Hub : Genes

ST6GALNAC3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0730 0.0300 7.8e-03 0.006 0.027 0.009 0.026 0.003 5.1e-02 2.6e-04 2.7e-02 3.1e-04 1.3e-01
2 GTEx Thyroid 0.2100 0.0470 3.6e-06 0.102 NA 0.137 NA 0.123 3.3e-08 NA 1.2e-10 NA 1.2e-09
3 NTR Blood 0.0243 0.0088 1.4e-03 0.019 0.009 0.019 0.015 0.022 4.8e-07 6.0e-04 5.8e-07 6.6e-06 1.1e-07
4 ROSMAP Brain Pre-frontal Cortex 0.0857 0.0297 1.4e-03 0.021 0.028 0.033 0.037 0.034 8.9e-04 1.5e-04 4.3e-05 1.2e-05 2.8e-05
5 YFS Blood 0.0824 0.0174 2.2e-12 0.017 0.049 0.044 0.050 0.044 1.4e-06 9.2e-16 2.4e-14 6.7e-16 3.7e-14
6 TCGA Colon Adenocarcinoma 0.1730 0.0710 8.1e-03 0.158 0.015 0.118 NA 0.132 2.0e-09 4.4e-02 2.6e-07 NA 4.9e-08
7 TCGA Brain Lower Grade Glioma 0.0777 0.0366 3.7e-03 -0.001 0.016 0.008 NA 0.001 4.1e-01 5.0e-03 3.6e-02 NA 2.2e-01
8 TCGA Testicular Germ Cell Tumors 0.4650 0.1240 7.3e-04 0.018 0.083 0.037 NA -0.006 7.5e-02 7.3e-04 1.8e-02 NA 6.0e-01
9 TCGA Thyroid Carcinoma 0.2010 0.0420 4.2e-11 0.180 0.117 0.176 NA 0.176 2.9e-17 1.9e-11 6.8e-17 NA 7.8e-17

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.5 0.8 2.7 -0.9 1.1 1.6 0.0 0.4 -0.1 0.5 0.5 1.5
Bipolar Disorder or Schizophrenia 0.4 1.0 5.4 -2.3 -0.9 -0.4 -0.0 -1.3 0.6 0.0 0.7 -0.4
Depressed Affect (Nagel 2018) 1.4 2.9 5.5 2.2 1.6 -0.1 1.6 -1.3 2.2 2.3 -1.5 1.0
Depression (Nagel 2018) 1.4 2.0 4.6 1.8 1.8 -0.2 2.1 -0.5 1.5 1.5 -1.2 1.1
Intelligence (Savage-Jansen 2018) 1.6 4.9 21.3 1.4 -1.3 -0.3 -4.6 2.2 -1.2 2.9 1.3 -1.6
Neuroticism (Nagel 2018) 1.4 3.2 10.6 1.4 0.7 -0.9 1.7 -1.7 2.9 3.3 -0.7 0.1
Schizophrenia (2018) 1.1 2.3 4.9 -2.2 -2.1 -1.8 -0.0 -2.0 0.8 -0.4 0.4 -1.7
Schizophrenia vs Biploar Disorder 2.1 2.8 7.3 -0.1 -1.9 -2.7 -0.5 -1.8 1.5 1.0 -0.7 -2.6
Worry (Nagel 2018) 1.2 2.5 10.2 1.4 0.8 -0.8 0.8 -0.9 2.7 3.2 0.3 0.2
Alzheimer’s Disease (in mother) 1.0 1.1 3.9 0.8 1.1 0.4 2.0 -0.8 -1.1 0.2 -1.2 0.9
Alzheimer’s Disease (in father) 1.5 1.7 9.1 -1.6 -0.7 -1.0 -0.8 -3.0 0.6 -0.7 0.4 -0.5
Alzheimer’s Disease (including proxy) 0.7 1.0 6.8 -0.1 0.4 -0.6 1.1 -2.6 -0.2 -0.2 -0.5 0.3
Crohns Disease (2017) 0.1 0.2 0.4 -0.0 -0.6 0.2 0.7 -0.1 0.0 0.5 -0.5 -0.1
Irritable Bowel Disease (IBD) 0.1 0.3 1.3 0.3 -0.5 -0.3 0.6 -1.1 0.2 -0.6 -0.0 -0.2
Ulcerative Colitis (UC) 0.3 0.5 2.0 0.5 -0.3 -0.7 0.4 -1.4 0.3 -1.1 0.6 -0.3
Major Depression (MDD) 0.4 0.5 2.5 -0.1 0.4 -0.0 1.6 -0.6 0.9 -0.0 -0.9 0.2
Reaction Time 0.6 1.2 4.7 -0.6 -0.0 0.7 2.2 0.7 -0.6 -1.0 -1.8 0.1
Verbal and Numeric Reasoning (VNR) 1.3 3.2 18.3 -0.6 -1.6 -0.3 -4.3 1.6 -1.0 0.7 0.6 -1.6
Breast Cancer 0.1 0.3 1.3 -0.0 1.1 0.2 0.1 -0.6 0.5 0.5 -0.4 0.5
Ovarian Cancer 0.4 0.5 1.2 0.2 -0.7 -1.1 0.5 -0.7 0.1 -0.5 0.9 -0.9
Prostate Cancer 1.5 2.2 7.5 0.9 1.0 -0.7 -1.6 1.3 2.7 2.1 1.1 -0.1
Age at First Birth 0.9 1.3 3.0 -0.4 -1.1 -1.7 -1.0 -1.4 1.3 0.6 0.8 -1.1
Bipolar Disorder (2011) 0.9 0.9 2.2 0.5 0.7 0.8 1.5 0.9 0.8 1.4 -0.7 0.8
Body Mass Index (BMI) (2010) 0.4 0.5 2.4 0.7 0.1 -0.3 0.3 -1.6 0.2 1.0 -0.1 0.3
Coronary Artery Disease (CAD) 0.2 0.3 0.7 -0.3 -0.5 0.2 0.3 0.5 -0.9 -0.8 0.4 -0.3
Crohns Disease (2012) 0.2 0.3 0.9 -0.3 -0.9 0.0 -0.5 -0.6 -0.5 0.9 0.2 -0.3
Mean Putamen Volume 0.5 0.6 3.6 0.5 -0.2 -0.6 1.9 -0.0 -0.2 -0.3 -0.5 -0.6
Fasting Glucose 1.4 1.7 6.9 -0.4 -0.8 -1.2 1.5 -2.6 -1.5 -0.9 0.3 -0.7
HbA1C 0.3 0.4 1.1 -0.4 -0.3 0.2 1.0 -0.7 0.1 -1.0 -0.6 -0.2
HDL Cholesterol 0.9 1.5 3.2 -1.0 -1.8 -1.2 -1.6 -0.1 -0.8 0.3 1.1 -1.7
LDL Cholesterol 0.4 0.7 1.5 1.0 0.3 -0.6 -0.6 0.9 0.8 1.1 -1.2 -0.3
Lupus 0.2 0.3 0.9 0.5 0.5 0.9 0.3 -0.2 0.1 -0.1 0.2 0.9
Neuroticism (2016) 1.6 2.3 12.3 0.9 -0.2 -1.0 1.2 -0.3 2.1 0.0 -3.5 -0.8
