TWAS hub - STXBP6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2110	0.0380	8.5e-12	0.042	0.111	0.154	0.143	0.165	6.1e-06	2.2e-13	3.0e-18	5.2e-17	1.2e-19
2	GTEx	Brain Frontal Cortex BA9	0.3435	0.1145	7.0e-03	0.008	NA	0.020	NA	0.032	1.9e-01	NA	9.5e-02	NA	5.0e-02
3	GTEx	Cells Transformed fibroblasts	0.3310	0.0550	9.7e-13	0.276	NA	0.284	NA	0.292	8.0e-21	NA	1.7e-21	NA	3.9e-22
4	GTEx	Colon Sigmoid	0.2830	0.1100	9.4e-03	0.173	NA	0.150	NA	0.141	1.0e-06	NA	5.6e-06	NA	1.1e-05
5	GTEx	Colon Transverse	0.1640	0.0600	3.1e-03	0.102	NA	0.043	NA	0.067	1.4e-05	NA	4.2e-03	NA	4.2e-04
6	GTEx	Esophagus Muscularis	0.3130	0.0610	5.2e-09	0.154	NA	0.107	NA	0.149	1.3e-09	NA	4.8e-07	NA	2.6e-09
7	GTEx	Heart Left Ventricle	0.2630	0.0700	1.1e-04	0.078	NA	0.111	NA	0.125	5.7e-05	NA	1.7e-06	NA	3.5e-07
8	GTEx	Skin Not Sun Exposed Suprapubic	0.2570	0.0730	1.8e-04	0.007	NA	0.050	NA	0.024	1.3e-01	NA	1.0e-03	NA	1.6e-02
9	GTEx	Skin Sun Exposed Lower leg	0.1200	0.0380	1.8e-04	0.080	NA	0.044	NA	0.065	3.6e-07	NA	1.3e-04	NA	4.7e-06
10	GTEx	Stomach	0.1790	0.0730	3.6e-03	0.047	NA	0.043	NA	0.036	2.8e-03	NA	4.1e-03	NA	8.0e-03
11	GTEx	Thyroid	0.1320	0.0440	1.5e-03	0.089	NA	0.083	NA	0.088	2.6e-07	NA	6.9e-07	NA	2.9e-07
12	TCGA	Prostate Adenocarcinoma	0.0838	0.0348	1.1e-03	-0.002	0.020	0.012	NA	0.011	7.7e-01	3.3e-03	1.9e-02	NA	2.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Blood White Count	5.9	43.9	119.2	-10.9	-1.7	-5.4	-3.8	-4.9	-8.9	-8.6	-4.4	-7.1	-9.0	-3.5	4.6
Hair/balding pattern: Pattern 3	4.2	6.3	16.3	2.1	-0.8	1.8	2.4	2.6	3.3	4.0	1.1	3.2	3.4	1.4	-1.7
Neuroticism	4.1	9.8	16.8	-3.7	-2.8	-4.1	-3.4	-2.7	-3.0	-2.9	-2.8	-3.7	-3.8	-1.7	2.0
Ever had stillbirth, spontaneous miscarriage or termination	3.8	4.1	10.2	0.4	1.4	2.3	1.2	1.2	1.8	3.2	2.9	2.2	2.2	-0.9	-2.5
Loneliness, isolation	3.5	4.8	12.1	-1.8	-2.9	-1.4	-2.0	-2.8	-2.1	-0.3	-3.5	-2.2	-3.0	-0.8	0.2
Severe depression (siblings)	3.3	3.6	12.4	3.5	0.8	1.5	2.4	2.1	1.9	1.0	0.8	2.1	2.5	1.0	-1.1
Medication: Amlodipine	2.9	4.1	8.1	-2.5	-2.2	-0.3	-2.2	-2.3	-2.7	-1.5	-2.7	-1.1	-2.8	-1.2	0.5
Eye problems/disorders: None of the above	2.7	3.2	10.2	2.3	0.3	2.0	3.2	2.4	1.5	0.2	1.3	1.1	2.3	0.1	-1.5
Depressed Affect (Nagel 2018)	2.6	5.5	9.0	-2.7	-1.0	-2.7	-2.7	-2.2	-1.9	-2.6	-3.0	-2.2	-3.0	-2.4	0.4
Blood Eosinophil Count	2.6	19.9	42.6	-6.5	-0.2	-4.8	-3.4	-3.7	-6.4	-4.7	-3.1	-4.7	-5.8	-2.0	4.0
Average weekly champagne plus white wine intake	2.6	3.6	7.9	2.4	-0.2	1.2	2.0	2.3	2.4	2.8	1.5	1.6	2.5	1.1	-0.3
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.8	13.4	-2.4	-3.7	-2.1	-2.2	-0.2	-1.4	-0.5	-2.3	-1.8	-1.9	0.4	1.9
Number of incorrect matches in round	2.3	3.8	11.8	-1.4	-1.8	-2.7	-2.2	-1.3	-2.6	1.3	1.3	1.2	-1.6	0.3	3.4
Nervous feelings	2.3	4.4	11.3	-2.1	-2.9	-2.2	-2.2	-1.3	-1.2	-1.2	-2.8	-3.4	-2.1	-0.5	0.7
Irritability	2.3	4.0	13.6	-2.4	-3.7	-2.7	-1.3	-1.7	-1.9	-0.8	-1.6	-1.0	-2.0	-0.7	2.0
Neuroticism (Nagel 2018)	2.2	5.2	9.2	-2.4	-2.3	-3.0	-2.4	-2.1	-1.8	-1.9	-2.7	-2.4	-3.0	-1.2	1.2
Eye problems/disorders: Glaucoma	2.2	2.6	10.1	0.1	-0.3	-3.2	-2.2	-1.4	-1.0	-1.9	0.3	0.4	-1.9	0.1	2.3
Supplements: Zinc	2.1	2.3	5.6	1.4	-0.9	1.3	1.8	1.9	1.9	1.1	1.4	0.8	1.7	2.4	0.2
Neuroticism score	2.0	4.2	9.6	-2.6	-3.0	-3.1	-2.0	-0.5	-0.6	-1.7	-2.4	-2.5	-1.6	-1.8	0.3
Mouth/teeth dental problems: Dentures	2.0	3.4	11.0	-2.4	-0.9	-0.3	-1.9	-2.7	-2.4	-0.1	-3.3	-1.4	-1.7	-1.3	-0.4
Wheeze or whistling in the chest in last year	2.0	3.6	8.9	-2.0	-3.0	-2.0	-2.9	-1.2	-2.1	-2.1	-1.2	-0.5	-2.4	-0.1	0.8
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	7.1	0.9	-0.4	0.1	2.2	1.5	2.7	-0.1	1.7	1.9	2.0	-0.6	-1.2
Depression (Nagel 2018)	1.9	2.9	8.1	-2.8	-1.5	-1.2	-2.5	-0.6	-1.0	-1.4	-1.8	-1.6	-1.9	-2.1	0.2
Ovarian Cancer	1.9	2.5	7.9	1.2	0.9	-0.8	-0.3	-2.6	-2.8	-0.5	-0.5	0.4	-1.8	2.1	2.2
Serious illness, injury or assault to yourself	1.9	2.3	4.8	-0.9	-0.4	-1.4	-2.2	-1.5	-1.4	-1.6	-2.0	-2.0	-2.1	-0.4	0.9
Falls in the last year	1.9	2.6	6.2	0.1	-1.7	-1.4	-1.8	-2.5	-1.1	0.2	-1.2	-1.3	-2.0	2.4	1.5
Suffer from ‘nerves’	1.9	3.0	13.5	-1.3	-1.2	-1.2	-1.3	-1.2	-0.7	-1.2	-3.0	-3.7	-1.7	-0.7	0.6
Long-standing illness, disability or infirmity	1.9	2.9	6.7	-2.2	-2.3	0.1	-1.6	-1.5	-1.6	-1.2	-1.9	-1.9	-2.6	0.2	1.5
Ever had bowel cancer screening	1.9	2.2	11.8	2.3	0.5	1.0	0.6	-0.2	0.1	1.3	1.2	1.5	0.8	3.4	1.3
