Hub : Genes

TIFA

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0920	0.0280	4.6e-08	0.093	0.066	0.085	0.075	0.087	1.9e-11	1.7e-08	1.7e-10	2.2e-09	1.0e-10
2	GTEx	Artery Tibial	0.0736	0.0374	8.1e-03	0.059	NA	0.025	NA	0.043	2.2e-05	NA	4.6e-03	NA	2.7e-04
3	GTEx	Brain Cerebellar Hemisphere	0.1750	0.0710	1.6e-03	0.076	NA	-0.005	NA	0.061	5.5e-03	NA	4.4e-01	NA	1.2e-02
4	GTEx	Brain Cerebellum	0.3960	0.1170	1.9e-05	0.181	NA	0.120	NA	0.127	4.9e-06	NA	2.1e-04	NA	1.4e-04
5	GTEx	Esophagus Mucosa	0.1980	0.0540	2.0e-07	0.155	NA	0.140	NA	0.127	1.4e-10	NA	1.3e-09	NA	8.3e-09
6	GTEx	Esophagus Muscularis	0.1080	0.0440	8.2e-04	0.069	NA	0.038	NA	0.012	5.5e-05	NA	2.4e-03	NA	5.9e-02
7	GTEx	Heart Atrial Appendage	0.2090	0.0690	8.7e-05	0.132	NA	0.105	NA	0.142	1.6e-06	NA	1.9e-05	NA	6.2e-07
8	GTEx	Heart Left Ventricle	0.3669	0.0792	1.4e-06	0.014	NA	0.030	NA	0.073	5.7e-02	NA	1.0e-02	NA	1.0e-04
9	GTEx	Nerve Tibial	0.0633	0.0332	9.4e-03	0.008	NA	0.013	NA	0.004	8.3e-02	NA	3.8e-02	NA	1.5e-01
10	GTEx	Testis	0.4430	0.0830	4.6e-05	0.052	NA	-0.001	NA	-0.006	2.4e-03	NA	3.6e-01	NA	8.1e-01
11	NTR	Blood	0.0544	0.0186	6.9e-09	0.033	0.028	0.036	0.029	0.035	4.9e-11	2.1e-09	1.2e-11	7.2e-10	1.4e-11
12	ROSMAP	Brain Pre-frontal Cortex	0.0744	0.0217	8.7e-11	0.092	0.050	0.094	0.037	-0.002	6.6e-12	4.8e-07	4.3e-12	1.5e-05	6.4e-01
13	YFS	Blood	0.0305	0.0119	3.9e-06	0.025	0.021	0.019	0.021	0.020	1.1e-08	1.6e-07	5.2e-07	1.4e-07	2.5e-07
14	TCGA	Breast Invasive Carcinoma	0.0127	0.0078	4.2e-03	0.010	0.007	0.000	NA	0.003	3.6e-03	1.0e-02	2.5e-01	NA	8.4e-02
15	TCGA	Colon Adenocarcinoma	0.0970	0.0370	7.8e-07	0.145	0.112	0.117	NA	0.130	9.3e-09	5.4e-07	2.9e-07	NA	5.8e-08
16	TCGA	Head and Neck Squamous Cell Carcinoma	0.0602	0.0322	3.0e-05	0.034	0.029	0.021	NA	0.020	9.5e-05	2.7e-04	1.8e-03	NA	2.1e-03
17	TCGA	Brain Lower Grade Glioma	0.0375	0.0168	2.4e-05	0.050	0.029	0.039	NA	0.019	2.4e-06	2.7e-04	2.8e-05	NA	2.9e-03
18	TCGA	Pheochromocytoma and Paraganglioma	0.0890	0.0510	3.2e-03	0.059	0.029	0.022	NA	0.022	2.4e-03	2.5e-02	4.3e-02	NA	4.4e-02
19	TCGA	Prostate Adenocarcinoma	0.0388	0.0193	1.1e-04	0.014	0.043	0.039	NA	0.030	1.2e-02	2.4e-05	5.2e-05	NA	3.9e-04
20	TCGA	Testicular Germ Cell Tumors	0.0950	0.0470	1.5e-03	0.129	-0.005	0.119	NA	-0.006	2.7e-05	5.4e-01	5.7e-05	NA	6.2e-01
21	TCGA	Thyroid Carcinoma	0.1050	0.0380	4.6e-13	0.138	0.120	0.127	NA	0.136	2.3e-13	1.1e-11	2.2e-12	NA	3.5e-13

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21
Bipolar Disorder (2018)	0.0	0.1	0.5	0.0	-0.1	0.0	-0.1	-0.0	0.0	0.0	-0.5	-0.7	0.0	0.1	-0.1	0.6	0.2	-0.1	0.5	0.0	0.0	0.4	0.1	-0.1
Bipolar Disorder or Schizophrenia	0.0	0.1	0.3	-0.0	-0.0	0.2	-0.2	0.1	-0.3	-0.1	-0.6	-0.3	0.0	-0.3	-0.2	0.2	-0.3	-0.1	-0.0	-0.1	-0.1	-0.2	-0.1	-0.4
Depressed Affect (Nagel 2018)	0.0	0.1	0.8	-0.0	-0.0	-0.1	0.0	-0.4	-0.1	-0.1	0.0	-0.0	0.0	-0.4	-0.3	0.0	-0.7	0.2	-0.0	-0.1	-0.5	-0.9	-0.1	0.1
Depression (Nagel 2018)	0.1	0.1	0.6	-0.1	0.3	0.3	0.2	-0.3	-0.2	-0.0	-0.3	-0.8	0.0	-0.7	-0.1	-0.2	-0.3	-0.1	0.1	0.1	-0.3	-0.4	-0.1	-0.0
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.1	0.6	0.5	0.5	0.7	-0.6	0.7	0.8	0.4	0.8	0.5	0.7	0.6	-0.2	-1.0	-0.9	-0.4	0.9	0.1	-0.6	0.7	-0.9
Neuroticism (Nagel 2018)	0.1	0.3	1.3	-0.5	-0.4	-0.5	-0.5	0.1	-0.4	-0.4	-0.1	-1.0	0.0	-0.9	-0.7	0.6	-0.9	0.6	0.0	-0.6	-1.1	-0.7	-0.4	0.2
Schizophrenia (2018)	0.0	0.1	0.4	-0.0	0.0	0.3	-0.2	0.2	-0.4	-0.1	-0.3	0.1	0.0	-0.5	-0.2	-0.2	-0.6	-0.1	-0.4	-0.1	-0.2	-0.6	-0.1	-0.5
Schizophrenia vs Biploar Disorder	2.1	2.8	6.2	1.7	1.8	1.6	1.7	-1.6	0.9	1.4	1.6	1.6	0.0	1.0	1.4	-2.0	-2.2	-1.8	-2.3	1.6	1.7	-2.5	1.5	-1.8
Worry (Nagel 2018)	0.0	0.1	0.4	-0.2	-0.2	-0.2	-0.3	0.2	-0.1	-0.2	0.4	-0.6	0.0	-0.0	-0.4	0.5	-0.3	0.2	0.2	-0.3	-0.6	0.3	-0.2	0.2
Alzheimer’s Disease (in mother)	2.4	2.8	6.5	-1.6	-1.7	-2.5	-1.6	1.6	-1.9	-1.6	-1.0	-1.3	0.0	-1.4	-1.7	1.1	1.8	1.9	2.1	-1.7	-1.7	2.5	-1.6	1.5
Alzheimer’s Disease (in father)	0.7	0.8	1.3	-0.9	-1.0	-0.9	-1.1	0.4	-1.1	-0.9	-1.1	-0.9	0.0	-1.1	-1.1	0.6	1.0	0.9	0.4	-0.9	-0.7	0.8	-0.8	0.8
