Hub : Genes

STK10

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1400	0.0330	3.5e-05	0.077	0.043	0.083	0.073	0.086	1.1e-09	4.7e-06	2.4e-10	3.6e-09	1.1e-10
2	GTEx	Brain Cerebellum	0.3960	0.1070	4.3e-03	0.227	NA	0.232	NA	0.224	2.5e-07	NA	1.8e-07	NA	3.1e-07
3	GTEx	Esophagus Mucosa	0.1250	0.0480	5.9e-03	0.061	NA	0.019	NA	0.043	6.6e-05	NA	1.8e-02	NA	7.2e-04
4	GTEx	Prostate	0.3260	0.1060	3.6e-03	-0.008	NA	0.045	NA	0.000	5.7e-01	NA	2.8e-02	NA	3.3e-01
5	NTR	Blood	0.0240	0.0092	1.4e-03	0.003	0.009	0.006	0.009	0.003	2.8e-02	3.6e-04	3.0e-03	3.9e-04	2.8e-02
6	ROSMAP	Brain Pre-frontal Cortex	0.0835	0.0315	4.3e-03	0.030	0.014	0.036	0.027	0.035	7.3e-05	5.4e-03	1.7e-05	1.7e-04	2.1e-05
7	YFS	Blood	0.0762	0.0221	1.6e-05	0.000	0.012	0.010	0.013	-0.001	3.4e-01	7.9e-05	2.7e-04	3.1e-05	7.6e-01
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2010	0.0750	1.2e-03	-0.002	0.043	0.016	NA	-0.002	4.4e-01	1.7e-03	4.1e-02	NA	4.5e-01
9	TCGA	Brain Lower Grade Glioma	0.0768	0.0301	2.4e-04	0.018	0.038	0.045	NA	0.033	3.4e-03	3.1e-05	6.5e-06	NA	1.1e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.5	0.8	1.7	1.2	-0.3	0.8	-0.8	-0.6	0.6	-0.8	1.0	1.3
Bipolar Disorder or Schizophrenia	0.5	1.3	3.5	0.1	-1.5	0.8	-1.4	1.9	0.4	-1.0	0.3	1.3
Depressed Affect (Nagel 2018)	0.3	0.6	1.9	-0.0	-0.7	-1.2	-0.3	0.8	0.7	1.4	-0.3	0.1
Depression (Nagel 2018)	1.4	2.1	4.9	-1.7	-2.2	-2.0	-1.4	0.2	-1.0	1.4	0.1	-1.6
Intelligence (Savage-Jansen 2018)	0.4	1.2	3.8	0.0	0.7	1.4	0.9	-1.9	-0.1	-1.6	-0.6	0.9
Neuroticism (Nagel 2018)	0.4	0.9	2.2	0.0	-0.9	-0.7	-0.8	1.4	1.1	1.5	-0.3	0.7
Schizophrenia (2018)	0.8	1.7	8.0	-0.9	-1.7	0.4	-1.2	2.8	-0.7	-0.7	-0.4	0.7
Schizophrenia vs Biploar Disorder	0.4	0.6	1.4	-0.4	0.0	1.0	0.5	1.2	-1.0	-0.7	0.9	0.3
Worry (Nagel 2018)	0.4	0.9	2.3	0.7	0.2	-0.1	-1.5	1.5	1.0	0.8	-0.9	0.8
Alzheimer’s Disease (in mother)	0.3	0.4	1.8	-0.4	0.6	-0.6	-0.4	0.6	-0.5	0.2	-1.4	-0.2
Alzheimer’s Disease (in father)	0.5	0.6	1.9	-0.3	0.8	-0.7	-1.1	0.3	-0.6	0.7	-1.4	-0.3
Alzheimer’s Disease (including proxy)	0.6	0.9	2.5	-0.9	0.7	-0.8	0.0	0.9	-1.1	0.9	-1.6	-0.5
Crohns Disease (2017)	1.4	3.1	10.6	-3.0	3.2	0.1	-0.4	-0.7	-1.8	-0.6	-0.8	-1.9
Irritable Bowel Disease (IBD)	2.2	5.2	17.3	-4.2	2.4	-0.9	-1.3	-0.0	-3.2	-0.8	-1.3	-3.0
Ulcerative Colitis (UC)	2.0	3.8	11.0	-3.3	0.8	-1.4	-1.5	-0.0	-3.0	-0.6	-1.3	-2.8
Major Depression (MDD)	0.9	1.1	2.4	-1.1	-0.1	-1.1	0.4	-0.4	-0.9	1.5	-1.5	-1.3
Reaction Time	0.4	0.7	1.8	0.7	-0.1	0.8	0.9	-1.4	-0.2	-0.3	1.2	1.0
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.6	-0.8	1.1	0.5	0.1	-1.2	-0.5	-0.5	-0.7	-0.4
Breast Cancer	1.4	3.3	6.4	-2.5	-1.0	-1.2	-2.1	2.3	-0.9	1.3	-2.5	-1.5
Ovarian Cancer	3.0	3.9	11.9	-3.4	-0.8	-0.9	0.7	2.3	-3.0	-0.1	-0.6	-2.6
Prostate Cancer	0.4	0.6	2.1	-0.4	-0.2	-1.4	-0.6	-0.0	-0.1	1.2	-0.1	-0.9
Age at First Birth	1.2	1.8	9.0	1.8	-0.5	0.7	0.4	-0.3	3.0	-1.2	0.1	1.2
Bipolar Disorder (2011)	0.5	0.5	1.0	-0.8	-0.5	-0.3	-0.7	0.9	-1.0	0.8	0.5	0.0
Body Mass Index (BMI) (2010)	0.5	0.6	1.8	-0.7	-0.5	-0.8	-0.1	1.0	-1.0	0.3	0.5	-1.4
Coronary Artery Disease (CAD)	0.6	0.7	4.1	-0.3	2.0	0.5	-0.3	0.2	-0.3	-0.6	-1.2	-0.3
Crohns Disease (2012)	1.3	2.1	5.8	-2.2	2.4	0.5	-0.3	0.2	-2.4	-0.9	-0.0	-1.4
Mean Putamen Volume	1.5	1.7	6.7	-0.2	-0.1	-2.0	-0.0	0.9	0.9	-2.6	-1.6	-0.9
Fasting Glucose	0.9	1.1	3.1	1.4	0.6	-0.2	0.0	-0.8	0.9	0.6	1.6	1.8
HbA1C	0.4	0.4	1.2	-0.4	0.3	0.5	-0.3	0.9	1.1	1.1	0.3	0.1
HDL Cholesterol	0.2	0.3	0.8	0.3	-0.9	0.5	0.1	-0.0	-0.7	0.6	0.8	0.6
LDL Cholesterol	0.4	0.6	2.1	-0.1	0.5	-1.4	-0.6	-0.4	0.3	0.7	-1.4	-0.7
Lupus	0.5	0.8	3.9	-0.2	-1.1	-0.4	0.7	-0.9	0.4	2.0	-0.2	-0.6
Neuroticism (2016)	1.2	1.7	7.5	0.6	-1.9	0.2	1.1	2.7	0.1	0.4	1.4	-0.1
