Hub : Genes

STRADB

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Coronary 0.2920 0.1200 0.0057 0.028 NA 0.007 NA 0.090 4.0e-02 NA 1.7e-01 NA 5.8e-04
2 GTEx Cells Transformed fibroblasts 0.0670 0.0320 0.0034 0.022 NA 0.005 NA 0.018 7.7e-03 NA 1.4e-01 NA 1.4e-02
3 GTEx Esophagus Muscularis 0.0880 0.0410 0.0062 -0.004 NA -0.005 NA -0.004 6.3e-01 NA 9.9e-01 NA 7.9e-01
4 GTEx Nerve Tibial 0.1056 0.0501 0.0037 0.032 NA 0.007 NA 0.017 2.3e-03 NA 9.1e-02 NA 2.1e-02
5 GTEx Whole Blood 0.0770 0.0340 0.0034 0.042 NA 0.013 NA 0.024 8.5e-05 NA 2.1e-02 NA 2.5e-03
6 YFS Blood 0.0977 0.0187 0.0000 0.167 0.158 0.170 0.168 0.171 3.5e-52 3.4e-49 3.3e-53 1.9e-52 1.5e-53
7 TCGA Kidney Renal Clear Cell Carcinoma 0.0302 0.0259 0.0089 0.011 0.014 0.007 NA 0.007 1.8e-02 8.3e-03 4.6e-02 NA 4.9e-02
8 TCGA Prostate Adenocarcinoma 0.0300 0.0234 0.0033 0.016 0.012 0.008 NA 0.010 7.0e-03 1.8e-02 4.7e-02 NA 3.0e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.7 2.7 -1.6 1.3 0.1 0.4 0.5 0.6 -0.6 -0.4
Bipolar Disorder or Schizophrenia 0.3 0.8 1.8 -1.4 1.2 -0.7 0.3 1.1 0.6 -0.5 -0.7
Depressed Affect (Nagel 2018) 1.1 2.3 4.7 -0.7 1.4 -2.1 2.1 -0.2 -1.3 2.2 0.7
Depression (Nagel 2018) 1.2 1.8 5.6 -2.4 2.1 -0.9 1.6 0.2 -0.5 0.9 0.3
Intelligence (Savage-Jansen 2018) 0.4 1.1 2.7 1.1 0.4 0.5 0.9 -1.1 -1.6 1.3 0.9
Neuroticism (Nagel 2018) 0.6 1.4 3.2 -0.9 0.9 -0.9 1.8 -0.4 -1.3 1.8 0.6
Schizophrenia (2018) 0.2 0.4 1.2 -0.4 0.5 -1.0 0.0 1.1 0.3 -0.2 -0.5
Schizophrenia vs Biploar Disorder 0.6 0.8 2.3 0.7 0.6 -1.5 0.4 0.3 -0.9 1.2 0.8
Worry (Nagel 2018) 0.3 0.7 4.6 -0.3 -2.2 -0.3 -0.2 0.5 0.4 -0.0 -0.7
Alzheimer’s Disease (in mother) 1.7 2.0 3.3 1.2 -1.7 -1.0 -1.4 1.8 1.2 -0.9 -1.7
Alzheimer’s Disease (in father) 0.5 0.5 1.2 -0.3 -1.1 -0.4 -0.7 0.1 0.9 -0.8 -0.8
Alzheimer’s Disease (including proxy) 1.6 2.3 4.3 0.6 -2.1 -1.0 -1.8 1.2 1.6 -1.6 -1.6
Crohns Disease (2017) 0.3 0.7 3.0 0.8 0.5 0.1 0.5 -1.7 -0.4 -0.3 1.2
Irritable Bowel Disease (IBD) 0.2 0.4 1.2 0.9 -0.1 -0.6 -0.1 -0.8 0.7 -1.1 0.3
Ulcerative Colitis (UC) 0.3 0.5 1.6 0.5 -0.3 -0.6 -0.4 0.3 1.3 -1.0 -0.5
Major Depression (MDD) 0.9 1.1 3.1 -1.8 1.2 -0.7 0.9 -0.7 -0.8 1.2 0.4
Reaction Time 0.1 0.2 0.6 0.1 0.1 -0.7 0.2 0.8 0.3 -0.1 0.2
Verbal and Numeric Reasoning (VNR) 0.3 0.8 3.5 1.9 -1.5 0.2 -0.8 -0.0 0.2 -0.1 -0.4
Breast Cancer 4.5 10.8 57.0 2.1 -7.5 -1.2 -3.8 -0.9 1.6 -1.5 -1.9
Ovarian Cancer 1.2 1.6 4.0 -2.0 -1.6 1.1 0.7 -1.4 -1.0 1.3 0.5
Prostate Cancer 2.1 3.0 7.3 2.2 -2.7 -0.4 -2.0 1.2 1.6 -1.1 -1.6
Age at First Birth 1.9 2.8 4.7 -1.7 1.9 0.2 1.9 -1.1 -1.7 1.8 2.2
Bipolar Disorder (2011) 0.4 0.4 1.2 -1.1 -0.5 0.3 -0.2 0.6 0.9 -0.7 -0.3
Body Mass Index (BMI) (2010) 0.8 1.1 2.7 0.3 -0.7 -1.2 -0.9 0.8 1.3 -1.0 -1.7
Coronary Artery Disease (CAD) 0.8 1.0 2.8 0.8 0.2 -1.7 0.5 -1.0 -0.9 0.9 1.2
Crohns Disease (2012) 0.8 1.3 3.6 1.9 -0.6 -1.9 -0.1 -1.3 -0.5 0.3 1.0
Mean Putamen Volume 1.4 1.6 3.8 0.7 -1.5 1.3 -1.2 0.7 1.2 -1.0 -1.9
Fasting Glucose 0.7 0.8 1.6 1.2 0.3 -0.5 -1.2 0.1 0.9 -1.2 -1.0
HbA1C 1.4 1.5 3.3 1.4 -1.6 -1.1 -0.3 0.9 1.4 -1.8 -0.8
HDL Cholesterol 1.3 2.1 3.6 -1.6 1.1 -0.1 1.8 -1.0 -1.6 1.6 1.9
LDL Cholesterol 2.4 3.8 6.6 0.3 -1.2 -2.1 -2.1 1.6 2.4 -2.6 -2.3
Lupus 1.1 1.6 4.2 -0.9 0.5 1.3 2.1 -0.7 -1.6 1.2 1.2
Neuroticism (2016) 0.6 0.8 2.5 0.4 1.2 -1.6 0.3 0.0 -0.6 1.4 0.4
Primary Biliary Cirrhosis 0.9 1.3 7.3 -2.7 0.3 1.3 0.1 0.6 -0.0 0.5 -0.6
Rheumatoid Arthritis 1.1 1.5 4.7 -0.6 0.3 0.1 1.5 -2.2 -0.8 -0.5 2.0