Primary Biliary Cirrhosis 1.2 1.8 7.5 -1.4 -1.9 -1.0 -0.4 -2.7 -0.7 -0.0 0.7 -0.7
Rheumatoid Arthritis 0.8 1.1 3.5 1.9 0.8 0.6 0.8 0.2 0.7 1.2 -1.1 1.1
Schizophrenia (2014) 1.3 3.0 6.8 -2.6 -2.3 -2.2 0.4 -2.1 1.0 -0.5 0.2 -2.0
Triglycerides 0.3 0.6 1.7 -0.5 -0.3 -0.5 1.1 -0.7 1.3 -0.5 -0.6 -0.7
Type 2 Diabetes (T2D) (2012) 0.3 0.4 1.5 0.1 -1.2 0.3 -0.5 0.6 0.4 -0.8 0.0 -0.4
Ulcerative Colitis 1.0 1.5 8.4 -1.3 -0.8 -1.2 0.7 -2.9 -0.3 -0.6 0.4 -0.4
Blood Eosinophil Count 0.3 2.5 6.4 0.9 2.5 2.0 0.3 1.5 0.1 -1.0 -1.6 2.2
Blood Platelet Count 0.1 0.8 2.7 -0.9 0.0 0.0 1.0 -1.6 -1.2 -1.0 -0.6 0.2
Blood Red Count 0.0 0.3 1.4 0.5 -0.3 -0.1 -0.0 0.0 1.2 0.6 -0.4 0.0
Blood White Count 1.4 10.1 19.6 3.5 4.4 4.2 1.3 3.6 -0.1 -0.8 -2.9 4.2
Heel T-Score 0.2 1.7 5.4 0.5 -0.4 -0.3 -1.9 1.6 1.7 2.3 0.5 -0.6
BMI 0.2 1.0 3.6 0.4 1.4 0.4 -1.0 -1.9 -1.1 -0.0 -0.2 1.0
Height 0.6 12.1 33.9 4.0 4.6 3.8 -1.0 2.5 -3.0 2.7 -0.2 5.8
Waist Hip Ratio (WHR) 0.1 0.6 1.3 0.4 0.8 1.1 0.4 0.8 -1.0 -0.2 -0.5 1.0
Systolic Blood Pressure 0.3 1.7 3.5 1.0 -1.5 -1.3 0.8 -1.7 0.5 1.9 0.6 -1.5
Smoking Status 1.2 2.9 7.9 2.4 2.0 -0.2 1.6 0.4 2.8 2.1 0.2 1.1
Allergy or Eczema 0.2 0.4 1.3 0.4 -0.4 -1.1 -0.4 -1.1 -0.1 0.6 -0.1 -0.7
Cardiovascular Disease 0.3 0.9 2.2 1.2 1.5 0.4 0.6 -0.6 0.6 1.5 -0.6 0.7
Hypothyroidism (self reported) 0.2 0.5 1.6 -0.8 -1.0 0.2 0.0 -0.0 0.2 -1.3 1.3 0.0
Respiratory disease 0.7 1.6 5.9 2.4 1.2 0.5 1.1 1.6 0.5 0.3 -1.3 1.0
Type 2 Diabetes (T2D) (2018) 0.4 0.7 3.0 0.6 -0.1 0.0 0.5 0.3 -0.3 1.7 -1.4 -0.3
Lung FEV1/FVC ratio 0.4 1.8 4.9 -0.7 -2.2 -1.3 -1.7 -1.1 -1.0 -0.3 -1.4 -1.5
Lung FVC 0.3 1.7 4.8 0.6 0.7 -0.2 -2.0 0.9 2.0 2.2 1.0 -0.0
Neuroticism 1.7 4.0 11.6 1.9 1.0 -0.6 1.6 -2.1 3.3 3.4 -1.0 0.5
Chronotype (morning person) 0.4 0.9 2.8 0.5 -1.6 -1.1 -0.4 0.2 -0.6 0.8 -0.1 -1.7
Hair Pigment 0.0 1.0 4.4 -0.5 -0.8 -0.1 2.1 -0.7 0.1 -0.2 -1.6 -0.7
Tanning 0.0 0.5 1.5 -0.1 0.9 0.6 0.4 1.2 1.2 -0.1 0.1 0.5
Hand grip strength (left) 0.4 1.0 2.5 1.1 1.6 0.6 1.0 -0.2 1.1 0.9 -0.3 1.2
Number of treatments/medications taken 1.2 2.2 4.8 1.7 2.2 1.8 0.0 1.6 0.6 0.9 -0.7 2.1
Average weekly spirits intake 0.9 1.2 4.5 -1.7 -0.1 -0.0 -0.3 -0.4 -2.1 0.9 1.4 -0.3
Sensitivity / hurt feelings 0.8 1.3 5.8 0.9 0.5 -0.1 -0.6 -0.0 2.4 2.1 0.3 0.3
Frequency of depressed mood in last 2 weeks 1.0 1.3 4.0 0.7 0.0 -1.3 2.0 -1.3 1.6 0.7 -0.9 -0.5
Hearing difficulty/problems: Yes 2.0 3.0 9.2 -1.1 3.0 2.1 1.0 2.2 -0.5 -1.1 -0.3 2.2
Relative age of first facial hair 0.2 0.4 1.3 -0.8 -0.0 -0.4 0.5 0.0 -0.5 0.9 1.1 -0.4
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 4.8 1.5 0.7 1.0 1.1 -0.3 -0.9 0.6 -2.2 1.2
Ever used hormone-replacement therapy (HRT) 0.4 0.5 2.2 0.6 1.5 0.4 0.6 -0.1 -0.5 0.4 0.4 1.1
Ever had hysterectomy (womb removed) 1.1 1.2 3.1 -0.0 1.6 1.0 -1.0 0.5 -1.6 0.5 0.3 1.8
Systolic blood pressure, automated reading 0.4 1.1 3.5 0.9 -0.6 -0.8 1.2 -1.3 -0.1 1.9 0.8 -0.8
Eye problems/disorders: Diabetes related eye disease 0.6 0.6 1.3 -1.0 -1.0 -0.1 0.4 -0.7 -0.3 -0.7 -1.1 -1.0
Angina 2.5 3.2 6.7 2.5 1.8 1.1 -0.4 2.4 2.6 2.0 -0.3 1.3
Medication for hormone replacement therapy 0.7 0.8 1.7 0.4 1.3 1.2 1.0 0.8 0.9 -0.8 0.5 1.0
Vitamin and mineral supplements 2.0 2.7 6.6 -0.7 1.3 1.5 -0.5 2.6 -2.5 -1.3 1.8 1.4
Supplements: Zinc 1.2 1.3 7.4 -0.7 -0.1 -0.5 1.7 -2.7 -0.6 -0.3 0.0 0.3
Medication: Co-codamol 1.6 1.8 3.6 0.8 1.3 1.3 1.2 1.6 0.8 -1.4 -1.9 1.3
Medication: Metformin 0.6 0.9 1.5 -0.2 1.1 0.9 1.1 1.0 -1.1 1.2 -0.9 0.6
Diabetes (father) 1.0 1.2 3.1 0.7 1.0 1.6 0.0 0.0 -0.9 -1.2 -1.2 1.8
Diabetes (mother) 0.8 1.0 3.7 -0.0 -0.5 -1.5 0.1 -0.8 -1.3 1.9 -0.0 -0.7
