TWAS hub - STUB1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0398	0.0147	0.00026	0.036	0.026	0.029	0.027	0.030	3.1e-06	7.1e-05	0.00003	4.7e-05	1.9e-05
2	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2300	0.0890	0.00450	-0.003	-0.005	-0.004	NA	-0.004	5.0e-01	8.8e-01	0.64000	NA	6.6e-01
3	TCGA	Ovarian Serous Cystadenocarcinoma	0.0450	0.0270	0.00280	0.036	0.036	0.024	NA	0.021	1.8e-03	1.8e-03	0.00950	NA	1.3e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Height	8.8	170.4	309.8	14.1	1.7	17.6
Smoking Status	8.7	20.9	33.2	-5.8	-1.2	-5.3
Average weekly champagne plus white wine intake	8.7	12.0	18.7	4.3	-1.3	4.0
Standing height	8.4	83.8	151.3	10.0	-0.4	12.3
Ever smoked	8.0	14.0	22.7	-4.3	-0.9	-4.8
Comparative height size at age 10	7.6	41.9	78.7	6.8	-0.6	8.9
Sitting height	7.3	51.5	90.8	8.0	0.2	9.5
Past tobacco smoking	7.0	12.8	22.6	3.8	1.0	4.8
Smoking status: Previous	6.2	9.2	17.3	-3.0	-1.2	-4.2
Happiness	6.0	7.3	11.3	3.1	0.8	3.4
Loud music exposure frequency	5.6	6.1	10.7	-2.8	-0.2	-3.3
Qualifications: None of the above	5.5	11.7	17.6	-4.2	0.4	-4.2
Alcohol intake frequency.	5.4	12.6	20.3	-4.2	-0.0	-4.5
Trunk predicted mass	5.1	29.2	47.7	6.3	-0.6	6.9
Trunk fat-free mass	4.9	28.1	46.2	6.1	-0.6	6.8
Number of incorrect matches in round	4.8	8.1	13.3	3.3	0.1	3.6
Whole body fat-free mass	4.8	27.2	43.3	6.1	-1.1	6.6
Alcohol intake versus 10 years previously	4.7	7.0	11.1	-3.3	-1.5	-2.8
Age at first live birth	4.7	8.4	13.3	3.7	0.2	3.4
Age at First Birth	4.5	6.6	9.8	3.0	-0.9	3.1
Qualifications: College or University degree	4.5	14.2	22.9	4.8	1.3	4.2
Leg fat-free mass (right)	4.4	23.5	35.4	5.7	-1.4	6.0
Whole body water mass	4.4	25.2	39.9	5.9	-1.0	6.3
Leg predicted mass (right)	4.2	22.7	34.0	5.7	-1.4	5.8
Leg fat-free mass (left)	4.0	21.4	32.1	5.5	-1.2	5.7
Current tobacco smoking	4.0	6.5	12.1	-3.5	-1.1	-2.5
Leg predicted mass (left)	4.0	21.2	31.7	5.5	-1.2	5.6
Arm predicted mass (right)	4.0	20.4	32.7	5.3	-0.8	5.7
Medication: Blood pressure	3.9	7.4	12.1	3.5	-0.0	3.2
Basal metabolic rate	3.9	21.5	33.8	5.5	-0.9	5.8
Pain experienced in last month	3.9	6.6	9.4	2.5	1.9	3.1
Pulse wave Arterial Stiffness index	3.8	4.4	6.9	1.4	-2.6	2.1
Osteoarthritis (self-reported)	3.8	5.0	7.2	-2.7	1.1	-2.5
Arm fat-free mass (right)	3.7	19.0	30.8	5.1	-0.8	5.5
Knee pain experienced in last month	3.7	5.8	9.5	-2.8	0.2	-3.1
Back pain experienced in last month	3.7	5.4	7.8	-2.7	-1.0	-2.8
Qualifications: A levels/AS levels or equivalent	3.5	7.7	12.3	3.5	0.2	3.3
Smoking status: Current	3.5	5.6	10.6	-3.2	-1.2	-2.2
Average weekly spirits intake	3.3	4.0	7.2	2.7	-1.1	2.0
Forced expiratory volume in 1-second (FEV1), predicted	3.2	6.6	11.4	2.8	-0.8	3.4
Friendships satisfaction	3.2	3.9	6.2	2.3	-0.2	2.5
