Hub : Genes

TBCA

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0710 0.0210 1.5e-05 0.067 0.032 0.045 0.034 0.050 1.5e-08 8.4e-05 3.0e-06 4.5e-05 9.2e-07
2 GTEx Adipose Subcutaneous 0.1290 0.0470 3.5e-03 0.063 NA 0.036 NA 0.067 6.8e-06 NA 5.8e-04 NA 3.7e-06
3 GTEx Artery Aorta 0.1340 0.0460 9.6e-04 0.098 NA 0.088 NA 0.078 4.8e-06 NA 1.5e-05 NA 4.3e-05
4 GTEx Artery Tibial 0.1181 0.0417 8.7e-04 0.120 NA 0.098 NA 0.113 1.3e-09 NA 4.2e-08 NA 3.6e-09
5 GTEx Brain Cerebellum 0.4330 0.1000 3.3e-05 0.093 NA 0.128 NA 0.061 1.1e-03 NA 1.3e-04 NA 7.2e-03
6 GTEx Colon Transverse 0.3100 0.0830 8.7e-04 0.005 NA 0.098 NA 0.050 1.8e-01 NA 2.2e-05 NA 2.1e-03
7 GTEx Esophagus Mucosa 0.2110 0.0460 5.6e-08 0.145 NA 0.119 NA 0.123 6.6e-10 NA 2.3e-08 NA 1.5e-08
8 GTEx Heart Left Ventricle 0.1356 0.0541 7.6e-03 0.100 NA 0.018 NA 0.068 5.4e-06 NA 3.5e-02 NA 1.8e-04
9 GTEx Muscle Skeletal 0.1567 0.0410 2.4e-06 0.052 NA 0.081 NA 0.084 6.9e-06 NA 2.3e-08 NA 1.4e-08
10 GTEx Testis 0.1790 0.0660 8.6e-03 0.127 NA 0.087 NA 0.119 3.0e-06 NA 1.1e-04 NA 6.2e-06
11 YFS Blood 0.2420 0.0312 0.0e+00 0.246 0.242 0.258 0.256 0.250 1.3e-79 2.9e-78 7.2e-84 2.9e-83 4.2e-81
12 TCGA Glioblastoma Multiforme 0.3240 0.1340 6.6e-03 0.007 -0.009 0.048 NA 0.049 1.9e-01 8.4e-01 1.4e-02 NA 1.3e-02
13 TCGA Kidney Renal Clear Cell Carcinoma 0.0363 0.0225 4.1e-03 0.013 0.021 0.010 NA 0.007 1.1e-02 1.8e-03 2.6e-02 NA 4.6e-02
14 TCGA Testicular Germ Cell Tumors 0.1730 0.0960 9.7e-03 -0.008 0.020 0.045 NA 0.002 8.2e-01 6.6e-02 1.0e-02 NA 2.7e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.4 0.6 1.7 -0.9 0.9 -0.1 0.4 0.8 0.5 0.3 0.4 -0.8 1.3 1.0 0.5 -1.2 0.9
Bipolar Disorder or Schizophrenia 0.6 1.5 4.4 -1.4 1.3 -0.3 0.8 1.7 1.8 -0.0 -0.2 -0.7 2.1 1.7 0.8 -1.5 0.5
Depressed Affect (Nagel 2018) 0.5 1.0 2.9 1.1 0.6 0.6 0.7 0.8 1.0 1.0 -0.8 0.2 0.3 -0.9 -1.6 1.3 1.7
Depression (Nagel 2018) 0.4 0.6 2.9 0.4 0.5 0.0 0.6 0.8 1.5 0.3 0.8 -0.1 0.8 -0.4 -0.9 0.6 1.7
Intelligence (Savage-Jansen 2018) 0.9 2.8 6.3 -1.8 -1.8 -2.2 -1.6 -1.1 1.1 -2.5 -2.1 -2.0 -1.1 1.5 1.0 -0.6 -2.0
Neuroticism (Nagel 2018) 1.3 3.0 6.0 2.1 1.5 1.6 1.7 2.3 1.0 2.3 0.2 1.2 1.2 -1.9 -1.2 2.0 2.5
Schizophrenia (2018) 0.5 1.0 3.7 -1.1 1.0 -0.3 0.7 1.6 1.9 -0.3 -0.6 -0.2 1.6 1.3 0.6 -0.7 -0.1
Schizophrenia vs Biploar Disorder 0.6 0.8 2.5 -0.8 -0.8 -1.0 -0.7 -0.3 0.1 -1.1 -1.0 -0.7 -0.5 1.0 1.6 -0.8 -1.3
Worry (Nagel 2018) 1.4 3.0 5.9 2.1 1.7 1.8 1.9 2.2 0.2 2.2 0.4 1.5 1.4 -2.2 0.1 1.7 2.4
Alzheimer’s Disease (in mother) 0.2 0.3 1.7 0.2 -0.2 -0.4 -0.2 1.3 -0.5 0.8 0.6 -0.6 -0.5 0.1 -0.1 -0.2 -0.0
Alzheimer’s Disease (in father) 3.0 3.2 9.4 -0.5 -2.7 -2.3 -2.4 -0.2 -0.5 -1.8 -2.8 -2.0 -3.1 0.4 0.3 -0.4 -1.1
Alzheimer’s Disease (including proxy) 0.3 0.4 1.6 0.6 -1.2 -0.7 -0.7 0.7 -0.6 0.5 0.0 -0.4 -1.2 -0.3 0.3 0.2 -0.3
Crohns Disease (2017) 0.2 0.5 2.0 0.5 -0.5 -0.4 -0.3 -0.1 -0.3 -0.1 -1.4 0.1 -0.9 -0.9 1.1 0.8 0.7
Irritable Bowel Disease (IBD) 0.1 0.3 1.6 -0.2 0.4 0.0 0.1 -0.1 0.8 0.1 -1.2 0.1 0.4 0.3 0.8 -0.3 0.4
Ulcerative Colitis (UC) 0.5 0.9 3.0 -1.1 1.0 0.2 0.5 0.1 1.6 -0.1 -0.2 -0.0 1.5 1.7 0.7 -1.1 -0.1
Major Depression (MDD) 0.7 0.9 2.6 0.6 -1.2 -0.6 -0.9 -0.8 0.2 -0.7 -1.1 -0.3 -1.4 -0.7 -1.1 1.6 -0.8
Reaction Time 1.4 2.7 6.4 1.3 1.9 2.3 1.9 -1.7 0.3 1.9 2.5 1.8 2.0 -1.2 -0.2 1.3 0.8
Verbal and Numeric Reasoning (VNR) 0.1 0.2 1.2 -0.0 0.4 0.2 0.3 -0.3 0.5 -0.1 0.4 0.5 0.6 -0.0 -0.0 0.7 -1.1
Breast Cancer 0.2 0.6 2.5 -0.6 -0.1 -0.7 0.1 -0.8 1.3 -1.6 0.2 -1.0 0.4 0.4 0.6 -0.8 -0.2
Ovarian Cancer 1.0 1.3 5.2 1.3 0.7 1.4 0.9 0.3 -2.3 1.0 0.9 0.9 0.4 -1.3 -0.1 1.8 -0.1
Prostate Cancer 1.7 2.4 5.3 2.2 1.1 1.4 1.3 1.7 0.2 2.2 1.1 2.2 0.5 -2.3 -0.9 2.0 0.5
Age at First Birth 0.8 1.1 2.0 1.2 1.3 1.3 1.4 0.5 -0.6 1.1 1.3 1.0 1.4 -1.0 0.8 0.6 -0.1
Bipolar Disorder (2011) 0.3 0.3 1.2 -0.2 0.7 0.3 0.8 0.0 0.8 0.2 -1.0 -0.3 1.1 0.3 0.2 0.0 0.4
Body Mass Index (BMI) (2010) 1.9 2.6 6.7 -1.0 -2.5 -2.1 -2.4 -1.3 -1.1 -1.7 -1.0 -1.4 -2.6 0.6 0.9 -0.7 -1.4
Coronary Artery Disease (CAD) 0.1 0.2 0.6 -0.4 -0.3 -0.5 -0.3 0.3 -0.3 -0.2 -0.6 -0.4 -0.0 0.4 0.8 -0.6 0.3
Crohns Disease (2012) 0.3 0.6 4.8 0.3 -0.5 -0.1 -0.2 -0.1 -0.6 -0.2 -2.2 -0.3 -0.6 -0.8 0.8 0.7 0.1
Mean Putamen Volume 0.5 0.6 2.0 -0.2 1.1 1.1 0.8 -1.4 1.1 0.4 0.6 0.3 1.1 0.3 0.2 -0.5 0.2
Fasting Glucose 0.8 0.9 3.0 -0.1 -1.2 -1.7 -1.3 0.2 -0.8 -1.2 -1.0 -0.6 -1.5 -0.7 0.2 0.4 0.1
HbA1C 0.2 0.2 1.3 0.5 -0.3 -0.0 0.1 -0.2 -1.1 0.1 -0.4 0.0 -0.4 -0.3 0.8 0.1 0.2
HDL Cholesterol 0.4 0.6 2.0 -0.0 -1.1 -0.7 -1.1 -0.1 -1.1 -0.2 0.2 -0.7 -1.4 -0.2 -1.3 0.2 0.6
LDL Cholesterol 0.3 0.5 2.2 0.6 0.6 0.6 0.4 0.9 -1.5 1.1 0.2 0.9 0.1 -0.1 0.7 0.3 -0.8
Lupus 0.5 0.8 4.4 -0.6 0.3 -0.6 0.5 2.1 0.9 -0.8 -1.2 -0.7 0.6 0.4 0.1 -0.8 1.1