Schizophrenia (2014) 0.6 1.4 2.3 -0.5 1.5 -1.5 -0.4 1.3 1.1 -1.2 -1.2
Triglycerides 2.7 4.4 7.2 2.3 -2.7 -1.8 -2.7 0.9 1.8 -1.8 -2.2
Type 2 Diabetes (T2D) (2012) 0.7 0.8 2.1 1.0 0.3 -0.2 0.9 -0.5 -0.8 1.4 1.4
Ulcerative Colitis 0.4 0.6 1.8 0.5 0.2 -1.0 -0.3 0.3 1.3 -1.1 -0.1
Blood Eosinophil Count 0.2 1.3 6.5 -0.8 -1.1 -2.5 0.2 -0.4 -0.3 1.1 -0.7
Blood Platelet Count 3.9 45.5 92.0 2.1 -9.6 -3.7 -7.8 7.4 7.4 -5.3 -7.4
Blood Red Count 1.2 11.2 16.6 1.8 3.3 3.6 3.0 -3.8 -4.1 3.0 3.7
Blood White Count 2.9 21.5 37.2 6.1 -5.6 -4.7 -5.9 2.4 3.8 -3.7 -3.7
Heel T-Score 0.1 0.6 2.7 -1.6 0.0 0.7 -0.6 0.6 0.0 0.5 -0.7
BMI 0.2 0.9 2.6 -1.0 1.6 -1.6 -0.3 -1.0 0.1 -0.1 -0.6
Height 0.1 1.6 4.0 -1.1 -0.0 -0.7 1.8 1.2 -1.1 1.0 2.0
Waist Hip Ratio (WHR) 0.6 2.5 6.6 -2.6 2.4 1.1 1.9 -0.5 -0.9 0.6 1.3
Systolic Blood Pressure 0.1 0.5 1.0 1.0 -0.4 1.0 -0.3 -0.7 -0.2 -0.0 0.9
Smoking Status 0.6 1.4 5.8 -1.1 1.6 -2.4 0.6 0.8 0.5 0.1 -0.8
Allergy or Eczema 1.5 3.9 10.3 -2.4 1.5 -0.5 3.2 -1.6 -1.7 1.6 2.1
Cardiovascular Disease 0.3 0.9 2.6 1.4 -1.6 0.7 -1.1 -0.4 0.3 -0.2 -0.7
Hypothyroidism (self reported) 0.1 0.3 0.7 -0.8 -0.6 -0.7 0.2 -0.6 0.6 -0.7 0.3
Respiratory disease 0.8 1.8 6.7 1.8 -1.6 -2.6 -1.3 0.6 0.1 -0.2 0.3
Type 2 Diabetes (T2D) (2018) 0.3 0.7 2.2 -0.9 0.6 -1.5 -0.3 -0.0 0.8 -0.9 -0.4
Lung FEV1/FVC ratio 0.2 0.9 4.3 -1.2 2.1 0.6 0.9 -0.1 0.1 0.2 -0.3
Lung FVC 0.2 0.9 3.3 0.4 1.8 1.1 0.1 1.0 0.2 -0.6 -0.9
Neuroticism 0.4 0.9 3.6 -0.2 -0.3 -1.9 0.2 1.3 0.5 0.5 -1.0
Chronotype (morning person) 3.0 6.9 9.7 0.0 -2.6 -1.9 -3.1 2.8 3.1 -3.1 -2.9
Hair Pigment 0.1 2.0 7.1 -2.4 2.7 -1.1 1.3 -0.1 -0.4 0.5 0.4
Tanning 0.1 0.6 1.3 0.6 0.8 -0.8 0.6 -1.1 -0.9 0.7 0.8
Hand grip strength (left) 0.3 0.7 2.0 -1.4 1.2 -1.0 1.0 -0.0 0.5 -0.6 -0.1
Number of treatments/medications taken 0.7 1.2 4.8 1.6 -1.1 -2.2 -0.7 -0.5 0.1 0.3 0.0
Average weekly spirits intake 0.3 0.4 1.4 -0.6 -0.7 0.0 0.4 -0.3 -1.2 1.0 0.2
Sensitivity / hurt feelings 0.2 0.4 1.3 0.5 -0.1 -0.1 0.5 -0.2 -1.0 1.1 -0.0
Frequency of depressed mood in last 2 weeks 0.5 0.7 1.7 -1.1 -0.2 0.1 1.3 -0.1 -0.8 1.3 0.8
Hearing difficulty/problems: Yes 0.4 0.7 1.6 1.2 -0.8 0.1 -0.6 -0.8 0.7 -1.2 -0.3
Relative age of first facial hair 0.5 1.1 5.5 -1.0 0.0 0.9 0.0 2.3 0.4 0.6 -0.9
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 2.2 -0.6 1.5 0.5 0.3 -0.3 0.5 -0.5 0.3
Ever used hormone-replacement therapy (HRT) 1.2 1.5 3.6 1.9 -0.1 0.7 0.5 -1.4 -1.6 1.4 1.1
Ever had hysterectomy (womb removed) 0.8 0.9 2.0 0.2 0.1 -1.3 0.7 -0.7 -1.4 1.3 1.0
Systolic blood pressure, automated reading 0.1 0.3 0.6 0.8 -0.2 0.8 -0.0 -0.4 -0.5 0.6 0.2
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 4.4 -1.3 0.3 2.1 0.3 0.4 -0.3 0.5 -0.2
Angina 2.1 2.8 5.7 0.7 -1.7 -0.0 -1.9 1.6 2.4 -2.2 -1.4
Medication for hormone replacement therapy 3.0 3.4 8.0 0.3 0.3 0.1 2.1 -1.4 -2.4 2.8 2.5
Vitamin and mineral supplements 0.5 0.6 1.4 0.1 -0.3 0.3 -0.9 1.2 1.1 -0.7 -1.0
Supplements: Zinc 0.5 0.5 1.4 -1.2 -0.2 -0.8 0.9 -0.3 -0.5 0.1 1.1
Medication: Co-codamol 0.7 0.9 1.8 0.8 1.4 0.9 0.9 -0.6 -0.8 0.8 1.1
Medication: Metformin 0.5 0.7 3.1 -0.8 0.9 -1.8 -0.2 0.4 0.4 -0.5 -0.3
Diabetes (father) 0.5 0.6 1.6 -0.6 -0.8 1.3 -0.7 0.8 0.6 -0.8 -0.6
Diabetes (mother) 0.1 0.1 0.7 -0.0 -0.0 -0.1 -0.0 -0.8 -0.1 0.1 0.3
Severe depression (siblings) 1.4 1.5 2.6 -0.5 1.2 1.6 1.3 -1.6 -1.3 1.2 0.7
Pack years adult smoking proportion 0.1 0.2 0.7 0.4 -0.3 -0.8 -0.1 -0.2 0.4 -0.6 -0.0
