TWAS hub - TBC1D4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0660	0.0280	1.1e-02	0.065	0.001	0.047	0.046	0.060	2.4e-08	2.6e-01	2.2e-06	2.5e-06	9.0e-08
2	GTEx	Adipose Subcutaneous	0.2620	0.0650	8.4e-07	0.088	NA	0.065	NA	0.059	1.1e-07	NA	4.8e-06	NA	1.4e-05
3	GTEx	Artery Aorta	0.2850	0.0650	4.7e-06	0.109	NA	0.107	NA	0.092	1.4e-06	NA	1.7e-06	NA	9.2e-06
4	GTEx	Artery Tibial	0.2035	0.0631	3.9e-04	0.014	NA	0.041	NA	0.035	2.4e-02	NA	3.6e-04	NA	9.5e-04
5	GTEx	Brain Cerebellum	0.2350	0.0830	3.1e-03	0.025	NA	0.122	NA	0.075	6.3e-02	NA	1.9e-04	NA	3.2e-03
6	GTEx	Brain Cortex	0.3920	0.1000	3.4e-04	0.121	NA	0.058	NA	0.085	3.3e-04	NA	1.1e-02	NA	2.4e-03
7	GTEx	Breast Mammary Tissue (Male)	0.0355	0.0600	3.2e-01	-0.013	NA	0.015	NA	-0.009	9.9e-01	NA	1.4e-01	NA	5.7e-01
8	GTEx	Breast Mammary Tissue (Female)	0.1451	0.0866	7.8e-02	-0.007	NA	-0.009	NA	0.011	6.1e-01	NA	7.7e-01	NA	1.5e-01
9	GTEx	Cells EBV-transformed lymphocytes	0.4730	0.0900	2.3e-05	0.293	NA	0.266	NA	0.349	3.6e-10	NA	3.1e-09	NA	3.5e-12
10	GTEx	Colon Transverse	0.2530	0.0730	1.5e-03	0.119	NA	0.123	NA	0.153	2.9e-06	NA	1.9e-06	NA	9.3e-08
11	GTEx	Esophagus Mucosa	0.2690	0.0570	1.5e-06	0.210	NA	0.221	NA	0.211	4.6e-14	NA	8.3e-15	NA	3.7e-14
12	GTEx	Lung	0.1416	0.0449	2.1e-04	0.086	NA	0.043	NA	0.057	4.3e-07	NA	3.1e-04	NA	3.5e-05
13	GTEx	Nerve Tibial	0.3880	0.0588	2.2e-13	0.256	NA	0.307	NA	0.303	3.6e-18	NA	3.6e-22	NA	7.5e-22
14	GTEx	Skin Not Sun Exposed Suprapubic	0.2120	0.0550	2.7e-05	0.236	NA	0.232	NA	0.231	3.7e-13	NA	5.9e-13	NA	7.0e-13
15	GTEx	Skin Sun Exposed Lower leg	0.3740	0.0590	4.1e-13	0.213	NA	0.232	NA	0.226	1.6e-17	NA	4.4e-19	NA	1.4e-18
16	GTEx	Thyroid	0.2270	0.0480	9.8e-08	0.212	NA	0.220	NA	0.209	3.8e-16	NA	8.8e-17	NA	6.4e-16
17	METSIM	Adipose	0.1216	0.0269	5.8e-12	0.113	0.081	0.098	0.106	0.110	1.5e-16	3.9e-12	1.7e-14	1.3e-15	3.9e-16
18	NTR	Blood	0.0784	0.0175	2.1e-11	0.035	0.049	0.060	0.055	0.056	1.6e-11	1.5e-15	1.1e-18	3.0e-17	2.1e-17
19	YFS	Blood	0.2230	0.0302	0.0e+00	0.130	0.172	0.201	0.200	0.205	3.5e-40	6.6e-54	8.5e-64	2.7e-63	4.4e-65
20	TCGA	Breast Invasive Carcinoma	0.0557	0.0193	3.6e-05	0.044	0.033	0.035	NA	0.041	2.4e-09	2.0e-07	7.5e-08	NA	7.9e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	8	9	10	11	12	13	14	15	16	17	18	19	20
Commuting to job workplace: Walk	4.8	5.1	12.3	0.7	2.2	2.8	1.6	1.8	2.8	-0.3	2.7	1.0	2.4	2.4	2.7	2.3	2.3	2.5	2.3	3.5	3.4	1.9
Medication: Metformin	4.5	6.4	12.0	-1.0	-3.1	-3.1	-2.6	-1.0	-3.1	-0.8	-0.7	-2.9	-3.1	-3.2	-3.1	-3.1	-3.5	-3.1	-3.2	-2.1	-2.2	0.2
Happiness	3.9	4.7	9.2	1.5	2.8	1.7	1.7	0.8	2.8	0.5	0.2	1.8	2.8	2.9	2.9	2.8	3.0	2.8	2.8	2.2	2.2	-0.7
Medication: Bendroflumethiazide	3.6	5.5	11.4	-2.0	-2.3	-3.4	-3.3	-0.6	-1.7	0.1	-1.4	-2.9	-2.7	-2.5	-2.6	-2.7	-2.9	-2.8	-2.4	-2.9	-2.7	-0.7
Neck or shoulder pain in last month	3.1	4.4	9.1	0.8	-2.0	-1.5	-1.2	-1.2	-3.0	0.9	0.1	-2.4	-2.7	-2.9	-3.0	-2.8	-3.0	-2.4	-3.0	-1.7	-1.7	0.6
Prostate Cancer	3.0	4.2	8.4	1.0	-2.7	-1.8	-0.9	0.1	-2.5	-1.8	-1.5	-1.1	-2.5	-2.7	-2.5	-2.5	-2.3	-2.5	-2.2	-2.5	-2.9	-1.4
Friendships satisfaction	3.0	3.7	10.0	0.6	2.1	1.9	1.1	1.5	1.7	1.0	2.0	1.4	2.3	2.4	2.0	2.3	3.2	2.2	2.2	2.1	2.7	0.6
Serious illness, injury or assault of a close relative in last 2 years	2.8	3.2	8.7	0.6	2.9	0.2	1.3	-0.5	2.2	2.1	-0.3	1.2	2.3	2.5	2.5	2.4	2.5	2.1	2.2	1.3	1.1	-0.9
Chronic bronchitis/emphysema (father)	2.7	3.2	7.0	0.5	2.3	1.6	0.3	1.5	1.9	0.1	-0.0	0.6	2.6	2.4	2.6	2.4	1.8	2.6	2.5	2.0	1.9	-0.6
Diabetes (self-reported)	2.7	4.2	8.7	-1.6	-2.2	-2.9	-2.4	-1.4	-2.6	-1.1	-0.2	-2.6	-2.4	-2.5	-2.4	-2.4	-2.8	-2.3	-2.3	-1.2	-1.4	-0.0
Financial difficulties in last 2 years	2.5	3.4	10.6	1.6	1.1	3.2	2.2	1.7	2.2	-0.2	0.9	0.9	2.1	2.4	2.1	2.2	2.1	1.9	2.3	1.6	2.1	0.5
Health satisfaction	2.3	2.9	6.5	0.8	2.6	1.9	1.3	0.2	1.6	-0.2	0.8	1.4	2.1	2.4	2.1	2.2	2.1	2.0	2.0	2.3	2.0	-0.0
Mother’s age at death	2.3	2.9	7.2	-1.8	-2.1	-1.1	-1.1	-1.1	-1.5	0.4	0.3	-1.0	-2.6	-2.0	-2.2	-2.3	-1.8	-2.7	-2.5	-1.9	-1.3	0.4
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.6	6.2	0.4	1.3	1.1	0.3	2.0	2.5	-0.5	0.5	1.5	1.9	1.6	2.4	1.9	2.1	2.1	2.0	2.2	1.9	0.1
Family relationship satisfaction	2.1	2.5	4.9	0.1	1.3	2.1	0.9	1.0	1.7	-1.0	1.3	1.2	2.0	1.9	1.6	2.0	2.2	2.0	2.0	1.8	2.2	-0.1
Financial situation satisfaction	2.1	2.7	6.2	1.0	1.3	2.2	1.9	1.1	1.8	-1.9	-0.7	1.6	2.1	2.2	1.6	2.0	2.5	1.9	1.9	0.9	1.0	-0.4
Alzheimer’s Disease (in mother)	2.0	2.4	5.0	0.3	1.8	2.2	2.2	0.6	1.0	0.3	1.5	1.8	1.6	1.9	1.7	1.6	2.1	1.7	1.5	1.5	1.9	0.7
Lupus	2.0	3.1	9.1	-0.5	-2.5	-1.5	-0.7	-2.4	-2.3	-3.0	-1.4	-1.3	-1.4	-1.7	-2.3	-1.7	-1.9	-1.3	-1.8	-2.0	-1.8	-0.6
Number of treatments/medications taken	2.0	3.5	8.1	-1.4	-2.3	-2.0	-1.9	-1.5	-2.8	-1.3	-0.9	-1.0	-2.1	-2.1	-2.6	-2.2	-2.4	-2.0	-2.1	-1.8	-1.9	-0.3
Taking other prescription medications	2.0	3.1	8.1	-1.1	-1.6	-2.2	-2.8	-0.6	-2.8	-0.3	1.0	-2.3	-1.8	-1.8	-2.1	-1.9	-2.4	-1.8	-2.1	-1.1	-0.6	1.0
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	4.8	-0.5	-1.5	-1.6	-1.1	-0.5	-1.8	0.3	-1.4	-1.5	-1.8	-2.0	-2.0	-1.9	-1.9	-1.8	-1.9	-2.0	-2.2	-0.8
Medication: Allopurinol	2.0	2.7	5.6	0.4	2.2	1.1	0.3	1.3	1.9	0.1	1.3	1.7	2.0	2.2	2.4	2.1	1.7	2.1	2.2	1.6	2.1	-0.1
Blood Red Count	1.9	18.1	225.0	-15.0	-2.9	-3.3	-7.8	-3.2	-1.2	0.3	0.0	-1.9	-2.3	-2.2	-2.2	-2.2	-2.5	-2.2	-2.6	-1.1	-0.3	1.0
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.4	11.9	-1.7	-1.4	-1.8	-3.4	0.9	-1.4	-2.5	0.6	-2.7	-1.2	-1.7	-1.2	-1.5	-1.3	-1.0	-1.3	0.0	0.2	0.4
Commuting to job workplace: Public transport	1.9	2.3	4.7	-1.4	-1.1	-2.1	-2.2	0.4	-1.8	-0.3	1.3	-2.1	-1.9	-1.6	-1.8	-1.9	-1.9	-2.0	-1.9	-0.5	-0.1	0.7
Medication: Levothyroxine sodium	1.8	3.1	7.5	0.6	1.5	1.4	0.2	2.3	2.4	1.6	2.1	0.8	1.6	1.4	2.0	1.4	1.9	1.5	1.5	2.7	2.5	2.6
Bipolar Disorder (2018)	1.7	2.6	5.8	-0.1	1.1	1.8	1.1	0.6	1.8	1.1	0.3	1.1	1.9	2.3	2.4	2.0	2.2	1.8	2.3	2.2	1.9	0.0