Number of self-reported non-cancer illnesses	1.9	3.3	7.4	-2.3	-2.7	-0.8	-1.1	-1.8	-2.5	-0.7	-2.6	-1.3	-1.9	-0.8	1.5
Supplements: Fish oil (including cod liver oil)	1.9	2.4	7.0	0.7	-0.4	1.0	1.6	2.6	2.5	0.9	0.8	1.4	2.3	-0.7	-1.7
Medication: Omeprazole (e.g. Zanprol)	1.9	2.3	6.0	1.5	-1.9	0.5	1.7	2.4	1.8	0.8	0.5	2.3	1.9	0.3	0.3
Supplements: Vitamin C	1.8	2.1	6.0	2.1	0.6	0.9	1.1	1.3	2.5	1.0	0.9	1.2	2.0	1.8	-0.7
Eye problems/disorders: Cataract	1.7	1.9	5.2	-2.3	-1.1	-2.0	-1.7	-1.8	-1.5	0.4	-1.1	-1.1	-1.2	-0.4	0.6
Pack years of smoking	1.7	2.6	7.8	-0.4	-0.1	2.8	0.7	2.2	2.2	0.6	-0.6	0.8	1.9	-0.2	-2.8
Worry (Nagel 2018)	1.6	3.3	8.2	-2.2	-2.9	-2.0	-1.4	-1.0	-0.9	-1.2	-2.5	-2.0	-2.0	-1.5	0.2
HbA1C	1.6	1.8	4.7	-1.1	0.7	-0.4	-1.7	-2.1	-1.3	-1.0	-1.7	-0.4	-2.2	-1.3	0.1
Respiratory disease	1.6	3.6	8.8	-3.0	-1.4	-0.8	-1.3	-2.2	-2.6	-1.4	-2.0	-2.1	-2.4	-1.0	0.9
Vitamin and mineral supplements	1.6	2.2	5.2	-0.3	-0.0	-1.5	-0.8	-2.1	-1.8	-2.0	-2.0	-2.3	-1.7	-0.1	0.5
Angina (self-reported)	1.6	2.1	7.8	-0.9	-2.2	2.8	-1.5	-1.1	0.6	0.0	-2.1	-1.0	-0.8	-1.1	-0.7
Medication: Omeprazole	1.6	1.9	6.2	0.8	-2.5	0.8	1.7	1.9	1.6	0.7	-0.8	1.4	1.7	0.1	-0.1
Mood swings	1.6	2.9	6.9	-2.1	-0.4	-2.6	-1.4	-0.9	-0.2	-2.3	-2.1	-2.6	-1.2	-1.6	0.2
Mineral and other dietary supplements	1.6	2.2	6.5	-0.1	1.0	-1.4	-1.3	-2.5	-1.8	-1.8	-0.8	-1.3	-2.1	0.6	1.4
Ulcerative Colitis	1.5	2.2	9.4	-1.3	0.3	-2.0	-0.0	-0.8	-1.8	-3.1	-0.4	-1.2	-1.9	-1.5	0.4
Exposure to tobacco smoke at home	1.5	1.7	6.7	-1.1	-1.1	0.5	0.1	-1.6	-2.2	0.3	-2.6	-1.5	-1.1	0.4	-0.4
Blood clot in the leg (DVT)	1.5	2.0	4.7	-0.7	0.5	-1.2	-2.2	-2.0	-2.2	1.0	-0.3	-1.2	-1.9	-1.0	0.9
Glaucoma (self-reported)	1.5	1.8	6.0	0.7	0.4	-2.5	-1.2	0.0	-0.6	-2.1	1.0	1.3	-0.8	0.9	2.2
Emphysema/chronic bronchitis	1.5	1.7	7.7	-2.8	-0.1	-0.7	-1.5	-2.0	-2.0	-0.4	0.2	-0.4	-0.9	-0.5	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	7.0	-2.6	-0.6	-1.1	-0.5	-1.4	-1.4	-0.3	-0.9	-2.1	-1.4	0.2	1.3
High cholesterol (Self-reported)	1.5	2.7	10.9	-2.0	-0.9	-0.5	-0.5	-1.8	-1.8	-1.3	-3.3	-1.8	-1.5	-1.7	-0.2
Cholesterol lowering medication	1.5	2.2	5.1	-1.8	-0.0	0.3	-1.0	-1.3	-0.8	-2.1	-2.3	-1.5	-1.6	-1.9	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.5	1.9	5.4	-0.9	0.4	-1.2	-2.1	-1.8	-2.3	1.1	-0.3	-0.9	-1.8	-1.1	1.1
Alzheimer’s Disease (in mother)	1.4	1.6	6.0	1.5	0.2	0.5	-0.7	2.5	1.4	0.2	1.3	2.2	1.1	0.5	0.5
Coronary Artery Disease (CAD)	1.4	1.7	3.6	0.6	0.9	1.9	1.3	-0.3	1.9	1.5	-0.8	-0.3	1.4	1.3	-1.8
Frequency of depressed mood in last 2 weeks	1.4	1.9	4.5	-1.6	-2.1	-1.4	-1.3	-0.3	-1.1	-1.2	-2.1	-0.9	-1.5	-1.1	0.7
Angina	1.4	1.9	7.0	-0.9	-2.2	2.6	-1.3	-1.2	0.6	-0.1	-1.8	-1.0	-0.8	-1.1	-0.7
Multivitamins +/- minerals	1.4	1.8	5.6	0.4	-0.6	1.3	-0.1	2.4	1.6	1.2	1.9	1.8	1.6	-0.4	-0.2
Alcohol drinker status: Previous	1.4	1.6	3.4	0.1	-1.6	1.0	1.8	1.8	1.7	0.9	-0.8	-0.3	1.4	0.6	-1.7
Alzheimer’s Disease (including proxy)	1.3	1.9	9.6	2.0	0.3	0.6	0.2	3.1	2.1	-0.3	0.6	0.7	1.4	0.7	0.6
Neuroticism (2016)	1.3	1.9	7.1	-0.6	-0.4	-2.7	-1.9	-1.2	-1.4	-1.0	-0.7	-0.7	-1.9	-1.7	-0.1
Ever had hysterectomy (womb removed)	1.3	1.5	3.7	-1.6	-0.6	1.4	0.9	0.6	1.1	0.2	-1.9	-1.2	0.8	-1.1	-1.8
Pack years adult smoking proportion	1.3	2.1	6.0	-0.2	0.0	2.3	0.9	2.2	2.1	-0.0	-0.5	0.6	1.7	0.1	-2.4
Hearing difficulty/problems with background noise	1.3	2.1	5.3	2.3	-1.6	0.1	-0.8	-1.1	0.1	1.9	0.9	2.3	-0.0	2.2	1.3
Had other major operations	1.3	1.6	3.1	-1.6	1.2	-0.9	-1.4	-0.7	-1.7	-0.3	-1.5	-1.0	-1.8	-0.7	1.5
Mouth/teeth dental problems	1.3	2.0	3.7	1.9	0.5	1.5	0.6	1.9	1.9	1.2	1.7	1.7	1.6	0.4	-0.7
Hayfever/allergic rhinitis (self-reported)	1.3	1.8	6.1	1.8	-0.1	0.6	-2.4	-0.9	-1.0	0.1	0.3	0.0	-0.9	2.5	1.8
Medication: Simvastatin	1.3	2.0	4.1	-1.8	-0.9	-0.9	-1.2	-1.9	-1.5	-1.9	-2.0	-0.9	-1.5	-1.0	0.0
Time employed in main current job	1.3	1.5	4.1	-0.4	0.2	1.9	2.0	2.0	1.3	0.5	1.1	0.6	1.4	-0.1	-0.7
Birth weight of first child	1.3	2.4	5.3	-1.1	-0.3	-1.4	-2.3	-1.3	-1.7	-2.1	-1.0	-2.0	-2.0	0.1	1.4
Exposure to tobacco smoke outside home	1.3	1.7	5.0	-0.8	-1.6	-2.2	-1.6	-0.9	-1.0	-1.0	-1.4	-1.8	-0.9	-0.9	-0.5
Medication: Allopurinol	1.3	1.7	8.9	0.6	1.5	-0.4	-0.4	1.3	3.0	0.5	0.5	-0.1	1.6	-1.3	-1.4
Heart disease (mother)	1.3	1.6	6.7	-0.9	0.2	-0.7	-1.5	-1.0	-1.1	-1.4	-2.6	-1.6	-1.3	-0.0	0.1
Age at last live birth	1.3	1.8	13.9	1.2	3.7	0.9	0.9	0.2	-0.7	-1.3	-0.6	-0.8	-0.1	1.3	-0.0
