TWAS hub - SYBU

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Nerve Tibial	0.116	0.0355	7.9e-06	0.046	NA	0.053	NA	0.062	0.00034	NA	0.00012	NA	3.4e-05
2	GTEx	Ovary	0.205	0.0910	3.7e-03	0.006	NA	-0.012	NA	-0.007	0.23000	NA	0.82000	NA	5.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Ever unenthusiastic/disinterested for a whole week	6.2	7.6	7.7	-2.8	2.7
Hearing aid user	4.2	4.7	9.3	-0.5	3.0
Ever depressed for a whole week	4.1	5.1	5.4	-2.3	2.2
HbA1C	4.0	4.4	8.0	0.9	-2.8
Number of live births	3.9	5.6	11.1	0.3	-3.3
Pulse wave Arterial Stiffness index	3.7	4.4	8.7	3.0	-0.1
Pulse wave peak to peak time	3.7	4.4	8.8	-3.0	-0.0
Reaction Time	3.6	6.8	12.1	-3.5	1.2
Medication: Ventolin 100micrograms inhaler	3.6	4.6	8.7	2.9	-0.8
Ever used hormone-replacement therapy (HRT)	3.5	4.5	7.8	-1.1	2.8
Fed-up feelings	3.5	6.3	12.5	3.5	-0.2
LDL Cholesterol	3.4	5.4	7.9	-1.7	2.8
Type 2 Diabetes (T2D) (2018)	3.3	6.2	10.2	3.2	-1.4
Bilateral oophorectomy (both ovaries removed)	3.2	3.7	6.8	2.6	-0.7
Mean time to correctly identify matches	3.2	6.1	8.8	-3.0	1.9
Age at First Birth	2.9	4.2	8.1	-2.9	0.4
Alcohol drinker status: Previous	2.9	3.3	6.4	-2.5	0.4
Wheeze or whistling in the chest in last year	2.8	5.0	6.1	2.5	-2.0
Unable to work because of sickness or disability	2.7	3.4	6.9	0.2	-2.6
Number of incorrect matches in round	2.6	4.3	5.3	-1.8	2.3
Qualifications: nursing, teaching	2.6	4.1	4.4	-1.9	2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.4	3.2	5.7	2.4	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.3	4.8	7.8	-2.8	1.3
Commuting to job workplace: Cycle	2.2	2.6	5.3	-2.3	0.1
Loneliness, isolation	2.1	2.9	5.8	2.4	0.2
Sensitivity / hurt feelings	2.0	3.3	6.2	2.5	0.7
Ulcerative Colitis	1.9	2.8	3.0	-1.6	1.7
Neuroticism score	1.9	3.9	7.7	2.8	0.4
Medication: Blood pressure	1.9	3.3	6.6	-0.2	2.6
Illnesses of father: Heart disease	1.9	2.6	4.1	1.0	-2.0
Glaucoma (self-reported)	1.8	2.1	2.7	1.6	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.2	4.3	0.2	2.1
Knee pain experienced in last month	1.8	2.8	5.3	2.3	-0.6
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	3.2	1.8	1.1
Neuroticism	1.7	4.2	8.3	2.9	-0.3
Chronic bronchitis/emphysema (father)	1.7	2.0	2.8	-1.1	1.7
Had menopause	1.7	2.1	4.2	0.0	2.0
Mouth/teeth dental problems	1.7	2.7	3.2	-1.5	1.8
Ever taken oral contraceptive pill	1.7	1.9	3.8	-0.0	-1.9
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	3.6	1.9	-1.3
Pulse wave reflection index	1.6	2.0	3.6	1.9	-0.6
Loud music exposure frequency	1.6	1.8	3.1	1.8	-0.7
Medication: Ibuprofen	1.6	2.0	3.1	0.9	-1.8
Ovarian Cancer	1.5	2.0	3.8	0.5	-1.9
Blood Platelet Count	1.5	17.5	31.5	5.6	-1.9
Hearing difficulty/problems: Yes	1.5	2.3	4.6	0.3	2.1
Medication: Metformin	1.5	2.2	3.8	1.9	-0.7
Ever highly irritable/argumentative for 2 days	1.5	1.8	3.5	1.9	0.4
Osteoarthritis (self-reported)	1.5	1.9	2.6	1.2	-1.6
Financial situation satisfaction	1.5	1.9	2.2	1.5	-1.3