Neuroticism (2016) 2.0 2.9 5.5 2.3 2.0 1.7 2.1 1.7 1.0 2.0 0.9 2.1 1.8 -1.9 0.3 1.7 0.8
Primary Biliary Cirrhosis 0.3 0.5 1.9 -0.1 0.8 0.6 0.6 1.4 0.8 0.8 0.6 0.7 1.1 0.3 -0.3 0.2 -0.0
Rheumatoid Arthritis 1.1 1.6 6.3 -1.3 -1.3 -1.6 -1.1 0.1 0.5 -1.4 -2.5 -1.3 -1.1 1.2 -0.2 -1.2 0.0
Schizophrenia (2014) 0.7 1.4 5.3 -1.7 0.4 -1.1 -0.1 0.6 2.3 -0.7 -0.2 -0.9 1.4 2.0 0.8 -1.5 0.0
Triglycerides 0.7 1.2 4.4 1.5 1.1 1.2 1.0 0.7 -0.3 1.4 -0.4 2.1 0.7 -1.0 0.3 1.5 -0.4
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.9 -0.7 -1.0 -1.2 -0.8 -1.1 0.4 -1.4 0.0 -0.5 -0.6 1.2 0.2 -0.5 -0.7
Ulcerative Colitis 0.2 0.3 1.0 -0.4 0.6 0.3 0.4 0.1 -0.1 -0.4 -0.4 -0.0 1.0 0.8 1.0 -0.6 -0.1
Blood Eosinophil Count 0.2 1.5 3.9 -1.6 -1.1 -1.2 -1.6 -1.7 -0.2 -0.4 1.2 -1.0 -1.3 2.0 0.1 -1.2 -0.7
Blood Platelet Count 1.4 16.3 52.7 6.7 -1.6 1.1 0.1 4.1 -4.7 3.3 -1.3 3.0 -3.8 -6.4 -2.0 7.3 2.6
Blood Red Count 0.3 2.6 10.8 -2.2 -0.0 -1.6 -0.4 3.3 0.2 -1.4 -1.2 -1.1 0.3 2.8 0.7 -2.0 -0.4
Blood White Count 0.2 1.3 12.4 0.1 0.7 -0.4 0.5 3.5 0.4 1.0 1.1 0.9 0.6 -0.3 -0.5 0.3 1.1
Heel T-Score 0.4 2.8 11.4 1.1 2.0 2.0 1.9 0.8 0.4 1.5 1.5 1.9 1.9 -0.6 -3.4 1.8 0.4
BMI 0.8 4.9 8.9 -2.7 -2.1 -3.0 -2.2 -0.1 -0.6 -2.8 -1.4 -2.5 -1.7 2.4 1.4 -2.6 -3.0
Height 0.3 4.9 15.3 -1.8 -1.9 -2.6 -1.9 0.7 3.9 -2.1 -0.9 -1.9 -1.4 0.6 3.3 -1.3 -3.5
Waist Hip Ratio (WHR) 0.3 1.2 8.1 -1.5 0.3 -1.4 -0.1 2.9 0.4 -0.0 -0.2 -0.4 0.5 1.6 -0.2 -1.3 0.0
Systolic Blood Pressure 0.2 1.0 4.5 -0.9 -0.1 -1.0 -0.1 -0.7 1.4 -1.0 -2.1 -0.5 0.4 0.9 1.2 -1.2 0.7
Smoking Status 0.2 0.6 4.2 0.3 0.2 0.8 0.1 -0.6 -0.6 0.5 -2.1 0.5 -0.0 -0.3 -0.6 0.0 1.3
Allergy or Eczema 0.2 0.6 2.7 0.0 -1.4 -0.7 -1.2 -0.5 -0.5 -0.7 0.0 -0.2 -1.6 -0.2 0.4 0.1 -0.4
Cardiovascular Disease 0.3 0.9 3.4 -1.1 -0.2 -1.6 -0.3 1.2 1.9 -0.8 -0.2 -0.7 0.3 0.7 -0.8 -0.7 0.8
Hypothyroidism (self reported) 0.7 1.6 4.8 1.7 -0.2 0.9 0.3 -2.2 -2.2 0.3 -0.1 0.9 -0.5 -1.6 0.3 2.1 0.3
Respiratory disease 0.1 0.3 1.8 -0.6 -0.3 0.1 -0.4 0.9 -0.2 0.1 -1.3 -0.1 -0.5 0.5 0.5 -0.3 -0.5
Type 2 Diabetes (T2D) (2018) 0.4 0.7 2.4 -0.3 -0.4 -1.3 -0.3 1.5 -0.9 -1.1 -0.0 -0.5 -0.4 0.2 1.1 -0.2 -1.2
Lung FEV1/FVC ratio 0.3 1.3 4.4 -1.2 -0.0 -0.8 -0.4 -2.1 -0.2 -1.4 2.1 -1.0 -0.0 1.6 -0.1 -1.5 -0.4
Lung FVC 1.0 5.0 17.1 3.2 0.3 1.7 1.1 1.3 0.3 2.1 -4.1 1.5 -0.4 -3.4 -2.2 3.5 1.3
Neuroticism 1.3 3.1 7.3 2.0 1.8 1.8 1.7 2.4 -0.5 2.2 0.8 1.4 1.2 -1.8 -1.0 1.7 2.7
Chronotype (morning person) 2.8 6.5 14.7 3.1 2.6 3.8 3.0 -1.0 -2.2 2.8 2.3 2.4 2.3 -3.1 -0.3 2.1 2.3
Hair Pigment 0.0 1.3 2.7 1.3 1.2 0.9 1.2 0.7 -1.6 0.7 1.2 1.5 0.8 -1.2 0.1 0.8 1.6
Tanning 0.1 1.5 12.5 -0.1 0.0 0.8 -0.0 -3.5 1.3 0.3 -0.7 -0.4 0.2 -0.1 1.4 -0.4 -1.6
Hand grip strength (left) 0.4 1.1 4.0 1.4 -0.5 0.3 -0.0 0.5 -2.0 -0.0 -1.0 0.2 -0.9 -1.5 -0.5 2.0 -0.1
Number of treatments/medications taken 3.7 6.7 11.4 -3.0 -3.3 -3.4 -3.2 -1.6 0.9 -3.3 -0.4 -3.1 -2.9 2.8 1.6 -2.3 -1.8
Average weekly spirits intake 0.7 0.9 2.7 0.8 -1.3 -0.1 -0.8 -1.4 0.0 -0.3 -1.6 0.2 -1.4 -0.5 -1.1 1.2 0.2
Sensitivity / hurt feelings 0.8 1.4 2.9 0.9 1.4 1.5 1.2 0.0 1.5 1.7 1.4 0.7 1.4 -0.6 -0.8 1.1 0.9
Frequency of depressed mood in last 2 weeks 0.4 0.6 3.5 0.7 0.7 0.5 0.7 -0.7 0.3 0.6 0.8 0.3 0.8 -0.5 -0.6 0.6 1.9
Hearing difficulty/problems: Yes 0.6 0.8 6.7 -0.7 -0.1 -1.0 -0.3 2.6 1.0 -0.0 0.2 -0.4 -0.0 0.6 -0.2 -1.3 -0.6
Relative age of first facial hair 0.1 0.2 0.9 -0.2 -0.2 -0.4 -0.0 0.4 0.2 -0.7 -0.9 -0.3 0.1 0.5 0.0 -0.3 0.3
Other serious medical condition/disability diagnosed by doctor 2.4 3.2 7.2 -1.7 -2.3 -2.5 -2.3 0.1 1.4 -1.9 -0.7 -1.4 -2.2 1.4 1.0 -1.3 -2.7
Ever used hormone-replacement therapy (HRT) 1.8 2.2 8.0 1.2 1.9 1.8 1.9 0.5 0.1 1.3 2.8 1.4 1.9 -1.4 1.0 0.5 1.0
Ever had hysterectomy (womb removed) 0.3 0.4 2.7 -0.1 0.6 0.5 0.4 0.2 0.3 0.5 1.6 -0.2 0.7 -0.0 0.4 -0.6 0.6
Systolic blood pressure, automated reading 0.1 0.2 0.5 0.3 0.3 0.1 0.4 0.3 0.2 -0.1 -0.6 0.7 0.4 -0.7 0.2 -0.2 -0.5
Eye problems/disorders: Diabetes related eye disease 1.4 1.5 4.5 -0.7 -1.8 -1.2 -1.6 -1.5 -0.1 -1.0 -2.1 -1.3 -1.9 0.8 0.2 -0.3 -0.1
Angina 0.6 0.8 2.2 0.8 1.2 1.5 1.2 0.2 0.1 1.1 0.9 1.0 1.1 -0.5 0.6 0.7 0.4
Medication for hormone replacement therapy 0.4 0.5 2.3 -0.5 -0.0 0.3 0.0 -1.3 0.3 -0.7 0.7 -0.4 0.0 0.8 1.5 -0.8 -0.1
Vitamin and mineral supplements 1.2 1.6 3.3 1.6 1.5 1.4 1.6 1.0 -0.1 1.4 0.8 1.6 1.4 -1.8 0.4 0.7 0.5
Supplements: Zinc 1.1 1.2 3.7 0.1 -1.7 -1.2 -1.3 -0.9 -0.1 -1.0 -1.6 -0.7 -1.9 0.2 -0.7 0.7 -1.1
Medication: Co-codamol 0.8 0.9 3.0 -1.1 -0.5 -1.4 -0.6 -0.4 1.7 -1.0 -0.3 -1.1 -0.1 1.4 0.4 -0.9 -0.8
Medication: Metformin 0.4 0.5 2.7 -0.1 0.9 0.2 0.8 1.6 -0.6 0.1 0.7 0.5 0.8 0.1 1.0 -0.1 -0.6
Diabetes (father) 0.7 0.9 3.9 -0.6 0.5 0.0 0.2 1.6 2.0 0.4 1.5 0.3 0.6 1.0 -1.0 -0.1 -0.4