Unable to work because of sickness or disability	3.2	4.2	6.1	-2.3	-1.0	-2.5
Arm predicted mass (left)	3.2	16.1	27.2	4.6	-0.4	5.2
Arm fat-free mass (left)	3.1	15.8	25.6	4.6	-0.9	5.1
Medication: Allopurinol	3.0	4.0	6.9	2.2	0.1	2.6
Blood Platelet Count	2.9	33.5	51.8	-6.8	1.6	-7.2
Townsend deprivation index at recruitment	2.9	4.1	7.0	-2.1	1.0	-2.6
Gout (self-reported)	2.9	4.0	6.5	2.3	0.3	2.6
Fed-up feelings	2.8	5.1	9.6	-2.3	-0.9	-3.1
High blood pressure	2.8	7.7	13.0	3.6	-1.1	3.0
Supplements: Vitamin C	2.7	3.2	4.3	1.9	-2.1	1.3
Tinnitus: Yes, now most or all of the time	2.7	3.2	5.1	-2.1	0.1	-2.2
Severe depression (siblings)	2.6	2.9	6.0	-1.5	0.6	-2.4
Illnesses of siblings	2.6	3.7	6.3	-2.5	0.8	-2.0
Breastfed as a baby	2.6	3.3	6.0	2.5	1.0	1.7
Medication: Amlodipine	2.6	3.7	6.0	2.5	-1.1	2.0
Age at last live birth	2.6	3.8	6.7	2.6	-0.9	2.0
Reaction Time	2.5	4.7	6.6	2.5	-1.1	2.6
Tense / ‘highly strung’	2.5	4.1	6.5	2.5	-0.2	2.4
Exposure to tobacco smoke outside home	2.5	3.3	8.3	-0.7	-2.9	-1.0
Hypertension (Self-reported)	2.5	6.8	11.6	3.4	-0.9	2.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.5	2.9	4.3	-1.7	-2.1	-1.2
Hearing aid user	2.5	2.8	5.2	-1.8	0.5	-2.3
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.8	7.6	-2.0	-0.2	-2.8
Exposure to tobacco smoke at home	2.4	2.7	4.2	-2.0	0.1	-2.0
Health satisfaction	2.3	3.0	5.6	1.8	0.4	2.4
Commuting to job workplace: Walk	2.3	2.5	2.9	-1.3	1.7	-1.7
Mean Putamen Volume	2.2	2.5	3.1	-1.4	-1.8	-1.6
Hair/balding pattern: Pattern 2	2.2	2.8	3.9	2.0	1.6	1.4
Neck or shoulder pain in last month	2.2	3.2	5.5	-1.7	-1.1	-2.3
Heart disease (mother)	2.2	2.7	3.4	1.5	1.8	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.2	2.6	4.3	2.1	-1.0	1.5
Medication: Lisinopril	2.2	2.9	4.1	2.0	-1.5	1.5
Vitamin and mineral supplements	2.1	2.9	5.2	-2.3	-0.2	-1.8
Forced vital capacity (FVC)	2.1	7.9	12.0	2.6	-2.2	3.5
Weight	2.1	10.4	15.8	3.9	-0.8	4.0
Falls in the last year	2.1	2.9	7.7	-0.5	-2.8	-0.8
Ever highly irritable/argumentative for 2 days	2.1	2.5	3.5	-1.8	-1.0	-1.9
High blood pressure (siblings)	2.1	3.1	5.5	2.4	-1.0	1.6
Pulse wave peak to peak time	2.1	2.5	5.2	-0.8	2.3	-1.3
Shortness of breath walking on level ground	2.1	2.5	3.0	-1.5	-1.5	-1.7
Mean time to correctly identify matches	2.1	4.1	6.5	2.4	-0.0	2.5
Pain type(s) experienced in last month: Hip pain	2.1	2.7	3.8	-1.9	0.8	-1.9
Vascular/heart problems diagnosed by doctor	2.0	5.4	8.2	-2.9	1.6	-2.4
Multivitamins +/- minerals	1.9	2.5	4.9	2.2	0.0	1.6
Hip circumference	1.9	8.2	13.0	3.4	-0.1	3.6
Peak expiratory flow (PEF)	1.9	4.3	5.5	2.2	-1.6	2.4
Long-standing illness, disability or infirmity	1.9	2.9	4.7	-1.9	-0.7	-2.2
Wears glasses or contact lenses	1.9	2.2	3.9	2.0	-0.6	1.5
Medication: Bendroflumethiazide	1.9	2.9	4.5	2.1	0.5	2.0
Commuting to job workplace: Cycle	1.9	2.4	3.5	1.9	0.6	1.8
