Hub : Genes

TECPR2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0880 0.0310 7.1e-05 0.059 0.032 0.024 0.037 0.044 9.6e-08 7.4e-05 5.4e-04 2.3e-05 3.9e-06
2 GTEx Artery Aorta 0.2430 0.0590 7.4e-07 0.163 NA 0.120 NA 0.139 2.7e-09 NA 4.1e-07 NA 4.4e-08
3 GTEx Artery Tibial 0.1110 0.0400 5.1e-04 0.088 NA 0.082 NA 0.087 2.0e-07 NA 5.2e-07 NA 2.3e-07
4 GTEx Cells Transformed fibroblasts 0.1230 0.0460 1.9e-03 0.067 NA 0.012 NA 0.033 1.0e-05 NA 3.9e-02 NA 1.5e-03
5 METSIM Adipose 0.0480 0.0182 5.5e-04 0.020 0.021 0.023 0.022 0.027 4.6e-04 2.9e-04 1.6e-04 2.3e-04 5.4e-05
6 TCGA Colon Adenocarcinoma 0.1790 0.0740 5.0e-04 0.045 0.017 0.022 NA 0.039 1.3e-03 3.5e-02 1.9e-02 NA 2.7e-03
7 TCGA Kidney Renal Clear Cell Carcinoma 0.0492 0.0261 1.7e-03 0.012 0.031 0.019 NA 0.022 1.3e-02 1.6e-04 2.8e-03 NA 1.5e-03
8 TCGA Prostate Adenocarcinoma 0.0421 0.0252 6.5e-03 0.004 0.005 0.004 NA -0.002 1.1e-01 9.0e-02 1.2e-01 NA 6.2e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.9 1.5 3.0 -1.2 1.4 1.6 -0.4 1.7 0.1 1.1 1.3
Bipolar Disorder or Schizophrenia 0.3 0.7 2.6 -0.7 0.2 0.6 -0.2 0.9 0.3 1.6 1.1
Depressed Affect (Nagel 2018) 2.3 4.8 11.8 2.7 -2.0 -2.0 2.4 -1.7 0.9 3.4 1.2
Depression (Nagel 2018) 1.3 1.9 8.0 1.2 -1.0 -1.0 1.0 -1.2 2.8 1.2 -0.2
Intelligence (Savage-Jansen 2018) 0.5 1.4 3.6 -1.3 1.3 1.0 -1.0 1.9 0.4 0.6 1.3
Neuroticism (Nagel 2018) 2.0 4.7 8.4 2.9 -2.3 -2.4 1.6 -2.2 2.3 2.4 -0.0
Schizophrenia (2018) 0.1 0.3 1.3 0.2 -0.8 -0.5 0.0 -0.2 0.3 1.1 0.4
Schizophrenia vs Biploar Disorder 0.3 0.4 0.8 0.6 -0.9 -0.8 0.7 -0.9 0.2 -0.2 -0.4
Worry (Nagel 2018) 1.5 3.1 7.3 2.2 -1.8 -1.9 0.9 -2.0 2.7 0.7 -1.0
Alzheimer’s Disease (in mother) 3.5 4.1 8.8 2.2 -3.0 -2.9 -0.6 -2.4 1.1 -0.3 -1.8
Alzheimer’s Disease (in father) 1.0 1.1 2.5 0.8 -1.2 -1.0 -1.0 -1.1 0.9 -0.6 -1.6
Alzheimer’s Disease (including proxy) 2.4 3.6 7.2 1.9 -2.7 -2.5 -0.8 -2.0 1.6 -0.5 -2.0
Crohns Disease (2017) 0.6 1.3 4.3 -2.1 1.2 1.5 -0.6 0.4 -1.4 0.0 -0.2
Irritable Bowel Disease (IBD) 1.4 3.4 7.9 -2.8 2.4 2.5 -0.5 1.9 -1.2 1.0 1.1
Ulcerative Colitis (UC) 1.7 3.2 5.4 -2.3 2.2 2.2 -0.5 2.3 -0.6 1.3 1.8
Major Depression (MDD) 1.6 1.9 5.7 -0.7 1.0 0.9 0.9 1.2 -0.7 2.2 2.4
Reaction Time 1.6 3.1 9.2 0.2 -1.3 -1.3 -3.0 -1.3 -1.2 -2.1 -2.2
Verbal and Numeric Reasoning (VNR) 0.3 0.7 1.3 -1.1 1.0 0.9 -0.9 1.0 0.4 -0.4 0.1
Breast Cancer 0.2 0.6 2.4 0.2 -0.7 -0.8 -1.6 -0.2 -1.0 -0.2 -0.3
Ovarian Cancer 0.7 0.9 3.2 1.4 -0.7 -0.7 0.6 -0.7 1.8 0.4 -0.5
Prostate Cancer 0.1 0.2 0.5 0.5 -0.3 -0.4 0.2 -0.4 -0.0 -0.7 -0.4
Age at First Birth 0.9 1.3 2.0 -1.3 1.1 1.1 1.1 1.4 -0.8 0.6 1.3
Bipolar Disorder (2011) 1.5 1.5 2.4 -1.1 1.1 1.4 -0.2 1.5 -0.8 1.5 1.4
Body Mass Index (BMI) (2010) 0.7 0.9 2.9 0.6 -0.4 -0.6 -0.5 -1.2 -0.0 -1.7 -1.4
Coronary Artery Disease (CAD) 1.3 1.5 2.8 -1.6 1.5 1.7 -1.1 1.3 0.6 0.8 0.8
Crohns Disease (2012) 0.3 0.4 1.5 -0.4 -0.3 -0.1 -0.8 -0.9 0.2 -0.3 -1.2
Mean Putamen Volume 0.8 0.9 2.3 -0.8 1.2 1.0 0.9 -0.1 -1.5 -1.0 -0.3
Fasting Glucose 0.7 0.8 2.3 0.2 -0.7 -0.4 -0.4 -1.0 -1.3 -1.5 -1.0
HbA1C 1.0 1.1 2.3 -1.3 1.3 1.5 0.3 1.1 -0.7 0.5 1.2
HDL Cholesterol 0.1 0.1 0.5 -0.2 -0.3 -0.2 -0.7 -0.2 0.1 0.4 0.1
LDL Cholesterol 0.1 0.1 0.5 0.2 0.3 0.2 0.7 0.1 0.4 0.3 -0.1
Lupus 0.5 0.7 1.5 -1.2 0.8 1.2 -0.9 0.9 -0.5 0.1 0.3
Neuroticism (2016) 0.7 1.0 1.9 1.3 -1.4 -1.4 0.0 -1.1 -0.0 1.2 -0.1
Primary Biliary Cirrhosis 0.8 1.1 4.1 -0.1 -0.2 -0.0 -1.6 -0.4 -2.0 -1.3 -0.7
Rheumatoid Arthritis 0.3 0.4 1.3 0.1 0.6 0.5 1.1 0.5 -0.8 -0.1 0.4