Severe depression (siblings) 0.5 0.6 2.2 0.9 1.0 -0.6 -0.3 -0.0 1.0 1.5 -0.1 0.4
Pack years adult smoking proportion 0.8 1.2 3.0 1.4 -0.6 -1.4 -0.3 -1.7 1.0 1.1 -0.8 -0.8
Impedance of leg (right) 0.3 1.7 6.4 2.5 1.2 0.6 0.3 1.1 0.6 1.9 0.5 1.2
Leg fat-free mass (left) 0.4 2.1 5.1 0.9 2.0 1.3 -1.3 -0.7 -1.8 1.4 -0.1 2.2
Trunk fat percentage 1.5 5.8 14.7 2.9 3.5 2.1 -1.7 0.1 -1.8 1.7 2.0 3.8
Hand grip strength (right) 0.3 0.7 2.3 1.5 0.8 0.5 0.9 -0.2 1.1 0.6 -0.8 0.4
Townsend deprivation index at recruitment 1.0 1.5 6.4 0.9 1.2 0.4 0.6 0.4 0.1 1.8 2.5 0.9
Current tobacco smoking 1.6 2.6 7.4 2.7 1.8 0.4 1.4 1.6 1.5 1.2 -1.8 1.1
Average weekly fortified wine intake 0.6 0.7 3.8 -1.0 -0.6 -0.3 -0.2 -0.3 -0.4 0.9 1.9 -0.2
Maternal smoking around birth 0.8 1.1 3.8 0.5 -1.1 -1.6 -0.2 -1.9 1.1 0.9 0.1 -0.8
Fed-up feelings 0.9 1.6 4.0 1.2 -0.0 -0.9 1.3 -1.9 1.5 2.0 0.3 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.6 2.1 5.4 1.9 2.3 0.6 1.8 0.6 1.2 0.4 -1.3 1.8
Relative age voice broke 0.5 0.7 2.0 -1.4 -0.8 -1.0 -0.8 -0.2 -0.1 0.7 0.4 -1.3
Taking other prescription medications 3.0 4.6 10.2 2.5 2.9 2.7 0.7 3.2 -0.3 -0.0 -0.7 2.9
Age when periods started (menarche) 0.7 1.7 7.5 -0.1 1.1 2.2 -0.3 2.7 -0.7 -0.8 0.4 0.9
Bilateral oophorectomy (both ovaries removed) 1.3 1.5 2.9 -1.1 1.6 1.6 0.8 0.9 -1.3 0.4 0.8 1.7
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 2.8 1.7 -0.3 -0.6 1.2 0.5 1.1 1.0 -1.0 -0.8
Tinnitus: Yes, but not now, but have in the past 0.9 1.0 2.2 1.1 0.9 1.0 1.4 0.9 0.4 0.9 -0.2 1.5
Qualifications: CSEs or equivalent 0.4 0.6 1.5 -0.3 0.9 -0.2 -1.1 -1.2 0.3 0.8 0.3 0.8
Serious illness, injury or assault to yourself 0.6 0.8 1.6 0.9 1.0 0.3 -1.0 0.1 1.1 1.3 -0.8 0.8
High blood pressure 0.6 1.6 6.0 1.6 1.6 0.8 -0.1 0.3 0.7 2.5 0.6 1.2
Hayfever, allergic rhinitis or eczema 0.2 0.4 1.3 -0.2 -0.6 -0.5 0.2 -1.1 -0.4 -0.6 0.5 -0.6
Multivitamins +/- minerals 0.8 1.1 2.0 0.3 -1.2 -1.2 0.3 -0.6 1.4 1.0 -1.3 -1.3
Stomach or abdominal pain in last month 0.7 0.8 4.9 -0.1 0.5 -0.3 0.7 -0.8 -0.9 -0.3 -2.2 0.2
Supplements: Glucosamine 1.9 2.5 10.1 -1.3 -1.9 -1.4 0.1 -3.2 -0.1 1.2 1.6 -1.3
Diverticular disease/diverticulitis (self-reported) 2.1 2.5 11.8 -0.2 -1.1 -2.0 -1.4 -0.7 0.8 3.4 0.5 -1.6
Medication: Atenolol 1.2 1.6 4.2 0.1 -0.0 -1.2 -1.5 -1.6 1.2 2.0 1.3 -0.5
Medication: Levothyroxine sodium 0.8 1.3 3.5 -1.8 -1.6 -0.6 -0.2 -1.2 -0.7 -1.9 0.1 -0.5
Sitting height 0.5 3.8 8.7 1.9 2.6 1.9 -0.7 0.1 -2.4 2.2 0.2 3.0
Chronic bronchitis/emphysema (father) 0.8 0.9 2.3 -0.3 -1.1 -1.5 -1.2 -0.8 1.2 0.3 0.4 -1.1
High blood pressure (mother) 0.2 0.3 1.3 0.2 0.2 0.6 -0.4 -0.6 0.3 1.1 0.2 0.3
Body mass index (BMI) 0.3 1.2 3.2 0.7 1.8 0.7 -0.7 -1.3 -0.8 0.2 1.0 1.7
Impedance of leg (left) 0.1 0.7 2.3 1.5 0.4 0.2 -0.1 0.9 0.5 1.2 0.9 0.5
Leg predicted mass (left) 0.4 2.2 5.2 0.8 2.0 1.4 -1.3 -0.7 -1.9 1.4 -0.2 2.3
Trunk fat mass 1.4 6.2 15.7 2.9 3.7 2.2 -1.8 -0.1 -1.9 2.0 1.6 4.0
Waist circumference 0.8 3.1 7.8 2.1 2.8 1.2 -1.0 -0.9 -0.7 1.7 1.0 2.8
Number of incorrect matches in round 1.6 2.6 6.9 0.1 -0.9 -2.6 0.2 -2.4 2.2 1.3 1.2 -1.3
Past tobacco smoking 0.6 1.0 2.2 -0.7 -1.5 -0.0 -1.0 0.8 -0.9 -1.0 -1.1 -1.3
Alcohol usually taken with meals 2.0 3.3 6.6 -1.9 -2.6 -1.9 -2.1 -2.5 0.2 -0.9 0.5 -2.0
Nervous feelings 0.9 1.8 4.9 2.1 0.1 -0.2 1.9 0.0 2.2 1.5 -0.8 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.3 3.1 1.6 -0.4 -1.1 1.8 -1.5 1.2 0.3 0.1 -0.6
Hearing difficulty/problems with background noise 0.8 1.3 3.8 -0.8 1.9 1.0 1.3 1.5 0.1 -1.1 -0.2 1.1
Hair/balding pattern: Pattern 2 0.4 0.5 3.0 -0.7 0.3 0.6 -0.1 -0.1 0.5 -1.7 -0.5 -0.0
Had menopause 0.3 0.4 2.4 -0.4 0.4 -0.3 0.4 1.6 -0.0 0.2 -0.4 -0.2
