TWAS hub - TAC4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0132	0.0088	0.0087	0.007	0.010	0.002	NA	0.009	0.0096	0.0031	0.09	NA	0.0051
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0312	0.0166	0.0041	0.020	0.011	0.004	NA	0.000	0.0020	0.0200	0.11	NA	0.3100

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Lansoprazole	4.7	5.3	8.5	1.5	2.9
Pain experienced in last month	3.5	5.8	10.4	-1.1	-3.2
Leg pain on walking	3.4	4.2	7.0	2.7	1.2
Schizophrenia vs Biploar Disorder	3.2	4.2	5.2	-2.3	-1.8
Migraine (self-reported)	3.2	3.9	6.1	-2.5	-1.3
Qualifications: O levels/GCSEs or equivalent	3.1	5.0	7.1	2.7	1.7
Eye problems/disorders: Cataract	2.9	3.3	4.0	2.0	1.6
Friendships satisfaction	2.8	3.5	6.1	0.9	2.5
Wears glasses or contact lenses	2.8	3.2	5.8	-0.8	-2.4
Chronic bronchitis/emphysema (father)	2.7	3.2	5.1	-2.2	-1.1
Mean time to correctly identify matches	2.7	5.1	9.3	0.9	3.0
Average weekly beer plus cider intake	2.6	3.7	7.3	0.4	2.7
Reaction Time	2.4	4.6	8.6	0.7	2.9
Heel bone mineral density (BMD) T-score, automated (left)	2.4	5.3	10.7	0.2	3.3
Body Mass Index (BMI) (2010)	2.2	2.9	3.7	1.5	1.9
Schizophrenia (2014)	2.2	5.0	7.9	-2.8	-1.4
Comparative body size at age 10	2.2	6.1	9.6	1.6	3.1
Fractured/broken bones in last 5 years	2.2	2.9	4.4	2.1	1.2
Primary Biliary Cirrhosis	2.1	3.0	3.6	-1.6	-1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	2.1	2.8	5.0	-2.2	-0.8
Medication for hormone replacement therapy	2.0	2.2	3.2	1.1	1.8
Lung cancer (father)	2.0	2.4	4.6	0.4	-2.1
Hair/balding pattern: Pattern 4	2.0	4.9	5.5	-2.3	-2.1
Medication: Aspirin	2.0	2.7	3.8	2.0	1.2
Allergy or Eczema	1.9	5.0	9.9	-3.1	0.4
Lung FEV1/FVC ratio	1.9	9.8	13.5	3.7	2.5
Multivitamins +/- minerals	1.9	2.5	3.1	-1.7	-1.4
Fluid intelligence score	1.9	3.9	4.9	2.2	1.7
Breast cancer (self-reported)	1.9	2.2	3.5	-1.9	-1.0
Qualifications: None of the above	1.8	3.8	7.1	-2.7	-0.7
Depression (self-reported)	1.8	2.1	4.1	-2.0	-0.3
Supplements: Vitamin C	1.8	2.1	3.5	-0.9	1.9
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	2.9	-1.2	-1.7
Respiratory disease	1.7	3.7	7.1	-2.7	-0.6
Number of treatments/medications taken	1.7	3.1	3.3	-1.7	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	4.4	-2.1	-0.2
Pain all over the body in last month	1.7	1.8	2.2	1.2	1.5
Exposure to tobacco smoke outside home	1.7	2.3	3.5	1.1	1.9
Eye problems/disorders: None of the above	1.7	1.9	3.6	-0.5	-1.9
Commuting to job workplace: Cycle	1.7	2.1	3.8	1.9	0.6
Hand grip strength (left)	1.6	4.3	4.3	-2.1	-2.1
Average weekly spirits intake	1.6	2.0	3.2	-1.8	-0.9
Ever highly irritable/argumentative for 2 days	1.6	1.9	3.4	-1.8	-0.6
Osteoporosis (self-reported)	1.6	1.9	3.3	-0.8	-1.8
Number of self-reported non-cancer illnesses	1.6	2.7	3.8	-1.9	-1.3
Coronary Artery Disease (CAD)	1.5	1.8	3.1	-1.8	-0.8
Diverticular disease/diverticulitis (self-reported)	1.5	1.8	2.4	-1.0	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.5	3.4	6.9	0.2	2.6