Schizophrenia (2014) 0.2 0.5 2.6 0.4 -0.9 -0.3 0.5 -0.3 -0.1 1.6 0.5
Triglycerides 0.5 0.8 3.1 0.5 0.0 -0.0 0.4 -0.8 0.4 -1.8 -1.5
Type 2 Diabetes (T2D) (2012) 0.8 1.0 3.9 -0.7 0.6 0.3 -1.3 0.2 -0.0 -2.0 -1.1
Ulcerative Colitis 1.3 1.9 4.5 -2.1 1.9 1.8 -0.2 1.7 0.2 0.1 1.0
Blood Eosinophil Count 0.7 5.5 10.4 -3.2 3.1 3.2 -0.7 1.4 -2.4 -2.2 -0.7
Blood Platelet Count 6.7 78.0 139.2 -8.2 8.4 8.7 -1.6 11.3 -4.6 10.9 11.8
Blood Red Count 0.3 3.2 6.6 2.4 -2.4 -2.6 -1.5 -0.9 1.8 0.3 -0.9
Blood White Count 0.2 1.5 4.9 0.8 -1.1 -1.2 -2.2 -0.7 -1.2 -1.2 -0.8
Heel T-Score 0.1 1.1 3.2 -0.8 0.9 1.1 1.3 0.1 -1.8 0.2 0.9
BMI 0.3 1.7 6.6 0.8 -0.4 -0.3 -1.0 -1.0 -2.6 -1.9 -0.8
Height 1.7 33.4 60.4 -6.8 5.6 6.2 -3.0 7.8 -0.8 6.1 6.5
Waist Hip Ratio (WHR) 0.5 2.1 4.0 -1.4 0.9 1.1 -1.7 1.7 -2.0 0.8 1.6
Systolic Blood Pressure 0.3 1.3 5.6 0.5 -0.4 -0.0 0.8 1.0 0.3 2.4 1.6
Smoking Status 0.2 0.5 2.3 -0.2 -0.3 -0.2 -1.1 -0.3 -1.5 -0.1 -0.5
Allergy or Eczema 1.7 4.4 17.4 0.1 -0.3 -0.6 -1.9 -1.3 0.3 -4.2 -3.4
Cardiovascular Disease 0.2 0.8 3.0 0.1 0.3 0.2 -1.0 -0.3 -1.7 -1.2 -0.6
Hypothyroidism (self reported) 0.2 0.5 0.9 -1.0 0.7 0.7 -0.8 -0.1 -0.3 -0.7 -0.9
Respiratory disease 0.6 1.3 3.0 -1.7 1.4 1.3 -1.1 1.1 -0.9 -0.5 0.2
Type 2 Diabetes (T2D) (2018) 0.4 0.7 4.2 -0.3 0.4 0.6 -0.1 -0.3 -2.0 -0.7 -0.1
Lung FEV1/FVC ratio 0.8 3.9 7.7 -2.5 2.7 2.8 1.4 1.2 -2.3 -1.1 0.5
Lung FVC 0.7 3.3 5.6 -0.7 1.6 1.6 2.4 1.6 2.1 2.2 1.9
Neuroticism 1.7 4.0 7.4 2.7 -2.5 -2.5 0.8 -2.2 1.1 2.3 0.1
Chronotype (morning person) 0.5 1.2 3.5 -1.3 1.3 1.3 -0.2 0.4 -1.9 -0.6 -0.1
Hair Pigment 0.1 1.5 3.5 -0.9 0.6 0.9 -0.5 1.4 -1.8 1.2 1.9
Tanning 0.0 0.5 1.7 -0.2 0.1 -0.0 -0.9 -0.5 -0.2 -1.1 -1.3
Hand grip strength (left) 4.4 11.7 18.5 -1.9 3.5 3.5 3.3 4.3 3.5 3.1 3.8
Number of treatments/medications taken 0.5 0.9 2.8 -0.2 -0.1 -0.3 -1.7 -0.6 -1.5 -0.9 -0.9
Average weekly spirits intake 0.1 0.1 0.1 0.0 0.3 0.3 0.3 0.4 0.0 -0.0 0.4
Sensitivity / hurt feelings 2.5 4.3 15.1 0.1 0.7 0.8 3.1 0.7 1.4 3.9 2.5
Frequency of depressed mood in last 2 weeks 1.4 1.9 6.6 1.2 -1.0 -1.1 0.8 -0.4 2.6 2.0 0.3
Hearing difficulty/problems: Yes 0.6 0.9 2.1 0.6 -0.8 -0.8 -0.5 -1.2 -0.7 -1.5 -1.3
Relative age of first facial hair 0.3 0.6 1.9 -0.5 -0.7 -0.5 -1.4 -0.8 0.3 -0.4 -1.1
Other serious medical condition/disability diagnosed by doctor 3.2 4.1 9.9 -3.1 2.4 2.7 -1.6 2.1 -1.3 0.5 1.1
Ever used hormone-replacement therapy (HRT) 1.1 1.4 3.5 -0.5 -0.3 -0.3 -1.2 -1.1 -1.6 -1.9 -1.5
Ever had hysterectomy (womb removed) 1.6 1.8 3.8 2.0 -1.5 -1.5 1.4 -1.0 0.2 1.7 0.8
Systolic blood pressure, automated reading 0.2 0.5 1.2 0.8 -1.0 -0.8 -0.2 0.2 -0.0 1.1 0.3
Eye problems/disorders: Diabetes related eye disease 2.6 2.9 5.7 -2.4 1.6 1.8 -1.7 1.9 -2.1 0.0 0.8
Angina 1.0 1.3 3.1 -1.7 0.9 1.1 -1.6 0.5 -1.5 0.1 -0.1
Medication for hormone replacement therapy 0.8 0.9 2.6 -0.6 0.8 0.9 1.6 0.5 0.9 0.7 0.8
Vitamin and mineral supplements 0.9 1.3 4.3 -0.9 0.8 1.1 -0.1 1.4 -2.1 0.2 1.1
Supplements: Zinc 1.5 1.6 4.0 -1.8 2.0 1.8 0.1 0.8 0.2 -1.3 -0.4
Medication: Co-codamol 0.2 0.2 0.6 -0.7 0.1 0.2 -0.7 0.4 -0.5 -0.6 0.2
Medication: Metformin 0.9 1.2 6.1 -0.1 0.1 0.1 -0.9 -0.6 -2.5 -1.3 -0.8
Diabetes (father) 0.5 0.6 1.4 1.0 -1.0 -1.0 0.4 -0.5 -1.2 0.1 0.3
Diabetes (mother) 0.5 0.7 1.6 0.5 -0.3 -0.4 -1.1 -0.4 -1.0 -1.3 -0.8
Severe depression (siblings) 1.5 1.7 4.9 1.0 -0.7 -0.4 0.4 0.8 2.2 2.2 1.3
Pack years adult smoking proportion 1.3 2.0 5.3 -0.8 -0.1 -0.1 -1.7 -0.8 -2.3 -2.1 -1.5