Diabetes (mother) 0.4 0.5 3.4 -0.5 -0.5 -1.0 -0.4 0.5 1.8 -0.9 -0.0 -0.3 -0.1 0.5 -0.5 -0.3 -0.1
Severe depression (siblings) 0.5 0.5 2.7 0.3 -0.5 -0.3 -0.1 0.8 -1.7 -0.2 0.6 -0.3 -0.5 -0.7 -1.4 0.6 -0.2
Pack years adult smoking proportion 0.6 0.8 4.4 0.5 -1.2 -0.7 -0.8 -0.3 -0.9 -0.6 -2.1 -0.6 -1.4 -0.5 0.0 0.9 -0.3
Impedance of leg (right) 0.4 2.1 6.2 0.9 1.3 1.8 1.2 0.4 2.5 1.8 0.9 1.4 1.5 -0.3 -1.5 1.6 1.8
Leg fat-free mass (left) 1.3 6.7 14.8 -2.7 -2.5 -3.9 -2.4 0.2 -0.5 -3.6 -2.9 -3.2 -2.0 1.8 1.7 -2.8 -3.2
Trunk fat percentage 0.4 1.6 4.8 -1.2 -1.3 -2.2 -1.1 1.7 0.1 -1.4 -1.0 -1.2 -1.1 0.9 -0.6 -1.5 -1.1
Hand grip strength (right) 0.5 1.4 5.2 0.4 -1.5 -0.6 -1.1 -1.3 -0.8 -1.0 -2.3 -1.0 -1.6 -0.8 -1.4 0.9 -0.4
Townsend deprivation index at recruitment 1.0 1.5 4.5 1.7 1.0 1.1 1.2 0.7 -1.4 1.3 0.1 1.4 0.8 -1.2 -0.2 2.1 1.1
Current tobacco smoking 0.6 1.0 3.6 -0.9 -0.4 -0.7 -0.7 -1.0 -0.4 -1.0 -1.9 -1.2 -0.1 1.1 -1.5 -0.7 0.9
Average weekly fortified wine intake 0.5 0.6 2.6 0.1 0.9 0.9 0.7 1.0 -0.2 1.0 1.6 -0.2 0.6 0.2 -0.0 0.1 0.8
Maternal smoking around birth 0.7 1.0 6.2 0.1 -1.0 -0.8 -1.0 1.4 -0.2 0.0 -2.5 -1.0 -1.2 -0.3 -1.1 0.1 0.0
Fed-up feelings 0.5 0.9 2.8 0.8 0.8 0.5 0.8 0.6 0.3 1.0 -1.2 0.4 0.7 -0.1 -1.6 1.2 1.7
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.3 1.1 0.3 0.7 0.0 0.9 0.9 0.6 0.2 -0.3 0.0 1.0 -0.2 -0.0 0.4 1.0
Relative age voice broke 0.5 0.8 3.3 0.7 0.5 0.4 0.8 0.8 0.4 0.3 1.8 0.9 0.6 -1.1 1.5 0.4 0.3
Taking other prescription medications 1.5 2.3 5.1 -1.3 -2.2 -2.3 -1.9 -1.3 0.4 -2.2 -0.2 -1.4 -1.9 1.2 0.7 -0.6 -1.1
Age when periods started (menarche) 0.4 1.0 5.0 -1.0 1.2 0.7 0.6 -0.4 -0.1 0.3 2.2 0.1 1.6 0.8 0.6 -1.3 0.1
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.0 1.2 0.2 0.9 0.5 0.4 -1.1 0.5 0.2 0.5 0.1 -1.4 1.2 0.6 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.8 8.2 0.8 -1.2 0.4 -0.8 -0.8 -2.6 0.2 0.1 0.3 -1.9 -0.7 -2.9 1.5 0.3
Tinnitus: Yes, but not now, but have in the past 2.1 2.2 5.5 1.2 1.9 1.0 2.0 1.3 0.1 0.9 2.4 1.4 2.0 -1.3 -0.8 1.4 1.8
Qualifications: CSEs or equivalent 1.0 1.4 6.7 -0.4 -1.2 -0.5 -1.2 -1.0 -1.6 -0.2 -2.6 -0.9 -1.8 0.6 1.0 -0.2 -0.1
Serious illness, injury or assault to yourself 0.4 0.5 1.4 -0.3 -1.0 -0.8 -0.9 0.7 -0.2 -0.5 -0.8 -0.7 -1.2 0.4 1.0 -0.1 0.2
High blood pressure 0.5 1.5 3.8 -1.9 -0.5 -2.0 -0.9 1.1 1.1 -1.3 -0.3 -0.9 -0.2 1.6 0.8 -1.8 -1.4
Hayfever, allergic rhinitis or eczema 0.5 1.0 3.9 -0.6 -1.6 -1.0 -1.6 -0.3 -0.8 -0.7 0.2 -0.6 -2.0 0.7 0.2 -0.3 -1.2
Multivitamins +/- minerals 0.4 0.6 1.8 -1.1 -0.7 -0.5 -0.8 -1.0 -0.1 -0.8 -0.1 -0.8 -0.6 1.4 -0.7 -0.4 -0.4
Stomach or abdominal pain in last month 0.3 0.4 2.1 -0.2 -0.5 -0.4 -0.4 1.5 -1.1 -0.1 -0.3 -0.3 -0.7 0.2 -0.3 -0.3 -0.0
Supplements: Glucosamine 1.9 2.5 5.1 1.8 1.1 1.8 1.2 0.7 -1.0 2.2 1.6 1.7 0.6 -1.8 -2.2 2.0 1.3
Diverticular disease/diverticulitis (self-reported) 1.8 2.1 6.5 -1.1 -1.8 -0.9 -1.7 -2.5 0.8 -1.4 -2.2 -1.6 -1.3 1.0 0.1 -1.1 -0.8
Medication: Atenolol 1.0 1.2 3.1 -1.1 -1.1 -1.1 -1.3 -0.9 0.7 -0.9 -0.2 -1.1 -1.2 0.9 1.8 -1.2 -1.2
Medication: Levothyroxine sodium 0.6 1.1 3.5 0.1 -1.1 -0.5 -1.1 -1.3 -1.9 -0.2 0.8 0.1 -1.7 0.3 -0.1 1.0 -1.6
Sitting height 0.4 3.0 19.4 0.3 -1.5 -1.5 -1.0 2.0 -0.1 -1.3 -4.4 -0.9 -1.9 -1.1 1.6 0.6 -1.7
Chronic bronchitis/emphysema (father) 0.5 0.5 1.3 -0.9 -0.8 -0.6 -1.2 -0.9 0.9 -0.3 -0.1 -0.4 -0.8 1.1 -0.6 -0.2 -0.5
High blood pressure (mother) 1.3 1.8 5.4 -1.6 -1.3 -1.9 -1.2 -1.4 0.3 -2.3 0.3 -1.5 -0.7 1.0 0.1 -1.2 -1.6
Body mass index (BMI) 0.6 2.3 5.2 -1.6 -1.6 -2.3 -1.5 0.7 -1.2 -1.8 -1.7 -1.8 -1.5 1.4 0.1 -1.9 -1.2
Impedance of leg (left) 0.5 2.2 5.4 0.7 1.6 2.0 1.2 0.2 2.3 2.0 1.3 1.6 1.6 -0.1 -1.3 1.3 1.7
Leg predicted mass (left) 1.3 6.8 14.9 -2.6 -2.6 -3.9 -2.4 0.2 -0.5 -3.6 -2.8 -3.2 -2.1 1.8 1.7 -2.8 -3.2
Trunk fat mass 0.7 3.0 8.2 -1.8 -1.8 -2.9 -1.7 1.6 0.2 -2.0 -1.6 -1.9 -1.6 1.3 0.0 -2.0 -1.8
Waist circumference 0.9 3.1 8.4 -2.0 -1.6 -2.9 -1.7 1.7 -0.7 -1.8 -1.2 -2.0 -1.6 1.6 0.3 -2.2 -2.0
Number of incorrect matches in round 2.0 3.3 6.8 1.5 2.2 1.9 2.2 0.5 1.4 1.5 2.6 2.3 2.3 -1.3 -0.8 1.7 1.7
Past tobacco smoking 0.1 0.2 0.9 0.2 0.3 0.2 0.4 0.2 -0.4 0.2 0.8 0.2 0.6 -0.3 -0.9 0.7 0.1
Alcohol usually taken with meals 0.7 1.2 6.5 0.5 1.2 1.2 1.1 0.1 0.1 0.3 2.6 0.2 1.7 -0.6 1.4 -0.1 0.6
Nervous feelings 0.3 0.6 1.6 0.9 0.8 0.8 0.7 1.2 -0.1 1.2 -0.1 0.5 0.5 -1.0 0.7 0.5 0.8
Frequency of tenseness / restlessness in last 2 weeks 2.0 3.2 7.2 1.6 2.3 2.7 2.4 0.3 0.7 2.1 1.0 1.6 2.5 -1.1 0.1 1.3 2.4
Hearing difficulty/problems with background noise 0.3 0.5 2.0 -0.2 0.8 0.1 0.6 1.4 0.5 0.6 -0.3 0.5 1.0 0.2 -0.9 -0.3 1.0
