0.7 -1.5 -1.8 -1.8 -0.8 -3.1 -2.8
HDL Cholesterol 0.2 0.3 0.8 -0.9 0.5 -0.6 0.5 0.6 0.3 -0.1 -0.0
LDL Cholesterol 0.3 0.5 1.4 0.4 0.2 1.2 0.5 0.7 -0.2 1.0 0.6
Lupus 0.4 0.6 2.0 -0.2 0.6 -0.0 1.2 1.4 0.7 0.4 -0.4
Neuroticism (2016) 0.6 0.9 3.3 -0.5 1.2 1.1 -0.2 -0.2 0.8 -0.8 -1.8
Primary Biliary Cirrhosis 0.3 0.4 1.3 0.7 -0.8 0.5 -0.7 -0.2 -0.5 1.2 0.1
Rheumatoid Arthritis 0.3 0.4 1.1 -0.4 -0.7 0.6 -0.0 -0.2 0.9 1.0 0.8
Schizophrenia (2014) 1.1 2.4 8.2 2.3 -1.9 -0.5 -0.9 -1.0 -2.9 -0.4 0.3
Triglycerides 0.4 0.7 2.1 0.2 1.0 0.4 0.9 1.4 -0.1 0.8 0.8
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.6 0.7 -0.8 -0.0 -0.3 -0.3 -0.2 -0.3 0.1
Ulcerative Colitis 0.3 0.4 1.7 1.1 -0.3 -0.4 -0.1 -0.1 -1.3 -0.3 -0.2
Blood Eosinophil Count 0.4 2.8 6.5 1.7 -2.5 1.0 -2.1 -2.0 -1.0 -0.1 -1.6
Blood Platelet Count 0.2 2.7 5.5 1.6 -1.4 1.2 -2.3 -1.9 -0.5 -1.0 -2.3
Blood Red Count 1.8 17.2 55.2 0.6 -4.0 -3.5 -3.7 -7.4 -3.7 -3.9 -3.3
Blood White Count 0.1 0.6 1.1 1.1 -1.1 -1.0 -0.9 -0.6 -0.7 0.4 -0.0
Heel T-Score 0.4 3.3 10.6 -1.9 -1.0 -3.3 -1.8 -1.6 0.5 -2.1 -0.9
BMI 0.1 0.5 1.2 0.9 0.2 0.2 1.1 1.0 -0.8 0.7 0.4
Height 0.1 1.9 4.6 -0.3 1.7 -0.6 2.0 1.6 0.6 2.1 0.4
Waist Hip Ratio (WHR) 0.2 0.8 1.8 0.9 -0.5 0.1 -0.4 -0.7 -1.3 -1.3 -1.1
Systolic Blood Pressure 0.6 3.0 6.2 1.7 -1.5 -1.6 -1.2 -1.1 -2.5 -2.2 -1.6
Smoking Status 0.0 0.1 0.3 -0.2 0.4 -0.3 0.2 -0.1 -0.5 -0.3 -0.2
Allergy or Eczema 0.2 0.5 1.1 -0.4 -0.6 0.8 -1.1 -0.9 0.7 -0.1 -0.1
Cardiovascular Disease 0.4 1.4 5.4 2.3 -0.2 1.8 0.5 0.5 -1.2 0.6 0.2
Hypothyroidism (self reported) 0.6 1.5 3.7 -1.4 0.5 1.9 0.6 0.8 1.7 1.2 0.7
Respiratory disease 0.3 0.7 1.7 -1.2 0.6 1.3 0.6 -0.3 1.0 0.7 0.3
Type 2 Diabetes (T2D) (2018) 1.2 2.2 4.6 0.1 1.4 1.1 1.5 2.1 1.6 1.6 1.5
Lung FEV1/FVC ratio 0.1 0.6 1.7 0.5 -0.4 -1.3 -0.6 -0.9 -0.6 -0.5 -0.8
Lung FVC 1.0 5.3 9.2 -1.8 2.9 1.5 2.4 2.9 3.0 1.7 1.3
Neuroticism 0.3 0.7 1.7 0.1 0.1 0.1 -1.3 -0.8 1.1 1.3 -0.3
Chronotype (morning person) 0.2 0.5 1.7 -0.2 0.6 -0.9 0.1 0.6 0.7 1.3 0.4
Hair Pigment 0.1 2.1 5.4 -0.5 1.5 0.9 0.7 1.9 1.1 2.3 1.7
Tanning 0.2 2.3 7.5 -1.2 -0.5 -1.3 -1.0 -1.7 0.4 -2.0 -2.7
Hand grip strength (left) 0.9 2.3 6.6 -1.9 1.5 -2.6 1.7 1.2 0.1 -1.0 0.7
Number of treatments/medications taken 0.4 0.7 2.8 0.7 -0.2 1.4 0.2 0.3 -0.1 1.7 0.7
Average weekly spirits intake 0.8 1.0 3.1 0.7 -0.4 0.7 -0.7 -0.7 -0.1 -1.5 -1.8
Sensitivity / hurt feelings 0.4 0.8 1.9 1.3 -0.7 1.4 -0.4 -0.6 -0.9 0.3 -0.7
Frequency of depressed mood in last 2 weeks 0.2 0.3 0.9 -1.0 0.2 -0.8 -0.6 0.1 0.4 -0.1 -0.0
Hearing difficulty/problems: Yes 0.2 0.3 0.7 -0.5 0.7 0.8 0.5 -0.3 0.7 0.4 0.3
Relative age of first facial hair 0.3 0.6 1.6 1.3 -0.5 0.9 -0.4 -0.6 -1.0 0.1 -0.4
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 2.0 -0.1 0.8 0.5 0.2 0.3 0.8 1.4 0.0
Ever used hormone-replacement therapy (HRT) 0.2 0.3 0.9 -0.0 -0.3 -0.9 -0.7 -0.2 0.6 -0.3 -0.7
Ever had hysterectomy (womb removed) 2.2 2.5 4.6 -1.5 2.1 -0.9 1.4 2.2 1.3 1.1 1.8
Systolic blood pressure, automated reading 0.9 2.6 4.8 1.6 -2.2 -0.4 -1.0 -1.4 -2.1 -2.1 -1.1