Impedance of leg (right) 0.6 2.8 6.3 2.3 -2.4 -2.5 0.5 -1.8 0.6 0.8 -0.6
Leg fat-free mass (left) 1.6 8.5 15.1 -3.2 3.5 3.9 0.0 3.8 -0.3 2.3 3.2
Trunk fat percentage 0.3 1.1 4.4 -0.2 -0.6 -0.2 -1.8 -0.5 -2.1 -0.4 -0.2
Hand grip strength (right) 4.1 11.1 17.4 -1.7 3.3 3.2 3.2 4.2 3.2 3.4 3.9
Townsend deprivation index at recruitment 0.9 1.3 6.2 -0.7 -0.3 -0.3 -2.5 -0.5 -0.6 -1.2 -1.2
Current tobacco smoking 0.7 1.1 5.0 -1.1 0.7 0.7 -1.1 0.7 -2.2 -0.2 0.3
Average weekly fortified wine intake 0.7 0.8 2.0 -1.1 0.6 0.7 -0.5 -0.2 -1.2 -1.4 -0.7
Maternal smoking around birth 0.7 0.9 2.3 -0.4 0.4 0.3 -1.2 1.4 0.3 1.5 1.1
Fed-up feelings 0.6 1.1 4.2 0.7 -0.8 -0.6 1.1 -0.9 -0.3 2.0 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 5.7 -0.2 0.2 0.0 -0.4 -0.0 2.4 -0.2 -0.7
Relative age voice broke 0.5 0.8 2.7 -1.6 0.9 1.0 -1.0 0.7 0.0 -0.7 -0.2
Taking other prescription medications 1.4 2.1 6.7 -0.1 -0.6 -0.7 -2.6 -0.9 -2.5 -1.0 -1.1
Age when periods started (menarche) 1.1 2.6 4.5 -1.7 1.6 1.8 1.0 1.8 -0.6 1.7 2.1
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 2.5 0.2 -0.3 -0.2 0.4 -1.2 -1.6 -0.8 -0.8
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.6 1.1 1.0 -0.6 -0.6 1.0 -1.0 0.0 -0.4 -0.8
Tinnitus: Yes, but not now, but have in the past 3.2 3.4 5.2 -1.6 2.1 2.1 2.0 1.8 -1.2 1.5 2.3
Qualifications: CSEs or equivalent 1.1 1.4 5.4 -0.3 1.3 1.2 2.3 0.9 -0.1 0.5 1.2
Serious illness, injury or assault to yourself 0.2 0.3 1.4 0.2 -0.4 -0.3 -1.2 -0.5 -0.3 0.0 -0.4
High blood pressure 0.3 0.9 3.3 0.5 -0.5 -0.4 -0.9 -0.7 -1.8 -1.2 -0.8
Hayfever, allergic rhinitis or eczema 1.5 3.2 7.1 1.6 -1.3 -1.6 -0.2 -1.8 1.6 -2.4 -2.7
Multivitamins +/- minerals 0.8 1.0 2.4 1.1 -0.7 -0.9 1.3 -1.2 1.5 0.3 -0.5
Stomach or abdominal pain in last month 0.2 0.2 0.6 0.7 -0.4 -0.4 0.1 -0.8 -0.3 0.5 -0.1
Supplements: Glucosamine 0.1 0.2 0.6 -0.2 0.3 0.2 0.6 -0.3 0.8 0.2 -0.1
Diverticular disease/diverticulitis (self-reported) 1.6 1.8 4.8 -0.5 0.8 0.9 1.2 1.1 -1.1 2.2 2.1
Medication: Atenolol 2.8 3.6 8.0 -2.3 2.1 2.1 -0.1 1.9 -2.8 0.2 1.6
Medication: Levothyroxine sodium 0.7 1.1 2.3 -1.4 1.5 1.5 0.4 0.4 -1.1 -0.9 -0.0
Sitting height 0.8 5.8 9.4 -2.2 2.6 2.8 1.3 2.8 -0.4 2.7 3.1
Chronic bronchitis/emphysema (father) 1.1 1.3 2.3 0.0 0.7 0.5 1.3 1.5 1.4 1.3 1.5
High blood pressure (mother) 1.1 1.6 4.0 -0.3 1.0 1.1 1.5 1.2 -0.4 1.5 2.0
Body mass index (BMI) 0.3 1.1 4.5 0.4 -0.3 -0.1 -0.5 -1.0 -2.1 -1.6 -0.7
Impedance of leg (left) 0.4 2.1 5.2 2.0 -2.1 -2.3 0.3 -1.6 0.2 0.8 -0.4
Leg predicted mass (left) 1.6 8.3 14.6 -3.1 3.4 3.8 0.1 3.8 -0.3 2.3 3.3
Trunk fat mass 0.3 1.2 3.8 -1.0 0.6 1.0 -1.1 0.7 -2.0 0.6 1.1
Waist circumference 0.7 2.7 10.4 -1.5 1.3 1.7 -1.5 1.2 -3.2 -0.2 1.0
Number of incorrect matches in round 0.7 1.2 3.1 0.6 0.4 0.7 1.7 0.5 0.3 1.8 1.5
Past tobacco smoking 0.3 0.5 1.9 -0.2 0.9 0.7 1.4 0.5 0.5 -0.2 0.4
Alcohol usually taken with meals 1.2 1.9 3.5 -1.9 1.8 1.7 0.1 1.7 1.3 0.4 0.7
Nervous feelings 0.2 0.3 1.0 0.6 -0.4 -0.5 -0.1 -0.5 1.0 0.5 -0.3
Frequency of tenseness / restlessness in last 2 weeks 2.1 3.3 6.5 2.0 -2.1 -2.1 -0.9 -0.9 2.6 2.3 0.0
Hearing difficulty/problems with background noise 1.1 1.8 3.6 1.3 -1.3 -1.4 -0.5 -1.5 0.2 -1.6 -1.9
Hair/balding pattern: Pattern 2 1.3 1.6 4.1 2.0 -1.6 -1.6 1.0 -0.8 0.8 1.3 0.2
Had menopause 1.2 1.5 6.2 -0.8 0.7 0.8 -0.6 -0.5 -2.5 -1.7 -0.7
Had other major operations 0.7 0.9 4.1 -0.4 0.5 0.4 -0.4 0.4 -2.0 -1.4 0.1
