Hub : Genes

SYT17

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Tibial 0.2087 0.0621 5.1e-04 0.000 NA 0.035 NA 0.010 3.3e-01 NA 9.6e-04 NA 5.2e-02
2 GTEx Lung 0.1799 0.0509 2.4e-05 -0.002 NA 0.046 NA 0.000 4.7e-01 NA 2.0e-04 NA 2.9e-01
3 GTEx Nerve Tibial 0.1858 0.0510 1.4e-04 -0.003 NA 0.053 NA 0.008 5.5e-01 NA 1.2e-04 NA 8.5e-02
4 GTEx Thyroid 0.3750 0.0620 4.5e-14 0.163 NA 0.313 NA 0.301 1.6e-12 NA 1.9e-24 NA 2.3e-23
5 METSIM Adipose 0.1121 0.0331 1.1e-05 0.029 0.030 0.031 NA 0.044 2.6e-05 1.9e-05 1.5e-05 NA 2.7e-07
6 YFS Blood 0.0617 0.0180 1.6e-07 0.029 0.030 0.039 0.037 0.038 6.6e-10 3.1e-10 1.1e-12 3e-12 1.5e-12
7 TCGA Kidney Renal Papillary Cell Carcinoma 0.1080 0.0440 3.3e-03 -0.004 0.030 0.013 NA -0.005 7.4e-01 7.5e-03 5.7e-02 NA 9.9e-01
8 TCGA Lung Squamous Cell Carcinoma 0.0567 0.0266 7.9e-03 -0.002 -0.001 -0.002 NA 0.000 8.7e-01 3.8e-01 8.1e-01 NA 3.6e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.8 1.5 0.3 0.6 -1.2 0.5 1.0 1.1 -1.0 0.8
Bipolar Disorder or Schizophrenia 0.4 0.9 2.2 -0.9 -1.5 0.7 0.2 1.0 1.5 0.2 -0.9
Depressed Affect (Nagel 2018) 0.6 1.2 4.9 -0.3 -1.2 1.3 -1.1 -0.7 -0.1 2.2 -0.2
Depression (Nagel 2018) 0.3 0.4 1.2 0.5 0.5 0.2 0.0 1.1 -0.1 1.1 0.6
Intelligence (Savage-Jansen 2018) 0.3 1.0 2.5 -1.6 0.4 -0.1 1.2 1.0 1.3 -0.9 -0.6
Neuroticism (Nagel 2018) 0.6 1.4 5.2 0.6 -1.5 2.3 -0.6 0.4 0.1 0.6 -1.6
Schizophrenia (2018) 1.0 2.0 5.1 -1.5 -2.3 2.0 -0.1 0.4 1.0 0.7 -1.8
Schizophrenia vs Biploar Disorder 0.7 0.9 3.1 -0.9 -0.6 0.7 1.7 -0.7 1.6 0.0 -0.1
Worry (Nagel 2018) 1.3 2.8 8.6 1.0 -1.0 2.9 -0.5 1.6 -0.7 -0.5 -2.9
Alzheimer’s Disease (in mother) 2.6 3.1 9.7 -1.9 -0.9 -1.2 -1.0 -0.7 -2.2 3.1 1.5
Alzheimer’s Disease (in father) 0.4 0.5 1.7 -0.3 -1.0 0.1 -0.1 0.7 1.3 -0.7 0.2
Alzheimer’s Disease (including proxy) 1.1 1.6 4.2 -1.8 -0.9 0.0 -0.1 -0.0 -2.0 2.1 0.4
Crohns Disease (2017) 0.3 0.6 2.7 0.1 -0.4 1.1 0.1 -0.6 -0.3 0.3 -1.6
Irritable Bowel Disease (IBD) 0.2 0.4 1.1 0.6 0.6 0.0 0.6 -0.8 -0.7 0.0 -1.1
Ulcerative Colitis (UC) 0.3 0.5 1.7 0.9 1.3 -0.9 0.4 -0.5 -0.7 -0.4 -0.1
Major Depression (MDD) 1.2 1.4 4.2 -1.0 -2.0 0.9 0.7 0.1 0.6 2.0 0.7
Reaction Time 0.4 0.8 4.1 -0.3 1.4 2.0 -0.1 -0.1 -0.5 0.3 -0.1
Verbal and Numeric Reasoning (VNR) 0.6 1.5 6.1 -0.8 0.7 -0.1 0.9 1.5 2.5 -0.8 0.9
Breast Cancer 1.1 2.8 9.0 -1.5 -3.0 -0.0 -2.4 -0.7 0.9 1.1 -1.7
Ovarian Cancer 1.1 1.5 4.0 1.0 1.0 1.5 2.0 1.7 -0.2 -1.0 -0.1
Prostate Cancer 0.6 0.9 4.3 -0.0 0.8 0.8 0.0 0.7 -0.7 -0.5 -2.1
Age at First Birth 1.7 2.5 6.9 -0.3 1.4 1.8 2.6 0.0 -1.0 -1.8 -2.0
Bipolar Disorder (2011) 0.2 0.2 0.7 -0.3 0.5 -0.2 0.3 0.9 0.5 0.0 0.0
Body Mass Index (BMI) (2010) 0.7 0.9 2.4 -1.3 -0.7 -1.5 -0.2 0.5 -1.4 0.4 -0.4
Coronary Artery Disease (CAD) 0.5 0.6 2.5 -0.1 -1.0 0.6 0.3 -0.9 0.4 1.6 0.0
Crohns Disease (2012) 0.4 0.6 2.0 -0.3 -0.7 0.7 -0.2 -1.4 0.6 0.0 -1.3
Mean Putamen Volume 0.6 0.7 1.5 -1.2 0.3 0.7 0.4 0.4 -1.0 0.8 -1.2
Fasting Glucose 2.7 3.2 9.2 -0.9 -1.5 -2.7 -3.0 -1.6 0.7 -0.7 1.4
HbA1C 0.8 0.9 3.0 -1.4 -0.7 0.3 -1.0 -0.0 -0.2 -1.7 -0.9
HDL Cholesterol 0.3 0.6 1.5 0.3 0.4 1.2 -0.7 -0.2 0.9 -1.2 -0.5
LDL Cholesterol 0.3 0.4 1.0 -1.0 -0.9 0.2 0.3 -1.0 -0.2 0.8 0.1
Lupus 1.5 2.3 10.2 1.0 -1.1 -0.9 -0.6 -0.1 2.2 0.5 3.2
Neuroticism (2016) 0.5 0.7 4.1 0.4 0.1 0.9 -0.3 -0.4 0.4 2.0 0.0
Primary Biliary Cirrhosis 0.7 1.0 3.9 -0.4 -1.1 -1.5 0.0 -2.0 -0.1 -0.4 0.0
Rheumatoid Arthritis 0.3 0.5 1.2 0.3 -1.1 0.1 -1.1 -0.1 0.9 0.7 -0.3