Neuroticism (Nagel 2018)	1.4	3.3	5.7	2.4	1.0
Financial difficulties in last 2 years	1.4	1.9	3.6	1.9	-0.4
Depression (self-reported)	1.4	1.7	3.2	-0.3	-1.8
Medication: Omeprazole	1.4	1.7	1.9	1.4	1.2
Heart disease (mother)	1.4	1.7	3.4	-1.8	0.3
Breast cancer (self-reported)	1.4	1.6	1.8	-1.2	1.4
Myopia	1.4	2.0	4.0	0.2	2.0
Schizophrenia (2018)	1.3	2.7	4.0	1.2	2.0
Heart attack	1.3	1.6	3.2	-1.8	-0.0
Qualifications: O levels/GCSEs or equivalent	1.3	2.0	3.0	1.7	-1.0
Worry too long after embarrassment	1.3	2.3	4.2	2.1	0.5
Mood swings	1.3	2.3	4.6	2.1	-0.3
Guilty feelings	1.3	1.9	3.6	0.5	1.9
Medication: Bendroflumethiazide	1.3	2.0	2.6	1.6	1.2
Heart attack/myocardial infarction (self-reported)	1.3	1.7	3.4	-1.8	0.2
Heart disease (siblings)	1.3	1.5	1.9	-1.4	1.1
Depressed Affect (Nagel 2018)	1.2	2.5	4.5	2.1	0.7
Major Depression (MDD)	1.2	1.4	2.9	0.1	1.7
Schizophrenia (2014)	1.2	2.6	4.9	0.6	2.2
Average weekly spirits intake	1.2	1.4	2.9	1.7	-0.1
Multivitamins +/- minerals	1.2	1.6	2.6	-0.7	1.6
Time employed in main current job	1.2	1.4	2.6	-0.5	1.6
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.6	2.7	0.6	-1.7
Mouth/teeth dental problems: Mouth ulcers	1.2	1.9	3.4	1.8	-0.7
Wears glasses or contact lenses	1.2	1.3	2.6	1.6	-0.3
Eye problems/disorders: Glaucoma	1.2	1.4	2.4	1.6	-0.6
Basal cell carcinoma (self-reported)	1.2	1.4	1.8	1.4	1.0
Worry (Nagel 2018)	1.1	2.4	4.7	2.2	0.2
Lung FVC	1.1	5.8	10.1	-3.2	1.2
Hair/balding pattern: Pattern 2	1.1	1.4	1.9	1.4	-1.0
Headache pain in last month	1.1	1.9	1.9	1.4	-1.3
Number of children fathered	1.1	1.3	2.5	0.2	1.6
Shortness of breath walking on level ground	1.1	1.3	1.6	-1.0	1.3
Bipolar Disorder or Schizophrenia	1.0	2.4	4.7	0.2	2.2
Schizophrenia vs Biploar Disorder	1.0	1.3	2.6	1.6	0.2
Crohns Disease (2012)	1.0	1.6	2.8	-1.7	0.7
Relative age of first facial hair	1.0	2.0	3.5	0.7	-1.9
Nervous feelings	1.0	1.8	3.6	1.9	-0.3
Qualifications: College or University degree	1.0	3.3	4.8	-2.2	1.4
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	2.0	-0.6	-1.4
Eye problems/disorders: Cataract	1.0	1.2	2.3	1.5	0.2
Medication: Gliclazide	1.0	1.2	2.2	1.5	-0.4
Supplements: Fish oil (including cod liver oil)	1.0	1.4	2.7	-0.1	1.6
Age started oral contraceptive pill	1.0	1.3	2.4	-0.5	1.5
Depression (Nagel 2018)	0.9	1.4	2.7	1.6	-0.2
Alzheimer’s Disease (in mother)	0.9	1.0	1.3	-1.2	0.9
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.5	1.6	-0.2
Illnesses of siblings	0.9	1.3	2.4	-0.5	-1.5
Worrier / anxious feelings	0.9	1.6	2.5	1.6	0.9
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	5.8	-2.4	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	5.9	-2.4	0.4
Illnesses of siblings: Diabetes	0.9	1.2	2.3	0.2	1.5
Verbal and Numeric Reasoning (VNR)	0.8	1.8	2.7	1.7	-0.9
Diabetes (mother)	0.8	1.0	1.3	1.1	-0.9
High blood pressure	0.8	2.2	2.3	1.5	1.4
Fluid intelligence score	0.8	1.7	2.4	1.0	-1.6
Father’s age at death	0.8	1.1	1.5	1.2	0.8
Falls in the last year	0.8	1.1	1.9	1.4	-0.4