Primary Biliary Cirrhosis	1.7	2.5	5.8	0.8	-0.7	2.4	0.9	-2.1	-1.2	-0.9	2.1	1.8
Rheumatoid Arthritis	0.9	1.3	3.4	-0.8	1.9	0.3	1.1	-0.5	-1.7	-0.6	1.3	-1.1
Schizophrenia (2014)	0.6	1.3	5.5	-0.3	-1.6	1.0	-0.9	2.3	-0.2	-0.6	-0.0	1.0
Triglycerides	0.6	0.9	2.0	-1.3	-0.3	-0.5	-0.9	1.3	-1.4	0.3	-0.7	-1.1
Type 2 Diabetes (T2D) (2012)	0.5	0.5	1.6	-0.3	-0.3	1.3	-1.2	-0.2	-1.1	0.1	0.3	0.6
Ulcerative Colitis	1.5	2.1	6.1	-1.9	1.3	-0.3	-2.0	0.8	-2.5	0.8	-0.4	-1.6
Blood Eosinophil Count	0.1	0.9	2.7	0.3	-1.5	0.8	-0.7	-0.2	-0.8	-1.0	1.6	-0.1
Blood Platelet Count	0.1	0.6	1.8	-1.3	-1.0	0.3	0.1	-0.1	-1.0	-0.7	-0.9	0.0
Blood Red Count	0.2	2.3	9.2	0.5	-0.9	0.5	0.2	3.0	2.2	2.0	1.0	0.4
Blood White Count	0.4	2.8	7.0	-2.2	-1.1	-0.8	2.6	2.3	-0.8	-1.4	0.1	-1.8
Heel T-Score	1.3	10.7	30.7	-5.5	0.3	-2.8	-2.0	3.1	-3.7	0.7	-2.1	-5.1
BMI	0.3	1.5	4.2	-2.0	-0.8	-1.4	0.2	1.6	-0.4	0.3	-0.2	-2.0
Height	0.5	10.2	35.7	-0.6	2.6	4.0	-6.0	3.2	0.6	-4.7	0.3	-0.2
Waist Hip Ratio (WHR)	0.6	2.5	12.7	-0.2	0.2	0.5	-1.1	3.6	2.7	0.2	-0.8	0.6
Systolic Blood Pressure	0.1	0.5	1.3	-0.1	1.0	0.8	-0.4	-1.1	-0.2	-1.2	-0.1	0.3
Smoking Status	1.0	2.4	6.8	-0.6	0.0	-2.6	2.2	0.6	-1.8	0.2	-1.9	-1.5
Allergy or Eczema	0.5	1.3	2.9	1.7	1.6	-0.1	-1.5	-0.9	1.2	0.1	-0.6	1.2
Cardiovascular Disease	0.4	1.3	3.0	-1.7	0.5	-0.5	-0.0	1.1	-1.7	-1.1	-0.9	-1.3
Hypothyroidism (self reported)	0.3	0.7	1.9	0.2	0.0	1.1	1.0	1.4	-1.1	-0.5	0.2	0.9
Respiratory disease	1.8	4.1	9.9	-3.1	0.4	-3.1	-1.0	-0.8	-1.9	-0.4	-1.9	-2.8
Type 2 Diabetes (T2D) (2018)	0.6	1.0	3.1	0.7	-0.8	1.6	-0.2	1.0	0.5	-0.2	1.1	1.8
Lung FEV1/FVC ratio	0.1	0.5	1.3	1.1	-0.5	0.7	-0.5	0.3	0.4	0.9	-0.4	1.0
Lung FVC	0.4	2.0	6.2	0.1	-1.4	-1.8	1.3	-1.3	-0.2	2.5	1.4	-1.0
Neuroticism	0.6	1.4	4.0	-0.1	-0.1	-1.5	-0.9	2.0	-0.0	2.0	-1.2	-0.2
Chronotype (morning person)	0.8	1.7	5.6	2.4	0.9	0.9	1.4	0.1	2.0	-0.1	0.5	1.5
Hair Pigment	0.0	1.3	6.1	0.6	1.3	1.1	-1.0	0.7	-0.7	-2.5	-0.1	0.6
Tanning	0.0	0.4	1.3	-0.9	-0.4	-0.4	0.2	-0.7	-1.0	-0.0	0.1	-1.1
Hand grip strength (left)	0.4	1.1	6.8	-0.8	0.2	1.0	-2.6	-1.0	-0.0	-0.2	0.3	-0.4
Number of treatments/medications taken	1.4	2.4	9.8	-1.9	-0.1	-0.9	0.1	2.3	-1.2	0.2	-3.1	-1.1
Average weekly spirits intake	0.7	0.8	2.0	0.1	1.1	-1.4	1.3	0.3	0.7	-0.6	-0.9	-0.9
Sensitivity / hurt feelings	0.7	1.1	4.1	-0.8	0.4	-1.0	0.9	0.4	-1.4	2.0	0.6	-0.8
Frequency of depressed mood in last 2 weeks	2.7	3.7	10.0	-1.4	-2.7	-3.2	-0.3	-0.1	-1.6	2.5	-0.2	-2.2
Hearing difficulty/problems: Yes	0.2	0.4	1.6	-0.8	-0.1	0.4	0.4	0.1	-0.3	0.7	-1.3	-0.1
Relative age of first facial hair	1.2	2.4	11.2	-0.5	0.2	-0.5	-0.1	-3.4	-1.6	2.3	1.3	-0.4
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	4.2	-0.3	-2.0	0.0	-1.0	2.0	-0.4	1.7	-1.2	-0.2
Ever used hormone-replacement therapy (HRT)	0.8	1.1	4.6	0.0	-0.3	0.3	0.1	2.1	1.6	-1.0	-0.9	0.8
Ever had hysterectomy (womb removed)	0.4	0.4	1.5	0.1	-0.1	0.6	0.2	1.2	1.0	-0.6	0.5	0.4
Systolic blood pressure, automated reading	0.1	0.3	0.7	-0.5	0.8	-0.5	0.5	-0.8	-0.6	-0.3	0.3	-0.6
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	4.5	0.5	-1.0	0.0	-1.3	2.1	-0.3	0.7	-0.7	1.3
Angina	0.4	0.5	1.8	-0.8	-0.6	0.1	0.5	1.4	0.8	-0.5	-0.3	-0.4
Medication for hormone replacement therapy	0.4	0.4	1.8	-0.5	0.8	0.5	-0.1	1.4	0.1	-0.2	-0.7	0.3
Vitamin and mineral supplements	1.5	2.0	7.3	2.0	0.9	0.7	1.3	-1.2	2.7	-0.8	0.7	1.0
Supplements: Zinc	0.6	0.7	2.3	0.2	0.2	-1.1	-1.4	0.6	0.2	-0.1	-1.5	-0.2
Medication: Co-codamol	0.6	0.7	3.6	-0.4	0.0	-1.4	-0.8	0.5	0.2	-0.4	-1.9	-0.2
Medication: Metformin	0.4	0.6	2.3	-0.3	-1.1	0.7	0.9	1.5	-0.3	-0.5	-0.1	0.1
Diabetes (father)	1.3	1.6	5.9	0.1	-0.1	1.2	1.2	2.1	-0.6	2.4	0.2	1.0
Diabetes (mother)	0.2	0.3	0.7	0.7	-0.2	-0.1	0.8	-0.2	0.5	0.6	-0.6	0.8
