Hub : Genes

TIAM2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Thyroid	0.1570	0.0550	0.00320	0.002	NA	0.032	NA	0.024	2.3e-01	NA	1.5e-03	NA	6.0e-03
2	GTEx	Whole Blood	0.1350	0.0450	0.00170	0.053	NA	0.039	NA	0.032	1.2e-05	NA	1.4e-04	NA	6.2e-04
3	NTR	Blood	0.2450	0.0305	0.00000	0.089	0.121	0.128	0.028	0.129	3.5e-27	5.5e-37	3.1e-39	1.9e-09	2.1e-39
4	ROSMAP	Brain Pre-frontal Cortex	0.0769	0.0243	0.00011	0.016	0.021	0.020	0.020	0.020	3.6e-03	7.6e-04	1.1e-03	1.2e-03	1.2e-03
5	YFS	Blood	0.6148	0.0244	0.00000	0.335	0.540	0.570	0.546	0.566	6.5e-114	2.9e-215	9.4e-234	1.5e-218	6.7e-231
6	TCGA	Breast Invasive Carcinoma	0.0378	0.0144	0.00270	0.016	0.008	0.005	NA	0.010	2.6e-04	6.1e-03	2.5e-02	NA	2.7e-03
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0470	0.0219	0.00900	0.006	0.015	0.005	NA	0.006	5.9e-02	7.3e-03	7.5e-02	NA	6.1e-02
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1320	0.0470	0.00034	0.076	0.069	0.026	NA	0.055	3.7e-05	8.5e-05	1.2e-02	NA	4.2e-04
9	TCGA	Pheochromocytoma and Paraganglioma	0.1300	0.0580	0.00880	0.012	0.025	0.004	NA	0.024	1.0e-01	3.4e-02	2.1e-01	NA	3.8e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.1	1.7	5.7	-0.7	0.5	0.9	1.2	-0.1	-1.4	0.5	2.4	2.1
Bipolar Disorder or Schizophrenia	0.9	2.2	7.1	0.6	0.6	0.5	1.1	-0.3	-1.8	1.4	2.2	2.7
Depressed Affect (Nagel 2018)	0.5	1.1	5.6	1.1	-0.5	0.1	2.4	-0.0	0.5	1.0	-0.5	1.2
Depression (Nagel 2018)	0.9	1.4	8.4	0.7	-0.2	0.2	2.9	-0.1	-0.2	1.6	-0.2	1.0
Intelligence (Savage-Jansen 2018)	1.7	5.3	14.2	0.3	-1.8	-1.6	-1.5	-1.5	-2.6	-3.8	-3.0	-2.7
Neuroticism (Nagel 2018)	0.3	0.8	1.6	0.4	-0.4	-1.3	1.2	-0.8	0.7	-0.9	-1.3	0.0
Schizophrenia (2018)	0.5	1.0	3.0	1.4	0.2	-0.2	0.3	-0.3	-1.1	1.4	0.9	1.7
Schizophrenia vs Biploar Disorder	0.2	0.3	0.7	0.1	-0.5	-0.7	-0.4	-0.9	0.5	0.1	-0.8	0.6
Worry (Nagel 2018)	0.8	1.8	8.0	0.3	-0.2	-2.8	0.0	-1.9	0.3	-1.9	-0.5	-0.7
Alzheimer’s Disease (in mother)	0.9	1.0	5.0	0.1	2.2	-0.6	-1.6	0.3	1.0	0.0	-0.7	-0.0
Alzheimer’s Disease (in father)	0.9	1.0	3.2	-0.1	-1.8	-0.4	-1.5	-0.2	0.7	-1.1	-1.2	0.0
Alzheimer’s Disease (including proxy)	0.5	0.7	3.3	-0.9	0.7	-0.4	-1.8	-0.1	0.8	0.6	-0.1	0.7
Crohns Disease (2017)	0.3	0.8	4.1	-0.2	-2.0	0.1	0.2	-0.7	0.4	1.0	-0.3	1.0
Irritable Bowel Disease (IBD)	0.2	0.5	1.2	-0.0	-0.8	1.0	-1.1	0.4	-0.7	-0.4	-0.9	-0.5
Ulcerative Colitis (UC)	0.9	1.8	4.0	-0.3	0.3	1.3	-1.9	1.1	-0.9	-1.5	-1.5	-2.0
Major Depression (MDD)	0.7	0.9	2.8	0.6	-0.9	0.7	1.7	0.1	0.1	1.4	0.5	1.0
Reaction Time	0.7	1.3	3.5	0.4	-0.9	-0.9	1.9	-1.1	1.1	1.2	-0.4	1.7
Verbal and Numeric Reasoning (VNR)	2.0	4.9	12.6	-0.9	-1.8	-1.0	-1.6	-1.4	-2.4	-3.6	-2.9	-2.8
Breast Cancer	0.5	1.2	3.6	-0.6	1.6	0.7	0.8	0.5	0.2	0.5	1.6	1.9
Ovarian Cancer	0.6	0.7	2.0	-1.4	-0.9	0.1	-1.1	0.7	0.7	-1.0	0.7	-0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.3	0.5	2.1	-0.5	1.5	0.5	-1.0	0.4	0.7	0.1	0.0	-0.3
Bipolar Disorder (2011)	0.5	0.4	3.0	-0.8	0.1	0.3	0.1	0.4	0.0	0.0	1.7	0.0
Body Mass Index (BMI) (2010)	0.5	0.7	4.0	-0.2	0.5	0.8	0.4	0.8	-2.0	-0.3	0.5	0.3
Coronary Artery Disease (CAD)	1.9	2.3	6.4	-0.7	-2.0	-0.2	2.5	-1.0	-1.8	2.2	0.7	0.5
Crohns Disease (2012)	0.5	0.9	1.8	-0.7	-1.2	-0.1	1.1	-0.9	-0.3	1.0	1.0	1.4
Mean Putamen Volume	0.5	0.6	1.6	-0.5	-0.6	-0.5	0.7	-0.7	-0.8	1.1	-0.4	1.3
Fasting Glucose	0.5	0.6	1.8	-1.1	0.4	-0.8	-0.2	-0.9	-0.6	-1.3	-0.2	-0.1
HbA1C	0.6	0.6	2.2	-0.3	-1.2	-1.0	0.3	-0.5	-0.4	1.5	0.4	-0.4
HDL Cholesterol	0.4	0.6	2.0	0.8	-0.0	0.6	-0.2	1.1	1.4	1.0	0.6	0.3
LDL Cholesterol	0.7	1.1	3.5	-0.9	1.0	-0.8	1.0	-0.7	0.0	0.5	1.9	1.3
Lupus	0.3	0.4	2.0	-1.4	0.9	-0.2	-0.6	-0.0	-0.7	-0.2	-0.3	-0.4
Neuroticism (2016)	0.2	0.2	0.5	0.5	0.4	-0.3	0.7	-0.4	-0.4	0.6	0.0	0.7