Alzheimer’s Disease (including proxy)	1.8	2.6	6.2	-1.5	-1.8	-2.5	-1.5	1.0	-1.8	-1.6	-1.2	-1.5	0.0	-1.4	-1.7	1.0	1.8	1.8	1.6	-1.7	-1.5	2.5	-1.5	1.6
Crohns Disease (2017)	0.8	1.9	4.9	1.4	1.4	1.8	1.2	-1.5	1.1	1.3	0.9	1.9	-1.7	1.4	1.5	-1.4	0.1	-1.3	-0.8	1.5	2.2	-0.4	1.4	-0.7
Irritable Bowel Disease (IBD)	0.8	1.9	4.5	1.3	1.4	1.5	1.4	-2.0	0.9	1.4	0.6	2.0	-2.1	1.0	1.4	-1.6	-0.3	-1.4	-0.9	1.6	1.9	-0.7	1.4	-0.8
Ulcerative Colitis (UC)	0.4	0.8	3.1	0.7	0.9	0.6	0.8	-1.8	0.4	0.8	0.1	1.4	-1.2	0.2	0.8	-1.0	-0.7	-0.8	-0.6	1.0	0.6	-0.9	0.8	-0.5
Major Depression (MDD)	0.2	0.2	1.1	0.3	0.3	0.0	0.2	0.2	0.3	0.2	1.1	0.6	0.0	0.0	0.1	-1.1	-0.7	-0.2	0.2	0.2	-0.5	-0.6	0.2	-0.1
Reaction Time	0.1	0.2	1.2	0.0	-0.3	0.4	-0.4	1.1	0.1	-0.3	0.5	0.0	-1.1	0.5	-0.2	0.1	0.0	0.1	0.3	-0.2	0.2	0.3	-0.2	-0.3
Verbal and Numeric Reasoning (VNR)	0.7	1.6	3.4	1.3	1.2	1.5	1.6	-1.2	1.6	1.4	0.5	0.8	0.4	1.9	1.4	-0.6	-1.0	-1.5	-1.0	1.6	1.3	-0.5	1.4	-1.4
Breast Cancer	2.8	6.7	10.8	-2.8	-2.8	-3.0	-2.6	2.6	-3.3	-2.7	-2.5	-1.8	-0.9	-2.6	-2.9	2.6	2.7	2.6	2.1	-2.8	-2.1	2.2	-2.8	2.7
Ovarian Cancer	0.4	0.6	1.6	0.7	0.8	0.5	0.7	-0.6	1.0	0.7	0.5	1.1	1.3	0.9	0.5	-0.8	-0.4	-0.8	-0.0	0.8	0.7	-0.1	0.7	-0.7
Prostate Cancer	0.2	0.2	2.0	-0.0	0.1	0.2	0.3	-0.2	-0.2	0.3	-0.6	0.4	-1.4	-0.3	0.2	0.0	-0.5	-0.2	-0.6	0.0	0.1	-0.9	0.3	0.1
Age at First Birth	1.2	1.8	3.7	1.4	1.2	1.7	1.4	-1.3	1.5	1.2	1.4	-0.0	0.3	1.2	1.2	-1.2	-1.0	-1.5	-1.8	1.4	1.9	-1.3	1.3	-1.4
Bipolar Disorder (2011)	1.0	0.9	2.3	-0.7	-0.9	-1.3	-1.3	0.6	-0.7	-0.8	-1.5	-1.0	0.0	-0.6	-0.9	1.2	1.0	0.9	1.4	-0.9	0.0	1.2	-0.8	0.8
Body Mass Index (BMI) (2010)	0.3	0.5	0.9	-0.8	-0.7	-0.6	-0.5	0.8	-0.6	-0.9	-0.8	0.3	0.0	-0.8	-0.6	0.9	0.9	0.8	0.5	-0.8	-0.3	0.5	-0.8	0.8
Coronary Artery Disease (CAD)	0.2	0.2	1.2	0.2	0.1	-0.3	0.2	0.4	0.4	0.1	1.1	0.8	0.0	0.5	0.3	-0.3	-0.2	-0.0	-0.7	0.2	0.6	0.3	0.3	-0.4
Crohns Disease (2012)	0.7	1.1	3.9	1.0	1.0	1.6	1.0	-0.3	1.0	1.0	0.3	1.3	0.0	1.3	1.1	-1.2	1.3	-0.9	0.0	1.0	2.0	0.6	1.1	-0.2
Mean Putamen Volume	0.4	0.5	1.3	0.7	0.6	0.5	0.4	-1.1	0.7	0.7	0.8	0.9	0.0	0.5	0.5	-0.4	-1.1	-0.5	-0.7	0.5	0.4	-1.0	0.6	-0.9
Fasting Glucose	0.1	0.1	0.4	-0.2	-0.1	-0.6	-0.1	-0.6	-0.1	-0.3	0.2	-0.6	0.1	-0.2	-0.1	-0.0	0.2	0.1	0.3	-0.3	0.1	0.4	0.2	-0.5
HbA1C	0.7	0.8	2.2	-1.0	-0.8	-1.5	-0.9	0.9	-1.1	-1.0	-0.2	0.3	0.0	-1.3	-0.9	0.0	0.3	1.0	0.8	-0.9	-1.4	0.1	-0.9	0.8
HDL Cholesterol	0.5	0.8	2.4	1.1	0.9	0.5	0.8	-1.1	0.8	1.0	1.3	0.2	0.0	0.8	0.7	-1.5	-0.7	-1.0	-0.4	0.8	0.8	-1.0	1.0	-0.9
LDL Cholesterol	0.2	0.2	0.8	0.5	0.3	0.4	0.3	-0.9	0.5	0.6	0.3	-0.6	0.0	0.6	0.5	-0.1	-0.1	-0.3	-0.8	0.5	0.7	-0.6	0.5	0.2
Lupus	1.0	1.5	3.5	1.1	1.5	0.7	1.4	-0.7	1.3	1.4	1.9	1.6	0.0	1.2	1.2	-1.5	-1.1	-1.3	-1.2	1.4	1.4	-0.6	1.4	-0.9
Neuroticism (2016)	0.2	0.3	1.5	-0.5	-0.3	-0.3	-0.3	0.5	-0.6	-0.7	-0.4	0.1	0.0	-0.8	-0.8	0.7	-0.3	0.4	0.4	-0.6	-1.2	-0.2	-0.6	0.5
Primary Biliary Cirrhosis	0.6	0.8	4.0	-0.5	-0.3	-0.8	-0.8	0.2	-0.6	-0.7	-0.3	-1.6	0.0	-0.2	-1.1	0.4	1.5	0.3	1.8	-0.4	-0.6	2.0	-0.5	0.1
Rheumatoid Arthritis	0.8	1.0	2.4	-1.1	-0.9	-1.5	-0.6	1.3	-1.1	-1.2	-0.6	-1.5	0.0	-0.9	-1.3	0.5	0.9	1.0	0.8	-1.1	-1.0	0.7	-1.1	1.2
Schizophrenia (2014)	0.2	0.5	1.6	0.6	0.8	0.8	0.5	-0.2	0.3	0.5	0.6	-0.0	0.0	0.4	0.4	-0.6	-1.2	-0.7	-1.3	0.5	0.7	-0.9	0.6	-1.2
Triglycerides	1.3	2.1	3.8	-1.6	-1.8	-1.2	-1.5	1.2	-1.6	-1.7	-1.4	-1.2	0.0	-1.4	-1.3	1.4	1.5	1.6	1.4	-1.4	-1.5	1.1	-1.6	1.9
Type 2 Diabetes (T2D) (2012)	0.1	0.1	1.3	-0.0	0.3	0.0	0.2	-0.0	0.0	-0.1	1.1	0.7	0.0	-0.0	0.0	-0.5	-0.1	-0.2	-0.1	0.2	0.0	0.3	0.1	-0.1
Ulcerative Colitis	0.7	1.0	2.4	1.1	1.1	0.7	1.0	-1.6	1.0	1.2	0.2	1.4	0.0	1.1	1.0	-0.9	-0.6	-1.0	-0.9	1.2	1.2	-0.8	1.1	-0.7
Blood Eosinophil Count	0.1	0.9	6.2	-0.6	-1.0	-1.6	-0.8	0.4	-1.0	-0.8	-0.5	-0.4	-2.5	-0.5	-0.8	0.4	1.1	0.9	0.6	-1.0	-0.2	1.1	-0.7	0.8
Blood Platelet Count	0.0	0.4	1.2	0.6	0.4	0.6	0.5	-0.5	0.8	0.6	0.8	0.8	-1.0	1.1	0.5	-0.9	-0.3	-0.2	0.1	0.5	0.3	0.4	0.6	-0.5
Blood Red Count	0.1	1.3	4.2	1.4	1.1	1.0	1.2	-1.0	1.1	1.3	0.7	0.8	-0.6	1.1	1.3	-2.1	-0.9	-1.2	-0.2	1.1	1.2	-1.0	1.3	-1.5