Severe depression (siblings)	0.7	0.8	3.1	0.3	0.4	1.8	-0.7	-0.3	-0.6	0.9	1.3	0.7
Pack years adult smoking proportion	1.4	2.2	6.4	-1.9	-0.2	-2.5	-0.0	0.8	-1.2	-1.4	-0.1	-2.4
Impedance of leg (right)	0.3	1.5	8.7	0.1	3.0	0.5	-0.8	-1.5	-0.3	-1.3	-0.5	-0.3
Leg fat-free mass (left)	0.3	1.5	3.6	-1.8	-0.3	-0.3	-1.9	1.9	-0.5	-0.5	0.5	-1.6
Trunk fat percentage	0.4	1.7	6.8	-1.7	1.4	0.3	-0.3	2.6	-0.0	-1.2	-0.1	-1.3
Hand grip strength (right)	0.3	0.9	4.4	-0.3	1.3	1.0	-2.1	-0.9	0.3	0.6	-0.3	0.0
Townsend deprivation index at recruitment	1.7	2.3	8.2	-0.1	0.3	-2.1	0.4	2.2	-0.8	2.9	-0.4	-1.6
Current tobacco smoking	0.4	0.7	1.8	0.9	-0.2	-1.1	1.3	0.0	-0.6	1.3	0.5	-0.2
Average weekly fortified wine intake	0.7	0.8	4.0	0.8	-0.6	-0.0	0.8	-2.0	0.4	0.4	1.0	0.4
Maternal smoking around birth	0.6	0.8	2.1	0.1	-1.4	0.9	1.1	1.1	0.4	-0.2	1.1	0.9
Fed-up feelings	0.4	0.8	2.9	-0.5	0.1	-1.7	0.2	0.2	-0.7	1.7	-0.4	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.3	6.8	0.2	-1.1	-1.4	0.2	-1.0	-0.3	2.6	0.1	-0.3
Relative age voice broke	0.3	0.4	1.1	0.1	0.7	-1.0	0.3	-0.7	-0.9	0.3	0.1	-0.6
Taking other prescription medications	1.3	2.1	11.0	-1.0	-0.6	-0.3	-1.2	3.3	-0.1	-0.6	-2.1	-0.1
Age when periods started (menarche)	0.3	0.8	2.0	1.2	0.1	1.2	1.4	0.5	1.1	0.8	0.4	0.5
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	5.8	1.2	-0.1	0.3	2.4	-1.1	0.6	-0.7	0.8	1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.1	5.7	-1.5	1.4	-1.6	-1.8	1.5	-1.7	2.4	-1.2	-2.4
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.8	0.5	0.7	-0.3	-0.5	1.4	0.9	0.0	-0.3	-0.2
Qualifications: CSEs or equivalent	0.2	0.3	1.4	0.0	-0.4	0.1	0.2	0.2	-0.4	0.8	1.2	-0.2
Serious illness, injury or assault to yourself	0.4	0.5	1.1	0.9	-1.0	-0.4	1.0	-0.8	0.7	-0.4	-0.3	-0.1
High blood pressure	0.2	0.5	2.0	-0.4	-0.4	0.2	0.9	1.4	0.2	-0.5	0.8	0.1
Hayfever, allergic rhinitis or eczema	1.1	2.3	7.1	2.7	1.5	0.2	-1.2	-1.9	1.2	1.1	0.8	1.7
Multivitamins +/- minerals	2.2	2.8	7.9	-2.3	-1.6	-1.4	-1.5	1.6	-2.8	0.9	-0.6	-1.4
Stomach or abdominal pain in last month	0.8	1.0	6.6	0.2	0.8	-0.3	-0.1	0.9	0.4	0.6	-2.6	0.1
Supplements: Glucosamine	1.1	1.4	3.1	-1.0	-0.4	1.8	-1.0	1.7	-0.6	-1.3	-1.4	0.5
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.5	-0.8	-1.2	0.2	1.2	0.1	-1.2	0.2	0.7	-0.1
Medication: Atenolol	1.3	1.6	4.8	-1.1	1.3	-1.5	1.0	0.2	-0.3	-1.7	0.5	-2.2
Medication: Levothyroxine sodium	0.5	0.9	2.5	-1.2	-0.1	0.4	0.1	1.6	-1.6	0.9	-0.4	0.2
Sitting height	0.3	2.0	9.2	-0.5	-0.2	0.3	-3.0	-0.2	-0.5	-2.6	0.1	-1.3
Chronic bronchitis/emphysema (father)	1.3	1.5	6.9	-1.6	0.5	0.8	-1.4	0.4	-0.8	-2.6	0.1	-0.8
High blood pressure (mother)	0.3	0.4	2.0	-0.4	0.2	1.4	-0.2	-0.5	-0.0	0.6	-0.5	1.0
Body mass index (BMI)	0.4	1.8	9.1	-1.7	-0.5	-1.1	0.4	3.0	0.1	0.1	-0.3	-1.5
Impedance of leg (left)	0.4	1.8	9.2	0.2	3.0	0.7	-1.1	-1.7	-0.1	-1.2	-0.8	-0.1
Leg predicted mass (left)	0.3	1.5	3.6	-1.7	-0.3	-0.3	-1.9	1.9	-0.5	-0.5	0.6	-1.5
Trunk fat mass	0.5	2.2	9.9	-1.9	1.0	0.3	-0.9	3.1	0.1	-1.3	-0.4	-1.5
Waist circumference	0.8	2.8	19.7	-1.8	-0.3	-0.1	-0.6	4.4	0.6	-0.6	0.1	-1.3
Number of incorrect matches in round	0.9	1.5	4.9	-0.3	-1.3	1.0	-0.6	2.2	1.2	1.7	0.8	1.0
Past tobacco smoking	1.1	2.1	7.6	0.8	0.3	1.3	-0.6	-2.8	0.8	0.6	2.5	1.0
Alcohol usually taken with meals	0.8	1.2	6.1	-0.3	1.0	0.4	-0.7	-2.5	-1.7	-0.1	0.6	-0.0
Nervous feelings	0.4	0.7	2.2	1.5	1.2	-0.1	-0.8	-1.1	0.5	0.8	-0.1	0.5
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	7.3	0.7	-2.4	-1.1	1.3	0.5	1.8	2.7	-0.1	0.7
Hearing difficulty/problems with background noise	0.2	0.3	1.0	-1.0	0.1	-0.3	-0.1	-0.5	0.1	0.5	-0.7	-0.7
Hair/balding pattern: Pattern 2	0.5	0.6	1.9	1.0	-0.7	-0.0	-0.3	-1.4	0.5	0.9	0.3	0.7
Had menopause	0.9	1.1	3.1	-0.1	-1.6	1.2	-0.1	-0.0	0.5	-1.5	1.8	0.8