Primary Biliary Cirrhosis	0.8	1.1	3.6	0.3	0.1	1.2	-0.4	0.9	-1.2	-1.5	-0.3	-1.9
Rheumatoid Arthritis	0.5	0.7	4.2	0.3	2.0	-0.0	-0.1	0.4	-1.0	-0.3	-0.3	0.6
Schizophrenia (2014)	0.6	1.3	3.8	1.2	1.1	-0.1	0.2	-0.4	-0.7	1.1	1.9	1.9
Triglycerides	0.1	0.1	0.4	-0.5	0.6	-0.1	0.1	-0.2	0.7	-0.3	-0.4	-0.2
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.0	1.1	0.6	0.1	-1.4	0.5	-0.3	-1.1	-0.9	-0.3
Ulcerative Colitis	0.8	1.2	3.3	-0.7	-0.2	1.2	-1.0	0.8	-1.8	-0.9	-0.3	-1.8
Blood Eosinophil Count	0.2	1.2	7.8	-1.2	1.0	-0.1	0.0	0.3	-0.6	-2.8	-0.3	-0.5
Blood Platelet Count	0.2	2.0	5.2	-0.9	1.9	0.8	2.1	1.0	-0.4	2.3	1.3	0.9
Blood Red Count	0.1	1.1	2.9	-1.1	0.1	1.6	1.2	1.2	-1.7	0.7	0.2	0.4
Blood White Count	0.3	2.4	7.5	-1.1	1.5	1.6	1.5	1.4	1.1	0.2	2.7	1.7
Heel T-Score	0.7	5.2	31.4	0.5	-0.6	0.1	2.8	-0.1	-5.6	-0.7	1.9	-1.8
BMI	0.7	4.0	9.6	-2.5	-1.1	2.1	3.1	1.7	-0.4	2.2	2.0	1.6
Height	1.3	25.9	72.6	2.2	0.0	-3.0	-4.6	-0.2	1.2	-8.5	-8.0	-7.7
Waist Hip Ratio (WHR)	0.1	0.6	1.9	0.2	-0.9	0.5	0.9	0.2	0.8	-0.6	0.6	1.4
Systolic Blood Pressure	1.1	5.4	15.1	1.3	0.1	0.6	-3.9	1.4	2.7	-2.1	-2.9	-3.1
Smoking Status	0.4	1.0	3.6	0.2	0.7	0.1	1.9	0.3	-0.6	0.3	1.6	1.3
Allergy or Eczema	0.3	0.7	2.2	-1.1	-0.3	-1.5	0.0	-1.4	-0.1	0.8	0.6	0.6
Cardiovascular Disease	0.2	0.6	1.7	0.2	0.7	0.8	-1.2	1.3	0.8	-0.3	-0.5	-0.0
Hypothyroidism (self reported)	0.9	2.2	6.7	0.9	1.7	1.2	0.6	1.4	-1.8	0.2	2.6	1.4
Respiratory disease	0.4	0.8	1.9	-0.0	0.9	-1.4	1.0	-1.2	-0.6	0.6	-0.5	1.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.4	-0.7	-1.2	0.9	0.2	0.9	0.2	0.3	0.5	0.1
Lung FEV1/FVC ratio	0.4	1.9	5.2	0.8	-2.3	1.1	1.4	-0.4	-0.0	2.0	0.9	1.8
Lung FVC	2.4	12.1	40.8	0.6	-1.7	1.6	6.4	-1.1	0.2	5.2	3.3	4.8
Neuroticism	0.4	1.0	2.5	0.7	0.5	-1.6	0.8	-0.3	1.1	-1.1	-1.4	-0.8
Chronotype (morning person)	0.2	0.5	2.9	0.0	-0.1	0.3	-0.2	0.6	-1.7	-0.3	1.0	-0.5
Hair Pigment	0.0	1.1	2.9	-0.4	-1.1	-0.7	0.3	-0.3	0.6	1.4	-1.6	-1.7
Tanning	0.1	0.8	4.2	0.6	0.5	-0.8	-0.7	-0.7	2.0	-0.6	-0.1	0.2
Hand grip strength (left)	1.5	3.9	15.3	-0.7	-1.6	-1.0	-0.4	-0.7	0.3	-3.9	-2.7	-2.7
Number of treatments/medications taken	0.7	1.2	6.2	0.9	1.3	-0.5	-0.8	0.5	2.5	-0.2	-0.8	0.4
Average weekly spirits intake	0.8	0.9	2.4	-1.2	-0.5	-0.7	1.5	-1.2	-0.5	1.3	0.6	0.6
Sensitivity / hurt feelings	1.1	1.8	5.4	-0.0	2.3	1.4	-0.3	2.0	2.0	-0.7	0.5	0.1
Frequency of depressed mood in last 2 weeks	1.3	1.8	9.8	0.6	-0.2	-0.9	3.1	-0.7	-0.7	1.2	0.1	1.7
Hearing difficulty/problems: Yes	1.8	2.8	5.8	-0.2	-2.4	-0.7	1.9	-1.4	-1.2	2.4	1.4	2.0
Relative age of first facial hair	1.0	2.1	4.7	0.0	-0.2	-1.2	2.2	-1.7	-2.0	1.5	0.3	1.8
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.5	-0.6	1.1	1.1	1.1	1.0	0.6	0.1	1.6	0.6
Ever used hormone-replacement therapy (HRT)	0.4	0.6	2.0	-0.6	1.4	-0.5	0.7	-0.6	-0.3	-1.0	0.6	0.3
Ever had hysterectomy (womb removed)	0.5	0.5	1.6	-1.3	-0.4	-0.2	0.6	-0.3	0.7	-0.8	-1.1	-0.1
Systolic blood pressure, automated reading	1.9	5.6	15.7	-0.9	-0.3	-0.2	-3.9	0.7	1.5	-2.7	-2.9	-4.0
Eye problems/disorders: Diabetes related eye disease	0.5	0.5	1.8	0.8	-1.1	-0.2	1.3	-0.0	-0.8	0.4	-0.3	0.3
Angina	1.0	1.3	4.2	0.6	-1.0	-0.3	0.6	-0.3	1.9	1.4	0.4	2.1
Medication for hormone replacement therapy	0.4	0.5	2.3	0.1	1.5	-0.2	0.5	0.4	-0.9	-0.7	0.1	0.1
Vitamin and mineral supplements	0.4	0.6	1.9	-1.2	-0.6	0.0	1.4	0.3	-0.5	0.8	-0.2	-0.9
Supplements: Zinc	0.3	0.4	0.8	-0.4	0.7	-0.9	-0.9	-0.2	0.9	-0.6	0.1	0.1
Medication: Co-codamol	0.6	0.6	2.1	0.4	-0.9	-0.9	0.8	-0.6	0.8	0.2	-0.3	1.4
Medication: Metformin	0.3	0.4	1.6	-0.3	-0.1	0.2	0.0	-0.0	1.3	0.9	0.9	0.5
Diabetes (father)	0.8	1.0	5.0	0.2	0.2	0.4	-2.2	1.3	-0.2	-0.8	-1.1	-0.7
Diabetes (mother)	0.9	1.2	2.9	0.7	1.2	1.1	-0.7	1.7	-1.4	-1.0	0.9	0.6