Asthma	0.8	1.5	2.9	1.7	-0.3
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	1.8	0.4	-1.4
Forced vital capacity (FVC), Best measure	0.8	2.9	5.8	-2.4	0.0
Commuting to job workplace: Car/motor vehicle	0.8	0.9	1.8	1.3	0.1
Back pain experienced in last month	0.8	1.1	2.1	1.4	-0.5
High cholesterol (Self-reported)	0.8	1.5	2.8	1.7	-0.4
Risk taking	0.8	1.1	2.2	0.3	1.5
Ever had prostate specific antigen (PSA) test	0.8	0.9	1.2	-0.8	1.1
Pain experienced in last month	0.8	1.3	1.8	-1.3	1.0
Bipolar Disorder (2018)	0.7	1.1	1.1	-1.1	1.0
Ulcerative Colitis (UC)	0.7	1.2	1.3	-1.1	1.1
Prostate Cancer	0.7	1.0	1.2	0.9	1.1
Body Mass Index (BMI) (2010)	0.7	0.9	1.9	1.4	0.0
Ever had hysterectomy (womb removed)	0.7	0.7	0.8	0.9	-0.8
Medication: Co-codamol	0.7	0.8	1.3	-1.2	0.5
Diabetes (father)	0.7	0.9	1.5	1.2	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	2.9	-1.7	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.1	1.4	-0.4
Arm fat percentage (right)	0.7	2.9	4.3	2.1	-1.2
Medication: Lansoprazole	0.7	0.8	1.1	1.0	-0.7
Age at first live birth	0.7	1.2	2.5	-1.6	0.0
Eye problems/disorders: None of the above	0.7	0.9	1.7	-1.3	0.1
Leg fat mass (right)	0.7	2.7	4.1	2.0	-1.2
Suffer from ‘nerves’	0.7	1.1	1.5	1.2	0.8
Hypertension (Self-reported)	0.7	1.8	2.8	1.7	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	0.9	-1.0	-0.8
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.1	-1.0	0.7
Alzheimer’s Disease (in father)	0.6	0.7	1.3	-1.1	-0.2
Alzheimer’s Disease (including proxy)	0.6	0.9	1.6	-1.3	0.4
Rheumatoid Arthritis	0.6	0.8	0.9	0.9	-0.9
Cardiovascular Disease	0.6	2.0	3.7	1.9	0.6
Age when periods started (menarche)	0.6	1.5	3.0	-1.7	-0.3
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.3	-0.3	-1.1
High blood pressure (mother)	0.6	0.9	1.1	1.0	-0.8
Had other major operations	0.6	0.8	0.8	-0.9	0.9
Forced vital capacity (FVC)	0.6	2.4	4.7	-2.2	-0.5
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	1.4	-0.4	-1.2
Prospective memory result	0.6	0.7	1.4	-0.2	1.2
Chest pain or discomfort	0.6	0.9	1.6	0.5	-1.3
Arm fat percentage (left)	0.6	2.2	3.7	1.9	-0.9
Diabetes diagnosed by doctor	0.6	1.0	1.9	1.4	-0.4
Asthma (self-reported)	0.6	1.2	2.2	1.5	-0.3
Average weekly champagne plus white wine intake	0.6	0.8	1.2	-0.7	-1.1
Vascular/heart problems diagnosed by doctor	0.6	1.5	2.0	-1.0	-1.4
Leg fat mass (left)	0.6	2.4	3.5	1.9	-1.1
Intelligence (Savage-Jansen 2018)	0.5	1.4	2.3	1.5	-0.8
Fasting Glucose	0.5	0.6	0.9	-0.6	-0.9
Triglycerides	0.5	0.8	1.3	0.4	1.2
Systolic Blood Pressure	0.5	2.4	4.5	0.5	2.1
Systolic blood pressure, automated reading	0.5	1.4	1.5	1.1	1.2
Serious illness, injury or assault to yourself	0.5	0.6	1.1	0.5	-1.0
Diabetes (self-reported)	0.5	0.8	0.9	0.9	-0.9
Arm fat mass (right)	0.5	1.9	2.6	1.6	-1.0
Exposure to tobacco smoke at home	0.5	0.5	1.0	1.0	0.0
Gout (self-reported)	0.5	0.7	1.3	-0.2	1.1
Medication: Amlodipine	0.5	0.8	1.4	1.2	0.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.2	-1.1	0.0
