TWAS hub - SYMPK

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0840	0.0250	2.9e-05	0.043	0.034	0.043	0.040	0.042	5.8e-06	5.1e-05	5.7e-06	1.2e-05	6.5e-06
2	GTEx	Cells Transformed fibroblasts	0.1770	0.0450	6.9e-06	0.140	NA	0.099	NA	0.128	1.2e-10	NA	7.5e-08	NA	7.5e-10
3	GTEx	Nerve Tibial	0.1498	0.0476	8.9e-04	0.049	NA	0.083	NA	0.075	2.2e-04	NA	1.8e-06	NA	5.4e-06
4	GTEx	Testis	0.2200	0.0740	2.5e-03	0.210	NA	0.179	NA	0.200	1.1e-09	NA	2.3e-08	NA	2.9e-09
5	METSIM	Adipose	0.0476	0.0169	6.7e-04	0.026	0.007	0.007	0.009	0.014	8.1e-05	2.3e-02	2.6e-02	1.3e-02	2.9e-03
6	YFS	Blood	0.0663	0.0150	9.8e-10	0.012	0.031	0.027	0.032	0.028	7.3e-05	1.7e-10	2.0e-09	1.2e-10	1.2e-09
7	TCGA	Breast Invasive Carcinoma	0.0283	0.0142	2.9e-03	0.020	0.010	0.017	NA	0.021	4.0e-05	2.8e-03	1.5e-04	NA	3.5e-05
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0719	0.0334	1.1e-03	0.043	0.012	0.020	NA	0.034	1.2e-05	1.6e-02	2.3e-03	NA	9.4e-05
9	TCGA	Prostate Adenocarcinoma	0.0870	0.0366	2.0e-05	0.063	0.034	0.044	NA	0.048	3.3e-07	1.5e-04	1.8e-05	NA	8.7e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Blood Eosinophil Count	12.5	96.2	139.2	10.6	11.8	8.5	-10.5	11.5	-5.3	6.1	10.8	10.8
Osteoporosis (self-reported)	6.3	7.8	12.3	1.9	3.1	2.1	-3.2	2.8	-3.5	1.9	2.9	3.1
Pulse wave reflection index	5.8	7.2	10.6	2.5	2.8	2.2	-2.6	2.8	-1.9	3.3	3.0	2.7
Back pain experienced in last month	5.7	8.3	10.2	2.5	3.2	2.7	-3.2	3.2	-2.0	2.5	3.1	3.2
Asthma (self-reported)	5.7	11.3	17.5	-3.7	-4.0	-2.8	3.3	-4.2	0.9	-2.9	-3.8	-3.5
Lung FEV1/FVC ratio	4.8	24.4	49.3	4.4	7.0	2.5	-5.7	5.8	-1.4	2.6	6.0	5.9
Asthma	4.8	9.5	15.4	-3.5	-3.7	-2.6	2.9	-3.9	0.7	-2.6	-3.4	-3.1
Medication: Lansoprazole	4.8	5.4	6.7	2.5	2.5	2.3	-2.4	2.6	-0.5	2.4	2.4	2.5
Knee pain experienced in last month	4.6	7.1	10.0	-2.2	-3.2	-1.5	3.1	-3.0	3.1	-0.1	-3.2	-3.0
Pulse wave Arterial Stiffness index	4.2	4.9	7.0	2.5	2.2	1.8	-2.1	2.6	-1.5	2.6	2.2	2.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.2	5.1	7.7	1.5	2.7	1.8	-2.6	2.1	-1.9	2.0	2.8	2.5
Average weekly beer plus cider intake	4.2	6.1	12.5	-0.8	-2.9	-1.2	3.0	-1.7	3.5	-1.7	-3.2	-2.8
Respiratory disease	4.1	9.1	13.9	-3.1	-3.7	-2.2	3.2	-3.6	0.7	-2.6	-3.4	-3.3
Pulse wave peak to peak time	3.7	4.3	7.1	-2.3	-2.1	-1.7	1.9	-2.5	1.3	-2.7	-2.0	-1.9
Medication: Omeprazole	3.7	4.5	7.5	2.2	2.7	1.5	-2.4	2.5	-0.8	0.9	2.5	2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.6	4.2	8.3	2.7	2.0	2.9	-1.9	2.4	-0.3	1.0	1.8	2.1
Hearing difficulty/problems: Yes	3.5	5.3	12.2	-2.4	-1.9	-2.7	2.1	-2.2	1.1	-3.5	-1.9	-2.2
Breast cancer (self-reported)	3.5	4.1	7.5	2.7	2.2	2.2	-2.0	2.3	-0.2	0.5	2.3	2.2
Primary Biliary Cirrhosis	3.4	4.8	8.6	1.8	2.7	1.6	-2.5	2.3	-1.6	1.1	2.9	2.5
Diabetes (father)	3.4	4.2	6.4	-2.0	-1.8	-2.0	2.4	-1.9	0.9	-2.5	-2.1	-2.3
Wheeze or whistling in the chest in last year	3.4	6.1	9.0	-3.0	-2.9	-1.6	2.2	-3.0	1.7	-2.5	-2.5	-2.4
Supplements: Glucosamine	3.0	3.9	6.2	-2.1	-2.3	-1.9	1.8	-2.5	0.8	-1.9	-2.2	-1.9
Blood Red Count	2.9	27.7	33.9	-4.9	-4.9	-5.3	5.8	-5.7	4.0	-5.5	-5.4	-5.7
Noisy workplace	2.9	3.6	6.3	-2.5	-2.0	-1.8	1.8	-2.3	0.4	-1.5	-2.0	-1.9
Hearing aid user	2.7	3.1	4.2	-2.0	-1.6	-1.5	1.6	-1.7	2.0	-1.9	-1.5	-1.8
Medication: Omeprazole (e.g. Zanprol)	2.7	3.3	6.6	1.6	2.6	0.9	-2.0	2.1	-0.8	0.8	2.3	2.1
Triglycerides	2.6	4.2	6.6	-2.1	-2.4	-2.3	2.3	-2.0	0.0	-1.1	-2.6	-2.4
Medication: Ventolin 100micrograms inhaler	2.6	3.4	5.7	-2.1	-1.9	-1.1	1.8	-2.4	0.5	-2.3	-1.7	-1.9
Medication: Paracetamol	2.6	4.0	6.1	-2.2	-2.3	-1.3	2.2	-2.4	1.5	-0.0	-2.5	-2.2
Illnesses of father: Heart disease	2.5	3.5	6.8	2.6	1.8	2.2	-1.9	2.5	0.1	0.5	1.6	2.0