Severe depression (siblings)	1.7	1.9	4.9	0.5	-2.2	1.8	1.1	0.1	-1.0	1.5	0.7	1.7
Pack years adult smoking proportion	0.6	0.9	4.7	-0.8	0.7	-0.2	2.2	0.2	0.1	-0.1	1.3	0.8
Impedance of leg (right)	0.7	3.2	10.8	3.3	0.6	-0.7	1.5	-1.4	1.6	2.0	0.0	2.4
Leg fat-free mass (left)	0.6	3.1	6.8	-2.1	-1.4	1.2	-0.7	1.8	-0.9	-2.6	-1.5	-2.5
Trunk fat percentage	0.2	0.8	2.3	-0.5	-0.5	0.7	1.5	1.0	0.3	0.7	1.3	0.8
Hand grip strength (right)	0.9	2.3	7.9	-0.4	-0.1	0.7	-0.9	1.0	-1.2	-2.8	-1.6	-2.6
Townsend deprivation index at recruitment	0.2	0.3	1.1	-0.5	0.3	-1.1	0.5	-0.6	-0.6	0.1	0.1	-0.3
Current tobacco smoking	0.3	0.5	2.4	-0.3	0.8	-0.2	1.6	0.2	0.3	-0.7	0.8	0.7
Average weekly fortified wine intake	1.1	1.3	4.2	1.3	-2.1	-1.2	0.2	-1.1	-0.5	-0.2	-1.1	1.3
Maternal smoking around birth	0.6	0.8	1.9	-0.8	0.3	1.3	0.4	1.0	1.4	1.0	0.9	0.3
Fed-up feelings	1.0	1.9	9.7	0.2	-0.2	0.4	3.1	0.6	0.4	1.4	0.6	2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	3.4	0.3	-0.0	-0.3	1.9	0.3	-0.6	0.9	-0.1	0.4
Relative age voice broke	1.1	1.7	6.1	-0.2	-1.0	-0.2	1.6	-0.6	-1.3	2.5	0.9	1.6
Taking other prescription medications	0.5	0.7	1.4	0.2	1.2	-0.7	1.0	-0.3	1.2	0.8	0.7	1.0
Age when periods started (menarche)	0.7	1.6	3.2	0.6	-1.8	-1.5	1.4	-1.8	-1.1	1.4	-0.3	0.0
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	3.1	-0.2	0.2	-1.4	-0.4	-0.2	-1.3	-1.4	-1.8	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	8.0	0.7	0.1	1.1	1.1	1.3	-2.8	-0.4	0.1	-0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.4	-0.3	0.1	-0.7	0.2	-0.5	-0.6	0.2	-0.5	0.2
Qualifications: CSEs or equivalent	0.7	0.9	2.5	1.2	0.9	-1.2	-1.6	-0.2	0.7	-0.1	-1.1	0.0
Serious illness, injury or assault to yourself	1.4	1.7	4.0	0.6	1.4	1.1	-1.0	2.0	0.8	0.5	-1.9	-1.5
High blood pressure	0.6	1.7	8.3	-0.3	-0.1	0.4	-2.9	0.9	0.5	-1.4	-1.4	-1.3
Hayfever, allergic rhinitis or eczema	0.3	0.8	1.5	-0.9	-0.8	-0.9	0.5	-1.2	0.1	1.1	1.0	0.7
Multivitamins +/- minerals	0.5	0.7	3.0	1.0	-1.7	-0.0	-0.2	-1.0	0.3	0.7	0.1	0.6
Stomach or abdominal pain in last month	3.0	3.8	9.9	-0.8	-0.7	1.0	3.0	-0.0	-1.2	3.1	2.2	2.6
Supplements: Glucosamine	0.5	0.6	1.9	-0.4	0.2	-0.1	-1.3	0.1	1.2	-1.4	-0.2	-0.2
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	6.7	-1.0	0.2	-0.7	1.8	-0.5	-0.3	0.9	1.6	2.6
Medication: Atenolol	0.2	0.2	1.0	0.8	-1.0	-0.1	0.2	-0.0	-0.1	-0.1	0.3	0.1
Medication: Levothyroxine sodium	1.2	2.0	7.2	-0.6	0.3	1.8	1.2	1.3	-1.2	0.5	2.7	1.5
Sitting height	0.6	4.4	19.5	2.0	-0.0	-0.7	-0.5	0.2	-0.4	-2.6	-4.4	-2.9
Chronic bronchitis/emphysema (father)	1.5	1.8	7.3	-1.1	0.2	0.8	1.0	0.3	2.7	1.6	1.2	1.3
High blood pressure (mother)	0.3	0.5	1.3	0.0	-0.8	-0.8	-0.5	-1.1	-0.8	-0.5	0.1	0.8
Body mass index (BMI)	0.7	2.9	6.4	-2.5	-0.9	1.9	2.2	1.7	-0.2	1.0	2.3	1.2
Impedance of leg (left)	0.6	3.0	15.5	3.9	1.1	-0.9	0.9	-1.4	1.1	1.6	-0.6	1.7
Leg predicted mass (left)	0.6	3.1	6.7	-2.1	-1.4	1.3	-0.7	1.8	-0.9	-2.6	-1.5	-2.5
Trunk fat mass	0.1	0.6	1.4	-1.0	-0.8	0.8	1.2	1.2	0.2	-0.3	0.5	-0.2
Waist circumference	0.3	1.2	4.1	-2.0	-0.6	0.9	1.0	1.2	0.3	-1.5	0.5	-0.0
Number of incorrect matches in round	0.2	0.4	1.1	0.8	0.2	-1.0	-0.2	-0.5	0.3	1.0	0.4	-0.1
Past tobacco smoking	0.2	0.4	1.1	-0.2	-0.4	-0.4	-0.9	-0.5	0.2	-1.0	-0.8	-0.6
Alcohol usually taken with meals	0.9	1.5	4.9	2.2	0.3	-0.4	-2.0	0.8	-0.8	-0.5	-0.8	-1.5
Nervous feelings	0.5	1.0	3.9	0.4	0.7	-2.0	-0.1	-1.1	1.0	-1.5	0.0	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	4.5	1.2	0.7	-0.4	2.1	-0.5	0.4	0.8	0.9	2.1
Hearing difficulty/problems with background noise	2.0	3.1	10.0	0.6	-1.7	0.6	2.1	-0.6	0.8	2.3	2.0	3.2
Hair/balding pattern: Pattern 2	0.9	1.1	3.7	-0.3	-0.3	-1.9	1.2	-1.6	0.7	1.2	-0.5	-0.0
Had menopause	0.6	0.8	3.6	0.5	0.1	-0.8	-0.2	-0.7	-0.8	-1.9	-0.8	-0.8