Had other major operations	1.2	1.5	4.0	1.1	-1.2	1.2	-1.5	2.0	0.7	-0.4	0.2	1.5
Forced vital capacity (FVC)	0.2	0.8	2.0	-0.3	0.7	-0.2	-1.3	-0.9	-0.6	0.6	1.4	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.5	7.4	-2.0	0.9	-2.0	-1.3	1.3	-1.9	2.6	-1.3	-2.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.4	0.3	-0.4	-0.3	1.2	-0.1	-0.7	0.8	-0.8	-0.4
Qualifications: None of the above	0.6	1.3	6.7	0.6	-0.0	-1.0	1.6	2.6	0.9	0.5	-0.4	-0.2
Financial difficulties in last 2 years	1.1	1.5	5.5	0.8	1.6	-2.3	-0.7	0.5	-0.0	0.2	-1.8	-1.0
Mouth/teeth dental problems	0.7	1.1	4.6	1.0	-0.6	1.1	1.1	-0.1	0.9	2.1	0.2	0.9
Heart attack	0.7	0.9	1.4	-1.1	1.0	-1.1	0.2	-1.0	-1.2	-0.4	0.5	-1.2
Allergy	0.5	1.3	2.5	-1.4	-1.4	0.3	1.6	1.5	-0.3	-1.3	-0.4	-0.8
Pain all over the body in last month	0.2	0.2	0.7	-0.6	0.6	-0.1	0.1	-0.1	-0.0	0.8	-0.6	0.1
Diabetes (self-reported)	0.7	1.1	3.3	0.4	-1.4	0.3	-1.0	1.8	0.9	-0.1	-0.3	1.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	3.7	1.9	1.8	-0.0	-0.7	-1.1	0.7	1.1	-0.1	1.2
Medication: Ramipril	0.3	0.4	1.2	-0.8	-0.7	-0.2	-0.1	1.1	-0.3	-0.7	0.6	-0.1
Medication: Simvastatin	1.5	2.1	5.2	1.5	-0.3	1.2	-0.7	1.7	2.3	-1.9	-0.1	1.9
Fluid intelligence score	0.4	0.7	2.8	-0.3	0.9	0.7	-1.7	-1.3	0.3	-0.2	-0.8	0.1
Illnesses of siblings	0.5	0.7	2.8	0.1	-0.2	-0.1	1.1	-1.7	-0.2	-1.1	0.8	0.2
Neuroticism score	0.4	0.8	3.8	0.8	0.8	-1.0	-0.2	0.3	0.2	2.0	-0.7	0.2
Weight	0.5	2.3	7.7	-2.3	0.3	0.1	-1.7	2.8	-0.4	-1.4	0.0	-1.8
Impedance of arm (right)	0.3	1.5	4.1	0.0	1.9	1.2	-0.4	-2.0	-1.1	-1.6	0.7	0.3
Arm fat percentage (right)	0.3	1.2	5.5	-1.6	0.0	-0.5	0.7	2.3	0.2	-0.3	0.3	-1.2
Trunk fat-free mass	0.3	2.0	7.0	-1.6	-0.3	0.4	-2.6	2.3	-0.3	-1.0	0.1	-1.2
Hip circumference	0.6	2.5	6.5	-2.3	-0.1	-0.9	-1.0	2.1	-1.0	-1.7	0.7	-2.5
Time employed in main current job	0.8	0.9	3.0	-1.3	-1.7	0.1	-0.8	0.8	0.8	1.1	-0.6	-0.5
Alcohol intake versus 10 years previously	0.3	0.5	1.2	-0.2	1.0	-0.4	-0.2	-0.9	0.6	-0.9	-1.1	-0.4
Father’s age at death	0.3	0.4	0.9	-0.3	-0.5	0.4	-0.7	-0.5	0.9	-0.2	0.9	0.5
Worrier / anxious feelings	0.1	0.3	1.2	-0.3	0.6	-0.5	0.1	-1.1	-0.4	-0.5	-0.2	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	6.9	-0.2	-0.2	-2.1	0.9	0.3	0.2	2.6	-0.3	-0.7
Falls in the last year	0.2	0.2	1.1	0.3	0.0	-1.0	-0.2	-0.4	-0.1	0.8	0.1	-0.4
Hair/balding pattern: Pattern 3	0.4	0.6	1.3	0.7	1.0	1.1	-1.1	-0.4	1.1	0.0	0.4	0.6
Number of live births	1.1	1.5	5.8	1.0	0.4	2.4	1.1	0.9	-0.2	0.6	1.5	1.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.3	0.3	0.6	0.3	-1.1	-0.6	-0.3	0.6	1.2	-0.4
Pulse rate	0.7	1.2	3.1	-1.8	-0.3	-0.5	-0.9	1.7	-0.6	-1.6	-0.5	-0.8
Happiness	0.5	0.6	2.5	0.7	-0.2	0.3	0.7	1.6	0.6	1.0	-0.0	0.4
Noisy workplace	1.3	1.6	6.5	-0.2	-0.3	-0.8	0.8	2.3	0.7	-0.6	-2.6	-0.2
Qualifications: A levels/AS levels or equivalent	0.7	1.6	8.2	0.6	0.9	0.9	-0.9	-2.9	0.2	-1.6	0.2	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.7	0.9	0.3	-0.7	0.2	-0.6	-1.3	0.4	0.4	-0.5
Mouth/teeth dental problems: Dentures	0.4	0.8	2.0	-1.4	-0.1	-1.1	-0.7	0.3	-0.7	-0.6	0.3	-1.4
Asthma	0.8	1.6	3.5	-1.7	-0.2	-1.9	-0.7	-0.0	-1.2	1.5	-0.8	-1.6
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.0	-1.4	0.8	0.5	-0.2	-0.7	-0.9	0.2	-0.5	-0.5
Medication: Cholesterol lowering	0.5	0.8	6.0	-0.2	0.3	0.6	0.3	2.4	-0.3	-0.6	-0.8	0.1
Depression (self-reported)	0.7	0.8	4.0	0.9	-1.1	-0.1	0.8	0.7	0.6	2.0	0.1	0.3
Medication: Lansoprazole	1.8	2.0	7.5	-0.7	-0.5	0.6	-1.0	2.7	1.2	0.4	-2.5	0.7
Prospective memory result	1.2	1.4	4.6	-0.5	1.5	-2.1	-0.9	1.7	0.3	-0.4	-0.9	-0.9
Lung cancer (father)	0.8	1.0	4.8	-0.1	-2.2	1.1	-0.7	0.7	0.8	-0.9	0.2	0.6
Illnesses of mother	0.3	0.3	0.9	0.5	0.4	-0.6	-0.3	-0.9	0.5	-0.7	0.2	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	3.1	0.5	1.6	0.1	-1.5	-1.0	-0.7	0.3	1.8	-0.4