Had other major operations 0.6 0.7 2.3 0.6 0.9 1.1 0.7 1.5 0.0 -0.2 -0.3 0.9
Forced vital capacity (FVC) 0.2 0.8 3.1 -0.0 0.5 0.9 -1.8 -0.1 -0.4 1.4 0.8 0.8
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 3.3 1.3 -0.3 -0.3 1.4 -0.5 0.0 0.5 -1.8 -0.3
Ever unenthusiastic/disinterested for a whole week 0.6 0.8 2.4 -0.8 0.7 -0.5 1.6 -0.5 1.0 -0.6 -1.2 0.4
Qualifications: None of the above 1.0 2.0 5.2 0.7 1.9 1.1 2.3 0.3 0.2 -1.9 -0.8 1.8
Financial difficulties in last 2 years 0.5 0.7 1.5 -0.9 1.2 0.5 0.9 -0.5 1.0 -0.8 0.2 0.8
Mouth/teeth dental problems 0.8 1.2 5.4 -0.5 -1.7 -0.2 2.3 -0.4 -0.8 -0.5 0.8 -0.8
Heart attack 0.7 0.9 2.8 1.0 1.7 1.1 0.1 0.2 0.3 0.2 0.6 1.5
Allergy 0.2 0.4 2.2 -1.5 -0.4 0.3 -0.5 -0.2 0.4 -0.1 0.5 -0.3
Pain all over the body in last month 0.7 0.8 1.5 1.2 1.0 1.1 0.5 1.1 0.7 0.9 -0.1 0.9
Diabetes (self-reported) 0.2 0.3 1.5 -0.0 0.2 0.4 0.7 -0.0 -0.8 1.2 -0.4 0.4
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 1.1 0.5 -0.0 0.1 -0.5 1.0 1.0 -0.9 -0.3 -0.4
Medication: Ramipril 0.9 1.1 2.5 1.5 -1.4 -1.6 0.6 -1.4 0.0 -0.1 0.1 -1.0
Medication: Simvastatin 0.5 0.8 1.7 1.3 1.3 0.3 -1.2 0.4 0.9 0.4 -1.1 0.5
Fluid intelligence score 1.6 3.3 15.7 -0.3 -1.0 0.4 -4.0 2.1 -2.2 1.6 0.3 -0.9
Illnesses of siblings 0.5 0.7 3.3 -0.5 -0.9 -0.3 0.8 -1.1 -1.8 -0.1 0.5 -0.4
Neuroticism score 1.1 2.3 6.1 1.5 0.5 -0.6 1.3 -2.0 2.1 2.5 -1.4 0.2
Weight 0.8 3.8 10.8 2.0 3.1 1.8 -1.2 -0.7 -1.6 1.4 0.7 3.3
Impedance of arm (right) 0.8 3.8 10.8 3.2 1.9 1.8 0.2 3.3 0.1 1.0 0.8 2.2
Arm fat percentage (right) 0.9 3.7 10.5 2.0 3.2 1.9 -1.0 0.2 -1.0 0.8 1.5 3.2
Trunk fat-free mass 0.2 1.4 2.3 0.4 1.4 0.9 -0.8 -1.1 -1.5 1.4 -0.9 1.5
Hip circumference 0.7 3.0 7.1 2.2 2.5 1.0 -1.1 -1.4 -1.1 1.5 1.1 2.7
Time employed in main current job 0.5 0.6 2.1 -1.4 0.2 0.2 -0.5 0.3 -0.7 -1.5 -0.6 -0.3
Alcohol intake versus 10 years previously 1.0 1.5 3.0 0.3 1.5 -0.3 1.7 -1.7 0.9 0.8 1.5 1.0
Father’s age at death 0.6 0.8 3.1 0.1 1.0 0.2 1.8 0.3 1.0 -0.8 -1.2 0.5
Worrier / anxious feelings 1.4 2.6 12.5 1.7 0.6 -1.1 -0.5 -0.7 2.4 3.5 -0.2 -0.2
Frequency of tiredness / lethargy in last 2 weeks 2.2 3.5 8.3 2.1 2.7 1.5 2.9 -0.1 0.9 -0.2 -1.4 2.6
Falls in the last year 1.4 1.9 6.2 0.6 2.5 1.8 -0.1 1.3 0.1 1.2 -0.3 2.0
Hair/balding pattern: Pattern 3 0.2 0.3 1.1 -0.9 -0.2 0.3 -0.7 -0.3 -0.6 -0.1 1.0 -0.0
Number of live births 0.6 0.8 2.0 -1.1 -1.0 -1.0 -1.4 -0.9 0.0 0.6 0.6 -0.9
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 2.2 -0.8 -0.3 0.6 -1.5 -0.9 -1.0 1.0 0.7 0.4
Pulse rate 0.2 0.3 1.2 0.4 0.3 0.1 -0.9 0.5 0.1 0.2 1.1 -0.1
Happiness 0.4 0.5 1.3 0.6 1.0 0.0 1.1 0.4 0.7 -0.4 -1.0 0.4
Noisy workplace 1.9 2.3 6.2 0.1 -0.5 -2.5 0.9 -2.5 2.2 -0.9 0.2 -1.3
Qualifications: A levels/AS levels or equivalent 0.8 1.9 4.2 -1.8 -1.6 -0.6 -2.1 0.6 -0.6 1.3 0.8 -1.9
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 3.2 -1.1 0.4 1.0 -1.8 0.1 -1.0 0.7 0.7 1.1
Mouth/teeth dental problems: Dentures 1.2 2.1 5.7 1.7 2.2 1.3 -0.9 2.4 0.4 0.4 0.2 1.5
Asthma 1.6 3.2 9.3 3.0 2.1 1.3 1.6 2.1 0.4 0.1 -1.8 1.8
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.1 -1.1 -0.2 -0.4 -0.1 -0.9 1.0 -0.2 -0.3 -0.6
Medication: Cholesterol lowering 0.3 0.5 1.7 1.0 0.6 -0.3 -1.1 0.4 1.3 0.4 0.2 -0.0
Depression (self-reported) 1.7 2.1 4.6 2.1 2.0 1.1 1.8 0.4 0.0 -0.4 -1.0 2.0
Medication: Lansoprazole 0.5 0.6 1.3 0.9 1.1 0.6 -1.0 0.3 -0.3 0.5 0.7 1.1
Prospective memory result 0.5 0.7 1.7 0.7 1.2 -0.1 1.3 -0.6 0.7 -0.5 0.5 1.1
Lung cancer (father) 0.1 0.2 0.5 0.7 -0.4 -0.5 -0.1 0.5 0.1 0.0 -0.4 -0.2