Sensitivity / hurt feelings	1.8	3.1	3.4	1.8	-1.7	1.7
Father’s age at death	1.8	2.4	3.3	1.8	-1.0	1.8
Forced expiratory volume in 1-second (FEV1)	1.8	6.1	7.3	2.4	-2.3	2.7
Had major operations	1.8	2.1	4.1	-2.0	-0.0	-1.5
Alzheimer’s Disease (including proxy)	1.7	2.5	4.6	-2.1	-0.4	-1.7
Diabetes (father)	1.7	2.1	3.0	-1.6	-0.7	-1.7
Pulse wave reflection index	1.7	2.0	3.2	1.1	-1.8	1.3
Comparative body size at age 10	1.7	4.8	7.7	-2.6	0.4	-2.8
Wheeze or whistling in the chest in last year	1.7	2.9	4.4	-2.1	0.2	-2.1
Medication for pain relief, constipation, heartburn	1.7	2.8	5.7	0.3	2.4	1.7
Pulse rate, automated reading	1.7	5.6	8.8	-2.8	-0.2	-3.0
Mouth/teeth dental problems: Mouth ulcers	1.7	2.7	4.9	-1.6	0.7	-2.2
Ever depressed for a whole week	1.7	2.1	2.7	1.6	1.0	1.6
Depressed Affect (Nagel 2018)	1.6	3.4	5.9	-2.0	-0.7	-2.4
Medication: Co-codamol	1.6	1.8	2.8	-1.3	-1.0	-1.7
Age when periods started (menarche)	1.6	3.8	5.6	-2.4	-0.5	-2.4
Diabetes (self-reported)	1.6	2.4	3.7	1.9	-0.6	1.8
Fluid intelligence score	1.6	3.4	5.9	2.4	1.1	1.7
Forced vital capacity (FVC), Best measure	1.6	5.7	8.5	2.4	-1.7	2.9
Leg pain on walking	1.6	2.0	5.6	0.4	-2.4	0.5
Miserableness	1.6	2.8	4.4	-1.8	-0.8	-2.1
Bipolar Disorder (2018)	1.5	2.3	6.0	0.5	-2.5	0.8
Crohns Disease (2012)	1.5	2.4	4.1	1.8	0.0	2.0
Pulse rate	1.5	2.5	3.9	-2.0	1.0	-1.6
Illnesses of father: Heart disease	1.5	2.1	2.5	1.5	-1.2	1.6
Lung FVC	1.4	7.2	11.8	-3.4	-1.3	-2.9
Worrier / anxious feelings	1.4	2.6	3.2	1.8	-1.8	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.6	5.4	2.3	-1.9	2.2
Cardiovascular Disease	1.3	4.3	4.5	2.1	-2.1	2.0
Hearing difficulty/problems: Yes	1.3	1.9	5.4	0.4	2.3	-0.5
Had menopause	1.3	1.6	2.0	1.4	1.2	1.3
Ever unenthusiastic/disinterested for a whole week	1.3	1.5	4.1	0.1	-2.0	0.7
Medication: Blood pressure	1.3	2.3	3.9	2.0	-0.6	1.6
Overall health rating	1.3	2.8	4.4	-1.0	-2.1	-1.8
Chest pain or discomfort	1.3	1.9	2.1	-1.2	-1.4	-1.5
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	2.2	1.3	-0.9	1.5
Medication for cholesterol	1.3	2.0	3.1	-1.8	-0.3	-1.7
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	2.5	-1.5	-0.4	-1.6
Bipolar Disorder or Schizophrenia	1.2	2.9	3.6	1.6	-1.9	1.5
HbA1C	1.2	1.4	2.1	-1.5	0.2	-1.4
Medication: Atenolol	1.2	1.6	2.4	1.6	-1.0	1.1
Leg fat percentage (right)	1.2	4.3	7.2	-2.3	0.5	-2.7
Diabetes diagnosed by doctor	1.2	1.9	3.2	1.8	-0.6	1.5
Medication: Omeprazole (e.g. Zanprol)	1.2	1.5	2.0	-1.3	-0.9	-1.4
Verbal and Numeric Reasoning (VNR)	1.1	2.6	3.9	2.0	1.4	1.4
Systolic Blood Pressure	1.1	5.3	6.6	2.4	-1.9	2.6
Hearing difficulty/problems with background noise	1.1	1.7	2.9	-0.2	1.7	-1.5
Time employed in main current job	1.1	1.3	2.5	1.1	0.0	1.6
Loneliness, isolation	1.1	1.6	3.5	-1.1	-0.1	-1.9