Hair/balding pattern: Pattern 2 0.3 0.4 1.8 -0.4 0.3 0.1 0.1 1.4 -0.1 0.1 -0.5 -0.9 0.2 1.0 0.7 -0.5 0.6
Had menopause 0.3 0.4 1.0 0.3 0.1 0.5 -0.0 0.8 -1.0 0.7 0.5 0.6 -0.2 -0.8 0.5 0.4 -1.0
Had other major operations 1.0 1.3 2.6 -0.9 -1.6 -1.4 -1.4 -0.8 0.7 -1.4 -0.1 -1.1 -1.6 0.9 0.5 -0.2 -1.5
Forced vital capacity (FVC) 0.5 2.1 17.8 1.1 -1.2 0.0 -0.5 0.2 -0.2 -0.2 -4.2 -0.5 -1.7 -1.8 -0.0 1.5 -0.3
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.2 5.6 0.8 -0.8 0.4 -0.4 -0.5 -1.9 -0.1 0.5 0.3 -1.2 -0.6 -2.4 1.8 0.3
Ever unenthusiastic/disinterested for a whole week 0.3 0.3 2.6 -0.6 -0.0 -0.5 -0.3 -0.3 1.6 -0.6 0.5 0.1 0.4 0.7 -0.3 -0.1 0.0
Qualifications: None of the above 0.9 1.9 3.5 1.8 1.5 1.3 1.6 0.6 -0.8 1.5 1.2 1.7 1.1 -1.9 -0.6 1.6 1.3
Financial difficulties in last 2 years 0.6 0.8 4.0 -0.7 1.0 -0.1 0.6 2.0 1.1 0.6 -0.9 -0.3 0.9 1.3 -1.0 -0.4 0.3
Mouth/teeth dental problems 1.6 2.4 8.4 -1.8 -1.4 -1.4 -1.7 -1.0 -0.2 -1.7 -2.9 -1.7 -1.4 1.7 1.0 -1.7 -0.2
Heart attack 1.5 2.0 5.3 -1.9 -1.1 -1.4 -1.2 -1.1 1.0 -1.6 -2.3 -1.8 -0.4 1.9 0.7 -1.4 -0.2
Allergy 0.1 0.3 1.6 0.2 0.6 0.1 0.7 -0.1 1.3 -0.0 0.4 0.0 1.1 -0.4 -0.1 -0.0 0.8
Pain all over the body in last month 0.7 0.8 5.0 -1.5 -0.0 -0.8 -0.5 -0.2 0.2 -0.2 -0.4 -1.0 0.2 2.2 0.1 -1.3 0.4
Diabetes (self-reported) 0.5 0.8 4.7 -0.3 0.4 -0.5 0.5 1.5 -0.2 -0.8 -0.6 0.0 0.3 0.5 2.2 -0.5 -1.3
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 2.8 1.5 -0.1 0.6 0.0 0.5 -1.3 1.2 1.5 1.0 -0.5 -1.7 -0.4 1.4 1.0
Medication: Ramipril 2.8 3.5 9.9 -2.5 -1.2 -2.2 -1.7 -0.3 3.1 -2.0 -2.0 -2.2 -0.8 2.2 0.3 -2.3 -0.6
Medication: Simvastatin 0.5 0.7 4.4 0.9 0.7 0.5 0.7 -0.1 0.7 1.0 0.2 0.7 0.5 -0.9 0.1 0.1 2.1
Fluid intelligence score 0.2 0.4 1.4 0.2 0.6 -0.0 0.8 1.1 1.2 -0.5 0.1 0.3 1.0 -0.2 0.1 0.9 -0.6
Illnesses of siblings 1.0 1.5 2.9 1.6 1.0 1.6 1.2 0.5 -1.5 1.5 -0.0 1.5 0.5 -1.7 -0.3 1.3 0.9
Neuroticism score 0.8 1.6 3.4 1.5 1.3 1.2 1.3 1.4 -0.3 1.6 0.2 1.0 1.0 -1.2 -1.2 1.5 1.8
Weight 1.2 5.8 12.7 -2.6 -2.5 -3.6 -2.5 0.6 -0.1 -3.0 -2.4 -3.0 -2.2 1.9 1.5 -2.6 -2.7
Impedance of arm (right) 0.4 2.1 5.1 1.3 1.2 1.2 1.2 1.7 1.8 1.6 2.3 1.7 1.1 -1.2 -0.7 1.3 1.3
Arm fat percentage (right) 0.4 1.6 4.4 -1.2 -1.4 -2.1 -1.3 1.4 -0.3 -1.2 -0.8 -1.4 -1.3 1.1 -0.7 -1.6 -0.8
Trunk fat-free mass 1.3 7.4 11.9 -3.0 -2.5 -3.4 -2.7 -0.7 0.6 -3.3 -2.9 -3.4 -2.2 2.2 2.8 -2.9 -3.4
Hip circumference 0.8 3.3 6.8 -1.4 -2.3 -2.6 -2.1 0.5 -1.3 -2.1 -2.0 -2.0 -2.4 0.9 1.1 -1.6 -1.9
Time employed in main current job 0.7 0.8 4.7 0.1 0.9 0.0 0.9 1.0 1.1 -0.1 -2.2 0.3 1.1 0.1 0.7 -0.5 0.7
Alcohol intake versus 10 years previously 0.8 1.3 3.9 -1.9 -0.1 -1.1 -0.1 0.2 1.3 -1.6 -0.1 -1.4 0.6 2.0 -0.2 -1.4 -0.7
Father’s age at death 0.6 0.8 3.8 0.2 -1.0 -0.3 -1.0 0.0 -0.3 -0.0 1.0 -0.3 -1.4 -0.2 1.2 0.2 -1.9
Worrier / anxious feelings 1.7 3.1 9.5 1.6 1.8 2.4 1.6 1.2 -0.9 3.1 2.3 1.7 1.0 -1.1 -1.3 1.9 1.2
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 0.5 -0.5 0.3 -0.4 0.1 0.6 0.6 -0.1 -0.1 -0.4 0.6 0.6 -0.7 -0.1 0.1
Falls in the last year 0.9 1.2 3.5 1.1 -0.2 0.8 -0.3 0.3 -1.7 1.7 0.3 1.0 -1.2 -0.7 -1.9 1.5 -0.6
Hair/balding pattern: Pattern 3 0.4 0.6 5.0 0.3 0.2 0.1 0.4 -1.2 0.2 0.0 -0.3 0.5 0.0 -0.6 -2.2 0.9 -0.4
Number of live births 5.6 8.0 18.1 3.5 2.6 3.8 2.6 0.6 -1.1 4.3 3.1 3.8 1.7 -3.6 -1.1 3.0 1.4
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 12.1 1.1 -1.0 -0.2 -0.4 -0.0 -0.5 -0.5 -3.5 -0.4 -1.5 -1.5 -0.6 1.6 -0.4
Pulse rate 0.6 1.0 3.2 -0.4 -1.1 -1.2 -0.9 0.9 -1.1 -1.2 -1.8 -0.9 -1.3 -0.2 -0.6 -0.2 0.8
Happiness 0.4 0.4 2.9 0.3 -0.2 -0.2 -0.2 -0.0 0.6 0.3 1.4 0.1 -0.1 0.0 -1.7 0.6 0.3
Noisy workplace 0.2 0.3 0.8 -0.4 0.6 0.3 0.3 0.2 0.9 -0.0 -0.3 -0.0 0.8 0.6 0.6 -0.6 0.5
Qualifications: A levels/AS levels or equivalent 0.2 0.4 1.5 -0.3 -0.3 -0.4 -0.1 1.0 1.2 -0.5 0.5 -0.2 0.0 0.1 -0.6 -0.4 -1.2
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.0 5.4 -0.8 0.9 -0.0 0.6 1.1 0.5 0.2 2.3 -0.3 1.2 0.9 1.2 -0.9 -0.8
Mouth/teeth dental problems: Dentures 1.7 2.8 6.0 2.3 1.7 1.6 1.9 0.6 0.5 2.1 1.4 2.2 1.4 -2.4 -0.7 2.3 0.3
Asthma 0.2 0.4 1.1 0.1 0.5 0.9 0.5 0.7 -1.1 1.0 -1.1 0.9 0.2 0.1 -0.0 0.4 0.1
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.6 0.7 0.3 0.9 0.4 -1.1 -0.4 0.5 1.3 0.9 0.4 -0.0 -0.5 0.7 -0.2
Medication: Cholesterol lowering 0.5 0.7 2.5 -0.2 1.1 0.5 0.9 0.3 1.6 0.2 0.4 0.1 1.1 0.2 1.2 -0.6 1.3
Depression (self-reported) 1.2 1.5 4.0 1.2 -1.4 -0.6 -0.8 -0.3 -0.9 -0.3 -0.5 -0.0 -1.8 -1.4 -1.9 2.0 1.4
Medication: Lansoprazole 0.8 0.9 2.2 0.8 1.2 0.7 1.5 1.3 -0.9 0.4 -1.0 0.1 1.4 -0.9 1.1 0.2 0.7
Prospective memory result 2.2 2.8 6.6 1.7 1.9 2.6 1.8 -0.6 -0.6 2.2 1.1 2.2 1.9 -1.6 0.7 1.5 1.4
Lung cancer (father) 0.3 0.4 1.6 0.9 -0.4 0.1 -0.2 0.2 -0.8 0.4 -0.6 0.7 -0.7 -0.6 -0.3 1.3 0.3