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	4.5	-0.1	-1.8	-1.2	-1.5	-1.3	-1.8	-0.4	-0.7	-2.1	-1.4	-1.6	-1.4	-1.5	-1.8	-1.3	-1.7	-1.4	-1.1	-0.6
High blood pressure	1.7	4.7	9.8	-1.1	-2.2	-2.8	-2.0	-0.7	-2.3	0.9	0.0	-2.9	-2.7	-2.7	-2.5	-2.7	-3.1	-2.6	-2.6	-2.5	-2.0	0.0
Headache pain in last month	1.7	2.9	13.1	-2.8	-0.8	-2.0	-3.6	-0.9	-1.8	-1.1	-0.5	-2.6	-1.5	-1.7	-1.2	-1.5	-1.8	-1.4	-2.0	-0.4	-0.3	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	5.5	-1.8	-1.3	-1.9	-2.3	-0.6	-1.9	-0.3	-0.4	-2.2	-1.4	-1.7	-1.6	-1.6	-2.3	-1.5	-1.5	-1.2	-0.9	-0.6
Vascular/heart problems diagnosed by doctor	1.7	4.8	10.5	0.6	2.2	2.7	1.6	0.6	2.3	-0.9	0.1	2.7	2.8	2.8	2.6	2.8	3.2	2.7	2.6	2.5	2.2	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	7.3	-0.0	1.2	1.2	0.7	0.5	1.5	-1.1	-0.8	2.7	1.8	2.1	1.4	1.8	1.3	1.9	1.8	0.8	0.2	-0.9
Hypertension (Self-reported)	1.6	4.3	9.1	-0.8	-2.1	-2.7	-1.7	-0.5	-2.2	0.9	0.3	-2.7	-2.6	-2.6	-2.3	-2.6	-3.0	-2.6	-2.5	-2.3	-1.8	0.2
Commuting to job workplace: Cycle	1.6	1.9	9.7	-1.7	-0.9	-1.9	-2.5	-0.3	-1.0	-1.1	-0.4	-3.1	-1.2	-1.6	-0.9	-1.3	-1.4	-1.0	-1.3	-0.8	-0.6	0.2
High blood pressure (siblings)	1.5	2.2	6.2	-1.2	-1.6	-1.5	-2.0	-0.7	-2.5	-0.1	0.6	-1.2	-2.0	-1.7	-1.6	-1.8	-2.0	-1.7	-1.9	-0.7	-0.7	0.7
Medication: Ibuprofen	1.5	1.8	8.3	-0.8	-1.3	-2.0	-2.9	0.9	-1.2	-1.5	0.3	-2.4	-1.1	-1.7	-1.1	-1.4	-1.3	-1.0	-1.2	-0.3	-0.2	0.2
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	4.5	-1.3	-2.1	-1.5	-1.5	0.4	-1.4	-1.3	0.3	-0.7	-1.7	-1.7	-1.7	-1.8	-1.5	-1.6	-1.6	-1.1	-0.9	0.7
HbA1C	1.4	1.6	11.4	1.9	-0.1	-0.1	0.2	0.0	-1.2	0.5	3.4	-1.8	-0.6	-0.6	-0.6	-0.5	-0.9	-0.4	-0.7	0.6	1.4	2.7
Type 2 Diabetes (T2D) (2012)	1.4	1.7	3.7	1.3	-1.5	-1.5	-0.7	-1.9	-1.5	-0.5	-1.7	-1.3	-1.4	-1.3	-1.3	-1.3	-1.2	-1.5	-1.4	-0.9	-1.6	0.0
Ever had hysterectomy (womb removed)	1.4	1.6	4.5	0.5	-2.1	-1.7	-1.2	0.6	-1.1	-1.4	-0.5	-1.1	-1.6	-1.6	-1.4	-1.5	-1.5	-1.6	-1.4	-0.3	-1.1	-0.0
Peak expiratory flow (PEF)	1.4	3.1	6.7	0.4	2.2	1.9	2.0	0.9	2.1	-0.7	-0.1	1.2	2.1	2.5	2.6	2.3	2.4	1.8	2.3	1.9	1.8	-0.2
Medication: Blood pressure	1.4	2.7	5.7	-0.7	-2.3	-1.8	-1.6	-0.7	-0.9	1.2	-1.7	-1.1	-2.0	-1.7	-1.8	-1.9	-1.9	-2.0	-1.8	-2.2	-2.4	-0.9
Fractured/broken bones in last 5 years	1.4	1.7	3.9	1.8	0.5	1.3	2.0	-1.0	1.3	1.3	-0.2	1.6	1.5	1.6	1.0	1.6	1.4	1.6	1.4	1.5	1.0	0.4
Serious illness, injury or assault to yourself	1.3	1.6	8.0	-0.5	1.5	1.2	0.8	-0.5	1.1	2.8	1.4	-0.1	1.1	1.1	0.9	1.2	1.6	1.0	1.0	1.5	1.6	1.2
Loud music exposure frequency	1.3	1.5	4.7	-2.2	1.5	1.1	-0.9	1.5	1.5	0.9	0.3	0.6	1.1	1.1	1.4	1.3	1.0	1.0	1.3	1.6	1.4	0.6
Age started oral contraceptive pill	1.3	1.7	5.0	-2.2	-2.0	-1.0	-1.2	-1.8	-1.1	-2.0	-1.1	0.2	-0.9	-0.9	-1.5	-1.0	-0.8	-0.7	-1.0	-1.5	-1.5	-0.8
Ever depressed for a whole week	1.3	1.5	4.1	-0.5	-1.1	-2.0	-1.2	-0.3	-1.0	-0.5	-1.5	-1.4	-1.3	-1.3	-1.4	-1.3	-1.1	-1.3	-1.4	-1.3	-1.7	-1.3
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	5.7	-0.4	1.5	0.9	-0.0	1.1	1.1	0.7	0.8	0.3	1.6	1.6	1.6	1.6	1.0	1.7	1.5	2.4	1.9	0.8
Current tobacco smoking	1.2	2.0	7.4	1.4	1.8	2.0	1.5	2.7	1.1	0.6	0.9	1.1	1.5	1.2	1.2	1.5	1.5	1.5	1.6	1.5	1.2	0.5
Leg pain on walking	1.2	1.5	4.9	1.5	1.4	1.1	0.7	2.2	0.6	-0.4	1.1	-0.2	1.2	1.2	1.3	1.1	1.0	1.3	1.3	1.7	1.7	0.5
Supplements: Vitamin C	1.2	1.4	2.9	-1.6	-1.7	-0.6	-1.5	-0.8	-1.4	-0.3	1.0	-1.6	-1.3	-1.3	-1.2	-1.2	-1.1	-1.4	-1.6	0.0	0.1	1.4
Ever had bowel cancer screening	1.2	1.4	3.8	-2.0	1.2	1.2	-0.2	-0.5	0.7	1.2	0.9	1.2	1.3	1.3	1.2	1.4	1.0	1.1	1.1	1.7	1.9	0.4
Alcohol drinker status: Never	1.2	1.4	3.3	1.0	-1.5	-0.5	-0.5	0.6	-1.1	-0.8	-0.9	-0.9	-1.5	-1.4	-1.8	-1.6	-1.0	-1.3	-1.4	-1.7	-1.8	0.5
Bipolar Disorder (2011)	1.1	1.1	2.4	-0.7	1.4	0.2	0.0	1.3	1.5	-0.3	0.5	0.7	1.2	1.4	1.5	1.2	1.1	1.1	1.4	1.3	1.2	0.0
Rheumatoid Arthritis	1.1	1.5	9.4	-2.2	1.2	-1.0	-1.5	-0.5	0.8	0.3	-3.1	0.2	1.2	1.1	1.1	1.2	0.9	1.4	1.1	0.1	-0.6	0.0
Ulcerative Colitis	1.1	1.6	4.1	-0.4	-0.9	-1.7	-1.4	-0.5	-2.0	0.5	-0.4	-2.0	-1.5	-1.6	-1.5	-1.5	-1.6	-1.4	-1.5	-1.1	-0.8	0.0
Cardiovascular Disease	1.1	3.5	10.2	-0.2	-2.4	-2.1	-1.1	-0.7	-1.7	0.2	-0.2	-3.2	-2.3	-2.2	-2.1	-2.4	-2.7	-2.3	-2.2	-2.1	-1.5	0.1
Noisy workplace	1.1	1.3	3.4	-0.1	1.7	0.6	0.4	-0.6	1.2	1.5	-0.2	1.2	1.3	1.4	1.8	1.4	1.3	1.4	1.3	0.8	0.8	-1.4
Medication: Blood pressure	1.1	2.0	5.0	-1.9	-1.0	-2.2	-1.8	-0.9	-1.9	-0.3	-0.3	-1.0	-1.5	-1.9	-1.6	-1.6	-1.9	-1.4	-1.5	-1.1	-1.5	-0.3
Medication for cholesterol	1.1	1.7	3.8	0.7	1.7	0.7	0.8	0.5	0.5	-0.3	1.8	1.2	1.6	1.5	1.3	1.6	1.4	1.7	1.5	1.9	1.9	0.9
Basal cell carcinoma (self-reported)	1.1	1.4	3.3	1.3	1.8	1.6	1.2	0.3	1.0	1.0	1.0	1.5	1.3	0.9	1.4	1.2	1.3	1.4	1.0	1.1	0.9	0.4
Alcohol drinker status: Previous	1.1	1.3	4.3	1.4	2.1	1.7	1.6	-0.4	0.9	-0.6	-0.2	0.7	1.2	1.1	1.5	1.2	1.1	1.2	1.1	1.2	0.8	-0.8
Bipolar Disorder or Schizophrenia	1.0	2.4	6.7	1.6	1.0	2.6	2.4	-0.2	1.0	0.5	1.5	0.9	1.5	1.8	1.8	1.6	1.8	1.4	1.7	2.0	1.9	0.0
Worry (Nagel 2018)	1.0	2.0	8.7	-1.9	-1.5	-2.0	-2.9	-1.2	-1.9	-1.7	0.9	-1.5	-1.0	-1.0	-1.4	-1.0	-1.8	-1.0	-1.1	-0.7	-0.1	0.0
Major Depression (MDD)	1.0	1.3	6.4	-2.5	-0.5	-1.2	-1.8	-1.4	-0.9	0.1	-1.4	-0.1	-0.9	-0.7	-0.8	-0.8	-0.6	-1.1	-0.9	-0.5	-1.2	-1.6
LDL Cholesterol	1.0	1.6	3.9	0.0	1.6	1.1	1.0	-0.5	1.7	0.4	0.8	0.8	1.4	1.6	2.0	1.5	1.5	1.5	1.5	1.6	1.6	0.0
Had other major operations	1.0	1.2	2.9	0.0	-1.2	-1.1	-0.4	-0.6	-1.3	0.1	-0.0	-0.9	-1.7	-1.5	-1.4	-1.6	-1.2	-1.7	-1.5	-0.8	-0.9	-0.5
Alcohol intake versus 10 years previously	1.0	1.4	3.4	-1.1	-1.3	-1.9	-1.6	-0.6	-1.3	0.7	-0.8	-1.4	-1.2	-1.3	-1.0	-1.2	-1.6	-1.1	-1.4	-0.9	-1.3	-1.0
Pulse wave Arterial Stiffness index	1.0	1.1	4.1	0.1	-0.4	-1.8	-1.0	0.8	-1.0	2.0	0.1	-1.9	-1.0	-1.0	-1.0	-0.9	-0.9	-1.0	-0.8	-1.2	-0.5	0.7
Gout (self-reported)	1.0	1.4	3.9	0.7	0.9	0.9	0.6	0.6	1.3	-0.2	0.9	2.0	1.4	1.7	1.5	1.5	1.4	1.5	1.5	1.1	1.3	-0.5