Eye problems/disorders: Diabetes related eye disease 0.9 1.0 3.3 1.8 -0.8 0.5 -0.5 -0.9 -1.4 0.7 -0.7
Angina 0.2 0.2 1.3 0.7 -0.1 0.2 -0.0 0.2 -1.2 -0.1 0.1
Medication for hormone replacement therapy 1.0 1.1 2.5 -0.6 -1.0 -1.6 -1.3 -1.4 -0.4 -0.6 -0.9
Vitamin and mineral supplements 0.1 0.2 0.6 -0.3 -0.6 0.8 -0.5 -0.2 -0.1 0.3 -0.0
Supplements: Zinc 0.1 0.1 0.9 -0.0 0.0 0.1 0.0 0.3 0.9 0.2 0.3
Medication: Co-codamol 0.4 0.4 1.1 -0.2 0.7 1.1 1.0 0.8 -0.1 -0.0 0.5
Medication: Metformin 2.0 2.9 6.5 -0.0 1.5 -0.3 1.8 2.4 1.2 2.5 2.0
Diabetes (father) 0.4 0.5 1.2 1.1 -0.2 0.5 0.4 0.8 -0.5 1.1 0.9
Diabetes (mother) 1.3 1.7 4.7 0.8 0.9 2.0 1.0 1.0 -0.2 2.2 1.3
Severe depression (siblings) 1.3 1.5 2.6 1.5 -1.6 1.0 -1.4 -1.5 -1.0 -0.1 -0.9
Pack years adult smoking proportion 0.2 0.3 0.8 -0.4 -0.1 -0.5 -0.6 -0.7 0.7 -0.1 -0.9
Impedance of leg (right) 1.1 5.3 9.7 1.8 -2.2 -2.6 -1.5 -2.2 -2.9 -3.1 -1.6
Leg fat-free mass (left) 0.6 3.4 7.4 -0.4 1.9 0.3 2.4 2.7 0.6 2.6 1.6
Trunk fat percentage 0.5 2.0 7.6 2.4 -1.2 -0.0 0.5 0.3 -2.7 -0.9 -0.5
Hand grip strength (right) 0.5 1.3 3.5 -1.5 1.4 -1.9 1.4 0.7 0.5 -0.6 -0.2
Townsend deprivation index at recruitment 0.0 0.0 0.1 0.4 0.2 0.2 0.0 0.1 0.0 0.2 -0.4
Current tobacco smoking 0.4 0.6 2.2 -1.0 -0.3 -1.5 -0.1 -0.8 0.7 -0.5 -0.4
Average weekly fortified wine intake 1.3 1.5 3.6 -1.6 -0.4 -0.7 -1.9 -1.3 1.0 -0.5 -1.4
Maternal smoking around birth 0.5 0.8 3.6 0.4 0.3 1.9 0.2 0.4 0.7 1.0 0.7
Fed-up feelings 0.4 0.6 1.6 0.7 -0.5 0.5 -1.3 -0.8 -0.4 -0.2 -1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.3 0.1 -0.5 0.2 -0.1 0.3 0.1 0.3 0.2
Relative age voice broke 0.8 1.2 5.3 2.3 -1.1 1.3 -0.9 -0.3 -0.8 0.3 0.1
Taking other prescription medications 0.7 1.1 3.7 0.4 0.4 1.9 0.6 1.0 0.4 1.6 0.8
Age when periods started (menarche) 0.2 0.6 1.5 0.7 -0.8 1.1 -0.3 -0.2 -1.2 -0.5 -0.6
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 1.3 0.5 -0.6 -0.4 -1.1 -0.2 -0.1 -0.6 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 5.0 -1.9 0.7 -2.2 -0.0 -0.3 0.6 -0.6 -0.4
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 1.2 -0.0 -0.1 -0.7 0.1 -0.3 -0.2 -1.1 -0.7
Qualifications: CSEs or equivalent 0.3 0.4 1.8 -0.8 -0.3 -1.4 0.5 0.1 0.1 0.0 0.7
Serious illness, injury or assault to yourself 0.7 0.8 3.0 0.3 -1.0 -1.7 -1.0 -0.3 -1.0 -0.4 -0.3
High blood pressure 0.5 1.3 4.8 2.2 -1.2 0.7 -0.4 -0.9 -1.5 -0.4 -0.5
Hayfever, allergic rhinitis or eczema 0.2 0.5 1.3 -0.3 -0.6 0.1 -1.1 -0.9 0.2 -0.8 -0.7
Multivitamins +/- minerals 0.5 0.6 2.2 0.3 0.5 -1.5 0.6 -0.3 -0.5 -1.2 -0.4
Stomach or abdominal pain in last month 1.0 1.3 3.3 0.6 -1.2 -0.1 -1.8 -1.3 -1.0 -0.9 -1.3
Supplements: Glucosamine 0.4 0.5 1.8 -0.4 0.6 0.3 0.7 0.3 1.0 1.3 0.1
Diverticular disease/diverticulitis (self-reported) 2.6 3.1 9.5 -0.6 1.3 1.1 1.8 2.3 0.7 1.7 3.1
Medication: Atenolol 0.7 0.9 3.5 1.9 -0.3 0.3 -0.2 -0.3 -1.7 -0.2 -0.5
Medication: Levothyroxine sodium 0.3 0.6 2.2 -0.7 0.3 1.5 0.2 -0.0 0.9 0.9 0.6
Sitting height 0.2 1.1 3.4 -0.1 1.4 0.2 1.4 1.2 0.3 1.8 0.5