Blood White Count	0.0	0.3	3.5	0.0	-0.2	0.2	0.1	-0.7	-0.1	0.3	0.2	0.5	-1.9	0.1	0.0	-0.2	-0.3	0.4	-0.8	-0.2	0.3	-0.7	0.1	0.4
Heel T-Score	0.2	1.6	4.5	1.3	1.2	1.4	1.2	-1.5	1.5	1.3	1.0	1.4	0.3	1.7	1.3	-0.7	0.1	-1.3	-1.3	1.3	2.1	0.0	1.3	-0.8
BMI	0.2	1.2	6.4	1.0	1.0	0.5	0.9	-0.7	0.6	1.0	1.1	0.3	-1.0	1.6	1.1	-0.7	0.9	-0.8	-1.7	0.8	2.5	0.7	1.0	-0.4
Height	0.0	0.4	2.6	0.0	-0.1	-0.1	-0.2	-0.8	0.1	-0.2	-1.6	-1.4	1.0	-0.1	-0.4	0.3	-0.2	0.0	0.9	-0.1	-0.7	0.0	-0.1	-0.3
Waist Hip Ratio (WHR)	0.7	3.1	5.2	-1.8	-1.8	-1.6	-2.3	1.8	-1.7	-1.9	-1.9	-2.0	-0.1	-2.0	-2.0	1.7	1.0	1.7	2.1	-1.8	-2.0	1.0	-1.8	1.4
Systolic Blood Pressure	0.3	1.5	3.8	-1.2	-1.3	-1.9	-1.5	1.1	-1.5	-1.1	-0.5	-0.3	0.3	-1.1	-1.3	0.7	1.2	1.2	1.4	-1.2	-1.4	1.3	-1.2	1.5
Smoking Status	0.8	2.0	4.0	-1.8	-1.7	-1.9	-1.1	0.6	-1.7	-1.6	-1.5	-0.3	-1.1	-1.7	-1.7	1.1	0.5	1.6	1.2	-1.6	-2.0	0.4	-1.6	1.3
Allergy or Eczema	0.9	2.4	4.9	-1.6	-1.5	-1.5	-1.5	1.2	-1.8	-1.5	-2.1	-1.1	-0.0	-1.9	-1.7	1.2	1.1	1.5	1.9	-1.5	-2.2	1.2	-1.6	1.3
Cardiovascular Disease	0.9	2.8	7.5	-1.6	-1.8	-2.3	-1.8	1.6	-1.4	-1.7	-0.9	-1.2	-0.3	-0.7	-1.5	1.2	2.6	1.7	1.8	-1.8	-1.1	2.7	-1.6	2.0
Hypothyroidism (self reported)	0.9	2.0	7.7	1.3	1.7	1.2	1.8	-1.6	1.1	1.2	1.1	0.7	-0.0	0.4	1.2	-1.6	-1.9	-1.3	-1.2	1.4	0.9	-2.8	1.2	-1.5
Respiratory disease	0.9	1.9	3.7	-1.3	-1.4	-1.0	-1.4	1.4	-1.9	-1.2	-0.9	-1.4	-1.3	-1.9	-1.3	1.4	1.7	1.4	0.8	-1.4	-1.1	0.5	-1.5	1.8
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.6	0.0	-0.2	-0.5	0.2	0.7	0.0	-0.0	-0.2	-0.4	-1.3	0.4	0.1	-0.4	0.6	0.1	0.4	-0.1	0.2	0.3	-0.1	0.3
Lung FEV1/FVC ratio	3.8	19.5	27.9	4.6	4.7	5.3	4.9	-4.5	4.8	4.6	3.1	4.0	0.4	4.2	5.2	-4.4	-3.6	-4.8	-4.1	4.6	5.0	-4.0	4.8	-4.7
Lung FVC	0.1	0.6	3.5	0.3	-0.1	0.1	0.8	-1.9	0.5	0.3	-1.1	1.7	-0.2	-0.1	0.4	-1.2	-1.1	-0.2	0.6	0.4	-0.9	-0.7	0.4	-0.5
Neuroticism	0.1	0.3	1.9	0.5	0.6	0.7	0.5	-0.6	0.4	0.5	0.7	0.2	0.2	0.3	0.4	-0.1	-1.4	-0.5	-0.5	0.4	0.0	-0.9	0.5	-0.5
Chronotype (morning person)	0.1	0.3	2.5	0.1	-0.0	0.3	-0.2	1.2	-0.0	-0.2	-0.7	-1.6	-0.3	0.3	0.0	0.4	0.7	-0.1	0.4	0.1	0.4	0.7	-0.0	0.0
Hair Pigment	0.0	0.3	0.7	0.5	0.5	0.3	0.4	-0.2	0.7	0.6	0.3	0.6	-0.1	0.8	0.4	-0.7	-0.3	-0.5	0.4	0.6	0.3	0.4	0.6	-0.5
Tanning	0.1	1.3	4.2	1.3	1.0	1.6	0.9	-1.6	1.1	1.0	0.4	2.0	0.4	0.9	1.2	-1.0	-1.1	-1.1	-0.7	1.1	0.6	-1.2	1.1	-0.9
Hand grip strength (left)	0.8	2.2	4.5	-1.5	-1.4	-1.9	-1.7	1.3	-1.4	-1.4	-1.6	-0.8	1.6	-1.2	-1.2	1.8	0.9	1.5	1.4	-1.3	-2.1	1.1	-1.4	1.8
Number of treatments/medications taken	0.3	0.5	1.6	-0.5	-0.6	-0.7	-0.3	0.8	-0.3	-0.7	0.2	-0.4	1.3	0.1	-0.4	-0.2	0.9	0.6	1.1	-0.6	-0.6	1.1	-0.6	0.7
Average weekly spirits intake	1.5	1.9	3.9	-1.6	-1.4	-1.5	-1.5	1.0	-1.7	-1.3	-1.0	-0.1	-0.6	-1.9	-1.3	1.1	1.2	1.5	1.2	-1.5	-1.8	0.4	-1.4	2.0
Sensitivity / hurt feelings	0.3	0.4	2.2	0.4	0.6	0.3	0.6	-0.8	0.1	0.3	0.3	-0.7	-1.5	0.2	0.1	-0.1	-1.4	-0.3	-1.0	0.2	0.0	-1.0	0.4	-0.5
Frequency of depressed mood in last 2 weeks	0.2	0.2	2.8	-0.3	-0.1	-0.2	-0.3	0.3	-0.5	-0.3	-0.0	-1.7	-0.1	-0.6	-0.4	0.3	-0.1	0.2	-0.1	-0.3	-0.4	-0.4	-0.3	0.2
Hearing difficulty/problems: Yes	1.2	1.9	8.8	-1.4	-1.3	-1.7	-1.4	0.7	-1.2	-1.3	-1.7	-3.0	-0.4	-1.3	-1.5	1.3	1.0	1.1	1.1	-1.2	-1.4	0.6	-1.3	1.0
Relative age of first facial hair	5.0	10.4	16.7	-3.6	-3.5	-4.1	-3.0	2.4	-3.9	-3.5	-3.0	-3.1	1.0	-4.1	-3.5	2.4	2.2	3.4	2.8	-3.5	-4.1	1.5	-3.5	3.4
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	1.0	0.3	0.4	1.0	0.1	-0.2	0.4	0.3	0.6	-0.1	0.8	0.5	0.2	-0.1	-0.2	-0.4	-0.1	0.4	0.2	0.8	0.2	-0.7
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.8	-0.9	-0.9	-0.9	-0.9	0.5	-1.1	-0.9	-1.7	-0.3	-0.5	-0.6	-1.0	0.8	1.2	0.9	1.2	-1.0	-0.8	1.5	-1.0	0.9
Ever had hysterectomy (womb removed)	0.4	0.4	1.1	0.6	0.5	0.6	0.3	-0.9	0.9	0.6	0.1	-0.1	-0.7	0.6	0.5	-0.0	-1.0	-0.7	-0.8	0.8	0.5	-0.9	0.6	-0.8
Systolic blood pressure, automated reading	0.0	0.1	0.4	0.2	0.1	-0.5	-0.1	0.0	-0.1	0.1	0.4	0.0	0.0	0.1	-0.2	-0.2	-0.3	-0.1	-0.6	0.0	0.3	-0.6	0.1	-0.1
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.8	0.4	0.4	0.5	0.5	0.3	0.4	0.3	0.3	-0.6	-1.3	0.6	0.4	-0.7	0.4	-0.5	0.1	0.3	0.9	-0.0	0.4	-0.5