Medication: Paracetamol	2.4	4.0	6.4	-2.2	-2.4	-1.3	2.1	-2.5	1.5	-0.3	-2.5	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.4	2.9	4.6	0.9	2.1	1.4	-2.0	1.4	0.4	2.0	2.0	2.0
Wears glasses or contact lenses	2.4	2.8	4.5	0.6	2.1	0.3	-2.1	1.7	-2.1	1.1	1.9	2.0
Comparative body size at age 10	2.3	6.4	11.0	2.0	2.2	3.3	-2.4	2.2	-0.1	3.3	3.2	2.4
Alcohol intake versus 10 years previously	2.1	3.2	4.7	-1.7	-2.0	-2.1	1.9	-1.6	1.5	-0.8	-2.2	-1.9
Chronic bronchitis/emphysema (mother)	2.1	2.4	4.1	-2.0	-1.7	-1.8	1.4	-2.0	1.0	0.7	-1.3	-1.6
Pulse rate, automated reading	2.1	6.7	10.3	2.2	3.1	1.1	-2.6	3.0	-3.2	1.6	3.0	2.6
Mineral and other dietary supplements	2.1	2.8	6.1	2.5	1.6	1.6	-1.4	2.3	0.2	1.0	1.7	1.5
Reaction Time	2.0	3.8	7.1	-2.1	-1.8	-2.7	2.0	-2.2	0.6	-1.1	-2.3	-2.0
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	3.5	-1.3	-1.8	-1.7	1.7	-1.4	0.7	-0.5	-1.9	-1.7
Basal cell carcinoma (self-reported)	2.0	2.3	4.1	0.6	1.8	0.9	-1.9	1.3	-2.0	1.2	1.6	1.8
Major Depression (MDD)	1.9	2.3	6.3	-0.5	-1.6	-0.5	1.9	-1.2	2.5	-0.6	-1.8	-1.7
Diabetes (self-reported)	1.9	2.9	5.1	-0.9	-1.5	-2.1	1.8	-1.0	1.8	-2.3	-1.8	-1.8
Leg pain on walking	1.9	2.3	4.7	-2.2	-1.4	-1.4	1.4	-2.0	0.9	0.3	-1.7	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.1	3.2	-1.5	-1.6	-1.4	1.2	-1.8	1.7	-0.7	-1.6	-1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	4.0	2.0	1.4	1.7	-1.5	2.0	-0.8	1.0	1.6	1.5
Qualifications: None of the above	1.8	3.8	6.5	-1.3	-2.2	-1.1	2.5	-1.7	2.5	-0.9	-2.1	-2.4
Eye problems/disorders: None of the above	1.8	2.0	3.5	1.9	1.2	1.6	-1.2	1.7	-1.4	1.0	1.4	1.3
Commuting to job workplace: Car/motor vehicle	1.8	2.1	5.8	0.1	1.5	-0.3	-1.9	1.0	-2.4	1.1	1.5	1.6
Diabetes diagnosed by doctor	1.8	3.0	6.2	-0.5	-1.5	-1.7	1.8	-0.7	2.4	-2.5	-1.8	-1.7
Supplements: Calcium	1.8	2.0	4.5	1.2	1.6	1.0	-1.5	1.2	-2.1	1.0	1.2	1.6
HbA1C	1.7	1.9	3.5	-1.9	-1.2	-1.7	1.5	-1.4	0.4	-1.0	-1.4	-1.5
HDL Cholesterol	1.7	2.9	5.4	1.3	2.1	1.2	-2.1	1.9	-0.6	0.1	2.3	2.1
Systolic Blood Pressure	1.7	8.5	14.9	-3.9	-3.5	-3.1	3.0	-3.3	-0.1	-1.1	-2.8	-3.3
Hand grip strength (left)	1.7	4.4	8.4	2.4	1.9	2.9	-2.1	2.4	-0.4	1.5	2.3	2.1
Ever had bowel cancer screening	1.7	2.0	4.5	0.7	1.7	-0.4	-2.1	1.5	-1.2	0.7	1.4	2.0
Type 2 Diabetes (T2D) (2012)	1.6	1.8	7.5	0.0	0.0	0.0	0.0	0.0	0.0	-1.6	-2.7	-2.5
Hand grip strength (right)	1.6	4.5	9.7	2.7	1.6	3.1	-1.8	2.2	0.3	2.3	1.9	1.9
Relative age voice broke	1.6	2.5	3.3	-1.6	-1.3	-1.4	1.8	-1.4	1.4	-1.7	-1.6	-1.8
Glaucoma (self-reported)	1.6	1.9	6.4	-0.7	-1.3	-1.0	1.1	-1.2	2.5	-1.0	-1.7	-1.1
Handedness (chirality/laterality): Left-handed	1.6	2.0	4.9	-1.7	-1.2	-1.4	1.4	-1.2	0.6	-2.2	-0.9	-1.4
Commuting to job workplace: Public transport	1.6	2.0	2.9	-1.0	-1.7	-0.3	1.7	-1.5	1.1	-1.4	-1.7	-1.6
Neuroticism (2016)	1.5	2.2	3.7	1.9	1.5	1.6	-1.0	1.3	1.2	1.8	1.5	1.2
Ever had hysterectomy (womb removed)	1.5	1.7	3.9	-1.5	-1.3	-1.1	1.0	-1.3	2.0	-1.1	-1.2	-1.2
Qualifications: A levels/AS levels or equivalent	1.5	3.3	4.8	1.9	1.8	1.2	-2.1	1.8	-1.9	1.5	1.8	2.2
Friendships satisfaction	1.5	1.9	3.3	-0.4	-1.4	-0.6	1.8	-1.2	1.5	-1.3	-1.8	-1.7
Medication: Gliclazide	1.5	1.7	3.7	-1.4	-0.9	-1.8	1.2	-1.0	0.5	-1.9	-1.3	-1.2
Body Mass Index (BMI) (2010)	1.4	1.9	3.8	0.4	1.4	1.0	-1.6	1.2	-1.9	1.5	1.6	1.5
Type 2 Diabetes (T2D) (2018)	1.4	2.6	6.9	-0.8	-0.9	-2.5	1.4	-0.7	1.5	-2.6	-1.4	-1.4
Frequency of depressed mood in last 2 weeks	1.4	1.9	3.6	1.8	1.4	1.2	-1.4	1.9	-0.1	0.5	1.7	1.4
Medication: Metformin	1.4	1.9	5.5	-0.4	-1.1	-1.6	1.4	-0.4	1.5	-2.4	-1.4	-1.3
Age at first live birth	1.4	2.5	5.7	2.4	0.8	2.1	-1.3	1.5	1.4	1.6	0.9	1.5
Supplements: Vitamin C	1.4	1.6	2.8	-1.7	-1.4	-1.2	1.1	-1.5	0.7	-1.1	-1.4	-1.1
Illnesses of father: None of the above (group 1)	1.4	1.7	4.2	-1.4	-1.4	-1.0	1.3	-2.1	0.2	-0.6	-1.4	-1.3