Chronic bronchitis/emphysema (father) 0.3 0.3 1.3 -0.6 -0.1 -0.0 0.5 0.4 1.2 0.3 0.7
High blood pressure (mother) 0.6 0.8 4.8 0.1 0.5 -0.5 0.5 0.6 -0.2 0.7 2.2
Body mass index (BMI) 0.1 0.5 1.3 0.7 -0.0 0.4 1.1 0.7 -0.9 0.6 0.3
Impedance of leg (left) 1.1 5.6 10.9 1.8 -2.4 -2.1 -1.7 -2.5 -2.8 -3.3 -1.8
Leg predicted mass (left) 0.7 3.6 7.8 -0.5 2.0 0.3 2.5 2.8 0.6 2.7 1.7
Trunk fat mass 0.3 1.3 3.8 1.8 -0.2 0.2 1.5 1.2 -2.0 0.2 0.2
Waist circumference 0.3 1.2 3.5 0.6 0.9 1.1 1.9 1.5 -0.6 0.6 0.5
Number of incorrect matches in round 0.6 1.0 2.0 -0.3 1.2 -0.3 1.4 1.3 0.8 0.7 1.3
Past tobacco smoking 0.6 1.1 2.0 -1.0 -1.2 -1.4 -0.9 -1.0 0.6 -0.9 -1.2
Alcohol usually taken with meals 0.4 0.6 1.4 -0.7 0.9 1.1 -0.6 0.5 1.2 0.4 0.3
Nervous feelings 0.5 0.9 3.0 -1.1 1.0 0.0 0.1 -0.1 1.7 0.8 -1.1
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 1.6 1.0 -0.4 0.7 -1.3 -0.4 -0.7 0.1 -0.2
Hearing difficulty/problems with background noise 0.8 1.3 5.2 2.3 -0.7 1.7 0.7 -0.2 -0.7 0.9 0.3
Hair/balding pattern: Pattern 2 0.6 0.8 2.2 0.6 -0.9 -1.5 -0.6 -1.3 -0.3 0.9 -0.0
Had menopause 1.1 1.4 3.3 0.1 -1.5 -0.3 -1.5 -1.6 0.1 -0.8 -1.8
Had other major operations 0.5 0.7 1.5 0.7 0.8 0.3 0.8 1.2 -0.8 0.4 1.1
Forced vital capacity (FVC) 1.5 5.8 11.6 -1.2 2.6 -0.2 2.9 3.4 1.0 2.8 3.1
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 2.9 -1.7 0.1 -1.5 -0.3 -1.1 0.4 -0.8 -0.9
Ever unenthusiastic/disinterested for a whole week 2.4 2.9 5.6 1.0 -1.6 -2.0 -1.8 -1.4 -1.5 -2.4 -1.7
Qualifications: None of the above 0.2 0.4 0.9 0.6 -0.9 0.1 -0.5 -0.8 -0.9 -0.6 -0.2
Financial difficulties in last 2 years 0.3 0.4 0.9 0.6 -0.5 -0.1 -0.9 -0.8 -0.4 0.3 1.0
Mouth/teeth dental problems 0.1 0.2 0.5 0.6 0.5 0.7 0.4 0.2 0.2 0.3 0.6
Heart attack 0.7 0.9 2.9 -1.7 0.2 0.7 -0.6 -0.5 1.3 -0.6 -0.8
Allergy 0.2 0.5 0.9 0.9 -0.9 -0.7 -0.1 -0.7 -0.9 -0.3 -0.4
Pain all over the body in last month 1.2 1.3 4.2 0.1 -2.0 -0.0 -1.2 -1.8 -0.9 -0.6 -0.7
Diabetes (self-reported) 1.9 2.9 6.4 0.1 1.4 1.1 1.5 2.2 1.6 2.5 2.0
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 1.7 -0.6 -0.6 -1.1 -1.1 -1.3 0.1 -0.8 -1.0
Medication: Ramipril 1.5 1.9 5.3 0.8 -1.7 0.0 -1.2 -1.6 -1.0 -1.3 -2.3
Medication: Simvastatin 2.0 3.0 9.2 0.0 1.3 2.8 0.9 1.1 1.0 3.0 1.5
Fluid intelligence score 0.4 0.9 3.4 -0.4 0.7 1.9 0.9 0.5 0.6 -0.7 -1.0
Illnesses of siblings 2.2 3.2 10.5 -3.2 2.1 -2.7 1.1 0.9 1.1 -0.4 0.4
Neuroticism score 0.3 0.6 1.8 0.2 -0.1 0.7 -0.9 -0.9 0.8 1.3 -0.4
Weight 0.3 1.4 4.2 0.7 0.8 0.4 2.0 1.7 -0.7 1.4 0.8
Impedance of arm (right) 0.6 2.7 6.7 2.2 -1.8 -1.7 -1.2 -0.6 -2.6 -1.5 0.0
Arm fat percentage (right) 0.3 1.0 3.5 1.6 -0.4 -0.2 1.0 1.0 -1.9 0.1 0.4
Trunk fat-free mass 0.9 5.1 9.5 -1.6 2.7 -0.1 2.8 2.7 1.6 3.1 1.9
Hip circumference 0.4 1.7 3.9 0.8 0.9 1.1 1.9 2.0 -0.4 1.5 0.8
Time employed in main current job 0.4 0.5 1.4 -0.2 -0.3 -1.2 -0.0 -0.5 -0.5 -1.1 -0.7
Alcohol intake versus 10 years previously 1.0 1.5 4.3 -0.3 1.7 2.1 1.5 1.1 0.8 0.8 0.2
Father’s age at death 0.7 0.9 3.5 0.4 1.2 0.2 1.2 1.9 0.1 -0.2 0.6
Worrier / anxious feelings 0.4 0.7 1.6 0.9 -0.7 0.7 -1.2 -0.9 0.1 0.7 -1.0