Impedance of leg (right) 0.1 0.4 1.1 0.9 -0.6 0.3 -0.6 1.0 0.4 -0.2 -0.4
Leg fat-free mass (left) 0.3 1.6 3.2 -1.8 1.7 -0.7 1.6 -1.1 -1.0 0.7 1.1
Trunk fat percentage 0.1 0.4 1.5 0.1 0.7 -1.2 -0.2 -1.0 -0.4 0.5 -0.3
Hand grip strength (right) 0.4 1.0 2.6 -1.6 0.4 -0.4 -0.1 0.5 1.3 -1.6 -1.0
Townsend deprivation index at recruitment 0.7 1.0 1.8 -1.4 0.7 -0.9 1.1 -0.6 -0.9 1.0 1.2
Current tobacco smoking 0.6 0.9 2.8 -1.3 1.7 -0.7 0.9 1.0 -0.2 0.9 -0.1
Average weekly fortified wine intake 1.1 1.3 3.1 0.2 -0.5 0.5 0.5 -1.7 -1.8 1.7 0.6
Maternal smoking around birth 0.2 0.3 0.8 -0.9 0.8 0.0 0.4 -0.2 0.5 -0.5 -0.5
Fed-up feelings 0.5 0.8 2.4 -0.2 0.4 -1.6 1.3 -0.3 -0.6 1.2 0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 1.0 2.4 -1.3 1.6 -0.5 1.5 0.2 -0.5 0.7 0.6
Relative age voice broke 0.3 0.5 1.3 0.2 0.5 1.2 0.5 0.4 -0.7 1.0 0.6
Taking other prescription medications 1.6 2.4 14.5 1.0 0.5 -3.8 0.2 -1.3 -0.7 0.4 1.0
Age when periods started (menarche) 0.3 0.8 3.1 0.0 -1.8 -0.7 0.6 -0.9 -0.4 -0.1 1.1
Bilateral oophorectomy (both ovaries removed) 0.9 1.1 3.2 0.0 1.8 1.1 0.8 -0.9 -1.1 1.1 0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 4.3 2.1 -0.1 1.6 -0.7 -0.4 -0.3 0.4 -0.2
Tinnitus: Yes, but not now, but have in the past 0.9 1.0 2.2 -1.0 0.6 1.5 1.3 -0.0 -0.6 1.3 0.8
Qualifications: CSEs or equivalent 2.6 3.4 8.6 -0.5 2.9 0.9 2.2 -2.1 -1.8 1.6 1.6
Serious illness, injury or assault to yourself 0.7 0.9 4.0 -0.6 2.0 -0.8 0.9 -0.6 -0.3 -0.2 0.8
High blood pressure 0.1 0.3 2.1 -0.1 0.1 -0.2 0.0 -1.4 -0.6 0.5 0.0
Hayfever, allergic rhinitis or eczema 2.3 4.9 11.0 -2.1 2.4 -0.0 3.3 -1.9 -2.2 2.1 2.3
Multivitamins +/- minerals 0.6 0.7 1.7 0.8 -1.3 -0.5 -1.0 0.3 0.8 -0.9 -0.9
Stomach or abdominal pain in last month 0.2 0.2 0.9 0.2 -0.1 -0.5 0.2 -0.7 -0.3 0.9 0.2
Supplements: Glucosamine 0.5 0.7 3.4 0.4 -1.8 -1.1 -0.1 -0.4 -0.4 0.0 0.6
Diverticular disease/diverticulitis (self-reported) 0.8 1.0 2.0 -0.7 1.3 1.4 0.9 -1.0 -0.9 0.9 0.7
Medication: Atenolol 0.1 0.1 0.4 0.5 -0.3 -0.6 0.1 0.4 0.1 0.0 -0.1
Medication: Levothyroxine sodium 0.3 0.4 1.1 0.5 0.6 -1.1 0.9 -1.0 -0.3 0.4 0.2
Sitting height 0.1 0.6 2.3 -0.9 -1.5 -0.4 0.1 0.8 0.1 -0.5 0.5
Chronic bronchitis/emphysema (father) 0.2 0.3 0.9 -0.6 -0.7 -0.4 -0.3 -1.0 0.1 0.1 0.1
High blood pressure (mother) 0.4 0.5 1.9 -1.1 1.4 -0.7 0.2 -0.2 0.2 -0.6 -0.1
Body mass index (BMI) 0.2 1.0 4.0 -1.1 1.4 -2.0 -0.2 -0.6 0.1 0.1 -0.9
Impedance of leg (left) 0.0 0.2 0.4 0.6 -0.6 0.5 -0.1 0.5 -0.0 0.1 0.4
Leg predicted mass (left) 0.3 1.7 3.1 -1.8 1.7 -0.7 1.6 -1.2 -1.1 0.7 1.2
Trunk fat mass 0.2 0.7 2.2 -0.7 1.2 -1.5 0.3 -1.0 -0.5 0.5 -0.1
Waist circumference 0.4 1.3 3.8 -1.9 1.7 -1.7 0.7 -0.6 -0.3 0.4 -0.2
Number of incorrect matches in round 0.2 0.3 0.7 -0.6 0.1 -0.2 -0.1 0.6 0.7 -0.1 -0.8
Past tobacco smoking 0.7 1.4 7.5 0.4 0.5 2.7 0.3 -0.5 -0.7 -0.2 1.5
Alcohol usually taken with meals 0.6 0.9 1.7 0.2 0.8 1.2 0.6 -1.1 -1.3 1.2 0.8
Nervous feelings 0.6 1.1 2.9 0.2 -1.1 1.3 1.2 -0.3 -1.1 1.7 0.4
Frequency of tenseness / restlessness in last 2 weeks 1.4 2.1 4.3 -0.7 0.4 -1.0 1.8 -1.2 -1.7 2.1 1.9
Hearing difficulty/problems with background noise 0.2 0.3 0.5 -0.4 0.7 -0.5 0.3 -0.7 -0.4 -0.1 0.7
Hair/balding pattern: Pattern 2 1.5 1.9 4.7 -2.2 1.3 1.0 1.5 -1.0 -1.1 0.8 1.6
Had menopause 0.5 0.6 1.7 -0.2 -0.4 -0.5 0.8 -0.4 -1.0 0.8 1.3
Had other major operations 0.6 0.7 3.6 0.4 1.9 -0.1 1.1 0.1 -0.0 -0.3 0.7