Schizophrenia (2014) 0.9 1.9 4.6 -0.9 -1.8 2.1 0.8 1.0 1.3 1.6 -1.0
Triglycerides 0.6 1.0 2.5 -0.9 -1.6 -1.1 -1.0 -0.8 -0.1 1.5 0.0
Type 2 Diabetes (T2D) (2012) 0.6 0.7 3.3 -0.9 -1.8 -1.1 -0.4 -0.5 0.3 -0.2 -0.3
Ulcerative Colitis 0.1 0.2 0.5 0.1 0.7 -0.5 0.5 0.1 -0.4 -0.5 0.1
Blood Eosinophil Count 0.7 5.5 14.1 0.2 -1.8 -1.8 0.1 1.9 3.8 3.0 3.3
Blood Platelet Count 0.3 3.2 16.1 1.8 1.4 4.0 1.3 0.8 -0.6 0.7 -1.1
Blood Red Count 0.1 1.1 2.6 -1.4 -0.6 0.1 1.0 -0.5 -1.6 0.9 -1.5
Blood White Count 0.1 0.7 2.1 0.6 -0.5 1.3 -0.8 0.9 -0.1 1.5 0.2
Heel T-Score 0.4 3.2 8.5 -1.2 -2.1 -2.9 1.1 2.5 1.4 -1.5 0.1
BMI 0.4 2.3 11.4 -1.3 -1.4 -3.4 -0.2 -0.2 0.1 0.3 1.8
Height 0.5 9.0 34.1 -0.5 2.7 4.5 0.3 0.6 -1.6 -2.7 -5.8
Waist Hip Ratio (WHR) 0.9 4.0 10.6 0.1 -2.3 0.3 -2.2 -3.3 1.3 2.8 1.5
Systolic Blood Pressure 0.5 2.7 8.2 -1.4 -2.2 0.3 -1.8 -2.9 -0.8 1.8 0.2
Smoking Status 0.8 1.9 5.4 1.3 1.7 1.8 -1.0 -1.0 0.1 2.3 0.1
Allergy or Eczema 0.4 1.0 4.7 0.3 0.1 0.9 1.5 -0.2 -2.2 -0.1 -0.5
Cardiovascular Disease 0.2 0.8 2.4 0.5 -1.6 -0.8 -0.6 -0.2 0.1 0.8 1.5
Hypothyroidism (self reported) 0.4 0.9 5.2 0.6 -0.3 -0.2 0.8 0.8 -2.3 0.5 -0.5
Respiratory disease 0.2 0.4 1.1 -0.4 -1.1 -0.5 -0.4 -1.0 -0.3 0.0 0.7
Type 2 Diabetes (T2D) (2018) 0.8 1.6 4.3 1.9 0.7 -0.1 2.1 -0.3 -0.5 -2.0 0.3
Lung FEV1/FVC ratio 1.0 5.0 14.1 3.1 2.0 3.8 1.6 0.5 -2.3 -0.2 -2.0
Lung FVC 0.4 2.1 5.9 -0.2 1.0 -0.1 -1.2 0.4 -2.4 -2.1 -2.0
Neuroticism 0.4 0.9 2.3 -0.8 -1.5 1.3 0.1 0.1 0.7 -0.0 -1.3
Chronotype (morning person) 0.6 1.4 2.4 -1.6 1.4 1.1 1.2 0.5 -1.0 -0.9 -1.4
Hair Pigment 0.0 0.5 1.8 0.8 -0.2 -0.6 -0.0 1.3 0.8 0.6 0.6
Tanning 0.2 2.1 7.7 -1.3 -0.4 -0.6 -2.8 -1.0 -0.4 -2.4 0.3
Hand grip strength (left) 1.2 3.2 9.2 -1.1 2.7 -2.1 3.0 -0.0 -0.8 -1.8 -0.1
Number of treatments/medications taken 1.3 2.4 7.4 -1.4 -2.7 0.6 -1.2 -2.2 1.3 0.9 0.4
Average weekly spirits intake 0.6 0.7 3.0 -0.4 -0.3 1.1 -0.7 0.7 -0.1 1.7 0.4
Sensitivity / hurt feelings 1.8 3.1 10.9 0.3 -0.2 2.6 3.3 -1.2 -0.9 -1.1 -1.8
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.2 1.1 0.8 0.1 -0.4 0.6 -0.0 1.5 1.1
Hearing difficulty/problems: Yes 0.4 0.6 2.0 0.9 -0.0 0.8 0.5 -1.4 -0.6 0.6 -0.0
Relative age of first facial hair 0.4 0.8 2.3 -1.5 -0.9 1.1 -0.4 -0.6 1.2 0.5 -0.5
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 3.0 -1.7 0.7 1.0 -1.0 -1.0 -0.3 0.3 -1.7
Ever used hormone-replacement therapy (HRT) 0.6 0.7 2.5 -1.3 -0.3 0.0 1.1 0.3 1.6 -0.4 -0.5
Ever had hysterectomy (womb removed) 1.6 1.8 8.8 -0.3 -1.1 -1.0 -0.8 -0.0 3.0 1.6 0.8
Systolic blood pressure, automated reading 0.9 2.5 7.2 -0.8 -1.8 0.7 -2.0 -2.7 -0.7 2.0 -0.0
Eye problems/disorders: Diabetes related eye disease 1.1 1.2 5.2 0.1 -0.6 -1.7 -2.3 -1.0 -0.1 0.3 0.5
Angina 0.2 0.2 1.3 -1.1 0.1 -0.1 0.0 0.5 -0.4 0.2 0.4
Medication for hormone replacement therapy 0.3 0.3 1.3 -0.0 0.3 -0.4 1.1 -0.8 -0.2 0.3 -0.4
Vitamin and mineral supplements 0.9 1.2 3.0 0.4 1.7 -1.6 -0.8 -0.2 1.7 0.7 0.5
Supplements: Zinc 1.1 1.2 3.0 -0.2 -1.3 1.4 1.1 -0.0 -1.2 -0.0 -1.7
Medication: Co-codamol 1.0 1.2 3.4 -1.6 -1.8 0.6 -0.7 -0.1 0.8 1.4 0.5
Medication: Metformin 0.5 0.6 2.5 0.4 -0.4 -1.6 0.9 -0.4 -0.5 -0.3 1.0
Diabetes (father) 0.6 0.8 3.0 1.1 1.7 -0.2 0.6 0.1 -0.2 -0.7 -0.9
Diabetes (mother) 0.9 1.2 4.8 -1.3 -0.7 -1.3 -0.3 -2.2 -0.5 -0.1 -0.6
Severe depression (siblings) 0.8 0.9 3.4 -0.2 0.5 1.6 0.3 1.1 -0.4 0.2 -1.9
Pack years adult smoking proportion 0.9 1.4 3.8 0.2 -1.5 -0.4 0.2 0.1 1.9 1.7 1.5