Alcohol drinker status: Never	1.4	1.7	4.1	2.0	0.9	1.9	-0.9	1.5	0.2	1.0	0.9	1.1
Heart disease (siblings)	1.4	1.7	3.7	1.7	1.0	1.1	-1.1	1.9	-1.6	0.6	0.7	1.2
Blood Platelet Count	1.3	15.4	24.3	2.2	3.4	4.8	-4.9	3.2	-3.2	3.0	4.8	4.6
Waist circumference	1.3	4.8	10.9	-0.2	3.0	-0.0	-2.7	1.6	-2.3	1.5	3.3	2.4
Hair/balding pattern: Pattern 4	1.3	3.0	4.5	2.1	1.9	1.8	-1.9	2.0	0.2	0.9	1.8	2.0
Emphysema/chronic bronchitis	1.3	1.4	2.3	0.7	1.1	1.0	-1.4	1.2	-0.7	1.5	1.4	1.3
Family relationship satisfaction	1.3	1.6	2.8	-0.3	-1.5	-0.9	1.6	-1.0	1.5	-0.8	-1.7	-1.5
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	3.4	1.6	1.2	1.8	-1.4	1.4	-0.9	1.4	1.5	1.5
Depression (Nagel 2018)	1.2	1.8	3.6	1.9	1.2	1.4	-1.3	1.8	0.7	0.5	1.3	1.4
Prostate Cancer	1.2	1.7	3.3	1.2	1.4	1.6	-1.2	1.2	-0.7	1.0	1.8	1.2
Hayfever/allergic rhinitis (self-reported)	1.2	1.5	2.3	-1.3	-1.3	-0.5	1.3	-1.5	1.1	-1.4	-1.2	-1.3
Mean time to correctly identify matches	1.2	2.3	4.0	-1.7	-1.4	-2.0	1.6	-1.7	0.7	-0.8	-1.8	-1.6
Eye problems/disorders: Cataract	1.2	1.4	5.1	-2.2	-0.3	-1.6	0.3	-1.2	-0.8	-1.3	-0.3	-0.6
Average weekly champagne plus white wine intake	1.2	1.6	3.5	0.4	1.4	0.8	-1.9	0.8	-0.9	0.6	1.9	1.7
Mother’s age at death	1.2	1.4	2.3	-1.1	-1.1	-1.0	1.3	-1.4	0.7	-1.3	-1.5	-1.3
Illnesses of father: High blood pressure	1.2	1.5	2.5	0.7	1.4	0.5	-1.5	1.1	-1.6	0.9	1.4	1.4
Cholesterol lowering medication	1.2	1.7	8.9	-0.5	-0.6	-0.7	1.2	-0.5	1.5	-3.0	-0.6	-1.1
Alzheimer’s Disease (including proxy)	1.1	1.6	5.9	0.9	-1.5	0.1	1.5	-0.2	2.4	0.0	-0.8	-1.4
Relative age of first facial hair	1.1	2.2	3.4	-1.3	-1.4	-0.9	1.8	-1.4	1.1	-1.7	-1.9	-1.7
Medication: Co-codamol	1.1	1.3	2.4	-0.5	-1.4	-0.3	1.3	-1.0	1.6	-0.6	-1.4	-1.3
Average weekly fortified wine intake	1.1	1.3	3.2	0.0	1.6	0.2	-1.7	0.8	-0.8	-0.1	1.8	1.5
Pulse rate	1.1	1.9	2.8	1.5	1.6	0.9	-1.6	1.7	-1.0	0.3	1.5	1.6
Happiness	1.1	1.4	3.1	1.7	1.0	1.4	-1.0	1.8	-0.4	0.3	1.1	1.1
Illnesses of mother	1.1	1.3	6.0	1.1	0.9	0.8	-0.6	1.0	-1.0	2.4	0.6	0.7
Chest pain or discomfort	1.1	1.6	6.5	-1.1	-1.2	-1.1	0.7	-0.9	-0.5	-2.5	-1.3	-0.8
Had major operations	1.1	1.3	2.8	0.7	1.2	0.5	-1.3	1.0	-1.7	1.1	1.1	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	4.0	-1.7	-2.0	-1.5	1.3	-2.0	0.9	-0.1	-1.6	-1.3
Medication: Aspirin	1.1	1.4	2.9	-1.4	-1.0	-1.7	1.0	-1.0	0.8	-0.7	-1.4	-1.1
BMI	1.0	5.5	13.5	-0.6	3.3	-0.2	-3.1	1.4	-2.1	1.0	3.7	2.8
Systolic blood pressure, automated reading	1.0	2.8	7.3	-2.7	-1.8	-1.9	1.5	-1.9	-0.2	-0.7	-1.2	-1.8
High blood pressure (mother)	1.0	1.3	3.9	-2.0	-0.5	-0.8	-0.1	-1.1	-1.6	-1.9	-0.4	-0.1
Alcohol usually taken with meals	1.0	1.6	3.3	0.4	1.4	0.4	-1.8	0.7	-1.8	0.8	1.4	1.8
Worrier / anxious feelings	1.0	1.8	3.8	1.9	1.0	1.9	-1.5	1.5	0.5	0.7	0.8	1.6
Mouth/teeth dental problems: Dentures	1.0	1.7	2.8	-1.3	-1.2	-1.2	1.7	-1.3	1.1	-0.7	-1.4	-1.7
Loud music exposure frequency	1.0	1.1	2.2	-0.7	-1.1	-0.5	1.5	-1.0	0.1	-0.8	-1.5	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	1.8	-1.3	-0.9	-1.3	1.1	-0.9	-0.6	-1.3	-1.0	-1.2
Smoking status: Current	1.0	1.6	2.9	-1.7	-1.0	-1.3	1.4	-1.2	1.4	0.8	-0.8	-1.5
Eye problems/disorders: Glaucoma	1.0	1.1	4.5	-0.6	-0.5	-1.0	0.9	-0.8	2.1	-1.2	-0.9	-0.8
Medication: Atorvastatin	1.0	1.2	6.7	0.3	-0.2	-0.5	0.5	0.3	1.7	-2.6	0.2	-0.5
Fractured/broken bones in last 5 years	1.0	1.3	2.4	0.5	1.1	1.0	-1.4	0.9	-1.5	1.1	1.0	1.3
Ulcerative Colitis	0.9	1.4	3.6	-1.9	-0.5	-1.8	1.0	-1.3	0.4	-0.8	-0.7	-1.1
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.3	-1.5	-1.0	-1.2	0.9	-1.2	0.2	0.5	-1.1	-1.0
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.0	-1.2	-1.4	-0.4	0.9	-1.2	0.2	-1.0	-1.2	-0.9