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 1.7 1.1 -0.9 -1.3 -1.0 -0.4 -1.1 0.3 0.3
Falls in the last year 0.8 1.0 3.2 1.0 0.6 1.8 0.6 1.2 -0.2 1.2 0.5
Hair/balding pattern: Pattern 3 0.7 1.0 2.5 -1.6 -0.0 0.4 -1.1 -0.8 0.6 -1.2 -1.3
Number of live births 0.5 0.7 3.4 0.9 -0.5 1.9 0.2 -0.8 -0.4 -0.3 -0.6
Forced expiratory volume in 1-second (FEV1) 1.7 5.8 11.6 -1.1 2.7 -0.5 2.9 3.4 0.8 2.5 3.3
Pulse rate 0.3 0.4 0.9 0.8 0.6 0.5 1.0 0.6 -0.8 0.3 0.5
Happiness 0.2 0.3 0.9 -0.1 -0.1 -1.0 0.1 -0.0 0.6 0.8 -0.4
Noisy workplace 0.5 0.6 3.1 -0.3 0.3 0.5 0.5 0.4 0.2 1.0 1.8
Qualifications: A levels/AS levels or equivalent 0.1 0.2 0.7 0.2 0.4 -0.1 0.7 0.8 0.2 0.5 0.6
Serious illness, injury or assault of a close relative in last 2 years 1.1 1.2 2.7 1.2 -0.6 1.6 -1.1 -1.0 -1.7 0.6 0.3
Mouth/teeth dental problems: Dentures 0.6 1.1 3.6 0.6 -1.3 1.9 -0.9 -1.2 -0.6 0.1 -0.6
Asthma 0.3 0.7 2.4 -1.5 0.7 0.7 0.5 0.1 1.2 0.4 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 1.4 0.8 -0.6 1.2 -0.5 -0.1 0.7 1.1 0.9
Medication: Cholesterol lowering 1.1 1.8 5.1 0.2 0.7 1.8 0.7 1.5 1.3 2.3 1.0
Depression (self-reported) 0.4 0.5 1.4 0.4 -0.4 -0.6 0.1 0.3 -0.5 1.2 1.1
Medication: Lansoprazole 0.3 0.3 1.0 -0.3 -0.1 -0.0 1.0 -0.3 -0.8 0.3 0.7
Prospective memory result 0.2 0.3 1.5 0.1 -0.3 -1.2 0.1 0.3 -0.3 -0.4 0.5
Lung cancer (father) 0.9 1.1 3.3 0.9 -1.0 -0.4 -1.2 -1.8 -0.3 -0.8 -1.1
Illnesses of mother 1.1 1.4 4.9 -1.3 0.7 -1.4 0.4 -0.0 0.2 -1.5 -2.2
Forced expiratory volume in 1-second (FEV1), Best measure 1.5 4.7 10.9 -0.0 2.4 -0.7 2.9 3.3 0.0 2.4 2.5
Pulse wave Arterial Stiffness index 0.8 0.9 2.2 1.3 -0.3 -0.4 -0.3 -0.6 -0.9 -1.3 -1.5
Impedance of arm (left) 0.4 2.1 4.9 2.2 -1.4 -0.7 -1.1 -0.4 -2.2 -1.6 -0.5
Arm fat mass (right) 0.3 1.3 3.4 1.1 0.4 0.2 1.9 1.5 -1.4 0.9 0.8
Trunk predicted mass 1.0 5.5 9.9 -1.6 2.8 -0.1 2.9 2.8 1.6 3.2 2.1
Standing height 0.2 1.8 4.2 0.1 1.6 -0.6 2.0 2.0 -0.1 1.5 1.0
Length of working week for main job 1.9 2.1 5.5 0.6 1.7 1.1 1.4 1.7 0.4 2.4 1.0
Exposure to tobacco smoke at home 1.5 1.7 2.6 1.2 -1.5 -1.5 -1.3 -1.2 -1.6 -1.5 -0.3
Breastfed as a baby 0.2 0.2 0.8 -0.3 0.1 -0.9 0.1 0.5 0.6 -0.1 -0.5
Tense / ‘highly strung’ 0.4 0.7 1.8 -0.5 1.4 0.0 0.8 1.1 0.7 1.0 0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.1 0.3 0.1 0.2 0.4 -0.2 -0.2 -0.5 0.3 -0.4
Hair/balding pattern: Pattern 4 0.2 0.4 0.9 0.5 -0.8 0.8 -1.0 -0.5 -0.0 0.2 0.6
Birth weight of first child 0.3 0.6 1.8 0.9 -0.3 -0.8 0.2 -0.1 -1.4 -0.2 -0.9
Peak expiratory flow (PEF) 1.0 2.3 6.3 -0.4 1.1 -1.2 1.8 2.5 0.3 1.5 2.0
Pulse wave reflection index 0.6 0.7 1.8 0.9 -0.7 -0.4 -0.4 -1.0 -0.3 -1.3 -1.1
Ever highly irritable/argumentative for 2 days 1.3 1.6 5.2 -0.3 -0.6 -2.1 -0.5 -0.7 -0.1 -2.3 -1.4
Loud music exposure frequency 0.7 0.8 2.5 -0.2 -1.0 -1.6 -0.8 -0.9 -0.7 -1.0 -0.1
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.4 -0.0 0.2 -1.2 0.6 0.5 -0.6 0.7 1.2
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 2.5 -0.5 -0.9 -1.1 -0.4 -0.5 -0.7 -1.6 -1.1