Had other major operations	0.3	0.3	1.0	-0.8	-0.3	0.9	-0.2	1.0	-0.7	0.1	-0.0	0.2
Forced vital capacity (FVC)	0.5	1.9	7.4	1.8	-1.5	1.0	2.7	-0.0	0.1	1.0	-1.3	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	8.8	0.2	0.6	0.9	0.9	1.1	-3.0	-0.6	0.4	-0.1
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	6.4	0.9	-1.1	-2.5	0.8	-2.5	1.5	1.0	-1.7	-0.5
Qualifications: None of the above	0.3	0.6	1.3	-0.2	1.0	0.0	0.9	0.1	1.1	1.1	1.2	0.4
Financial difficulties in last 2 years	1.7	2.2	6.1	-1.1	1.2	0.2	2.2	0.2	-1.4	1.5	1.6	2.5
Mouth/teeth dental problems	2.0	3.1	10.7	1.1	1.1	-0.3	-2.1	0.9	-0.6	-0.9	-2.9	-3.3
Heart attack	0.6	0.7	3.0	0.3	1.0	1.4	-0.4	1.7	0.4	-0.2	-0.2	-0.1
Allergy	0.4	1.0	2.2	1.1	-0.1	1.5	-0.5	1.3	-0.7	-0.7	-0.9	-1.3
Pain all over the body in last month	0.3	0.3	1.4	0.5	-0.4	-0.5	-0.5	-0.4	0.2	-0.8	-1.2	0.3
Diabetes (self-reported)	0.3	0.4	1.1	-0.5	-0.6	0.5	-0.6	1.0	1.1	0.4	0.3	-0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.6	0.6	-0.3	-0.7	0.5	-0.8	-0.3	-0.3	-0.1	0.6
Medication: Ramipril	0.2	0.3	0.7	-0.8	0.0	0.6	-0.2	0.8	0.4	-0.5	0.2	0.6
Medication: Simvastatin	0.4	0.6	1.8	-0.7	1.0	0.1	-0.8	0.7	1.3	0.5	0.4	-0.8
Fluid intelligence score	0.7	1.4	3.5	0.1	-1.9	-0.6	-0.1	-1.2	-1.7	-1.3	-1.4	-0.9
Illnesses of siblings	1.0	1.4	5.9	-0.9	0.9	2.4	0.2	1.9	0.1	0.5	1.2	0.0
Neuroticism score	0.3	0.5	1.6	1.0	-0.4	-1.0	1.3	-0.1	0.5	-0.4	-0.8	0.4
Weight	0.3	1.4	2.6	-1.3	-1.1	1.0	0.7	1.6	-0.2	-1.6	-0.9	-1.4
Impedance of arm (right)	0.4	1.8	9.0	3.0	1.0	-1.8	-1.1	-1.1	0.5	0.2	-0.7	-0.1
Arm fat percentage (right)	0.5	1.9	4.8	-1.6	-0.4	1.1	1.8	1.4	0.4	1.0	2.2	1.3
Trunk fat-free mass	0.9	5.4	15.7	-1.9	-0.9	1.0	-0.9	1.7	-0.2	-4.0	-3.0	-3.9
Hip circumference	0.2	1.1	2.7	-1.6	-0.7	1.4	0.8	1.6	-0.4	-0.7	0.5	-0.3
Time employed in main current job	0.9	1.1	2.7	0.1	0.3	0.8	0.7	1.1	0.9	1.6	1.6	1.1
Alcohol intake versus 10 years previously	1.0	1.5	8.1	-0.5	0.4	0.8	1.8	0.8	-2.9	0.0	0.1	-0.3
Father’s age at death	0.4	0.5	2.3	1.4	-0.2	0.3	-0.3	0.4	1.5	0.0	0.6	0.1
Worrier / anxious feelings	1.6	3.0	8.7	0.9	-1.7	-2.9	0.3	-2.2	0.5	-1.9	-2.2	-0.9
Frequency of tiredness / lethargy in last 2 weeks	1.8	2.9	11.9	-0.0	0.5	0.6	3.5	0.1	1.0	2.0	1.2	2.7
Falls in the last year	0.9	1.2	5.2	-0.6	0.7	-0.6	-0.7	-0.1	2.3	-1.5	-1.1	-0.6
Hair/balding pattern: Pattern 3	1.0	1.4	3.1	-0.3	0.8	1.6	-1.8	1.8	-1.3	-1.0	0.7	-0.3
Number of live births	0.7	1.0	2.6	-1.2	0.1	1.2	-1.3	0.9	0.9	-1.6	0.0	-0.4
Forced expiratory volume in 1-second (FEV1)	0.8	2.6	8.6	1.7	-2.5	1.3	2.9	-0.1	0.1	1.6	-0.8	0.8
Pulse rate	0.4	0.7	3.0	-0.4	0.9	-0.7	0.0	-0.5	0.1	0.7	1.7	1.0
Happiness	1.7	2.1	7.6	1.3	-1.0	-2.7	0.2	-2.7	-0.2	0.1	-1.0	0.0
Noisy workplace	0.5	0.6	1.6	0.9	1.3	0.8	0.4	1.1	0.7	-0.1	0.7	0.3
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.0	0.1	-1.7	-0.9	-1.1	-1.1	-0.5	-1.1	-1.7	-1.6
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.9	1.0	0.2	0.8	-0.1	0.7	-0.0	-0.1	-0.8	-0.4
Mouth/teeth dental problems: Dentures	1.2	2.0	3.9	-1.6	-0.4	-1.5	1.2	-2.0	1.1	-0.5	1.8	1.7
Asthma	0.4	0.8	1.8	0.6	1.1	-0.6	1.2	-0.4	-0.6	1.3	0.4	1.3
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.6	4.8	0.2	0.2	2.2	1.8	1.3	1.1	1.6	0.2	0.7
Medication: Cholesterol lowering	1.3	2.1	7.3	0.3	1.3	0.2	-2.7	1.5	2.1	-1.0	-0.7	-1.1
Depression (self-reported)	1.0	1.2	3.5	1.7	1.2	0.2	0.6	0.6	0.0	-1.9	-1.2	-0.7
Medication: Lansoprazole	0.1	0.2	0.7	0.4	0.1	0.2	0.9	0.4	0.3	-0.2	-0.2	0.2
Prospective memory result	0.4	0.5	1.5	-0.3	1.2	-0.1	0.5	0.1	0.6	-0.3	0.6	1.1
Lung cancer (father)	0.4	0.4	1.9	-0.3	-0.0	0.0	0.9	-0.1	-1.4	-0.2	0.8	0.6