Impedance of arm (left)	0.9	4.1	10.6	-0.5	-2.8	-1.0	2.5	-1.7	1.1	-1.0	-3.3	-2.4
Intelligence (Savage-Jansen 2018)	0.8	2.4	6.6	0.7	1.8	0.5	-1.8	1.4	-2.6	0.9	1.5	1.8
Lupus	0.8	1.2	2.2	-0.9	-1.3	-1.5	1.3	-0.9	0.2	0.5	-1.2	-1.3
Angina	0.8	1.1	5.6	-0.4	-0.4	-1.2	0.7	-0.3	2.4	-1.0	-0.5	-0.7
Current tobacco smoking	0.8	1.4	2.4	-1.5	-0.8	-1.3	1.3	-0.9	1.3	1.1	-0.6	-1.4
Hearing difficulty/problems with background noise	0.8	1.3	2.1	-0.8	-1.4	-0.5	1.1	-1.1	1.2	-1.5	-1.2	-1.1
Length of working week for main job	0.8	0.9	1.2	1.0	1.1	1.0	-0.8	1.0	-1.0	-0.2	1.1	0.8
Leg fat percentage (right)	0.8	2.8	7.2	-1.4	2.0	-0.9	-1.8	0.4	-2.7	0.6	2.4	1.5
Neck or shoulder pain in last month	0.8	1.1	2.1	0.6	1.1	0.7	-1.2	1.2	-1.4	-0.3	1.3	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	2.6	1.6	1.5	1.0	-1.3	1.4	0.3	0.7	1.5	1.5
Leg fat percentage (left)	0.8	2.9	6.8	-1.2	2.0	-0.8	-1.8	0.6	-2.6	0.9	2.5	1.5
Pack years of smoking	0.8	1.2	3.4	-1.8	-0.6	-1.0	1.1	-1.1	1.4	0.2	-0.6	-1.2
Ovarian Cancer	0.7	0.9	2.8	1.7	0.5	1.7	-0.3	1.2	-0.1	-0.2	0.6	0.4
Mean Putamen Volume	0.7	0.8	1.4	-0.4	-1.2	-0.1	1.2	-1.1	1.0	0.1	-1.0	-1.1
Lung FVC	0.7	3.4	7.8	0.8	-2.3	1.1	2.2	-1.0	2.8	-0.9	-2.1	-1.9
Pack years adult smoking proportion	0.7	1.0	3.6	-1.9	-0.6	-1.1	0.9	-1.0	0.9	0.2	-0.4	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	4.2	-2.0	-1.3	-1.0	0.7	-1.6	0.4	-1.4	-1.0	-0.9
Illnesses of siblings	0.7	1.0	3.2	-0.5	-0.9	-0.1	1.1	-1.2	1.8	0.8	-0.7	-1.0
Lung cancer (father)	0.7	0.8	2.8	-1.7	-0.7	-0.2	0.9	-1.2	-0.4	-0.5	-0.8	-1.0
Birth weight of first child	0.7	1.3	4.7	1.6	0.6	2.2	-0.5	0.9	1.3	0.5	0.7	0.6
Peak expiratory flow (PEF)	0.7	1.7	4.2	1.8	0.8	2.0	-1.5	1.2	-0.3	0.1	1.0	1.5
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.1	1.4	0.9	0.7	-1.3	1.1	-0.6	0.4	1.2	1.4
High blood pressure (siblings)	0.7	1.0	2.7	0.1	1.1	0.1	-1.2	0.8	-1.6	-0.8	1.1	1.1
Forced vital capacity (FVC), Best measure	0.7	2.6	6.8	0.3	-2.6	0.3	1.7	-1.5	2.2	-0.5	-2.0	-1.5
Medication for pain relief, constipation, heartburn	0.7	1.2	1.8	1.4	1.0	1.1	-1.2	1.1	-1.2	0.4	1.3	1.2
Medication: Seretide 50 evohaler	0.7	0.8	2.0	-0.4	-1.1	0.4	0.9	-0.8	1.4	-0.7	-0.9	-0.9
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.0	-1.4	-0.8	-1.2	0.6	-1.2	-0.5	-0.6	-1.1	-0.7
Age started oral contraceptive pill	0.7	0.9	3.0	-0.9	-0.7	-0.6	1.0	-1.0	1.7	0.4	-0.8	-0.9
Unable to work because of sickness or disability	0.7	0.9	1.7	0.8	1.3	0.6	-1.1	1.1	0.5	0.6	1.2	1.1
Leg fat mass (left)	0.7	2.6	6.4	-0.9	1.9	-0.3	-2.0	0.7	-2.1	0.6	2.5	1.7
Alzheimer’s Disease (in father)	0.6	0.6	2.1	0.1	-1.1	0.3	1.0	-0.1	1.4	-0.0	-0.7	-0.9
Breast Cancer	0.6	1.4	2.1	0.8	1.4	1.1	-1.4	1.0	-1.1	0.7	1.4	1.4
Diabetes (mother)	0.6	0.8	2.4	0.5	0.8	-0.0	-0.5	1.1	-1.5	-1.3	0.7	0.5
Severe depression (siblings)	0.6	0.7	1.4	-1.0	-0.8	0.4	0.7	-1.2	0.8	0.7	-0.5	-0.8
Age when periods started (menarche)	0.6	1.5	2.0	-1.3	-1.4	-0.7	1.4	-1.4	0.5	-1.4	-1.4	-1.4
Medication: Atenolol	0.6	0.7	1.6	-1.2	-0.4	-1.3	0.9	-0.9	0.0	-0.9	-0.3	-0.9
Body mass index (BMI)	0.6	2.7	7.1	-1.0	2.2	-0.7	-1.9	0.7	-1.9	0.5	2.7	1.6
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	1.3	-0.7	-1.2	-0.4	1.1	-0.9	0.3	-0.1	-1.2	-1.1
Arm fat mass (right)	0.6	2.4	5.1	-1.0	1.8	-1.0	-1.9	0.5	-2.2	0.3	2.3	1.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	1.9	-1.4	-0.8	-0.6	0.6	-1.2	-0.4	-0.1	-1.1	-0.7
Gout (self-reported)	0.6	0.8	2.5	-1.6	0.1	-1.1	0.0	-1.1	0.8	-1.3	-0.2	-0.1
Qualifications: College or University degree	0.6	1.9	4.3	1.7	0.7	1.5	-1.0	1.3	-2.1	1.6	0.8	1.0
Angina (self-reported)	0.6	0.8	4.8	-0.1	-0.3	-1.0	0.6	-0.1	2.2	-0.8	-0.4	-0.5
Leg fat mass (right)	0.6	2.3	5.4	-1.0	1.7	-0.4	-1.9	0.6	-2.2	0.4	2.3	1.5