Illnesses of mother 1.9 2.3 7.8 -2.8 -1.6 -1.3 -1.1 -0.5 0.3 -1.0 1.7 -1.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.0 3.3 -0.2 0.5 1.1 -1.8 0.4 -0.9 1.3 0.9 0.7
Pulse wave Arterial Stiffness index 0.7 0.8 5.6 0.2 0.1 -0.2 0.9 -0.5 -2.4 0.6 -0.4 0.3
Impedance of arm (left) 0.9 4.2 11.0 3.2 2.3 2.0 0.1 3.3 -0.1 0.8 0.7 2.5
Arm fat mass (right) 0.7 3.0 8.1 1.8 2.8 1.3 -1.1 -0.6 -1.3 1.2 1.0 2.8
Trunk predicted mass 0.2 1.4 2.5 0.3 1.5 1.0 -0.8 -1.0 -1.6 1.3 -0.9 1.6
Standing height 0.6 6.2 14.5 3.0 3.1 2.6 -1.3 1.4 -2.3 2.7 -0.7 3.8
Length of working week for main job 3.9 4.3 10.0 -1.4 -2.6 -3.0 -0.9 -3.2 -0.7 0.8 1.8 -2.5
Exposure to tobacco smoke at home 1.0 1.1 2.1 1.1 1.3 0.6 0.7 1.2 1.4 1.2 1.1 0.7
Breastfed as a baby 1.6 2.0 7.1 -1.1 -0.2 -0.7 1.9 0.7 -0.0 -2.1 -2.7 -0.9
Tense / ‘highly strung’ 0.6 1.0 4.2 1.4 1.1 -0.4 0.2 -0.6 2.0 1.1 0.0 0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 2.0 3.1 14.1 3.8 2.4 0.7 1.1 0.8 0.9 0.9 -1.0 1.6
Hair/balding pattern: Pattern 4 0.2 0.4 1.2 0.3 1.0 0.4 -0.2 0.0 -0.4 -0.2 0.8 1.1
Birth weight of first child 0.7 1.3 4.4 -0.9 -1.4 -0.9 -2.1 -1.1 -0.9 0.5 1.1 -0.9
Peak expiratory flow (PEF) 0.6 1.4 4.5 -0.8 1.0 2.1 0.7 -0.2 -1.6 -0.1 0.6 1.6
Pulse wave reflection index 1.0 1.3 5.2 -0.9 -0.3 -0.3 1.6 -0.6 -2.3 -1.1 -1.1 -0.1
Ever highly irritable/argumentative for 2 days 1.2 1.5 4.6 -0.0 2.1 0.8 0.5 1.0 -0.4 -0.2 1.7 1.9
Loud music exposure frequency 1.7 1.9 3.8 -1.2 1.9 1.5 1.9 1.0 -0.6 -0.4 0.8 1.9
Qualifications: O levels/GCSEs or equivalent 0.9 1.4 4.5 -2.1 -1.7 -0.6 -0.9 0.3 -0.1 1.0 1.1 -1.4
Mouth/teeth dental problems: Bleeding gums 0.6 0.7 2.3 -0.3 0.4 -0.5 -1.5 -0.8 1.4 -0.1 -1.1 -0.1
Blood clot in the leg (DVT) 0.4 0.6 2.2 -1.0 -0.0 -0.5 -1.2 -0.3 -0.2 1.5 0.3 -0.1
Medication: Paracetamol 0.9 1.5 3.9 1.7 1.1 0.4 -0.5 1.3 0.7 1.6 -2.0 0.6
Headache pain in last month 1.1 1.8 3.9 -0.2 -0.7 -1.6 -0.6 -1.9 2.0 1.8 -0.0 -1.4
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 1.3 -1.1 -0.9 -0.5 0.8 -1.0 -0.9 -1.1 -0.3 -0.4
Glaucoma (self-reported) 1.7 2.0 5.9 -1.3 -2.4 -0.9 -1.6 0.5 -1.5 0.3 0.2 -2.0
Gout (self-reported) 0.7 1.0 2.7 0.8 0.6 0.8 1.6 -1.3 0.1 -1.6 -0.4 0.5
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 1.6 -1.1 -0.7 0.3 -0.2 0.2 0.2 -1.3 0.8 0.3
Medication: Amlodipine 0.6 0.9 2.3 1.1 -0.4 1.0 -0.6 1.5 1.2 0.8 0.8 0.1
Medication: Ventolin 100micrograms inhaler 0.4 0.5 4.0 2.0 -0.1 -0.4 0.1 0.1 -0.5 -0.3 0.3 -0.3
Birth weight 0.3 0.6 1.7 1.3 1.1 0.8 0.0 0.5 0.4 0.4 0.4 1.0
Chronic bronchitis/emphysema (mother) 1.3 1.5 11.3 3.4 0.1 -0.2 0.3 -0.2 0.6 0.4 -1.1 0.3
High blood pressure (siblings) 0.3 0.5 3.4 -0.3 0.0 -0.5 -0.4 -0.3 1.8 -0.2 0.1 -0.4
Forced vital capacity (FVC), Best measure 0.5 1.7 3.7 0.7 1.3 1.7 -1.9 1.1 -0.4 1.4 1.1 1.4
Body fat percentage 1.3 5.0 12.8 2.8 3.4 1.9 -1.4 -0.2 -1.3 1.5 1.7 3.6
Leg fat percentage (right) 0.8 2.9 7.4 2.0 2.6 1.4 -0.9 -1.0 -0.8 1.2 1.5 2.7
Arm fat-free mass (right) 0.3 1.3 3.4 0.2 1.0 0.3 -1.2 -1.9 -1.5 1.5 -0.6 1.2
Exposure to tobacco smoke outside home 0.2 0.3 1.2 -0.6 -0.1 -1.1 0.2 -0.7 -0.2 -0.1 0.1 -0.6
Comparative body size at age 10 0.4 1.2 4.0 -1.0 0.3 1.1 0.7 -0.5 -2.0 -0.0 1.8 0.9
Number of full brothers 1.5 1.9 4.6 0.7 2.1 1.2 1.9 1.4 0.2 -1.0 -1.3 1.5
Worry too long after embarrassment 1.5 2.5 6.9 -0.0 -0.8 -1.1 2.6 -1.1 1.8 1.9 -1.7 -1.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.7 2.2 1.5 1.0 -0.5 0.0 0.3 1.4 0.6 -0.8 0.1
Wheeze or whistling in the chest in last year 0.4 0.7 3.2 0.2 0.8 -0.8 0.4 -0.5 1.0 -0.8 -1.8 0.0
Number of children fathered 0.3 0.3 1.1 -0.7 0.4 -0.1 -0.5 1.1 0.4 -0.3 1.0 0.2
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.7 4.8 1.5 -0.7 -1.4 0.0 -0.4 1.9 2.2 -0.8 -1.3