Angina	0.4	0.5	2.1	-0.8	-0.3	-0.3	-0.6	1.4	-0.7	-0.8	-0.7	-0.7	0.6	-0.4	-0.6	0.8	0.8	0.6	0.8	-0.5	-0.5	1.0	-0.7	0.7
Medication for hormone replacement therapy	1.0	1.1	3.7	0.8	0.9	1.4	0.9	-1.2	0.8	0.8	0.6	1.9	0.5	0.8	0.9	-0.4	-1.1	-1.0	-1.5	1.0	1.0	-1.9	0.8	-0.2
Vitamin and mineral supplements	0.6	0.8	1.6	-1.0	-0.9	-0.8	-0.7	0.7	-1.1	-1.0	-1.0	-0.9	-0.4	-1.3	-0.9	1.2	0.7	0.9	0.4	-0.9	-0.8	-0.4	-1.1	1.0
Supplements: Zinc	1.6	1.7	3.6	1.3	1.4	1.6	1.1	-1.6	1.3	1.2	0.3	0.0	0.6	0.7	1.2	-1.1	-1.8	-1.4	-1.8	1.4	1.4	-1.9	1.3	-1.2
Medication: Co-codamol	0.3	0.4	1.3	-0.5	-0.4	-0.8	-0.4	-0.4	-0.3	-0.6	-1.1	-0.6	0.8	-0.1	-0.6	-0.1	0.6	0.4	0.5	-0.5	-0.6	1.1	-0.5	0.4
Medication: Metformin	0.9	1.3	2.4	1.4	1.2	1.1	1.5	-0.2	1.3	1.3	0.7	0.5	-0.2	1.5	1.3	-1.1	-1.0	-1.3	-0.7	1.2	1.3	-0.8	1.2	-1.2
Diabetes (father)	0.7	0.9	1.9	1.0	1.0	1.2	0.8	-0.1	1.0	0.8	1.0	1.3	-0.7	1.3	1.1	-0.4	-0.6	-0.9	-1.2	1.0	1.4	-0.3	0.9	-0.8
Diabetes (mother)	0.3	0.4	1.6	0.5	0.6	0.5	0.2	0.0	0.5	0.4	1.1	0.4	-0.6	0.4	0.6	-0.9	-0.7	-0.7	-0.4	0.5	0.7	-1.2	0.6	-0.8
Severe depression (siblings)	0.3	0.3	1.0	0.3	0.6	1.0	0.4	-0.6	0.7	0.5	0.7	0.7	-0.1	0.3	0.6	-0.1	-0.8	-0.5	-0.2	0.6	0.3	-0.6	0.5	-0.9
Pack years adult smoking proportion	1.8	2.8	4.8	-1.9	-1.9	-1.6	-1.6	1.5	-1.7	-1.6	-1.3	0.5	-0.1	-1.4	-1.9	1.4	1.8	1.9	2.1	-1.8	-1.9	2.2	-1.8	1.8
Impedance of leg (right)	0.1	0.3	1.4	-0.3	-0.5	-0.7	-0.3	0.1	-0.1	-0.4	-0.0	0.5	1.1	-0.1	-0.5	-0.2	-0.6	0.4	0.8	-0.4	-1.2	0.4	-0.4	0.0
Leg fat-free mass (left)	0.1	0.3	1.0	0.7	0.8	0.3	0.4	-0.5	0.3	0.7	-0.1	-0.1	-0.6	0.4	0.5	-0.4	-0.1	-0.8	-0.8	0.7	1.0	-0.4	0.7	-0.8
Trunk fat percentage	1.0	3.8	6.9	2.1	2.3	1.2	2.3	-1.4	1.7	2.0	1.8	2.0	-0.8	2.0	2.2	-2.6	-1.1	-2.2	-2.0	2.2	2.6	-0.8	2.2	-2.0
Hand grip strength (right)	0.4	1.0	2.3	-0.9	-0.9	-1.1	-1.0	0.2	-1.0	-0.9	-1.5	0.4	1.2	-1.1	-0.7	1.2	0.5	0.9	1.0	-0.8	-1.5	0.3	-0.8	1.3
Townsend deprivation index at recruitment	6.7	9.5	13.8	-3.3	-3.4	-3.7	-3.4	3.3	-3.5	-3.2	-2.9	-2.6	0.2	-3.1	-3.5	2.7	2.8	3.3	2.8	-3.3	-3.3	2.4	-3.3	3.0
Current tobacco smoking	3.8	6.2	9.5	-2.9	-2.7	-2.9	-2.4	2.2	-2.6	-2.6	-3.1	-0.4	-0.2	-2.6	-2.9	2.7	2.1	2.7	2.5	-2.6	-2.7	2.3	-2.6	2.3
Average weekly fortified wine intake	0.9	1.1	2.2	1.0	1.0	1.0	1.0	-1.3	1.1	1.2	1.5	0.4	-1.1	1.3	1.0	-0.7	-0.9	-0.9	-1.0	1.0	1.0	-0.8	1.1	-0.7
Maternal smoking around birth	4.9	7.1	10.9	-2.8	-2.9	-3.3	-2.6	1.8	-3.0	-2.7	-2.8	-1.5	-1.1	-3.2	-3.0	1.7	2.8	2.9	3.0	-2.7	-3.0	2.3	-2.8	2.8
Fed-up feelings	0.9	1.7	3.3	-1.4	-1.3	-1.6	-1.3	0.8	-1.8	-1.5	-0.9	-1.2	-0.7	-1.6	-1.6	1.0	0.5	1.5	0.7	-1.6	-1.6	0.4	-1.5	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.6	-0.7	-0.4	-0.7	-0.5	-0.3	-0.5	-0.7	-0.6	-1.2	1.0	-0.8	-0.6	0.4	0.1	0.6	0.8	-0.4	-1.2	0.7	-0.6	0.4
Relative age voice broke	2.6	4.0	7.7	-2.2	-2.3	-2.0	-2.0	1.6	-2.2	-2.2	-1.7	-2.0	1.1	-2.7	-2.2	1.6	1.1	2.0	2.2	-2.0	-2.8	0.9	-2.2	1.5
Taking other prescription medications	0.2	0.4	4.0	-0.3	-0.2	-0.2	-0.3	0.1	-0.3	-0.4	0.4	-0.2	2.0	-0.2	-0.4	-0.3	0.6	0.1	1.1	-0.3	-0.5	0.3	-0.4	0.4
Age when periods started (menarche)	0.2	0.6	1.6	-0.7	-1.0	-1.2	-0.6	0.5	-0.6	-0.9	-0.9	-0.3	-0.4	-0.7	-0.6	0.4	0.1	1.0	0.8	-0.9	-1.3	0.4	-0.8	0.4
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.6	1.1	0.8	0.8	1.1	-1.1	0.9	1.0	-0.3	1.6	0.4	0.7	1.0	-0.9	-0.7	-1.0	-0.1	1.1	0.4	-0.4	1.0	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	3.8	-0.0	0.1	0.3	0.2	0.3	0.1	0.1	0.6	-0.8	1.9	0.2	-0.1	-0.0	0.2	-0.2	-0.0	0.3	0.3	0.6	0.1	0.0
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.7	-0.1	-0.2	-0.5	0.1	-0.1	-0.1	-0.2	-0.6	0.1	-1.3	0.0	-0.0	0.1	-1.1	0.1	0.1	-0.2	-0.9	-0.5	-0.2	-0.1
Qualifications: CSEs or equivalent	2.1	2.7	4.6	-1.8	-1.5	-2.1	-1.8	1.4	-1.8	-1.9	-0.8	-0.6	0.8	-1.7	-2.0	1.2	1.6	1.8	1.7	-1.8	-2.1	1.6	-1.9	1.7
Serious illness, injury or assault to yourself	0.3	0.3	3.2	-0.2	-0.2	0.1	-0.3	0.3	-0.2	-0.3	-0.8	-1.8	0.5	-0.4	-0.2	0.8	0.7	0.2	0.6	-0.1	0.1	0.4	-0.3	0.1