Impedance of leg (right) 0.7 3.5 7.5 2.7 -1.6 2.7 0.9 -0.0 1.6 2.7 0.4
Leg fat-free mass (left) 0.4 2.1 4.3 -1.9 1.8 -1.2 -0.2 0.4 -1.4 -2.1 -1.5
Trunk fat percentage 0.4 1.8 4.6 1.6 -0.8 0.8 -1.6 -0.6 0.6 2.1 1.6
Hand grip strength (right) 1.2 3.2 11.1 -1.3 2.2 -1.5 3.3 -0.9 -1.6 -1.2 -0.9
Townsend deprivation index at recruitment 0.6 0.8 2.9 -0.4 -1.1 0.5 -0.1 -0.3 -0.7 1.7 -1.0
Current tobacco smoking 0.4 0.7 2.8 -0.9 0.3 0.3 -1.2 -0.7 -0.1 1.7 -0.2
Average weekly fortified wine intake 1.7 1.9 6.7 -0.1 -1.2 -1.2 -0.9 -2.6 2.2 0.6 0.6
Maternal smoking around birth 0.6 0.9 2.3 1.2 -0.7 0.8 0.7 1.5 0.7 1.0 -0.2
Fed-up feelings 0.1 0.2 0.6 0.5 -0.3 0.6 -0.4 0.2 -0.1 0.8 -0.4
Frequency of unenthusiasm / disinterest in last 2 weeks 1.7 2.2 6.7 2.1 1.8 0.4 0.6 2.6 -1.4 0.6 0.5
Relative age voice broke 0.4 0.7 1.6 1.0 -0.1 0.8 1.2 0.1 1.2 0.4 0.7
Taking other prescription medications 0.6 0.9 2.6 -0.6 -0.0 0.8 0.2 -1.6 -0.6 1.4 1.1
Age when periods started (menarche) 0.8 2.0 11.0 0.9 -0.1 3.3 0.8 0.1 0.7 -0.8 -1.6
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 2.8 -0.5 -1.7 -0.8 -1.0 0.1 0.8 0.6 0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.9 2.0 4.3 -2.1 -1.2 1.1 0.2 0.8 2.0 0.5 -2.0
Tinnitus: Yes, but not now, but have in the past 1.2 1.3 4.2 -2.1 0.3 -0.7 -1.4 -0.0 1.3 1.1 -0.4
Qualifications: CSEs or equivalent 1.1 1.5 6.5 0.4 -0.3 0.9 2.6 1.8 -0.8 -0.1 -0.5
Serious illness, injury or assault to yourself 1.0 1.2 4.2 -1.8 -0.1 0.5 -0.7 -0.5 0.8 -2.1 -0.8
High blood pressure 0.4 1.0 4.5 0.1 -1.4 -1.0 -2.1 0.1 -0.4 0.0 0.4
Hayfever, allergic rhinitis or eczema 0.6 1.3 6.9 0.4 0.6 0.7 2.6 -0.1 -1.6 0.3 0.3
Multivitamins +/- minerals 1.1 1.4 6.8 -0.5 -2.6 0.7 0.6 1.1 -1.3 -0.4 -0.5
Stomach or abdominal pain in last month 1.1 1.4 4.2 0.6 -1.3 -0.5 -2.0 -2.0 0.7 0.3 -0.1
Supplements: Glucosamine 1.4 1.8 7.7 -2.8 -1.0 -0.2 -0.8 0.1 -1.4 -1.1 -1.4
Diverticular disease/diverticulitis (self-reported) 2.3 2.7 7.6 -1.0 -1.2 1.0 -2.8 -2.5 0.3 0.5 -1.9
Medication: Atenolol 0.3 0.4 1.1 -0.3 0.2 0.5 0.8 -0.9 0.2 -0.7 -1.1
Medication: Levothyroxine sodium 0.8 1.3 3.9 1.8 -0.1 2.0 0.2 0.5 -1.3 0.5 -1.0
Sitting height 0.7 5.3 22.6 -1.2 2.4 1.8 0.3 0.7 -1.8 -2.4 -4.8
Chronic bronchitis/emphysema (father) 0.8 0.9 2.4 0.7 -0.9 -1.6 -1.4 0.9 -0.2 0.4 0.8
High blood pressure (mother) 1.2 1.7 6.7 0.5 -2.6 0.6 0.0 -2.1 1.2 0.2 -0.5
Body mass index (BMI) 0.3 1.2 3.9 -0.6 0.3 -1.8 -1.2 0.0 0.1 0.9 2.0
Impedance of leg (left) 0.6 2.9 7.2 2.6 -1.4 2.7 0.8 -0.3 1.4 2.2 0.3
Leg predicted mass (left) 0.4 2.1 4.2 -1.9 1.8 -1.2 -0.2 0.4 -1.4 -2.1 -1.5
Trunk fat mass 0.2 0.7 2.1 0.8 -0.1 0.5 -1.4 -0.5 0.3 1.4 0.8
Waist circumference 0.4 1.5 5.3 -0.5 -0.4 -0.7 -2.3 -1.4 0.5 1.2 1.4
Number of incorrect matches in round 0.9 1.5 3.7 1.7 -1.1 -0.4 -0.6 -1.9 -0.4 1.7 0.5
Past tobacco smoking 1.3 2.4 6.2 -2.1 -2.5 -2.1 0.1 1.3 1.0 -1.1 0.8
Alcohol usually taken with meals 0.6 0.9 2.2 -1.1 0.3 -0.2 -0.6 -1.3 -1.0 -1.5 -1.1
Nervous feelings 1.2 2.3 11.0 1.5 -0.6 3.3 -0.4 0.7 0.3 0.7 -2.0
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.5 6.1 0.5 -0.9 1.1 -1.7 0.2 0.0 2.5 -0.4
Hearing difficulty/problems with background noise 0.4 0.6 1.2 1.1 -0.2 0.7 1.0 -1.1 -0.3 -0.2 0.8
Hair/balding pattern: Pattern 2 2.2 2.8 11.9 0.6 -2.1 -1.2 0.6 1.5 3.4 0.3 1.3
Had menopause 0.6 0.7 2.7 0.6 1.7 0.3 0.2 1.3 0.2 -0.8 -0.1
Had other major operations 0.4 0.5 1.6 -1.1 -0.4 -0.4 0.2 1.3 0.5 -0.1 -0.4