Age at first live birth 0.1 0.2 0.7 -0.0 -0.3 0.2 -0.8 0.2 0.8 -0.4 0.2 -0.4
Pulse wave peak to peak time 0.7 0.9 5.6 0.1 0.1 0.4 -1.1 0.7 2.4 -0.2 0.5 -0.1
Health satisfaction 1.0 1.3 2.4 1.6 1.2 1.2 1.3 0.4 0.3 -1.3 -1.2 1.4
Shortness of breath walking on level ground 2.8 3.3 6.1 0.8 -0.8 -2.2 2.4 -2.2 2.0 -1.2 -2.5 -1.1
Qualifications: College or University degree 0.2 0.8 1.9 -0.2 -0.8 0.5 -1.3 1.4 -0.9 0.7 1.0 -0.5
Eye problems/disorders: None of the above 0.8 0.9 5.6 -0.9 -0.3 0.0 0.7 -0.9 -0.5 -0.1 2.4 0.4
Mouth/teeth dental problems: Loose teeth 0.2 0.2 0.7 -0.9 0.1 -0.2 -0.8 0.2 -0.5 0.3 -0.5 -0.1
Emphysema/chronic bronchitis 1.4 1.6 6.1 2.0 1.0 0.2 2.5 1.5 -0.2 0.1 -0.6 0.6
Medication for pain relief, constipation, heartburn 1.5 2.5 9.2 -2.0 -1.4 -0.6 1.7 -1.0 -1.3 -3.0 0.7 -1.1
Neck or shoulder pain in last month 0.9 1.3 3.7 0.2 1.1 -0.3 1.7 -1.2 1.4 0.8 -1.9 0.6
Medication: Blood pressure 0.4 0.7 1.6 1.3 0.4 0.7 -0.1 1.1 1.0 1.2 -0.6 0.3
Angina (self-reported) 2.6 3.4 6.7 2.5 1.9 1.1 -0.5 2.4 2.6 2.2 -0.1 1.3
Migraine (self-reported) 0.6 0.7 2.0 -0.7 1.0 -0.5 -1.0 -0.7 0.2 1.1 1.4 0.3
Medication: Ibuprofen 0.6 0.7 1.6 -1.3 -0.8 -0.8 0.4 -1.0 0.9 -0.3 -0.7 -0.9
Medication: Allopurinol 0.6 0.8 2.0 0.8 0.9 0.7 1.4 -0.8 0.1 -1.1 -0.9 0.8
Medication: Omeprazole 3.2 3.8 9.6 2.4 2.4 2.9 0.8 1.4 -1.3 0.4 0.2 3.1
Medication: Seretide 50 evohaler 1.8 2.1 4.5 0.1 -1.3 -2.0 0.2 -0.3 2.0 -1.5 -1.5 -2.1
Mean time to correctly identify matches 0.8 1.6 5.7 0.3 0.4 0.6 2.4 1.4 -0.1 -1.3 -2.1 0.4
Heart disease (mother) 0.6 0.8 1.6 -0.5 0.7 1.0 -0.6 0.8 -0.7 -0.7 1.1 1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 1.5 -1.0 -0.6 0.3 -0.9 0.3 -0.2 -1.2 1.1 -0.1
Whole body fat mass 1.2 5.1 13.2 2.5 3.6 2.0 -1.5 -0.4 -1.7 1.7 1.2 3.6
Leg fat mass (right) 0.9 3.4 8.7 2.2 2.8 1.5 -1.1 -1.0 -1.3 1.4 0.9 3.0
Arm predicted mass (right) 0.3 1.4 3.4 -0.1 1.1 0.4 -1.2 -1.7 -1.8 1.4 -0.2 1.3
Pulse rate, automated reading 0.2 0.7 5.6 -0.0 -0.0 0.5 -0.4 0.4 -2.4 -0.5 0.2 -0.2
Alcohol intake frequency. 0.3 0.6 2.4 1.6 0.3 -1.1 0.4 -0.4 0.5 1.1 0.2 -0.2
Comparative height size at age 10 1.3 7.1 18.7 3.2 3.7 3.0 -1.0 1.7 -1.4 2.4 -0.9 4.3
Number of full sisters 0.9 1.1 2.9 0.2 1.1 1.2 1.5 -0.4 0.2 -1.4 -0.2 1.7
Suffer from ‘nerves’ 1.5 2.3 7.7 2.8 1.6 0.9 1.6 0.4 1.0 1.8 -1.2 1.4
Overall health rating 1.5 3.1 11.3 3.4 1.7 -0.2 1.1 -0.1 2.4 0.6 -2.4 0.8
Chest pain or discomfort 0.8 1.1 2.8 1.6 0.9 0.5 0.1 1.1 0.0 1.7 -1.3 0.8
Had major operations 1.6 1.8 5.1 2.3 1.1 0.1 1.6 -0.1 1.5 -0.5 -2.2 0.2
Age at last live birth 0.8 1.2 3.5 -1.6 -0.9 0.3 -1.9 -1.4 -0.4 -0.6 1.1 -0.2
Family relationship satisfaction 0.3 0.4 1.5 0.7 0.5 0.1 1.2 -0.2 -0.3 -0.0 -1.1 0.4
Leg pain on walking 0.8 1.0 4.2 -0.6 0.5 -0.8 -0.8 -1.1 1.0 -1.0 -2.0 -0.0
Qualifications: NVQ or HND or HNC or equivalent 0.8 0.9 2.5 0.7 -0.4 -1.6 1.3 -1.2 0.9 0.0 -0.9 -0.7
Commuting to job workplace: Car/motor vehicle 2.5 2.8 6.2 0.7 -2.1 -2.5 0.9 -2.4 0.4 0.5 -1.9 -1.8
Illness, injury, bereavement, stress in last 2 years 0.4 0.4 1.4 0.0 -0.7 -0.4 1.0 -0.1 -1.2 0.7 -0.0 -0.7
Medication: Aspirin 2.0 2.6 9.2 2.4 1.4 1.0 -0.5 1.6 0.5 3.0 1.2 1.1
Supplements: Vitamin C 2.2 2.6 13.3 -1.3 -0.9 -1.7 -0.8 -3.6 1.1 1.1 0.7 -1.1
Knee pain experienced in last month 0.8 1.2 5.8 1.1 0.5 0.1 1.0 0.6 2.4 1.6 0.3 0.2
Hypertension (Self-reported) 0.3 1.0 4.3 1.4 0.9 0.5 -0.1 0.0 0.8 2.1 0.5 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.7 2.0 7.8 2.8 0.9 0.2 0.6 0.8 2.5 0.4 -1.2 0.6
Illnesses of father: Heart disease 0.6 0.8 2.3 -1.1 -0.7 0.0 -1.2 -0.7 -1.2 -0.6 1.5 0.0