Medication: Aspirin	0.6	0.8	1.7	-1.2	-0.7	-1.3	0.9	-0.6	0.4	-0.8	-1.0	-1.0
Illnesses of siblings: Diabetes	0.6	0.7	3.0	0.2	0.8	-0.5	-0.7	0.9	-0.8	-1.7	0.5	0.6
Qualifications: nursing, teaching	0.6	0.9	2.0	-0.6	-1.4	-1.0	0.9	-0.9	-0.4	-0.5	-1.4	-0.9
Commuting to job workplace: Walk	0.6	0.6	2.0	-1.1	-0.6	-0.5	0.5	-0.9	1.4	-0.4	-0.3	-0.5
Commuting to job workplace: Cycle	0.6	0.8	3.2	0.2	-0.9	0.8	0.9	-0.7	1.8	0.1	-0.7	-0.7
Impedance of whole body	0.6	3.2	9.0	-0.4	-2.6	-1.0	2.2	-1.5	0.3	-1.0	-3.0	-2.1
Arm predicted mass (left)	0.6	3.0	7.5	0.2	1.9	0.7	-2.5	1.2	-1.6	1.0	2.7	2.2
LDL Cholesterol	0.5	0.8	4.9	0.8	-0.3	0.4	0.1	0.6	1.1	-2.2	0.1	-0.1
Impedance of leg (right)	0.5	2.4	5.8	-0.9	-2.2	-1.1	1.6	-1.5	-0.6	-1.2	-2.4	-1.6
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.7	-0.2	-0.9	0.1	0.9	-0.3	1.3	-1.0	-0.6	-0.9
High blood pressure	0.5	1.3	5.1	-2.3	0.0	-1.8	-0.1	-0.8	-1.4	-0.9	0.3	-0.2
Multivitamins +/- minerals	0.5	0.7	2.6	-0.1	0.7	-0.3	-0.5	0.1	-1.4	1.6	0.6	0.5
Forced vital capacity (FVC)	0.5	1.7	4.7	0.8	-2.0	1.1	1.2	-0.9	2.2	-0.7	-1.2	-1.0
Pain all over the body in last month	0.5	0.5	1.2	1.1	0.7	0.7	-0.4	0.9	0.6	0.9	0.4	0.4
Impedance of arm (right)	0.5	2.1	6.2	0.0	-2.0	-0.4	1.9	-1.1	0.9	-0.6	-2.5	-1.7
Arm fat percentage (right)	0.5	1.8	4.6	-1.1	1.6	-1.1	-1.4	0.3	-2.1	0.4	1.9	1.1
Hip circumference	0.5	2.2	6.8	-0.7	1.3	-0.1	-1.7	0.5	-2.6	1.0	2.1	1.4
Father’s age at death	0.5	0.6	1.6	-1.1	-0.5	-0.9	0.1	-1.0	-0.6	-1.3	-0.5	-0.2
Exposure to tobacco smoke at home	0.5	0.5	2.4	-1.3	0.3	0.1	-0.1	-0.6	-0.5	-1.6	0.2	0.0
Body fat percentage	0.5	2.1	5.9	-1.5	1.4	-1.4	-1.4	0.1	-2.4	0.5	1.8	1.1
Medication: Ibuprofen	0.5	0.6	1.2	-0.9	-0.8	-0.3	1.1	-1.0	0.0	-0.3	-0.8	-1.1
Whole body fat mass	0.5	2.2	4.7	-1.1	1.6	-0.9	-1.8	0.5	-2.2	0.5	2.1	1.5
Alcohol intake frequency.	0.5	1.2	2.6	-0.8	-1.4	-0.6	1.3	-1.1	0.2	-1.0	-1.6	-1.3
Age at last live birth	0.5	0.7	2.0	1.3	-0.0	1.1	-0.2	0.5	1.4	1.1	0.2	0.4
Hypertension (Self-reported)	0.5	1.3	4.3	-2.1	0.0	-1.9	-0.2	-0.7	-1.7	-0.6	0.3	-0.2
Average weekly red wine intake	0.5	0.8	2.9	0.2	0.8	0.2	-1.1	0.1	-0.7	1.7	0.8	1.1
Mood swings	0.5	0.8	1.3	-1.1	-0.8	-1.2	0.8	-1.0	1.0	-0.4	-0.9	-0.8
Long-standing illness, disability or infirmity	0.5	0.8	1.9	-1.4	-0.2	-1.4	0.5	-0.9	0.7	-0.9	-0.8	-0.6
Arm fat mass (left)	0.5	2.1	4.7	-1.0	1.7	-0.9	-1.8	0.5	-2.1	0.3	2.2	1.4
Arm fat-free mass (left)	0.5	2.5	6.5	-0.0	1.7	0.6	-2.3	1.0	-1.5	0.8	2.5	2.0
Myopia	0.5	0.7	2.2	1.0	0.8	0.7	-0.7	0.9	0.1	1.5	0.5	0.8
Alcohol drinker status: Previous	0.5	0.6	2.3	0.8	0.3	1.0	-0.2	0.7	0.9	-1.5	0.3	0.2
Schizophrenia vs Biploar Disorder	0.4	0.5	1.5	0.8	0.1	1.2	0.2	0.1	-1.0	1.1	-0.1	-0.1
Alzheimer’s Disease (in mother)	0.4	0.4	1.9	0.2	-0.3	-0.6	0.6	0.0	1.4	-0.7	0.0	-0.6
Crohns Disease (2017)	0.4	0.9	6.4	-0.6	0.3	-2.5	0.1	-0.1	0.8	-0.5	-0.1	-0.2
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.6	0.1	1.3	0.1	-1.4	0.8	-1.6	-0.1	0.9	1.3
Blood White Count	0.4	2.9	6.2	0.9	2.5	0.4	-2.2	1.7	-0.3	1.5	2.1	2.1
Smoking Status	0.4	1.1	2.2	-0.9	-1.0	-1.1	1.1	-0.7	1.5	0.8	-0.8	-1.1
Cardiovascular Disease	0.4	1.2	2.6	-1.2	0.6	-1.6	-0.9	0.2	-1.4	-1.4	0.9	0.6
Medication for hormone replacement therapy	0.4	0.5	1.0	-0.3	-0.8	-0.2	0.9	-0.8	-0.3	0.2	-1.0	-0.8
Vitamin and mineral supplements	0.4	0.5	1.3	1.0	0.0	0.9	-0.0	0.6	1.1	-1.0	-0.0	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.5	-1.6	-0.9	-0.6	0.5	-1.1	0.3	-1.3	-0.8	-0.7
Hayfever, allergic rhinitis or eczema	0.4	0.8	3.3	0.0	0.8	0.7	-0.9	0.6	-1.8	-0.7	0.9	0.8
Trunk fat mass	0.4	1.7	4.2	-1.4	1.1	-1.3	-1.5	0.1	-2.1	0.3	1.6	1.1
Medication: Ramipril	0.4	0.5	2.2	1.5	0.0	0.6	0.1	1.0	0.2	0.9	-0.2	0.0
Weight	0.4	2.2	5.6	-0.8	1.6	-0.4	-1.9	0.6	-1.9	0.5	2.4	1.6