Forced vital capacity (FVC) 1.3 5.0 13.1 -0.8 2.7 1.5 0.3 0.3 -2.5 -3.3 -3.6
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.9 5.5 -2.0 -1.2 1.0 0.0 0.3 1.6 -0.8 -2.3
Ever unenthusiastic/disinterested for a whole week 1.0 1.3 4.0 -1.5 -2.0 -0.3 -1.2 -0.6 0.9 1.0 -0.2
Qualifications: None of the above 0.6 1.3 2.5 1.6 -0.6 -0.7 0.9 0.1 1.3 1.6 1.4
Financial difficulties in last 2 years 0.6 0.9 1.6 1.3 -0.2 -1.0 1.3 1.2 1.1 -0.0 0.3
Mouth/teeth dental problems 0.4 0.5 1.4 -0.0 0.3 -1.2 -0.5 0.9 -0.7 -1.1 0.3
Heart attack 0.8 1.0 2.2 -1.5 -0.5 0.9 -0.3 0.1 -1.2 1.2 -1.2
Allergy 0.3 0.7 3.7 -0.3 -0.5 -0.5 -1.9 0.1 1.1 0.1 -0.5
Pain all over the body in last month 0.3 0.3 1.2 -0.3 0.3 -0.8 -0.2 -0.1 1.1 -0.2 0.5
Diabetes (self-reported) 0.6 0.9 1.8 1.3 1.3 -1.1 0.1 -0.8 -0.8 -0.8 0.7
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 6.0 -0.4 0.0 0.0 2.4 -0.2 0.1 -1.2 0.5
Medication: Ramipril 0.5 0.7 2.9 0.5 -0.5 0.5 0.5 0.9 -1.7 0.6 -0.6
Medication: Simvastatin 1.2 1.8 4.0 1.1 -0.2 -1.3 0.1 -2.0 2.0 0.7 1.7
Fluid intelligence score 0.3 0.7 4.1 -0.0 0.7 2.0 0.3 0.8 0.6 -0.2 0.3
Illnesses of siblings 0.5 0.7 1.9 0.7 1.1 -0.4 0.7 0.6 -1.4 -0.9 -0.2
Neuroticism score 0.3 0.6 1.9 0.5 -0.9 1.4 0.5 0.4 0.8 0.4 -0.7
Weight 0.1 0.4 1.4 -0.7 1.2 -0.5 -1.0 -0.2 -0.5 -0.3 -0.2
Impedance of arm (right) 0.8 3.6 9.4 3.1 -2.1 2.3 -0.8 0.4 1.6 2.2 1.1
Arm fat percentage (right) 0.5 1.8 5.2 0.6 -0.7 -0.5 -1.9 -0.2 0.7 2.0 2.3
Trunk fat-free mass 0.5 3.1 7.0 -2.5 2.2 -1.3 0.3 0.2 -0.7 -2.6 -2.1
Hip circumference 0.1 0.3 1.1 0.1 1.0 -0.4 -0.6 -0.1 0.0 -0.7 0.3
Time employed in main current job 0.6 0.7 2.2 0.1 0.0 0.7 1.5 -1.1 0.7 -1.2 -0.1
Alcohol intake versus 10 years previously 1.1 1.7 5.5 1.0 0.6 1.2 0.3 1.6 -2.3 -1.0 -1.3
Father’s age at death 0.6 0.8 1.8 0.3 -0.2 0.8 -0.4 -1.3 -0.9 -1.1 -1.3
Worrier / anxious feelings 1.1 2.0 6.1 -0.2 0.8 1.7 0.7 0.8 -1.2 -2.0 -2.5
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.4 1.3 0.6 -0.3 1.1 -0.5 -0.5 0.1 0.8 0.4
Falls in the last year 0.7 0.9 2.8 -1.2 -1.7 -0.9 -0.7 -0.9 -0.0 -1.0 -0.1
Hair/balding pattern: Pattern 3 1.4 2.1 6.8 -1.4 -0.4 0.1 -2.2 -2.6 -1.3 1.0 -0.4
Number of live births 0.6 0.9 1.9 0.4 1.1 -0.9 -0.6 1.3 -0.5 -1.4 0.9
Forced expiratory volume in 1-second (FEV1) 1.4 4.6 9.8 -0.0 3.0 1.3 0.6 -0.1 -2.8 -3.1 -3.0
Pulse rate 0.1 0.2 1.1 0.7 -0.2 1.0 0.2 0.1 0.2 0.3 -0.4
Happiness 0.4 0.5 3.1 1.8 0.6 0.4 -0.1 -0.2 -0.6 0.6 0.1
Noisy workplace 0.1 0.1 0.6 0.6 0.1 0.2 0.2 0.3 0.7 0.1 -0.0
Qualifications: A levels/AS levels or equivalent 1.0 2.1 7.6 -2.8 -0.2 -0.7 0.0 0.3 -0.5 -2.2 -1.9
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 0.9 0.9 -0.7 0.6 0.4 1.0 0.4 0.7 0.3
Mouth/teeth dental problems: Dentures 0.8 1.4 3.9 -1.1 0.1 -0.5 -0.5 -1.3 2.0 0.6 1.9
Asthma 0.6 1.2 2.8 -1.6 -1.7 1.0 0.6 -1.1 -0.2 0.8 1.0
Medication: Ibuprofen (e.g. Nurofen) 0.9 1.1 5.1 -0.6 0.1 -0.2 2.3 0.8 1.1 -1.3 -0.2
Medication: Cholesterol lowering 0.5 0.8 2.5 0.9 0.3 -1.1 0.5 -0.7 0.4 -0.7 1.6
Depression (self-reported) 0.2 0.3 1.0 0.1 -0.7 0.3 -0.2 1.0 -0.1 0.7 0.3
Medication: Lansoprazole 0.3 0.3 1.8 0.4 0.5 -0.2 -1.3 -0.6 0.1 -0.1 0.1
Prospective memory result 0.6 0.8 3.3 -0.7 -0.5 -0.5 -0.9 -1.0 -0.5 0.3 -1.8
Lung cancer (father) 0.9 1.0 2.7 -1.0 -0.7 -1.0 -0.9 -1.2 -0.8 1.6 0.3
Illnesses of mother 0.5 0.6 1.3 0.7 1.1 -0.3 0.3 0.4 0.9 -0.7 1.1
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.0 11.0 -0.1 3.3 1.6 1.3 -0.3 -2.6 -3.0 -2.9