Illnesses of mother	1.0	1.2	3.2	-0.5	0.7	1.8	1.6	1.3	-0.8	1.4	0.7	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	8.1	1.6	-2.5	1.5	2.8	0.2	-0.9	1.3	-0.3	1.3
Pulse wave Arterial Stiffness index	0.7	0.8	2.1	0.3	-0.9	1.0	1.2	0.4	0.7	0.9	0.5	1.4
Impedance of arm (left)	0.4	1.9	11.0	3.3	0.5	-1.6	-0.8	-1.2	0.1	0.5	-0.5	0.3
Arm fat mass (right)	0.3	1.3	3.5	-1.9	-0.5	1.3	1.5	1.7	0.0	-0.0	1.1	0.1
Trunk predicted mass	1.0	5.4	15.8	-1.9	-0.9	1.0	-1.0	1.6	-0.2	-3.9	-3.0	-4.0
Standing height	1.4	13.9	42.9	2.1	-0.8	-1.3	-3.1	0.1	0.1	-5.7	-6.5	-5.8
Length of working week for main job	1.1	1.2	9.3	0.2	-0.4	-0.1	0.9	-0.5	-3.0	0.7	-0.1	0.0
Exposure to tobacco smoke at home	0.6	0.7	2.8	0.1	0.1	-1.0	-1.7	0.4	1.3	-0.2	-0.5	-0.8
Breastfed as a baby	0.6	0.7	3.6	-1.9	-0.4	0.2	0.4	-0.6	-0.8	0.5	1.1	0.1
Tense / ‘highly strung’	0.9	1.4	7.4	1.4	0.2	-2.7	-0.2	-1.6	-0.1	-0.4	-0.7	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.2	0.5	0.1	1.0	0.7	1.1	0.2	-0.5	0.3	1.0
Hair/balding pattern: Pattern 4	0.5	1.3	4.5	0.3	-1.4	0.3	-0.6	0.3	2.1	0.0	-1.1	-1.9
Birth weight of first child	0.4	0.7	2.5	0.3	-1.3	-0.1	0.9	-0.2	0.6	0.2	0.7	1.6
Peak expiratory flow (PEF)	1.0	2.4	12.2	0.4	-1.3	1.7	3.5	0.5	0.5	1.6	0.1	1.3
Pulse wave reflection index	0.3	0.4	1.1	-0.1	0.1	1.0	1.0	0.4	0.4	0.8	-0.0	0.8
Ever highly irritable/argumentative for 2 days	1.1	1.4	4.1	0.0	0.4	-0.6	1.7	-0.5	-0.6	2.0	0.9	1.8
Loud music exposure frequency	1.0	1.1	4.0	-0.8	-0.6	-1.6	0.9	-2.0	0.4	0.6	0.4	0.9
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	1.9	0.8	-1.0	0.4	-1.3	0.8	0.4	-0.7	-0.7	-1.4
Mouth/teeth dental problems: Bleeding gums	1.4	1.9	4.8	-1.0	-2.0	0.2	1.6	-1.0	0.2	1.3	1.3	2.2
Blood clot in the leg (DVT)	0.6	0.7	2.1	-1.4	0.2	1.0	-0.8	1.4	0.4	-0.8	-0.1	0.4
Medication: Paracetamol	0.7	1.2	3.3	-0.8	-0.2	0.6	1.8	0.4	1.2	1.6	0.7	1.4
Headache pain in last month	1.0	1.8	4.7	1.3	-0.6	0.8	2.0	0.3	-0.4	1.9	0.6	2.2
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	11.8	-1.0	-1.3	-0.6	3.4	-2.0	-2.2	1.9	0.7	0.8
Glaucoma (self-reported)	0.5	0.6	2.1	-0.2	0.6	-0.2	-0.7	0.5	1.4	0.3	1.0	0.9
Gout (self-reported)	1.1	1.6	7.2	0.9	0.4	-0.5	-0.5	1.0	-0.0	-1.1	-1.8	-2.7
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	6.1	-0.4	1.5	1.4	0.4	1.6	-1.1	-0.4	2.5	1.0
Medication: Amlodipine	0.6	0.8	2.8	-0.1	0.8	-0.2	-1.1	0.5	-0.2	0.5	-1.7	-1.4
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.7	0.3	0.1	-1.3	0.0	-1.2	0.3	1.2	-1.1	0.7
Birth weight	0.2	0.5	2.4	-0.4	-0.8	-0.4	0.5	-0.7	1.6	0.1	0.1	0.0
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.7	0.1	-0.3	0.4	-0.2	0.4	1.1	-0.4	1.1	1.3
High blood pressure (siblings)	0.6	0.9	1.9	1.4	-0.8	-0.5	-0.8	0.4	-0.6	-1.2	-1.3	-1.2
Forced vital capacity (FVC), Best measure	0.5	1.9	8.5	1.2	-2.0	1.1	2.9	-0.0	-0.6	1.0	-0.6	0.9
Body fat percentage	0.4	1.5	4.0	-0.8	-0.5	1.0	2.0	1.1	0.4	1.2	1.8	1.4
Leg fat percentage (right)	1.1	4.1	12.8	-1.0	-0.7	1.2	3.6	0.7	0.5	2.3	2.6	2.9
Arm fat-free mass (right)	0.6	2.8	7.0	-1.5	-1.5	1.1	0.0	1.3	-0.5	-2.6	-2.1	-2.5
Exposure to tobacco smoke outside home	1.5	1.9	7.7	-2.8	0.5	-1.4	0.1	-1.2	1.7	-1.8	0.1	-0.1
Comparative body size at age 10	1.3	3.5	7.6	-0.9	1.3	2.6	1.6	2.8	0.9	1.6	2.7	1.1
Number of full brothers	1.4	1.7	3.6	-1.9	-0.8	-0.4	1.1	-0.7	-1.4	1.2	1.8	1.6
Worry too long after embarrassment	0.8	1.4	4.5	1.0	-0.4	-0.9	-0.7	0.3	0.1	-2.1	-2.0	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.6	-0.2	0.8	-0.7	0.7	-0.4	0.1	-0.6	-0.4	-0.6
Wheeze or whistling in the chest in last year	1.0	1.9	7.8	-0.2	-0.6	-0.1	2.8	-1.1	0.9	0.7	1.1	2.2
Number of children fathered	0.7	0.8	3.8	1.0	-2.0	0.9	-0.1	0.4	-0.7	1.1	0.2	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	3.7	-0.5	0.1	-0.6	-1.3	0.1	-0.6	-1.4	-1.2	-1.9