Emphysema/chronic bronchitis	0.5	0.6	1.1	-1.1	0.3
Neck or shoulder pain in last month	0.5	0.7	1.2	1.1	-0.4
Supplements: Vitamin C	0.5	0.6	1.0	-1.0	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.1	0.0	1.1
Average weekly red wine intake	0.5	0.7	1.0	1.0	-0.6
Commuting to job workplace: Public transport	0.5	0.6	0.8	0.9	-0.7
Breast Cancer	0.4	0.9	1.3	-1.1	-0.7
Waist Hip Ratio (WHR)	0.4	1.7	2.5	0.9	-1.6
Lung FEV1/FVC ratio	0.4	2.2	2.9	-1.7	1.2
Number of treatments/medications taken	0.4	0.6	1.2	1.1	-0.2
Medication for hormone replacement therapy	0.4	0.5	0.6	-0.6	0.7
Supplements: Zinc	0.4	0.4	0.7	0.3	-0.8
Townsend deprivation index at recruitment	0.4	0.6	0.8	0.9	-0.7
Taking other prescription medications	0.4	0.6	0.8	0.6	0.9
Hearing difficulty/problems with background noise	0.4	0.6	0.6	0.8	0.8
Breastfed as a baby	0.4	0.5	0.9	-1.0	0.1
Tense / ‘highly strung’	0.4	0.7	1.0	1.0	-0.6
Peak expiratory flow (PEF)	0.4	0.9	1.2	-1.1	0.7
Body fat percentage	0.4	1.7	2.9	1.7	-0.7
Leg fat percentage (right)	0.4	1.4	2.5	1.6	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.1	1.0	-0.3
Medication: Seretide 50 evohaler	0.4	0.5	0.8	0.9	-0.4
Whole body fat mass	0.4	1.8	2.6	1.6	-1.0
Alcohol intake frequency.	0.4	1.0	2.0	0.1	-1.4
Overall health rating	0.4	1.0	1.2	1.1	-0.9
Had major operations	0.4	0.5	0.6	0.6	-0.8
Ever had bowel cancer screening	0.4	0.5	0.9	0.3	0.9
Illnesses of father: None of the above (group 1)	0.4	0.5	0.9	-0.9	0.5
Medication: Paracetamol	0.4	0.6	1.0	0.4	-1.0
Alcohol drinker status: Never	0.4	0.5	0.6	0.6	-0.8
Average weekly beer plus cider intake	0.4	0.6	0.8	-0.7	-0.9
Fractured/broken bones in last 5 years	0.4	0.5	0.7	-0.9	-0.6
Cholesterol lowering medication	0.4	0.6	0.6	0.8	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.8	-0.9	0.3
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.8	0.9	0.1
BMI	0.3	2.0	3.0	1.7	-1.0
Respiratory disease	0.3	0.7	0.7	0.8	-0.8
Leg fat-free mass (left)	0.3	1.6	1.9	1.1	-1.4
Trunk fat percentage	0.3	1.0	1.9	1.4	-0.4
Relative age voice broke	0.3	0.4	0.7	-0.9	0.4
Supplements: Glucosamine	0.3	0.4	0.8	-0.9	0.0
Body mass index (BMI)	0.3	1.5	2.2	1.5	-0.9
Impedance of leg (left)	0.3	1.3	2.3	-1.5	0.6
Leg predicted mass (left)	0.3	1.5	1.8	1.0	-1.4
Trunk fat mass	0.3	1.3	2.2	1.5	-0.6
Waist circumference	0.3	1.2	1.3	1.1	-1.1
Qualifications: None of the above	0.3	0.7	0.8	0.7	-0.9
Hair/balding pattern: Pattern 3	0.3	0.5	1.0	-0.1	1.0
Pulse rate	0.3	0.6	0.8	-0.9	0.5
Lung cancer (father)	0.3	0.4	0.8	0.9	-0.1
Hair/balding pattern: Pattern 4	0.3	0.7	0.8	-0.9	-0.8
Blood clot in the leg (DVT)	0.3	0.4	0.7	-0.9	-0.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.1	-0.1	-1.0
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.7	0.2	0.8
Comparative body size at age 10	0.3	0.7	1.1	0.6	-1.1
Health satisfaction	0.3	0.4	0.6	-0.8	-0.5
Medication: Allopurinol	0.3	0.4	0.6	0.7	0.4