Illnesses of mother 2.1 2.7 5.7 1.9 2.0 2.4 2.0 0.6 -0.8 1.9 -0.7 2.3 1.8 -1.3 -0.6 1.8 0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.4 10.0 1.1 -1.1 -0.4 -0.3 0.1 -0.3 -0.6 -3.2 -0.6 -1.4 -1.6 -0.5 1.4 -0.2
Pulse wave Arterial Stiffness index 1.3 1.5 3.7 -1.7 -1.2 -1.4 -1.4 0.6 0.2 -1.1 -0.8 -1.8 -1.1 1.9 -0.2 -1.7 0.0
Impedance of arm (left) 0.3 1.5 3.9 1.3 1.0 1.0 1.1 1.2 1.6 1.2 2.0 1.5 1.0 -1.2 -0.2 1.1 1.3
Arm fat mass (right) 0.7 3.0 7.2 -1.7 -1.9 -2.7 -1.9 1.2 -0.7 -1.9 -1.8 -2.0 -1.8 1.4 0.2 -2.1 -1.8
Trunk predicted mass 1.2 7.1 11.4 -2.9 -2.5 -3.3 -2.6 -0.7 0.5 -3.2 -2.9 -3.4 -2.2 2.1 2.7 -2.8 -3.4
Standing height 0.5 5.1 12.0 -2.2 -2.0 -2.8 -2.1 0.2 2.4 -2.5 -1.6 -2.3 -1.7 1.2 3.2 -1.8 -3.5
Length of working week for main job 0.3 0.4 1.1 -0.5 -0.8 -0.8 -1.0 0.6 -0.5 -0.1 -0.2 -0.6 -1.0 0.3 -0.4 0.2 -0.6
Exposure to tobacco smoke at home 0.6 0.7 3.0 -0.3 -0.0 -0.8 0.3 1.1 0.6 -1.1 -1.0 -0.6 0.5 0.2 1.7 -0.5 -1.3
Breastfed as a baby 0.9 1.1 4.1 1.6 0.4 0.6 1.0 0.9 -1.2 0.4 0.1 1.1 0.4 -1.5 -0.6 2.0 0.9
Tense / ‘highly strung’ 2.1 3.5 6.2 2.5 1.9 2.4 2.2 0.9 -0.7 2.5 0.7 2.2 1.4 -2.3 -0.5 2.3 1.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.8 2.4 1.1 -0.8 -0.5 -0.3 1.2 -0.5 0.2 0.4 0.3 -1.1 -1.2 -1.2 1.5 -0.2
Hair/balding pattern: Pattern 4 0.2 0.5 2.3 -0.1 -0.6 -0.5 -0.8 1.0 -1.5 0.3 0.3 0.3 -1.0 -0.1 0.5 -0.5 -0.6
Birth weight of first child 1.1 2.0 3.4 -1.6 -1.6 -1.8 -1.8 0.4 -0.9 -1.7 -1.0 -1.8 -1.7 1.8 0.2 -1.2 -0.5
Peak expiratory flow (PEF) 0.7 1.6 6.5 0.9 -1.2 -0.9 -0.6 1.6 -0.8 -0.5 -2.5 0.2 -1.5 -1.1 -1.1 1.8 -1.1
Pulse wave reflection index 2.5 3.0 9.4 -2.7 -1.2 -1.4 -1.9 -0.7 1.1 -1.4 -0.7 -1.9 -1.0 3.1 -0.3 -2.7 -1.6
Ever highly irritable/argumentative for 2 days 0.4 0.5 3.3 0.5 -0.1 0.3 -0.1 -0.3 -0.2 0.6 0.8 0.4 -0.1 -0.5 -1.8 1.2 0.8
Loud music exposure frequency 0.6 0.6 2.2 1.1 0.3 0.4 0.2 0.8 0.9 1.1 -0.6 1.1 -0.1 -0.9 -0.5 1.5 0.2
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 6.5 -0.8 0.1 -0.4 -0.0 -0.2 2.5 -0.4 -0.0 -0.4 0.6 0.8 -0.4 -0.8 -0.7
Mouth/teeth dental problems: Bleeding gums 0.2 0.2 1.9 -0.2 -0.2 -0.0 -0.1 -0.1 0.7 -0.1 0.7 0.0 -0.0 0.0 -0.6 -0.0 -1.4
Blood clot in the leg (DVT) 0.1 0.2 0.7 -0.3 0.1 -0.0 0.1 -0.3 0.3 -0.2 0.7 -0.1 0.3 0.1 0.9 -0.7 -0.2
Medication: Paracetamol 1.9 3.1 6.6 -2.0 -2.2 -2.1 -2.0 -1.9 0.5 -2.6 0.1 -2.3 -1.4 2.0 1.6 -1.5 -0.8
Headache pain in last month 0.3 0.5 1.2 -1.1 -0.6 -0.5 -0.8 -0.3 0.5 -0.6 0.1 -0.9 -0.4 0.8 -0.6 -1.0 0.6
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 3.5 1.2 -0.2 0.5 0.0 0.1 -1.9 0.5 0.4 0.7 -0.6 -1.0 -1.2 1.2 -0.5
Glaucoma (self-reported) 0.3 0.4 1.2 0.5 -0.3 0.2 -0.2 -0.8 0.3 0.7 -0.6 1.1 -0.5 -1.0 0.0 0.5 -0.7
Gout (self-reported) 0.5 0.6 2.7 -0.9 0.2 -0.8 0.0 1.6 1.1 -0.8 -0.3 -0.7 0.7 1.0 0.4 -0.7 0.6
Hypothyroidism/myxoedema (self-reported) 0.6 1.1 5.1 1.1 -0.6 0.3 -0.3 -2.3 -1.4 0.1 -0.1 0.6 -1.0 -1.1 0.2 1.8 0.5
Medication: Amlodipine 2.6 3.6 9.4 -1.5 -2.0 -2.1 -1.7 -2.0 1.3 -2.1 -1.4 -1.9 -1.7 1.3 3.1 -1.6 -2.2
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.7 -0.7 0.6 0.2 0.3 0.6 0.8 0.1 0.7 0.1 0.7 0.8 -0.2 -0.1 -0.3
Birth weight 0.7 1.4 3.2 -1.4 -1.1 -1.6 -1.2 0.5 -0.9 -1.5 -0.2 -1.8 -1.2 1.1 -0.5 -1.2 -1.4
Chronic bronchitis/emphysema (mother) 0.5 0.6 2.4 -0.4 -0.1 0.0 -0.2 -1.1 -0.0 -0.1 -1.6 -0.8 0.1 0.5 -1.1 -0.6 1.4
High blood pressure (siblings) 1.7 2.5 5.1 -1.4 -2.0 -2.3 -1.8 -0.4 0.3 -2.2 -1.1 -2.0 -1.7 1.3 1.2 -0.8 -1.8
Forced vital capacity (FVC), Best measure 0.5 1.9 14.4 1.5 -0.6 0.4 0.2 0.6 -0.1 0.2 -3.8 -0.1 -1.0 -2.1 0.1 1.7 0.4
Body fat percentage 0.5 1.9 5.2 -1.4 -1.5 -2.3 -1.4 1.4 0.0 -1.4 -1.3 -1.5 -1.4 1.2 -0.6 -1.6 -1.1
Leg fat percentage (right) 0.5 1.9 4.3 -1.4 -1.6 -2.1 -1.5 0.6 -0.0 -1.4 -1.6 -1.7 -1.4 1.5 -1.0 -1.5 -0.7
Arm fat-free mass (right) 1.2 6.0 11.0 -2.8 -2.2 -3.1 -2.3 -0.5 0.0 -3.0 -2.6 -3.1 -1.8 2.0 2.2 -2.7 -3.3
Exposure to tobacco smoke outside home 0.2 0.2 1.3 -0.4 -0.3 -0.8 -0.2 0.3 0.3 -1.1 -0.1 -0.8 0.2 0.2 0.6 -0.1 0.2
Comparative body size at age 10 1.5 4.0 11.5 -1.8 -2.4 -2.8 -2.1 0.3 -0.3 -2.8 -3.4 -2.5 -2.1 1.0 0.8 -1.5 -1.0
Number of full brothers 0.5 0.7 2.0 0.5 0.8 0.7 0.6 0.8 -0.7 1.1 -1.3 0.9 0.7 -0.3 -0.3 0.3 1.4
Worry too long after embarrassment 0.4 0.7 3.4 1.0 0.2 0.0 0.5 1.0 -1.3 0.2 0.6 0.1 0.1 -1.0 -0.8 0.8 1.9
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 1.9 5.0 1.9 0.4 0.4 0.5 1.9 -0.5 1.5 1.4 1.8 -0.1 -1.8 -1.6 2.2 0.0
Wheeze or whistling in the chest in last year 0.6 1.1 4.0 -0.8 -0.6 -1.2 -0.9 2.0 -1.1 -0.3 -1.9 -0.6 -0.9 0.8 0.2 -0.8 0.9
Number of children fathered 0.6 0.7 2.4 0.6 0.9 1.5 0.7 -0.6 -0.1 1.5 -0.5 1.2 0.7 -0.2 0.3 0.9 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 4.2 -1.1 -1.1 -1.2 -0.9 -0.1 0.0 -2.1 -0.9 -1.4 -0.7 1.3 -0.1 -0.4 -0.5