Breast cancer (self-reported)	1.1	1.3	1.8	1.3	0.7	1.3
Illnesses of father: None of the above (group 1)	1.1	1.3	2.1	-0.7	1.5	-1.2
Myopia	1.1	1.6	4.7	-0.0	-2.2	0.1
Blood Eosinophil Count	1.0	7.7	15.1	2.8	-0.3	3.9
Allergy or Eczema	1.0	2.6	4.0	-1.9	-0.1	-2.0
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.6	0.6	-1.6	0.6
Maternal smoking around birth	1.0	1.4	3.1	-0.8	-0.7	-1.8
Taking other prescription medications	1.0	1.5	4.3	-0.5	-2.1	-0.2
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.5	0.8	1.6	0.8
Chronic bronchitis/emphysema (father)	1.0	1.2	1.9	-0.6	-1.4	-1.1
Alcohol usually taken with meals	1.0	1.7	2.6	1.5	0.5	1.6
Medication: Lansoprazole	1.0	1.1	1.4	1.2	-0.7	1.2
Blood clot in the leg (DVT)	1.0	1.2	1.8	-1.2	-0.6	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.4	-1.6	-0.3	-1.0
Qualifications: nursing, teaching	1.0	1.6	3.7	1.9	0.5	0.9
Leg fat percentage (left)	1.0	3.6	6.0	-2.2	0.2	-2.4
Number of operations (self-reported)	1.0	1.5	2.1	-1.4	-0.6	-1.4
Ever had prostate specific antigen (PSA) test	1.0	1.2	1.4	-0.9	1.2	-1.2
Age started oral contraceptive pill	1.0	1.2	2.4	0.8	0.8	1.6
Pack years adult smoking proportion	0.9	1.4	1.8	-1.3	-1.3	-0.9
Nervous feelings	0.9	1.7	3.0	1.2	-1.7	0.8
Allergy	0.9	2.0	2.3	1.5	1.2	1.5
Asthma	0.9	1.8	2.7	-1.6	-0.6	-1.6
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	1.5	1.1	1.2	1.0
Hypothyroidism/myxoedema (self-reported)	0.9	1.8	2.6	-1.4	-1.6	-1.0
Number of children fathered	0.9	1.0	1.6	-1.3	1.2	-0.3
Medication: Omeprazole	0.9	1.1	1.3	-0.9	-1.1	-1.0
Asthma (self-reported)	0.9	1.9	2.7	-1.6	-0.4	-1.6
Guilty feelings	0.9	1.4	3.3	0.0	-1.8	-0.9
Mother’s age at death	0.9	1.1	2.7	-1.6	-0.3	-0.7
Supplements: Fish oil (including cod liver oil)	0.9	1.2	3.1	-0.4	1.8	-0.6
Schizophrenia (2018)	0.8	1.6	2.7	1.7	-0.6	1.3
Prostate Cancer	0.8	1.2	2.0	0.8	-1.0	1.4
Primary Biliary Cirrhosis	0.8	1.1	3.3	-0.3	1.8	0.0
Impedance of leg (right)	0.8	3.8	6.4	-2.5	1.6	-1.5
Supplements: Glucosamine	0.8	1.1	1.6	-0.8	-1.2	-1.1
High blood pressure (mother)	0.8	1.1	2.0	1.4	1.1	0.4
Impedance of leg (left)	0.8	4.1	7.9	-2.8	1.2	-1.7
Lung cancer (father)	0.8	0.9	1.9	0.7	-1.4	-0.6
Hair/balding pattern: Pattern 4	0.8	2.0	5.8	-0.1	-2.4	0.4
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	2.5	1.0	-0.7	1.6
Glaucoma (self-reported)	0.8	0.9	2.5	-0.1	-1.6	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	1.3	-1.1	-0.3	-1.0
Alcohol drinker status: Previous	0.8	0.9	1.4	-1.2	0.1	-1.1
Worry (Nagel 2018)	0.7	1.6	2.4	1.6	-1.1	1.0
Heel T-Score	0.7	5.6	11.4	-1.8	3.4	-1.5
Respiratory disease	0.7	1.6	2.8	-1.7	0.1	-1.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.3	1.1	-0.7	0.6
Stomach or abdominal pain in last month	0.7	0.9	1.0	-0.9	-0.9	-1.0
Trunk fat mass	0.7	2.8	4.3	1.9	-0.7	2.1