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	4.8	-1.3	-0.1	-1.4	-0.4	-0.8	-1.5	-1.2	-0.4	-2.2	-1.6	-0.1	1.6
Medication: Aspirin	1.3	1.7	4.2	0.2	0.2	1.4	2.0	0.6	1.2	2.1	-0.1	1.8	1.5	-0.1	-1.5
Breast cancer (self-reported)	1.3	1.6	5.5	-1.4	-0.5	-0.1	-2.4	-1.1	-1.5	-0.2	-1.8	-1.6	-1.2	0.4	0.8
Asthma (self-reported)	1.3	2.7	5.4	-1.9	-1.5	-0.5	-2.1	-1.7	-2.0	-0.7	-2.1	-2.3	-1.9	-0.7	0.6
Type 2 Diabetes (T2D) (2012)	1.2	1.4	4.4	1.4	0.2	-2.1	0.0	1.5	0.6	0.1	1.0	0.7	2.0	1.1	1.0
Average weekly fortified wine intake	1.2	1.4	3.7	1.9	1.2	0.8	1.9	0.9	1.8	0.4	0.2	-0.1	1.2	0.1	-1.0
Fed-up feelings	1.2	2.1	7.1	-1.9	-0.7	-2.7	-1.5	-0.3	-0.9	-1.4	-1.6	-1.2	-1.0	-2.0	-0.1
Qualifications: A levels/AS levels or equivalent	1.2	2.7	9.2	2.0	3.0	2.0	1.1	1.8	1.6	0.3	1.4	1.2	1.4	1.4	-0.4
Asthma	1.2	2.3	6.5	-1.7	-1.2	-0.0	-1.9	-1.7	-1.7	-0.6	-1.9	-2.6	-1.7	-0.8	0.3
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	6.7	2.1	-0.2	-0.2	-2.0	-0.9	-1.4	-0.3	-0.5	1.1	-1.4	1.2	2.6
Mouth/teeth dental problems: Loose teeth	1.2	1.4	4.7	0.1	1.1	-0.7	0.1	0.2	-2.1	-1.6	1.6	-0.1	-0.6	1.0	2.2
Hearing aid user	1.2	1.3	2.8	1.7	1.2	1.1	-0.9	1.1	1.7	0.2	-0.7	1.0	1.3	0.8	-1.3
Number of operations (self-reported)	1.2	1.8	7.4	-1.1	1.2	0.4	-2.7	-0.8	-0.8	-0.7	-2.0	-1.2	-1.5	-0.5	1.1
Risk taking	1.2	1.8	8.9	0.9	0.0	1.7	1.3	0.5	0.1	1.3	1.9	3.0	0.9	-0.9	-0.1
Heart disease (siblings)	1.2	1.4	5.5	-1.1	0.4	-0.4	-0.5	-1.7	-2.4	-0.5	-1.2	-0.7	-2.0	-0.1	0.8
Hypothyroidism (self reported)	1.1	2.5	9.9	-3.1	0.2	-1.6	-0.6	-0.1	-1.3	-2.2	-1.1	-2.2	-1.5	-1.6	0.5
Average weekly spirits intake	1.1	1.4	5.7	0.7	2.4	1.7	0.7	0.6	1.3	0.1	0.1	-0.4	1.6	-0.7	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	6.2	-1.3	-0.9	-1.2	-1.3	-0.2	-0.9	-0.9	-2.5	-1.7	-0.6	-1.3	-0.2
Relative age voice broke	1.1	1.6	3.6	1.9	0.3	-0.2	1.6	1.0	1.6	1.1	0.6	1.9	1.3	-1.7	-0.3
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	7.4	-2.0	-1.1	-1.7	-0.5	-0.1	-0.6	-0.7	-2.7	-1.8	-0.6	0.1	-0.1
Pain all over the body in last month	1.1	1.1	8.3	-1.3	0.4	-0.3	0.7	1.0	0.3	-0.2	2.9	-0.6	0.9	-0.6	0.0
Fluid intelligence score	1.1	2.3	8.4	2.9	2.7	1.7	1.0	-0.2	0.9	1.9	-0.1	-0.1	0.7	0.3	-1.6
Noisy workplace	1.1	1.4	5.0	-1.6	-0.9	-2.2	-1.8	-0.8	-0.7	-0.5	0.6	-1.1	-1.0	0.0	1.0
Breastfed as a baby	1.1	1.4	9.8	0.0	3.1	0.6	1.4	0.0	-0.2	1.0	1.4	-0.6	-0.0	0.7	0.6
Number of full brothers	1.1	1.4	5.7	-0.1	0.5	2.4	1.7	0.0	-0.2	1.2	-0.3	-0.8	0.7	0.5	-2.1
Age at first live birth	1.1	1.9	10.4	2.0	3.2	1.4	1.3	1.0	0.3	-0.3	-0.3	0.0	1.1	1.3	-0.5
Overall health rating	1.1	2.4	10.8	-2.1	-2.9	-0.4	-1.1	-0.2	-0.6	-0.5	-3.3	-1.2	-1.1	-0.6	-0.1
Had major operations	1.1	1.2	10.9	0.2	-1.0	0.5	-3.3	-0.2	0.5	-0.2	-1.0	-0.3	-0.4	-0.6	-0.8
Illness, injury, bereavement, stress in last 2 years	1.1	1.4	4.5	-0.7	0.7	1.3	0.0	0.6	1.5	0.7	-0.2	1.5	0.7	-1.8	-2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	2.9	1.7	-1.6	0.5	0.6	1.6	1.7	0.3	0.7	1.5	1.1	0.1	-0.3
Qualifications: nursing, teaching	1.1	1.7	5.0	2.1	1.0	1.0	1.2	2.2	1.2	-0.9	0.9	1.2	0.9	1.2	1.0
Osteoporosis (self-reported)	1.1	1.4	3.7	-1.9	-0.3	-1.6	-0.4	0.2	-0.7	-1.7	-0.8	-1.9	-0.7	-0.5	1.0
Medication: Aspirin	1.1	1.5	3.3	-0.0	-0.4	1.3	1.8	0.6	1.3	1.8	-0.9	1.7	1.3	-0.2	-1.4
Miserableness	1.1	1.9	5.9	-1.5	-1.0	-2.4	-1.3	-0.7	-1.2	-0.7	-1.4	-1.1	-0.9	-2.2	-0.6
Fractured/broken bones in last 5 years	1.1	1.4	4.3	-2.1	-2.0	-1.6	-0.9	-0.5	-1.2	1.4	1.2	-0.4	0.1	0.0	0.5
Supplements: Calcium	1.1	1.2	3.8	0.4	-0.8	1.0	0.5	1.0	0.1	1.9	1.7	1.9	0.9	0.5	0.9
Reaction Time	1.0	2.0	5.7	-1.6	-1.6	-2.4	-1.1	-1.0	-0.9	-0.5	-1.7	-1.4	-1.4	-0.6	1.4
Rheumatoid Arthritis	1.0	1.4	5.2	-1.7	-2.3	-1.5	-0.9	0.1	-1.1	-1.6	-0.6	-0.1	-0.8	0.6	0.8
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	5.2	-2.3	-1.2	0.2	-1.0	-1.0	-0.6	0.9	-0.1	0.2	-0.8	-1.4	-0.3
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	5.3	0.3	0.8	-0.3	-0.1	0.7	0.1	-0.1	2.3	0.8	0.5	1.9	1.7
Forced vital capacity (FVC)	1.0	3.7	13.5	1.6	2.2	-1.8	-3.7	-1.1	-0.6	-2.4	-0.2	-1.5	-1.9	1.3	2.4
Allergy	1.0	2.3	7.5	0.1	-0.7	0.2	2.7	1.4	0.7	1.8	1.7	2.7	1.8	0.9	0.1
Gout (self-reported)	1.0	1.4	7.1	1.7	0.8	0.4	-0.4	1.3	2.7	0.3	0.7	0.2	1.6	-0.5	-1.0
Medication: Ibuprofen	1.0	1.1	4.3	-0.8	-0.3	-2.1	-0.4	-1.3	-0.9	-1.4	-0.1	-0.6	-1.2	-1.5	-0.1
Medication: Seretide 50 evohaler	1.0	1.1	5.6	-2.4	0.5	0.2	-0.7	0.3	-0.8	-0.8	-1.4	-0.8	-0.7	-1.5	0.2