Emphysema/chronic bronchitis	1.0	1.1	3.9	-1.0	2.0	0.3	-0.4	1.0	1.1	1.9	-0.4	0.1	1.1	1.2	1.3	1.0	1.0	1.4	0.9	0.8	0.6	-0.8
Medication: Omeprazole	1.0	1.2	3.3	-0.3	1.4	1.1	0.1	1.0	0.7	1.0	0.1	0.1	1.5	1.4	1.5	1.4	0.8	1.5	1.4	1.8	1.2	0.3
Ever taken oral contraceptive pill	1.0	1.1	6.4	-2.5	0.8	0.5	-0.8	0.6	1.0	-1.6	0.3	0.1	1.0	1.2	1.0	1.0	1.2	0.9	1.0	1.2	1.2	-0.3
Intelligence (Savage-Jansen 2018)	0.9	2.7	6.7	-1.2	-1.2	-2.0	-2.3	-1.5	-1.7	-0.0	-2.4	-1.2	-1.3	-1.6	-1.4	-1.4	-1.2	-1.5	-1.7	-2.0	-2.6	-2.2
Fasting Glucose	0.9	1.1	3.6	-0.2	1.9	0.3	0.1	0.9	1.6	1.1	-0.0	-0.1	1.1	1.1	1.9	1.1	0.7	1.0	1.1	1.2	1.4	-0.9
Had menopause	0.9	1.1	3.3	-0.6	0.5	0.8	1.1	-1.8	0.4	1.7	-1.7	1.7	0.6	0.4	0.5	0.7	1.5	0.5	0.5	-0.1	-0.7	-1.5
Heart attack	0.9	1.1	2.9	-0.6	-0.9	-1.0	-1.2	0.2	-0.5	0.8	-0.9	-0.3	-1.1	-1.4	-1.1	-1.3	-1.3	-1.1	-1.0	-1.6	-1.7	-1.0
Medication: Lansoprazole	0.9	1.0	2.9	-0.1	1.5	1.7	1.1	-0.1	0.4	1.6	-0.2	0.9	0.8	1.1	1.2	1.1	1.2	0.8	0.9	0.9	0.9	-1.0
Length of working week for main job	0.9	1.0	11.5	1.1	0.6	-0.7	0.4	0.2	-0.1	3.4	1.3	-1.1	-0.1	-0.1	0.2	-0.1	-0.0	-0.0	-0.1	0.2	0.7	1.4
Leg fat percentage (right)	0.9	3.4	15.8	1.8	2.4	1.9	2.4	0.7	2.3	4.0	-1.0	0.8	1.6	1.7	2.4	1.9	2.2	1.3	2.0	0.4	0.8	-0.9
Pulse wave peak to peak time	0.9	1.1	3.7	-0.1	0.6	1.8	1.1	-0.8	1.0	-1.9	-0.1	1.9	1.0	0.9	1.0	0.9	1.0	1.0	0.8	1.1	0.4	-0.8
Illnesses of father: Heart disease	0.9	1.2	11.1	0.3	-0.2	0.1	1.1	-3.3	-0.8	1.4	-1.6	0.3	-0.5	-0.6	-0.8	-0.4	-0.2	-0.5	-0.6	-0.8	-1.4	-1.5
Diabetes diagnosed by doctor	0.9	1.5	3.3	-0.4	-1.4	-1.7	-0.9	-1.0	-1.8	-0.7	0.5	-1.5	-1.6	-1.4	-1.5	-1.5	-1.8	-1.5	-1.4	-0.1	-0.3	0.3
Leg fat percentage (left)	0.9	3.2	14.8	2.1	2.3	1.7	2.2	1.0	2.3	3.9	-1.0	0.8	1.5	1.6	2.4	1.7	2.1	1.2	1.9	0.4	0.7	-0.8
Number of operations (self-reported)	0.9	1.4	3.1	-0.6	-1.3	-0.1	-0.4	-1.3	-1.0	1.1	-1.1	-1.4	-1.5	-1.6	-1.0	-1.4	-1.1	-1.8	-1.3	-1.1	-1.5	-0.9
Pain experienced in last month	0.9	1.5	4.0	-0.2	0.7	1.7	2.0	-0.5	2.0	0.1	-0.3	1.7	1.3	1.5	1.4	1.5	1.7	1.0	1.5	1.0	0.4	0.2
Heart disease (siblings)	0.9	1.1	2.8	0.2	1.3	0.7	0.2	0.9	1.2	0.3	1.5	0.9	0.8	1.0	1.1	1.0	0.8	0.9	1.2	1.5	1.7	1.4
Hypothyroidism (self reported)	0.8	1.9	12.1	-0.1	-1.0	-0.2	-0.6	1.1	-0.7	0.0	2.8	-1.9	-1.0	-1.2	-0.8	-1.2	-0.8	-1.1	-1.2	1.4	1.5	3.5
Chronotype (morning person)	0.8	1.9	13.4	-1.9	-0.9	0.3	-1.0	1.4	-0.4	-2.0	2.8	-0.1	-0.5	-0.5	-0.8	-0.4	-0.2	-0.6	-0.5	1.1	1.6	3.7
Average weekly spirits intake	0.8	1.0	2.7	0.2	1.4	0.6	0.3	1.7	0.9	0.9	-0.0	0.4	1.1	1.0	1.4	1.1	1.1	1.2	1.2	1.3	0.8	-0.5
Average weekly fortified wine intake	0.8	1.0	3.3	1.1	1.3	0.8	0.8	0.7	0.7	1.0	-0.2	1.8	1.2	0.9	1.2	1.3	1.1	1.1	1.2	0.4	0.5	-0.7
Body mass index (BMI)	0.8	3.4	7.7	2.7	2.4	1.5	2.1	1.1	2.2	2.6	-0.7	0.7	1.9	2.0	2.8	2.1	2.3	1.6	2.2	0.7	0.9	-1.2
Arm fat percentage (right)	0.8	3.0	9.4	3.1	2.4	1.1	2.4	1.3	2.1	2.8	-0.9	0.9	1.4	1.6	2.5	1.6	2.0	1.1	1.7	0.2	0.6	-0.9
Illnesses of mother	0.8	0.9	4.4	1.7	0.7	1.2	1.6	-0.0	0.7	-0.9	-2.1	0.2	0.5	0.3	0.2	0.5	0.3	0.4	0.5	-0.3	-1.0	-1.8
Arm fat mass (right)	0.8	3.2	8.1	2.2	2.5	1.4	2.1	1.4	2.4	2.9	-0.4	0.7	1.7	1.9	2.8	1.9	2.3	1.4	2.0	0.5	1.0	-0.8
Pulse wave reflection index	0.8	1.0	3.0	-0.3	-1.0	-1.2	-1.7	1.6	-0.2	-0.5	-1.5	-1.2	-0.8	-0.8	-0.3	-0.7	-0.8	-0.7	-0.5	-1.1	-1.2	-1.1
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	3.8	-0.7	0.9	1.0	-0.0	0.4	0.6	-0.6	2.0	0.9	0.7	1.1	0.7	0.9	0.7	0.6	0.7	1.7	1.9	1.4
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.4	-0.4	-1.2	-1.3	-1.1	-0.0	-1.5	-1.3	0.9	-1.2	-1.0	-0.9	-1.1	-1.0	-1.3	-0.9	-1.0	-1.1	-0.4	0.3
Had major operations	0.8	0.9	4.3	-0.0	0.8	2.1	0.6	1.2	0.9	0.5	0.9	0.0	0.6	0.5	1.2	0.7	1.0	0.6	0.7	1.6	1.2	1.2
Illnesses of siblings: Diabetes	0.8	1.0	3.8	0.7	0.4	0.3	0.9	1.2	0.0	0.7	1.9	0.5	0.4	1.0	0.6	0.7	1.0	0.3	0.8	1.5	1.9	1.8
Handedness (chirality/laterality): Left-handed	0.8	0.9	4.9	1.5	-0.1	0.8	1.2	0.6	0.2	-1.0	1.8	0.1	0.3	0.7	0.6	0.5	0.1	0.2	0.6	1.0	1.6	2.2
Medication: Atorvastatin	0.8	1.0	2.5	0.4	1.2	0.9	0.4	-0.0	0.7	-0.9	-0.2	1.2	1.2	1.0	1.6	1.2	0.9	1.3	1.4	1.3	0.9	-0.1
Ovarian Cancer	0.7	0.9	3.6	-1.9	-0.5	-1.0	-1.3	-1.8	-1.2	-1.8	-0.7	0.4	-0.4	-0.4	-0.6	-0.4	-0.7	-0.3	-0.7	-0.3	-0.6	-0.2
Coronary Artery Disease (CAD)	0.7	0.9	4.2	-0.5	2.0	0.7	1.0	0.2	1.2	0.4	-0.6	1.2	1.0	1.2	1.0	1.1	1.0	1.0	1.1	0.0	0.2	0.0
BMI	0.7	3.8	8.4	2.5	2.7	1.7	2.1	1.6	2.4	2.8	-0.8	0.3	2.0	2.0	2.9	2.1	2.6	1.7	2.1	0.9	0.9	-1.3
Type 2 Diabetes (T2D) (2018)	0.7	1.4	4.6	-0.8	-1.2	-2.2	-1.1	-1.1	-1.6	0.2	1.1	-1.4	-1.4	-1.2	-1.3	-1.3	-1.5	-1.3	-1.1	-0.0	-0.0	0.9
Medication for hormone replacement therapy	0.7	0.8	2.2	-1.3	-0.7	0.5	-1.0	-0.1	-0.0	-1.0	-1.5	-0.4	-0.7	-0.9	-0.7	-0.8	-0.6	-0.8	-1.0	-1.2	-1.3	-1.4
Medication: Co-codamol	0.7	0.8	2.6	0.7	-0.7	0.0	-0.2	-1.6	-1.6	0.2	-0.6	-1.0	-1.1	-1.1	-1.2	-0.9	-0.9	-1.2	-1.2	0.1	-0.8	-0.6
Diabetes (father)	0.7	0.9	2.7	0.2	-1.5	-0.4	-0.4	-1.6	-1.0	-0.7	-1.6	-0.4	-0.8	-0.7	-0.8	-0.8	-1.0	-0.6	-0.8	-0.6	-1.1	-1.2
Pack years adult smoking proportion	0.7	1.1	2.9	1.4	1.1	0.5	1.6	1.7	1.1	1.3	1.0	0.5	1.1	0.9	1.0	1.0	0.8	1.4	1.2	0.7	1.0	0.7
Townsend deprivation index at recruitment	0.7	0.9	1.7	-0.5	-1.3	-0.8	-0.5	-1.3	-1.1	-0.7	-0.5	-0.5	-1.1	-1.2	-1.1	-1.1	-1.3	-1.2	-1.2	-1.2	-0.9	0.3
Stomach or abdominal pain in last month	0.7	0.9	3.5	-0.6	-0.9	-0.3	-0.9	-0.9	-1.9	-0.7	0.5	-1.3	-1.1	-0.7	-1.1	-1.0	-1.3	-1.0	-1.1	-0.6	0.1	0.9
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.1	-0.4	-1.1	-1.5	-1.2	0.5	-1.3	0.1	-0.8	-1.3	-0.9	-0.9	-1.2	-1.0	-1.0	-0.9	-1.0	-0.4	-0.7	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	5.3	-0.3	-0.3	-1.3	-2.3	0.9	-0.9	-1.3	-0.1	-1.6	-0.8	-0.9	-0.4	-1.0	-1.5	-0.9	-0.9	-1.0	-0.8	-1.0
Birth weight	0.7	1.6	5.5	-1.3	-1.1	0.2	-0.9	-0.7	-0.9	-0.8	-0.8	-2.0	-1.5	-1.5	-1.0	-1.5	-1.0	-1.6	-1.3	-2.4	-1.5	-1.2