Mouth/teeth dental problems: Dentures	1.5	2.5	3.7	-1.2	-1.9
Alcohol intake frequency.	1.5	3.5	4.0	2.0	1.8
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	2.7	0.9	-1.7
Medication: Aspirin	1.5	1.9	2.8	1.7	1.0
Number of operations (self-reported)	1.5	2.3	3.4	-1.1	-1.8
Blood Platelet Count	1.4	16.7	32.7	-5.7	0.8
Maternal smoking around birth	1.4	2.0	2.5	-1.3	-1.6
Hair/balding pattern: Pattern 2	1.4	1.7	3.2	1.8	0.5
Neck or shoulder pain in last month	1.4	2.0	3.8	-0.3	2.0
Bipolar Disorder (2011)	1.3	1.3	2.5	-1.6	-0.3
Lupus	1.3	2.0	3.9	-0.3	-2.0
Hayfever, allergic rhinitis or eczema	1.3	2.8	3.5	-1.5	1.9
Falls in the last year	1.3	1.8	2.3	1.5	1.1
Gout (self-reported)	1.3	1.7	3.0	-0.7	1.7
Age at last live birth	1.3	1.8	2.5	-1.6	-1.1
Illnesses of father: High blood pressure	1.3	1.6	2.4	-0.9	1.5
Ovarian Cancer	1.2	1.6	2.4	1.6	0.9
Qualifications: A levels/AS levels or equivalent	1.2	2.6	4.6	2.2	0.8
Medication: Cholesterol lowering	1.2	1.9	2.0	-1.4	-1.3
High blood pressure (siblings)	1.2	1.8	2.3	-1.5	-1.1
Medication: Allopurinol	1.2	1.6	2.6	-1.6	0.8
Commuting to job workplace: Public transport	1.2	1.5	2.6	1.6	0.5
Bipolar Disorder or Schizophrenia	1.1	2.8	5.2	-2.3	-0.6
Mouth/teeth dental problems: Loose teeth	1.1	1.3	2.0	-1.4	-0.8
Knee pain experienced in last month	1.1	1.7	1.9	1.4	1.2
Medication for cholesterol	1.1	1.7	3.3	-1.8	-0.2
Medication: Blood pressure	1.1	2.1	3.4	1.8	-0.9
Crohns Disease (2017)	1.0	2.3	4.6	0.1	2.1
Crohns Disease (2012)	1.0	1.6	3.3	0.1	1.8
Chronotype (morning person)	1.0	2.2	3.5	-1.9	-1.0
Alcohol usually taken with meals	1.0	1.6	2.8	0.7	-1.7
Length of working week for main job	1.0	1.1	2.2	0.3	1.5
Birth weight	1.0	2.2	2.8	-1.3	-1.7
Leg fat percentage (right)	1.0	3.5	4.0	-1.7	-2.0
Medication: Omeprazole	1.0	1.2	1.6	-1.0	-1.3
Asthma (self-reported)	1.0	2.1	3.8	-1.9	-0.6
Miserableness	1.0	1.7	3.4	-0.0	1.8
Pack years of smoking	1.0	1.4	1.9	-1.4	-1.0
Schizophrenia (2018)	0.9	1.9	3.8	-1.9	0.1
Age at First Birth	0.9	1.3	2.1	1.4	0.7
Angina	0.9	1.1	2.3	-0.1	-1.5
Supplements: Zinc	0.9	1.0	1.9	0.4	1.4
Medication: Atenolol	0.9	1.2	2.3	0.2	-1.5
Diabetes (self-reported)	0.9	1.5	2.7	1.6	0.5
Asthma	0.9	1.7	3.1	-1.8	-0.6
Shortness of breath walking on level ground	0.9	1.1	2.0	1.4	0.5
Emphysema/chronic bronchitis	0.9	1.0	1.9	-1.4	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	1.0	-1.0	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	2.8	-0.9	-1.7
Average weekly champagne plus white wine intake	0.9	1.2	1.5	-1.0	-1.2
Bipolar Disorder (2018)	0.8	1.2	1.4	-1.2	-1.0
Irritable Bowel Disease (IBD)	0.8	1.8	3.6	-0.2	1.9
Medication: Co-codamol	0.8	1.0	1.6	-0.6	-1.3
Hand grip strength (right)	0.8	2.1	2.7	-1.2	-1.7
Allergy	0.8	1.9	3.4	1.9	-0.7
Alcohol intake versus 10 years previously	0.8	1.2	2.0	1.4	0.6
Hair/balding pattern: Pattern 3	0.8	1.2	1.8	-1.4	-0.8
Medication: Paracetamol	0.8	1.4	1.7	1.0	1.3
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.9	1.4	-0.3