Mouth/teeth dental problems	0.7	1.1	1.9	0.8	-1.4	0.9
Neuroticism score	0.7	1.5	3.8	0.7	-2.0	-0.5
Noisy workplace	0.7	0.9	1.3	-1.1	-0.4	-1.1
Headache pain in last month	0.7	1.2	1.6	-1.0	-1.3	-1.0
Number of full brothers	0.7	0.9	1.4	-0.3	-1.2	-1.1
Suffer from ‘nerves’	0.7	1.1	1.9	-0.2	-1.4	-1.1
Mood swings	0.7	1.2	2.8	-0.1	-1.7	-0.9
Financial situation satisfaction	0.7	0.8	1.5	-1.2	-0.3	-0.9
Intelligence (Savage-Jansen 2018)	0.6	1.9	2.5	1.6	1.5	1.1
Alzheimer’s Disease (in mother)	0.6	0.7	0.9	-0.8	-0.7	-1.0
Hypothyroidism (self reported)	0.6	1.4	1.9	-1.0	-1.4	-1.1
Chronotype (morning person)	0.6	1.3	3.4	0.5	1.8	0.5
Number of treatments/medications taken	0.6	1.0	3.0	-0.0	-1.7	-0.3
Relative age of first facial hair	0.6	1.3	2.0	0.9	1.0	1.4
Systolic blood pressure, automated reading	0.6	1.8	3.2	1.3	-0.7	1.8
Angina	0.6	0.7	1.5	0.7	-1.2	0.4
Qualifications: CSEs or equivalent	0.6	0.8	1.6	-0.8	-0.4	-1.2
Waist circumference	0.6	2.1	2.6	1.6	-1.1	1.5
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.2	0.7	-1.5	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	2.1	-1.3	0.3	-1.5
Number of live births	0.6	0.8	2.3	-0.3	-0.2	-1.5
Depression (self-reported)	0.6	0.7	1.7	0.7	0.1	1.3
Illnesses of mother	0.6	0.8	2.2	-0.4	-1.5	-0.1
Medication: Paracetamol	0.6	1.0	2.5	0.2	-1.6	-0.7
Medication: Ventolin 100micrograms inhaler	0.6	0.8	1.4	-0.8	-0.5	-1.2
Angina (self-reported)	0.6	0.8	1.7	0.8	-1.3	0.4
Fractured/broken bones in last 5 years	0.6	0.8	1.3	-1.1	0.1	-1.0
Breast Cancer	0.5	1.2	2.0	-0.7	1.0	-1.4
Neuroticism (2016)	0.5	0.7	1.6	0.7	-1.3	-0.3
Schizophrenia (2014)	0.5	1.0	1.8	0.8	-0.8	1.3
Hayfever, allergic rhinitis or eczema	0.5	1.0	1.1	-0.9	-1.0	-1.1
Medication: Simvastatin	0.5	0.7	1.0	1.0	-0.9	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.6	1.2	-0.6	0.1
Number of full sisters	0.5	0.7	1.3	-1.1	0.4	-0.8
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.0	0.3	-1.0	0.8
Average weekly beer plus cider intake	0.5	0.7	1.1	1.0	0.4	1.0
Diastolic blood pressure, automated reading	0.5	1.4	2.0	1.4	-0.5	1.4
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.6	-0.4	0.5	-1.3
Pack years of smoking	0.5	0.7	1.5	-0.7	-1.2	-0.2
Neuroticism (Nagel 2018)	0.4	0.9	1.7	-0.3	-1.3	-1.0
Blood Red Count	0.4	4.0	8.8	3.0	-0.1	1.8
Neuroticism	0.4	1.1	1.8	0.5	-1.4	-1.0
Frequency of depressed mood in last 2 weeks	0.4	0.5	0.9	0.9	-0.8	-0.3
Medication for hormone replacement therapy	0.4	0.4	1.1	0.1	0.4	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.2	-0.3	-0.3	-1.1
Medication: Levothyroxine sodium	0.4	0.6	1.1	-1.0	-0.8	-0.4
Financial difficulties in last 2 years	0.4	0.5	1.3	-0.5	0.0	-1.2
Heart attack	0.4	0.5	1.3	-0.4	0.2	-1.1
Arm fat percentage (right)	0.4	1.6	3.4	-1.1	-0.5	-1.8
Birth weight	0.4	0.8	1.3	-1.1	-0.5	-1.0