Pulse wave Arterial Stiffness index	1.3	1.5	7.8	0.0	-0.1	1.4	-1.6	2.8	0.6	0.9	0.6	-0.1
Impedance of arm (left)	0.3	1.3	4.2	0.4	1.8	1.4	-0.3	-2.0	-0.8	-0.8	0.9	0.4
Arm fat mass (right)	0.4	1.5	8.4	-1.7	0.2	-0.2	-0.4	2.9	0.4	-0.6	0.2	-1.4
Trunk predicted mass	0.4	2.1	6.6	-1.7	-0.3	0.4	-2.6	2.4	-0.4	-1.1	0.2	-1.3
Standing height	0.6	5.6	22.4	-1.4	2.0	2.5	-4.7	0.3	-0.9	-3.7	0.8	-0.9
Length of working week for main job	0.9	1.0	2.2	1.3	0.4	-1.5	-0.3	1.5	1.4	-0.3	-0.7	0.6
Exposure to tobacco smoke at home	0.9	1.0	5.4	-0.2	0.4	-0.2	0.8	1.2	1.1	-0.3	-2.3	-0.3
Breastfed as a baby	0.5	0.6	2.2	0.3	-1.5	-1.2	0.7	0.2	0.2	0.9	0.1	-0.2
Tense / ‘highly strung’	0.9	1.4	5.3	0.8	-1.4	-0.6	-1.3	0.8	1.3	2.3	0.1	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	0.9	0.4	-0.1	-1.0	0.5	0.9	0.4	-0.0	-0.9	-0.5
Hair/balding pattern: Pattern 4	0.9	2.1	5.5	-2.3	1.2	-0.6	0.2	-1.1	0.2	-2.3	-1.8	-1.5
Birth weight of first child	0.4	0.7	2.2	0.0	0.2	1.4	0.7	0.4	0.3	1.0	1.5	-0.0
Peak expiratory flow (PEF)	0.5	1.2	3.5	-1.1	-0.1	1.4	-1.4	-0.0	-1.9	-1.1	0.8	-0.6
Pulse wave reflection index	1.3	1.6	9.0	-0.3	0.7	-0.6	-1.2	1.1	-0.3	3.0	0.6	-1.1
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.4	0.6	0.6	-1.0	0.3	-0.5	-0.1	1.5	0.6	-0.9
Loud music exposure frequency	1.2	1.3	2.7	-1.5	0.4	-1.6	0.5	-0.1	-1.6	1.1	-1.1	-1.3
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	4.8	1.1	0.3	1.5	-2.2	-0.9	0.4	-0.7	1.7	0.9
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	2.3	0.3	-0.0	1.5	-0.4	-1.0	-0.5	-1.1	0.5	1.2
Blood clot in the leg (DVT)	0.6	0.8	3.4	-0.8	0.3	0.4	-0.1	0.9	-1.9	0.9	-1.0	-0.5
Medication: Paracetamol	1.1	1.8	6.6	-1.2	0.9	-1.6	2.6	0.7	-1.2	0.7	-1.0	-1.1
Headache pain in last month	0.5	0.9	3.8	0.3	0.7	-1.5	0.5	0.2	-0.6	1.9	-0.8	-0.3
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	3.6	0.8	-0.5	-0.0	-0.7	-1.9	0.5	0.1	0.7	0.5
Glaucoma (self-reported)	0.7	0.8	4.0	-0.5	-1.1	-0.1	0.3	2.0	0.0	-0.1	-0.4	-1.1
Gout (self-reported)	1.1	1.4	8.9	0.6	0.3	1.4	-0.3	-0.5	-0.6	-0.5	3.0	0.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.7	-0.9	-0.4	0.9	1.4	1.3	-1.6	-0.3	0.2	0.6
Medication: Amlodipine	0.7	0.9	4.5	0.4	-0.6	-0.3	-0.6	1.7	2.1	0.2	-0.0	0.4
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.2	-0.5	-0.4	0.8	-1.5	1.0	0.2	0.9	-0.6	0.5
Birth weight	0.5	1.1	4.2	-1.1	-0.8	-1.2	-0.4	2.0	-0.3	0.2	-0.6	-1.3
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.0	-0.1	-0.7	1.0	0.6	0.9	-0.3	-0.4	1.4	0.3
High blood pressure (siblings)	0.7	1.0	3.7	-0.1	1.0	0.6	-0.4	0.8	-0.1	1.7	-1.9	0.2
Forced vital capacity (FVC), Best measure	0.3	1.2	4.0	0.0	1.2	0.0	-1.5	-1.2	-0.8	0.7	2.0	-0.7
Body fat percentage	0.4	1.7	7.6	-1.8	1.1	-0.3	0.1	2.8	0.0	-0.6	-0.5	-1.5
Leg fat percentage (right)	0.6	2.2	6.7	-2.1	0.9	-1.4	0.5	2.6	-0.0	-0.1	-1.2	-2.0
Arm fat-free mass (right)	0.4	1.8	6.7	-1.5	0.1	0.0	-2.3	2.6	-0.1	-0.6	-0.1	-1.4
Exposure to tobacco smoke outside home	1.2	1.6	7.2	-1.1	0.3	-0.0	-0.4	2.7	-0.3	-1.9	-1.5	-0.4
Comparative body size at age 10	0.4	1.1	4.2	-0.5	-2.1	-1.3	0.2	-0.6	0.1	1.0	1.4	0.4
Number of full brothers	1.4	1.8	7.8	0.1	1.0	-1.6	-1.3	2.8	-0.0	0.8	-1.2	-0.8
Worry too long after embarrassment	0.5	0.8	3.9	0.2	0.1	-0.9	-1.2	0.3	-0.2	2.0	-0.7	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	3.2	1.5	-0.0	0.9	-0.8	1.8	0.9	0.8	-0.7	1.3
Wheeze or whistling in the chest in last year	0.5	0.9	3.8	-1.0	1.3	-1.9	0.7	-0.2	-0.1	-0.3	-0.9	-0.8
Number of children fathered	0.6	0.7	2.4	0.0	0.6	-0.5	0.8	-1.2	0.6	-1.6	-0.7	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.8	-0.4	1.1	-0.2	-0.8	-0.7	1.1	-0.5	-1.3	0.3