Comparative height size at age 10	0.3	1.6	2.2	-1.0	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	0.5	-0.7	0.6
Arm fat mass (left)	0.3	1.3	1.9	1.4	-0.9
Miserableness	0.3	0.5	0.9	1.0	0.2
Leg fat percentage (left)	0.3	1.1	2.0	1.4	-0.5
Supplements: Calcium	0.3	0.3	0.6	0.8	0.0
Coronary Artery Disease (CAD)	0.2	0.2	0.5	-0.1	0.7
Mean Putamen Volume	0.2	0.2	0.4	0.2	0.6
HDL Cholesterol	0.2	0.3	0.7	0.8	-0.0
Neuroticism (2016)	0.2	0.2	0.4	0.7	0.2
Primary Biliary Cirrhosis	0.2	0.3	0.6	-0.8	0.2
Blood Eosinophil Count	0.2	1.4	2.8	0.3	-1.7
Allergy or Eczema	0.2	0.6	1.1	-1.1	0.0
Vitamin and mineral supplements	0.2	0.3	0.5	-0.2	-0.7
Severe depression (siblings)	0.2	0.2	0.4	0.6	-0.2
Pack years adult smoking proportion	0.2	0.3	0.3	-0.5	-0.6
Impedance of leg (right)	0.2	1.1	1.9	-1.4	0.6
Current tobacco smoking	0.2	0.4	0.6	-0.8	-0.4
Average weekly fortified wine intake	0.2	0.3	0.5	0.1	-0.7
Qualifications: CSEs or equivalent	0.2	0.3	0.5	0.7	0.2
Stomach or abdominal pain in last month	0.2	0.2	0.3	-0.2	-0.6
Alcohol usually taken with meals	0.2	0.3	0.4	-0.4	-0.6
Medication: Ramipril	0.2	0.2	0.2	-0.5	0.5
Medication: Simvastatin	0.2	0.3	0.5	0.3	-0.7
Weight	0.2	1.1	1.2	1.1	-1.0
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.9	0.1	-1.0
Mouth/teeth dental problems: Dentures	0.2	0.3	0.4	0.5	-0.6
Illnesses of mother	0.2	0.3	0.4	0.4	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.4	-0.6	0.5
Birth weight	0.2	0.3	0.4	-0.5	0.6
Exposure to tobacco smoke outside home	0.2	0.3	0.6	0.7	-0.1
Medication for pain relief, constipation, heartburn	0.2	0.4	0.6	-0.8	-0.3
Pulse rate, automated reading	0.2	0.5	1.0	-1.0	-0.0
Age at last live birth	0.2	0.4	0.6	-0.7	-0.4
Medication: Aspirin	0.2	0.2	0.4	0.2	0.7
Leg fat-free mass (right)	0.2	1.3	2.1	0.7	-1.4
Mineral and other dietary supplements	0.2	0.3	0.5	-0.3	-0.7
Leg predicted mass (right)	0.2	1.1	1.9	0.6	-1.4
Medication: Lisinopril	0.2	0.3	0.4	-0.6	0.4
Basal metabolic rate	0.2	0.9	1.6	0.4	-1.3
Pack years of smoking	0.2	0.3	0.4	-0.6	-0.4
Crohns Disease (2017)	0.1	0.3	0.5	0.7	0.2
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	-0.4	0.7
Bipolar Disorder (2011)	0.1	0.1	0.3	-0.2	0.5
Lupus	0.1	0.1	0.2	0.4	0.3
Heel T-Score	0.1	0.8	1.6	-0.3	-1.2
Smoking Status	0.1	0.2	0.4	-0.6	0.1
Hypothyroidism (self reported)	0.1	0.3	0.5	-0.1	-0.7
Chronotype (morning person)	0.1	0.3	0.5	-0.7	-0.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.2	-0.5	0.3
Angina	0.1	0.1	0.1	-0.3	0.4
Hand grip strength (right)	0.1	0.4	0.7	-0.9	-0.2
Medication: Atenolol	0.1	0.1	0.2	0.4	0.1
Medication: Levothyroxine sodium	0.1	0.1	0.3	0.1	0.5
Pain all over the body in last month	0.1	0.1	0.1	0.2	0.3
Trunk fat-free mass	0.1	0.3	0.5	-0.3	-0.7
Happiness	0.1	0.1	0.2	0.1	0.4
Noisy workplace	0.1	0.1	0.1	0.4	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.3	-0.5	0.2
Medication: Cholesterol lowering	0.1	0.1	0.2	-0.0	-0.5
Trunk predicted mass	0.1	0.3	0.5	-0.4	-0.7
Length of working week for main job	0.1	0.1	0.1	-0.4	-0.3