Forced vital capacity (FVC) 2.6 9.9 21.0 -0.7 1.9 2.0 3.2 3.3 3.7 4.6 4.0
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.3 0.8 -0.4 -0.4 1.1 -0.8 0.3 -0.6 -0.9
Ever unenthusiastic/disinterested for a whole week 1.3 1.6 4.0 1.2 -1.8 -1.8 -2.0 -0.7 -0.6 0.1 -0.4
Qualifications: None of the above 0.4 0.9 3.5 -1.0 0.8 1.0 0.7 -0.2 -1.9 -0.6 -0.0
Financial difficulties in last 2 years 0.2 0.3 0.5 -0.7 0.5 0.4 0.0 0.5 0.4 0.6 0.6
Mouth/teeth dental problems 0.4 0.7 4.9 -0.0 -0.1 -0.1 -0.6 0.1 2.2 -0.1 -0.4
Heart attack 0.3 0.4 0.7 -0.9 0.6 0.6 -0.8 0.0 -0.6 -0.5 -0.6
Allergy 0.3 0.7 2.4 -0.4 0.2 0.4 0.3 0.7 -0.3 1.5 1.5
Pain all over the body in last month 0.4 0.4 1.9 0.9 -0.2 -0.3 1.4 -0.5 -0.2 0.5 0.0
Diabetes (self-reported) 0.7 1.1 5.3 -0.1 -0.4 -0.2 -1.0 -0.6 -2.3 -1.0 -0.7
Hayfever/allergic rhinitis (self-reported) 3.7 4.9 13.1 0.6 -1.1 -1.3 -1.5 -2.0 2.2 -3.4 -3.6
Medication: Ramipril 1.6 2.1 5.3 0.9 -0.8 -0.9 -0.5 -1.9 -0.4 -2.2 -2.3
Medication: Simvastatin 0.2 0.3 1.0 0.8 -0.5 -0.6 0.2 -0.5 -1.0 -0.2 -0.0
Fluid intelligence score 0.2 0.3 1.6 0.5 -0.5 -0.6 -1.3 0.1 0.2 -0.3 -0.3
Illnesses of siblings 0.6 0.9 3.7 0.9 0.1 -0.2 1.9 0.0 0.9 1.1 0.7
Neuroticism score 0.9 1.9 8.9 1.0 -0.8 -0.8 1.0 -0.6 1.1 3.0 1.2
Weight 0.6 3.0 5.2 -1.8 1.9 2.3 -0.7 1.9 -1.8 1.0 1.9
Impedance of arm (right) 0.3 1.4 3.4 0.2 -1.5 -1.4 -1.7 -0.1 1.9 0.9 -0.4
Arm fat percentage (right) 0.2 0.9 2.6 -0.1 -0.6 -0.2 -1.6 -0.6 -1.2 -1.3 -0.7
Trunk fat-free mass 2.0 11.5 19.9 -3.5 4.2 4.5 0.8 4.3 -0.5 2.7 4.0
Hip circumference 0.1 0.6 1.2 -0.7 0.8 1.1 -1.1 0.7 -0.8 -0.1 0.4
Time employed in main current job 0.3 0.3 1.6 0.3 0.4 0.4 1.3 -0.2 -0.1 -0.6 -0.3
Alcohol intake versus 10 years previously 0.2 0.3 0.7 0.6 -0.5 -0.6 -0.1 -0.8 0.3 -0.5 -0.6
Father’s age at death 0.1 0.1 0.3 -0.4 -0.1 -0.0 -0.6 0.0 -0.1 -0.1 -0.1
Worrier / anxious feelings 0.3 0.5 1.6 0.2 -0.0 -0.2 1.2 -0.3 1.2 1.1 0.3
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.2 5.3 -0.5 1.0 0.8 0.4 1.6 2.3 2.2 1.6
Falls in the last year 0.3 0.4 1.0 0.5 -0.8 -0.6 -0.4 -0.2 -1.0 0.9 0.6
Hair/balding pattern: Pattern 3 0.5 0.7 1.4 -1.0 1.0 0.9 -0.4 0.5 -1.2 -1.2 -0.3
Number of live births 0.7 1.0 1.7 1.0 -1.1 -1.2 0.0 -1.3 0.3 -1.0 -1.1
Forced expiratory volume in 1-second (FEV1) 3.2 10.7 16.8 -1.4 2.7 2.8 3.8 3.4 3.3 4.1 3.9
Pulse rate 0.6 1.0 2.2 0.4 -0.9 -0.8 -1.5 -1.0 -0.4 -1.5 -1.0
Happiness 1.8 2.2 3.9 1.3 -2.0 -1.9 -1.6 -1.8 -0.8 0.1 -1.2
Noisy workplace 0.8 1.0 6.1 -0.6 0.4 0.6 0.3 0.0 -2.5 0.2 0.8
Qualifications: A levels/AS levels or equivalent 0.2 0.5 2.3 -0.6 0.3 0.2 -0.1 1.0 1.5 0.4 0.4
Serious illness, injury or assault of a close relative in last 2 years 2.1 2.4 4.6 1.1 -1.6 -1.7 -0.8 -2.1 0.3 -1.7 -2.1
Mouth/teeth dental problems: Dentures 0.7 1.2 7.2 0.8 -0.5 -0.5 0.4 -1.0 -2.7 -0.5 -0.3
Asthma 0.6 1.2 2.4 -0.5 0.9 0.8 0.5 1.1 -1.5 1.3 1.5
Medication: Ibuprofen (e.g. Nurofen) 1.2 1.5 3.6 -0.7 1.1 1.2 1.9 0.7 0.8 1.4 1.6
Medication: Cholesterol lowering 1.6 2.4 8.7 -0.0 -0.1 -0.4 -2.8 -0.1 -3.0 -1.5 -0.7
Depression (self-reported) 0.8 0.9 1.8 1.2 -1.3 -1.3 -0.8 -1.2 0.4 0.4 -0.3
Medication: Lansoprazole 0.2 0.3 1.0 0.4 -0.2 -0.2 -0.2 -0.6 0.4 -0.4 -1.0
Prospective memory result 0.6 0.8 2.1 1.1 -0.6 -0.5 0.9 -0.7 -0.9 1.4 0.3
Lung cancer (father) 0.7 0.9 3.8 0.4 -1.0 -0.8 -1.9 -0.4 -1.0 0.1 -0.4
Illnesses of mother 1.1 1.3 2.4 -0.7 1.1 1.0 1.0 1.3 -0.9 1.4 1.6
Forced expiratory volume in 1-second (FEV1), Best measure 2.6 8.3 13.0 -1.5 2.6 2.5 3.0 3.0 3.6 3.2 3.1