Blood clot in the leg (DVT) 0.9 1.2 2.2 1.1 0.8 0.7 0.9 1.4 -0.8 1.3 1.5
Medication: Paracetamol 0.6 1.1 3.3 -0.1 0.8 0.3 0.7 1.1 0.9 1.4 1.8
Headache pain in last month 0.9 1.6 4.2 2.0 0.1 0.9 -0.5 1.3 -1.1 1.8 1.1
Medication for cholesterol, blood pressure or diabetes 0.6 1.0 2.6 -0.7 -0.6 -1.6 -0.2 -0.9 -1.2 -1.6 -0.2
Glaucoma (self-reported) 3.4 4.0 8.9 -0.1 2.0 2.6 2.0 1.7 -0.3 2.4 3.0
Gout (self-reported) 1.0 1.3 3.5 -0.8 -1.3 -1.9 -1.1 -1.5 0.0 -1.1 -0.6
Hypothyroidism/myxoedema (self-reported) 0.4 0.9 3.0 -1.1 0.0 1.7 -0.0 -0.3 1.4 0.8 0.3
Medication: Amlodipine 1.7 2.3 3.4 -1.8 1.6 1.5 1.4 1.4 1.8 1.4 1.1
Medication: Ventolin 100micrograms inhaler 0.4 0.6 1.0 -1.0 0.8 0.3 0.6 0.1 0.8 1.0 0.9
Birth weight 2.2 4.9 7.8 -1.1 2.5 1.7 2.8 2.8 2.2 1.9 2.1
Chronic bronchitis/emphysema (mother) 1.7 2.0 5.7 0.8 -1.7 -1.0 -2.4 -1.5 -0.8 -0.6 -1.7
High blood pressure (siblings) 0.6 0.8 1.6 1.3 -1.3 1.3 -0.9 -0.6 -0.3 -0.6 -0.4
Forced vital capacity (FVC), Best measure 1.2 4.4 10.2 0.0 2.4 -0.4 2.5 3.2 0.3 2.7 2.4
Body fat percentage 0.5 1.9 6.8 2.3 -1.2 -0.0 0.5 0.2 -2.6 -1.1 -0.7
Leg fat percentage (right) 0.3 1.2 4.5 1.7 -0.5 -0.3 1.2 0.4 -2.1 -0.4 -0.1
Arm fat-free mass (right) 0.6 3.1 7.6 -1.0 2.3 0.3 2.8 2.4 1.1 1.8 0.9
Exposure to tobacco smoke outside home 0.3 0.3 1.8 0.2 -0.2 -1.3 -0.0 -0.7 -0.3 -0.4 -0.3
Comparative body size at age 10 0.2 0.5 2.3 -1.0 0.1 -0.3 0.3 0.3 0.3 0.7 1.5
Number of full brothers 0.7 0.9 2.2 1.5 -0.7 0.9 -0.2 0.2 -1.3 0.2 1.4
Worry too long after embarrassment 0.5 0.9 2.3 0.8 -0.7 0.8 -1.5 -0.7 -0.2 1.5 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 2.2 2.9 5.4 -1.5 2.3 0.7 1.8 2.0 1.8 1.4 1.7
Wheeze or whistling in the chest in last year 0.4 0.8 2.3 0.7 -1.5 0.9 -0.7 -0.9 -0.9 -0.7 -0.3
Number of children fathered 0.2 0.2 0.7 -0.8 -0.3 -0.2 -0.2 -0.3 0.1 0.1 0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 2.5 1.5 -1.0 1.2 -0.4 -0.4 -0.5 -0.7 -1.6
Age at first live birth 0.7 1.3 2.6 -1.1 -0.8 -0.7 -1.5 -1.3 -0.2 -1.3 -1.6
Pulse wave peak to peak time 0.8 1.0 2.3 -1.1 0.4 0.5 0.5 0.8 0.8 1.5 1.5
Health satisfaction 0.7 0.9 2.3 0.5 -0.8 0.3 -1.5 -0.7 0.3 -1.3 -1.5
Shortness of breath walking on level ground 0.2 0.2 1.1 0.3 -0.7 0.1 0.2 0.0 -1.1 -0.5 0.3
Qualifications: College or University degree 0.7 2.1 5.6 0.7 0.8 2.4 0.7 1.6 1.4 2.1 0.7
Eye problems/disorders: None of the above 1.8 2.1 4.5 0.7 -1.6 -2.1 -2.1 -1.6 -0.7 -0.9 -1.1
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.2 0.7 -0.9 -0.7 -0.5 -0.6 -0.6 -0.8 -1.1
Emphysema/chronic bronchitis 0.3 0.4 0.8 -0.4 -0.6 0.7 -0.6 -0.9 0.3 0.7 -0.5
Medication for pain relief, constipation, heartburn 0.2 0.3 1.1 -0.4 -0.1 -1.0 -0.2 -0.0 -0.8 -0.4 0.2
Neck or shoulder pain in last month 1.0 1.4 3.4 1.8 -0.9 0.2 -1.4 -1.0 -1.1 -0.6 -1.5
Medication: Blood pressure 0.1 0.2 0.6 0.4 0.3 0.3 -0.1 0.3 0.8 0.7 -0.1
Angina (self-reported) 0.1 0.2 0.8 0.5 -0.0 0.3 -0.0 0.3 -0.9 0.0 0.1
Migraine (self-reported) 0.5 0.6 2.3 -0.0 1.1 0.5 0.4 0.6 0.4 1.5 0.8
Medication: Ibuprofen 0.4 0.5 1.3 0.5 -0.0 0.9 -0.1 0.4 0.7 1.1 1.1