Body fat percentage	0.7	2.9	13.5	2.7	2.0	1.4	2.4	1.2	2.2	3.7	-1.0	0.7	1.2	1.4	2.2	1.4	1.9	0.9	1.5	0.0	0.4	-0.8
Exposure to tobacco smoke outside home	0.7	1.0	2.5	0.9	-1.1	-0.7	-0.5	0.1	-1.6	-1.1	-1.0	-0.4	-1.1	-1.5	-1.1	-1.1	-1.1	-1.1	-1.0	-1.3	-1.1	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.5	-1.9	-1.1	-1.2	-1.1	-0.6	-0.6	0.1	0.8	-1.3	-1.0	-0.8	-0.8	-0.8	-0.9	-0.9	-0.8	-0.1	0.0	0.3
Medication: Seretide 50 evohaler	0.7	0.8	1.7	0.7	0.6	0.5	0.9	0.6	1.3	-1.0	0.8	0.8	1.2	1.2	0.9	1.0	0.6	1.3	1.0	0.7	1.1	0.6
Leg fat mass (right)	0.7	2.7	12.8	1.9	2.2	1.4	2.0	0.7	2.1	3.6	-0.8	0.2	1.4	1.4	2.3	1.6	1.9	1.1	1.7	0.1	0.6	-0.9
Arm fat percentage (left)	0.7	2.6	9.4	3.1	2.0	1.0	2.3	1.2	1.9	2.9	-1.1	0.6	1.1	1.4	2.3	1.4	1.8	0.8	1.4	-0.0	0.3	-1.1
Loneliness, isolation	0.7	0.9	2.9	0.6	0.9	1.5	-0.0	1.5	0.2	-1.4	1.1	0.2	1.0	0.8	0.7	0.9	0.9	1.0	0.8	1.2	1.7	0.3
Asthma (self-reported)	0.7	1.3	3.2	0.2	0.9	1.4	0.9	0.8	0.5	-1.6	0.1	0.6	1.6	1.8	1.4	1.8	1.1	1.6	1.6	1.0	1.2	-0.2
Smoking status: Current	0.7	1.1	6.4	1.2	1.2	1.7	1.1	2.5	0.6	0.1	0.9	0.5	0.9	0.6	0.6	0.9	0.9	1.0	1.0	1.3	0.9	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	4.7	-0.8	0.7	0.8	0.3	1.1	1.0	-1.0	1.4	0.9	1.2	1.3	1.6	1.3	1.5	1.1	1.3	2.0	2.2	1.1
Arm fat mass (left)	0.7	2.7	8.2	2.3	2.2	1.2	2.0	1.3	2.2	2.9	-0.7	0.3	1.4	1.6	2.5	1.7	2.0	1.1	1.7	0.3	0.7	-0.9
Pain type(s) experienced in last month: Hip pain	0.7	0.8	1.6	0.2	-0.7	-1.3	-1.1	0.3	-1.2	0.2	-0.6	-0.6	-1.2	-1.3	-1.2	-1.1	-0.9	-1.2	-1.1	-0.8	-1.1	-0.7
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.4	-0.9	-0.6	-0.9	-1.5	-0.6	-1.5	-0.6	0.3	-0.7	-1.0	-1.2	-1.4	-1.1	-0.8	-0.9	-1.2	-0.7	-0.6	0.2
Medication: Lisinopril	0.7	0.9	4.2	-1.5	0.2	-1.7	-0.6	-0.9	-1.4	2.0	0.1	-0.7	-0.7	-0.5	-0.9	-0.8	-0.7	-0.7	-1.1	0.2	-0.2	0.4
Myopia	0.7	1.0	2.5	1.6	0.9	1.2	1.4	1.1	1.0	1.5	1.0	-0.4	0.7	0.7	0.9	0.7	1.3	0.9	0.8	0.9	1.2	0.7
Leg fat mass (left)	0.7	2.8	11.9	1.9	2.3	1.3	2.0	1.1	2.2	3.5	-0.8	0.3	1.4	1.5	2.4	1.6	2.0	1.2	1.8	0.1	0.6	-0.9
Schizophrenia vs Biploar Disorder	0.6	0.7	2.4	1.1	-0.6	0.8	1.1	-1.1	-0.8	-1.6	-1.0	0.2	-0.6	-0.8	-0.9	-0.4	-0.4	-0.6	-0.6	-1.0	-1.5	0.0
Crohns Disease (2017)	0.6	1.2	5.5	-1.5	0.7	-0.7	-0.9	0.1	0.1	-0.4	1.8	-0.8	0.8	1.0	0.9	1.1	0.2	0.7	0.9	2.2	2.4	1.0
Reaction Time	0.6	1.1	4.4	-1.0	0.6	0.9	0.4	0.5	0.9	-0.7	2.1	0.5	0.9	1.4	1.3	1.2	0.7	0.8	1.0	1.1	1.8	0.7
Body Mass Index (BMI) (2010)	0.6	0.8	2.6	0.9	1.4	0.3	-0.0	0.3	1.6	0.3	-0.7	-0.1	0.9	1.1	1.3	1.0	0.9	1.0	1.0	-0.1	0.2	-1.5
Blood Eosinophil Count	0.6	4.9	31.7	-0.6	-1.5	-0.3	-1.8	2.2	-1.2	1.3	4.7	-2.4	-1.7	-1.5	-1.4	-1.8	-1.5	-1.6	-1.5	1.3	2.2	5.6
Systolic Blood Pressure	0.6	3.2	7.1	-0.1	-2.6	-2.7	-1.2	0.2	-1.8	-0.3	0.6	-1.4	-2.4	-2.4	-2.2	-2.4	-2.6	-2.1	-2.3	-1.3	-1.6	0.4
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.7	-0.3	-1.6	0.5	-0.4	-0.4	-0.4	-0.9	-1.6	0.3	-0.7	-1.0	-0.9	-0.8	-0.7	-0.7	-0.7	-1.0	-1.4	-1.3
Trunk fat percentage	0.6	2.6	10.0	2.7	1.9	1.3	2.3	1.3	2.2	3.2	-0.9	0.8	1.1	1.3	2.1	1.4	1.8	0.9	1.4	-0.1	0.3	-0.7
Maternal smoking around birth	0.6	0.8	3.4	-0.0	1.3	-0.1	-0.3	1.9	0.6	-0.1	0.3	0.2	1.2	1.0	1.1	0.9	0.6	1.3	1.2	1.5	1.0	-0.3
Qualifications: CSEs or equivalent	0.6	0.7	1.7	-0.3	-1.2	-0.8	-1.3	-1.1	-1.0	-0.3	-0.5	-1.2	-1.0	-1.0	-0.9	-0.9	-1.0	-1.0	-0.9	0.1	-0.7	-0.2
High blood pressure (mother)	0.6	0.8	4.8	-0.4	0.2	-1.1	-1.1	0.4	0.5	0.5	2.2	1.0	0.3	0.7	0.8	0.4	0.3	0.4	0.4	0.9	1.4	1.8
Trunk fat mass	0.6	2.5	10.6	2.2	2.1	1.2	2.1	1.3	2.2	3.3	-0.5	0.3	1.2	1.4	2.3	1.4	2.0	0.9	1.5	-0.0	0.6	-0.6
Number of incorrect matches in round	0.6	1.0	5.8	0.2	-0.3	-0.4	-0.4	1.9	0.4	-2.4	1.9	-0.5	-0.3	0.2	-0.3	-0.1	-0.6	0.1	0.2	1.4	1.0	1.4
Medication: Simvastatin	0.6	0.9	5.4	0.0	0.1	-0.0	0.8	-1.7	-0.4	1.1	-2.3	-0.6	-0.2	-0.2	-0.2	-0.1	-0.2	-0.2	-0.4	-1.1	-1.3	-1.8
Pulse rate	0.6	1.1	2.0	0.8	-1.2	-0.7	0.1	-1.4	-1.3	1.1	-0.9	-0.9	-1.1	-1.1	-1.1	-1.1	-1.0	-1.1	-1.2	-1.2	-1.4	-0.4
Exposure to tobacco smoke at home	0.6	0.7	5.1	-0.4	0.3	-0.7	-0.8	-1.1	0.1	-0.1	-2.3	0.5	-0.0	-0.0	0.2	0.1	-0.4	-0.2	0.0	-0.3	-1.3	-1.9
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	7.0	-1.1	0.2	0.3	-0.9	0.9	0.7	0.6	2.2	-0.6	0.3	0.1	0.4	0.2	0.4	0.2	0.0	1.9	1.9	2.6
Wheeze or whistling in the chest in last year	0.6	1.1	3.0	0.7	-0.9	-0.7	-1.0	0.4	-1.4	-0.0	-0.6	-1.6	-1.0	-1.2	-1.1	-1.0	-1.3	-0.9	-1.1	-1.7	-1.0	-1.2
Whole body fat mass	0.6	2.5	11.6	1.8	2.1	1.1	1.8	1.2	2.2	3.4	-0.6	0.3	1.3	1.4	2.3	1.5	1.9	1.0	1.6	0.2	0.7	-0.6
Suffer from ‘nerves’	0.6	0.9	4.1	-1.4	-0.8	-0.6	-1.6	0.4	-0.5	-1.9	2.0	-0.3	0.1	0.2	-0.3	-0.1	-0.3	0.2	-0.0	0.5	1.3	1.6
Commuting to job workplace: Car/motor vehicle	0.6	0.6	3.6	1.0	-0.4	0.3	1.2	-0.0	-0.1	-0.6	-1.9	0.6	0.1	0.0	0.1	0.2	0.7	-0.1	0.4	-1.0	-1.2	-1.7
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	5.1	-0.2	0.8	0.8	0.2	2.0	1.2	-1.2	2.2	0.3	0.6	0.9	0.8	0.6	0.9	0.5	0.6	1.0	1.6	2.3
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	4.0	-0.6	0.5	-1.2	-0.6	0.8	-0.6	-0.7	-0.4	-2.0	-0.7	-0.7	-0.3	-0.5	-1.1	-0.8	-0.4	-0.7	-0.1	-1.0
Medication: Gliclazide	0.6	0.7	3.1	0.4	-0.2	-0.9	-0.3	-1.3	-1.3	1.8	0.3	-1.1	-0.7	-1.2	-0.8	-0.8	-0.8	-0.7	-0.9	-0.6	-0.5	-0.2
Eye problems/disorders: Glaucoma	0.6	0.7	2.6	-0.9	-0.4	0.0	-0.6	-1.6	-1.0	-0.9	-1.0	-1.3	-0.5	-0.8	-0.7	-0.6	-0.9	-0.5	-0.7	-0.7	-0.7	-1.0
High cholesterol (Self-reported)	0.6	1.1	5.3	2.0	0.7	0.3	1.6	-1.6	-0.0	-0.3	-2.3	-0.2	0.5	0.1	0.4	0.4	-0.0	0.5	0.2	-0.5	-1.2	-1.9
Irritability	0.6	1.1	3.8	-1.1	-0.7	-1.4	-1.8	0.5	-1.2	-0.7	1.6	-1.2	-0.4	-0.4	-0.7	-0.4	-0.9	-0.3	-0.6	0.6	1.3	1.9
Pack years of smoking	0.6	0.9	2.3	1.3	1.2	0.1	1.5	1.4	1.1	1.3	0.6	0.5	1.1	0.9	0.9	1.0	0.7	1.4	1.1	0.6	0.8	0.4
Schizophrenia (2018)	0.5	1.0	4.8	2.2	0.4	1.8	2.1	-0.7	-0.3	-0.3	1.7	0.2	0.3	0.4	0.4	0.5	0.4	0.3	0.4	0.9	1.0	0.0
Irritable Bowel Disease (IBD)	0.5	1.2	5.1	-1.2	0.9	-0.9	-1.1	0.4	-0.3	0.9	2.1	-1.5	0.6	0.6	0.6	0.7	-0.1	0.5	0.5	2.0	2.3	1.2