Back pain experienced in last month	0.8	1.2	1.8	1.3	0.8
Ever taken oral contraceptive pill	0.8	0.9	1.6	0.4	1.3
Ever smoked	0.8	1.5	1.8	1.1	1.3
Diastolic blood pressure, automated reading	0.8	2.4	2.5	-1.5	1.6
Major Depression (MDD)	0.7	0.8	1.6	-1.2	-0.1
Average weekly fortified wine intake	0.7	0.8	1.4	1.2	0.5
Hearing difficulty/problems with background noise	0.7	1.0	1.9	-1.4	0.5
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	1.6	-1.3	0.4
Neuroticism score	0.7	1.4	2.1	-0.8	1.5
Noisy workplace	0.7	0.9	1.0	1.0	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.5	-0.6	1.2
Illnesses of mother	0.7	0.9	0.9	-0.9	-0.9
Breastfed as a baby	0.7	0.8	1.6	0.2	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	1.9	-1.4	0.3
Headache pain in last month	0.7	1.1	1.6	-1.3	0.8
Medication for cholesterol, blood pressure or diabetes	0.7	1.2	1.6	1.3	0.9
Loneliness, isolation	0.7	1.0	1.1	-1.0	1.0
Diabetes diagnosed by doctor	0.7	1.1	1.9	1.4	0.6
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	1.4	0.9	1.2
Illnesses of father: None of the above (group 1)	0.7	0.9	1.7	-0.1	-1.3
Mother’s age at death	0.7	0.9	1.7	0.2	1.3
Medication: Bendroflumethiazide	0.7	1.0	2.1	1.4	-0.0
Leg fat percentage (left)	0.7	2.4	3.1	-1.8	-1.3
Age started oral contraceptive pill	0.7	0.8	1.4	1.2	0.5
Ever depressed for a whole week	0.7	0.8	1.4	-1.2	-0.4
Alcohol drinker status: Previous	0.7	0.8	1.6	0.0	1.3
Smoking Status	0.6	1.3	2.2	0.7	1.5
Frequency of depressed mood in last 2 weeks	0.6	0.8	1.6	-1.3	0.1
Systolic blood pressure, automated reading	0.6	1.7	2.5	-0.9	-1.6
Pack years adult smoking proportion	0.6	0.9	1.1	-1.0	-0.8
Serious illness, injury or assault to yourself	0.6	0.7	1.4	1.2	-0.2
Number of incorrect matches in round	0.6	0.9	1.6	0.6	1.3
Worry too long after embarrassment	0.6	1.0	1.8	1.3	0.5
Angina (self-reported)	0.6	0.7	1.4	0.3	-1.2
Mood swings	0.6	1.1	1.9	0.6	1.4
Ever had bowel cancer screening	0.6	0.7	1.3	1.1	-0.2
Mineral and other dietary supplements	0.6	0.7	1.1	0.6	1.1
Medication: Gliclazide	0.6	0.7	1.4	1.2	0.0
Medication: Lisinopril	0.6	0.8	1.3	-0.5	-1.2
Alzheimer’s Disease (in father)	0.5	0.6	0.6	0.7	0.8
Ulcerative Colitis (UC)	0.5	0.9	1.8	-0.1	1.4
Neuroticism (2016)	0.5	0.7	0.9	-0.9	0.7
Triglycerides	0.5	0.8	1.6	0.2	1.3
Cardiovascular Disease	0.5	1.7	1.8	-1.3	-1.3
Type 2 Diabetes (T2D) (2018)	0.5	0.9	1.7	0.4	1.3
Relative age voice broke	0.5	0.8	1.3	1.1	0.6
Taking other prescription medications	0.5	0.8	1.0	-1.0	-0.8
Worrier / anxious feelings	0.5	0.9	1.6	-0.4	1.3
Number of live births	0.5	0.7	1.3	-0.4	-1.1
Birth weight of first child	0.5	0.9	1.6	-0.4	1.3
Number of children fathered	0.5	0.5	1.0	-0.2	-1.0
Heart disease (mother)	0.5	0.6	1.3	0.1	-1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.1	-1.1	0.0
Number of full sisters	0.5	0.6	1.2	-1.1	-0.2
Had major operations	0.5	0.6	0.6	-0.8	-0.8
Hypertension (Self-reported)	0.5	1.3	2.6	-0.1	-1.6
Commuting to job workplace: Walk	0.5	0.6	1.1	-1.0	0.3