Medication: Allopurinol 1.4 1.8 4.4 -0.1 -1.5 -1.2 -1.9 -2.1 -0.4 -1.2 -1.2
Medication: Omeprazole 0.4 0.5 1.1 -0.7 -0.2 -0.1 -0.9 -0.8 1.0 0.6 -0.5
Medication: Seretide 50 evohaler 0.2 0.2 1.0 -1.0 0.6 0.3 0.3 -0.1 0.2 -0.2 0.1
Mean time to correctly identify matches 0.2 0.4 0.7 0.3 0.7 0.7 0.3 0.7 0.4 0.8 -0.7
Heart disease (mother) 0.4 0.5 1.4 1.0 -0.1 -0.2 -0.1 0.4 -1.2 -0.2 1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 7.0 -2.6 0.7 -0.8 0.3 -0.3 0.9 -0.0 0.0
Whole body fat mass 0.3 1.2 3.3 1.7 -0.2 0.3 1.4 1.0 -1.8 0.1 0.0
Leg fat mass (right) 0.3 1.2 4.0 1.7 -0.3 -0.1 1.4 0.8 -2.0 0.2 0.2
Arm predicted mass (right) 0.5 2.7 6.3 -1.0 2.1 0.6 2.5 2.0 1.1 1.9 0.7
Pulse rate, automated reading 0.2 0.5 1.5 -0.8 -0.0 -0.3 -0.7 -1.2 0.5 -0.5 -0.9
Alcohol intake frequency. 0.7 1.6 5.3 -1.9 0.2 -2.3 -0.5 -0.5 1.4 0.4 0.8
Comparative height size at age 10 0.4 2.3 6.9 -0.3 2.0 0.3 2.5 2.6 0.7 0.4 0.5
Number of full sisters 2.3 2.8 5.3 2.2 -2.3 0.7 -2.3 -1.5 -1.6 0.2 1.2
Suffer from ‘nerves’ 0.6 0.9 4.2 -0.4 -0.7 -2.0 -1.1 -0.8 -0.1 0.8 -0.2
Overall health rating 0.5 1.1 6.0 1.5 0.3 2.4 0.4 0.5 -0.6 0.2 -0.4
Chest pain or discomfort 0.5 0.8 1.7 0.9 -1.0 -0.1 -0.6 -0.9 -1.3 -1.1 -0.4
Had major operations 1.4 1.6 6.6 -0.3 1.3 2.6 0.3 1.2 1.3 1.0 0.5
Age at last live birth 0.4 0.5 2.2 -0.9 0.2 0.7 0.1 -0.4 -0.5 -0.6 -1.5
Family relationship satisfaction 0.5 0.6 1.8 1.3 -0.9 -0.8 -0.4 -0.6 -1.0 0.5 0.4
Leg pain on walking 0.2 0.3 0.7 -0.5 0.5 -0.8 0.7 0.1 0.4 -0.8 -0.1
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.7 -0.6 -0.2 -0.8 -0.4 -0.9 -0.0 0.7 0.5
Commuting to job workplace: Car/motor vehicle 0.1 0.2 0.4 0.4 0.3 0.5 0.6 0.2 -0.4 0.3 -0.4
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.6 -0.5 -0.0 0.9 0.5 -0.1 1.3 -0.8 -1.3
Medication: Aspirin 0.7 0.9 1.6 -0.9 1.3 0.3 1.2 0.8 1.0 -0.2 -1.2
Supplements: Vitamin C 0.6 0.7 3.0 -0.2 -0.0 -0.2 -1.0 -0.8 1.7 0.3 -1.1
Knee pain experienced in last month 0.5 0.7 1.2 1.1 -1.1 1.0 0.8 0.3 -0.6 0.8 0.7
Hypertension (Self-reported) 0.6 1.7 5.7 2.4 -1.5 0.5 -0.6 -1.1 -1.8 -0.5 -0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.0 2.3 7.9 2.0 -1.9 2.8 -0.8 -1.0 -0.8 0.9 0.3
Illnesses of father: Heart disease 1.5 2.1 6.8 2.6 -1.1 2.0 -0.8 -0.2 -1.9 0.2 0.7
Illnesses of siblings: Diabetes 1.3 1.6 5.4 1.0 0.7 2.3 1.6 1.3 0.6 0.8 0.9
Smoking status: Previous 0.4 0.6 1.3 0.8 0.5 1.1 0.1 0.6 -1.0 0.5 1.0
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 4.2 1.4 -0.0 -2.0 0.2 0.7 -1.4 1.1 0.8
Whole body fat-free mass 0.8 4.4 8.3 -1.1 2.5 0.2 2.8 2.8 1.3 2.9 1.8
Leg fat-free mass (right) 0.7 3.9 8.3 -0.6 2.0 0.9 2.5 2.7 1.0 2.9 1.7
Arm fat percentage (left) 0.2 0.9 2.3 1.5 -0.2 0.2 1.0 1.1 -1.5 0.1 0.1
Average weekly red wine intake 0.9 1.4 2.8 1.0 -0.9 1.7 -1.6 -1.2 -1.0 -0.3 -1.2
Handedness (chirality/laterality): Left-handed 0.2 0.3 1.6 -0.5 -0.3 -1.3 -0.2 -0.2 0.0 -0.2 -0.3
Mood swings 0.1 0.2 0.9 0.2 -0.1 0.9 0.3 -0.3 -0.0 0.9 0.3
Loneliness, isolation 0.6 0.8 2.8 -0.5 1.1 -0.3 0.8 0.5 0.8 1.7 0.9