Age at first live birth	0.5	0.9	2.0	0.4	-1.4	1.0	-0.3	-0.2	1.4	0.7	-0.9	-1.2
Pulse wave peak to peak time	0.9	1.1	2.8	-0.2	0.7	-1.2	-1.5	-0.5	-0.6	-1.2	-0.8	-1.7
Health satisfaction	1.3	1.6	3.9	0.2	-1.5	-1.7	1.1	-1.8	0.6	0.8	0.3	2.0
Shortness of breath walking on level ground	0.8	0.9	3.4	0.3	0.3	-1.9	1.4	-1.3	0.1	-0.2	-0.8	0.4
Qualifications: College or University degree	0.5	1.6	10.1	0.6	-0.5	0.6	-0.4	0.3	-3.2	-1.3	-1.1	-0.7
Eye problems/disorders: None of the above	0.9	1.0	4.5	-0.7	-1.3	0.5	2.1	-0.7	0.4	1.1	0.6	0.4
Mouth/teeth dental problems: Loose teeth	2.2	2.6	5.3	1.2	-1.3	1.5	2.1	0.6	0.6	2.3	2.0	1.9
Emphysema/chronic bronchitis	0.6	0.7	2.7	-0.7	-0.6	-0.1	0.9	-1.2	1.6	-0.1	0.5	0.6
Medication for pain relief, constipation, heartburn	2.1	3.7	18.2	-0.5	-0.4	-1.7	-1.0	-1.2	-4.3	-2.3	-0.8	-1.9
Neck or shoulder pain in last month	3.8	5.4	12.8	-1.8	0.4	-0.8	2.8	-1.6	2.3	3.6	2.8	2.9
Medication: Blood pressure	1.5	2.6	8.7	1.0	0.7	0.3	-3.0	1.6	2.3	-2.0	-0.8	-0.6
Angina (self-reported)	0.9	1.1	3.6	0.9	-1.0	-0.3	0.5	-0.3	1.6	1.3	0.2	1.9
Migraine (self-reported)	0.4	0.5	2.5	0.3	-1.6	1.1	0.4	0.3	-0.2	0.8	-0.4	0.0
Medication: Ibuprofen	1.3	1.6	5.3	0.5	0.2	2.3	1.6	1.2	0.9	1.6	0.1	1.1
Medication: Allopurinol	1.5	2.0	7.9	0.4	0.6	-0.7	-1.4	0.6	0.1	-1.4	-2.1	-2.8
Medication: Omeprazole	0.8	1.0	4.6	0.6	-0.2	0.4	1.0	0.2	2.2	0.4	0.9	1.3
Medication: Seretide 50 evohaler	0.5	0.6	2.2	-0.6	-0.0	-0.3	-0.9	0.7	1.0	-0.6	-0.7	-1.5
Mean time to correctly identify matches	0.6	1.1	4.0	-0.1	-0.7	-2.0	0.5	-1.6	0.9	-0.4	-1.0	1.0
Heart disease (mother)	0.7	0.9	2.5	0.7	-1.0	-1.5	-0.5	-1.0	1.6	-0.6	0.1	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.7	4.4	16.2	-1.7	0.7	1.3	1.5	0.5	1.3	2.5	4.0	2.7
Whole body fat mass	0.2	0.8	2.0	-1.4	-0.8	0.9	1.4	1.2	0.2	-0.1	0.8	-0.0
Leg fat mass (right)	0.4	1.7	4.7	-1.5	-0.9	1.4	2.2	1.4	0.3	0.6	1.4	0.8
Arm predicted mass (right)	0.7	3.4	8.1	-1.5	-1.4	1.4	-0.3	1.6	-0.3	-2.9	-2.5	-2.7
Pulse rate, automated reading	0.7	2.2	8.6	-0.5	0.5	-0.1	0.3	-0.2	1.6	0.3	2.8	2.9
Alcohol intake frequency.	0.7	1.5	7.9	2.2	0.3	-0.4	0.4	0.4	-2.8	-0.6	-0.0	-0.1
Comparative height size at age 10	1.3	7.0	20.7	1.4	-0.2	-0.9	-2.1	-0.3	0.7	-4.5	-4.4	-3.9
Number of full sisters	0.5	0.6	1.7	0.7	0.8	1.3	-0.6	1.2	0.5	-0.2	0.9	-0.0
Suffer from ‘nerves’	1.2	1.9	8.1	0.6	-0.4	-2.8	1.2	-2.0	-0.2	-0.0	1.2	1.2
Overall health rating	0.2	0.5	1.9	-0.9	0.5	-0.2	1.4	0.2	0.8	0.1	0.9	0.7
Chest pain or discomfort	1.9	2.7	7.9	0.2	0.1	-0.3	2.7	-0.6	0.3	2.3	1.7	2.8
Had major operations	0.2	0.3	1.3	-0.4	-0.1	0.3	-0.2	0.8	-0.2	0.3	0.1	-1.1
Age at last live birth	0.6	0.8	1.6	-1.2	-1.1	0.8	-0.7	0.2	1.2	0.3	-0.7	-1.2
Family relationship satisfaction	2.0	2.4	8.1	-0.6	0.6	-2.9	1.2	-2.7	-0.7	1.2	0.9	1.2
Leg pain on walking	0.5	0.6	2.4	-0.3	-0.6	-1.6	0.3	-0.6	1.2	0.8	0.1	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.4	0.9	-1.0	-0.4	1.2	-0.8	-0.3	1.1	-0.2	0.2
Commuting to job workplace: Car/motor vehicle	1.2	1.4	4.2	-0.2	1.9	1.9	-0.4	2.0	-0.3	-0.2	1.1	-0.1
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	1.5	-0.1	-1.1	-1.2	-0.9	-1.2	-0.5	-0.9	-0.5	-1.0
Medication: Aspirin	1.2	1.6	5.9	1.1	-0.5	0.8	-2.4	0.6	2.4	0.2	-0.4	0.3
Supplements: Vitamin C	0.8	0.9	1.8	-0.6	1.4	-1.1	-1.1	-1.1	-0.4	-1.3	0.3	0.2
Knee pain experienced in last month	1.7	2.7	8.2	-0.2	-0.2	-1.2	2.1	-1.5	2.1	1.6	0.8	2.9
Hypertension (Self-reported)	0.6	1.5	6.6	-0.1	-0.0	0.1	-2.6	0.9	0.9	-1.1	-1.6	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.5	-0.1	-1.6	-1.0	-0.1	-1.0	0.6	1.0	-0.9	0.1
Illnesses of father: Heart disease	0.4	0.6	4.1	0.1	-0.7	0.4	-0.2	0.4	2.0	0.1	0.5	0.4
Illnesses of siblings: Diabetes	1.0	1.2	2.4	-0.4	-1.3	-1.5	1.3	-1.5	-0.0	1.3	-0.3	0.9