Pulse wave Arterial Stiffness index 0.4 0.5 1.3 0.8 -0.3 -0.4 1.1 -0.9 -0.4 -0.8 -0.3
Impedance of arm (left) 0.4 1.7 3.5 0.4 -1.8 -1.7 -1.9 -0.4 1.5 0.9 -0.6
Arm fat mass (right) 0.1 0.6 1.7 -0.7 0.3 0.7 -1.1 0.1 -1.3 -0.8 -0.0
Trunk predicted mass 2.0 11.5 20.1 -3.5 4.2 4.5 0.7 4.3 -0.5 2.7 3.9
Standing height 2.3 22.5 40.0 -4.9 4.8 5.2 -0.5 6.3 0.7 5.6 5.7
Length of working week for main job 0.6 0.7 1.6 -1.0 0.9 0.9 -0.5 0.5 0.4 -1.3 -0.7
Exposure to tobacco smoke at home 3.2 3.6 7.0 1.7 -2.4 -2.2 -1.3 -2.6 -1.0 -1.5 -1.9
Breastfed as a baby 0.9 1.1 2.2 -1.1 1.5 1.3 1.2 1.1 0.3 0.6 0.7
Tense / ‘highly strung’ 1.2 2.0 4.2 1.7 -1.4 -1.6 1.0 -1.7 2.0 0.7 -0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 2.3 3.5 7.1 2.3 -2.7 -2.6 -1.2 -2.2 -1.4 0.8 -0.4
Hair/balding pattern: Pattern 4 0.0 0.1 0.3 -0.1 0.4 0.3 0.4 -0.1 0.5 -0.1 -0.1
Birth weight of first child 1.0 1.8 3.2 -1.3 1.4 1.5 0.0 1.5 -0.8 1.8 1.6
Peak expiratory flow (PEF) 3.6 8.4 14.0 -0.7 2.4 2.5 3.5 2.9 2.7 3.7 3.6
Pulse wave reflection index 1.1 1.4 5.9 1.0 0.2 0.0 2.4 0.4 0.5 1.4 1.4
Ever highly irritable/argumentative for 2 days 0.4 0.4 1.3 0.6 -0.6 -0.5 -0.9 -0.0 -1.1 0.6 0.4
Loud music exposure frequency 2.1 2.3 9.0 -1.6 1.2 1.1 -3.0 1.3 0.9 -1.2 -0.7
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.1 -1.0 0.5 0.5 -0.8 1.0 0.6 0.3 0.5
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 1.1 -0.1 0.4 0.3 0.9 0.4 0.4 1.1 0.6
Blood clot in the leg (DVT) 0.8 1.1 6.2 -0.5 0.0 0.2 -0.8 -0.4 -2.5 -1.2 -0.4
Medication: Paracetamol 0.6 1.0 3.2 0.2 0.3 0.4 1.8 -0.0 -0.8 1.5 1.3
Headache pain in last month 0.6 1.0 2.2 1.4 -1.1 -1.1 0.6 -0.7 1.5 0.8 0.0
Medication for cholesterol, blood pressure or diabetes 1.2 2.0 7.6 0.2 0.1 0.1 2.5 0.1 2.8 1.2 0.4
Glaucoma (self-reported) 0.4 0.5 3.1 0.4 -0.3 -0.4 -0.3 0.4 1.8 0.6 0.2
Gout (self-reported) 1.6 2.2 4.2 -1.9 2.0 2.0 -0.4 2.0 -0.1 -0.0 1.3
Hypothyroidism/myxoedema (self-reported) 0.2 0.4 1.0 -1.0 0.5 0.7 -0.4 -0.2 -0.0 -0.8 -1.0
Medication: Amlodipine 0.1 0.2 0.6 -0.0 0.0 -0.0 -0.8 0.2 -0.7 -0.3 -0.1
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.9 0.4 0.1 0.1 0.8 0.1 -1.4 0.5 0.6
Birth weight 0.8 1.8 5.5 -1.4 0.6 0.8 -2.3 1.4 -1.7 0.6 0.7
Chronic bronchitis/emphysema (mother) 0.4 0.5 1.4 0.8 -1.2 -1.1 0.1 -0.7 0.0 0.6 -0.1
High blood pressure (siblings) 0.6 0.8 1.9 -1.1 1.0 1.2 -0.7 0.7 -1.4 -0.4 0.2
Forced vital capacity (FVC), Best measure 2.1 7.8 13.3 -1.1 2.2 2.1 2.9 2.9 3.7 3.4 3.1
Body fat percentage 0.3 1.3 4.8 0.2 -0.8 -0.4 -1.5 -0.9 -2.2 -1.0 -0.6
Leg fat percentage (right) 0.5 1.8 4.7 1.3 -1.2 -1.0 -0.1 -1.8 -2.2 -1.2 -0.8
Arm fat-free mass (right) 1.4 7.2 12.3 -2.4 3.3 3.5 1.0 3.2 -1.2 2.3 3.3
Exposure to tobacco smoke outside home 0.6 0.8 2.0 1.4 -1.3 -1.2 -0.1 -0.4 -0.1 1.0 0.3
Comparative body size at age 10 0.4 1.2 2.9 1.5 -1.0 -1.1 0.9 -1.0 1.7 0.3 -0.3
Number of full brothers 1.6 2.0 6.7 1.1 -0.3 -0.2 1.7 0.9 -0.0 2.6 2.2
Worry too long after embarrassment 0.7 1.1 3.1 1.1 -0.9 -1.0 -0.5 -0.1 1.7 1.6 0.5
Seen a psychiatrist for nerves, anxiety, tension or depression 0.7 0.9 3.6 0.5 -1.0 -0.8 -1.0 -0.7 -0.3 1.9 0.5
Wheeze or whistling in the chest in last year 0.4 0.7 3.6 -0.6 0.3 0.5 -0.4 0.3 -1.9 0.6 0.5
Number of children fathered 1.2 1.3 3.1 -0.3 1.2 1.4 1.8 0.9 0.2 1.1 1.3
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 1.7 0.7 -0.7 -0.6 -0.2 -1.3 -1.3 0.0 -0.8
Age at first live birth 1.3 2.2 5.7 -1.6 1.5 1.5 0.3 2.4 0.9 1.3 1.6