Worry too long after embarrassment	0.4	0.7	1.5	0.6	-1.2	-0.4
Mouth/teeth dental problems: Loose teeth	0.4	0.4	0.9	-0.1	0.9	-0.6
Migraine (self-reported)	0.4	0.5	0.5	0.6	-0.7	0.6
Medication: Aspirin	0.4	0.5	1.0	-0.5	-0.4	-1.0
Ever had bowel cancer screening	0.4	0.4	0.8	-0.9	-0.1	-0.7
Illnesses of father: High blood pressure	0.4	0.5	0.7	0.9	-0.5	0.8
Alzheimer’s Disease (in father)	0.3	0.3	0.7	-0.9	-0.3	-0.5
LDL Cholesterol	0.3	0.5	1.5	-1.2	0.0	0.0
Blood White Count	0.3	2.2	3.3	-1.8	0.1	-1.8
BMI	0.3	1.8	3.6	-0.7	-1.1	-1.9
Tanning	0.3	3.1	5.9	0.4	2.4	1.8
Medication: Metformin	0.3	0.4	0.9	0.9	-0.0	0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.8	0.3	-0.9	0.4
Serious illness, injury or assault to yourself	0.3	0.4	1.1	-0.1	-1.0	-0.4
Had other major operations	0.3	0.4	0.5	-0.6	-0.5	-0.7
Pain all over the body in last month	0.3	0.3	0.6	-0.6	-0.2	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.8	0.6	0.1	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.0	-0.0	-1.0	0.4
Birth weight of first child	0.3	0.6	1.6	-0.5	-1.3	0.0
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.9	-0.2	0.3	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	0.7	-0.6	-0.1	-0.9
Eye problems/disorders: None of the above	0.3	0.3	0.7	0.4	-0.8	-0.3
Emphysema/chronic bronchitis	0.3	0.4	0.7	-0.9	-0.0	-0.6
Whole body fat mass	0.3	1.1	1.4	1.1	-0.6	1.2
Arm fat percentage (left)	0.3	1.4	2.9	-0.9	-0.7	-1.7
Mineral and other dietary supplements	0.3	0.4	1.1	-0.4	-1.0	-0.1
Ever taken oral contraceptive pill	0.3	0.3	0.6	-0.4	0.5	-0.8
High cholesterol (Self-reported)	0.3	0.5	0.7	0.9	-0.5	0.7
Medication: Paracetamol	0.3	0.5	1.2	-0.1	-1.1	-0.3
Heart disease (siblings)	0.3	0.3	0.7	-0.6	0.8	0.0
Crohns Disease (2017)	0.2	0.4	0.7	0.7	-0.1	0.8
Ovarian Cancer	0.2	0.2	0.5	0.1	0.7	0.4
Fasting Glucose	0.2	0.2	0.4	-0.6	-0.2	-0.5
Rheumatoid Arthritis	0.2	0.2	0.4	0.6	-0.4	0.5
Ulcerative Colitis	0.2	0.3	0.8	-0.9	-0.4	-0.3
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.0	0.3	-1.0	-0.3
Hair Pigment	0.2	4.6	7.5	2.1	-2.7	1.3
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.3	0.6	0.5	0.5
Ever had hysterectomy (womb removed)	0.2	0.3	0.4	0.6	-0.6	-0.1
Diabetes (mother)	0.2	0.2	0.6	-0.1	-0.7	0.1
Relative age voice broke	0.2	0.3	0.4	0.3	0.6	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.2	-0.3	0.2	-1.1
Body mass index (BMI)	0.2	1.0	2.3	-0.7	-0.7	-1.5
Medication: Ramipril	0.2	0.3	0.5	0.7	-0.0	0.7
Mouth/teeth dental problems: Dentures	0.2	0.3	0.8	-0.4	0.9	-0.2
Prospective memory result	0.2	0.3	0.8	-0.1	-0.9	-0.0
Body fat percentage	0.2	0.8	1.3	-0.8	-0.5	-1.1
Medication: Seretide 50 evohaler	0.2	0.2	0.5	-0.3	-0.7	-0.2
Family relationship satisfaction	0.2	0.2	0.4	0.6	-0.0	0.6
Illnesses of siblings: Diabetes	0.2	0.3	0.7	-0.5	0.2	-0.8