Breast Cancer	0.5	1.3	3.6	-0.6	-0.7	0.2	-1.0	1.5	-1.5	-1.3	0.8	-0.9	-1.4	-1.5	-1.4	-1.3	-1.2	-1.6	-0.9	-0.3	-0.2	1.9
Frequency of depressed mood in last 2 weeks	0.5	0.7	4.3	0.7	0.5	1.6	0.1	1.5	-0.2	0.1	2.1	-0.5	0.6	0.5	0.3	0.4	0.1	0.6	0.3	0.2	1.4	0.8
Vitamin and mineral supplements	0.5	0.7	2.2	1.1	0.9	0.1	0.9	-0.1	1.2	-0.2	-0.9	1.5	0.8	1.2	0.8	0.9	0.7	0.7	0.9	0.3	-0.0	-0.8
Diabetes (mother)	0.5	0.7	1.8	-0.3	-0.9	-0.8	-0.9	-0.3	-1.0	0.4	0.3	-0.7	-1.1	-1.3	-0.7	-1.1	-1.0	-1.2	-0.9	-0.7	-0.3	0.9
Alcohol usually taken with meals	0.5	0.9	5.8	1.3	0.2	0.2	1.1	0.5	0.1	1.4	1.9	0.5	-0.5	-0.1	-0.6	-0.5	0.2	-0.8	-0.5	0.3	0.7	2.4
Pain all over the body in last month	0.5	0.5	5.4	2.3	0.0	0.5	0.3	1.7	-0.4	-0.2	-0.0	-0.9	-0.2	-0.2	0.2	-0.2	-0.4	-0.2	0.1	0.2	0.1	-0.3
Hair/balding pattern: Pattern 3	0.5	0.7	3.5	0.9	0.3	1.2	1.5	0.2	0.4	0.1	1.4	0.7	0.4	0.7	0.3	0.5	0.2	0.2	0.5	0.8	1.2	1.9
Qualifications: A levels/AS levels or equivalent	0.5	1.0	5.3	-1.1	-0.5	-0.6	-0.3	-1.5	-0.4	-2.3	-1.3	-0.6	-0.6	-0.6	-0.5	-0.6	0.3	-0.8	-0.7	-1.3	-1.0	-1.8
Asthma	0.5	1.0	2.6	0.2	0.8	1.3	0.9	0.5	0.3	-1.6	-0.3	0.6	1.4	1.5	1.1	1.5	0.9	1.4	1.3	0.6	0.8	-0.6
Tense / ‘highly strung’	0.5	0.8	5.1	-1.1	-0.1	0.4	-1.0	0.6	-0.8	-0.5	2.3	-0.4	0.0	0.1	-0.4	-0.0	-0.3	0.3	-0.2	1.1	1.9	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.4	-1.3	0.1	-1.0	-1.1	-0.6	-0.9	-0.8	-1.6	-1.3	-0.5	-0.6	-0.3	-0.4	-1.0	-0.6	-0.4	-1.0	-0.5	-0.8
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.9	-0.8	-0.1	-0.8	-1.0	0.7	0.2	1.0	-1.5	-0.8	-0.4	-0.5	-0.2	-0.5	0.1	-0.5	-0.5	-0.5	-0.8	-2.0
Glaucoma (self-reported)	0.5	0.6	4.0	-0.2	1.1	-0.1	0.2	-2.0	-0.3	0.4	-1.0	-0.6	0.8	0.6	0.4	0.7	0.2	0.9	0.6	0.3	0.3	-1.1
Medication: Ventolin 100micrograms inhaler	0.5	0.6	2.5	1.6	-0.6	-1.3	-0.2	0.5	-1.2	0.1	0.3	-1.2	-0.6	-0.7	-1.0	-0.7	-1.1	-0.4	-0.7	-0.8	-0.0	0.2
Comparative body size at age 10	0.5	1.4	4.1	0.8	1.0	1.1	2.0	-0.5	1.1	0.5	-1.4	1.5	1.2	1.3	1.4	1.4	1.7	0.9	1.5	-0.0	0.1	-1.1
Migraine (self-reported)	0.5	0.6	2.1	0.4	1.2	1.5	0.9	-0.3	0.6	-0.8	-0.8	-0.1	0.7	0.3	1.0	0.6	0.9	0.8	0.6	0.7	0.0	-1.0
Smoking status: Previous	0.5	0.7	2.3	-1.2	-0.3	-0.9	-1.0	-1.2	-0.4	-0.7	-1.5	-0.1	-0.4	-0.6	-0.7	-0.4	-0.7	-0.4	-0.4	-0.9	-1.4	-1.2
Average weekly red wine intake	0.5	0.7	3.3	1.4	-0.3	0.2	1.0	-1.1	0.6	-0.3	-1.8	-0.5	-0.3	-0.4	-0.2	-0.3	-0.2	-0.8	-0.2	-1.4	-1.4	-0.9
Mood swings	0.5	1.0	3.5	-0.3	-0.7	-0.9	-1.1	-0.2	-1.9	-0.4	1.4	-1.8	-0.9	-1.0	-1.0	-1.0	-1.5	-0.6	-1.1	0.1	0.5	0.8
Long-standing illness, disability or infirmity	0.5	0.7	2.5	-0.5	-1.0	-1.4	-1.3	-0.1	-0.8	-0.4	-0.6	-0.4	-0.7	-0.8	-1.0	-0.8	-1.6	-0.7	-0.9	-0.7	-0.8	-0.5
Qualifications: nursing, teaching	0.5	0.8	2.6	-0.6	1.1	-0.1	-0.1	0.3	1.2	-0.2	-0.7	0.6	1.1	1.2	0.9	1.1	1.4	0.9	1.0	-0.0	0.5	-1.6
Back pain experienced in last month	0.5	0.8	2.2	1.3	-1.1	-0.3	-0.6	0.1	-1.5	0.4	0.2	-0.1	-1.0	-1.0	-1.5	-1.1	-0.9	-1.0	-1.3	-0.7	-0.5	0.4
Average weekly champagne plus white wine intake	0.5	0.7	3.4	0.1	-1.2	0.9	1.2	-0.2	-0.1	0.7	1.3	0.5	0.1	0.4	-0.2	0.1	1.1	-0.3	0.0	1.0	1.3	1.8
Ever smoked	0.5	0.8	2.1	-0.6	1.1	0.8	0.2	0.9	1.0	-0.4	-1.4	0.7	1.2	0.8	0.8	1.1	1.0	1.2	1.2	0.2	-0.2	-1.1
Unable to work because of sickness or disability	0.5	0.6	3.8	-0.4	-0.1	-0.9	-1.5	0.6	-1.1	-1.9	0.2	-1.2	-0.1	-0.8	-0.5	-0.5	-1.0	0.0	-0.5	-0.1	-0.4	-0.0
Supplements: Calcium	0.5	0.5	3.2	-0.9	0.1	0.5	-0.3	0.5	0.4	0.3	0.6	0.4	0.8	0.7	0.4	0.9	0.6	0.8	0.6	1.8	0.9	0.5
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.7	-0.3	-0.5	-0.6	-0.8	0.3	-0.3	0.9	-0.7	-0.1	-0.8	-1.1	-0.7	-1.0	-0.9	-0.7	-0.6	-1.3	-1.3	-0.9
Alzheimer’s Disease (in father)	0.4	0.4	1.5	-0.6	-0.2	0.1	-1.1	0.1	0.5	-0.1	1.2	-1.0	0.2	0.5	0.3	0.3	0.3	0.2	0.4	1.0	1.1	1.0
Alzheimer’s Disease (including proxy)	0.4	0.5	1.6	-0.3	0.7	1.0	0.6	-0.2	0.3	-0.0	1.3	0.2	0.6	1.1	0.7	0.7	0.9	0.7	0.4	0.9	1.2	0.5
Ulcerative Colitis (UC)	0.4	0.8	3.5	-0.2	0.5	-1.1	-1.3	1.3	-0.3	1.1	1.5	-1.9	-0.1	-0.2	-0.1	-0.1	-0.7	-0.0	-0.0	0.7	1.1	0.9
Mean Putamen Volume	0.4	0.5	1.7	-1.3	-1.1	-0.4	-1.3	-0.1	-0.1	-0.9	0.1	-0.3	-0.7	-0.7	-0.8	-0.7	-0.6	-0.6	-0.9	-0.8	-0.6	0.0
Primary Biliary Cirrhosis	0.4	0.6	1.8	-0.5	-0.1	1.2	0.0	-0.0	0.3	-1.3	1.3	0.8	0.7	0.8	0.5	0.6	0.8	0.7	0.7	0.9	1.3	0.0
Triglycerides	0.4	0.6	3.0	-1.7	0.7	-1.3	-1.0	-0.6	-1.1	-0.6	0.2	-0.8	-0.7	-0.5	-0.4	-0.7	-1.0	-0.6	-0.7	-0.2	-0.2	0.0
Heel T-Score	0.4	3.3	9.7	-3.1	-2.5	-1.7	-2.5	0.2	-1.0	0.0	0.7	-1.4	-2.3	-1.9	-2.5	-2.1	-1.4	-2.4	-2.0	-1.5	-0.7	1.7
Waist Hip Ratio (WHR)	0.4	1.9	8.3	-2.9	-1.8	-1.0	-1.2	-0.1	-1.3	-0.4	-0.7	-0.6	-1.6	-1.5	-1.8	-1.5	-1.5	-1.7	-1.4	-0.9	-1.3	0.1
Lung FEV1/FVC ratio	0.4	2.0	5.2	0.1	1.4	1.3	1.6	-0.4	2.3	2.2	0.2	1.0	1.3	1.6	1.9	1.5	2.3	1.1	1.4	0.9	1.5	-0.5
Lung FVC	0.4	1.9	8.7	-1.3	1.3	0.8	0.3	-0.4	0.6	-2.9	-1.7	1.6	1.5	1.2	1.2	1.4	1.2	1.5	1.4	0.5	-0.2	-2.4
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.3	0.9	-1.1	0.6	0.7	0.1	-0.5	-0.6	-0.6	1.0	-0.4	-0.7	-0.8	-0.6	-0.3	-0.5	-0.5	-0.3	-0.9	-0.3
Illnesses of siblings	0.4	0.5	3.0	-0.3	-0.7	0.8	0.9	-0.4	0.7	-0.7	-1.7	0.5	0.3	0.2	-0.1	0.2	0.2	0.0	0.2	-0.9	-1.1	-1.3
Weight	0.4	2.1	7.6	1.5	2.2	1.1	1.8	0.8	1.9	2.8	-0.3	-0.0	1.3	1.4	2.2	1.5	2.0	1.0	1.6	0.1	0.7	-0.7
Hip circumference	0.4	1.8	4.9	2.2	1.9	1.0	1.7	1.0	1.8	2.2	0.3	0.3	1.2	1.4	1.8	1.3	1.9	0.9	1.3	0.1	1.0	-0.1
Time employed in main current job	0.4	0.4	2.2	0.8	-0.0	-0.9	-0.2	0.6	-0.3	1.5	-0.3	-0.8	-0.3	-0.6	-0.7	-0.5	-0.5	-0.1	-0.5	-1.1	-0.7	-0.4
Depression (self-reported)	0.4	0.5	4.1	0.3	0.4	0.4	-0.0	0.5	-0.0	-2.0	0.5	-0.6	0.9	0.8	0.6	0.6	0.2	1.0	0.8	0.2	1.0	0.1
Breastfed as a baby	0.4	0.5	2.5	0.1	-1.6	0.2	-0.4	0.5	0.2	0.6	0.6	-0.8	-0.9	-0.5	-0.4	-0.8	-0.1	-1.2	-0.7	-1.3	-0.2	0.9
Birth weight of first child	0.4	0.8	4.0	0.1	-0.1	0.3	0.0	-0.5	-0.3	-1.2	-1.6	-0.1	-0.5	-0.8	-0.3	-0.6	-0.7	-0.4	-0.5	-1.4	-2.0	-1.9