Age at first live birth	0.5	0.9	3.0	1.1	0.0	0.3	-1.3	-1.2	1.7	-0.4	-0.1	0.8
Pulse wave peak to peak time	1.1	1.3	6.8	-0.1	0.2	-1.0	1.3	-2.6	-0.7	-1.1	-0.7	0.1
Health satisfaction	1.0	1.2	5.6	-0.3	-1.7	-0.3	-0.4	2.4	0.2	-0.4	-1.5	0.1
Shortness of breath walking on level ground	2.0	2.4	4.2	-1.3	0.9	-1.7	-1.2	1.9	0.7	-1.8	-2.0	-1.7
Qualifications: College or University degree	1.1	3.6	19.1	0.2	1.9	-0.0	-2.4	-4.4	-0.4	-1.8	-0.1	-0.2
Eye problems/disorders: None of the above	1.8	2.0	4.4	1.5	0.3	1.7	1.7	-2.1	0.6	0.9	1.1	1.9
Mouth/teeth dental problems: Loose teeth	0.7	0.8	3.8	-0.4	-0.0	0.2	-0.4	1.6	0.6	-1.9	0.6	0.3
Emphysema/chronic bronchitis	0.7	0.8	1.9	-1.3	1.4	-0.9	-0.4	-0.1	-1.2	-0.3	-0.5	-1.1
Medication for pain relief, constipation, heartburn	0.5	0.9	3.0	0.9	0.8	-0.9	-1.7	-0.9	1.0	-0.8	0.3	-0.5
Neck or shoulder pain in last month	0.8	1.1	4.1	-1.1	-0.7	-1.3	-0.1	1.0	0.0	-0.6	-2.0	-1.1
Medication: Blood pressure	0.3	0.6	3.8	-0.9	-0.1	0.3	-0.1	1.9	0.1	-0.4	-0.1	-0.3
Angina (self-reported)	0.5	0.6	2.2	-1.0	-0.7	-0.2	0.6	1.5	0.8	-0.6	-0.6	-0.6
Migraine (self-reported)	1.2	1.5	5.0	1.1	-1.7	1.1	-0.4	-0.4	0.4	2.2	0.4	1.6
Medication: Ibuprofen	0.5	0.6	2.1	-1.5	0.6	0.3	-0.6	-0.8	-1.1	0.3	-0.4	-0.7
Medication: Allopurinol	1.0	1.3	4.1	0.1	-0.0	1.3	0.3	1.6	0.1	-1.9	2.0	0.1
Medication: Omeprazole	1.0	1.2	5.5	0.3	-1.2	-1.1	-0.0	0.3	1.6	-0.2	-2.3	-0.3
Medication: Seretide 50 evohaler	0.2	0.3	0.7	-0.7	-0.4	0.3	0.3	-0.1	-0.4	0.3	0.9	-0.7
Mean time to correctly identify matches	0.4	0.8	1.9	-0.1	-0.9	0.4	1.4	-0.1	-1.4	0.4	1.3	0.4
Heart disease (mother)	1.2	1.4	5.6	-0.2	0.3	0.8	-2.2	0.9	0.0	-2.4	0.6	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	1.4	1.1	-0.7	1.1	1.1	0.8	0.7	-0.3	-0.4	1.2
Whole body fat mass	0.5	2.3	10.3	-2.2	0.8	-0.2	-0.4	3.2	-0.0	-1.0	-0.6	-1.8
Leg fat mass (right)	0.6	2.4	9.0	-2.3	0.6	-1.1	-0.2	3.0	-0.1	-0.4	-0.8	-2.2
Arm predicted mass (right)	0.4	2.0	6.8	-1.8	0.1	-0.1	-2.0	2.6	-0.3	-1.0	-0.3	-1.6
Pulse rate, automated reading	0.5	1.5	3.7	-1.9	-1.1	-0.6	-0.5	1.9	-1.4	-0.7	0.3	-1.4
Alcohol intake frequency.	0.4	0.9	3.1	1.6	0.4	-1.0	-0.8	-0.0	1.8	-0.2	0.7	0.4
Comparative height size at age 10	0.6	3.5	14.8	-1.0	1.1	1.8	-3.9	1.2	0.6	-3.0	-0.3	-0.5
Number of full sisters	0.9	1.0	4.3	0.5	-0.9	-0.0	1.0	-0.1	-1.5	2.1	0.8	0.4
Suffer from ‘nerves’	0.7	1.1	5.2	0.1	-0.3	-0.8	-0.1	1.6	0.8	2.3	-1.1	-0.1
Overall health rating	1.8	3.8	18.5	0.6	-1.1	0.3	-0.7	4.3	2.7	-0.1	-2.3	1.1
Chest pain or discomfort	1.0	1.5	5.5	-0.7	1.3	-0.5	-0.9	2.4	-0.0	0.5	-1.5	-1.3
Had major operations	0.7	0.9	5.1	-0.9	-2.3	-0.2	0.6	-0.1	0.1	0.8	0.6	-0.8
Age at last live birth	0.7	1.0	2.5	1.6	0.8	0.4	-0.9	-1.1	1.6	-0.8	-0.2	0.6
Family relationship satisfaction	1.4	1.7	5.9	0.6	-2.4	0.2	1.5	1.8	-0.9	0.8	1.4	-0.1
Leg pain on walking	1.1	1.4	3.5	-0.3	0.7	-1.5	-1.3	1.9	0.5	0.4	-1.6	-1.3
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.6	1.6	0.6	0.0	1.6	-0.9	0.3	-0.1	0.0	0.9
Commuting to job workplace: Car/motor vehicle	1.0	1.2	3.1	0.5	0.0	1.3	1.3	0.6	0.8	-1.8	-0.5	1.6
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	4.5	-0.1	-1.1	1.4	1.1	-0.2	0.3	0.2	2.1	1.3
Medication: Aspirin	0.6	0.8	3.5	-0.6	-0.9	1.1	0.3	-0.2	-1.9	-0.1	1.1	0.5
Supplements: Vitamin C	0.6	0.7	2.1	-0.8	-0.8	0.9	-0.5	0.8	-1.4	0.3	-0.9	0.7
Knee pain experienced in last month	0.5	0.7	2.1	-0.3	0.9	-0.3	0.0	1.5	0.9	-0.6	-1.4	-0.1
Hypertension (Self-reported)	0.2	0.6	4.0	-0.7	-0.3	0.1	0.6	2.0	-0.0	-0.7	0.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.5	0.5	-1.4	-0.0	1.4	-0.2	1.9	0.5	-1.9	0.4
Illnesses of father: Heart disease	0.3	0.3	1.4	-0.2	1.2	-0.5	-0.1	-0.4	-0.2	1.1	-0.0	-0.1
Illnesses of siblings: Diabetes	1.0	1.2	4.1	-1.0	-0.3	-1.6	-0.6	1.2	0.2	-0.6	-2.0	-1.1