Illnesses of siblings: Diabetes 0.7 0.8 2.6 -0.9 1.3 1.0 -0.0 1.6 0.7 -0.3 -0.5 0.8
Smoking status: Previous 0.8 1.3 3.9 -0.2 1.1 0.1 0.1 -1.6 0.9 1.3 2.0 1.1
Forced expiratory volume in 1-second (FEV1), predicted 2.0 4.2 9.9 0.5 2.1 3.0 -1.2 1.4 -3.0 0.1 1.3 3.1
Whole body fat-free mass 0.2 1.4 2.9 0.3 1.4 0.8 -1.0 -1.2 -1.7 1.3 -0.6 1.5
Leg fat-free mass (right) 0.3 1.3 3.4 0.2 1.4 1.0 -1.3 -0.8 -1.9 0.7 -0.1 1.7
Arm fat percentage (left) 1.0 4.0 10.9 2.2 3.3 1.9 -1.1 -0.0 -1.1 0.9 1.5 3.3
Average weekly red wine intake 0.9 1.3 2.9 0.7 -1.3 -1.4 -0.7 -1.1 0.0 0.9 -1.7 -1.4
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.2 0.1 0.1 -0.0 0.4 0.2 -0.2 0.3 -0.4 -0.0
Mood swings 0.8 1.4 3.3 1.0 1.6 0.5 1.8 -1.0 1.5 0.6 -1.0 1.1
Loneliness, isolation 1.4 1.9 4.8 2.2 1.3 -0.2 -0.4 0.7 1.6 1.8 -2.0 0.3
Long-standing illness, disability or infirmity 0.8 1.2 3.2 1.6 1.8 0.7 0.3 0.1 0.2 0.7 -1.4 1.3
Ever had bowel cancer screening 1.2 1.4 5.0 1.0 0.8 0.2 1.6 1.0 1.5 -0.5 -2.2 0.4
Diabetes diagnosed by doctor 0.3 0.5 2.2 -0.2 0.2 0.5 0.2 0.0 -1.4 1.5 -0.6 0.4
Ever had stillbirth, spontaneous miscarriage or termination 1.7 1.8 3.6 -0.5 -1.5 -1.9 -0.6 -1.8 0.8 0.9 1.6 -1.6
Friendships satisfaction 0.3 0.4 1.9 -0.7 0.2 0.2 0.4 1.4 0.5 0.2 -0.4 -0.4
Qualifications: nursing, teaching 0.6 0.9 2.3 0.6 -0.7 -1.1 -1.0 -0.2 1.1 1.5 0.6 -1.2
Commuting to job workplace: Walk 0.7 0.8 2.4 -0.8 -0.1 0.6 -1.5 0.3 -1.2 0.4 1.3 0.3
Eye problems/disorders: Cataract 0.8 1.0 2.2 1.2 1.4 0.8 0.5 0.9 0.3 0.4 -1.5 1.1
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 1.3 -0.0 0.6 0.5 0.2 -1.1 -0.7 -0.0 -1.1 0.8
Medication for cholesterol 1.7 2.5 6.9 -0.5 -2.6 -2.3 -1.0 -1.1 1.1 0.5 -0.2 -2.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.9 2.3 4.0 2.0 2.0 0.8 -0.7 1.6 1.4 1.6 -1.2 1.7
Back pain experienced in last month 0.6 0.8 3.1 0.0 0.4 0.5 1.4 -1.8 1.1 0.5 0.4 0.7
Mineral and other dietary supplements 1.1 1.4 6.8 0.1 1.5 1.3 -0.4 2.6 -0.6 -0.8 -0.2 0.8
Breast cancer (self-reported) 0.5 0.6 1.9 -0.0 0.3 1.4 0.6 1.0 -0.3 -0.8 -0.8 0.6
Asthma (self-reported) 1.7 3.3 10.1 3.2 2.1 1.3 1.5 2.1 0.6 0.1 -2.1 1.7
Osteoporosis (self-reported) 1.0 1.3 7.1 0.7 -1.4 -0.9 -0.2 -0.7 -0.3 0.0 -2.7 -0.8
Osteoarthritis (self-reported) 0.8 1.0 2.2 0.5 0.8 0.6 -1.1 1.1 1.5 1.4 0.9 0.7
Medication: Aspirin 2.1 2.8 9.0 2.4 1.4 1.0 -0.9 1.8 0.6 3.0 1.2 1.2
Medication: Gliclazide 0.8 0.9 5.2 -0.2 0.6 0.1 -0.5 0.5 -1.3 2.3 0.3 0.5
Illnesses of father: None of the above (group 1) 0.5 0.6 1.2 0.2 0.9 0.7 0.2 0.8 -1.0 0.2 -1.1 0.9
Smoking status: Current 1.5 2.4 5.9 2.4 1.5 0.3 1.8 1.6 1.6 0.9 -1.9 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.2 2.6 7.7 -2.8 0.2 1.2 -2.6 -0.8 -0.9 -0.4 2.2 0.8
Whole body water mass 0.2 1.4 2.7 0.3 1.5 0.8 -1.1 -1.2 -1.6 1.2 -0.6 1.6
Leg predicted mass (right) 0.3 1.4 3.5 0.2 1.4 1.0 -1.3 -0.9 -1.9 0.8 -0.1 1.7
Arm fat mass (left) 0.8 3.4 9.4 1.9 3.1 1.7 -1.2 -0.4 -1.4 1.1 0.9 3.1
Number of self-reported non-cancer illnesses 1.4 2.5 5.4 2.2 2.3 1.7 0.4 1.6 0.3 -0.3 -1.4 2.2
Average weekly champagne plus white wine intake 0.5 0.7 2.8 -0.0 -0.1 0.4 -1.7 1.0 0.2 1.2 0.8 -0.3
Miserableness 0.7 1.3 5.8 1.2 0.7 -0.1 1.6 -1.1 0.3 -0.1 -2.4 0.4
Guilty feelings 1.3 2.0 6.1 2.2 -0.0 -0.4 1.5 0.1 1.1 1.7 -2.5 -0.3
Wears glasses or contact lenses 0.7 0.8 2.2 1.1 0.5 -0.4 -0.4 1.1 1.2 -0.7 -1.5 -0.3
Ever taken oral contraceptive pill 0.6 0.7 1.5 0.9 0.8 1.2 0.4 0.9 0.6 0.7 0.7 0.9
Hearing aid user 2.8 3.2 9.5 -0.3 3.1 2.3 -0.7 2.9 -0.3 -0.1 0.3 2.2
Mother’s age at death 0.9 1.1 3.9 1.0 0.9 0.5 -1.1 1.5 -0.1 0.0 -2.0 0.6
Financial situation satisfaction 0.3 0.4 1.5 -0.2 1.2 -0.0 -0.1 -0.1 0.5 0.2 1.2 0.7