Medication: Paracetamol	0.4	0.7	3.4	1.8	0.2	-0.4	-1.2	1.6	-0.1	-1.4	-1.1	-0.4	-0.6	-0.9	-0.1	-0.6	-0.8	-0.5	-0.3	-0.2	-0.7	-0.9
Forced vital capacity (FVC), Best measure	0.4	1.5	5.8	-1.9	1.5	0.4	0.3	-0.1	0.8	-2.4	-0.6	0.9	1.6	1.3	1.4	1.5	1.4	1.4	1.4	0.9	0.5	-0.7
Number of children fathered	0.4	0.5	1.9	-1.1	-0.3	-0.5	-0.8	-0.2	0.8	0.1	-1.0	1.0	0.3	-0.0	-0.2	0.1	0.4	0.2	0.2	-1.1	-0.9	-1.4
Eye problems/disorders: None of the above	0.4	0.5	4.6	2.1	-0.0	-0.7	0.6	0.9	0.4	-0.3	0.0	1.3	-0.2	0.1	-0.1	-0.1	-0.2	-0.4	0.3	0.2	-0.3	0.6
Mouth/teeth dental problems: Loose teeth	0.4	0.5	2.3	-1.5	0.2	-0.6	-0.9	-0.9	0.3	1.3	1.0	1.1	0.1	0.3	0.5	0.3	0.1	0.2	0.2	0.5	0.8	0.7
Medication for pain relief, constipation, heartburn	0.4	0.6	3.9	-1.2	-0.2	0.7	1.5	-2.0	0.2	0.7	1.1	0.6	-0.0	0.5	-0.3	0.2	0.4	-0.2	-0.3	-0.5	0.1	1.3
Angina (self-reported)	0.4	0.5	3.6	-0.1	-0.1	-0.5	-0.3	-0.3	-0.5	0.3	-1.9	0.0	-0.6	-0.8	-0.3	-0.5	-0.6	-0.7	-0.5	-0.5	-1.3	-1.3
Pulse rate, automated reading	0.4	1.2	3.8	1.1	-0.6	-1.5	0.3	-0.8	-1.9	1.1	0.8	-0.9	-1.2	-1.1	-1.5	-1.1	-1.1	-1.2	-1.2	-0.6	-0.4	1.4
Chest pain or discomfort	0.4	0.5	1.9	-0.3	-0.2	-1.4	-1.1	0.6	-0.6	1.3	1.0	-0.7	-0.5	-0.5	-0.4	-0.6	-1.0	-0.4	-0.6	0.5	0.6	0.7
Medication: Aspirin	0.4	0.5	1.8	1.2	0.6	-0.9	-0.5	1.3	-0.6	0.6	-1.1	-0.5	-0.3	-0.7	-0.2	-0.5	-0.6	-0.2	-0.2	-0.3	-0.7	-1.2
Medication: Aspirin	0.4	0.5	2.1	0.8	0.6	-0.9	-0.4	1.5	-0.5	0.8	-1.0	-0.2	-0.2	-0.8	-0.1	-0.5	-0.6	-0.1	-0.2	-0.3	-0.7	-1.0
Miserableness	0.4	0.7	1.5	1.1	-0.9	-1.0	-0.7	-0.2	-1.0	-1.2	1.0	-0.7	-0.7	-0.8	-0.9	-0.8	-1.1	-0.6	-0.9	-0.5	-0.1	0.7
Guilty feelings	0.4	0.5	1.6	-0.2	0.9	-0.4	-0.1	-1.3	0.2	-0.3	0.6	0.9	0.8	0.7	1.0	0.8	0.7	0.9	0.5	1.2	1.1	0.1
Hearing aid user	0.4	0.5	3.0	-1.7	0.5	-0.8	-1.4	0.6	0.2	0.0	0.4	-0.8	-0.0	-0.1	0.1	0.0	0.2	-0.1	0.0	0.5	0.8	1.0
Medication: Paracetamol	0.4	0.6	6.5	2.5	0.7	-0.4	-0.3	1.7	-0.0	-1.0	-0.5	0.0	-0.2	-0.4	0.2	-0.2	-0.4	-0.1	0.2	0.1	-0.2	-0.5
Diastolic blood pressure, automated reading	0.4	1.1	6.8	-1.3	-0.4	-2.6	-1.6	-0.7	-0.3	1.5	-0.8	-0.8	-0.9	-0.7	-0.4	-0.6	-0.8	-0.7	-0.8	-0.6	-0.9	-1.3
Depression (Nagel 2018)	0.3	0.4	2.6	0.7	-0.4	0.0	-0.3	0.5	-0.9	0.1	0.7	-1.6	-0.5	-0.4	-0.7	-0.6	-0.7	-0.6	-0.5	-1.0	-0.2	0.0
Neuroticism (Nagel 2018)	0.3	0.6	3.8	-0.7	-0.4	-1.3	-2.0	-0.4	-1.1	-1.2	0.4	-0.7	-0.5	-0.5	-0.5	-0.4	-1.1	-0.4	-0.5	-0.2	-0.2	-0.4
HDL Cholesterol	0.3	0.4	1.6	1.0	-0.0	-0.5	0.5	-1.2	0.2	0.8	-1.3	1.2	-0.0	0.1	-0.2	0.1	0.4	-0.1	0.2	-1.0	-1.0	0.0
Schizophrenia (2014)	0.3	0.7	4.0	1.8	0.1	1.3	2.0	-1.3	0.0	-0.5	0.7	0.3	0.3	0.5	0.6	0.5	0.4	0.3	0.3	0.9	0.8	0.0
Blood Platelet Count	0.3	3.8	33.8	-0.2	-2.2	-0.3	-0.3	-0.8	-1.4	0.6	4.7	-1.3	-0.7	-0.2	-1.4	-0.8	-0.7	-0.8	-0.8	0.7	2.3	5.8
Neuroticism	0.3	0.7	3.8	-0.7	0.6	-0.6	-1.5	-0.2	0.1	-2.0	0.6	0.2	1.0	1.0	0.7	1.0	0.2	1.0	0.8	0.5	1.0	-0.6
Hearing difficulty/problems: Yes	0.3	0.4	3.5	-1.1	0.3	-0.5	-1.4	1.9	0.8	-0.2	0.4	-0.7	-0.0	-0.4	-0.1	-0.2	0.3	-0.2	0.1	-0.2	0.1	0.0
Supplements: Zinc	0.3	0.3	1.4	-0.9	-1.2	0.7	-0.1	0.2	-0.7	0.4	0.4	-0.3	-0.4	-0.5	-0.6	-0.3	-0.3	-0.3	-0.5	-0.3	-0.0	0.9
Hand grip strength (right)	0.3	0.8	3.3	-1.8	1.6	-0.4	-0.3	-0.7	0.9	0.4	-0.4	0.1	0.9	0.9	1.2	1.0	0.7	0.9	1.1	0.4	0.0	-1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.3	2.3	0.3	-0.4	0.0	-0.7	0.5	-1.0	-0.6	1.0	-1.5	-0.2	-0.3	-0.5	-0.3	-0.6	-0.3	-0.1	-0.4	0.5	0.4
Age when periods started (menarche)	0.3	0.7	4.4	-1.5	-0.5	-0.3	-0.3	-2.1	-0.8	0.1	-0.1	-0.8	-0.5	-0.9	-0.9	-0.9	-0.7	-0.5	-0.9	-0.3	-0.6	-0.6
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	2.4	1.2	0.6	0.7	0.5	0.1	-0.4	1.5	0.1	-0.2	-0.1	-0.2	0.1	0.0	0.3	-0.1	-0.0	0.4	0.2	0.4
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.4	0.0	-1.0	0.3	-0.5	-0.4	-0.6	-0.2	-0.5	-0.7	-1.0	-0.7	-1.1	-0.8	-0.8	-1.2	-0.7	-1.2	-1.6	-0.4
Supplements: Glucosamine	0.3	0.4	2.0	-0.3	0.1	0.9	-0.0	0.3	0.1	0.7	1.4	0.7	0.2	-0.1	0.5	0.1	0.4	0.3	0.1	0.8	1.3	1.0
Hair/balding pattern: Pattern 2	0.3	0.4	3.5	-0.3	-0.5	-0.5	-0.9	1.9	0.4	0.4	0.6	-0.5	-0.6	-0.7	-0.2	-0.7	-0.2	-0.5	-0.3	0.4	-0.1	0.2
Forced vital capacity (FVC)	0.3	1.1	6.2	-1.3	0.8	0.9	0.6	-0.2	0.5	-2.5	-1.0	0.9	1.2	1.1	0.9	1.2	1.3	0.9	1.1	0.6	0.2	-0.7
Medication: Ramipril	0.3	0.4	1.1	0.7	1.0	0.1	0.5	1.0	0.0	1.1	0.6	0.9	0.4	0.3	0.4	0.3	0.7	0.6	0.3	0.8	0.0	0.7
Neuroticism score	0.3	0.6	3.2	-0.4	0.3	-0.2	-1.3	-0.1	-0.4	-1.3	1.8	-0.1	0.6	0.7	0.3	0.5	-0.1	0.7	0.3	1.1	1.5	0.6
Worrier / anxious feelings	0.3	0.5	1.9	-0.6	0.1	-1.0	-1.4	0.0	-0.7	-1.3	1.3	-0.2	-0.4	-0.1	-0.3	-0.4	-1.2	-0.3	-0.5	0.4	0.2	0.5
Falls in the last year	0.3	0.4	1.1	0.9	0.9	-0.3	-0.1	0.6	-0.2	0.0	-0.2	0.2	1.0	0.8	0.4	0.9	0.6	1.0	0.8	1.0	0.8	0.2
Number of live births	0.3	0.5	3.4	0.8	0.1	1.1	1.8	-0.7	-1.0	0.1	0.9	-0.5	-0.0	-0.3	-0.1	-0.0	0.1	0.1	-0.0	0.7	0.7	0.6
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	4.0	-0.9	0.8	1.1	1.0	-0.4	0.9	-2.0	-0.9	1.0	1.2	1.3	1.3	1.4	1.6	0.9	1.3	0.7	0.4	-0.6
Prospective memory result	0.3	0.4	2.1	-0.9	0.6	-1.0	-1.4	1.5	0.2	0.6	-0.1	-0.5	0.0	-0.1	0.3	0.1	-0.4	0.3	0.1	0.8	0.2	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	3.0	-1.7	1.1	0.4	0.5	-0.2	0.9	-1.7	-0.6	0.8	1.2	1.2	1.3	1.3	1.5	1.1	1.2	0.8	0.5	-0.7
Impedance of arm (left)	0.3	1.4	3.4	1.4	-1.4	-0.5	0.5	-0.3	-1.2	-0.9	-0.6	-0.1	-1.6	-1.4	-1.7	-1.6	-1.5	-1.6	-1.9	-1.0	-1.3	0.6
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.1	-1.5	-1.1	-0.1	-0.2	-1.3	-0.0	-1.3	-0.5	0.5	-0.3	-0.1	-0.5	-0.2	0.1	-0.6	-0.3	0.1	-0.4	-0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.8	0.7	0.1	1.3	0.8	0.7	1.3	0.4	-0.1	0.5	0.7	0.9	0.7	0.9	1.2	0.5	0.8	0.3	0.4	-0.2
Medication: Amlodipine	0.3	0.4	3.1	-0.4	-0.2	-0.7	-0.5	1.2	0.2	-1.8	0.7	-0.6	-0.2	-0.2	0.2	-0.2	-0.5	-0.1	-0.1	0.5	0.3	0.8