Mean time to correctly identify matches	1.0	2.0	5.1	-2.2	-1.8	-2.3	-1.0	-1.0	-1.0	0.2	-1.5	-1.2	-1.2	-0.3	1.5
Guilty feelings	1.0	1.5	5.0	-1.9	-1.1	-2.2	-0.9	-0.8	-1.2	-0.7	-0.1	-1.4	-1.0	-0.5	1.1
Wears glasses or contact lenses	1.0	1.1	2.8	-1.0	-0.1	0.6	0.7	1.5	1.1	1.7	0.3	1.0	0.8	-1.6	-1.0
Mother’s age at death	1.0	1.3	3.0	-1.4	-0.1	1.6	0.5	-1.7	-0.7	1.3	-1.4	0.1	-0.9	-1.4	-0.9
Prostate Cancer	0.9	1.2	3.1	-0.6	0.3	1.5	0.9	1.7	1.0	0.7	-0.3	0.7	1.7	-0.8	-1.6
Blood Platelet Count	0.9	9.9	22.1	-4.7	-1.8	-2.7	-1.4	-3.0	-4.5	-3.5	-1.7	-3.0	-4.3	-2.3	2.5
Medication for hormone replacement therapy	0.9	1.0	2.1	1.4	-0.2	1.2	-0.1	0.8	0.7	1.3	0.3	1.4	0.7	1.5	1.3
Townsend deprivation index at recruitment	0.9	1.3	4.3	1.6	-0.5	-2.1	-0.7	-0.7	-1.9	0.3	-1.2	-0.3	-0.7	0.7	1.0
Taking other prescription medications	0.9	1.3	3.8	-0.7	-1.0	-1.0	-1.1	-0.2	-0.9	-1.4	-1.6	-1.0	-1.4	-0.3	2.0
Alcohol usually taken with meals	0.9	1.5	5.1	0.9	0.1	0.4	1.4	1.7	1.3	0.3	1.5	2.3	1.0	-1.2	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	3.3	1.1	1.8	-0.6	1.6	-0.9	-0.5	0.4	0.4	-0.5	0.0	1.5	0.8
Hair/balding pattern: Pattern 4	0.9	2.1	8.1	1.7	2.1	-0.8	-0.1	-1.1	-1.4	-0.8	-0.1	-0.7	-0.9	2.1	2.8
Chest pain or discomfort	0.9	1.3	7.0	-1.1	-2.6	-1.2	-1.2	-0.2	-0.2	-0.9	-1.3	-0.8	-1.0	0.2	0.2
Ever smoked	0.9	1.5	3.4	-1.2	1.2	-0.5	0.5	-1.5	-1.9	-1.6	-1.4	-0.5	-1.7	-0.7	1.2
Ever had prostate specific antigen (PSA) test	0.9	1.0	5.1	-0.1	1.0	-0.2	-0.1	-0.7	-1.6	-0.1	-2.2	0.9	-0.6	-1.3	-0.0
Bipolar Disorder (2018)	0.8	1.3	5.3	2.3	0.3	0.1	0.2	1.0	0.9	0.7	1.4	1.6	0.9	1.6	0.2
Verbal and Numeric Reasoning (VNR)	0.8	2.0	6.8	2.0	2.6	1.6	1.6	-0.5	0.7	1.3	-0.9	-0.3	0.4	-0.5	-2.2
Breast Cancer	0.8	1.8	6.9	0.2	-0.2	-0.7	-2.6	-1.9	-1.4	-1.0	-1.3	-0.4	-1.9	0.4	1.6
Cardiovascular Disease	0.8	2.8	11.0	-3.3	-1.7	-1.4	-1.0	-0.6	-1.6	-1.7	-1.6	-0.5	-1.2	-2.4	-0.9
Medication: Co-codamol	0.8	0.9	2.9	-1.3	-0.6	0.9	0.6	1.4	0.3	1.1	-0.8	0.1	0.4	-1.7	-0.9
Diabetes (mother)	0.8	1.1	7.6	-1.2	-2.8	0.6	0.1	-0.4	-0.3	-0.3	-0.1	-0.6	-0.6	-1.3	-1.0
Medication: Atenolol	0.8	0.9	6.2	-1.1	2.5	-0.4	0.2	-0.3	0.2	0.4	0.8	0.1	-0.1	-1.1	-1.2
Number of live births	0.8	1.1	7.6	0.9	2.8	-0.4	0.2	0.5	-0.1	0.2	1.5	-0.6	0.6	0.9	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	4.8	-0.5	-1.1	-1.8	0.9	2.2	0.2	-1.2	1.1	0.8	0.3	-0.5	0.9
Peak expiratory flow (PEF)	0.8	1.8	6.2	1.7	2.5	-0.9	-0.7	1.6	1.2	-2.0	1.0	1.1	0.2	0.2	0.7
Number of children fathered	0.8	0.9	2.7	-1.6	-0.2	0.9	0.3	1.0	1.2	-0.1	-0.5	0.4	1.1	-1.0	-1.3
Neck or shoulder pain in last month	0.8	1.1	4.1	-0.7	-1.7	-2.0	-1.0	-1.1	-0.9	-0.4	-0.6	-0.3	-1.2	0.6	0.8
Diabetes diagnosed by doctor	0.8	1.4	4.8	-1.7	-2.1	-1.8	0.1	0.6	-0.6	-0.1	0.4	0.3	-0.1	-2.2	-0.5
Osteoarthritis (self-reported)	0.8	1.0	3.3	-1.5	-0.3	1.6	-0.9	-0.1	0.6	0.7	-0.7	-0.8	0.3	-1.8	-1.1
Commuting to job workplace: Public transport	0.8	0.9	3.2	-0.8	1.0	-0.9	0.2	-0.3	-0.3	-1.8	-0.7	-0.8	-0.8	-1.5	-1.1
Commuting to job workplace: Cycle	0.8	1.0	3.7	0.5	-0.6	-0.3	-0.9	1.9	0.9	0.7	1.7	0.9	0.6	0.4	1.0
Alzheimer’s Disease (in father)	0.7	0.7	1.6	1.3	0.6	-0.9	0.4	0.9	0.7	-0.8	-1.0	-0.8	0.6	1.1	1.0
Ulcerative Colitis (UC)	0.7	1.2	3.5	-1.1	0.5	-1.0	-0.4	-0.9	-1.9	-1.8	-1.0	-0.8	-1.6	-0.7	-0.0
Bipolar Disorder (2011)	0.7	0.7	2.5	-0.2	-0.4	-0.8	0.2	-0.7	0.2	-1.4	-0.7	-1.2	-0.6	-1.6	-0.4
HDL Cholesterol	0.7	1.2	4.3	-0.1	-0.3	0.5	-2.1	-2.0	-1.1	1.3	0.8	-0.6	-1.1	0.4	-0.2
LDL Cholesterol	0.7	1.0	5.6	2.4	0.7	0.2	1.3	-0.3	0.0	1.9	0.2	0.5	0.7	0.5	-0.1
Primary Biliary Cirrhosis	0.7	1.0	5.5	-0.1	-1.1	-1.2	-0.9	0.1	-0.2	-2.3	-0.4	-0.7	-0.7	1.2	0.7
Smoking Status	0.7	1.7	7.0	-2.6	-2.3	-1.4	0.2	-0.2	-0.8	-1.4	-1.1	-0.1	-1.1	-1.3	0.3
Number of treatments/medications taken	0.7	1.3	7.7	-1.4	-0.6	0.4	-0.5	-0.2	-0.7	-0.9	-2.8	-1.2	-1.2	-0.8	0.7
Maternal smoking around birth	0.7	1.0	4.1	0.1	-2.0	0.8	1.5	0.3	0.2	0.0	0.7	1.2	1.0	-0.8	-0.9
Chronic bronchitis/emphysema (father)	0.7	0.9	3.4	0.6	-0.8	1.2	0.1	0.7	1.8	1.2	0.8	0.8	1.2	0.1	-0.3
Hair/balding pattern: Pattern 2	0.7	0.9	3.2	-1.6	-1.8	-0.5	-0.2	0.4	-0.3	-1.4	0.0	-1.0	-0.4	-0.9	0.3
Had menopause	0.7	0.9	2.5	0.3	0.9	-0.9	0.2	1.1	0.2	1.3	1.6	0.9	1.1	0.5	0.8
Ever unenthusiastic/disinterested for a whole week	0.7	0.8	2.9	-0.8	-0.8	1.2	0.4	0.7	-0.3	-1.1	0.0	0.4	-0.1	-1.6	-1.7
Heart attack	0.7	0.9	3.4	-0.2	0.2	-0.5	-1.1	-1.5	-0.0	-0.7	-1.8	-1.4	-0.9	-0.2	-0.3