Pulse wave Arterial Stiffness index 0.8 0.9 2.7 1.3 1.6 1.3 0.6 0.4 0.1 0.7 0.3
Impedance of arm (left) 0.7 3.2 8.7 3.0 -2.2 2.8 -0.4 0.4 0.9 1.7 0.5
Arm fat mass (right) 0.2 0.7 2.1 -0.1 -0.0 -0.8 -1.4 -0.2 0.3 0.9 1.3
Trunk predicted mass 0.6 3.2 7.3 -2.5 2.1 -1.2 0.3 0.3 -0.7 -2.7 -2.3
Standing height 0.5 4.9 20.2 -0.3 2.1 2.4 0.5 -0.3 -1.1 -2.7 -4.5
Length of working week for main job 0.7 0.7 2.2 -0.1 -1.5 -1.0 -0.2 1.4 -0.4 -0.1 0.7
Exposure to tobacco smoke at home 2.2 2.5 5.0 -0.7 -2.2 -2.2 -2.0 0.3 1.9 0.6 1.2
Breastfed as a baby 1.1 1.4 3.5 -0.9 1.6 0.8 -0.4 -1.1 -1.4 -0.3 -1.9
Tense / ‘highly strung’ 1.2 2.0 8.1 1.2 0.4 2.2 0.4 0.9 0.1 0.7 -2.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 1.9 0.7 -0.3 0.0 -1.2 0.9 1.4 0.5 -0.2
Hair/balding pattern: Pattern 4 0.6 1.5 3.5 1.5 1.6 0.0 1.3 1.9 0.4 -1.4 0.0
Birth weight of first child 1.2 2.1 4.6 0.0 -2.1 -1.9 0.1 0.8 1.9 -1.9 0.8
Peak expiratory flow (PEF) 1.7 4.0 11.4 1.0 3.4 2.2 1.5 0.4 -2.3 -2.1 -1.7
Pulse wave reflection index 0.7 0.9 2.4 1.6 1.4 0.2 0.0 -0.2 0.9 0.1 1.4
Ever highly irritable/argumentative for 2 days 0.9 1.0 4.5 -0.7 -2.1 0.7 0.4 0.6 1.0 1.2 -0.1
Loud music exposure frequency 1.1 1.2 2.3 1.0 1.3 -1.4 0.8 1.5 -0.1 0.4 1.3
Qualifications: O levels/GCSEs or equivalent 1.3 2.0 5.8 -1.5 0.3 0.9 -1.3 -0.2 -2.4 -1.1 -2.1
Mouth/teeth dental problems: Bleeding gums 0.2 0.2 0.7 0.4 -0.7 0.5 0.3 0.1 -0.2 0.9 0.1
Blood clot in the leg (DVT) 0.9 1.2 3.4 -0.0 1.3 -1.8 -0.1 1.0 -0.8 -1.6 0.1
Medication: Paracetamol 0.4 0.7 1.7 -0.7 -0.6 0.7 1.2 0.3 1.3 -1.0 -0.4
Headache pain in last month 0.7 1.2 4.0 1.5 -0.2 2.0 -0.1 0.2 -1.0 -0.1 -1.4
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 2.8 -1.7 -0.2 -0.8 -0.7 -0.1 1.2 0.5 0.4
Glaucoma (self-reported) 1.4 1.7 5.0 0.5 1.1 2.2 1.3 -0.4 -1.8 -0.3 -1.4
Gout (self-reported) 0.6 0.9 2.5 -1.1 0.8 1.6 -0.4 -1.1 -0.9 -0.5 -0.6
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 2.6 0.5 -0.3 0.3 0.3 0.1 -1.6 0.6 0.1
Medication: Amlodipine 0.3 0.4 1.3 0.1 -0.3 1.1 0.3 -0.5 0.5 0.5 -0.9
Medication: Ventolin 100micrograms inhaler 1.1 1.4 3.3 -1.8 -1.8 0.2 -0.9 -1.3 0.8 1.2 0.4
Birth weight 0.7 1.5 4.8 2.2 1.2 1.8 0.5 -0.5 -0.3 0.2 -1.5
Chronic bronchitis/emphysema (mother) 0.6 0.7 1.6 -0.8 0.0 -1.0 -1.2 0.9 -0.4 1.3 -0.3
High blood pressure (siblings) 1.2 1.7 4.4 -0.4 -1.7 -0.7 -0.9 -1.6 2.1 1.4 0.4
Forced vital capacity (FVC), Best measure 1.1 4.1 9.0 -0.7 2.8 1.3 0.9 -0.2 -2.1 -3.0 -2.9
Body fat percentage 0.5 2.1 6.3 1.4 -0.8 0.3 -1.6 -0.4 0.8 2.5 2.1
Leg fat percentage (right) 0.7 2.4 8.7 0.9 -0.5 -0.2 -1.1 -0.4 1.1 2.9 2.7
Arm fat-free mass (right) 0.6 3.1 6.1 -2.5 2.2 -1.2 0.8 0.2 -1.1 -2.2 -2.3
Exposure to tobacco smoke outside home 0.4 0.5 1.1 0.1 -0.7 0.6 0.8 -1.0 0.3 1.0 0.4
Comparative body size at age 10 1.2 3.4 13.0 -3.6 -1.2 -3.2 0.2 -0.7 -0.6 1.0 0.7
Number of full brothers 0.6 0.8 2.0 -0.9 -1.4 -0.1 0.4 0.9 1.3 1.0 -0.0
Worry too long after embarrassment 0.2 0.4 1.7 -0.3 -0.8 -0.2 0.3 0.4 0.7 -0.4 1.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 1.2 -0.0 -1.0 0.3 0.9 -0.8 -0.8 1.1 -0.7
Wheeze or whistling in the chest in last year 2.2 3.9 11.1 -1.8 -3.3 1.0 -1.5 -1.4 1.6 2.9 0.6
Number of children fathered 0.6 0.7 2.7 -1.6 -0.6 0.0 -0.2 -0.2 1.6 -0.3 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.7 0.0 0.7 -0.9 1.3 -0.8 0.9 -0.7 1.0
Age at first live birth 1.0 1.8 3.3 0.4 -1.5 1.7 1.8 -0.6 -0.7 -1.4 -1.7