High blood pressure	0.2	0.6	2.5	0.9	0.7	0.6	0.6	-0.6	0.9	0.7	0.8	0.6	-0.2	1.6	1.0	-1.2	0.2	-0.8	-0.5	0.8	1.1	0.4	0.9	-0.6
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.3	-0.6	-0.7	-0.9	-0.4	0.2	-0.9	-0.6	-0.4	0.1	-1.1	-0.9	-0.6	0.2	0.2	0.6	1.1	-0.6	-1.5	0.3	-0.6	0.5
Multivitamins +/- minerals	0.1	0.1	0.6	0.1	0.1	0.0	0.1	-0.1	0.2	0.1	0.5	0.8	-0.0	0.2	0.1	-0.7	-0.3	0.1	0.3	0.1	-0.1	0.5	0.2	-0.5
Stomach or abdominal pain in last month	0.4	0.5	2.0	-0.8	-0.5	-1.2	-0.3	0.1	-0.6	-0.8	-0.4	-0.4	1.4	-0.8	-0.7	0.6	0.7	0.6	0.7	-0.6	-0.4	0.5	-0.7	0.9
Supplements: Glucosamine	0.3	0.4	4.8	0.2	0.5	0.6	0.1	-1.0	0.5	-0.1	-0.9	0.3	2.2	-0.1	0.1	0.5	-0.1	-0.4	-0.1	0.3	0.2	0.1	0.1	-0.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.8	-0.9	-0.8	-1.3	-0.7	0.9	-0.7	-0.8	-1.2	-0.3	-0.5	-0.7	-0.9	0.8	0.9	0.9	0.5	-0.9	-0.7	1.0	-0.8	1.0
Medication: Atenolol	1.9	2.3	4.7	1.7	1.6	1.8	1.8	-0.6	1.8	1.6	1.9	-0.2	-1.0	2.2	1.9	-2.0	-0.6	-1.5	-1.1	1.7	1.6	-0.5	1.6	-1.4
Medication: Levothyroxine sodium	1.2	2.0	4.9	1.3	1.7	1.2	2.0	-1.2	1.3	1.3	1.6	1.1	0.3	1.0	1.2	-1.6	-1.7	-1.5	-1.5	1.4	1.3	-2.2	1.2	-1.4
Sitting height	0.2	1.3	2.5	-1.0	-1.1	-1.4	-1.6	0.3	-1.4	-0.9	-1.3	-0.9	-0.4	-1.2	-1.3	0.9	1.2	1.0	1.4	-0.9	-1.3	1.3	-0.9	0.9
Chronic bronchitis/emphysema (father)	1.5	1.8	4.8	-1.4	-1.1	-0.9	-1.2	1.4	-1.3	-1.2	-1.6	-2.2	1.5	-1.5	-1.3	1.5	1.2	1.3	1.1	-1.2	-1.0	0.9	-1.2	1.3
High blood pressure (mother)	0.1	0.2	0.6	0.5	0.2	0.7	0.3	-0.1	0.6	0.4	-0.1	-0.2	-0.2	0.4	0.5	-0.5	-0.5	-0.4	-0.2	0.3	0.2	-0.8	0.4	-0.5
Body mass index (BMI)	0.4	1.9	5.5	1.4	1.7	0.8	1.5	-1.2	1.1	1.5	1.2	0.6	-0.9	1.5	1.5	-1.3	-0.3	-1.5	-1.9	1.5	2.3	-0.5	1.5	-1.2
Impedance of leg (left)	0.1	0.3	1.3	-0.3	-0.5	-0.8	-0.4	0.1	-0.2	-0.5	-0.1	0.5	1.1	-0.1	-0.5	-0.1	-0.3	0.5	0.8	-0.5	-1.1	0.5	-0.4	0.2
Leg predicted mass (left)	0.1	0.3	1.0	0.6	0.8	0.3	0.3	-0.5	0.3	0.7	-0.1	-0.1	-0.5	0.3	0.5	-0.3	-0.1	-0.8	-0.8	0.7	1.0	-0.5	0.7	-0.7
Trunk fat mass	0.7	3.1	6.3	1.9	2.1	1.1	2.0	-1.4	1.6	1.9	1.8	1.4	-0.5	1.9	2.0	-2.2	-0.9	-2.0	-1.9	2.0	2.5	-0.6	2.0	-1.9
Waist circumference	0.2	0.6	2.9	0.8	1.1	0.3	0.6	-0.3	0.6	0.8	1.0	0.1	0.1	0.7	0.8	-0.7	0.1	-0.9	-1.2	0.9	1.7	0.1	0.9	-0.9
Number of incorrect matches in round	0.1	0.2	0.9	-0.3	-0.1	-0.4	-0.7	0.6	-0.2	-0.5	0.0	-1.0	0.8	-0.3	-0.8	0.3	-0.4	0.1	-0.2	-0.3	-0.4	-0.1	-0.4	0.2
Past tobacco smoking	0.1	0.2	0.9	-0.0	-0.3	-0.0	-0.9	0.6	-0.0	-0.1	-1.0	-0.2	0.5	-0.3	-0.2	0.7	0.3	0.3	0.5	-0.2	-0.1	0.1	-0.2	0.3
Alcohol usually taken with meals	5.3	8.6	11.9	3.1	3.1	3.2	2.6	-2.9	3.0	3.0	3.4	3.2	1.3	2.6	3.0	-2.6	-3.3	-3.0	-2.8	3.2	2.7	-2.4	3.0	-3.4
Nervous feelings	0.1	0.1	1.2	0.1	0.2	0.2	0.1	0.2	-0.0	0.1	0.8	-1.1	0.1	-0.1	-0.2	-0.1	-0.5	-0.1	-0.2	0.1	-0.1	-0.3	0.1	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	2.9	-1.3	-1.0	-1.2	-1.3	0.7	-1.3	-1.1	-1.1	-1.1	0.4	-1.7	-1.2	1.4	-0.1	1.0	0.5	-1.1	-1.5	-0.6	-1.2	1.4
Hearing difficulty/problems with background noise	1.5	2.5	4.0	-1.7	-1.5	-2.0	-1.8	1.3	-1.6	-1.7	-1.9	-1.7	-0.9	-1.6	-1.9	1.8	0.8	1.5	1.7	-1.5	-2.0	0.8	-1.6	1.2
Hair/balding pattern: Pattern 2	1.6	2.1	3.7	-1.2	-1.4	-1.6	-1.3	1.3	-1.8	-1.4	-1.9	-1.2	-1.4	-1.2	-1.2	0.9	1.9	1.3	1.2	-1.4	-1.3	1.4	-1.4	1.8
Had menopause	0.1	0.1	0.4	0.2	0.2	0.2	0.2	0.7	-0.1	0.1	-0.5	0.2	-0.5	-0.0	0.1	-0.3	0.3	-0.1	0.2	0.1	0.4	0.1	0.2	-0.3
Had other major operations	1.0	1.2	3.0	1.0	1.0	1.4	0.8	-1.6	1.1	1.1	0.6	1.7	-1.2	0.6	0.9	-1.2	-1.4	-1.0	-0.5	1.0	0.3	-1.5	1.0	-1.2
Forced vital capacity (FVC)	0.2	0.6	2.5	-0.5	-0.8	-0.6	-0.5	-0.4	-0.5	-0.6	-1.6	-0.7	0.8	-0.7	-0.6	0.2	0.2	0.6	1.3	-0.6	-1.6	-0.1	-0.6	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	3.1	-1.1	-0.9	-0.7	-0.8	0.9	-1.0	-0.9	-0.2	-1.7	1.8	-0.9	-1.2	0.7	1.0	0.7	0.5	-0.7	-0.6	1.4	-1.0	1.0
Ever unenthusiastic/disinterested for a whole week	1.2	1.5	2.1	-1.3	-1.2	-1.2	-1.3	0.9	-1.4	-1.2	-1.4	-1.1	-0.8	-1.5	-1.3	1.1	1.1	1.2	1.3	-1.3	-1.5	0.9	-1.3	1.3
Qualifications: None of the above	0.3	0.6	1.7	0.9	0.8	0.1	0.7	-0.8	0.8	0.7	0.7	0.2	0.0	1.3	0.7	-0.9	-0.5	-0.9	-1.0	0.8	1.1	0.1	0.8	-0.4