Diabetes (self-reported)	0.7	1.0	3.9	-1.3	-2.0	-1.4	0.1	0.7	-0.4	-0.2	0.6	0.0	0.0	-1.9	-0.5
Father’s age at death	0.7	1.0	5.4	-0.8	0.4	2.3	1.2	-0.1	-0.2	1.3	-0.0	-0.0	0.5	0.8	-1.1
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	6.4	1.7	2.4	-1.8	-2.5	-0.1	0.2	-2.1	0.6	-0.7	-1.2	0.7	1.7
Medication: Cholesterol lowering	0.7	1.2	6.1	-0.7	-1.8	0.9	0.6	-0.8	-0.6	1.0	-2.5	-0.5	-0.1	-0.4	-0.7
Prospective memory result	0.7	0.8	3.7	-1.5	-1.9	-0.5	-1.6	0.2	-0.8	0.2	-0.3	-0.2	-0.2	-0.3	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	7.8	0.7	2.8	-1.7	-2.0	-0.6	0.2	-2.7	0.2	-1.3	-1.3	-0.5	0.8
Pulse wave Arterial Stiffness index	0.7	0.9	2.4	-0.8	0.2	-1.1	-0.7	-1.3	-1.5	-0.8	0.9	-0.9	-0.9	0.8	0.3
Hypothyroidism/myxoedema (self-reported)	0.7	1.5	5.7	-2.4	-0.0	-0.2	0.1	0.5	-0.8	-2.0	-1.4	-1.7	-0.9	-0.8	0.6
Chronic bronchitis/emphysema (mother)	0.7	0.8	2.1	-0.3	-1.2	0.2	0.6	0.8	1.0	1.3	0.9	-0.1	1.4	0.7	-0.8
Forced vital capacity (FVC), Best measure	0.7	2.6	7.3	0.7	2.7	-1.1	-2.5	-1.3	-0.4	-2.6	-0.1	-1.7	-1.7	-0.1	1.1
Worry too long after embarrassment	0.7	1.1	4.3	-1.2	-1.0	-2.1	-1.2	0.3	-0.1	-0.4	-0.5	-1.4	-0.9	-1.1	0.8
Pulse wave peak to peak time	0.7	0.9	2.4	0.8	-0.4	1.2	0.4	1.2	1.6	0.8	-0.7	1.2	0.9	-0.9	-0.3
Commuting to job workplace: Car/motor vehicle	0.7	0.8	3.8	1.1	0.4	0.8	0.4	1.2	0.6	-0.1	-0.6	-0.0	0.8	2.0	0.7
Average weekly red wine intake	0.7	1.1	3.0	0.5	1.6	-1.7	-0.5	-1.1	-1.0	-1.3	0.4	0.0	-1.2	0.4	1.0
Commuting to job workplace: Walk	0.7	0.7	2.9	0.8	1.6	-0.6	1.0	0.2	0.5	-0.2	1.7	0.4	0.7	-0.5	-0.1
Medication: Atorvastatin	0.7	0.8	3.9	-0.3	-0.9	2.0	0.5	0.6	-0.2	1.1	-1.3	0.1	0.4	-0.7	-1.0
Heart attack/myocardial infarction (self-reported)	0.7	0.9	3.1	-0.4	0.1	-0.5	-1.2	-1.6	-0.2	-0.5	-1.8	-1.2	-0.9	-0.2	-0.4
Bipolar Disorder or Schizophrenia	0.6	1.5	3.4	1.3	-0.0	-0.3	0.8	1.9	0.9	0.7	1.3	1.8	1.6	1.7	0.9
Major Depression (MDD)	0.6	0.7	3.0	0.6	1.7	1.5	0.6	0.4	0.8	-0.7	0.8	0.6	0.3	0.7	0.3
Body Mass Index (BMI) (2010)	0.6	0.8	2.2	-0.1	-0.7	0.1	0.4	1.2	1.4	-0.4	-0.5	0.6	1.4	-0.9	-1.5
Triglycerides	0.6	1.0	5.0	0.6	-0.9	-0.1	2.2	-0.3	1.0	1.1	0.7	-0.3	0.9	-0.2	-1.4
BMI	0.6	3.3	8.0	0.1	-0.7	2.0	1.2	2.5	2.4	0.8	-0.7	1.9	2.4	-1.7	-2.8
Type 2 Diabetes (T2D) (2018)	0.6	1.1	3.8	-1.3	-2.0	-1.4	-0.4	-0.6	-1.4	-0.4	-0.1	-0.2	-0.7	-1.5	0.1
Medication: Metformin	0.6	0.9	3.7	-1.3	-0.6	-1.4	-0.4	0.5	-0.1	-0.2	0.1	0.1	0.4	-1.9	-1.4
Hand grip strength (right)	0.6	1.8	5.4	1.2	0.7	0.7	-0.1	1.6	2.3	0.7	0.9	2.2	1.1	-1.3	-1.4
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.0	-1.7	-1.0	-0.4	-1.1	0.7	-0.5	-0.4	-0.8	0.6	-0.4	-0.4	0.0
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.2	1.1	-0.6	1.1	0.3	1.1	0.7	-0.4	-0.1	1.5	0.1	0.4	-0.5
Hayfever, allergic rhinitis or eczema	0.6	1.3	5.3	1.6	1.4	0.3	-2.3	0.1	0.4	-1.2	-1.5	-0.7	-0.9	0.5	0.4
Stomach or abdominal pain in last month	0.6	0.7	5.8	-1.3	-2.4	-0.2	0.2	-0.1	-0.1	0.5	0.3	-0.7	-0.4	-0.1	0.2
Financial difficulties in last 2 years	0.6	0.8	2.8	1.4	-1.1	0.7	-0.8	-0.6	-0.1	-0.5	0.1	-0.3	-0.2	1.7	1.2
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.6	-0.2	0.1	-1.3	-0.5	-1.6	-0.6	-0.8	-0.2	-1.1	-1.1	-0.6	0.2
Depression (self-reported)	0.6	0.7	2.4	-1.1	-1.4	0.3	0.5	1.5	0.4	-0.2	0.4	-0.1	0.0	-1.2	0.3
Tense / ‘highly strung’	0.6	1.0	2.3	-1.1	-1.5	-1.1	1.1	0.5	-1.1	-0.0	-1.1	-0.8	-0.1	0.9	1.2
Ever highly irritable/argumentative for 2 days	0.6	0.8	3.6	-0.9	-1.9	-0.6	-0.6	0.1	-1.3	-0.3	0.5	-0.7	-0.2	0.4	1.1
Medication: Paracetamol	0.6	1.0	5.7	0.7	-0.1	0.3	-2.4	-1.1	-0.7	0.1	0.5	-0.9	-1.5	0.2	0.8
Headache pain in last month	0.6	1.0	2.2	-1.3	-0.9	-0.8	0.1	-1.2	-0.9	-0.2	-1.2	-1.4	-1.5	-0.8	-0.3
Birth weight	0.6	1.2	4.6	0.0	-1.0	-1.1	-2.1	-0.4	-1.2	-0.9	1.1	-0.5	-1.4	-0.2	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.1	0.1	-1.5	-0.4	-1.0	0.3	-1.4	-1.0	-0.1	-0.6	-1.1	-0.5	1.3
Health satisfaction	0.6	0.8	1.9	-1.2	-1.4	1.1	0.6	0.8	0.6	1.1	-0.0	0.0	0.6	-1.0	-1.3
Shortness of breath walking on level ground	0.6	0.8	3.0	-1.4	0.3	0.5	0.1	0.5	0.6	1.7	0.6	-0.0	0.8	-0.8	-1.3
Qualifications: College or University degree	0.6	1.7	5.9	2.4	1.8	1.4	0.3	0.9	1.6	1.3	1.4	1.1	0.9	0.6	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.9	-1.7	0.7	-0.3	0.7	0.4	0.2	-0.3	1.6	0.6	0.9	0.0	0.4
Alcohol intake frequency.	0.6	1.4	5.7	-1.6	-1.3	0.3	-0.3	-0.3	-1.1	-0.5	-2.4	-2.0	-0.7	0.6	-0.8