Pulse wave peak to peak time 0.8 0.9 1.9 -1.4 -1.4 -1.3 -0.7 -0.4 -0.1 -1.0 -0.6
Health satisfaction 0.5 0.7 1.8 1.4 -0.2 0.7 -1.2 -0.9 0.2 0.9 0.0
Shortness of breath walking on level ground 0.9 1.0 2.3 1.5 -0.3 0.6 0.3 1.3 0.9 1.5 0.8
Qualifications: College or University degree 0.8 2.6 8.3 -2.9 -0.3 -1.0 -0.5 -1.3 -1.4 -2.4 -1.4
Eye problems/disorders: None of the above 1.3 1.5 3.9 0.8 -0.2 -2.0 1.4 0.4 0.6 1.8 1.3
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.2 -0.9 -1.1 0.1 0.7 0.6 -1.0 1.0 -0.3
Emphysema/chronic bronchitis 1.1 1.2 2.4 0.7 -0.0 1.5 1.1 1.5 0.8 1.6 0.4
Medication for pain relief, constipation, heartburn 0.9 1.6 4.0 2.0 -0.1 -0.6 -1.0 0.3 -1.9 1.7 1.0
Neck or shoulder pain in last month 1.6 2.3 5.0 -0.9 1.2 2.2 0.7 1.5 -0.4 -2.1 -1.9
Medication: Blood pressure 0.1 0.2 0.6 0.6 -0.0 0.4 0.0 0.8 -0.5 -0.5 -0.4
Angina (self-reported) 0.2 0.2 1.3 -1.1 0.1 -0.2 0.1 0.3 -0.5 0.3 0.2
Migraine (self-reported) 0.9 1.1 3.9 1.6 -1.1 0.9 -2.0 -0.3 -0.2 0.1 -0.8
Medication: Ibuprofen 1.0 1.2 7.0 -0.1 0.3 0.0 2.6 0.8 0.6 -1.1 -0.1
Medication: Allopurinol 0.9 1.3 4.3 -0.7 1.0 -1.2 -0.5 -0.7 -0.2 -2.1 1.5
Medication: Omeprazole 1.1 1.3 4.8 -0.2 -0.6 -0.8 -1.6 -0.6 0.3 1.1 2.2
Medication: Seretide 50 evohaler 0.4 0.4 1.0 -1.0 -0.0 0.6 -0.4 -0.2 -0.6 1.0 0.7
Mean time to correctly identify matches 0.4 0.7 3.0 -0.0 0.9 1.7 -0.9 -0.7 -0.6 0.0 -0.6
Heart disease (mother) 0.2 0.2 0.6 0.8 0.3 0.5 -0.5 0.2 0.0 -0.8 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 3.2 0.5 1.3 0.1 1.8 0.7 0.8 0.2 1.7
Whole body fat mass 0.2 0.8 2.4 0.5 0.0 -0.1 -1.5 -0.7 0.1 1.5 1.0
Leg fat mass (right) 0.2 0.7 2.7 0.0 0.1 -0.6 -1.0 -0.1 0.4 1.6 1.3
Arm predicted mass (right) 0.6 3.1 6.9 -2.6 2.1 -1.1 0.6 -0.3 -1.3 -2.0 -2.5
Pulse rate, automated reading 0.1 0.5 1.3 0.9 0.0 -0.4 -0.8 0.4 1.1 -0.4 -0.5
Alcohol intake frequency. 1.2 2.9 8.8 0.7 0.9 1.4 2.5 3.0 -1.9 1.2 -0.2
Comparative height size at age 10 0.4 2.4 8.3 -1.4 1.3 0.3 -1.3 -0.4 -1.5 -1.6 -2.9
Number of full sisters 0.5 0.6 2.1 -1.1 -0.2 -0.7 -1.4 -0.2 -0.0 0.6 0.5
Suffer from ‘nerves’ 1.1 1.7 5.3 1.1 -0.8 1.9 -0.4 1.5 -0.3 0.6 -2.3
Overall health rating 0.8 1.7 5.7 0.1 -0.4 0.3 -2.1 -2.4 0.3 1.1 1.5
Chest pain or discomfort 0.7 1.0 3.1 -0.8 -1.6 1.8 0.4 0.0 0.1 1.0 -0.4
Had major operations 1.3 1.5 4.9 -0.8 2.2 1.3 -0.2 1.5 -0.9 -0.3 -1.4
Age at last live birth 0.8 1.2 3.6 0.1 -0.9 1.9 1.7 0.5 -0.1 -0.7 -1.3
Family relationship satisfaction 1.1 1.4 4.0 -0.5 -1.3 -0.3 -0.9 0.9 0.1 2.0 1.8
Leg pain on walking 0.7 0.8 2.6 0.7 -0.2 0.4 1.4 1.6 1.0 -0.4 -0.4
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.2 0.6 0.4 1.1 -1.5 -0.3 -0.5 -0.3 -0.0
Commuting to job workplace: Car/motor vehicle 0.9 1.0 4.2 0.9 0.3 -0.6 1.1 -0.3 0.2 1.1 2.0
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 1.6 -0.9 -0.4 -0.5 -1.0 -1.3 0.4 0.3 0.8
Medication: Aspirin 0.7 0.9 4.8 -0.5 0.1 -0.4 0.7 -0.1 0.8 -2.2 -0.8
Supplements: Vitamin C 1.4 1.6 4.6 -0.7 -0.4 1.9 0.9 -2.1 -1.5 -0.1 -1.2
Knee pain experienced in last month 0.5 0.7 2.3 -1.3 -0.0 -0.9 -1.5 -0.9 0.0 0.1 0.4
Hypertension (Self-reported) 0.4 1.1 5.0 0.1 -1.1 -1.0 -2.2 -0.2 -0.8 0.0 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.6 1.9 9.9 0.5 -1.6 0.1 -0.5 -1.1 3.1 0.5 1.1
Illnesses of father: Heart disease 0.3 0.5 2.3 -1.5 0.7 -0.4 0.4 0.4 -0.4 0.0 -0.5
Illnesses of siblings: Diabetes 0.3 0.4 1.1 -0.1 -0.9 -0.1 -1.1 0.6 0.6 0.5 0.4