Financial difficulties in last 2 years	1.1	1.4	2.6	-1.3	-1.3	-1.4	-1.0	1.4	-1.3	-1.4	-0.7	-0.8	-1.6	-0.8	-1.2	0.4	0.9	1.3	0.7	-1.4	-1.3	1.4	-1.3	1.1
Mouth/teeth dental problems	0.1	0.1	0.5	0.0	0.0	0.4	-0.2	0.0	-0.3	0.0	-0.4	0.4	0.3	-0.6	0.2	0.6	-0.0	-0.2	0.0	-0.1	-0.2	-0.7	0.0	0.1
Heart attack	0.3	0.3	1.9	-0.1	-0.1	-0.5	0.5	0.6	-0.1	-0.2	-0.3	0.1	-0.4	0.1	-0.1	-0.9	1.3	0.2	1.4	-0.2	0.2	1.1	-0.1	-0.0
Allergy	0.5	1.2	2.8	1.2	1.1	1.1	0.9	-1.1	1.6	1.2	0.6	0.3	0.9	1.5	1.0	-0.9	-0.7	-1.2	-1.1	1.2	1.7	-0.6	1.2	-1.1
Pain all over the body in last month	3.8	4.1	7.5	-2.2	-2.1	-2.1	-2.2	2.4	-1.7	-1.9	-2.1	-1.2	-0.5	-2.2	-2.0	2.0	1.7	2.1	2.6	-2.1	-2.7	1.2	-2.0	2.1
Diabetes (self-reported)	0.1	0.2	1.4	-0.4	-0.4	-0.6	-0.1	1.2	-0.3	-0.4	-0.0	-0.8	-0.2	-0.1	-0.0	-0.1	0.7	0.3	0.4	-0.5	-0.2	0.2	-0.3	0.7
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.4	-0.2	-0.2	-0.6	-0.1	0.3	-0.4	-0.2	-0.1	-0.0	-0.0	0.1	-0.5	-0.2	0.0	0.1	0.0	-0.2	-0.6	0.2	-0.2	0.3
Medication: Ramipril	0.3	0.3	1.4	-0.6	-0.2	-0.2	-0.2	1.1	-0.6	-0.4	0.3	-0.9	0.9	-0.1	-0.4	0.2	1.0	0.3	-0.0	-0.3	0.3	1.2	-0.4	0.5
Medication: Simvastatin	0.2	0.3	1.5	0.2	0.3	0.3	0.5	-0.1	0.3	0.3	0.8	0.9	-1.0	0.5	0.5	-1.2	0.4	-0.2	-0.2	0.2	0.6	0.8	0.3	-0.0
Fluid intelligence score	0.1	0.3	2.0	0.4	0.3	0.8	0.4	-0.3	0.6	0.4	0.3	0.2	1.4	0.9	0.6	0.6	-0.3	-0.4	-0.1	0.5	0.3	0.2	0.5	-0.4
Illnesses of siblings	0.3	0.4	2.4	0.5	0.4	0.3	0.4	-0.9	0.8	0.6	0.4	0.9	-1.1	0.5	0.4	-0.4	-1.5	-0.1	-0.5	0.4	-0.1	-0.5	0.6	-0.7
Neuroticism score	0.2	0.3	1.0	-0.5	-0.3	-0.4	-0.5	0.2	-0.6	-0.5	-0.1	-1.0	0.6	-0.7	-0.7	0.7	-0.6	0.4	0.2	-0.5	-0.9	-0.5	-0.6	0.5
Weight	0.3	1.3	3.8	1.2	1.5	0.6	1.1	-1.1	0.8	1.3	0.8	0.4	-0.5	1.1	1.1	-1.1	-0.2	-1.4	-1.4	1.3	2.0	-0.4	1.3	-1.2
Impedance of arm (right)	0.1	0.5	2.6	0.4	0.4	0.3	0.9	-0.3	0.7	0.4	0.1	1.6	0.2	0.4	0.7	-1.4	-1.0	-0.5	0.0	0.5	-0.0	-0.2	0.5	-0.8
Arm fat percentage (right)	1.3	5.1	9.5	2.3	2.6	1.6	2.7	-1.9	2.1	2.4	1.8	2.1	-0.8	2.2	2.7	-2.7	-1.4	-2.5	-2.5	2.5	3.1	-1.3	2.5	-2.3
Trunk fat-free mass	0.0	0.2	1.3	-0.0	0.2	-0.2	-0.5	-0.3	-0.3	0.1	-0.6	-1.1	0.4	-0.2	-0.3	0.9	0.2	-0.1	-0.3	-0.0	0.2	-0.3	-0.0	0.1
Hip circumference	0.7	3.2	8.2	1.9	2.1	1.4	1.8	-1.4	1.6	1.9	2.0	0.8	-0.5	1.8	1.8	-1.8	-0.8	-1.9	-2.4	1.9	2.9	-0.9	2.0	-1.9
Time employed in main current job	2.1	2.5	4.9	-1.6	-1.5	-1.5	-1.4	1.4	-1.4	-1.6	-0.7	-1.9	0.3	-1.4	-1.4	1.2	2.2	1.8	1.7	-1.6	-1.3	2.0	-1.7	2.0
Alcohol intake versus 10 years previously	0.2	0.2	2.1	0.2	0.3	0.1	0.2	-0.5	0.4	0.2	-1.4	-1.1	0.3	0.5	0.1	0.3	0.3	-0.3	0.3	0.1	0.4	-0.0	0.1	0.2
Father’s age at death	2.7	3.6	6.2	1.9	2.2	2.5	1.9	-2.1	2.1	2.0	1.5	0.1	2.3	1.6	1.9	-1.4	-1.0	-2.1	-1.5	2.1	2.3	-1.4	2.1	-2.4
Worrier / anxious feelings	0.1	0.3	0.8	-0.5	-0.4	-0.5	-0.5	0.2	-0.5	-0.4	0.8	-0.6	0.9	-0.3	-0.4	0.7	-0.2	0.3	-0.3	-0.5	-0.6	-0.2	-0.4	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.7	-0.3	-0.3	-0.7	-0.3	0.5	-0.3	-0.2	0.2	-0.8	-0.5	-0.1	-0.5	0.0	0.1	0.2	0.6	-0.3	-0.5	0.2	-0.2	0.3
Falls in the last year	0.7	1.0	2.8	1.1	1.1	0.9	0.8	-0.4	1.3	1.0	1.6	0.1	-0.7	1.7	0.7	-1.1	-0.5	-0.9	-0.9	1.1	1.2	-0.0	1.0	-0.4
Hair/balding pattern: Pattern 3	0.3	0.4	1.2	0.5	0.8	1.1	0.3	-0.6	0.6	0.5	0.8	-0.4	0.6	1.0	0.5	0.2	0.1	-0.6	-0.4	0.6	1.0	0.6	0.4	-0.6
Number of live births	0.1	0.2	1.1	0.2	0.2	-0.0	0.0	-0.4	-0.2	-0.0	-0.5	-0.5	0.6	0.3	-0.0	0.2	0.5	-0.1	-0.3	0.0	1.1	0.8	0.1	-0.2
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	3.8	1.2	1.0	1.4	1.2	-1.9	1.2	1.2	-0.2	0.7	0.6	1.0	1.2	-1.5	-1.1	-1.2	-0.2	1.2	0.3	-1.6	1.1	-0.9
Pulse rate	0.4	0.7	1.6	-0.9	-0.8	-1.3	-0.9	0.3	-0.9	-1.0	-0.7	-1.1	0.4	-1.1	-1.0	1.1	0.3	0.7	0.7	-0.8	-1.2	-0.1	-0.8	0.7
Happiness	0.5	0.5	1.5	0.8	0.9	0.4	0.8	-0.8	0.7	0.8	-0.0	0.3	0.1	0.5	0.7	-1.1	-1.2	-0.8	-0.5	0.9	0.2	-0.3	0.9	-1.2
Noisy workplace	2.1	2.6	7.1	-1.7	-1.5	-1.6	-1.3	1.6	-1.6	-1.6	-1.5	-2.7	0.0	-0.9	-1.7	1.4	1.8	1.7	1.5	-1.6	-1.5	2.0	-1.6	1.7
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.8	0.9	0.7	0.8	0.8	-1.0	0.7	1.0	0.4	1.3	0.4	0.5	0.7	-1.2	-0.9	-0.8	-0.7	0.8	0.5	-0.6	0.8	-0.8