Knee pain experienced in last month	0.6	0.9	3.2	-0.5	0.1	1.3	-0.2	1.2	1.8	0.8	-0.3	0.1	1.1	-1.2	-1.2
Illnesses of father: Heart disease	0.6	0.8	2.8	-1.7	-0.5	0.4	-0.6	-0.8	-0.9	1.5	-0.4	-0.7	-0.6	-1.2	-0.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.9	-0.5	-0.3	-0.3	0.8	1.3	1.4	-0.7	-0.4	-0.5	1.2	-0.1	-1.3
Ever taken oral contraceptive pill	0.6	0.6	2.0	0.1	-1.2	1.4	0.2	0.6	0.3	0.9	1.4	-0.1	0.7	0.5	0.3
Medication: Paracetamol	0.6	0.9	3.8	0.2	0.0	-0.4	-2.0	-0.9	-1.2	-0.9	0.1	-0.2	-1.6	-0.0	0.8
Medication: Lisinopril	0.6	0.8	5.2	-0.3	0.2	-0.1	-0.0	1.0	1.1	-0.6	-0.3	0.4	0.2	-2.3	-1.2
Illnesses of father: High blood pressure	0.6	0.8	4.4	-0.6	0.0	-1.1	-0.7	-0.3	-0.5	-1.1	-0.7	-2.1	-0.7	-0.2	0.4
Average weekly beer plus cider intake	0.6	0.9	2.7	-1.0	-0.2	-0.9	-0.3	-1.4	-1.0	-1.3	0.1	-0.1	-1.6	-0.8	0.3
Schizophrenia vs Biploar Disorder	0.5	0.7	2.7	-1.6	-1.2	-0.2	0.5	-0.7	-1.4	-0.1	-0.7	-0.6	-0.4	0.2	0.4
Age at First Birth	0.5	0.7	3.2	1.4	-0.2	-0.1	0.2	0.9	-0.3	1.0	0.4	0.9	0.2	1.8	-0.0
Mean Putamen Volume	0.5	0.5	4.1	0.1	2.0	-0.7	-0.3	0.2	0.6	-0.8	-0.6	-0.3	-0.0	-0.5	-0.3
Fasting Glucose	0.5	0.6	2.4	0.7	-1.6	0.2	0.2	1.2	1.3	-0.4	0.4	-0.1	0.3	-0.3	-0.4
Lupus	0.5	0.7	2.3	-1.0	-1.5	-0.1	0.1	1.1	1.5	0.2	-0.9	-0.3	0.3	0.6	-0.0
Qualifications: None of the above	0.5	1.1	3.3	-1.3	-0.5	-0.4	1.2	1.2	0.5	0.5	-0.1	0.3	1.6	-1.3	-1.8
Alcohol intake versus 10 years previously	0.5	0.7	2.8	-1.7	-0.1	-1.1	-0.4	-0.2	-1.1	-0.3	-0.8	-0.7	-0.1	-1.5	-0.1
Worrier / anxious feelings	0.5	1.0	3.8	-1.0	-1.0	-2.0	-0.5	1.3	0.7	-0.8	-0.9	-1.4	-0.2	-0.7	-0.2
Pulse rate	0.5	0.9	3.5	0.9	-0.0	-1.9	-0.1	0.7	-0.5	-1.0	1.6	0.2	0.3	1.1	0.8
Happiness	0.5	0.6	2.6	-0.2	-1.0	-1.2	1.6	0.4	0.4	-0.8	-0.6	-0.4	0.0	-0.9	-0.4
Pulse wave reflection index	0.5	0.6	2.2	-0.8	0.5	0.4	-0.4	-1.5	-1.0	-0.2	-1.0	-0.2	-1.2	-0.3	0.0
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.5	-0.1	-1.6	1.1	-0.3	-0.1	0.6	-0.2	0.2	-0.4	-0.4	-1.2	-1.2
Migraine (self-reported)	0.5	0.7	4.2	-0.0	-0.4	-0.1	-0.7	-0.2	-0.7	-0.9	0.6	-0.4	-0.7	1.0	2.1
Family relationship satisfaction	0.5	0.6	2.0	0.7	-1.4	-1.2	0.1	-0.2	-0.1	0.7	-0.1	1.0	-0.0	0.4	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	4.0	2.0	0.8	0.4	0.0	1.1	1.8	-0.7	0.4	-0.1	1.2	0.4	-0.0
Smoking status: Current	0.5	0.8	4.2	-2.0	-1.2	-0.7	-0.4	0.1	-0.3	-1.1	-0.7	-0.4	-0.7	-0.7	-0.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.8	-0.1	0.2	-0.3	1.3	0.4	0.3	0.1	0.9	0.8	1.0	-1.3	-0.7
Pain type(s) experienced in last month: Hip pain	0.5	0.7	4.6	-0.8	-2.2	-0.1	0.3	-0.2	-0.3	-0.3	-0.8	-0.2	-0.5	-0.6	-1.1
Leg fat percentage (left)	0.5	1.8	4.7	-1.5	-2.2	0.4	1.2	0.7	0.9	0.2	-0.5	1.1	1.4	-2.0	-2.2
Ever depressed for a whole week	0.5	0.6	2.6	0.0	0.3	-0.0	1.1	0.2	-0.7	-1.1	1.6	0.4	0.1	0.5	-0.7
Vascular/heart problems diagnosed by doctor	0.5	1.4	7.0	2.3	2.6	0.2	1.3	-0.2	0.2	0.2	1.4	-0.2	0.4	1.0	0.2
Pain experienced in last month	0.5	0.9	5.6	1.6	2.4	-0.2	-0.7	-0.8	-0.3	0.2	-0.7	-0.2	0.1	0.9	0.3
Basal cell carcinoma (self-reported)	0.5	0.6	1.9	0.1	0.4	-0.4	-0.9	1.4	0.7	-1.3	1.0	0.4	0.1	0.3	1.1
Intelligence (Savage-Jansen 2018)	0.4	1.2	4.3	1.3	1.4	1.1	0.4	-0.7	0.7	2.1	-0.6	-0.0	0.4	-0.9	-1.7
Schizophrenia (2018)	0.4	0.7	2.5	-0.2	-0.3	-0.4	0.9	1.6	0.4	0.3	0.6	1.0	1.3	1.0	1.0
Waist Hip Ratio (WHR)	0.4	1.6	4.0	-2.0	-0.8	-1.4	-0.8	-1.3	-1.5	-0.4	-1.8	-1.0	-1.6	-0.8	1.0
Allergy or Eczema	0.4	1.0	2.9	0.6	1.3	0.3	-1.4	-0.5	-0.1	-1.4	-1.7	-1.3	-1.0	-0.1	0.2
Lung FVC	0.4	2.3	8.9	0.2	2.4	-0.8	-3.0	-0.8	-0.4	-2.1	-0.9	-1.5	-1.6	-0.2	1.1
Hand grip strength (left)	0.4	0.9	4.3	0.8	0.8	1.0	0.4	0.8	1.2	0.9	-0.1	2.1	0.8	-0.6	-0.7
Hearing difficulty/problems: Yes	0.4	0.5	1.5	0.7	-1.2	0.7	-0.9	-0.7	0.3	-0.0	0.2	1.2	-0.2	1.0	0.2
Relative age of first facial hair	0.4	0.8	2.5	0.8	0.7	0.5	1.6	-0.4	0.2	1.2	1.5	0.6	0.5	1.1	0.4
Trunk fat percentage	0.4	1.4	5.5	-0.8	-2.3	0.8	0.2	0.8	1.4	0.4	-0.5	1.0	1.4	-1.1	-1.7
Current tobacco smoking	0.4	0.6	3.0	-1.7	-1.0	-0.5	-0.6	-0.1	-0.4	-1.2	-0.7	-0.6	-0.8	-0.0	-0.0
Age when periods started (menarche)	0.4	0.9	3.9	0.9	1.4	2.0	-0.2	-0.4	-0.3	-0.6	-0.8	-1.1	-0.3	0.9	0.6
High blood pressure	0.4	1.2	6.7	-1.3	-2.6	-0.5	-1.1	0.6	-0.0	-0.0	-1.3	1.0	-0.1	-1.0	-0.2
Medication: Levothyroxine sodium	0.4	0.7	2.4	-1.1	0.8	0.4	-0.3	0.5	-0.3	-1.5	-0.4	-1.0	-0.9	0.1	1.3