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	4.4	2.0	0.1	2.1	-0.6	0.7	1.4	-0.5	0.5	0.8
Medication: Cholesterol lowering	0.4	0.6	1.3	0.8	0.9	-0.2	-0.8	1.1	-0.0	-0.0	1.0	0.8
Prospective memory result	0.4	0.5	1.5	-1.2	-0.7	-0.6	0.6	-1.0	0.6	-0.0	-0.4	-0.7
Trunk predicted mass	0.4	2.0	4.7	0.3	1.4	0.8	-2.1	1.1	-1.2	0.6	2.2	1.9
Headache pain in last month	0.4	0.6	1.7	-1.3	-1.2	-0.5	0.4	-1.0	-0.6	-0.3	-0.5	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.1	-0.4	-0.9	-0.6	0.7	-0.6	0.4	-0.2	-1.1	-0.6
Migraine (self-reported)	0.4	0.5	2.5	0.1	-0.1	-0.3	-0.1	0.0	-1.4	1.6	-0.3	0.1
Number of full sisters	0.4	0.5	1.6	0.4	-0.7	-0.3	0.8	0.2	-0.1	-1.3	-0.9	-0.7
Arm fat percentage (left)	0.4	1.5	3.8	-1.5	1.2	-1.5	-1.0	-0.1	-1.9	0.1	1.4	0.7
Osteoarthritis (self-reported)	0.4	0.6	2.4	-1.6	-0.3	-1.0	0.1	-1.0	-0.1	-0.7	-0.4	-0.2
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.0	-0.2	0.7	-0.1	-0.6	0.5	-1.4	0.3	0.9	0.5
Basal metabolic rate	0.4	2.0	5.2	-0.0	1.5	0.4	-2.0	0.9	-1.3	0.7	2.3	1.8
Diastolic blood pressure, automated reading	0.4	1.3	5.1	-0.6	1.1	-0.2	-1.1	0.4	-2.3	1.2	1.3	0.8
Vascular/heart problems diagnosed by doctor	0.4	1.1	4.4	2.1	-0.1	1.9	0.1	0.6	1.1	0.6	-0.3	0.2
Depressed Affect (Nagel 2018)	0.3	0.6	2.6	-0.6	-0.6	-0.7	0.7	-0.7	1.6	0.1	-0.5	-0.6
Irritable Bowel Disease (IBD)	0.3	0.6	3.5	-0.6	1.0	-1.9	-0.4	0.1	0.4	-0.1	0.6	0.3
Schizophrenia (2014)	0.3	0.7	1.8	-0.1	-0.9	-0.9	0.9	-0.6	0.5	0.8	-1.4	-0.8
Waist Hip Ratio (WHR)	0.3	1.5	4.8	0.4	2.2	-0.7	-1.5	1.1	0.3	0.7	1.4	1.5
Tanning	0.3	4.0	5.5	-2.1	-2.0	-1.8	2.1	-2.4	1.8	-1.8	-1.8	-2.2
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.0	-0.3	0.9	-0.5	-1.0	0.3	0.1	-0.4	0.5	0.9
Trunk fat percentage	0.3	1.4	3.3	-1.8	0.6	-1.8	-0.8	-0.4	-1.8	0.1	1.0	0.5
Serious illness, injury or assault to yourself	0.3	0.4	1.3	-0.8	0.4	-0.6	-0.3	-0.5	1.1	-1.0	0.1	0.3
Chronic bronchitis/emphysema (father)	0.3	0.4	1.4	0.4	-0.9	0.2	0.6	0.1	0.5	0.2	-1.2	-0.5
Impedance of leg (left)	0.3	1.6	4.5	-0.2	-1.9	-0.6	1.4	-1.1	-0.6	-0.8	-2.1	-1.3
Had other major operations	0.3	0.4	2.9	0.2	-0.4	0.3	0.2	-0.4	1.7	0.4	-0.4	-0.1
Financial difficulties in last 2 years	0.3	0.4	2.5	0.0	-0.3	0.5	0.5	-0.5	1.6	0.0	-0.6	-0.4
Mouth/teeth dental problems	0.3	0.5	0.8	0.8	0.8	0.4	-0.8	0.9	-0.5	-0.4	0.9	0.8
Medication: Simvastatin	0.3	0.4	1.4	-0.1	-0.2	-1.1	0.6	-0.2	0.4	-1.2	-0.6	-0.4
Trunk fat-free mass	0.3	1.9	4.4	0.3	1.4	0.8	-2.0	1.0	-1.1	0.5	2.1	1.8
Time employed in main current job	0.3	0.3	0.7	0.1	0.8	-0.1	-0.7	0.5	0.5	0.4	0.8	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	1.1	0.2	0.8	-0.2	-0.9	0.6	-1.1	-0.5	0.7	0.8
Falls in the last year	0.3	0.4	0.8	-0.0	0.8	-0.5	-0.9	0.4	-0.2	0.6	0.4	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	3.0	1.5	-0.6	1.3	0.1	0.1	1.7	0.3	-0.4	0.2
Tense / ‘highly strung’	0.3	0.6	1.4	0.8	0.9	0.2	-0.5	0.8	1.2	-0.8	0.7	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.5	-0.5	-0.2	-0.2	0.7	-0.7	1.6	0.4	-0.6	-0.6
Blood clot in the leg (DVT)	0.3	0.4	2.6	0.1	0.1	-0.6	0.4	0.1	1.6	-0.4	-0.1	-0.3
Medication: Amlodipine	0.3	0.5	2.0	-0.5	0.5	-1.2	-0.2	0.2	-1.4	0.4	0.5	0.1
Arm fat-free mass (right)	0.3	1.8	4.5	-0.3	1.3	0.3	-2.0	0.7	-1.2	0.4	2.1	1.8
Exposure to tobacco smoke outside home	0.3	0.4	1.3	-0.8	-0.8	-0.0	0.2	-0.5	-0.1	-1.1	-0.7	-0.3
Number of children fathered	0.3	0.3	1.7	0.1	0.7	0.4	-0.5	0.3	-0.2	-0.1	1.3	0.4
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.1	0.7	0.1	1.1	-0.1	0.1	0.9	-0.7	-0.2	0.2
Medication: Blood pressure	0.3	0.4	2.5	-0.5	0.2	-0.8	-0.4	0.1	-1.6	0.6	0.1	0.3
Heart disease (mother)	0.3	0.4	1.2	-0.2	0.1	1.1	-0.6	0.1	0.4	-1.1	0.4	0.5