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	4.1	-1.3	-1.5	-0.7	-1.0	1.2	-1.0	-1.2	-0.9	0.7	0.0	-1.0	-1.2	0.4	2.0	1.3	1.6	-1.3	-1.0	1.6	-1.3	1.3
Mouth/teeth dental problems: Dentures	0.1	0.2	1.4	-0.3	-0.2	-0.2	0.4	0.7	0.1	-0.2	0.5	0.1	0.2	0.3	-0.1	-0.2	0.6	0.3	-0.2	-0.1	0.8	1.2	-0.2	0.3
Asthma	0.1	0.1	0.4	-0.2	-0.2	0.2	-0.2	0.5	-0.4	-0.1	0.3	0.4	-0.4	-0.6	-0.0	0.6	0.3	0.1	0.3	-0.2	-0.2	-0.6	-0.3	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.2	1.1	1.0	1.0	1.0	-1.2	1.2	1.1	1.1	1.0	0.4	1.3	0.9	-1.5	-0.5	-0.9	0.1	1.1	0.6	-0.2	1.0	-0.8
Medication: Cholesterol lowering	0.2	0.3	2.1	0.1	0.2	0.1	0.6	-0.4	0.2	0.1	0.6	1.5	0.2	0.5	0.8	-1.0	0.3	-0.4	0.1	0.3	0.3	0.8	0.3	-0.1
Depression (self-reported)	0.3	0.4	1.8	-0.6	-0.3	-0.6	-0.1	0.5	-1.0	-0.7	-0.4	-0.4	-0.1	-0.9	-0.8	0.1	-0.5	0.6	0.7	-0.6	-1.3	-0.1	-0.7	0.2
Medication: Lansoprazole	0.2	0.2	1.4	-0.1	-0.2	-0.4	-0.1	1.2	-0.2	-0.2	0.0	-0.3	-1.1	0.1	-0.0	-0.4	0.1	0.0	0.5	-0.1	-0.6	0.3	-0.2	0.1
Prospective memory result	1.6	2.0	3.5	1.4	1.4	1.6	1.0	-1.3	1.6	1.3	1.9	1.4	0.1	1.3	1.2	-1.1	-1.7	-1.4	-1.2	1.3	1.4	-1.8	1.3	-1.8
Lung cancer (father)	2.7	3.2	7.3	-1.7	-1.8	-1.8	-1.9	1.2	-1.8	-1.5	-2.7	-2.0	0.3	-1.7	-1.7	1.8	1.6	1.8	1.9	-1.6	-2.1	1.9	-1.7	1.8
Illnesses of mother	0.1	0.2	1.8	-0.1	0.3	0.5	0.1	-0.3	-0.0	0.2	-0.4	-0.0	1.3	-0.2	-0.1	0.8	-0.2	-0.2	-0.2	0.1	-0.1	-0.4	0.0	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	6.7	2.1	1.8	2.0	1.8	-2.6	1.9	2.0	0.6	1.3	0.6	1.4	1.8	-2.2	-2.0	-2.1	-1.1	2.1	1.1	-2.6	2.0	-1.9
Pulse wave Arterial Stiffness index	2.4	2.8	4.6	-1.8	-1.8	-1.7	-1.5	1.3	-1.9	-1.6	-1.9	-1.5	0.7	-2.0	-1.9	1.0	2.1	1.8	1.8	-1.8	-1.3	1.8	-1.7	1.5
Impedance of arm (left)	0.2	1.0	3.6	0.9	0.8	0.8	1.3	-0.4	1.1	0.7	0.5	1.9	0.4	0.8	1.2	-1.8	-1.3	-0.9	-0.3	0.9	0.2	-0.5	0.9	-1.2
Arm fat mass (right)	0.6	2.4	5.7	1.6	1.9	1.0	1.8	-1.2	1.3	1.7	1.3	1.0	-0.8	1.6	1.8	-1.7	-0.7	-1.7	-1.9	1.7	2.4	-0.7	1.8	-1.6
Trunk predicted mass	0.0	0.2	1.2	-0.1	0.1	-0.2	-0.6	-0.3	-0.3	-0.0	-0.6	-1.1	0.4	-0.3	-0.4	0.9	0.3	0.0	-0.2	-0.1	0.2	-0.3	-0.1	0.2
Standing height	0.0	0.1	0.4	0.0	0.1	-0.1	-0.6	-0.2	-0.1	-0.1	-0.5	-0.3	0.6	-0.2	-0.4	0.4	0.1	-0.1	0.5	0.0	-0.2	0.3	-0.0	-0.2
Length of working week for main job	1.2	1.3	7.7	-1.0	-1.1	-1.6	-0.7	0.3	-0.9	-0.9	-1.2	-2.0	-2.8	-0.5	-0.7	0.8	0.3	1.0	0.2	-1.0	-1.3	0.5	-1.0	1.0
Exposure to tobacco smoke at home	1.2	1.3	4.3	-1.2	-1.2	-1.0	-1.1	1.0	-1.1	-1.1	-1.0	-2.1	-1.3	-1.0	-1.0	0.8	1.2	1.2	0.6	-1.1	-1.0	0.7	-1.1	1.5
Breastfed as a baby	1.0	1.2	2.3	1.2	1.2	1.5	1.5	-0.9	1.2	1.1	1.0	0.1	-0.6	1.1	1.3	-0.7	-1.3	-1.3	-0.7	1.2	0.7	-1.1	1.2	-1.5
Tense / ‘highly strung’	0.3	0.4	2.1	-0.6	-0.5	-0.6	-0.9	0.8	-0.4	-0.5	0.3	-0.7	-0.3	-0.4	-0.7	0.8	-0.5	0.5	0.8	-0.5	-1.4	-0.2	-0.5	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.8	-0.6	-0.3	-0.4	-0.6	-0.2	-0.6	-0.5	-0.5	-0.1	1.3	-1.0	-0.7	0.4	-1.0	0.2	0.4	-0.3	-1.1	-0.9	-0.5	0.0
Hair/balding pattern: Pattern 4	2.0	4.8	11.3	2.0	2.2	2.1	2.4	-1.3	2.7	2.1	3.4	2.3	1.7	2.3	2.2	-1.9	-2.0	-2.2	-2.2	2.3	2.0	-1.5	2.2	-2.2
Birth weight of first child	2.3	4.2	7.6	2.1	2.2	2.8	2.3	-2.0	2.2	2.2	1.4	1.8	0.8	2.1	2.2	-1.7	-1.3	-2.4	-2.1	2.3	2.4	-1.4	2.1	-1.9
Peak expiratory flow (PEF)	0.1	0.2	1.8	0.3	0.3	0.4	0.0	-1.3	0.1	0.3	-0.0	0.3	0.2	0.1	0.3	-0.2	0.0	-0.4	-0.5	0.3	0.5	-0.6	0.3	-0.0
Pulse wave reflection index	0.1	0.1	0.7	-0.1	-0.2	-0.0	-0.1	-0.1	-0.2	-0.1	-0.8	-0.8	0.6	-0.1	-0.3	-0.1	0.1	0.3	0.1	-0.2	0.0	0.1	-0.2	0.1
Ever highly irritable/argumentative for 2 days	1.9	2.3	4.8	-1.4	-1.5	-2.2	-1.7	1.8	-1.7	-1.6	-1.9	-1.2	-1.1	-1.3	-1.5	1.2	0.8	1.2	1.8	-1.6	-1.9	0.9	-1.5	1.4
Loud music exposure frequency	1.8	2.0	4.0	-1.4	-1.2	-2.0	-1.6	0.9	-1.7	-1.4	-1.8	-1.2	-0.5	-1.5	-1.5	1.0	0.8	1.4	1.7	-1.5	-2.0	0.7	-1.4	1.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.7	-0.2	-0.2	-0.1	0.3	0.1	-0.3	0.0	0.6	-0.8	0.0	-0.2	-0.3	-0.7	0.2	0.2	0.3	-0.1	-0.4	0.1	-0.1	-0.0