Body mass index (BMI)	0.4	1.6	4.3	-0.8	-2.0	0.5	1.0	1.3	1.2	0.6	-0.3	1.2	1.5	-1.5	-2.1
Past tobacco smoking	0.4	0.6	1.6	1.1	-0.2	0.4	-1.0	0.5	1.2	0.8	1.3	-0.4	0.6	0.3	-0.9
Hip circumference	0.4	1.7	4.3	0.8	-0.8	0.6	0.3	2.1	1.9	0.3	1.5	1.5	1.9	-0.5	-1.4
Length of working week for main job	0.4	0.4	2.3	0.6	0.6	0.0	0.7	0.3	0.1	-0.8	1.5	-0.1	-0.4	0.2	0.6
Loud music exposure frequency	0.4	0.4	1.9	-0.5	0.4	-1.4	-1.3	-0.2	-0.2	-0.3	0.1	-0.5	-0.3	-0.3	-0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	5.0	0.9	0.8	-0.2	-0.3	0.5	0.8	-0.8	2.2	0.2	-0.0	0.3	0.6
Body fat percentage	0.4	1.5	5.1	-0.8	-2.3	0.6	0.5	0.8	1.4	0.4	-0.5	1.0	1.4	-1.6	-1.9
Leg fat percentage (right)	0.4	1.3	3.9	-1.2	-1.9	-0.1	0.9	0.5	0.7	-0.1	-0.0	0.9	1.1	-2.0	-1.7
Pulse rate, automated reading	0.4	1.2	6.0	2.4	-0.3	-0.4	0.7	1.3	1.8	-1.4	0.0	-0.6	0.9	0.2	-0.7
Comparative height size at age 10	0.4	2.2	8.8	-0.5	0.6	-2.9	-3.0	-0.8	-1.5	-1.1	0.7	-0.7	-1.3	0.5	1.4
Leg pain on walking	0.4	0.5	2.9	-0.3	-1.7	-0.5	-1.1	0.5	0.1	0.3	0.2	1.2	0.0	-0.2	-0.2
Hypertension (Self-reported)	0.4	1.2	6.9	-1.5	-2.6	-0.0	-1.0	0.9	-0.2	-0.1	-0.9	1.1	0.1	-1.0	-0.5
Arm fat percentage (left)	0.4	1.4	4.7	-0.9	-2.2	0.6	0.6	0.7	1.2	0.4	-0.8	1.0	1.1	-1.7	-1.7
Friendships satisfaction	0.4	0.5	1.5	0.9	-1.1	-0.4	0.9	-0.5	-0.5	1.2	-0.1	0.5	0.4	-0.6	-0.3
Medication for cholesterol	0.4	0.6	1.8	1.1	0.8	-0.3	1.3	-0.4	0.3	1.3	0.6	-0.2	0.8	-0.0	-0.5
Medication: Gliclazide	0.4	0.5	1.7	-0.2	-0.8	-0.5	1.1	0.1	-0.8	1.3	-0.4	-0.2	0.5	-0.3	0.6
Illnesses of father: None of the above (group 1)	0.4	0.4	2.1	-0.6	1.0	-0.6	0.6	0.1	-0.2	-1.4	0.2	0.5	-0.0	-0.4	-0.8
Medication: Blood pressure	0.4	0.7	2.9	-1.1	-0.9	-0.4	-0.9	1.0	0.2	-1.7	-0.5	0.5	-0.9	-0.4	0.5
Alcohol drinker status: Never	0.4	0.5	2.1	-0.2	0.0	-1.0	0.0	0.8	0.4	-1.4	-0.7	0.2	-0.3	-0.5	-1.1
Diastolic blood pressure, automated reading	0.4	1.1	4.4	0.4	-0.3	-0.1	-0.3	1.9	1.2	0.6	0.6	2.1	1.4	-0.6	-1.0
Leg fat mass (left)	0.4	1.4	3.3	-0.8	-1.8	0.2	0.6	1.3	1.3	0.4	0.4	1.4	1.6	-1.3	-1.7
Irritable Bowel Disease (IBD)	0.3	0.7	1.4	-0.2	1.0	-0.3	-0.7	-1.1	-1.1	-1.1	-0.9	-1.1	-1.2	-0.7	-0.1
Crohns Disease (2012)	0.3	0.5	1.2	-0.4	-0.4	-0.8	-0.8	-0.5	0.3	-1.0	-1.1	-0.6	-0.7	-0.8	-0.1
Schizophrenia (2014)	0.3	0.7	4.5	0.5	-0.2	-0.0	-0.2	0.7	0.0	-0.1	0.1	1.0	0.6	2.1	1.3
Heel T-Score	0.3	2.4	8.6	2.9	1.3	0.8	0.4	0.7	1.6	2.4	0.1	2.2	1.8	-1.1	-0.2
Systolic Blood Pressure	0.3	1.5	3.5	-1.7	-0.2	-0.7	-1.9	-1.0	-1.8	-0.8	-1.3	0.8	-1.5	-1.3	-0.5
Sensitivity / hurt feelings	0.3	0.5	3.0	-0.0	-1.7	-1.0	0.3	0.6	1.1	-0.1	0.4	-0.4	0.2	-0.3	0.4
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.8	-0.2	0.1	0.3	-0.8	0.6	-0.1	-0.3	-0.6	1.3	-0.2	-1.4	0.2
Systolic blood pressure, automated reading	0.3	0.8	2.4	-1.5	-0.3	-0.4	-0.5	-0.3	-1.2	1.2	-0.9	1.1	0.2	-1.0	-0.5
Diabetes (father)	0.3	0.4	1.8	0.2	-0.6	-0.6	-0.9	0.9	0.0	0.1	-0.1	1.3	0.1	-0.7	0.6
High blood pressure (mother)	0.3	0.5	1.5	0.6	-1.2	0.3	0.6	-1.0	-0.1	-0.5	-1.0	-0.4	-0.7	0.5	-0.1
Trunk fat mass	0.3	1.1	3.4	-0.4	-1.8	0.5	-0.3	0.9	1.6	0.5	0.1	1.1	1.3	-0.9	-1.5
Illnesses of siblings	0.3	0.5	1.8	-0.0	0.5	-0.9	-0.4	-0.3	0.7	-1.4	0.6	-0.6	-0.3	-0.1	1.1
Arm fat percentage (right)	0.3	1.3	4.7	-0.9	-2.2	0.6	0.5	0.7	0.9	0.4	-0.9	0.8	1.0	-1.7	-1.5
Medication: Lansoprazole	0.3	0.3	1.8	0.8	-0.7	-0.0	-0.6	-0.2	0.3	0.3	-0.4	-0.0	-0.3	0.2	1.3
Illnesses of mother	0.3	0.3	1.2	-0.2	1.1	-0.2	-0.2	-1.1	-0.7	0.9	-0.2	-0.4	0.0	-0.1	0.1
Standing height	0.3	2.9	10.8	1.6	1.6	-1.7	-3.3	0.9	0.4	-0.1	2.8	0.7	-0.2	1.6	1.9
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.8	0.2	-0.4	-1.7	0.2	-0.2	-0.1	-0.3	-0.4	-0.0	0.1	0.5	0.9
High blood pressure (siblings)	0.3	0.5	1.2	0.6	0.1	-0.9	-0.7	0.6	-1.1	0.6	0.3	1.1	-0.2	0.8	0.6
Medication: Blood pressure	0.3	0.6	3.1	-0.7	-1.1	0.1	-1.1	-0.1	-0.4	0.9	-1.8	0.1	-0.1	-0.2	-0.2
Whole body fat mass	0.3	1.3	3.5	-0.2	-1.9	0.7	0.1	1.1	1.7	0.7	-0.1	1.2	1.6	-0.9	-1.6
Leg fat mass (right)	0.3	1.2	2.6	-0.6	-1.6	-0.1	0.6	1.3	1.3	0.3	0.6	1.3	1.5	-1.2	-1.5
Illnesses of siblings: Diabetes	0.3	0.4	1.3	-0.4	-0.1	-0.2	0.3	0.7	0.2	0.9	-0.2	0.3	0.3	-1.1	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.0	0.3	1.1	-0.9	0.8	0.3	0.1	-0.0	1.0	1.4	0.2	0.8	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.0	-0.4	1.4	-0.3	-1.3	-0.6	0.1	-1.3	-0.5	-0.6	-0.8	-0.5	0.3