Arm predicted mass (right)	0.3	1.4	3.7	-0.4	1.1	0.3	-1.8	0.6	-1.1	0.4	1.9	1.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	1.3	0.4	-0.1	-0.2	0.2	0.5	-1.1	1.1	0.0	-0.2
Whole body fat-free mass	0.3	1.8	4.5	0.2	1.4	0.7	-2.0	1.0	-0.9	0.7	2.1	1.8
Leg fat-free mass (right)	0.3	1.5	3.7	0.4	1.3	0.8	-1.7	1.0	-0.4	0.8	1.9	1.6
Medication for cholesterol	0.3	0.4	1.1	-0.1	-0.7	-0.7	0.3	-0.6	1.0	0.8	-0.7	-0.3
Whole body water mass	0.3	1.9	4.8	0.3	1.4	0.8	-2.0	1.0	-1.0	0.7	2.2	1.8
Leg predicted mass (right)	0.3	1.4	3.6	0.4	1.3	0.7	-1.7	0.9	-0.4	0.8	1.9	1.5
Guilty feelings	0.3	0.4	0.7	0.4	0.6	0.6	-0.8	0.5	0.7	0.6	0.4	0.9
Ever taken oral contraceptive pill	0.3	0.4	2.6	0.5	-0.3	-0.0	0.3	0.1	0.3	1.6	-0.2	-0.2
Financial situation satisfaction	0.3	0.3	1.0	0.7	-0.4	0.1	0.8	0.1	0.1	0.4	-1.0	-0.6
Number of operations (self-reported)	0.3	0.5	2.5	-0.4	-0.2	-0.5	0.3	-0.5	1.6	1.0	-0.2	-0.3
Irritability	0.3	0.5	1.6	1.3	0.5	0.8	-0.3	0.7	0.9	-0.2	0.6	0.5
Risk taking	0.3	0.4	1.7	-0.8	0.1	-0.7	-0.1	-0.4	1.3	0.5	0.3	-0.0
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.0	1.0	-0.1	1.0	0.1	0.6	0.8	0.6	0.0	-0.0
Bipolar Disorder (2018)	0.2	0.2	1.1	0.7	-0.3	-0.4	0.1	0.4	-0.1	1.1	-0.3	-0.0
Bipolar Disorder or Schizophrenia	0.2	0.6	2.0	0.2	-0.6	-1.2	0.5	-0.2	-0.0	1.4	-0.9	-0.4
Neuroticism (Nagel 2018)	0.2	0.4	3.7	-0.1	0.1	-0.2	-0.1	-0.0	1.9	-0.1	0.0	0.2
Schizophrenia (2018)	0.2	0.5	1.7	-0.3	-0.5	-1.3	0.5	-0.5	0.1	1.0	-1.0	-0.4
Worry (Nagel 2018)	0.2	0.4	3.5	0.1	-0.1	-0.3	0.0	-0.1	1.9	-0.3	-0.3	0.0
Crohns Disease (2012)	0.2	0.3	1.4	-0.5	0.4	-1.2	0.3	0.1	0.8	-0.2	0.0	-0.3
Rheumatoid Arthritis	0.2	0.3	0.9	-0.6	0.5	-0.9	-0.4	0.1	-0.8	-0.4	0.4	0.3
Allergy or Eczema	0.2	0.5	2.6	-0.3	0.6	0.1	-0.5	0.1	-1.6	-1.0	0.7	0.4
Chronotype (morning person)	0.2	0.5	2.0	0.6	-1.1	0.5	0.4	-0.2	0.5	-1.4	-0.7	-0.4
Supplements: Zinc	0.2	0.3	1.2	0.4	-0.3	0.0	0.2	0.0	0.9	-1.1	-0.2	-0.1
Leg fat-free mass (left)	0.2	1.2	3.3	0.0	1.2	0.5	-1.6	0.7	-0.5	0.6	1.8	1.4
Townsend deprivation index at recruitment	0.2	0.3	0.8	0.9	0.2	0.9	0.4	0.8	-0.1	-0.3	0.1	-0.3
Taking other prescription medications	0.2	0.2	0.5	0.7	0.6	0.4	-0.3	0.5	-0.0	0.7	0.4	0.4
Qualifications: CSEs or equivalent	0.2	0.2	1.3	0.2	0.3	0.2	-0.5	0.2	-1.1	0.3	0.2	0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.4	-0.2	0.6	-0.1	-0.7	-0.0	-0.6	0.4	0.2	0.6
Sitting height	0.2	1.4	5.3	-0.2	-2.3	-0.8	0.9	-1.1	-0.3	-1.1	-1.5	-1.0
Leg predicted mass (left)	0.2	1.1	3.2	-0.0	1.1	0.4	-1.6	0.7	-0.5	0.7	1.8	1.4
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.9	0.6	0.9	-0.0	-0.6	0.7	0.4	0.1	0.6	0.6
Hair/balding pattern: Pattern 2	0.2	0.3	0.5	-0.7	-0.6	0.5	0.6	-0.6	0.1	0.3	-0.4	-0.5
Allergy	0.2	0.4	1.5	1.0	0.5	-0.0	-0.0	0.5	1.2	1.0	0.3	0.2
Hair/balding pattern: Pattern 3	0.2	0.3	0.8	-0.0	0.5	-0.3	-0.9	0.6	-0.6	-0.2	0.7	0.7
Breastfed as a baby	0.2	0.2	0.7	-0.3	-0.4	-0.5	0.3	-0.3	-0.3	-0.6	-0.8	-0.3
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.7	0.6	0.4	0.7	-0.3	0.4	0.2	0.8	0.1	0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.3	-0.1	-0.5	0.7	0.5	-0.7	1.1	0.3	-0.4	-0.4
Hypothyroidism/myxoedema (self-reported)	0.2	0.3	0.7	-0.8	-0.1	-0.7	0.5	-0.7	0.5	0.6	-0.2	-0.4
Number of full brothers	0.2	0.3	0.9	0.5	-0.7	-0.3	0.5	-0.0	0.4	-0.9	-0.7	-0.4
Health satisfaction	0.2	0.3	1.2	-0.4	-0.4	-0.7	0.1	-0.3	1.1	-0.1	-0.7	-0.2
Medication: Allopurinol	0.2	0.2	1.0	-0.6	0.1	-0.4	0.1	-0.4	1.0	-0.4	-0.1	-0.1
Overall health rating	0.2	0.5	1.2	0.4	0.8	-0.6	-0.8	1.1	-0.2	-0.3	0.6	0.8
Smoking status: Previous	0.2	0.3	1.1	1.1	-0.5	0.4	0.2	0.5	0.4	0.5	-0.6	-0.0
Number of self-reported non-cancer illnesses	0.2	0.3	0.7	-0.2	0.8	-0.4	-0.7	0.5	-0.0	-0.3	0.6	0.6
Medication: Blood pressure	0.2	0.3	1.2	-0.2	0.9	0.4	-0.4	0.5	-0.3	-0.1	1.1	0.3