Smoking status: Previous	0.1	0.2	0.4	0.3	-0.1	0.4	0.1	0.5	-0.6	0.6	0.4	0.0
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.4	5.8	1.8	-1.2	1.5	-0.3	1.4	-0.5	-2.4	-1.9	-1.6
Whole body fat-free mass	0.8	4.4	11.4	-2.0	-1.2	1.2	-0.8	1.8	-0.6	-3.4	-2.4	-3.4
Leg fat-free mass (right)	0.7	3.6	9.2	-1.7	-1.2	1.0	-1.0	1.6	-1.3	-2.9	-2.1	-3.0
Arm fat percentage (left)	0.6	2.3	6.6	-1.4	-0.6	1.2	2.0	1.4	0.1	1.3	2.6	1.7
Average weekly red wine intake	0.9	1.3	7.2	-0.4	-2.7	-0.6	-1.1	-1.6	-0.6	0.1	-0.3	0.0
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.1	0.2	1.1	0.4	-0.3	0.6	0.5	0.6	0.4	0.2
Mood swings	1.4	2.6	10.2	0.1	-0.7	-0.9	3.2	-1.4	1.2	1.5	0.3	2.5
Loneliness, isolation	0.4	0.6	2.8	0.7	-0.1	-0.9	0.4	-0.3	0.1	1.7	0.5	0.9
Long-standing illness, disability or infirmity	0.3	0.5	2.5	-0.1	1.6	0.2	0.9	0.4	1.0	0.2	0.0	0.3
Ever had bowel cancer screening	1.3	1.5	2.9	-1.4	-0.6	-0.8	-1.6	-0.7	-0.4	-1.7	-1.4	-1.7
Diabetes diagnosed by doctor	0.2	0.4	1.3	-0.9	0.0	0.7	-0.3	1.1	0.4	-0.1	0.9	0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	3.3	-0.1	-1.8	0.8	-0.3	-0.2	1.2	-0.2	0.5	0.6
Friendships satisfaction	0.5	0.6	2.7	0.2	-0.3	-0.6	0.4	-0.5	-1.6	0.2	0.8	1.0
Qualifications: nursing, teaching	0.3	0.5	0.9	-0.5	-0.5	-0.6	-0.7	-1.0	-0.8	-0.8	-0.1	-0.8
Commuting to job workplace: Walk	1.8	1.9	5.0	0.7	-1.8	-2.2	-1.1	-2.2	0.7	-0.2	-1.0	-0.9
Eye problems/disorders: Cataract	0.6	0.7	2.7	-0.8	0.8	0.0	-1.6	0.1	-0.9	-1.4	-0.2	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.2	0.7	-0.2	0.2	0.5	0.4	0.5	0.2	-0.2	1.1
Medication for cholesterol	0.1	0.2	0.7	0.0	-0.7	-0.0	-0.2	-0.5	0.2	0.8	0.2	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	4.2	-2.1	-0.1	0.9	1.1	1.2	1.8	1.0	0.7	0.5
Back pain experienced in last month	0.3	0.5	1.6	0.4	0.4	-0.1	1.3	-0.7	-0.7	0.5	0.7	0.8
Mineral and other dietary supplements	0.7	0.9	2.9	-0.6	0.5	0.2	1.7	0.2	-1.5	1.4	0.6	0.2
Breast cancer (self-reported)	0.4	0.5	2.1	-1.0	-0.0	0.0	0.2	-0.4	-0.9	0.3	1.4	0.5
Asthma (self-reported)	0.4	0.9	2.2	0.7	1.0	-0.7	1.2	-0.4	-0.3	1.3	0.5	1.5
Osteoporosis (self-reported)	1.1	1.3	3.0	-1.3	0.5	-0.7	1.3	-1.0	1.4	1.7	0.6	1.3
Osteoarthritis (self-reported)	1.0	1.2	4.0	-0.7	1.7	0.0	-0.6	0.9	1.5	-2.0	-0.4	-0.4
Medication: Aspirin	1.2	1.5	6.2	1.2	-0.6	0.9	-2.5	0.5	2.1	0.1	-0.4	0.4
Medication: Gliclazide	0.6	0.7	1.9	1.4	-1.1	0.6	0.5	0.6	1.0	0.5	0.5	-0.2
Illnesses of father: None of the above (group 1)	1.2	1.5	8.4	-0.1	0.3	-1.2	0.9	-0.6	-2.9	-0.2	-0.3	-1.3
Smoking status: Current	0.3	0.5	2.5	-0.2	0.7	-0.2	1.6	0.2	0.3	-0.7	0.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.6	7.3	-0.2	-2.7	0.7	2.7	-0.9	0.5	1.4	0.9	2.2
Whole body water mass	0.8	4.3	11.4	-2.0	-1.2	1.2	-0.8	1.7	-0.5	-3.4	-2.4	-3.3
Leg predicted mass (right)	0.7	3.6	8.9	-1.7	-1.2	1.1	-1.0	1.7	-1.4	-2.9	-1.9	-3.0
Arm fat mass (left)	0.3	1.3	3.2	-1.8	-0.6	1.3	1.4	1.7	-0.0	0.1	1.2	0.1
Number of self-reported non-cancer illnesses	0.5	0.8	3.3	-0.8	1.8	-0.5	-0.3	0.7	0.6	-1.3	-0.9	-0.2
Average weekly champagne plus white wine intake	0.3	0.4	1.5	0.0	-0.4	0.5	-0.8	1.0	-1.2	-0.3	-0.1	-0.5
Miserableness	0.4	0.7	2.8	0.6	-1.3	0.0	1.7	-0.4	-0.4	-0.1	-0.3	1.0
Guilty feelings	1.2	1.8	9.1	1.6	-1.2	0.5	0.2	0.8	1.4	-0.5	-3.0	-0.2
Wears glasses or contact lenses	1.0	1.1	2.4	-0.6	0.6	-1.5	-0.4	-1.1	-1.5	-0.9	-0.7	-1.4
Ever taken oral contraceptive pill	0.6	0.7	2.8	-0.5	0.7	-0.5	-1.1	0.2	1.0	-1.7	0.1	0.2
Hearing aid user	0.7	0.8	3.0	-0.7	-1.1	-0.5	1.7	-0.9	-0.0	0.8	0.7	0.2
Mother’s age at death	2.5	3.2	6.7	2.3	0.4	-2.6	-1.3	-1.6	-0.9	-1.7	-2.3	-1.8
Financial situation satisfaction	0.4	0.6	1.5	0.1	-0.4	-0.5	1.2	-1.2	-0.4	0.0	-0.5	1.1