Smoking status: Previous	0.9	1.3	5.4	0.1	-0.5	-0.5	-0.4	2.3	-0.3	-0.2	-2.3	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	3.7	-0.7	1.4	-0.7	-1.7	-1.9	-1.9	-1.1	1.4	-1.7
Whole body fat-free mass	0.3	1.9	6.0	-1.7	-0.4	0.0	-2.5	2.3	-0.4	-0.7	0.2	-1.4
Leg fat-free mass (right)	0.2	1.3	4.2	-1.6	-0.5	0.1	-2.1	1.6	-0.5	-0.4	0.5	-1.2
Arm fat percentage (left)	0.3	1.2	5.9	-1.5	0.3	-0.5	0.7	2.4	0.2	-0.1	0.2	-1.2
Average weekly red wine intake	0.5	0.8	3.1	0.1	-1.2	0.8	1.1	0.1	-0.5	1.8	0.8	0.1
Handedness (chirality/laterality): Left-handed	1.0	1.2	3.6	0.1	-1.5	-1.6	0.9	1.9	-0.9	0.0	-0.6	-0.7
Mood swings	0.5	0.9	1.4	1.1	0.9	-1.2	1.1	0.4	0.9	1.2	-1.0	0.4
Loneliness, isolation	0.5	0.7	1.6	1.1	-0.3	0.1	-0.8	0.0	0.6	1.0	1.3	1.2
Long-standing illness, disability or infirmity	1.9	3.0	10.9	-0.6	-1.6	0.3	1.3	3.3	1.5	-1.0	-2.7	0.5
Ever had bowel cancer screening	0.5	0.6	1.8	0.1	1.4	0.4	0.9	0.7	0.7	-1.2	-0.6	0.1
Diabetes diagnosed by doctor	0.5	0.8	3.9	-0.0	-0.9	-0.0	-0.4	2.0	0.5	0.3	-1.1	1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	3.8	-0.8	0.4	0.2	0.8	-0.2	-2.0	-1.8	0.9	-0.4
Friendships satisfaction	0.4	0.5	1.5	0.4	0.2	0.6	0.7	1.0	-0.7	-0.1	1.2	-0.7
Qualifications: nursing, teaching	0.7	1.0	4.0	-1.2	0.5	2.0	-0.6	-1.1	-0.2	-1.3	-0.1	0.1
Commuting to job workplace: Walk	0.4	0.4	1.6	-0.1	0.9	-0.2	0.6	-0.7	0.6	-1.3	0.1	-0.6
Eye problems/disorders: Cataract	0.7	0.8	2.7	-0.2	-1.0	-1.7	0.8	0.7	0.0	0.2	-1.2	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.6	-0.4	0.5	-1.3	-0.3	0.2	-0.9	-0.5	-1.1	-0.6
Medication for cholesterol	0.3	0.4	0.8	-0.4	0.2	-0.1	0.6	-0.9	-0.6	0.8	0.7	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	8.6	-0.3	0.7	-1.1	-0.2	0.6	0.7	0.0	-2.9	-0.7
Back pain experienced in last month	1.3	2.0	8.4	-1.2	-2.4	1.0	0.3	2.9	-0.1	-0.6	-0.6	-0.1
Mineral and other dietary supplements	1.4	1.8	5.9	1.9	0.8	0.9	-0.3	-0.7	1.0	2.4	1.3	1.5
Breast cancer (self-reported)	0.7	0.9	1.6	-0.2	-0.2	-1.2	1.3	-1.1	-1.0	-0.9	0.9	-1.0
Asthma (self-reported)	1.0	2.0	4.7	-1.9	0.2	-2.2	-0.8	-0.1	-1.4	1.4	-1.0	-1.9
Osteoporosis (self-reported)	1.1	1.4	5.9	0.7	-1.4	2.4	0.1	-0.2	1.1	-0.9	0.2	1.3
Osteoarthritis (self-reported)	0.8	1.0	4.4	-0.1	-0.3	-0.9	0.8	2.1	0.4	-0.8	-1.5	-0.4
Medication: Aspirin	0.5	0.7	2.8	-0.5	-1.3	0.8	0.2	0.3	-1.7	0.3	0.7	0.4
Medication: Gliclazide	1.6	1.8	3.2	-1.7	-1.5	-0.6	0.9	1.5	-1.8	1.4	-1.0	-1.2
Illnesses of father: None of the above (group 1)	0.5	0.6	1.2	0.9	-0.8	0.9	0.3	0.1	0.7	-0.9	-0.9	1.1
Smoking status: Current	0.7	1.1	3.5	0.0	-0.0	-1.9	1.8	-0.3	-1.0	0.8	-0.1	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.6	3.3	8.1	0.2	0.4	-2.8	0.8	-2.9	-1.2	2.2	2.2	-1.3
Whole body water mass	0.3	1.9	5.8	-1.7	-0.4	0.2	-2.4	2.4	-0.3	-0.9	0.3	-1.3
Leg predicted mass (right)	0.2	1.3	4.3	-1.6	-0.5	0.1	-2.1	1.6	-0.4	-0.4	0.4	-1.2
Arm fat mass (left)	0.4	1.8	10.6	-1.7	0.3	-0.2	-0.1	3.2	0.4	-0.6	0.2	-1.4
Number of self-reported non-cancer illnesses	1.4	2.5	12.4	-1.5	-0.5	0.1	0.2	3.5	-0.1	-0.5	-2.6	-0.3
Average weekly champagne plus white wine intake	0.8	1.1	2.4	-1.5	0.5	-1.1	-0.0	-0.3	-0.8	-1.3	-1.1	-1.6
Miserableness	0.2	0.4	1.3	0.4	0.5	-0.1	1.1	-0.6	-0.7	0.9	0.0	0.4
Guilty feelings	0.6	1.0	4.6	0.3	0.0	0.7	0.2	2.2	0.2	1.5	-0.5	0.9
Wears glasses or contact lenses	0.6	0.7	2.0	-0.1	-1.1	1.3	-0.6	-0.1	-0.4	-0.3	1.4	0.5
Ever taken oral contraceptive pill	0.7	0.8	2.5	-0.5	0.9	-1.0	-0.3	1.0	0.8	0.7	-1.6	-0.7
Hearing aid user	1.4	1.6	3.9	-0.1	-0.5	0.7	1.9	-0.3	1.2	1.4	-2.0	1.7
Mother’s age at death	0.4	0.5	2.3	0.0	-1.0	-0.3	1.5	-1.1	0.3	0.3	0.0	-0.3
Financial situation satisfaction	0.3	0.4	1.4	-0.0	0.2	-0.1	1.2	-0.2	-0.6	1.0	-0.8	-0.1