Tinnitus: Yes, now most or all of the time 0.6 0.7 2.4 -0.6 1.2 0.2 -0.1 -0.2 -1.6 -0.5 1.0 0.5
Commuting to job workplace: Public transport 1.9 2.2 10.5 0.5 1.4 2.1 -0.1 3.2 0.9 -0.9 -0.6 0.9
Eye problems/disorders: Glaucoma 1.2 1.5 3.5 -0.9 -1.5 -0.3 -1.5 1.6 -1.9 0.2 0.2 -1.3
Medication: Blood pressure 0.1 0.2 0.6 0.5 0.8 0.3 -0.2 -0.4 0.1 0.0 0.3 0.6
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.8 1.4 0.7 0.3 0.5 -1.1 1.3 1.2 -0.6 0.9
Supplements: Fish oil (including cod liver oil) 0.8 1.0 4.6 -0.8 -1.2 -1.1 -0.3 -2.1 0.5 0.1 0.1 -0.7
High cholesterol (Self-reported) 0.1 0.2 0.6 0.1 0.3 0.2 -0.6 -0.3 -0.2 0.7 0.2 0.4
Medication: Bendroflumethiazide 0.8 1.2 4.0 0.5 2.0 1.1 -0.5 0.3 0.3 1.1 1.1 1.7
Medication: Paracetamol 0.9 1.4 3.3 1.4 0.8 0.3 -0.6 1.5 0.7 1.8 -1.8 0.6
Medication: Lisinopril 0.5 0.7 1.7 0.8 1.3 0.4 -0.4 -0.7 0.8 1.2 0.4 0.6
Medication: Atorvastatin 0.3 0.4 2.0 -0.3 0.4 0.3 -0.3 0.0 -1.4 0.5 0.7 0.6
Illnesses of father: High blood pressure 1.1 1.4 4.6 0.1 -1.2 -1.1 0.3 -0.0 2.1 1.3 0.1 -1.9
Alcohol drinker status: Never 0.5 0.6 2.5 0.9 -0.3 -0.1 0.1 1.6 -0.5 -0.2 -1.1 -0.4
Ever smoked 0.7 1.2 3.7 1.1 1.0 -0.9 0.6 -0.6 1.7 1.9 0.5 0.4
Basal metabolic rate 0.3 1.9 4.1 0.6 1.8 1.0 -1.2 -1.3 -1.8 1.5 -0.1 2.0
Leg fat percentage (left) 0.6 2.1 5.2 1.4 2.1 1.1 -1.3 -1.1 -1.0 0.6 1.5 2.3
Arm fat-free mass (left) 0.3 1.4 2.5 -0.1 1.3 0.6 -1.2 -1.5 -1.6 1.2 -0.7 1.4
Number of operations (self-reported) 0.6 0.9 3.0 1.2 1.7 0.6 0.4 0.3 0.7 0.5 -0.8 1.3
Average weekly beer plus cider intake 0.9 1.4 3.8 -0.4 1.5 -1.2 -0.2 -0.4 1.9 1.3 1.6 0.1
Irritability 0.9 1.5 5.8 0.2 0.9 0.9 1.3 -2.4 0.3 -1.2 0.7 1.6
Risk taking 1.9 2.8 6.3 1.1 2.5 1.4 -0.1 1.5 1.4 1.7 1.8 2.2
Ever had prostate specific antigen (PSA) test 1.1 1.2 2.2 1.2 1.5 0.6 -0.5 1.3 1.1 0.1 -1.4 1.3
Fractured/broken bones in last 5 years 0.6 0.7 2.4 0.3 -0.8 -0.2 -1.5 0.3 -1.2 1.3 0.3 -0.5
Age started oral contraceptive pill 0.3 0.4 0.9 -1.0 -0.1 -0.4 0.4 0.9 0.4 -0.6 -0.6 -0.6
Diastolic blood pressure, automated reading 0.2 0.7 1.2 0.8 1.0 0.2 1.1 -1.0 -0.9 1.1 0.2 0.5
Ever depressed for a whole week 0.5 0.6 1.6 -0.0 1.2 -0.1 0.7 -0.1 0.8 0.9 -1.3 0.7
Unable to work because of sickness or disability 0.3 0.5 1.6 0.9 0.5 -0.3 0.4 -1.3 -0.7 0.6 -0.2 0.4
Commuting to job workplace: Cycle 0.5 0.7 3.1 0.4 -0.6 -0.7 -1.2 -0.3 -0.1 1.8 -0.2 -0.7
Myopia 0.2 0.3 1.0 0.3 0.2 0.1 -0.7 -0.8 -0.3 -1.0 -0.0 0.2
Vascular/heart problems diagnosed by doctor 0.9 2.6 6.7 -2.2 -2.2 -0.8 0.0 -1.2 -1.8 -2.6 -0.5 -1.3
Cholesterol lowering medication 2.5 3.7 7.8 0.8 2.8 2.6 0.7 1.2 -1.9 -0.6 -2.2 2.7
Medication: Omeprazole (e.g. Zanprol) 3.5 4.3 10.4 3.1 2.7 2.8 0.4 1.4 -0.6 0.5 -0.8 3.2
Pain experienced in last month 1.5 2.5 8.9 -1.1 -0.9 0.6 -1.6 2.0 -3.0 -2.0 0.2 -0.4
Supplements: Calcium 1.1 1.2 6.1 -0.4 0.2 -0.2 2.0 -2.5 0.4 -0.2 -0.6 0.3
Basal cell carcinoma (self-reported) 0.9 1.1 2.7 -1.3 -0.8 0.8 0.7 0.8 -1.6 -1.4 1.1 0.3
Heart attack/myocardial infarction (self-reported) 0.7 0.9 3.2 0.9 1.8 1.1 0.1 0.4 0.4 0.1 0.6 1.5
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.4 -0.8 0.0 -0.4 -1.0 -0.7 -0.5 1.2 0.2 -0.0
Heart disease (siblings) 1.6 1.9 5.5 1.5 1.4 0.1 -2.3 0.3 2.2 1.2 -0.9 0.8
Alcohol drinker status: Previous 1.2 1.3 3.8 0.9 -0.4 -1.3 1.1 -0.4 1.9 -0.1 -1.7 -1.0
Pack years of smoking 0.6 0.9 2.2 1.3 -0.3 -1.2 -0.3 -1.5 0.7 1.2 -0.7 -0.5
Impedance of whole body 0.5 2.4 7.4 2.7 1.5 1.1 -0.0 2.4 0.3 1.3 0.8 1.8
Leg fat mass (left) 0.8 3.1 8.1 2.0 2.7 1.4 -1.3 -1.0 -1.3 1.1 1.1 2.8
Arm predicted mass (left) 0.3 1.5 3.5 0.1 1.2 0.6 -1.2 -1.5 -1.9 1.5 -0.5 1.4