Arm fat mass (left)	0.3	1.1	3.0	-0.4	-1.7	0.3	0.3	1.0	1.3	0.5	-0.3	1.1	1.3	-1.0	-1.6
Financial situation satisfaction	0.3	0.4	1.2	1.0	-0.2	-0.1	-0.6	-0.0	0.4	-0.7	-1.1	0.5	-0.3	-0.9	-0.4
Medication: Bendroflumethiazide	0.3	0.5	1.8	-0.6	-1.3	0.7	0.1	0.3	-0.1	-0.6	0.3	0.9	0.1	1.2	0.7
Arm predicted mass (left)	0.3	1.4	4.8	0.2	0.2	-0.1	-0.7	2.1	1.1	1.1	2.2	1.4	1.6	0.4	-0.5
Crohns Disease (2017)	0.2	0.4	0.9	0.6	0.7	0.6	-0.9	-0.9	0.1	0.2	-0.9	-0.9	-0.5	-0.3	0.2
Height	0.2	3.2	15.9	0.5	0.1	-2.1	-4.0	1.8	0.6	1.0	3.1	1.3	0.2	1.1	0.7
Lung FEV1/FVC ratio	0.2	1.1	4.0	0.3	1.4	-0.5	1.1	2.0	1.2	0.7	0.2	1.2	1.4	0.3	0.1
Chronotype (morning person)	0.2	0.5	1.2	0.0	-0.3	0.4	0.8	0.8	1.1	-0.3	0.6	0.8	0.7	0.5	-1.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.9	-0.5	-0.2	1.0	0.2	0.0	0.2	0.2	-0.3	-0.4	-0.7	0.5	0.8
Leg fat-free mass (left)	0.2	1.0	3.2	0.5	-0.1	-0.6	-0.9	1.6	1.2	0.5	1.8	1.4	0.9	0.1	-0.2
Qualifications: CSEs or equivalent	0.2	0.3	0.8	0.9	0.0	0.6	0.6	-0.6	-0.1	0.2	0.4	0.7	-0.1	0.4	0.4
Supplements: Glucosamine	0.2	0.3	0.8	-0.1	0.7	0.1	0.1	0.9	0.4	0.8	-0.8	0.2	0.2	-0.9	-0.2
Sitting height	0.2	1.3	3.6	1.9	-0.1	-0.1	-1.3	1.5	1.8	-0.2	1.5	0.4	0.9	1.3	0.1
Leg predicted mass (left)	0.2	1.0	3.2	0.5	-0.2	-0.6	-0.9	1.7	1.3	0.6	1.8	1.5	1.0	0.1	-0.2
Waist circumference	0.2	0.6	2.3	-0.7	-1.5	-0.2	-0.0	1.1	0.6	0.4	0.0	0.6	0.8	-0.8	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.7	0.0	0.5	-0.3	0.8	0.0	0.8	0.5	0.7	0.1	0.9	-1.3	-1.1
Medication: Ramipril	0.2	0.3	0.9	0.1	-0.8	0.7	-1.0	0.4	0.6	-0.1	-0.5	-0.1	0.2	1.0	0.1
Weight	0.2	1.0	2.3	-0.2	-1.2	-0.3	-0.5	1.5	1.2	0.5	1.0	1.4	1.2	-0.8	-1.1
Trunk fat-free mass	0.2	1.1	4.5	0.6	0.7	-1.1	-1.8	1.3	0.7	0.3	2.1	0.8	0.5	0.5	0.3
Lung cancer (father)	0.2	0.3	1.0	0.2	-0.2	0.1	1.0	0.2	0.1	-0.1	-1.0	0.7	0.5	0.3	0.1
Arm fat mass (right)	0.2	0.9	2.5	-0.2	-1.6	0.5	0.3	0.9	1.1	0.6	-0.3	1.1	1.2	-0.9	-1.5
Trunk predicted mass	0.2	1.1	4.5	0.6	0.7	-1.1	-1.8	1.3	0.6	0.3	2.1	0.8	0.4	0.5	0.4
Arm fat-free mass (right)	0.2	1.0	3.3	0.3	-0.3	-0.6	-1.2	1.6	1.0	0.5	1.8	1.3	1.0	0.5	-0.4
Comparative body size at age 10	0.2	0.6	2.5	0.8	0.3	-0.3	-0.7	-1.6	-0.4	0.2	-0.6	-0.4	-1.5	-0.6	0.6
Arm predicted mass (right)	0.2	0.9	2.8	0.2	-0.1	-0.5	-1.3	1.5	0.9	0.5	1.7	1.1	1.0	0.5	-0.5
Number of full sisters	0.2	0.3	1.3	-1.1	-0.4	0.2	-0.1	0.5	-0.3	0.6	1.0	-0.2	0.3	-0.3	-0.3
Smoking status: Previous	0.2	0.3	1.7	-0.2	0.5	-0.3	1.3	0.1	-0.4	-0.4	-0.6	0.6	0.3	-0.0	0.5
Whole body fat-free mass	0.2	1.0	4.2	0.5	0.2	-0.7	-1.4	1.5	1.0	0.5	2.0	1.1	0.7	0.3	-0.1
Leg fat-free mass (right)	0.2	1.0	3.0	0.4	-0.1	-0.2	-0.7	1.7	1.3	0.7	1.5	1.3	1.1	0.1	-0.5
Back pain experienced in last month	0.2	0.2	0.8	0.2	-0.9	0.1	0.1	0.6	0.7	-0.4	0.4	0.8	-0.1	0.5	0.0
Whole body water mass	0.2	1.0	3.6	0.4	0.1	-0.7	-1.4	1.6	1.0	0.5	1.9	1.1	0.8	0.2	-0.2
Leg predicted mass (right)	0.2	1.0	3.2	0.3	-0.1	-0.2	-0.7	1.8	1.4	0.8	1.6	1.4	1.1	-0.1	-0.6
Basal metabolic rate	0.2	1.0	3.3	0.4	-0.0	-0.5	-1.1	1.6	1.2	0.6	1.8	1.2	1.0	0.0	-0.4
Arm fat-free mass (left)	0.2	1.0	3.8	0.0	-0.3	-0.2	-0.8	1.8	1.0	0.7	2.0	1.1	1.3	0.3	-0.5
Age started oral contraceptive pill	0.2	0.3	0.5	-0.6	-0.7	-0.6	-0.6	-0.7	-0.3	0.7	0.7	-0.5	-0.3	0.6	0.1
Unable to work because of sickness or disability	0.2	0.3	0.9	-0.9	-0.6	-1.0	0.6	-0.4	-0.2	0.3	0.0	-0.4	-0.6	-0.6	0.5
Blood Red Count	0.1	1.1	3.4	-0.8	0.0	-1.2	-0.5	-0.5	-1.3	-0.6	-1.6	-1.8	-0.5	-1.0	1.0
Tanning	0.1	1.1	3.7	0.9	-0.2	1.5	0.1	-1.2	0.7	-0.3	-1.4	-1.7	-0.1	1.9	-0.1
Impedance of leg (right)	0.1	0.5	1.5	0.4	0.1	-0.5	-0.8	-1.2	-0.7	-1.1	0.0	-0.9	-0.8	0.1	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.5	-0.0	-0.5	-0.2	0.4	0.3	0.6	0.3	0.2	-0.2	0.7	-0.2	-0.3
Impedance of arm (right)	0.1	0.4	1.1	0.8	0.0	0.1	-0.7	-1.0	-0.3	-0.6	0.1	-0.5	-0.9	0.1	1.0
Impedance of arm (left)	0.1	0.3	1.3	0.8	0.1	0.0	-0.6	-1.1	0.0	-0.5	-0.2	-0.5	-0.8	0.3	0.7
Myopia	0.1	0.2	0.5	-0.5	-0.5	-0.0	0.7	0.0	-0.3	0.3	0.2	0.1	0.4	0.7	-0.5
Hair Pigment	0.0	0.4	2.2	0.0	0.3	0.5	0.3	0.9	1.5	-0.5	-0.1	0.0	-0.2	-0.7	-0.8
Impedance of leg (left)	0.0	0.2	1.2	-0.1	-0.1	0.3	-0.2	-1.1	-0.5	-0.5	-0.6	-0.7	-0.3	0.0	-0.2
Medication for pain relief, constipation, heartburn	0.0	0.1	0.2	-0.3	-0.3	0.3	0.3	0.2	-0.1	-0.5	0.2	-0.2	0.2	-0.0	-0.4
Impedance of whole body	0.0	0.2	1.0	0.6	0.1	0.4	-0.5	-1.0	-0.1	-0.5	-0.2	-0.4	-0.4	0.3	0.4

Hub : Genes

STXBP6

Models

Trait associations