Forced vital capacity (FVC) 0.2 1.0 4.2 0.1 1.3 2.0 0.9 -0.3 -0.6 -0.1 0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 4.5 2.1 -0.7 1.5 -0.9 -0.7 -0.3 0.2 -0.2
Ever unenthusiastic/disinterested for a whole week 0.2 0.2 0.7 -0.5 0.6 0.5 0.8 -0.1 -0.1 0.5 0.2
Qualifications: None of the above 0.3 0.5 2.0 0.1 -0.5 -1.4 -1.0 0.4 0.6 -0.6 0.0
Financial difficulties in last 2 years 0.8 1.1 4.2 -1.0 2.0 -1.5 0.8 0.5 -0.0 0.3 -0.4
Mouth/teeth dental problems 1.7 2.6 5.2 -0.8 1.0 2.1 1.8 -2.3 -1.4 0.8 1.7
Heart attack 0.3 0.4 1.2 -0.4 0.7 -0.5 0.1 0.4 0.9 -1.1 -0.2
Allergy 0.6 1.3 3.4 1.0 -0.7 0.7 -1.9 0.8 1.1 -1.2 -1.2
Pain all over the body in last month 0.3 0.4 0.9 -0.8 0.2 -0.4 -0.4 -0.9 0.4 -0.9 -0.4
Diabetes (self-reported) 0.8 1.3 2.7 -1.6 0.9 -1.6 -0.5 1.0 1.1 -0.6 -1.2
Hayfever/allergic rhinitis (self-reported) 0.6 0.7 1.5 -0.8 -0.1 -0.3 1.1 -0.4 -0.9 1.2 1.2
Medication: Ramipril 0.5 0.7 2.4 1.5 -0.1 -1.1 -0.4 -0.8 0.4 -0.8 0.2
Medication: Simvastatin 2.1 3.1 4.6 0.7 -2.0 -1.3 -2.1 1.8 2.0 -1.7 -1.9
Fluid intelligence score 0.4 0.7 2.5 1.1 -1.2 -1.6 -0.2 -0.5 -0.5 0.5 0.2
Illnesses of siblings 1.1 1.5 4.4 -2.1 2.1 -0.7 1.5 0.4 -0.4 0.6 0.1
Neuroticism score 0.3 0.5 1.4 1.2 -0.8 -0.6 0.3 0.4 -0.3 1.2 -0.1
Weight 0.2 0.9 2.3 -1.5 1.2 -1.5 0.7 -0.7 -0.4 0.4 0.2
Impedance of arm (right) 0.4 1.8 6.7 2.6 -1.2 2.0 -0.3 -0.1 -0.7 0.9 0.6
Arm fat percentage (right) 0.1 0.5 1.5 0.0 1.2 -1.2 -0.4 -0.6 -0.1 0.4 -0.9
Trunk fat-free mass 0.4 2.4 7.4 -2.7 2.1 -1.0 2.0 -0.4 -0.8 0.4 1.1
Hip circumference 0.2 0.8 4.2 -0.6 0.2 -2.0 0.1 -1.0 -0.6 0.7 -0.0
Time employed in main current job 0.6 0.7 3.0 -0.6 1.0 1.7 0.1 0.4 0.3 -0.6 0.4
Alcohol intake versus 10 years previously 0.7 1.1 2.7 0.2 -0.2 -0.3 -1.4 0.6 1.4 -1.6 -1.2
Father’s age at death 0.9 1.2 2.8 -1.7 -1.1 1.0 -0.1 1.6 0.5 0.5 -1.2
Worrier / anxious feelings 0.7 1.3 3.0 0.3 -1.7 -1.2 -1.1 0.6 1.2 -1.5 -0.8
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.7 2.9 0.2 0.7 -1.7 1.5 -1.5 -1.4 1.4 1.3
Falls in the last year 0.3 0.5 1.2 0.3 0.9 0.4 -0.6 0.3 0.9 -0.3 -1.1
Hair/balding pattern: Pattern 3 0.4 0.5 2.4 1.6 -0.0 -0.9 -0.7 0.2 0.1 0.3 -0.6
Number of live births 0.8 1.2 1.8 -0.8 -0.3 -1.2 -1.0 1.4 1.2 -1.3 -1.3
Forced expiratory volume in 1-second (FEV1) 0.4 1.4 5.2 -0.2 2.0 2.3 1.0 -0.7 -0.5 -0.4 0.5
Pulse rate 1.5 2.5 6.2 -0.7 1.3 -0.0 2.5 -1.7 -1.9 1.9 1.3
Happiness 0.3 0.4 1.1 -1.1 -0.1 -0.8 0.5 -0.6 0.1 -0.2 0.9
Noisy workplace 1.1 1.4 5.2 2.3 -0.5 -1.7 0.1 -0.7 -0.9 0.8 0.9
Qualifications: A levels/AS levels or equivalent 0.4 0.9 3.7 -1.9 -0.4 0.6 1.2 0.7 -0.1 0.7 0.3
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.2 5.9 0.4 0.6 2.4 1.1 -0.9 -0.4 0.4 0.7
Mouth/teeth dental problems: Dentures 3.6 6.1 11.5 1.7 -2.7 -0.9 -3.0 3.4 2.7 -2.0 -2.4
Asthma 1.2 2.4 10.7 2.2 -1.1 -3.3 -0.4 -0.1 -0.7 0.9 0.9
Medication: Ibuprofen (e.g. Nurofen) 0.7 0.9 2.2 -0.2 0.1 -0.3 1.1 -1.5 -0.8 1.3 1.0
Medication: Cholesterol lowering 4.7 7.3 12.5 0.5 -1.5 -2.3 -2.8 3.3 3.5 -2.8 -3.5
Depression (self-reported) 0.2 0.2 0.9 -0.4 0.7 -0.9 0.1 -0.2 0.5 -0.2 -0.2
Medication: Lansoprazole 0.9 1.0 4.7 0.3 0.8 -1.5 0.2 -2.2 -0.5 -0.3 0.4
Prospective memory result 1.1 1.3 3.1 0.3 -0.4 -0.5 -1.5 1.1 1.8 -1.6 -1.0
Lung cancer (father) 0.4 0.5 1.8 0.2 1.1 -0.4 -0.4 -0.2 0.7 -1.3 -0.5
Illnesses of mother 0.6 0.7 2.4 0.8 0.8 -0.7 0.6 -0.2 -1.0 1.5 0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 2.6 -1.0 1.6 1.6 0.8 -0.3 -0.2 -0.5 0.5