Smoking status: Previous 1.2 1.8 5.2 2.3 2.0 2.0 0.3 -0.8 -0.2 0.7 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.4 1.8 0.6 1.3 0.0 0.3 -0.3 -0.8 -0.1 -0.4
Whole body fat-free mass 0.5 2.9 6.2 -2.3 2.2 -1.2 0.3 0.4 -1.0 -2.5 -2.0
Leg fat-free mass (right) 0.5 2.7 6.2 -2.0 2.1 -1.3 -0.2 0.3 -1.6 -2.5 -1.6
Arm fat percentage (left) 0.4 1.7 4.8 0.5 -0.8 -0.5 -1.9 -0.3 0.4 1.9 2.2
Average weekly red wine intake 0.5 0.8 2.9 0.6 0.2 -0.2 -1.2 -1.1 -0.1 -1.7 -0.3
Handedness (chirality/laterality): Left-handed 0.8 1.0 5.6 0.1 -0.8 -0.2 0.7 0.5 2.4 -0.9 0.2
Mood swings 0.8 1.4 7.4 1.0 0.3 2.7 0.8 -0.0 -0.2 0.7 -1.1
Loneliness, isolation 0.8 1.1 5.3 -0.5 -1.5 0.3 -0.4 0.7 -0.3 2.3 0.1
Long-standing illness, disability or infirmity 0.4 0.7 2.1 -0.3 -1.1 -0.0 -1.5 -1.0 -0.2 -0.1 0.9
Ever had bowel cancer screening 1.6 1.9 6.0 -0.2 1.2 1.2 0.1 -0.9 -1.3 -1.8 -2.4
Diabetes diagnosed by doctor 0.5 0.8 2.2 1.5 0.8 -0.9 0.1 -0.5 -0.4 -1.4 0.4
Ever had stillbirth, spontaneous miscarriage or termination 3.4 3.7 8.8 0.2 1.6 -1.9 1.3 2.5 1.8 -3.0 1.8
Friendships satisfaction 0.4 0.5 2.6 0.3 -0.0 0.5 -0.0 1.6 -0.7 0.5 0.4
Qualifications: nursing, teaching 1.3 2.1 8.3 -0.7 0.4 2.1 -1.2 0.5 -0.3 -1.3 -2.9
Commuting to job workplace: Walk 1.1 1.2 3.1 -0.8 -1.5 1.7 -0.4 -0.9 0.5 0.0 -1.8
Eye problems/disorders: Cataract 1.9 2.2 5.5 -2.3 0.1 1.8 -1.9 -1.5 0.3 -0.5 -1.7
Mouth/teeth dental problems: Mouth ulcers 0.3 0.6 1.9 0.3 -0.1 1.0 -0.6 -0.6 1.4 0.3 -0.8
Medication for cholesterol 1.3 1.9 5.0 0.1 2.0 0.3 1.2 2.2 -0.2 -2.0 -1.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.6 1.9 5.2 -1.7 -2.3 -0.3 0.6 -1.4 0.6 2.0 -0.7
Back pain experienced in last month 0.3 0.4 1.7 -0.6 -0.9 0.4 0.1 1.3 -0.7 0.0 -0.2
Mineral and other dietary supplements 1.0 1.4 3.9 1.4 0.6 -0.2 0.1 0.7 2.0 1.6 1.3
Breast cancer (self-reported) 0.4 0.5 1.3 -0.6 0.1 -0.9 -0.1 -0.7 -0.3 -1.1 1.1
Asthma (self-reported) 0.6 1.2 3.0 -1.7 -1.7 1.1 0.5 -1.2 -0.3 0.7 0.7
Osteoporosis (self-reported) 1.2 1.5 3.2 -0.6 1.5 1.7 0.2 1.1 -1.8 -0.8 -1.1
Osteoarthritis (self-reported) 1.3 1.7 8.6 -0.6 -0.9 -1.1 -2.9 -0.6 0.7 -0.3 1.2
Medication: Aspirin 0.5 0.6 3.1 -0.4 -0.2 0.0 0.3 -0.5 0.9 -1.8 -0.8
Medication: Gliclazide 1.2 1.4 3.9 0.8 1.5 2.0 -0.6 0.2 -1.5 0.8 -1.0
Illnesses of father: None of the above (group 1) 1.5 1.9 3.8 1.8 1.6 1.8 1.9 -0.6 -1.1 -0.6 -0.1
Smoking status: Current 0.4 0.6 2.8 -0.8 0.6 0.1 -0.9 -0.5 -0.3 1.7 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.3 2.8 6.2 0.2 2.2 1.3 -0.5 -0.4 -2.2 -2.2 -2.5
Whole body water mass 0.5 2.7 5.7 -2.4 2.0 -1.3 0.2 0.3 -1.0 -2.4 -1.9
Leg predicted mass (right) 0.5 2.5 5.8 -1.9 2.1 -1.2 -0.2 0.3 -1.5 -2.4 -1.6
Arm fat mass (left) 0.2 0.8 2.6 -0.1 -0.2 -0.8 -1.6 -0.3 0.3 1.1 1.4
Number of self-reported non-cancer illnesses 0.9 1.5 4.5 -0.1 -1.3 -0.2 -1.7 -2.1 0.1 1.1 1.3
Average weekly champagne plus white wine intake 1.4 1.9 5.9 -1.0 1.1 1.0 0.1 -2.4 -1.2 -0.3 -2.1
Miserableness 0.5 0.8 3.4 0.9 -0.4 1.0 -0.2 -0.7 -0.7 1.9 -0.5
Guilty feelings 0.6 0.9 3.1 1.0 -1.8 0.4 0.9 0.1 1.1 0.7 0.4
Wears glasses or contact lenses 0.6 0.7 1.9 -0.8 0.4 -0.6 -1.4 -0.5 1.2 -1.0 -0.0
Ever taken oral contraceptive pill 0.7 0.8 2.4 0.1 -0.8 -1.3 -0.6 -1.6 -0.7 0.0 -0.9
Hearing aid user 0.3 0.3 0.9 0.5 -0.3 -0.2 -0.1 0.8 -0.9 0.6 -0.1
Mother’s age at death 1.0 1.3 4.4 0.5 -0.0 1.0 0.3 -1.6 -0.4 -1.3 -2.1
Financial situation satisfaction 0.4 0.4 2.2 0.1 -1.5 -0.5 -0.3 0.1 -0.2 0.8 0.5