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.1	-0.3	-1.1
High cholesterol (Self-reported)	0.5	0.9	1.8	-1.3	-0.3
Alcohol drinker status: Never	0.5	0.6	0.6	0.8	-0.8
Irritability	0.5	0.8	1.4	-0.5	1.2
Supplements: Calcium	0.5	0.5	0.7	0.9	0.5
Alzheimer’s Disease (including proxy)	0.4	0.6	1.1	-0.1	1.1
Breast Cancer	0.4	0.9	1.8	1.3	-0.1
Mean Putamen Volume	0.4	0.5	0.9	0.9	0.2
Blood White Count	0.4	3.2	6.4	-2.5	0.0
Fed-up feelings	0.4	0.7	1.2	-0.5	1.1
High blood pressure (mother)	0.4	0.6	1.1	0.2	1.0
Medication: Ramipril	0.4	0.5	0.9	0.9	0.2
Illnesses of siblings	0.4	0.6	0.8	0.9	0.6
Happiness	0.4	0.5	0.9	1.0	-0.0
Pulse wave Arterial Stiffness index	0.4	0.4	0.7	0.8	-0.4
Standing height	0.4	3.6	6.3	2.5	1.0
Tense / ‘highly strung’	0.4	0.7	1.0	-1.0	0.6
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.9	-1.0	0.1
Body fat percentage	0.4	1.5	1.8	-1.1	-1.4
Medication: Ibuprofen	0.4	0.4	0.7	-0.8	0.4
Family relationship satisfaction	0.4	0.5	1.0	0.2	1.0
Illnesses of father: Heart disease	0.4	0.5	0.6	-0.7	-0.8
Long-standing illness, disability or infirmity	0.4	0.6	1.1	1.0	0.2
Unable to work because of sickness or disability	0.4	0.5	0.6	0.7	0.8
Vascular/heart problems diagnosed by doctor	0.4	1.1	2.2	0.1	1.5
Depression (Nagel 2018)	0.3	0.5	0.9	-0.9	-0.2
Alzheimer’s Disease (in mother)	0.3	0.4	0.6	-0.8	0.3
Blood Red Count	0.3	3.2	3.7	-1.9	-1.7
Heel T-Score	0.3	2.5	4.9	0.4	2.2
Waist Hip Ratio (WHR)	0.3	1.1	2.0	0.5	1.4
Systolic Blood Pressure	0.3	1.4	2.8	-0.3	-1.7
Hypothyroidism (self reported)	0.3	0.8	1.1	-1.0	0.7
Hair Pigment	0.3	8.7	13.2	3.6	-2.0
Hearing difficulty/problems: Yes	0.3	0.5	1.0	-0.0	1.0
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.6	-0.3	0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	0.5	-0.7	-0.5
Townsend deprivation index at recruitment	0.3	0.4	0.5	0.7	-0.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.5	0.4	0.7
Sitting height	0.3	2.5	3.7	1.9	1.1
Financial difficulties in last 2 years	0.3	0.4	0.6	0.5	-0.8
Mouth/teeth dental problems	0.3	0.4	0.7	0.3	0.8
Medication: Simvastatin	0.3	0.4	0.6	-0.5	-0.8
Arm fat percentage (right)	0.3	1.1	1.6	-0.8	-1.3
Peak expiratory flow (PEF)	0.3	0.8	1.5	1.2	0.3
Health satisfaction	0.3	0.4	0.4	0.6	0.6
Leg fat mass (right)	0.3	1.2	1.4	-1.0	-1.2
Chest pain or discomfort	0.3	0.4	0.4	0.7	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.6	-0.4	0.7
Arm fat percentage (left)	0.3	1.1	1.6	-0.8	-1.2
Qualifications: nursing, teaching	0.3	0.4	0.9	0.9	-0.1
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.7	0.1	0.8
Pain type(s) experienced in last month: Hip pain	0.3	0.3	0.6	0.2	-0.8
Cholesterol lowering medication	0.3	0.4	0.6	0.7	-0.5
Heart attack/myocardial infarction (self-reported)	0.3	0.3	0.6	0.2	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.1	1.1	0.3
Lung FVC	0.2	0.9	1.7	-1.3	-0.2
Tanning	0.2	2.4	3.9	0.9	2.0
Sensitivity / hurt feelings	0.2	0.3	0.4	-0.5	-0.6