Age at first live birth 0.9 1.5 3.6 -1.6 -1.3 -1.7 -1.3 0.4 0.7 -1.9 -0.3 -1.4 -0.8 1.5 1.1 -1.4 -0.9
Pulse wave peak to peak time 1.0 1.2 3.1 1.6 0.9 1.1 1.2 -0.3 -0.2 0.9 0.4 1.5 0.9 -1.8 0.3 1.6 -0.2
Health satisfaction 3.0 3.9 10.8 -2.9 -1.7 -2.4 -2.1 -0.8 0.5 -2.0 0.3 -2.2 -1.4 3.3 0.6 -2.4 -2.1
Shortness of breath walking on level ground 1.6 1.9 5.0 -1.9 -1.1 -1.5 -1.4 -0.4 1.1 -1.4 -1.4 -1.6 -0.7 2.2 0.3 -1.8 -1.1
Qualifications: College or University degree 0.8 2.4 8.0 -1.9 -1.4 -1.7 -1.6 0.4 0.6 -1.9 -0.1 -1.5 -1.0 1.5 1.3 -2.0 -2.8
Eye problems/disorders: None of the above 2.1 2.4 6.7 1.2 2.2 2.0 2.3 0.1 1.0 1.3 0.2 1.4 2.6 -0.8 -1.7 1.3 1.4
Mouth/teeth dental problems: Loose teeth 1.2 1.4 2.9 1.0 1.6 1.2 1.7 1.6 0.2 1.3 0.0 1.6 1.6 -0.8 -1.0 0.8 -0.7
Emphysema/chronic bronchitis 0.4 0.5 1.3 -0.6 -1.0 -0.7 -1.1 0.1 0.3 -0.3 -0.8 -0.8 -1.2 0.6 0.0 -0.4 -0.2
Medication for pain relief, constipation, heartburn 2.0 3.5 7.0 1.7 2.4 2.2 2.3 2.7 -1.1 2.5 0.2 1.7 1.8 -1.8 -1.4 1.5 1.5
Neck or shoulder pain in last month 1.3 1.9 6.5 -0.6 -2.2 -1.5 -1.9 0.1 -0.3 -1.0 -1.7 -0.9 -2.5 0.9 -0.8 0.5 -1.6
Medication: Blood pressure 0.3 0.5 1.8 -1.2 -0.1 -0.7 -0.3 -0.9 1.3 -0.7 -0.2 -0.6 0.1 1.1 0.2 -1.0 0.1
Angina (self-reported) 0.5 0.7 1.8 0.5 1.2 1.4 1.1 0.2 0.3 0.9 1.2 0.7 1.1 -0.3 0.7 0.4 0.4
Migraine (self-reported) 2.1 2.6 4.9 -2.0 -1.6 -1.8 -1.9 -1.4 0.2 -1.8 0.3 -2.2 -1.4 2.0 0.5 -2.2 -1.2
Medication: Ibuprofen 0.2 0.3 2.1 -0.2 -0.1 0.2 -0.1 -1.4 -0.2 -0.2 0.9 0.1 0.1 0.8 -0.4 -0.2 -0.3
Medication: Allopurinol 0.4 0.5 1.0 -1.0 0.1 -0.7 -0.1 1.0 0.7 -0.6 0.2 -0.9 0.6 0.8 0.7 -0.9 -0.3
Medication: Omeprazole 0.6 0.7 1.9 -0.6 -0.9 -1.4 -0.7 0.7 0.7 -0.8 -1.1 -0.7 -0.7 1.3 -0.6 0.1 -0.7
Medication: Seretide 50 evohaler 0.3 0.3 2.0 -0.2 0.4 0.4 0.1 -0.5 -0.3 0.9 -1.4 -0.3 0.3 0.2 -0.2 -0.8 0.6
Mean time to correctly identify matches 0.5 1.0 6.9 0.3 0.6 1.1 0.5 -1.7 0.3 1.1 2.6 0.7 0.6 -0.3 0.4 0.4 -0.1
Heart disease (mother) 2.5 3.0 8.0 -1.0 -2.5 -2.8 -2.2 1.0 0.9 -2.1 2.4 -1.8 -2.3 0.4 0.5 -0.3 -1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 3.3 -0.3 -0.2 0.0 -0.5 0.4 -1.8 -0.0 1.2 -0.1 -0.3 0.3 -0.9 -0.2 0.1
Whole body fat mass 0.8 3.5 8.8 -2.0 -2.0 -3.0 -1.9 1.2 -0.0 -2.2 -1.9 -2.2 -1.8 1.5 0.2 -2.2 -1.9
Leg fat mass (right) 0.8 3.1 7.4 -1.9 -1.8 -2.7 -1.7 1.0 -0.3 -2.2 -2.1 -2.2 -1.5 1.6 -0.1 -2.0 -1.5
Arm predicted mass (right) 1.2 5.9 11.1 -2.7 -2.2 -3.1 -2.3 -0.6 0.1 -3.1 -2.7 -3.1 -1.8 2.0 2.0 -2.6 -3.3
Pulse rate, automated reading 1.1 3.5 14.3 1.6 -0.6 -0.8 0.2 3.4 -2.0 -0.1 -3.8 0.2 -1.0 -2.5 -1.2 1.8 1.9
Alcohol intake frequency. 0.2 0.4 2.2 0.0 -0.4 -0.8 -0.3 1.5 -1.1 -0.1 0.2 -0.0 -0.8 -0.2 0.4 0.3 -0.4
Comparative height size at age 10 0.2 1.2 3.2 -0.2 -1.1 -1.2 -0.9 0.9 1.8 -0.4 -1.6 -0.7 -1.3 -0.3 1.4 0.3 -1.6
Number of full sisters 1.8 2.2 4.3 1.8 1.9 2.1 1.9 1.2 -0.6 1.7 0.3 1.8 1.5 -1.5 -0.6 1.2 1.0
Suffer from ‘nerves’ 1.6 2.6 5.2 2.1 1.2 1.4 1.4 2.3 -1.0 2.0 0.5 1.8 0.8 -2.2 -0.3 2.0 1.6
Overall health rating 1.0 2.2 5.5 -2.2 -0.8 -2.4 -1.1 0.2 0.8 -1.8 -0.1 -2.0 -0.5 2.3 0.6 -2.2 -0.3
Chest pain or discomfort 0.9 1.3 6.8 -1.5 -0.2 -1.5 -0.7 2.6 -0.2 -0.5 -0.5 -0.9 -0.3 1.6 -0.6 -1.6 -0.2
Had major operations 0.5 0.6 2.1 0.8 0.2 0.7 0.6 -0.5 -0.1 0.1 1.3 0.3 0.2 -0.7 -1.5 1.1 0.8
Age at last live birth 0.6 0.9 2.2 -1.4 0.0 -0.7 -0.4 1.3 1.4 -0.3 -0.4 -0.3 0.4 1.4 0.8 -1.5 -1.1
Family relationship satisfaction 0.2 0.2 0.8 0.2 -0.5 -0.2 -0.7 -0.4 -0.4 0.4 -0.4 -0.2 -0.6 -0.3 -0.9 0.2 -0.3
Leg pain on walking 1.8 2.2 5.2 -1.1 -2.1 -2.3 -1.9 -0.0 0.5 -1.7 -1.4 -1.5 -1.9 1.4 -1.0 0.3 -1.5
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.0 2.7 -0.9 -1.4 -1.1 -1.5 -0.3 -0.2 -0.8 -0.2 -0.9 -1.6 1.4 0.0 -0.8 -1.1
Commuting to job workplace: Car/motor vehicle 0.4 0.4 1.6 0.7 -0.6 0.6 -0.5 -0.2 -0.6 0.8 -0.9 0.5 -1.3 -0.6 0.4 0.5 -0.2
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 6.4 -0.8 -1.6 -1.1 -1.6 -2.5 -0.4 -1.8 -0.8 -1.0 -1.4 0.1 -0.0 -0.7 -1.4
Medication: Aspirin 0.4 0.5 3.0 -0.0 -0.5 -0.1 -0.5 -1.1 1.0 -0.1 -0.4 0.4 -0.4 -0.1 1.1 -0.1 -1.7
Supplements: Vitamin C 0.3 0.4 2.1 0.0 -0.4 -0.2 -0.4 0.1 -1.5 0.1 0.2 -0.3 -0.8 0.3 -0.3 0.7 -0.9
Knee pain experienced in last month 0.9 1.3 4.6 -1.7 0.1 -0.8 -0.1 -0.2 1.8 -1.2 -0.5 -1.4 0.9 2.1 -1.1 -1.2 0.0
Hypertension (Self-reported) 0.5 1.4 3.7 -1.8 -0.7 -1.9 -1.1 0.6 1.2 -1.3 -0.2 -1.1 -0.4 1.6 0.3 -1.7 -1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.6 0.7 2.0 -0.8 -0.7 -1.4 -0.6 0.6 -0.1 -1.0 -0.9 -1.0 -0.5 0.9 -1.3 -0.5 -0.5
Illnesses of father: Heart disease 1.0 1.3 4.6 -1.3 -0.3 -1.6 -0.5 2.0 2.2 -1.0 0.6 -1.0 0.3 1.1 -0.2 -1.2 -0.4