Pulse wave Arterial Stiffness index 0.1 0.1 0.5 -0.3 -0.3 -0.7 0.4 -0.0 0.1 0.2 -0.2
Impedance of arm (left) 0.4 2.0 8.1 2.9 -1.4 1.5 -0.1 -0.6 -1.0 1.1 1.0
Arm fat mass (right) 0.3 1.1 4.1 -0.9 1.3 -2.0 0.4 -0.8 -0.5 0.8 -0.2
Trunk predicted mass 0.4 2.3 6.9 -2.6 2.0 -1.1 2.0 -0.5 -0.8 0.5 1.1
Standing height 0.2 2.3 6.9 -1.4 0.1 0.9 2.3 -0.7 -1.5 0.8 2.6
Length of working week for main job 1.4 1.6 4.8 0.2 -0.4 0.9 -1.4 0.7 1.9 -2.2 -0.9
Exposure to tobacco smoke at home 0.5 0.6 2.5 -0.1 1.6 -0.1 -0.1 0.9 0.8 -0.9 -0.0
Breastfed as a baby 0.3 0.4 1.4 0.5 1.2 -0.0 -0.0 -0.9 -0.2 -0.6 0.4
Tense / ‘highly strung’ 0.5 0.8 2.7 0.6 -1.6 0.4 0.7 -0.9 -0.6 1.2 0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 1.2 -0.1 1.0 -1.1 0.8 0.5 0.4 0.2 -0.6
Hair/balding pattern: Pattern 4 0.4 0.9 4.2 -0.6 -2.0 -1.3 -0.2 0.1 -0.2 0.7 0.4
Birth weight of first child 0.6 1.1 3.7 0.4 -0.8 -0.0 -0.9 1.9 1.3 -1.1 -0.7
Peak expiratory flow (PEF) 1.0 2.4 4.4 -1.0 2.0 1.6 1.7 -2.1 -1.5 0.5 1.5
Pulse wave reflection index 1.5 1.8 3.7 1.6 -0.6 -0.3 -1.9 0.9 1.5 -1.5 -1.5
Ever highly irritable/argumentative for 2 days 1.3 1.6 6.2 -0.1 1.1 2.5 1.1 1.4 -0.3 1.3 -0.7
Loud music exposure frequency 0.5 0.5 1.9 1.3 0.7 -1.4 -0.0 -0.3 -0.0 -0.2 -0.0
Qualifications: O levels/GCSEs or equivalent 0.7 1.1 3.0 -0.5 -0.4 0.8 -0.4 1.5 1.3 -0.8 -1.7
Mouth/teeth dental problems: Bleeding gums 1.3 1.7 3.2 0.3 1.8 -0.7 1.0 -1.8 -1.6 0.8 1.6
Blood clot in the leg (DVT) 2.7 3.5 9.4 1.7 -3.1 0.7 -2.2 1.3 1.6 -1.8 -1.7
Medication: Paracetamol 0.2 0.3 0.6 0.4 -0.2 -0.6 -0.2 0.5 0.8 -0.3 -0.8
Headache pain in last month 0.7 1.2 5.4 0.0 -0.7 -2.3 -0.7 0.6 1.0 -0.4 -1.4
Medication for cholesterol, blood pressure or diabetes 1.9 3.2 5.3 0.4 1.5 1.5 1.9 -2.3 -2.2 1.5 2.3
Glaucoma (self-reported) 0.3 0.4 1.1 1.0 -0.4 0.9 0.2 -0.7 -0.5 0.5 -0.1
Gout (self-reported) 0.1 0.1 0.5 -0.7 0.3 -0.4 0.0 0.3 0.1 0.1 -0.2
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 1.6 -0.1 0.1 -1.3 0.6 -0.7 -0.3 0.5 0.5
Medication: Amlodipine 0.0 0.1 0.3 -0.3 -0.1 0.2 0.1 -0.3 0.0 -0.0 -0.6
Medication: Ventolin 100micrograms inhaler 1.0 1.3 2.7 1.6 -1.0 -1.6 -0.0 -0.8 -0.8 1.0 1.2
Birth weight 0.4 0.9 2.0 -0.6 0.8 1.1 1.1 -1.1 -0.7 -0.1 1.4
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.3 -1.2 -0.9 0.2 -0.5 0.6 0.8 -0.8 -0.5
High blood pressure (siblings) 1.0 1.4 4.4 2.0 -1.1 0.9 -0.6 -2.1 -0.4 -0.1 0.7
Forced vital capacity (FVC), Best measure 0.1 0.4 1.7 -0.3 0.7 1.3 0.3 0.3 0.0 -0.6 0.3
Body fat percentage 0.1 0.5 2.0 0.1 0.8 -1.4 -0.4 -0.6 -0.2 0.5 -0.7
Leg fat percentage (right) 0.2 0.9 2.8 -0.5 1.2 -1.7 -0.6 -0.0 0.2 0.3 -1.4
Arm fat-free mass (right) 0.3 1.8 6.8 -2.6 1.4 -1.4 1.5 -0.4 -0.4 0.1 0.8
Exposure to tobacco smoke outside home 0.7 1.0 5.4 0.9 -0.1 -2.3 -0.6 0.5 0.6 -0.6 0.1
Comparative body size at age 10 0.3 0.8 2.3 1.2 -0.4 -0.3 -1.1 0.8 0.8 -0.2 -1.5
Number of full brothers 1.3 1.6 3.4 -1.6 1.4 -0.3 1.3 -1.9 -1.2 0.8 1.1
Worry too long after embarrassment 0.2 0.3 0.6 0.2 0.7 0.6 0.5 -0.5 -0.8 0.5 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 3.1 -0.9 1.1 0.2 1.8 -1.2 -0.9 1.4 1.1
Wheeze or whistling in the chest in last year 0.5 0.8 4.0 2.0 0.1 -1.4 -0.5 -0.6 -0.1 -0.3 0.2
Number of children fathered 0.4 0.5 1.4 -0.2 -0.3 0.5 -0.6 0.6 1.0 -1.2 -0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.3 -1.1 -0.2 -0.4 -0.3 0.3 0.9 -1.1 -0.8
Age at first live birth 2.0 3.5 8.5 -1.1 1.1 1.4 2.9 -1.6 -2.0 2.0 2.1