Vitamin and mineral supplements	0.2	0.3	0.4	0.7	-0.4
Medication: Metformin	0.2	0.4	0.4	0.6	0.6
Trunk fat percentage	0.2	0.8	1.1	-0.7	-1.1
Qualifications: CSEs or equivalent	0.2	0.2	0.5	-0.1	0.7
High blood pressure	0.2	0.7	1.4	-0.1	-1.2
Body mass index (BMI)	0.2	1.0	1.3	-1.1	-0.9
Nervous feelings	0.2	0.4	0.8	-0.9	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.5	-0.2	0.7
Heart attack	0.2	0.3	0.5	0.2	0.7
Impedance of arm (right)	0.2	0.9	1.7	1.3	0.2
Hip circumference	0.2	1.0	1.7	-0.4	-1.3
Prospective memory result	0.2	0.2	0.4	-0.7	0.0
Impedance of arm (left)	0.2	0.7	1.4	1.2	0.1
Arm fat mass (right)	0.2	0.8	1.2	-0.6	-1.1
Exposure to tobacco smoke at home	0.2	0.2	0.3	-0.5	0.4
Pulse wave reflection index	0.2	0.2	0.4	0.6	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.4	-0.6	0.6
Number of full brothers	0.2	0.2	0.4	0.6	-0.2
Wheeze or whistling in the chest in last year	0.2	0.3	0.5	-0.7	0.4
Age at first live birth	0.2	0.4	0.6	-0.4	-0.8
Pulse wave peak to peak time	0.2	0.3	0.4	-0.6	0.4
Qualifications: College or University degree	0.2	0.6	0.7	0.8	-0.8
Medication for pain relief, constipation, heartburn	0.2	0.4	0.7	-0.3	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.6	0.8	0.1
Leg fat-free mass (right)	0.2	0.9	1.1	0.8	1.0
Leg predicted mass (right)	0.2	0.9	1.1	0.8	1.0
Guilty feelings	0.2	0.2	0.4	0.6	0.3
Hearing aid user	0.2	0.2	0.3	0.5	0.3
Eye problems/disorders: Glaucoma	0.2	0.3	0.5	0.7	0.1
Myopia	0.2	0.4	0.5	0.7	0.5
Leg fat mass (left)	0.2	0.9	1.2	-1.1	-0.8
Depressed Affect (Nagel 2018)	0.1	0.3	0.6	0.1	0.7
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.3	0.6	0.1
Neuroticism (Nagel 2018)	0.1	0.3	0.5	0.7	0.3
Worry (Nagel 2018)	0.1	0.2	0.4	-0.6	-0.2
Fasting Glucose	0.1	0.1	0.2	-0.4	-0.2
HbA1C	0.1	0.1	0.1	0.4	0.2
HDL Cholesterol	0.1	0.2	0.4	-0.1	-0.6
Rheumatoid Arthritis	0.1	0.1	0.3	-0.1	0.5
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.1	0.3	0.4
Ulcerative Colitis	0.1	0.2	0.3	-0.4	0.5
BMI	0.1	0.4	0.6	-0.5	-0.8
Height	0.1	1.9	3.6	1.9	0.4
Neuroticism	0.1	0.3	0.5	-0.7	0.2
Relative age of first facial hair	0.1	0.2	0.4	0.7	-0.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.3	-0.3	0.5
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	0.3	0.3
Diabetes (father)	0.1	0.1	0.1	-0.4	0.2
Diabetes (mother)	0.1	0.1	0.2	0.3	0.4
Impedance of leg (right)	0.1	0.5	1.0	0.2	-1.0
Leg fat-free mass (left)	0.1	0.6	0.8	0.9	0.6
Current tobacco smoking	0.1	0.2	0.3	-0.2	0.6
Age when periods started (menarche)	0.1	0.3	0.3	0.6	0.5
Supplements: Glucosamine	0.1	0.2	0.2	0.5	-0.3
Medication: Levothyroxine sodium	0.1	0.2	0.5	-0.2	0.7
Leg predicted mass (left)	0.1	0.5	0.7	0.8	0.5
Trunk fat mass	0.1	0.5	0.8	-0.5	-0.9
Past tobacco smoking	0.1	0.1	0.1	-0.4	-0.3
Had other major operations	0.1	0.2	0.3	0.5	-0.2
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.3	-0.5	0.1
Trunk fat-free mass	0.1	0.7	1.2	1.1	0.4
Time employed in main current job	0.1	0.1	0.3	0.1	-0.5