Illnesses of siblings: Diabetes 0.4 0.4 1.4 0.5 0.9 0.4 0.9 0.6 -0.2 0.4 1.2 0.7 0.8 -0.7 -0.4 0.3 -0.3
Smoking status: Previous 0.3 0.5 1.9 0.9 0.5 0.9 0.5 0.3 -0.1 0.9 0.2 1.2 -0.1 -0.7 1.4 0.2 0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.4 5.2 -1.0 -0.8 -1.3 -0.8 0.3 0.0 -1.6 -1.1 -1.1 -0.5 1.3 2.3 -0.7 -1.6
Whole body fat-free mass 1.4 8.0 14.4 -3.1 -2.7 -3.8 -2.7 -0.4 0.1 -3.7 -3.1 -3.5 -2.2 2.2 2.5 -3.0 -3.6
Leg fat-free mass (right) 1.2 6.5 14.0 -2.6 -2.5 -3.7 -2.4 0.1 -0.8 -3.5 -2.6 -3.0 -2.1 1.8 1.8 -2.7 -3.3
Arm fat percentage (left) 0.5 2.0 5.3 -1.4 -1.5 -2.3 -1.4 1.2 -0.4 -1.5 -1.0 -1.6 -1.4 1.2 -0.6 -1.9 -1.0
Average weekly red wine intake 0.2 0.4 1.5 0.1 -0.3 -0.6 0.1 1.2 0.5 -0.8 1.1 -0.2 0.1 -0.5 0.7 -0.4 0.1
Handedness (chirality/laterality): Left-handed 2.1 2.6 4.1 1.9 1.4 1.2 1.8 1.7 -1.9 0.8 2.0 1.7 1.2 -2.0 -1.1 2.0 0.9
Mood swings 0.3 0.6 1.6 0.4 1.1 0.7 0.9 0.9 0.3 0.8 -0.2 0.5 1.0 0.2 -0.7 0.4 1.2
Loneliness, isolation 0.1 0.1 0.4 -0.0 -0.1 -0.2 -0.1 -0.6 -0.1 -0.2 -0.0 -0.6 -0.2 -0.1 -0.2 -0.2 0.5
Long-standing illness, disability or infirmity 1.6 2.4 6.2 -1.6 -1.8 -2.5 -1.8 0.7 0.5 -1.9 -1.0 -1.3 -1.9 1.7 1.2 -1.3 -1.1
Ever had bowel cancer screening 0.8 0.9 6.9 -0.7 -0.5 -0.5 -0.4 -1.5 2.6 -0.9 -0.1 -0.7 0.1 0.6 0.6 0.1 -0.9
Diabetes diagnosed by doctor 0.3 0.5 3.8 0.2 0.4 -0.3 0.5 1.1 -0.7 -0.3 -0.2 0.2 0.2 0.0 1.9 0.0 -1.0
Ever had stillbirth, spontaneous miscarriage or termination 2.6 2.8 5.5 1.9 1.6 1.4 1.5 1.8 -0.3 2.0 1.3 2.2 1.0 -1.5 -2.4 1.6 1.6
Friendships satisfaction 2.3 2.9 6.4 -1.4 -2.5 -2.3 -2.5 -1.9 1.1 -1.8 -0.5 -1.6 -2.0 1.4 -0.4 -1.0 -1.7
Qualifications: nursing, teaching 0.2 0.4 1.1 0.5 0.3 0.2 0.4 0.8 0.3 0.6 0.8 0.4 0.5 -0.6 -1.1 0.5 0.7
Commuting to job workplace: Walk 2.2 2.4 9.4 1.1 1.8 1.2 1.8 1.0 0.5 1.2 3.1 1.5 1.9 -0.9 -1.7 1.5 -0.2
Eye problems/disorders: Cataract 1.6 1.8 4.5 -1.5 -1.3 -1.5 -1.5 0.5 -0.5 -1.4 -0.4 -1.7 -1.4 0.9 2.0 -2.1 -0.8
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 2.2 -0.5 0.0 0.0 -0.1 0.4 -0.4 0.1 1.5 -0.2 -0.0 0.5 -0.8 -0.4 0.7
Medication for cholesterol 0.4 0.6 2.7 0.6 0.5 1.0 0.4 -0.6 0.1 0.6 0.7 0.9 0.5 -0.6 -1.6 0.8 0.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.5 1.5 1.1 0.5 0.7 0.7 -0.4 -0.5 0.6 1.2 0.9 0.5 -0.9 0.1 1.1 0.2
Back pain experienced in last month 0.3 0.4 0.9 -0.6 -0.3 -0.3 -0.3 -0.4 0.6 -0.6 -1.0 -0.8 -0.0 0.6 -0.9 -0.3 0.9
Mineral and other dietary supplements 0.9 1.3 3.6 -1.2 -0.7 -1.5 -0.6 0.6 0.5 -1.7 -1.3 -1.1 -0.1 0.9 1.6 -1.9 -0.3
Breast cancer (self-reported) 0.5 0.6 1.8 0.8 -0.5 -0.7 -0.2 0.5 -0.4 0.1 -1.0 0.1 -0.4 -1.3 1.3 0.9 -0.7
Asthma (self-reported) 0.2 0.3 1.7 -0.1 0.2 0.6 0.1 0.4 -1.0 0.8 -1.3 0.6 -0.1 0.4 0.2 0.3 -0.2
Osteoporosis (self-reported) 1.2 1.5 4.1 -1.9 -0.3 -1.2 -0.7 -0.1 1.5 -1.4 -1.2 -1.2 -0.1 2.0 -0.2 -2.0 -0.5
Osteoarthritis (self-reported) 0.4 0.5 2.6 0.6 0.7 -0.0 0.7 1.6 0.7 0.5 -0.4 0.4 0.7 -0.4 0.7 0.2 0.5
Medication: Aspirin 0.4 0.5 2.2 0.1 -0.7 -0.2 -0.6 -0.9 1.0 -0.2 -1.0 0.3 -0.6 -0.2 0.8 0.1 -1.5
Medication: Gliclazide 0.5 0.6 2.8 -0.8 -0.3 -0.8 -0.4 0.8 1.0 -0.9 -0.3 -0.8 -0.0 0.6 1.7 -0.7 -0.4
Illnesses of father: None of the above (group 1) 3.2 4.0 8.4 2.8 1.6 2.6 2.1 -1.1 -2.0 2.0 0.3 2.4 1.3 -2.9 -0.6 2.2 1.9
Smoking status: Current 0.7 1.0 3.4 -1.1 -0.4 -0.6 -0.7 -1.3 -0.1 -0.9 -1.8 -1.2 0.0 1.3 -1.5 -0.9 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 2.0 1.0 1.0 0.9 1.1 0.8 0.7 0.9 -0.0 0.7 0.7 -1.4 -0.1 1.0 0.2
Whole body water mass 1.3 7.3 13.0 -2.9 -2.6 -3.6 -2.6 -0.4 0.1 -3.5 -2.9 -3.4 -2.1 2.1 2.4 -2.9 -3.5
Leg predicted mass (right) 1.1 6.0 13.2 -2.6 -2.4 -3.6 -2.3 0.1 -0.7 -3.5 -2.5 -3.0 -2.0 1.7 1.8 -2.7 -3.1
Arm fat mass (left) 0.8 3.4 8.1 -1.9 -2.0 -2.8 -2.0 0.9 -0.4 -2.1 -1.8 -2.2 -2.0 1.5 0.3 -2.2 -2.0
Number of self-reported non-cancer illnesses 0.7 1.2 3.6 -0.5 -1.7 -1.8 -1.4 0.3 -0.7 -1.4 -0.2 -1.0 -1.9 0.1 -0.8 0.1 0.7
Average weekly champagne plus white wine intake 0.9 1.2 2.3 1.4 1.2 1.5 1.3 0.2 -0.4 1.0 0.2 1.4 1.1 -1.4 -0.5 1.3 1.0
Miserableness 0.8 1.4 4.4 1.0 1.1 0.7 1.2 1.0 1.1 1.0 -0.4 0.7 1.2 -0.6 -2.1 1.3 2.0
Guilty feelings 1.5 2.3 4.6 1.3 2.0 1.5 2.0 2.2 0.6 1.7 1.2 1.4 1.9 -1.0 -0.8 1.0 1.6
Wears glasses or contact lenses 0.4 0.5 1.8 0.4 -1.2 -0.4 -1.0 -0.9 0.5 -0.1 0.2 -0.6 -1.3 -0.7 0.7 -0.3 -0.5
Ever taken oral contraceptive pill 0.4 0.5 1.3 0.1 0.8 0.6 0.7 -0.8 1.1 0.4 1.1 0.5 1.1 0.2 0.4 -0.4 -0.4
Hearing aid user 1.6 1.8 3.8 1.6 1.2 1.6 1.2 1.9 0.3 1.8 0.8 1.9 0.6 -1.6 -0.1 1.6 -0.8
Mother’s age at death 0.5 0.7 2.8 0.3 0.7 0.5 0.8 0.8 1.7 0.3 -0.1 -0.0 1.2 -0.9 1.3 -0.2 -0.4
Financial situation satisfaction 0.6 0.8 1.7 1.2 0.9 0.9 1.1 0.5 -0.5 0.9 0.9 0.8 0.8 -0.8 -0.4 1.1 1.3