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.3	0.4	-1.5	0.4	0.7	-1.4	1.0	-1.1	0.4	1.1
Commuting to job workplace: Public transport	0.7	0.8	4.2	0.7	1.3	-0.1	-0.7	-0.0	-0.2	2.1	0.3	0.2
Eye problems/disorders: Glaucoma	1.2	1.4	4.2	-1.5	-1.1	-1.0	-0.1	1.8	-0.8	0.1	-0.2	-2.0
Medication: Blood pressure	0.3	0.5	1.5	0.5	-0.7	0.5	0.6	0.5	0.8	-1.2	0.4	0.6
Pain type(s) experienced in last month: Hip pain	1.8	2.3	5.9	-2.4	-1.4	-0.3	-1.0	0.1	-0.9	-2.4	-1.6	-1.6
Supplements: Fish oil (including cod liver oil)	1.3	1.7	5.0	-1.6	-0.9	-0.8	0.3	-0.5	-1.8	-2.2	-0.3	-1.6
High cholesterol (Self-reported)	1.0	1.8	7.4	1.1	1.1	0.7	-0.5	1.5	1.5	-2.7	-0.5	0.9
Medication: Bendroflumethiazide	0.4	0.5	1.5	-0.5	-0.7	-0.2	0.7	-0.2	-1.1	-1.2	0.4	-0.8
Medication: Paracetamol	0.9	1.4	5.4	-0.8	0.7	-1.3	2.3	-0.0	-1.1	0.8	-1.1	-0.9
Medication: Lisinopril	0.1	0.2	0.8	-0.1	-0.3	-0.0	-0.6	0.0	0.6	-0.9	-0.2	-0.1
Medication: Atorvastatin	0.2	0.3	1.0	-0.4	0.4	0.2	0.2	1.0	-0.9	-0.1	0.6	-0.4
Illnesses of father: High blood pressure	0.5	0.6	2.9	0.3	1.0	0.1	0.1	0.7	-1.0	1.7	0.5	-0.0
Alcohol drinker status: Never	1.4	1.7	7.2	1.1	-1.3	-1.4	0.6	0.9	1.3	2.7	0.0	0.3
Ever smoked	1.1	1.9	3.5	-1.7	0.8	-1.2	0.7	1.4	-1.9	-0.5	-1.9	-1.5
Basal metabolic rate	0.3	1.9	5.8	-1.8	-0.1	0.2	-2.3	2.4	-0.3	-1.0	0.2	-1.4
Leg fat percentage (left)	0.5	1.8	6.4	-1.9	0.9	-0.9	0.2	2.5	0.2	0.0	-1.4	-1.6
Arm fat-free mass (left)	0.4	2.1	6.9	-1.9	-0.1	0.1	-2.1	2.6	-0.3	-1.2	0.1	-1.4
Number of operations (self-reported)	1.1	1.7	3.2	0.5	-1.8	1.6	-1.1	1.8	1.5	1.1	-0.0	1.1
Average weekly beer plus cider intake	0.3	0.4	1.7	-0.2	0.6	-0.4	1.0	1.3	-0.1	-0.4	-0.5	-0.5
Irritability	0.5	0.8	1.8	1.1	-0.2	0.8	-0.5	-0.7	1.0	1.3	-0.1	1.3
Risk taking	0.3	0.4	1.0	-0.7	-0.5	-0.8	-0.6	1.0	0.3	-0.6	-0.7	-0.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.8	0.4	0.6	0.7	0.8	-0.1	0.1	-1.7	-0.5	0.9
Fractured/broken bones in last 5 years	0.8	1.1	4.4	0.6	-1.1	0.6	1.0	0.8	0.7	2.1	-0.4	1.0
Age started oral contraceptive pill	0.6	0.7	2.7	-0.4	0.9	-0.0	-0.2	-1.2	0.4	-1.6	-1.1	0.3
Diastolic blood pressure, automated reading	0.7	2.1	5.8	-1.6	1.3	-1.9	1.3	-0.1	-1.1	1.4	-0.4	-2.4
Ever depressed for a whole week	0.5	0.6	2.2	0.3	-0.7	-0.9	1.5	-0.7	-1.0	0.7	-0.2	-0.5
Unable to work because of sickness or disability	0.8	1.1	3.9	-1.5	0.0	-0.2	-1.2	2.0	-0.7	-0.2	-0.6	-1.0
Commuting to job workplace: Cycle	1.2	1.5	4.2	-0.8	2.1	-1.0	-1.0	-1.3	-1.1	-0.1	-0.4	-1.9
Myopia	0.7	1.1	2.5	1.3	1.2	-1.0	1.0	-1.6	0.4	0.9	0.8	-0.5
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.7	0.4	-0.2	0.0	-1.3	-1.2	-0.2	0.4	-0.3	0.2
Cholesterol lowering medication	1.0	1.4	3.4	1.8	0.0	1.1	-0.8	1.1	1.5	-0.8	0.9	1.6
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	9.0	-0.2	-1.4	-0.9	-0.8	0.9	1.4	-0.4	-3.0	-0.2
Pain experienced in last month	2.0	3.3	10.6	1.9	1.6	1.9	0.1	-3.3	-0.0	-0.6	2.6	1.3
Supplements: Calcium	0.8	0.9	2.3	0.2	0.5	-0.8	-1.5	0.5	1.3	-1.0	-1.3	-0.4
Basal cell carcinoma (self-reported)	0.4	0.5	2.1	0.6	-1.4	-0.3	0.2	-0.9	0.8	0.8	-0.1	0.4
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.3	-1.1	1.0	-1.0	-0.0	-1.1	-1.1	-0.2	0.4	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.6	-0.8	0.1	0.5	-0.3	0.8	-1.6	0.9	-0.7	-0.5
Heart disease (siblings)	0.6	0.7	1.8	0.9	-0.7	-0.3	-1.1	1.3	0.5	0.2	1.4	0.2
Alcohol drinker status: Previous	2.3	2.7	8.6	2.9	1.4	1.4	1.0	0.4	1.5	1.0	-0.0	2.7
Pack years of smoking	1.3	1.8	4.2	-1.9	-0.5	-2.1	0.1	1.2	-1.0	-1.3	0.2	-2.0
Impedance of whole body	0.4	1.8	7.3	0.5	2.7	1.3	-0.6	-2.1	-0.3	-1.3	-0.0	0.4
Leg fat mass (left)	0.6	2.4	9.7	-2.3	0.7	-0.9	-0.5	3.1	0.1	-0.5	-1.0	-2.1
Arm predicted mass (left)	0.5	2.3	8.5	-1.9	-0.2	0.3	-2.1	2.9	-0.3	-1.4	0.1	-1.4