Long-standing illness, disability or infirmity 0.4 0.7 2.5 0.5 0.5 1.6 0.6 1.0 0.3 0.9 0.1
Ever had bowel cancer screening 1.8 2.1 9.3 2.1 -0.6 3.0 0.2 0.1 -0.3 1.5 0.8
Diabetes diagnosed by doctor 1.6 2.5 5.1 0.5 1.4 0.8 1.9 2.2 1.4 2.0 1.6
Ever had stillbirth, spontaneous miscarriage or termination 2.6 2.8 6.3 -1.2 1.8 -0.5 1.9 1.5 1.2 2.5 1.9
Friendships satisfaction 0.3 0.3 0.9 -0.7 0.1 -0.6 -0.5 -0.7 0.5 0.1 -1.0
Qualifications: nursing, teaching 0.4 0.6 3.5 -0.3 -0.3 -1.9 -0.8 0.0 -0.3 0.3 0.5
Commuting to job workplace: Walk 1.1 1.2 3.6 0.9 -1.9 -1.1 -1.4 -0.7 -0.6 1.0 0.1
Eye problems/disorders: Cataract 0.6 0.7 1.8 -0.6 0.7 1.2 1.3 0.6 0.6 -0.4 0.7
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 1.3 -0.0 0.1 0.1 -0.2 0.1 0.4 1.1 1.1
Medication for cholesterol 0.1 0.2 0.5 -0.1 -0.4 -0.0 -0.3 0.1 0.6 -0.2 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.4 1.2 0.6 0.8 0.4 1.1 0.7 -0.2 -0.0 0.6
Back pain experienced in last month 0.1 0.2 0.8 0.2 -0.3 0.4 -0.6 -0.3 0.1 -0.3 -0.9
Mineral and other dietary supplements 0.4 0.5 0.9 0.8 0.2 0.2 0.9 0.9 -0.9 -0.6 0.7
Breast cancer (self-reported) 0.7 0.9 4.8 -0.1 0.7 -2.2 0.5 0.9 0.1 0.6 0.6
Asthma (self-reported) 0.3 0.5 1.9 -1.4 0.7 0.5 0.5 0.1 0.9 0.4 0.5
Osteoporosis (self-reported) 0.6 0.7 2.3 -1.5 0.1 -0.0 -0.4 -0.3 1.2 -0.9 -0.8
Osteoarthritis (self-reported) 1.0 1.2 2.9 1.2 -1.4 1.7 -0.6 -1.3 -0.8 1.1 0.0
Medication: Aspirin 0.6 0.8 1.8 -0.9 1.0 0.4 0.8 0.4 1.4 0.1 -1.3
Medication: Gliclazide 0.4 0.5 2.2 0.5 0.1 -0.1 0.1 0.7 0.7 1.5 0.6
Illnesses of father: None of the above (group 1) 0.5 0.6 2.4 -0.7 0.5 -1.6 0.1 -0.3 0.5 -0.8 -0.9
Smoking status: Current 0.3 0.5 1.9 -0.9 -0.0 -1.4 0.3 -0.3 0.8 -0.3 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.1 1.9 -0.8 1.4 -0.2 1.1 1.4 0.8 1.1 1.0
Whole body water mass 0.9 5.0 9.4 -1.2 2.6 0.3 2.9 2.9 1.4 3.1 1.9
Leg predicted mass (right) 0.7 3.7 8.1 -0.5 1.9 1.0 2.4 2.6 1.0 2.8 1.7
Arm fat mass (left) 0.3 1.2 3.4 1.0 0.5 0.3 1.8 1.6 -1.2 0.8 0.8
Number of self-reported non-cancer illnesses 0.6 1.1 3.3 0.9 0.1 1.5 0.4 1.1 0.3 1.8 0.9
Average weekly champagne plus white wine intake 0.6 0.9 2.3 1.0 0.7 -0.1 0.7 1.3 -0.4 1.0 1.5
Miserableness 1.4 2.5 6.7 1.0 -2.0 0.1 -2.6 -2.3 -1.5 -0.2 -0.8
Guilty feelings 0.8 1.2 2.9 1.7 -1.1 0.2 -1.3 -1.5 -0.8 0.7 -0.6
Wears glasses or contact lenses 1.4 1.7 6.2 1.3 -0.7 2.5 -1.5 -1.0 -0.1 -0.1 -1.3
Ever taken oral contraceptive pill 0.3 0.4 1.1 0.4 -1.1 -0.5 -0.8 -0.5 0.6 -0.2 0.3
Hearing aid user 0.1 0.1 0.6 -0.4 0.8 0.3 0.2 -0.1 0.3 -0.3 -0.1
Mother’s age at death 2.0 2.6 7.7 -2.8 1.6 0.3 0.6 1.4 2.8 0.1 0.4
Financial situation satisfaction 2.2 2.7 4.5 2.0 -1.6 -0.6 -2.1 -1.8 -2.1 -1.0 -1.3
Tinnitus: Yes, now most or all of the time 1.3 1.5 2.6 -1.0 1.3 1.5 1.2 1.5 1.6 0.2 1.0
Commuting to job workplace: Public transport 0.2 0.2 0.7 -0.3 0.2 -0.4 -0.3 -0.2 0.8 0.5 0.2
Eye problems/disorders: Glaucoma 1.2 1.5 3.6 -0.2 1.4 1.9 1.5 1.3 -0.3 0.6 1.3
Medication: Blood pressure 0.4 0.7 2.3 1.1 0.3 1.5 0.9 0.1 -0.8 -0.4 -0.4