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.6	0.1	0.2	0.8
Osteoporosis (self-reported)	0.2	0.3	0.5	-0.7	0.3	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.7	0.6	-0.4	0.8
Number of self-reported non-cancer illnesses	0.2	0.4	1.1	0.0	-1.1	0.2
Eye problems/disorders: Glaucoma	0.2	0.2	0.4	0.1	0.4	0.6
Irritability	0.2	0.3	0.9	-0.0	-0.9	0.0
Basal cell carcinoma (self-reported)	0.2	0.3	0.4	-0.6	0.6	-0.3
Irritable Bowel Disease (IBD)	0.1	0.3	0.6	0.4	-0.4	0.8
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	-0.5	0.0	0.0
HDL Cholesterol	0.1	0.1	0.3	0.5	0.0	0.0
Lupus	0.1	0.2	0.4	0.7	-0.0	0.4
Waist Hip Ratio (WHR)	0.1	0.5	1.3	-0.3	-1.1	-0.5
Hand grip strength (left)	0.1	0.3	0.7	0.4	-0.2	0.8
Supplements: Zinc	0.1	0.2	0.4	-0.7	0.1	-0.2
Average weekly fortified wine intake	0.1	0.2	0.3	-0.5	-0.0	-0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.3	-0.5	-0.5	0.1
Impedance of arm (right)	0.1	0.3	0.5	-0.1	0.6	0.7
Medication: Cholesterol lowering	0.1	0.2	0.5	0.3	-0.7	0.2
Impedance of arm (left)	0.1	0.4	1.1	0.4	0.1	1.1
Arm fat mass (right)	0.1	0.3	0.6	0.8	-0.5	0.4
Length of working week for main job	0.1	0.1	0.3	-0.1	-0.6	-0.1
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.3	-0.5	0.5	-0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.5	-0.3	-0.0	-0.7
Medication: Ibuprofen	0.1	0.1	0.1	0.4	-0.3	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.2	-0.5	-0.0	-0.4
Average weekly red wine intake	0.1	0.2	0.3	-0.3	0.5	-0.6
Eye problems/disorders: Cataract	0.1	0.1	0.2	0.1	0.5	0.3
Medication: Aspirin	0.1	0.1	0.3	-0.2	-0.1	-0.5
Medication: Gliclazide	0.1	0.1	0.3	-0.0	-0.3	-0.5
Arm fat mass (left)	0.1	0.5	0.7	0.8	-0.9	0.4
Alcohol drinker status: Never	0.1	0.2	0.3	0.5	-0.3	0.4
Risk taking	0.1	0.1	0.3	0.1	0.5	-0.1
Cholesterol lowering medication	0.1	0.1	0.1	0.2	-0.3	-0.4
Supplements: Calcium	0.1	0.2	0.3	-0.2	0.4	-0.5
Impedance of whole body	0.1	0.5	0.7	-0.9	0.8	0.1
Depression (Nagel 2018)	0.0	0.1	0.2	-0.1	0.1	-0.4
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis (UC)	0.0	0.1	0.1	-0.2	-0.3	0.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.1	-0.3	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0
Lung FEV1/FVC ratio	0.0	0.1	0.4	-0.1	0.1	-0.6
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.1	-0.0	-0.2	-0.1
Trunk fat percentage	0.0	0.1	0.4	0.2	-0.6	0.1
Hand grip strength (right)	0.0	0.1	0.1	-0.3	-0.3	0.3
Hair/balding pattern: Pattern 3	0.0	0.0	0.1	-0.4	-0.1	-0.1
Leg fat mass (right)	0.0	0.0	0.1	0.0	-0.1	-0.3
Commuting to job workplace: Public transport	0.0	0.1	0.1	-0.1	0.3	0.3
Medication: Atorvastatin	0.0	0.1	0.1	-0.3	-0.2	0.1
Leg fat mass (left)	0.0	0.0	0.1	0.1	-0.3	-0.1

Hub : Genes

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Trait associations