Birth weight of first child	0.1	0.2	0.3	-0.3	-0.6
High blood pressure (siblings)	0.1	0.1	0.1	0.3	0.3
Number of full brothers	0.1	0.1	0.2	-0.2	-0.5
Angina (self-reported)	0.1	0.1	0.2	-0.4	0.2
Number of full sisters	0.1	0.1	0.3	0.5	0.0
Family relationship satisfaction	0.1	0.1	0.1	-0.4	0.1
Leg pain on walking	0.1	0.1	0.2	-0.5	0.1
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.3	0.2	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.4	-0.6	-0.2
Whole body fat-free mass	0.1	0.5	1.1	0.2	-1.0
Long-standing illness, disability or infirmity	0.1	0.2	0.4	-0.6	-0.2
Friendships satisfaction	0.1	0.1	0.2	-0.4	0.4
Commuting to job workplace: Walk	0.1	0.1	0.2	0.4	-0.3
Medication for cholesterol	0.1	0.1	0.3	-0.5	-0.2
Medication: Aspirin	0.1	0.2	0.3	-0.0	0.6
Smoking status: Current	0.1	0.1	0.2	-0.4	-0.2
Whole body water mass	0.1	0.6	1.1	0.2	-1.1
Number of self-reported non-cancer illnesses	0.1	0.2	0.3	0.6	0.4
Mother’s age at death	0.1	0.2	0.3	-0.5	0.2
Medication: Blood pressure	0.1	0.2	0.4	0.6	0.0
Illnesses of father: High blood pressure	0.1	0.1	0.3	0.2	0.5
Ever smoked	0.1	0.1	0.2	-0.4	0.2
Arm fat-free mass (left)	0.1	0.3	0.5	-0.0	-0.7
Diastolic blood pressure, automated reading	0.1	0.3	0.4	0.7	-0.4
Impedance of whole body	0.1	0.3	0.4	-0.7	0.4
Blood Red Count	0.0	0.5	0.8	-0.4	0.9
Blood White Count	0.0	0.0	0.0	0.2	0.1
Height	0.0	0.2	0.4	0.6	0.1
Hair Pigment	0.0	0.5	0.8	-0.3	0.9
Tanning	0.0	0.1	0.1	0.4	0.3
Hand grip strength (left)	0.0	0.0	0.0	-0.2	-0.1
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.0	-0.0	0.2
Maternal smoking around birth	0.0	0.0	0.0	0.1	0.0
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.1	0.2	-0.4
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.1	-0.1	0.2
Sitting height	0.0	0.2	0.4	0.0	-0.7
Past tobacco smoking	0.0	0.0	0.0	0.0	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.0	0.1	-0.3	-0.0
Allergy	0.0	0.0	0.1	-0.2	0.2
Impedance of arm (right)	0.0	0.2	0.4	0.2	-0.6
Hip circumference	0.0	0.2	0.3	0.5	-0.2
Alcohol intake versus 10 years previously	0.0	0.0	0.1	0.3	-0.0
Impedance of arm (left)	0.0	0.0	0.0	0.1	0.1
Standing height	0.0	0.3	0.4	-0.6	-0.3
Medication: Paracetamol	0.0	0.1	0.1	-0.3	0.3
Hypothyroidism/myxoedema (self-reported)	0.0	0.0	0.0	0.1	0.2
Arm fat-free mass (right)	0.0	0.1	0.2	-0.3	-0.4
Migraine (self-reported)	0.0	0.0	0.0	-0.0	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.0	-0.2	0.0
Arm predicted mass (right)	0.0	0.1	0.1	-0.1	-0.4
Smoking status: Previous	0.0	0.1	0.1	-0.3	0.3
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.1	-0.3	-0.1
Osteoporosis (self-reported)	0.0	0.0	0.1	-0.2	0.0
Pain type(s) experienced in last month: Hip pain	0.0	0.1	0.1	-0.2	-0.2
Medication: Atorvastatin	0.0	0.0	0.0	-0.1	0.2
Number of operations (self-reported)	0.0	0.1	0.1	0.3	0.2
Irritability	0.0	0.1	0.2	0.4	0.1
Arm predicted mass (left)	0.0	0.2	0.3	0.0	-0.6

Hub : Genes

SYBU

Models

Trait associations