Pain type(s) experienced in last month: Hip pain 1.9 2.4 4.8 0.4 -1.9 -1.3 -1.8 -2.2 -0.2 -1.5 -1.9
Supplements: Fish oil (including cod liver oil) 0.1 0.2 0.5 -0.7 0.4 -0.1 -0.2 -0.3 0.5 -0.2 -0.5
High cholesterol (Self-reported) 0.5 0.9 3.4 1.1 -0.4 1.9 0.1 0.1 0.1 1.5 0.1
Medication: Bendroflumethiazide 0.2 0.3 1.3 0.4 -0.1 1.1 0.7 -0.5 0.4 -0.5 -0.1
Medication: Paracetamol 1.5 2.3 4.1 -1.4 1.6 -0.3 1.4 1.6 1.8 1.4 2.0
Medication: Lisinopril 0.6 0.7 2.7 0.6 0.6 1.6 1.0 0.9 -0.5 -0.7 -0.1
Medication: Atorvastatin 0.6 0.7 1.7 0.1 1.1 1.1 1.0 1.3 0.7 -0.1 -0.3
Illnesses of father: High blood pressure 0.6 0.7 2.0 1.4 -1.1 0.7 -0.4 -0.3 -1.2 0.3 0.4
Alcohol drinker status: Never 1.7 2.0 6.9 -2.6 1.8 -1.1 -0.0 0.7 1.9 0.6 0.4
Ever smoked 0.6 1.0 3.1 -0.1 1.8 0.3 1.2 0.9 0.2 0.9 1.4
Basal metabolic rate 0.7 3.7 7.3 -0.8 2.1 0.2 2.7 2.6 0.8 2.6 1.6
Leg fat percentage (left) 0.3 1.0 3.7 1.6 -0.6 0.2 1.0 0.2 -1.9 -0.5 -0.2
Arm fat-free mass (left) 0.5 2.6 6.0 -1.1 2.0 -0.1 2.4 2.0 0.7 1.9 1.1
Number of operations (self-reported) 0.9 1.4 3.5 -0.9 1.9 1.3 1.3 1.2 0.8 0.6 1.1
Average weekly beer plus cider intake 0.4 0.6 1.8 0.7 0.5 -0.4 1.0 -0.1 -1.4 0.7 0.6
Irritability 0.1 0.2 1.0 -0.2 0.4 0.2 1.0 0.1 0.4 -0.1 0.3
Risk taking 1.8 2.6 5.6 -0.0 1.9 1.5 1.4 1.9 0.6 1.7 2.4
Ever had prostate specific antigen (PSA) test 1.2 1.4 5.3 0.6 0.7 2.0 0.3 0.6 -0.0 2.3 0.8
Fractured/broken bones in last 5 years 0.9 1.2 2.1 0.7 -1.3 -1.0 -1.4 -1.1 -0.4 -1.0 -1.5
Age started oral contraceptive pill 0.2 0.2 0.9 0.7 0.1 -0.2 0.1 0.2 -0.3 -1.0 -0.3
Diastolic blood pressure, automated reading 1.0 3.2 5.6 2.1 -2.0 -1.1 -1.5 -1.8 -2.4 -1.9 -0.8
Ever depressed for a whole week 0.5 0.7 1.7 -0.5 1.3 -0.7 0.2 0.8 0.6 1.0 0.8
Unable to work because of sickness or disability 0.4 0.5 1.0 -1.0 0.7 0.9 -0.1 0.5 1.0 0.6 0.0
Commuting to job workplace: Cycle 0.4 0.5 0.9 0.8 -0.1 -0.4 -0.6 -0.2 -0.8 1.0 1.0
Myopia 0.9 1.2 3.7 0.8 -0.6 1.9 -1.0 -0.6 0.1 1.9 0.5
Vascular/heart problems diagnosed by doctor 0.3 0.8 3.3 -1.8 0.7 -0.9 0.4 0.6 0.9 -0.1 0.2
Cholesterol lowering medication 0.6 0.9 2.9 -0.3 1.0 1.7 0.9 0.6 0.3 1.4 0.3
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.7 -0.2 -0.7 -0.9 -1.3 -1.1 0.0 0.4 -0.5
Pain experienced in last month 1.9 3.1 7.9 -2.8 2.1 -0.6 1.6 1.3 2.4 1.0 1.2
Supplements: Calcium 0.6 0.6 1.9 -0.0 -0.3 0.7 -1.0 -0.7 0.7 -0.6 -1.4
Basal cell carcinoma (self-reported) 0.4 0.5 2.7 0.6 0.3 1.7 -0.2 0.3 -0.2 0.1 -0.5
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.8 -1.7 0.2 0.8 -0.4 -0.4 1.3 -0.5 -0.8
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 2.3 1.1 0.8 1.2 1.0 1.4 -0.7 1.5 1.5
Heart disease (siblings) 3.3 4.0 12.7 3.3 -1.8 3.6 -1.3 -1.0 -1.3 0.7 -0.6
Alcohol drinker status: Previous 0.8 0.9 3.5 0.3 -1.2 -0.3 -1.1 -1.9 -0.7 -0.7 -0.2
Pack years of smoking 0.3 0.5 1.5 -0.3 -0.2 -0.1 -0.7 -0.8 1.0 -0.3 -1.2
Impedance of whole body 1.1 5.8 10.5 2.4 -2.5 -1.7 -1.9 -2.0 -3.2 -3.2 -1.6
Leg fat mass (left) 0.3 1.0 3.4 1.5 -0.3 0.1 1.4 0.7 -1.8 0.1 0.1
Arm predicted mass (left) 0.5 2.4 5.9 -0.9 1.9 0.2 2.4 1.9 0.8 1.9 1.0