Pulse wave peak to peak time 0.1 0.1 0.3 0.2 0.5 0.5 -0.3 0.3 0.1 -0.4 0.1
Health satisfaction 0.4 0.5 1.7 -1.3 1.0 0.1 0.8 -0.6 -0.3 0.6 -0.3
Shortness of breath walking on level ground 1.0 1.1 3.0 -0.3 1.2 1.7 1.3 -0.5 -0.7 1.1 1.0
Qualifications: College or University degree 0.8 2.4 6.6 0.2 -0.9 1.2 1.2 -2.6 -1.9 1.6 1.7
Eye problems/disorders: None of the above 0.8 0.9 3.1 -1.8 1.3 -0.0 1.2 -0.6 -0.4 0.6 0.1
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.5 -0.3 -0.3 -0.5 -0.4 1.1 1.2 -0.5 -0.9
Emphysema/chronic bronchitis 1.3 1.4 9.0 -3.0 0.1 1.1 0.9 0.2 -0.2 0.1 0.5
Medication for pain relief, constipation, heartburn 0.5 0.8 2.5 -1.2 -0.5 1.6 -0.1 1.1 0.6 -0.7 -0.3
Neck or shoulder pain in last month 0.8 1.2 2.4 0.3 -0.5 -1.5 -1.1 1.6 1.1 -0.3 -1.4
Medication: Blood pressure 0.5 0.9 3.9 -0.9 -0.1 -2.0 -0.2 1.1 0.6 0.1 -0.9
Angina (self-reported) 2.0 2.6 5.3 0.8 -1.6 -0.3 -1.9 1.5 2.3 -2.1 -1.3
Migraine (self-reported) 0.6 0.8 1.5 0.2 0.2 -0.4 0.9 -1.2 -1.2 1.2 0.9
Medication: Ibuprofen 1.5 1.8 3.9 0.3 0.1 0.2 1.4 -2.0 -1.6 1.9 1.5
Medication: Allopurinol 0.2 0.3 1.1 -0.7 0.3 -1.1 -0.2 -0.5 -0.1 -0.0 0.2
Medication: Omeprazole 1.6 1.9 3.5 0.7 1.1 -0.8 1.1 -1.8 -1.9 1.7 1.4
Medication: Seretide 50 evohaler 0.4 0.5 1.7 1.3 0.9 -0.7 -0.0 0.6 -0.3 0.5 0.0
Mean time to correctly identify matches 0.4 0.7 1.4 0.3 -0.6 -0.5 -0.9 1.2 1.0 -0.9 -0.7
Heart disease (mother) 0.5 0.6 2.3 1.5 -1.2 0.2 -0.5 -0.4 -0.0 -0.8 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.5 1.8 5.7 0.0 0.4 2.4 1.0 -1.9 -1.0 0.5 1.7
Whole body fat mass 0.2 0.9 3.1 -0.6 1.4 -1.8 0.4 -0.9 -0.6 0.7 -0.1
Leg fat mass (right) 0.3 1.0 4.2 -1.0 1.4 -2.0 -0.0 -0.4 -0.1 0.5 -0.7
Arm predicted mass (right) 0.3 1.7 6.1 -2.5 1.5 -1.3 1.6 -0.5 -0.5 0.2 0.9
Pulse rate, automated reading 1.3 4.3 9.1 -0.3 1.5 -0.8 2.4 -2.2 -3.0 2.8 2.0
Alcohol intake frequency. 1.3 3.0 4.8 1.3 -2.1 1.1 -2.2 2.1 1.8 -1.3 -1.3
Comparative height size at age 10 0.1 0.4 1.1 -0.8 -0.3 1.1 0.8 0.3 -0.4 -0.1 0.7
Number of full sisters 0.1 0.2 0.6 -0.0 0.7 0.3 -0.2 -0.8 0.1 -0.3 0.1
Suffer from ‘nerves’ 0.3 0.4 2.0 0.5 -1.4 0.7 0.3 -0.7 -0.2 0.1 0.5
Overall health rating 0.6 1.3 8.3 0.3 0.5 -2.9 -0.4 -1.1 0.1 -0.6 -0.0
Chest pain or discomfort 0.5 0.7 3.9 1.2 -0.4 -2.0 -0.2 0.1 -0.1 0.5 0.1
Had major operations 0.4 0.4 1.1 -1.1 1.0 0.3 0.6 -0.7 -0.4 0.2 0.6
Age at last live birth 1.6 2.3 5.2 -1.5 1.2 -0.2 2.3 -1.3 -1.6 1.6 1.8
Family relationship satisfaction 1.0 1.2 5.0 -1.4 1.2 -2.2 0.1 -0.3 0.0 -0.7 1.0
Leg pain on walking 1.0 1.3 4.6 -0.0 -0.3 1.3 -0.3 2.1 1.4 -0.5 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 1.5 -0.8 0.9 -0.4 0.8 -0.8 -1.1 1.2 0.3
Commuting to job workplace: Car/motor vehicle 1.9 2.2 4.7 0.3 -0.3 -2.2 -1.2 1.5 1.9 -1.9 -1.4
Illness, injury, bereavement, stress in last 2 years 2.2 2.7 5.5 0.4 -2.2 0.2 -2.3 1.5 1.7 -1.6 -1.6
Medication: Aspirin 0.9 1.2 3.5 -0.9 0.8 -1.9 -0.9 0.7 1.0 -1.2 -0.9
Supplements: Vitamin C 1.0 1.1 2.9 0.7 -0.2 0.4 1.2 -1.1 -1.3 1.1 1.7
Knee pain experienced in last month 2.0 3.2 4.9 1.5 -1.6 -0.4 -2.1 2.2 2.1 -1.5 -2.2
Hypertension (Self-reported) 0.1 0.2 1.1 -0.3 -0.4 -0.1 -0.3 -1.0 -0.4 0.4 -0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 2.4 0.2 1.0 0.5 0.1 -1.5 -0.1 -0.8 0.1
Illnesses of father: Heart disease 0.2 0.3 0.8 0.3 0.5 0.9 -0.4 0.3 0.2 -0.9 -0.2
Illnesses of siblings: Diabetes 1.0 1.3 2.6 1.1 -0.5 -0.5 -1.6 1.0 1.3 -1.2 -1.4