Number of full brothers	0.3	0.4	1.3	-0.0	-0.4	-0.6	0.0	-0.9	-0.6	1.1	0.4	0.6	-0.7	-0.5	-0.8	-0.5	-0.4	-0.7	-0.2	0.3	0.1	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.8	-0.4	0.7	-0.1	0.1	-1.3	-0.6	1.2	-1.0	0.1	0.0	0.1	-0.1	0.2	-0.0	-0.1	0.0	-0.5	-0.7	-0.6
Eye problems/disorders: Cataract	0.3	0.4	2.3	-1.5	0.1	-0.1	-0.7	-0.1	0.5	-0.8	-0.9	0.3	0.1	-0.0	0.3	0.0	0.0	0.3	-0.1	-0.6	-0.3	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.7	-0.4	-1.6	0.2	-0.8	-1.0	-1.2	-0.5	-0.4	0.2	-0.3	-0.4	-1.0	-0.5	-0.7	-0.3	-0.4	-0.7	-0.5	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.3	-0.8	0.6	0.3	-0.9	0.3	-0.5	0.1	-1.1	-0.7	0.5	0.1	0.3	0.4	0.7	0.5	0.4	0.1	0.1	-1.0
Breast cancer (self-reported)	0.3	0.3	1.0	0.6	-0.5	-0.3	0.8	-0.8	-0.7	0.6	0.8	0.4	-0.4	-0.3	-0.8	-0.4	-0.4	-0.4	-0.5	-1.0	-0.2	-0.3
Osteoarthritis (self-reported)	0.3	0.4	3.8	0.2	-0.4	-0.2	-0.5	-0.5	-0.5	2.0	0.6	-0.2	-0.4	-0.5	-0.6	-0.5	-0.8	-0.3	-0.3	0.1	-0.3	-0.2
Illnesses of father: None of the above (group 1)	0.3	0.3	0.9	0.3	-0.7	-0.2	0.2	0.5	-0.6	1.0	0.5	-0.6	-0.7	-0.8	-0.8	-0.6	-0.6	-0.7	-0.5	-0.3	0.1	0.8
Number of self-reported non-cancer illnesses	0.3	0.5	1.4	-0.1	-0.1	-0.8	-0.3	-1.0	-0.5	0.9	-1.2	-0.8	-0.4	-0.4	-0.6	-0.5	-0.7	-0.3	-0.4	-0.9	-1.1	-0.8
Risk taking	0.3	0.5	1.2	-0.0	-1.1	-0.7	0.3	-0.3	-0.6	-0.5	-0.2	-1.1	-0.8	-0.9	-1.0	-0.7	-0.9	-0.8	-0.7	-0.4	-0.1	0.9
Ever had prostate specific antigen (PSA) test	0.3	0.4	2.5	0.3	0.7	-0.5	0.1	-1.0	-0.4	0.4	-1.0	-1.0	-0.1	-0.4	0.1	-0.2	-0.5	-0.1	-0.1	-0.5	-0.3	-1.6
Age at First Birth	0.2	0.3	2.0	0.3	-0.2	0.9	1.4	-0.9	0.6	0.5	-0.1	0.5	0.4	0.4	0.0	0.4	0.5	0.5	0.3	-0.3	-0.1	0.7
Crohns Disease (2012)	0.2	0.3	1.4	-0.8	-0.7	-1.2	-0.4	-0.9	-0.5	0.5	1.0	-0.0	-0.3	-0.1	-0.3	-0.2	-0.4	-0.3	-0.3	0.6	0.9	0.0
Neuroticism (2016)	0.2	0.3	1.2	-1.0	0.1	-0.2	-1.0	0.6	0.1	-0.6	0.0	0.8	0.4	0.1	0.2	0.3	0.1	0.4	0.5	1.1	0.5	0.0
Blood White Count	0.2	1.2	7.4	-2.3	-1.3	0.0	-0.9	0.5	0.3	2.1	1.5	-0.5	-0.5	-0.4	-0.2	-0.7	-0.4	-0.5	-0.5	0.2	0.9	2.7
Height	0.2	3.0	7.1	-2.7	-1.1	-0.7	-0.7	0.4	-0.9	1.1	1.6	-2.2	-2.2	-2.2	-1.9	-2.1	-1.1	-2.4	-2.1	-2.3	-0.8	2.5
Hair Pigment	0.2	5.0	48.3	6.9	0.8	1.3	4.0	1.4	0.5	-1.3	0.7	2.1	1.8	1.9	1.7	1.8	1.5	1.9	1.7	1.2	1.0	0.2
Hand grip strength (left)	0.2	0.6	5.5	-2.3	0.3	-1.4	-1.8	-0.2	0.1	-0.7	0.2	-0.8	-0.3	-0.1	-0.1	-0.1	-0.5	-0.2	-0.0	-0.5	-0.3	-0.3
Sensitivity / hurt feelings	0.2	0.3	1.3	-0.4	-0.6	-0.5	-1.1	-1.1	-0.6	-0.4	-0.1	-0.5	-0.3	-0.1	-0.5	-0.1	-0.8	-0.3	-0.3	-0.2	-0.1	-0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.3	-1.1	0.1	-0.4	-0.7	-1.0	-0.5	0.8	-0.3	-1.0	-0.2	-0.2	-0.4	-0.3	-0.3	-0.4	-0.4	-0.4	-0.0	-0.0
Angina	0.2	0.3	2.5	-0.1	0.2	-0.3	-0.2	-0.0	-0.4	0.5	-1.6	0.2	-0.4	-0.6	-0.1	-0.3	-0.4	-0.5	-0.3	-0.1	-0.9	-1.1
Severe depression (siblings)	0.2	0.3	2.3	1.5	0.3	0.2	0.8	-0.1	-0.1	0.1	0.1	0.1	0.4	0.3	0.6	0.4	0.4	0.4	0.4	0.4	0.3	-0.7
Relative age voice broke	0.2	0.2	1.1	-1.1	-0.3	0.8	0.1	-0.5	0.3	-0.2	0.7	-0.8	0.1	0.0	0.4	0.2	-0.1	-0.0	0.1	0.7	0.7	0.2
Multivitamins +/- minerals	0.2	0.2	0.7	-0.4	0.1	-0.8	-0.6	0.6	-0.8	0.3	0.1	-0.7	-0.1	-0.7	-0.2	-0.3	-0.2	0.1	-0.2	0.2	0.1	0.3
Medication: Atenolol	0.2	0.3	2.0	0.6	0.6	1.1	-0.1	0.9	0.2	-1.4	0.1	0.1	0.3	0.4	0.5	0.3	0.3	0.2	0.7	0.3	0.0	-0.2
Waist circumference	0.2	0.9	5.3	0.8	1.2	0.8	1.1	0.8	1.3	2.3	-0.5	0.1	0.6	0.8	1.2	0.8	1.2	0.3	0.9	-0.2	0.2	-0.8
Past tobacco smoking	0.2	0.4	2.9	0.7	-0.5	-0.1	0.1	0.5	-0.4	0.3	1.7	-0.6	-0.5	-0.2	-0.2	-0.5	-0.3	-0.5	-0.5	0.4	1.0	1.3
Nervous feelings	0.2	0.4	4.2	-0.9	-0.6	-0.2	-1.0	-0.6	-0.4	-2.1	0.5	0.5	0.4	0.7	-0.0	0.4	-0.0	0.4	0.3	0.2	0.6	0.1
Qualifications: None of the above	0.2	0.3	2.1	-0.6	-0.4	0.5	-0.1	0.1	-1.0	-1.4	0.3	-0.3	-0.6	-0.7	-0.6	-0.5	-0.8	-0.4	-0.5	0.4	0.1	0.4
Mouth/teeth dental problems	0.2	0.3	1.8	0.1	1.0	-0.3	0.4	0.1	1.3	0.4	0.6	-1.0	0.4	0.5	0.8	0.4	0.6	0.5	0.4	0.1	0.4	0.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.5	1.6	0.4	0.4	0.8	-0.2	-0.1	0.7	0.5	-0.3	0.5	0.5	-0.2	0.5	-0.1	0.3	0.4	0.0	0.1	0.8
Fluid intelligence score	0.2	0.4	1.5	-1.0	-0.5	-0.8	-1.1	-0.1	-0.5	-0.8	-0.7	-1.2	-0.3	-0.6	-0.2	-0.4	0.1	-0.3	-0.5	-0.4	-0.3	-0.5
Impedance of arm (right)	0.2	1.0	2.3	1.4	-0.9	-0.2	0.8	0.1	-0.9	-0.9	0.2	0.3	-1.3	-1.2	-1.3	-1.3	-1.1	-1.2	-1.5	-0.8	-0.8	1.2
Mouth/teeth dental problems: Dentures	0.2	0.3	1.5	0.6	-0.0	-0.3	-0.1	1.2	-1.0	0.1	-0.8	0.5	-0.5	-0.7	-0.3	-0.4	-0.2	-0.3	-0.3	0.0	-0.4	-0.5
Medication: Cholesterol lowering	0.2	0.3	1.9	0.8	0.9	0.2	0.7	-1.0	-0.4	-0.1	-1.0	0.2	0.3	-0.0	0.4	0.1	-0.2	0.4	0.1	-0.2	-0.2	-1.4
Lung cancer (father)	0.2	0.2	1.2	-0.1	1.1	-0.9	-0.1	-0.6	-0.6	0.7	0.1	-0.1	0.1	0.1	0.1	0.2	-0.4	0.2	0.2	-0.3	0.1	-0.5
Hair/balding pattern: Pattern 4	0.2	0.6	2.6	0.3	-0.9	-0.9	0.2	-1.1	-0.5	0.2	-1.6	0.0	-0.2	-0.1	-0.3	-0.2	-0.5	-0.0	-0.5	-1.4	-1.1	-1.4
Blood clot in the leg (DVT)	0.2	0.2	1.2	1.1	0.4	-0.5	0.4	0.6	0.2	0.3	-0.6	0.4	0.1	-0.0	0.4	0.2	0.1	0.1	0.3	0.5	-0.2	-0.8
Arm fat-free mass (right)	0.2	0.8	1.8	-1.2	1.2	0.6	-0.1	0.4	1.3	1.3	0.6	-0.8	0.9	0.8	1.3	0.9	1.3	0.7	1.1	0.2	0.9	-0.1
Age at first live birth	0.2	0.3	1.1	-0.4	0.2	-0.1	0.4	0.0	1.1	-1.0	-0.4	0.4	0.4	0.6	0.6	0.4	0.6	0.3	0.5	-0.6	-0.2	-0.7
Shortness of breath walking on level ground	0.2	0.2	1.7	1.3	-0.1	-0.3	0.5	0.6	-1.0	-0.2	0.3	-0.2	-0.1	-0.2	-0.3	-0.2	-0.3	-0.1	-0.2	0.2	0.4	0.2
Qualifications: College or University degree	0.2	0.8	2.6	0.1	0.7	-0.0	1.6	-1.6	0.6	0.9	-0.1	0.9	1.0	1.1	0.9	0.8	1.4	0.7	0.9	0.5	0.5	0.3
Mean time to correctly identify matches	0.2	0.3	0.9	-0.3	0.5	0.7	0.8	0.2	0.7	0.7	0.8	1.0	0.4	0.7	0.7	0.6	0.5	0.2	0.4	0.2	0.4	-0.2
Alcohol intake frequency.	0.2	0.5	4.6	2.1	-0.1	0.3	1.1	0.7	-0.2	1.0	0.8	-0.0	-0.3	-0.1	-0.1	-0.2	-0.0	-0.2	-0.1	0.5	0.4	1.3
Number of full sisters	0.2	0.2	2.2	0.0	-0.5	-0.4	-0.2	0.6	0.3	-0.2	-0.7	-0.7	-0.2	-0.0	0.2	-0.2	-0.3	-0.1	0.1	-0.4	-0.2	-1.5
Overall health rating	0.2	0.5	3.5	1.9	-0.0	0.8	0.7	0.9	-0.3	-0.6	1.3	-0.1	-0.1	-0.1	-0.2	-0.3	-0.4	0.0	0.1	0.6	0.7	0.5