Father’s age at death	0.1	0.1	0.3	0.5	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.3	0.5	0.5
Pulse rate	0.1	0.2	0.3	0.2	0.5
Trunk predicted mass	0.1	0.6	1.1	1.1	0.3
Loud music exposure frequency	0.1	0.1	0.2	-0.5	0.2
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	0.3	-0.3
Glaucoma (self-reported)	0.1	0.1	0.2	0.4	-0.3
Forced vital capacity (FVC), Best measure	0.1	0.2	0.4	-0.7	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	0.0	0.4
Medication: Seretide 50 evohaler	0.1	0.1	0.1	-0.2	-0.4
Whole body fat mass	0.1	0.6	0.7	-0.6	-0.9
Pulse rate, automated reading	0.1	0.5	0.8	-0.9	0.4
Comparative height size at age 10	0.1	0.4	0.6	0.7	0.4
Suffer from ‘nerves’	0.1	0.2	0.3	-0.3	-0.5
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.3	-0.5	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.1	0.3	0.1
Illnesses of siblings: Diabetes	0.1	0.1	0.2	-0.3	-0.4
Whole body fat-free mass	0.1	0.7	1.0	1.0	0.6
Whole body water mass	0.1	0.6	0.9	1.0	0.6
Arm fat mass (left)	0.1	0.6	0.9	-0.6	-1.0
Medication: Atorvastatin	0.1	0.2	0.3	0.2	-0.6
Basal metabolic rate	0.1	0.5	0.8	0.9	0.5
Arm fat-free mass (left)	0.1	0.4	0.5	0.7	0.6
Risk taking	0.1	0.2	0.2	0.3	0.5
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	0.3	0.3
Heart disease (siblings)	0.1	0.1	0.2	0.5	0.1
Arm predicted mass (left)	0.1	0.3	0.4	0.6	0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.2
LDL Cholesterol	0.0	0.0	0.1	0.1	0.2
Blood Eosinophil Count	0.0	0.1	0.1	0.2	-0.3
Severe depression (siblings)	0.0	0.0	0.0	-0.2	-0.2
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.0	0.1	0.1
Stomach or abdominal pain in last month	0.0	0.1	0.1	0.0	-0.3
Impedance of leg (left)	0.0	0.0	0.0	-0.0	-0.2
Waist circumference	0.0	0.1	0.1	0.1	0.3
Had menopause	0.0	0.0	0.1	-0.3	-0.1
Forced vital capacity (FVC)	0.0	0.0	0.0	-0.2	0.0
Weight	0.0	0.1	0.1	0.2	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.1	0.3	0.0
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.1	-0.3	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.2	-0.2	0.5
Blood clot in the leg (DVT)	0.0	0.1	0.1	0.2	-0.3
Medication: Amlodipine	0.0	0.0	0.0	0.0	0.1
Chronic bronchitis/emphysema (mother)	0.0	0.0	0.0	0.0	0.1
Arm fat-free mass (right)	0.0	0.1	0.1	0.3	0.3
Medication: Blood pressure	0.0	0.1	0.1	-0.3	-0.3
Arm predicted mass (right)	0.0	0.2	0.2	0.4	0.5
Overall health rating	0.0	0.1	0.1	0.1	0.3
Smoking status: Previous	0.0	0.0	0.0	0.1	0.1
Average weekly red wine intake	0.0	0.0	0.0	-0.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.1	0.3	-0.1
Osteoarthritis (self-reported)	0.0	0.0	0.0	-0.1	0.1
Smoking status: Current	0.0	0.1	0.1	-0.1	0.3
Financial situation satisfaction	0.0	0.0	0.0	-0.0	-0.2
Medication: Paracetamol	0.0	0.1	0.1	0.4	0.1
Ever had prostate specific antigen (PSA) test	0.0	0.1	0.1	0.1	0.3
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.0	0.2	0.0
Impedance of whole body	0.0	0.2	0.4	0.6	0.0

Hub : Genes

TAC4

Models

Trait associations