Tinnitus: Yes, now most or all of the time 1.9 2.2 5.2 -1.6 -1.5 -2.3 -1.4 0.5 0.7 -2.1 -1.6 -1.8 -1.3 1.4 1.3 -1.5 -0.7
Commuting to job workplace: Public transport 0.7 0.8 3.8 -1.5 0.2 -0.9 -0.0 0.2 0.1 -1.0 0.0 -0.9 0.7 1.3 0.0 -2.0 0.1
Eye problems/disorders: Glaucoma 0.8 1.0 3.4 1.2 0.5 0.7 0.6 -0.1 0.9 1.2 0.5 1.8 0.4 -1.8 -0.1 1.1 0.0
Medication: Blood pressure 1.3 2.5 6.2 -1.2 -1.9 -2.5 -1.9 1.1 0.2 -1.6 -1.2 -1.4 -1.8 0.9 2.0 -1.0 -1.8
Pain type(s) experienced in last month: Hip pain 0.6 0.7 2.5 -1.3 -0.4 -0.9 -0.5 0.8 0.3 -0.6 -0.4 -1.1 -0.1 1.6 1.0 -0.7 -0.7
Supplements: Fish oil (including cod liver oil) 0.4 0.5 1.1 0.5 1.1 1.0 0.9 -0.3 -0.0 1.1 1.0 0.6 0.8 -0.3 -0.5 0.8 0.4
High cholesterol (Self-reported) 0.3 0.5 1.5 -0.6 -0.1 -0.8 -0.3 1.2 0.4 -0.1 -0.9 -0.9 0.0 0.4 -0.6 -0.7 1.2
Medication: Bendroflumethiazide 0.5 0.7 1.9 -1.2 0.1 -1.2 -0.2 1.4 0.8 -0.4 -0.6 -0.5 0.2 1.1 1.0 -1.0 -0.7
Medication: Paracetamol 1.9 2.9 5.8 -1.8 -2.0 -1.8 -1.8 -1.8 0.4 -2.4 0.3 -2.3 -1.3 1.9 2.1 -1.5 -1.0
Medication: Lisinopril 0.5 0.6 1.6 -0.1 -1.2 -1.0 -1.2 -0.1 -1.0 -0.8 0.1 -0.4 -1.2 -0.1 -0.4 0.3 1.1
Medication: Atorvastatin 0.8 1.0 3.0 -1.3 -0.2 -0.9 -0.5 -0.0 1.2 -0.8 -1.6 -1.7 0.1 1.1 0.1 -1.5 1.0
Illnesses of father: High blood pressure 0.7 0.8 2.7 -1.0 -0.3 -1.1 -0.4 1.0 0.1 -1.0 -0.3 -1.0 0.0 1.2 1.2 -0.7 -1.7
Alcohol drinker status: Never 1.2 1.5 4.6 1.5 0.5 0.6 0.6 1.4 -1.3 1.0 0.6 1.4 -0.0 -1.9 -1.4 2.1 0.8
Ever smoked 0.7 1.2 2.2 -1.1 -1.1 -1.4 -1.2 -0.8 0.9 -1.4 -1.5 -1.3 -1.0 1.1 0.2 -1.4 0.3
Basal metabolic rate 1.3 7.3 13.6 -2.9 -2.6 -3.7 -2.6 -0.2 -0.0 -3.5 -2.9 -3.4 -2.2 2.2 2.2 -2.9 -3.4
Leg fat percentage (left) 0.4 1.6 3.2 -1.4 -1.3 -1.8 -1.4 0.5 -0.2 -1.2 -1.4 -1.3 -1.2 1.5 -0.8 -1.6 -1.0
Arm fat-free mass (left) 0.9 4.8 9.9 -2.4 -2.0 -2.8 -2.1 -0.3 -0.1 -2.6 -2.7 -2.6 -1.7 1.8 1.8 -2.2 -3.1
Number of operations (self-reported) 0.8 1.2 2.3 -0.8 -1.5 -1.2 -1.3 -0.9 0.7 -1.3 1.1 -1.2 -1.4 1.3 0.4 -0.5 -0.9
Average weekly beer plus cider intake 0.5 0.8 4.0 0.7 0.3 -0.0 0.4 1.2 1.4 0.8 -2.0 0.8 0.0 -0.5 -0.7 0.8 0.3
Irritability 0.7 1.1 3.7 1.1 1.0 1.4 0.7 0.9 -0.5 1.8 0.9 1.9 0.5 -0.7 -0.2 1.3 -0.1
Risk taking 2.2 3.2 8.4 1.8 2.3 2.9 2.0 0.4 -0.4 2.5 2.0 2.3 2.0 -1.2 -0.1 1.4 0.6
Ever had prostate specific antigen (PSA) test 2.7 3.2 10.6 -1.7 -2.1 -1.6 -2.1 -3.3 0.0 -1.9 -0.2 -1.8 -2.0 1.9 -0.3 -1.2 -1.9
Fractured/broken bones in last 5 years 1.4 1.9 3.9 1.2 2.0 1.6 1.9 0.2 0.6 1.5 1.3 1.2 2.0 -1.1 -0.9 0.9 1.3
Age started oral contraceptive pill 0.7 0.9 6.2 -0.2 0.6 -0.4 0.4 2.5 0.2 0.3 1.6 0.4 0.7 -0.6 1.1 -0.5 0.3
Diastolic blood pressure, automated reading 0.4 1.1 4.8 0.8 0.5 0.2 0.7 2.2 -0.2 0.5 -2.2 0.9 0.5 -1.0 -0.4 0.2 1.4
Ever depressed for a whole week 0.7 0.9 2.1 0.6 1.2 0.8 1.2 -0.2 0.3 0.3 1.4 1.2 1.5 -0.5 -0.7 1.2 0.5
Unable to work because of sickness or disability 1.9 2.5 6.2 -1.5 -1.8 -2.5 -1.7 -0.5 0.5 -1.9 -2.2 -1.9 -1.7 1.4 0.5 -1.4 -0.4
Commuting to job workplace: Cycle 1.0 1.3 2.3 -1.4 -0.1 -0.6 -0.4 -0.4 1.3 -1.1 1.4 -1.3 0.3 1.5 1.5 -1.4 -1.4
Myopia 2.6 3.8 6.2 -2.0 -2.5 -2.3 -2.5 -1.8 0.7 -2.5 -2.2 -2.2 -2.3 1.7 -0.1 -1.4 -1.1
Vascular/heart problems diagnosed by doctor 0.6 1.7 3.9 2.0 0.5 1.9 0.9 -0.7 -1.3 1.4 0.7 1.1 0.1 -1.8 -1.3 1.8 1.4
Cholesterol lowering medication 0.6 0.8 3.6 0.6 -0.9 -1.2 -0.5 1.0 -1.2 -0.2 -1.9 -0.8 -1.0 -0.5 0.0 0.3 0.7
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 3.5 -1.1 -1.1 -1.5 -0.9 0.4 0.2 -1.4 -0.6 -1.3 -0.8 1.9 -0.0 -0.2 -1.4
Pain experienced in last month 0.5 0.9 4.0 1.5 0.5 0.7 0.8 -0.2 -0.8 0.5 0.3 1.1 0.2 -2.0 0.8 1.2 -0.0
Supplements: Calcium 1.0 1.1 3.5 -1.4 -0.5 -0.8 -0.6 -1.2 1.9 -0.9 -0.1 -1.0 0.0 1.4 0.2 -1.3 -1.2
Basal cell carcinoma (self-reported) 0.1 0.1 0.2 -0.0 0.4 0.2 0.5 -0.1 0.2 0.1 -0.1 0.2 0.5 -0.3 -0.1 0.2 0.2
Heart attack/myocardial infarction (self-reported) 1.6 2.0 4.2 -2.0 -1.1 -1.5 -1.3 -0.9 1.0 -1.7 -2.1 -1.9 -0.5 1.9 0.8 -1.6 -0.2
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 0.6 -0.3 0.1 -0.1 0.2 -0.3 0.5 -0.3 0.7 -0.1 0.4 -0.0 0.8 -0.7 -0.2
Heart disease (siblings) 0.7 0.8 2.9 -0.4 0.7 -0.0 0.4 1.2 1.6 0.0 1.7 0.2 1.3 0.4 -0.3 -0.6 1.0
Alcohol drinker status: Previous 0.8 1.0 3.6 0.8 0.9 0.7 0.8 1.9 -0.4 1.0 1.3 1.2 0.5 -1.2 1.0 -0.0 -0.6
Pack years of smoking 0.9 1.3 4.1 0.1 -1.7 -1.2 -1.3 -0.6 -0.9 -1.0 -2.0 -1.1 -1.9 -0.3 0.0 0.7 -0.8
Impedance of whole body 0.4 1.9 3.9 1.2 1.2 1.5 1.2 1.0 2.0 1.7 1.6 1.7 1.2 -0.8 -0.8 1.5 1.4
Leg fat mass (left) 0.7 2.8 6.3 -1.9 -1.6 -2.5 -1.6 0.8 -0.5 -2.0 -1.9 -2.0 -1.4 1.6 0.0 -2.1 -1.6
Arm predicted mass (left) 1.1 5.6 10.2 -2.6 -2.2 -3.1 -2.4 -0.4 -0.1 -2.8 -2.9 -2.9 -1.9 2.0 1.7 -2.3 -3.2