Pulse wave peak to peak time 0.7 0.8 1.4 -1.0 0.5 0.7 -1.1 1.1 0.3 1.2 0.7
Health satisfaction 0.5 0.7 4.5 -0.5 0.0 -0.1 -2.1 -0.1 -0.4 -0.7 -0.6
Shortness of breath walking on level ground 0.2 0.3 0.7 -0.7 0.8 0.9 0.2 0.4 -0.1 -0.2 0.2
Qualifications: College or University degree 0.6 1.8 4.7 2.0 -1.4 -1.6 0.5 -0.7 2.2 0.9 -0.2
Eye problems/disorders: None of the above 1.1 1.2 3.0 1.7 -1.5 -1.4 0.6 -1.5 0.2 0.3 -0.3
Mouth/teeth dental problems: Loose teeth 1.2 1.4 3.4 -0.0 0.2 0.1 1.3 0.9 -1.9 1.4 1.8
Emphysema/chronic bronchitis 2.1 2.3 5.8 -2.2 2.3 2.4 0.8 1.3 0.1 0.0 0.5
Medication for pain relief, constipation, heartburn 0.3 0.5 1.4 -1.2 0.6 0.8 -0.7 0.9 -0.7 -0.5 0.1
Neck or shoulder pain in last month 0.2 0.3 1.7 0.4 -0.0 -0.2 0.6 -0.3 -1.3 -0.3 0.1
Medication: Blood pressure 0.6 1.1 4.1 -0.2 -0.1 -0.1 -2.0 -0.2 -2.0 -0.8 -0.3
Angina (self-reported) 1.2 1.6 3.6 -1.9 1.0 1.2 -1.9 0.5 -1.7 -0.3 -0.3
Migraine (self-reported) 0.6 0.7 2.4 -0.8 0.2 0.3 -1.6 0.3 -1.2 0.7 0.8
Medication: Ibuprofen 1.4 1.7 3.3 -1.1 1.3 1.4 1.6 0.9 0.0 1.4 1.8
Medication: Allopurinol 0.9 1.2 2.0 -1.0 1.1 1.3 -0.4 1.3 -1.4 0.1 1.2
Medication: Omeprazole 1.4 1.7 4.9 0.3 -0.6 -0.7 -2.2 -0.8 0.6 -1.7 -1.9
Medication: Seretide 50 evohaler 1.3 1.5 6.2 1.0 0.1 -0.1 2.5 0.7 0.1 1.3 1.5
Mean time to correctly identify matches 2.9 5.5 14.2 0.0 -1.7 -1.5 -3.8 -1.9 -2.3 -2.8 -2.8
Heart disease (mother) 1.2 1.5 4.2 0.4 -0.8 -0.7 -1.6 -1.0 -0.1 -2.1 -1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.5 1.7 7.7 0.0 1.0 1.1 2.8 0.4 -0.6 1.1 1.4
Whole body fat mass 0.2 0.9 4.2 -0.8 0.5 0.9 -1.1 0.4 -2.1 0.0 0.6
Leg fat mass (right) 0.1 0.5 3.6 0.1 0.1 0.4 0.0 -0.3 -1.9 -0.0 0.5
Arm predicted mass (right) 1.6 8.3 14.3 -2.8 3.5 3.8 0.8 3.5 -1.2 2.4 3.5
Pulse rate, automated reading 0.7 2.3 11.0 -0.5 0.6 0.5 -0.9 -0.2 -3.3 -2.3 -0.6
Alcohol intake frequency. 0.3 0.8 1.4 -0.6 0.9 0.9 0.3 1.2 0.6 1.0 1.1
Comparative height size at age 10 0.7 4.0 8.5 -1.6 1.6 1.8 -0.8 2.9 0.6 2.6 2.7
Number of full sisters 0.7 0.9 2.9 0.8 -0.3 -0.2 1.6 -0.3 1.7 0.8 0.2
Suffer from ‘nerves’ 0.3 0.5 1.4 0.1 -0.5 -0.6 -0.9 -1.0 0.5 -0.6 -1.2
Overall health rating 0.4 0.8 2.1 -0.7 0.2 0.2 -1.5 -0.5 -0.1 -1.4 -1.2
Chest pain or discomfort 0.4 0.6 1.3 -1.1 0.7 0.5 -0.7 0.3 -0.3 -1.1 -0.9
Had major operations 0.2 0.2 1.4 0.2 0.0 0.1 0.2 0.2 0.1 1.2 0.5
Age at last live birth 0.9 1.3 5.2 -0.6 0.6 0.7 0.9 1.4 2.3 0.8 0.8
Family relationship satisfaction 0.6 0.8 2.0 0.6 -0.8 -0.8 -0.9 -1.2 -0.2 -0.5 -1.4
Leg pain on walking 0.2 0.2 1.6 0.2 0.2 0.1 -0.0 0.2 -1.3 0.0 0.2
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 2.4 0.7 -0.9 -1.1 -1.6 -0.5 0.4 -0.1 -0.7
Commuting to job workplace: Car/motor vehicle 2.0 2.3 7.7 0.7 -0.1 -0.0 1.9 0.7 -0.4 2.8 2.5
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 2.0 -0.8 1.3 1.2 -0.2 1.4 0.9 -0.3 0.4
Medication: Aspirin 0.5 0.7 2.3 0.5 -0.6 -0.7 -0.8 -0.9 0.1 -0.9 -1.5
Supplements: Vitamin C 0.6 0.7 1.3 0.4 -0.9 -1.1 -0.7 -0.6 1.0 -0.9 -1.0
Knee pain experienced in last month 0.2 0.3 1.2 0.0 -0.0 0.2 0.2 -0.3 -1.1 0.8 0.5
Hypertension (Self-reported) 0.3 0.9 4.2 0.4 -0.2 -0.2 -0.7 -0.6 -2.0 -1.3 -0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.6 3.1 5.4 2.3 -1.9 -2.1 -0.2 -2.2 0.7 -1.0 -2.1
Illnesses of father: Heart disease 1.2 1.6 3.1 -0.9 1.6 1.5 1.8 1.2 0.4 0.6 1.3
Illnesses of siblings: Diabetes 0.6 0.7 2.2 -0.3 0.4 0.2 -1.2 0.0 -1.1 -1.5 -0.5