Age at last live birth	0.2	0.3	1.1	-0.1	0.4	0.4	0.7	-0.2	0.6	-1.0	0.6	0.1	0.4	0.7	0.7	0.6	0.3	0.3	0.5	-0.0	0.7	0.5
Knee pain experienced in last month	0.2	0.3	1.6	-0.5	-0.3	-0.3	-1.2	1.3	-0.4	0.9	-0.3	-0.3	-0.4	-0.3	-0.2	-0.3	-0.4	-0.2	-0.2	0.0	-0.3	-0.7
Mineral and other dietary supplements	0.2	0.2	1.8	1.0	0.2	0.4	1.3	0.1	0.4	0.5	-0.8	0.0	0.2	0.5	0.4	0.3	0.2	0.0	0.3	0.0	-0.2	-0.3
Osteoporosis (self-reported)	0.2	0.2	1.0	-0.3	-0.1	-0.5	-0.9	-0.3	0.3	-0.7	-1.0	0.6	0.0	0.2	0.1	0.2	-0.4	0.3	0.0	-0.1	-0.4	-1.0
Wears glasses or contact lenses	0.2	0.3	1.1	0.0	-0.4	0.6	0.6	-0.7	0.7	0.1	-0.1	1.0	0.6	0.7	0.3	0.5	0.9	0.5	0.4	-0.1	0.2	0.2
Tinnitus: Yes, now most or all of the time	0.2	0.3	1.3	-1.1	-0.0	-0.5	-1.0	-0.4	-0.0	0.1	-0.6	-0.4	-0.3	-0.5	-0.4	-0.3	-0.3	-0.4	-0.6	-0.6	-0.6	-0.1
Illnesses of father: High blood pressure	0.2	0.2	2.0	-0.8	-0.1	-0.0	-0.6	0.2	0.3	-1.4	-0.6	0.3	0.0	-0.1	0.2	0.1	-0.2	-0.2	0.1	-0.2	-0.5	-0.6
Average weekly beer plus cider intake	0.2	0.3	1.3	-1.0	1.1	0.5	-1.2	1.1	-0.1	-0.1	-0.0	0.2	0.4	0.2	0.4	0.4	0.1	0.5	0.4	0.5	0.3	-0.4
Cholesterol lowering medication	0.2	0.2	1.5	0.1	-0.4	0.4	0.7	-0.6	0.1	0.6	-1.2	-0.6	-0.3	-0.2	0.2	-0.1	-0.3	-0.4	-0.1	-0.3	-0.7	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.9	1.0	0.7	-0.2	0.4	0.9	0.4	0.2	0.1	0.4	0.3	0.2	0.6	0.4	0.3	0.3	0.5	0.8	0.3	-0.0
Arm predicted mass (left)	0.2	1.1	3.6	-0.6	1.6	0.6	0.3	0.5	1.4	1.9	0.6	-0.3	1.1	1.0	1.6	1.1	1.5	0.9	1.3	0.2	1.0	-0.1
Depressed Affect (Nagel 2018)	0.1	0.1	0.5	-0.0	0.7	-0.4	-0.7	0.4	0.1	-0.3	0.3	-0.1	0.3	0.2	0.5	0.3	-0.1	0.4	0.3	0.3	0.2	0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.3	2.4	-0.3	-0.4	-0.8	-0.5	-0.3	-0.3	-0.3	-1.6	-0.3	-0.0	-0.4	0.0	-0.1	0.2	-0.3	-0.2	0.0	-0.7	-1.2
Smoking Status	0.1	0.3	1.4	0.3	0.2	0.5	-0.1	0.9	-0.3	-0.3	-1.2	-0.1	-0.2	-0.5	-0.6	-0.2	-0.2	-0.3	0.0	-0.6	-0.9	-1.1
Allergy or Eczema	0.1	0.4	1.4	0.6	-1.1	0.9	0.2	0.3	-0.1	-0.2	-0.0	-0.1	-0.6	-0.3	-0.8	-0.4	-0.4	-0.9	-0.2	-1.2	-1.2	0.2
Respiratory disease	0.1	0.3	0.9	-0.4	0.5	0.2	-0.1	0.3	0.4	0.1	-0.5	-0.5	0.6	0.8	0.7	0.8	0.4	0.6	0.6	-0.1	0.2	-1.0
Relative age of first facial hair	0.1	0.3	1.6	-1.2	0.2	0.9	-0.0	0.1	1.0	0.1	0.4	0.3	0.6	0.5	0.6	0.7	0.3	0.5	0.6	0.1	0.5	0.0
Systolic blood pressure, automated reading	0.1	0.4	3.7	0.1	-0.5	-1.0	-0.2	-0.4	0.1	1.9	-0.2	0.7	-0.4	-0.4	-0.2	-0.3	-0.4	-0.2	-0.3	-0.0	-0.5	-0.7
Impedance of leg (right)	0.1	0.5	2.3	-1.4	-0.7	1.3	0.3	-0.2	-0.1	0.0	0.7	0.7	-0.3	-0.4	-0.8	-0.4	-0.4	-0.2	-0.4	0.5	0.5	1.5
Leg fat-free mass (left)	0.1	0.5	1.6	0.4	1.3	-0.4	0.2	0.4	0.9	1.2	-0.3	-0.8	0.5	0.5	1.2	0.6	0.9	0.3	0.6	-0.6	-0.0	-0.7
Fed-up feelings	0.1	0.3	1.3	-0.3	0.6	-0.1	-1.2	0.9	0.3	-0.0	0.6	0.0	0.3	0.4	0.6	0.2	-0.0	0.6	0.1	0.8	0.7	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.0	-0.7	0.3	0.2	-1.0	0.7	0.5	-0.7	-0.1	0.6	0.2	0.2	0.5	0.3	0.3	0.1	0.3	-0.1	0.1	-0.5
Sitting height	0.1	0.4	1.4	-0.5	-0.3	0.0	0.2	-0.8	-0.6	0.4	0.5	-0.6	-0.7	-0.8	-1.0	-0.7	-0.2	-0.9	-0.8	-1.2	-0.4	0.5
Impedance of leg (left)	0.1	0.4	2.8	-1.0	-0.8	1.1	0.1	0.3	-0.0	-0.1	0.7	0.7	-0.4	-0.4	-0.9	-0.6	-0.4	-0.2	-0.4	0.5	0.4	1.7
Leg predicted mass (left)	0.1	0.5	1.7	0.3	1.3	-0.3	0.2	0.5	1.0	1.2	-0.2	-0.8	0.6	0.5	1.3	0.7	1.0	0.3	0.7	-0.6	0.1	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.9	-0.0	-0.0	-0.3	-0.5	0.3	-0.7	-0.9	1.0	-0.3	0.1	-0.0	-0.2	-0.1	-0.3	0.2	-0.1	-0.0	0.7	-0.1
Hearing difficulty/problems with background noise	0.1	0.2	1.1	0.4	0.7	0.0	-0.2	0.5	1.1	0.4	-0.8	-0.1	0.2	-0.0	0.2	0.1	0.6	-0.0	0.1	-0.7	-0.1	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.8	-0.9	-0.2	-0.1	-1.3	1.0	0.0	-0.7	0.3	0.1	-0.6	-0.5	0.0	-0.4	-0.4	-0.5	-0.3	-0.2	-0.1	0.0
Allergy	0.1	0.3	1.5	0.1	0.4	0.0	0.6	-0.1	0.2	0.3	0.9	0.5	0.4	0.2	0.4	0.2	0.5	0.5	0.3	0.7	1.2	1.1
Trunk fat-free mass	0.1	0.7	2.1	-1.4	1.1	0.5	-0.1	0.1	0.9	1.1	0.9	-0.8	0.7	0.6	1.2	0.8	1.2	0.4	0.9	0.1	1.0	0.1
Father’s age at death	0.1	0.1	0.6	0.7	-0.6	-0.5	0.4	-0.4	0.0	-0.6	0.2	0.4	-0.1	-0.2	-0.1	-0.1	-0.2	-0.1	-0.1	0.2	-0.2	0.7
Trunk predicted mass	0.1	0.7	2.2	-1.5	1.1	0.4	-0.2	0.2	0.9	1.1	0.9	-0.9	0.7	0.6	1.2	0.8	1.2	0.5	0.9	0.2	1.1	0.2
Standing height	0.1	0.6	4.3	-2.1	0.0	-0.2	-0.1	-0.3	-0.0	0.6	0.8	-1.3	-0.7	-0.9	-0.6	-0.8	-0.0	-0.9	-0.8	-1.0	-0.1	1.1
Worry too long after embarrassment	0.1	0.2	1.7	0.6	-0.1	0.1	0.2	-1.3	-0.1	-0.3	0.1	0.9	0.4	0.6	0.1	0.3	0.0	0.3	0.4	-0.0	-0.4	-0.6
Heart disease (mother)	0.1	0.1	0.6	0.2	0.3	-0.6	-0.8	0.7	0.0	0.1	-0.1	-0.3	0.0	0.0	0.1	0.1	0.1	0.1	0.2	-0.3	0.1	-0.1
Arm predicted mass (right)	0.1	0.6	2.0	-1.2	1.0	0.4	-0.2	0.3	1.0	1.4	0.3	-0.8	0.6	0.5	1.1	0.7	1.1	0.4	0.8	-0.1	0.5	-0.3
Comparative height size at age 10	0.1	0.6	4.5	-1.2	-0.1	-0.3	0.4	0.3	-0.5	-0.8	1.3	-1.2	-0.4	-0.1	-0.7	-0.3	0.3	-0.4	-0.4	0.3	0.9	2.1
Whole body fat-free mass	0.1	0.5	1.4	-0.8	1.1	0.0	-0.1	0.4	1.0	1.1	0.4	-0.9	0.6	0.5	1.2	0.7	1.1	0.3	0.8	-0.2	0.6	-0.2
Leg fat-free mass (right)	0.1	0.4	1.4	0.5	1.2	-0.5	0.1	0.7	0.9	0.8	-0.2	-0.7	0.5	0.5	1.2	0.6	0.9	0.2	0.6	-0.5	0.0	-0.6
Whole body water mass	0.1	0.5	1.4	-0.7	1.0	0.1	-0.1	0.3	0.9	1.1	0.4	-0.9	0.6	0.5	1.2	0.7	1.1	0.3	0.8	-0.2	0.5	-0.2
Leg predicted mass (right)	0.1	0.5	1.6	0.5	1.2	-0.5	0.1	0.7	1.0	0.9	-0.2	-0.6	0.5	0.5	1.2	0.6	1.0	0.3	0.7	-0.5	0.0	-0.6
Basal metabolic rate	0.1	0.7	2.3	-0.2	1.3	0.3	0.4	0.5	1.2	1.5	0.2	-0.7	0.8	0.7	1.5	0.9	1.3	0.5	1.0	-0.2	0.6	-0.3
Arm fat-free mass (left)	0.1	0.7	2.8	-0.6	1.3	0.5	0.3	0.3	1.0	1.7	0.4	-0.7	0.7	0.6	1.2	0.8	1.2	0.5	1.0	-0.1	0.6	-0.2
Impedance of whole body	0.1	0.7	1.9	0.6	-1.1	0.2	0.5	0.1	-0.6	-0.7	-0.0	0.4	-1.1	-1.1	-1.4	-1.2	-1.2	-1.0	-1.2	-0.4	-0.7	1.1
Tanning	0.0	0.2	1.9	0.3	0.1	0.2	-0.3	1.4	-0.4	-0.0	-0.4	0.1	0.4	-0.3	0.4	0.2	0.4	0.5	0.5	0.6	0.4	-0.3

Hub : Genes

TBC1D4

Models

Trait associations