Smoking status: Previous 0.6 0.9 3.8 0.4 -0.9 -2.0 -0.5 -0.4 0.6 -0.4 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.3 1.4 -0.2 -0.6 0.4 0.3 -0.3 0.5 -1.2 0.4
Whole body fat-free mass 0.4 2.1 6.1 -2.5 1.9 -0.8 1.9 -0.7 -0.9 0.5 1.2
Leg fat-free mass (right) 0.4 1.9 3.7 -1.9 1.6 -0.4 1.8 -1.3 -1.2 0.8 1.5
Arm fat percentage (left) 0.2 0.7 2.2 -0.0 1.2 -1.5 -0.2 -0.8 -0.3 0.6 -0.6
Average weekly red wine intake 0.3 0.5 1.1 0.2 0.7 0.5 0.7 -1.0 -1.0 0.5 0.4
Handedness (chirality/laterality): Left-handed 0.7 0.9 1.6 0.5 -1.2 1.1 -0.7 0.8 1.1 -1.3 -0.4
Mood swings 0.2 0.3 1.1 0.5 0.2 -1.1 0.5 0.5 0.2 0.5 -0.3
Loneliness, isolation 1.9 2.6 4.3 2.1 0.5 -1.3 1.7 -1.4 -1.7 1.7 2.0
Long-standing illness, disability or infirmity 0.2 0.3 0.9 0.8 0.9 -1.0 0.2 -0.3 0.0 0.3 -0.0
Ever had bowel cancer screening 1.0 1.2 4.8 0.3 -2.2 -0.7 -1.4 0.7 0.4 0.2 -1.1
Diabetes diagnosed by doctor 0.6 1.0 1.4 -1.1 0.7 -1.1 -0.6 0.7 1.2 -1.1 -1.1
Ever had stillbirth, spontaneous miscarriage or termination 2.3 2.5 5.2 0.7 -0.7 -1.2 -1.6 2.3 2.0 -1.6 -1.6
Friendships satisfaction 1.4 1.8 6.3 -1.1 1.1 -2.5 1.1 -0.8 -1.1 0.8 1.4
Qualifications: nursing, teaching 0.3 0.5 1.7 0.0 0.4 0.4 -0.2 1.3 0.9 -0.4 -0.9
Commuting to job workplace: Walk 3.4 3.6 7.8 -0.6 0.8 0.9 2.1 -2.2 -2.7 2.8 1.6
Eye problems/disorders: Cataract 3.4 4.0 10.0 3.2 -1.5 0.2 -2.6 2.0 1.7 -1.7 -1.5
Mouth/teeth dental problems: Mouth ulcers 1.0 1.6 4.3 2.1 -0.8 -0.8 -1.5 1.5 0.9 -0.2 -1.3
Medication for cholesterol 0.9 1.4 4.4 -2.0 2.1 -0.4 1.3 -0.0 -0.6 0.8 0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 3.1 -0.6 0.4 -0.6 1.4 -0.8 -1.4 1.8 0.8
Back pain experienced in last month 0.7 1.0 2.2 0.8 0.7 -0.4 0.7 -1.3 -1.1 1.5 1.2
Mineral and other dietary supplements 0.2 0.3 0.7 0.8 0.5 -0.4 -0.2 0.4 -0.2 0.8 -0.5
Breast cancer (self-reported) 1.6 1.9 8.9 -1.6 3.0 -0.2 1.7 0.3 -0.4 0.4 0.4
Asthma (self-reported) 1.4 2.8 12.5 2.4 -1.4 -3.5 -0.7 0.1 -0.5 0.8 0.7
Osteoporosis (self-reported) 0.4 0.5 2.4 -0.3 -0.3 0.5 0.8 -0.4 -0.6 0.5 1.6
Osteoarthritis (self-reported) 2.0 2.6 7.7 2.8 -1.9 0.4 -2.1 1.2 1.0 -0.8 -1.4
Medication: Aspirin 1.0 1.2 3.0 -0.7 0.3 -1.7 -1.1 0.8 1.2 -1.2 -1.2
Medication: Gliclazide 0.4 0.5 2.7 -0.7 1.6 0.1 0.4 -0.5 0.1 -0.5 -0.0
Illnesses of father: None of the above (group 1) 0.2 0.3 1.0 -0.4 0.3 -0.0 0.6 0.8 -0.3 1.0 -0.4
Smoking status: Current 0.6 0.9 2.1 -1.2 1.5 -1.0 0.5 1.4 0.2 0.6 -0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 1.7 0.3 0.0 1.3 0.5 -0.6 -1.0 0.5 0.3
Whole body water mass 0.4 2.2 6.1 -2.5 1.9 -0.9 1.9 -0.7 -0.9 0.6 1.2
Leg predicted mass (right) 0.4 2.1 4.3 -2.1 1.6 -0.4 1.9 -1.3 -1.2 0.8 1.5
Arm fat mass (left) 0.3 1.1 4.0 -0.9 1.4 -2.0 0.4 -1.0 -0.5 0.7 -0.2
Number of self-reported non-cancer illnesses 0.7 1.2 5.5 0.9 -1.0 -2.4 -0.4 -1.0 -0.5 0.7 -0.1
Average weekly champagne plus white wine intake 0.3 0.5 1.3 1.1 -0.6 1.1 -0.4 -0.7 -0.2 0.3 0.2
Miserableness 0.3 0.5 1.3 0.1 1.1 -0.4 0.7 0.7 -0.2 1.1 -0.3
Guilty feelings 1.4 2.2 4.8 0.6 0.7 1.2 1.7 -1.1 -1.9 2.2 1.5
Wears glasses or contact lenses 0.3 0.3 1.5 0.2 -0.7 -1.2 -0.4 -0.0 -0.4 0.5 0.3
Ever taken oral contraceptive pill 0.6 0.7 1.7 0.8 -0.2 1.0 -0.5 0.0 0.8 -1.1 -1.3
Hearing aid user 3.0 3.4 6.9 0.7 -0.7 0.7 -1.9 2.6 2.2 -2.3 -2.1
Mother’s age at death 0.9 1.1 3.4 -1.7 -0.8 1.9 0.5 0.4 -0.4 1.2 0.0
Financial situation satisfaction 1.6 2.0 7.2 -1.2 2.7 -0.6 1.8 -1.1 -0.9 0.4 1.2