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.3	-1.3	0.8	-0.2	1.7	-0.4	0.7	0.8	1.8	1.3
Commuting to job workplace: Public transport	0.3	0.4	1.6	-0.8	1.3	-0.2	0.0	-0.1	0.2	-0.3	0.5	0.8
Eye problems/disorders: Glaucoma	0.5	0.6	2.1	-0.6	0.3	-0.3	0.1	0.1	0.9	0.9	1.4	1.1
Medication: Blood pressure	0.0	0.0	0.1	-0.1	-0.3	0.1	-0.2	0.2	-0.2	-0.1	-0.2	0.1
Pain type(s) experienced in last month: Hip pain	0.9	1.2	4.5	-2.1	1.1	0.8	0.6	0.6	1.1	0.5	1.2	0.7
Supplements: Fish oil (including cod liver oil)	1.1	1.5	4.4	-0.3	-0.3	-0.2	-2.1	0.2	1.7	-1.8	-1.1	-1.2
High cholesterol (Self-reported)	0.2	0.4	1.3	-0.1	1.0	0.4	-0.8	0.8	1.1	-0.2	-0.2	-0.1
Medication: Bendroflumethiazide	1.2	1.9	4.4	0.1	-0.8	-2.0	-1.9	-1.0	0.7	-1.3	-2.1	-1.1
Medication: Paracetamol	1.2	1.8	3.8	-0.8	0.0	0.7	1.7	0.4	1.8	1.9	1.4	2.0
Medication: Lisinopril	0.7	0.9	2.4	1.4	1.4	-0.5	-1.5	0.3	1.2	-0.2	-0.1	0.3
Medication: Atorvastatin	0.9	1.1	3.1	-1.0	-0.3	0.1	-1.4	0.5	0.4	-1.8	-1.1	-1.4
Illnesses of father: High blood pressure	1.4	1.7	4.5	0.5	1.7	2.1	-1.7	1.7	0.8	0.2	0.8	0.6
Alcohol drinker status: Never	0.6	0.7	3.9	-0.6	-2.0	-0.3	-0.4	-0.0	0.1	-0.7	-0.3	-1.1
Ever smoked	0.8	1.4	4.4	-0.2	0.6	0.4	2.1	0.3	-0.0	1.8	1.4	1.5
Basal metabolic rate	0.7	3.6	9.0	-1.8	-1.2	1.3	-0.4	1.9	-0.6	-3.0	-2.1	-3.0
Leg fat percentage (left)	0.8	2.9	8.6	-0.5	-0.4	1.1	2.9	0.8	0.2	2.0	2.3	2.3
Arm fat-free mass (left)	0.7	3.4	8.5	-1.8	-1.1	1.1	-0.3	1.6	-0.2	-2.9	-2.4	-2.9
Number of operations (self-reported)	0.1	0.2	0.5	0.4	0.7	-0.4	-0.4	0.1	-0.5	0.6	0.1	0.1
Average weekly beer plus cider intake	0.9	1.3	4.6	-1.4	0.0	-0.6	2.1	-0.5	-0.3	0.2	1.7	1.2
Irritability	0.4	0.8	1.8	-0.6	1.1	-0.7	1.3	-0.2	0.3	-1.0	-0.1	1.3
Risk taking	2.4	3.5	11.6	-0.1	0.5	3.4	1.0	3.2	1.2	2.0	1.7	0.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.4	-0.4	-1.2	-0.4	0.2	-0.4	0.5	0.7	0.3	0.1
Fractured/broken bones in last 5 years	1.4	1.8	3.6	-1.6	1.4	-1.1	-1.9	-0.2	0.2	-1.7	-0.9	-1.8
Age started oral contraceptive pill	1.0	1.2	5.0	-0.1	1.0	-2.2	0.4	-1.4	0.6	-1.4	-0.6	-0.2
Diastolic blood pressure, automated reading	0.2	0.7	2.5	-1.6	-1.0	0.6	0.2	0.2	0.8	0.2	1.2	0.9
Ever depressed for a whole week	0.6	0.7	2.0	0.1	-0.5	-0.8	0.3	-1.0	1.4	0.8	-1.2	-0.1
Unable to work because of sickness or disability	0.4	0.5	1.8	0.2	0.9	0.5	-0.1	0.8	1.4	-0.8	-0.6	-0.1
Commuting to job workplace: Cycle	2.2	2.7	11.4	2.0	-1.7	0.8	-1.0	0.7	-0.4	-1.0	-3.4	-1.7
Myopia	0.7	1.1	3.2	-1.2	0.3	-0.1	-0.2	0.5	1.8	1.0	1.4	-1.3
Vascular/heart problems diagnosed by doctor	0.6	1.6	7.9	-0.2	-0.2	-0.8	2.8	-1.5	-0.4	1.1	1.2	0.9
Cholesterol lowering medication	0.9	1.3	3.0	-1.2	-0.4	1.7	1.3	1.0	0.8	0.5	1.4	1.2
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	4.6	0.7	0.1	0.0	0.7	-0.1	2.2	0.4	1.2	1.3
Pain experienced in last month	3.7	6.2	15.9	1.2	1.4	0.5	-3.5	1.9	-1.4	-3.7	-2.2	-4.0
Supplements: Calcium	0.5	0.5	2.1	1.4	0.5	-0.5	-0.9	-0.5	0.7	0.4	0.1	0.7
Basal cell carcinoma (self-reported)	1.4	1.7	8.0	-0.7	0.5	0.5	-2.8	1.2	-0.2	-1.5	-0.5	-1.4
Heart attack/myocardial infarction (self-reported)	0.6	0.8	3.3	0.5	1.0	1.5	-0.5	1.8	0.2	-0.1	-0.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.3	-1.3	0.2	1.1	-0.9	1.5	0.6	-0.8	-0.3	0.2
Heart disease (siblings)	1.2	1.4	3.2	1.8	-0.9	-1.8	-0.2	-1.6	0.8	-0.6	-0.5	1.2
Alcohol drinker status: Previous	0.5	0.6	2.0	1.2	1.4	-0.8	-0.2	-0.1	0.3	0.1	-0.5	0.8
Pack years of smoking	0.5	0.7	3.4	-0.8	0.7	-0.4	1.8	0.1	0.3	-0.4	0.9	0.4
Impedance of whole body	0.5	2.4	14.3	3.8	0.9	-1.3	-0.1	-1.3	0.7	1.2	-0.4	1.2
Leg fat mass (left)	0.3	1.3	3.0	-1.3	-0.6	1.5	1.7	1.6	0.0	0.4	1.1	0.4
Arm predicted mass (left)	0.7	3.7	9.6	-1.7	-1.1	1.2	-0.6	1.7	-0.1	-3.1	-2.5	-3.0