Smoking status: Previous 0.2 0.3 1.3 -0.5 -0.2 0.0 -1.1 -0.2 -0.6 0.2 -0.2
Forced expiratory volume in 1-second (FEV1), predicted 4.6 9.6 17.8 -2.8 3.4 3.4 1.2 4.2 1.1 3.3 3.8
Whole body fat-free mass 1.9 10.7 18.7 -3.4 4.0 4.3 0.5 4.2 -0.6 2.6 3.8
Leg fat-free mass (right) 1.8 9.7 17.0 -3.4 3.8 4.1 -0.0 4.1 -0.3 2.4 3.4
Arm fat percentage (left) 0.3 1.0 2.7 0.0 -0.7 -0.4 -1.6 -0.8 -1.5 -1.2 -0.8
Average weekly red wine intake 0.2 0.2 0.7 -0.0 0.5 0.4 0.8 0.3 0.5 0.4 0.5
Handedness (chirality/laterality): Left-handed 1.1 1.3 2.9 -0.9 1.7 1.3 0.9 1.7 -0.2 -0.2 1.1
Mood swings 1.5 2.8 12.9 1.5 -1.2 -1.1 1.0 -0.6 0.2 3.6 1.7
Loneliness, isolation 0.5 0.8 1.5 -1.1 0.8 1.0 0.8 0.2 -0.7 1.2 0.9
Long-standing illness, disability or infirmity 0.9 1.4 3.8 -1.1 0.7 0.6 -1.9 0.0 -2.0 -1.0 -0.7
Ever had bowel cancer screening 3.5 4.1 6.7 1.2 -2.0 -2.0 -1.8 -2.6 -1.7 -2.1 -2.4
Diabetes diagnosed by doctor 0.7 1.2 4.9 -1.0 0.7 0.8 -0.8 0.0 -2.2 -1.2 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 3.7 -0.2 0.2 0.1 -0.1 0.5 1.9 0.3 0.2
Friendships satisfaction 0.9 1.1 2.6 1.0 -1.2 -1.3 -0.8 -1.6 0.4 -0.1 -1.2
Qualifications: nursing, teaching 1.6 2.5 7.2 2.7 -2.2 -2.3 -0.4 -0.6 0.7 1.1 0.4
Commuting to job workplace: Walk 1.5 1.7 4.7 -1.6 0.8 0.9 -2.2 0.3 -0.8 -1.7 -1.0
Eye problems/disorders: Cataract 0.8 1.0 2.3 -1.5 1.2 1.2 -0.5 0.6 -1.0 -0.8 -0.1
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 1.6 0.6 -0.5 -0.8 -1.3 -0.0 0.4 -0.8 -0.8
Medication for cholesterol 0.7 1.1 3.0 1.7 -1.4 -1.3 -0.2 -0.4 1.1 0.9 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.5 2.9 5.6 2.4 -2.1 -2.1 0.4 -2.3 0.9 -0.5 -1.5
Back pain experienced in last month 0.3 0.4 1.1 0.1 -0.0 -0.1 -1.0 -0.5 -0.4 -0.9 -1.1
Mineral and other dietary supplements 1.3 1.7 4.1 -1.4 0.8 1.0 -1.4 1.7 -2.0 -0.1 1.1
Breast cancer (self-reported) 0.4 0.5 2.5 0.6 -0.4 -0.5 -1.6 0.0 0.1 -0.4 -0.6
Asthma (self-reported) 0.4 0.8 2.6 -0.3 0.8 0.7 0.4 0.8 -1.6 0.8 1.2
Osteoporosis (self-reported) 2.3 2.8 6.1 1.7 -2.0 -2.0 0.0 -2.5 -0.1 -1.2 -2.0
Osteoarthritis (self-reported) 1.0 1.2 2.2 -1.4 1.3 1.4 -1.5 1.0 -1.0 -0.2 0.3
Medication: Aspirin 0.8 1.0 2.7 0.9 -0.9 -1.1 -0.7 -1.3 0.1 -0.9 -1.7
Medication: Gliclazide 1.0 1.1 1.6 0.5 -1.0 -1.0 -1.2 -1.1 -1.3 -1.2 -1.0
Illnesses of father: None of the above (group 1) 0.6 0.8 4.8 -0.3 -0.4 -0.4 -2.2 -0.2 -0.7 -0.5 -0.5
Smoking status: Current 0.4 0.7 4.1 -0.2 -0.1 -0.1 -1.1 -0.0 -2.0 -0.3 -0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.0 4.4 0.1 0.4 0.5 2.1 -0.1 1.4 1.0 0.7
Whole body water mass 1.8 10.5 18.7 -3.4 4.0 4.3 0.4 4.2 -0.5 2.5 3.7
Leg predicted mass (right) 1.8 9.5 16.6 -3.4 3.8 4.1 -0.1 4.1 -0.2 2.4 3.3
Arm fat mass (left) 0.1 0.6 2.2 -0.5 0.2 0.5 -1.1 -0.0 -1.5 -0.7 -0.1
Number of self-reported non-cancer illnesses 0.5 0.9 2.8 -1.0 0.8 0.6 -1.5 0.5 -1.7 -0.3 0.2
Average weekly champagne plus white wine intake 0.3 0.4 1.5 -0.3 0.5 0.3 -0.6 0.3 1.2 -0.8 -0.6
Miserableness 0.9 1.6 7.3 0.3 -0.2 -0.3 1.1 0.3 1.6 2.7 1.3
Guilty feelings 0.5 0.8 3.8 0.1 -0.3 -0.3 -0.8 0.6 0.2 1.9 1.3
Wears glasses or contact lenses 0.4 0.4 0.9 0.8 -0.8 -0.7 0.2 0.3 0.2 0.9 0.7
Ever taken oral contraceptive pill 1.1 1.2 4.3 -0.1 0.2 0.3 0.1 1.1 -0.6 2.1 1.9
Hearing aid user 1.6 1.8 3.4 -1.7 1.8 1.8 -0.7 1.7 -1.1 -0.8 0.2
Mother’s age at death 0.7 0.8 1.5 0.3 -0.8 -0.8 -1.2 -0.7 0.7 -1.2 -1.2
Financial situation satisfaction 0.9 1.1 2.1 0.7 -1.2 -1.2 -1.0 -1.5 0.9 0.0 -1.1