High cholesterol (Self-reported)	0.2	0.4	2.9	0.1	0.2	-0.8	0.0	0.3	-0.1	-1.7	0.3	0.0
Medication: Lisinopril	0.2	0.2	1.1	-1.1	0.2	-0.6	-0.1	-0.1	-0.5	-0.5	0.3	-0.1
Pain experienced in last month	0.2	0.4	0.7	-0.3	-0.5	-0.7	0.7	-0.4	0.8	-0.5	-0.8	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.9	0.3	0.3	-0.6	0.3	0.3	1.4	-0.5	0.0	-0.2
Ulcerative Colitis (UC)	0.1	0.3	0.9	-0.1	0.9	-0.2	-0.6	0.2	0.2	0.3	0.7	0.6
Age at First Birth	0.1	0.2	0.6	-0.4	-0.3	-0.8	0.3	-0.3	0.3	-0.1	-0.6	-0.3
Fasting Glucose	0.1	0.2	0.7	-0.5	0.4	-0.8	0.0	-0.5	-0.4	0.2	-0.1	-0.0
Heel T-Score	0.1	0.6	2.3	0.0	-0.1	1.5	-1.0	0.4	-1.0	0.2	0.8	0.8
Hypothyroidism (self reported)	0.1	0.3	1.3	-0.7	0.1	0.1	0.2	-0.6	0.5	1.1	0.2	-0.2
Neuroticism	0.1	0.2	1.7	-0.3	-0.1	-0.3	0.1	-0.2	1.3	0.1	-0.2	-0.1
Hair Pigment	0.1	3.6	9.6	-3.1	-1.8	-2.1	1.3	-2.6	0.6	-1.1	-1.6	-1.6
Number of treatments/medications taken	0.1	0.1	0.7	-0.1	0.4	0.2	-0.2	0.2	-0.8	0.5	0.2	0.2
Average weekly spirits intake	0.1	0.1	0.5	-0.2	0.0	-0.1	0.7	-0.1	-0.1	-0.4	-0.1	-0.7
Sensitivity / hurt feelings	0.1	0.2	0.9	-0.5	0.1	0.5	-0.3	-0.2	0.9	0.3	-0.0	0.2
Maternal smoking around birth	0.1	0.1	0.4	-0.0	-0.5	0.4	0.1	-0.1	-0.6	0.2	-0.2	-0.1
Fed-up feelings	0.1	0.2	1.6	0.4	-0.1	-0.0	0.3	0.0	1.3	0.6	-0.1	-0.2
Stomach or abdominal pain in last month	0.1	0.1	0.5	-0.7	-0.1	-0.3	-0.1	-0.6	0.1	-0.3	0.0	0.1
Medication: Levothyroxine sodium	0.1	0.2	1.2	0.0	0.5	-0.0	-0.4	0.1	-0.4	1.1	0.3	0.4
Number of incorrect matches in round	0.1	0.2	0.6	0.0	0.4	0.4	-0.4	0.4	0.8	-0.0	0.3	0.4
Past tobacco smoking	0.1	0.3	1.4	-0.6	0.2	-0.1	0.0	-0.5	-0.4	-1.2	0.3	-0.1
Had menopause	0.1	0.1	0.8	-0.3	-0.2	0.0	-0.1	0.2	0.9	-0.6	0.1	-0.0
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	0.1	-0.1	0.4	-0.0	-0.2	0.4	-0.4	-0.3	0.1
Heart attack	0.1	0.1	0.3	0.2	0.6	-0.6	-0.3	0.4	0.0	0.3	0.4	0.3
Fluid intelligence score	0.1	0.3	0.7	-0.0	0.7	-0.0	-0.7	0.4	-0.8	-0.1	0.6	0.7
Neuroticism score	0.1	0.2	0.6	0.3	0.3	0.3	-0.3	0.3	0.8	0.6	0.1	0.4
Number of live births	0.1	0.2	0.7	-0.2	-0.7	0.3	0.4	-0.4	0.1	-0.2	-0.8	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	-0.6	-0.0	-0.3	-0.2	-0.3	-0.7	-0.2	-0.3	0.1
Depression (self-reported)	0.1	0.1	0.3	-0.3	0.3	-0.0	0.2	-0.1	0.6	-0.4	0.2	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.6	-0.5	0.4	-0.8	-0.1	-0.3	-0.4	0.4	0.1	0.1
Shortness of breath walking on level ground	0.1	0.2	0.6	-0.6	0.3	-0.6	-0.2	-0.0	-0.3	-0.7	0.3	0.1
Comparative height size at age 10	0.1	0.5	1.1	1.0	-0.2	1.0	-0.8	0.4	0.4	0.6	0.5	0.8
Suffer from ‘nerves’	0.1	0.2	0.9	-0.3	0.3	-0.9	-0.3	0.2	0.5	-0.3	0.4	0.2
Loneliness, isolation	0.1	0.2	0.5	0.1	-0.4	-0.0	0.7	-0.0	0.7	0.2	-0.2	-0.6
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.4	0.2	-0.1	-0.3	-0.3	0.4	-0.2	-0.6	0.4	0.2
Medication: Bendroflumethiazide	0.1	0.1	0.4	-0.6	0.3	-0.1	0.1	-0.2	-0.1	0.0	0.4	-0.2
Ever smoked	0.1	0.3	1.7	-0.2	0.2	-0.4	-0.3	0.3	-0.3	1.3	0.3	0.2
Ever depressed for a whole week	0.1	0.1	0.3	0.4	-0.2	-0.2	0.4	-0.1	0.4	-0.5	-0.5	-0.3
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.4	0.4	0.7	-0.4	-0.4	0.5	0.0	0.4	0.4	0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.2	0.5	0.3
Height	0.0	0.8	3.5	0.4	-1.9	1.2	0.4	-0.5	0.5	-0.5	-1.1	-0.5
Nervous feelings	0.0	0.1	0.2	0.2	0.3	0.3	-0.0	0.3	0.2	-0.4	-0.0	0.1
Standing height	0.0	0.3	2.0	0.5	-1.4	0.6	-0.1	-0.2	0.0	-0.2	-0.6	0.0
Birth weight	0.0	0.0	0.1	0.2	-0.0	0.3	0.1	-0.2	0.3	0.2	0.1	-0.0
Worry too long after embarrassment	0.0	0.1	0.3	0.2	-0.3	0.0	0.2	-0.3	0.3	-0.2	-0.6	-0.1
Miserableness	0.0	0.1	0.2	0.1	-0.1	0.4	-0.3	0.2	-0.3	0.5	-0.0	0.3

Hub : Genes

SYMPK

Models

Trait associations