Tinnitus: Yes, now most or all of the time 0.3 0.3 2.2 -1.5 0.3 -0.5 0.1 -0.1 0.1 0.5 -0.0
Commuting to job workplace: Public transport 4.2 5.0 8.1 -0.0 2.0 2.3 2.9 -1.9 -2.8 2.5 2.1
Eye problems/disorders: Glaucoma 0.3 0.4 1.0 0.4 -0.2 0.8 0.0 1.0 0.7 -0.5 -0.8
Medication: Blood pressure 0.6 1.1 4.4 1.1 -1.2 0.6 -0.1 -2.1 -0.8 -0.1 0.9
Pain type(s) experienced in last month: Hip pain 0.3 0.4 1.1 -1.0 -0.2 -0.9 -0.0 0.3 0.5 -0.2 -0.9
Supplements: Fish oil (including cod liver oil) 0.6 0.8 2.6 -0.4 -0.8 0.9 -0.8 0.6 1.1 -1.6 -0.5
High cholesterol (Self-reported) 2.6 4.6 8.7 1.5 -2.1 -1.0 -3.0 1.9 2.4 -2.5 -2.2
Medication: Bendroflumethiazide 1.6 2.4 7.4 0.3 -2.1 -2.7 -1.6 0.8 1.1 -0.8 -1.4
Medication: Paracetamol 0.4 0.5 1.2 0.5 -1.1 -0.1 -0.5 0.7 1.0 -0.5 -0.9
Medication: Lisinopril 1.0 1.3 6.1 -2.5 0.9 -1.2 0.1 0.5 0.8 -1.0 -0.4
Medication: Atorvastatin 2.4 2.9 6.2 1.0 -0.2 -0.5 -2.2 1.6 2.2 -2.5 -1.8
Illnesses of father: High blood pressure 0.8 1.0 2.9 1.7 -0.5 -0.8 -0.2 -1.4 -0.8 0.1 1.1
Alcohol drinker status: Never 4.8 5.8 14.3 -0.1 -2.1 -0.3 -2.6 3.8 2.9 -2.1 -2.8
Ever smoked 0.5 0.9 3.0 -1.1 0.3 -1.7 0.9 0.1 -0.4 1.2 -0.4
Basal metabolic rate 0.3 1.9 5.2 -2.3 1.9 -1.1 1.6 -0.8 -0.8 0.5 1.0
Leg fat percentage (left) 0.2 0.8 2.7 -0.7 1.2 -1.6 -0.4 -0.3 0.2 0.2 -1.1
Arm fat-free mass (left) 0.3 1.5 4.8 -2.2 1.4 -1.6 1.3 -0.4 -0.5 0.2 0.7
Number of operations (self-reported) 0.3 0.4 2.6 -0.2 1.6 -0.6 0.1 0.0 0.3 -0.7 -0.1
Average weekly beer plus cider intake 0.1 0.1 0.2 -0.4 -0.3 -0.2 0.4 -0.0 0.2 -0.2 0.5
Irritability 0.2 0.3 0.7 -0.7 0.5 -0.1 0.7 0.2 -0.1 0.8 -0.5
Risk taking 0.4 0.6 2.5 -0.9 1.6 0.4 0.9 -0.4 -0.3 0.5 0.1
Ever had prostate specific antigen (PSA) test 0.5 0.6 2.1 1.5 -1.1 -0.3 -1.0 0.1 0.1 0.1 -0.7
Fractured/broken bones in last 5 years 0.9 1.2 3.2 -1.8 0.8 0.6 0.2 -1.3 0.3 -1.6 0.8
Age started oral contraceptive pill 0.5 0.7 2.4 0.5 -1.6 1.1 -1.1 -0.1 0.3 -0.3 -0.5
Diastolic blood pressure, automated reading 0.2 0.5 1.6 -0.3 0.8 1.3 0.3 -0.9 -0.6 0.6 0.2
Ever depressed for a whole week 0.4 0.4 1.2 -1.1 0.4 1.1 0.8 -0.2 -0.3 0.2 0.4
Unable to work because of sickness or disability 0.2 0.3 1.2 0.3 0.0 0.3 -0.4 -0.1 0.7 -1.1 0.4
Commuting to job workplace: Cycle 0.4 0.4 1.5 -0.6 -0.8 1.2 0.0 -0.7 -0.4 0.3 0.5
Myopia 0.1 0.2 0.7 -0.2 -0.1 0.8 -0.8 -0.5 -0.2 -0.1 0.2
Vascular/heart problems diagnosed by doctor 0.1 0.3 1.8 -0.2 0.2 0.2 -0.0 1.3 0.5 -0.4 -0.2
Cholesterol lowering medication 1.9 2.8 4.9 2.2 -2.0 0.3 -2.0 0.5 1.9 -2.2 -1.0
Medication: Omeprazole (e.g. Zanprol) 1.2 1.4 3.4 0.6 0.8 -0.7 0.8 -1.8 -1.6 1.4 1.1
Pain experienced in last month 0.4 0.6 3.1 -0.3 0.5 1.8 0.3 0.2 0.0 -0.6 0.9
Supplements: Calcium 1.1 1.3 4.5 -0.5 -0.1 -1.6 -0.2 0.6 1.5 -2.1 0.2
Basal cell carcinoma (self-reported) 15.5 18.5 57.8 -2.6 7.6 -0.8 4.9 -3.3 -4.5 4.2 3.1
Heart attack/myocardial infarction (self-reported) 0.2 0.3 1.0 -0.6 0.8 -0.2 0.2 0.1 0.6 -1.0 -0.0
Deep venous thrombosis (DVT) (self-reported) 2.3 2.9 7.7 1.7 -2.8 0.8 -2.0 1.0 1.5 -1.6 -1.6
Heart disease (siblings) 0.6 0.7 2.2 1.5 -1.3 -0.8 -1.1 -0.4 -0.4 0.2 -0.1
Alcohol drinker status: Previous 0.2 0.2 0.5 -0.4 -0.7 0.7 0.3 -0.6 0.2 0.1 0.3
Pack years of smoking 0.3 0.4 0.8 0.9 -0.9 -0.9 -0.4 0.1 0.6 -0.7 -0.3
Impedance of whole body 0.2 1.2 5.3 2.3 -1.6 1.1 -0.6 -0.0 -0.3 0.3 0.5
Leg fat mass (left) 0.3 1.2 4.4 -1.3 1.6 -2.1 0.2 -0.5 -0.1 0.5 -0.5
Arm predicted mass (left) 0.2 1.3 4.7 -2.2 1.3 -1.4 1.1 -0.3 -0.2 -0.1 0.5