Tinnitus: Yes, now most or all of the time 1.6 1.9 4.2 2.0 -1.7 -1.7 0.6 -1.9 0.1 -0.4 -1.2
Commuting to job workplace: Public transport 1.4 1.7 7.1 -0.2 -0.0 -0.2 -0.6 -0.9 -0.3 -2.7 -2.3
Eye problems/disorders: Glaucoma 0.7 0.8 1.9 -0.4 0.6 0.4 -0.3 1.3 1.4 1.1 1.0
Medication: Blood pressure 0.7 1.4 4.3 -1.2 1.5 1.3 0.2 0.5 -2.1 -1.1 -0.1
Pain type(s) experienced in last month: Hip pain 0.6 0.8 1.9 1.4 -1.0 -1.0 0.3 -0.4 -0.6 1.2 0.5
Supplements: Fish oil (including cod liver oil) 0.7 1.0 3.2 1.1 -0.3 -0.4 1.4 -0.8 1.8 0.1 -0.5
High cholesterol (Self-reported) 0.2 0.3 1.6 0.0 0.0 0.0 -0.7 0.4 -1.3 0.4 0.6
Medication: Bendroflumethiazide 0.2 0.3 1.2 -0.1 0.5 0.5 -0.3 0.3 -1.1 0.1 0.3
Medication: Paracetamol 0.6 0.9 2.3 -0.3 0.6 0.6 0.7 0.4 -1.5 1.2 1.3
Medication: Lisinopril 0.3 0.4 1.1 0.5 -0.7 -0.7 -0.7 -0.6 -1.1 0.2 -0.2
Medication: Atorvastatin 1.4 1.7 6.1 -1.6 0.8 0.8 -2.5 0.7 -1.5 -1.0 -0.6
Illnesses of father: High blood pressure 0.2 0.2 0.9 0.1 -0.4 -0.3 -0.3 -0.3 -0.9 -0.5 -0.4
Alcohol drinker status: Never 0.8 0.9 1.8 -1.2 1.2 1.3 0.2 1.2 0.4 -0.0 0.8
Ever smoked 0.5 0.9 5.2 0.0 -0.9 -0.8 -2.3 -0.1 -0.4 -0.1 -0.4
Basal metabolic rate 1.5 8.6 15.2 -3.1 3.6 3.9 0.2 3.8 -0.6 2.3 3.4
Leg fat percentage (left) 0.5 1.8 6.7 1.0 -1.0 -0.8 -0.4 -1.6 -2.6 -1.2 -0.7
Arm fat-free mass (left) 1.0 5.0 9.2 -2.1 2.8 3.0 0.4 2.7 -0.9 1.7 2.7
Number of operations (self-reported) 0.2 0.3 1.7 -0.4 0.5 0.6 -0.1 0.1 -1.3 0.2 0.4
Average weekly beer plus cider intake 0.2 0.3 0.7 -0.0 0.1 0.3 0.9 -0.8 -0.2 -0.6 -0.7
Irritability 0.5 0.9 2.9 0.6 -0.8 -0.8 -0.1 -0.3 1.7 1.7 0.3
Risk taking 3.1 4.5 9.2 3.0 -2.7 -2.7 1.1 -3.0 -0.0 -0.2 -1.2
Ever had prostate specific antigen (PSA) test 0.5 0.6 1.0 1.0 -1.0 -0.9 -0.6 -1.0 -0.4 -0.5 -0.7
Fractured/broken bones in last 5 years 0.2 0.3 0.6 0.5 -0.7 -0.6 -0.6 0.1 0.8 0.7 0.3
Age started oral contraceptive pill 1.2 1.5 4.9 -0.9 1.3 1.3 1.6 0.2 -2.2 -0.1 0.7
Diastolic blood pressure, automated reading 0.8 2.4 5.6 2.4 -2.0 -2.0 0.9 -1.7 0.6 -0.3 -1.1
Ever depressed for a whole week 1.2 1.5 6.6 0.2 -0.5 -0.6 -1.9 0.4 -2.6 0.3 0.9
Unable to work because of sickness or disability 0.5 0.6 1.1 -0.7 0.9 1.1 -0.4 0.3 -1.0 0.9 0.6
Commuting to job workplace: Cycle 0.8 0.9 2.9 -0.1 -0.2 -0.1 -0.6 -0.9 -1.2 -1.7 -1.4
Myopia 0.8 1.2 5.1 0.5 -0.6 -0.6 -0.8 0.6 -0.0 2.3 1.5
Vascular/heart problems diagnosed by doctor 0.3 0.7 3.9 -0.1 0.1 0.0 0.8 0.3 2.0 0.8 0.4
Cholesterol lowering medication 0.4 0.6 1.6 -1.3 0.9 0.9 -0.3 0.4 0.5 -0.9 -0.7
Medication: Omeprazole (e.g. Zanprol) 2.1 2.5 7.8 0.8 -1.2 -1.4 -2.8 -0.9 0.3 -1.8 -2.0
Pain experienced in last month 1.0 1.6 4.7 -0.5 -0.8 -0.7 -1.9 -0.4 0.6 -2.2 -1.7
Supplements: Calcium 0.5 0.6 1.3 -1.0 0.5 0.4 -0.7 -0.3 0.7 -1.1 -1.1
Basal cell carcinoma (self-reported) 0.3 0.3 0.7 0.4 -0.6 -0.4 0.2 -0.8 -0.4 -0.5 -0.9
Heart attack/myocardial infarction (self-reported) 0.4 0.5 0.9 -0.9 0.5 0.4 -1.0 -0.2 -0.5 -0.9 -1.0
Deep venous thrombosis (DVT) (self-reported) 0.7 1.0 6.3 -0.3 -0.1 0.1 -0.6 -0.3 -2.5 -0.9 -0.2
Heart disease (siblings) 0.7 0.9 3.6 -0.4 -0.7 -0.6 -1.9 -0.4 -1.0 -1.1 -0.6
Alcohol drinker status: Previous 1.9 2.2 6.4 -0.1 1.2 1.0 1.5 1.4 -0.2 2.5 2.1
Pack years of smoking 1.9 2.8 7.7 -0.7 -0.2 -0.2 -1.7 -1.2 -2.8 -2.5 -1.9
Impedance of whole body 0.4 1.9 4.7 1.3 -2.2 -2.2 -1.1 -1.0 0.9 1.0 -0.5
Leg fat mass (left) 0.2 0.7 4.4 -0.2 0.3 0.6 -0.1 -0.1 -2.1 -0.1 0.6
Arm predicted mass (left) 1.0 5.2 9.9 -2.2 2.9 3.1 0.3 2.7 -1.0 1.6 2.6