Tinnitus: Yes, now most or all of the time 0.4 0.5 1.2 0.9 0.0 -0.1 0.8 0.8 0.7 -1.1 0.7
Commuting to job workplace: Public transport 0.4 0.4 1.3 0.9 0.2 0.1 -0.0 0.6 -0.3 -1.2 -0.9
Eye problems/disorders: Glaucoma 0.7 0.8 4.2 0.9 0.5 2.1 0.3 -0.2 -0.5 -0.4 -0.6
Medication: Blood pressure 1.3 2.4 8.3 -0.6 -2.0 -0.5 -2.9 -1.7 -0.3 1.4 1.2
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.7 0.2 0.5 0.6 -0.1 0.2 -0.8 0.8 0.5
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.6 0.2 -0.4 0.1 1.1 -0.4 -1.5 -1.6 -0.8
High cholesterol (Self-reported) 1.4 2.5 7.3 1.2 -1.3 -1.8 0.4 -1.1 2.2 -0.1 2.7
Medication: Bendroflumethiazide 0.6 0.9 2.7 1.3 -0.2 -0.8 -1.3 -0.3 -0.1 0.0 1.7
Medication: Paracetamol 0.4 0.6 1.9 -0.7 -1.2 0.4 0.6 -0.2 1.4 -0.5 -0.3
Medication: Lisinopril 1.1 1.5 5.2 -0.1 1.2 -1.6 -1.5 -0.7 0.1 -0.3 2.3
Medication: Atorvastatin 0.7 0.8 2.9 -0.9 -1.7 -0.8 1.1 0.7 0.2 -0.8 0.2
Illnesses of father: High blood pressure 1.7 2.1 7.5 -2.2 -2.7 -0.5 -1.0 1.7 0.1 -0.1 -0.9
Alcohol drinker status: Never 0.8 1.0 4.3 0.4 -0.5 1.3 0.7 0.2 0.7 2.1 -0.5
Ever smoked 1.5 2.6 5.4 2.3 2.3 2.2 0.2 -1.1 -1.7 0.7 -0.7
Basal metabolic rate 0.3 1.9 4.2 -2.1 1.8 -1.1 -0.0 0.2 -0.9 -1.9 -1.4
Leg fat percentage (left) 0.5 1.9 6.2 0.7 -0.5 -0.5 -1.1 -0.4 1.0 2.4 2.5
Arm fat-free mass (left) 0.4 2.2 5.6 -2.4 1.9 -1.0 0.4 0.1 -0.7 -1.9 -1.8
Number of operations (self-reported) 0.5 0.7 2.0 -1.4 -0.1 0.2 0.8 1.1 0.0 0.0 -1.3
Average weekly beer plus cider intake 0.4 0.5 1.1 -1.0 0.1 0.6 0.3 0.9 1.1 0.2 0.7
Irritability 0.8 1.3 3.2 -0.5 0.4 1.3 -1.4 -0.5 -1.3 -1.1 -1.8
Risk taking 0.7 1.1 6.1 -0.3 -0.6 0.6 0.4 -0.6 -2.5 0.8 -0.7
Ever had prostate specific antigen (PSA) test 2.5 2.8 9.5 2.0 -0.3 3.1 0.0 -0.7 -1.4 -0.8 -2.5
Fractured/broken bones in last 5 years 0.8 1.0 3.7 0.4 -0.8 -0.7 1.9 1.5 0.2 0.3 0.7
Age started oral contraceptive pill 1.8 2.3 5.2 0.8 -1.0 1.9 -2.3 -1.3 -0.9 0.6 -2.1
Diastolic blood pressure, automated reading 0.9 2.7 6.1 -1.0 -1.8 -0.7 -2.5 -2.0 -0.8 2.4 0.7
Ever depressed for a whole week 0.9 1.1 3.7 -0.3 -1.3 -0.9 -0.7 -0.9 0.8 1.9 0.3
Unable to work because of sickness or disability 0.3 0.3 1.0 -0.1 -0.4 0.7 -0.5 -0.6 -1.0 0.7 0.2
Commuting to job workplace: Cycle 0.8 0.9 2.7 0.0 -0.4 -1.2 -1.6 1.0 1.1 -0.9 -0.1
Myopia 0.5 0.7 2.6 -0.6 -1.0 0.1 0.5 -1.6 0.6 0.5 -0.8
Vascular/heart problems diagnosed by doctor 0.4 1.1 3.8 0.9 1.8 0.5 2.0 0.1 0.4 0.1 -0.2
Cholesterol lowering medication 0.7 1.0 2.6 -0.0 -1.5 -1.3 0.3 -0.1 1.6 0.8 0.8
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 2.4 0.2 0.3 -0.3 -1.3 -0.0 0.2 0.8 1.5
Pain experienced in last month 0.5 0.9 1.6 0.0 -0.1 -1.0 -0.9 -1.2 1.3 1.1 1.0
Supplements: Calcium 1.6 1.8 4.1 0.0 1.1 1.8 1.8 -1.3 -2.0 0.5 -0.7
Basal cell carcinoma (self-reported) 0.7 0.8 2.3 -0.7 0.4 -0.6 0.9 -0.1 1.5 1.2 0.8
Heart attack/myocardial infarction (self-reported) 0.7 1.0 2.2 -1.5 -0.8 0.8 -0.4 0.4 -1.3 1.1 -1.2
Deep venous thrombosis (DVT) (self-reported) 1.1 1.5 3.7 -0.2 1.5 -1.9 0.2 1.1 -1.1 -1.8 0.2
Heart disease (siblings) 0.6 0.7 4.3 -0.8 0.3 0.7 2.1 0.4 -0.1 -0.5 0.1
Alcohol drinker status: Previous 0.3 0.4 1.2 -0.3 -0.2 -0.0 0.4 0.9 -0.5 1.1 0.7
Pack years of smoking 0.8 1.1 3.2 0.0 -1.4 0.1 -0.2 -0.2 1.8 1.7 1.0
Impedance of whole body 0.7 3.8 11.4 3.4 -2.0 2.8 0.2 0.0 1.3 2.1 0.6
Leg fat mass (left) 0.1 0.6 1.4 -0.1 0.2 -0.7 -1.1 -0.1 0.3 1.2 1.1
Arm predicted mass (left) 0.4 2.0 5.1 -2.2 1.6 -1.4 0.3 0.2 -0.4 -1.9 -1.7