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.7	1.0	0.8	0.9	0.7	-1.0	1.0	0.9	0.5	-0.2	-0.2	1.1	0.9	-1.3	-1.0	-0.7	-0.7	0.8	0.7	-0.9	0.9	-1.0
Blood clot in the leg (DVT)	0.1	0.1	0.5	0.4	0.2	0.5	0.3	-0.1	0.4	0.1	-0.2	-0.1	0.2	0.6	0.2	-0.0	-0.1	-0.1	-0.4	0.1	0.7	0.6	0.1	-0.4
Medication: Paracetamol	0.3	0.5	1.7	0.9	0.6	0.6	0.9	-0.9	0.9	0.8	0.2	0.7	0.4	1.3	0.8	-1.0	-0.1	-0.7	0.1	0.7	0.6	0.1	0.7	-0.4
Headache pain in last month	0.3	0.5	1.3	-0.6	-0.6	-1.0	-0.6	-0.2	-0.8	-0.6	0.1	0.1	0.1	-0.7	-0.7	-0.0	0.8	0.7	1.1	-0.7	-0.8	1.0	-0.6	0.6
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	5.0	0.7	0.7	0.8	0.4	-0.9	0.7	0.8	-0.3	-0.4	-1.4	-0.0	0.1	0.4	-1.6	-0.4	-0.6	0.6	0.2	-2.2	0.6	-0.9
Glaucoma (self-reported)	2.2	2.5	6.5	1.6	1.5	1.8	1.3	-1.6	1.7	1.6	2.5	1.6	-0.9	1.6	1.7	-1.7	-1.1	-1.6	-1.3	1.7	1.8	-0.3	1.6	-1.8
Gout (self-reported)	0.8	1.1	2.1	1.1	1.0	1.3	1.1	-1.1	1.1	1.2	0.7	0.4	-0.4	0.7	1.3	-1.0	-0.9	-1.2	-0.7	1.2	1.1	-0.9	1.2	-1.4
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	4.5	0.5	1.0	0.4	1.2	-0.6	0.5	0.5	1.2	0.5	0.4	0.2	0.4	-0.9	-1.3	-0.7	-1.1	0.7	0.6	-2.1	0.5	-0.6
Medication: Amlodipine	0.2	0.2	2.2	0.3	0.2	0.1	-0.2	0.7	0.1	0.1	0.4	0.4	-1.5	0.6	0.2	-0.4	-0.3	-0.2	-0.3	0.2	0.2	0.1	0.2	-0.5
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.6	-0.6	-0.6	-0.7	-0.5	0.9	-0.9	-0.6	0.3	0.9	-1.2	-0.9	-0.6	0.4	0.4	0.5	0.3	-0.6	-0.3	-0.5	-0.6	0.5
Birth weight	0.2	0.5	2.1	0.7	0.6	1.3	0.5	-0.8	0.9	0.5	-0.2	0.1	0.4	0.5	0.7	0.2	-0.7	-0.7	-0.6	0.8	0.6	-1.4	0.6	-0.6
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.4	-0.2	-0.1	-0.5	0.1	0.1	-0.5	-0.1	-0.7	0.1	0.1	-0.6	-0.1	-0.1	0.5	0.1	-0.1	-0.0	0.0	-0.2	-0.1	0.6
High blood pressure (siblings)	0.7	1.0	3.5	-1.0	-0.7	-0.6	-0.7	0.9	-1.1	-0.9	-1.3	-1.1	1.9	-0.9	-0.6	1.0	1.4	0.6	0.2	-0.8	-0.3	0.7	-1.0	1.3
Forced vital capacity (FVC), Best measure	0.1	0.4	1.6	0.6	0.4	0.5	0.2	-1.3	0.6	0.6	-0.3	0.5	0.9	0.1	0.3	-0.8	-0.9	-0.7	0.2	0.6	-0.4	-1.1	0.6	-0.6
Body fat percentage	1.1	4.2	7.3	2.2	2.4	1.2	2.4	-1.5	1.8	2.1	2.1	2.1	-0.6	2.2	2.3	-2.6	-1.2	-2.3	-2.1	2.2	2.7	-0.8	2.3	-2.2
Leg fat percentage (right)	1.1	3.9	6.8	2.1	2.4	1.2	2.2	-1.6	1.8	2.0	2.4	1.8	-0.2	2.1	2.1	-2.3	-1.3	-2.1	-2.3	2.2	2.6	-0.8	2.2	-2.1
Arm fat-free mass (right)	0.0	0.1	0.6	-0.0	-0.0	-0.3	-0.7	-0.0	-0.4	-0.1	-0.4	-0.7	0.0	-0.2	-0.4	0.8	0.4	0.0	-0.2	-0.1	0.2	-0.1	-0.1	0.1
Exposure to tobacco smoke outside home	0.7	1.0	2.3	-1.2	-0.9	-1.3	-0.6	0.6	-1.2	-1.0	-1.1	-0.1	0.5	-1.3	-0.8	0.5	1.2	0.9	1.2	-0.9	-1.3	0.4	-1.0	1.5
Comparative body size at age 10	1.7	4.8	12.7	2.4	2.4	2.4	2.1	-2.2	2.4	2.3	2.0	0.1	-0.2	2.3	2.2	-1.4	-1.3	-2.3	-3.0	2.2	3.6	-1.7	2.3	-2.1
Number of full brothers	1.6	2.0	5.5	1.3	1.3	1.5	1.2	-1.8	1.0	1.3	0.7	0.4	-1.6	0.6	1.5	-1.0	-1.9	-1.4	-1.7	1.5	1.2	-2.4	1.3	-1.5
Worry too long after embarrassment	0.7	1.2	4.8	0.8	0.9	0.9	1.2	-0.6	0.7	1.1	2.2	1.6	-1.0	0.2	0.9	-1.0	-1.3	-0.9	-1.0	0.7	0.7	-1.8	0.9	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.6	-0.4	-0.3	-0.5	-0.3	0.6	-0.6	-0.5	0.0	0.1	1.6	-0.7	-0.7	0.2	-1.1	0.1	0.1	-0.3	-1.1	-0.7	-0.5	0.2
Wheeze or whistling in the chest in last year	1.0	1.8	5.1	-1.2	-1.2	-1.8	-0.9	1.2	-1.7	-1.3	-1.0	-1.4	-1.5	-1.0	-1.2	1.1	1.1	1.2	1.2	-1.2	-1.4	2.3	-1.3	1.2
Number of children fathered	2.0	2.2	4.2	1.5	1.7	1.4	2.0	-0.9	1.8	1.6	2.0	1.4	-0.7	1.6	1.6	-1.8	-0.5	-1.4	-1.1	1.6	1.8	-0.8	1.5	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	2.4	-0.9	-1.1	-0.8	-0.7	1.5	-0.9	-0.9	-0.3	-1.4	-1.3	-0.5	-1.1	0.7	1.3	1.0	1.0	-1.0	-0.8	1.5	-1.0	1.0
Age at first live birth	0.3	0.6	2.3	0.6	0.6	1.1	0.6	-0.9	0.6	0.8	0.7	1.5	0.5	0.5	0.9	-0.1	-0.7	-0.7	-1.1	0.6	0.7	-0.8	0.6	-0.2
Pulse wave peak to peak time	2.5	2.9	4.7	1.9	1.9	1.7	1.5	-1.4	1.9	1.6	1.9	1.6	-0.8	2.0	1.9	-1.1	-2.2	-1.8	-1.8	1.8	1.3	-1.8	1.8	-1.6
Health satisfaction	1.2	1.6	3.1	-1.2	-1.0	-1.5	-1.2	1.3	-1.2	-1.0	-1.5	-1.8	-0.7	-0.9	-1.4	0.7	1.2	1.2	1.7	-1.1	-1.6	1.5	-1.1	1.2
Shortness of breath walking on level ground	3.5	4.2	8.9	-2.2	-2.1	-2.6	-2.0	2.5	-2.2	-2.0	-3.0	-0.3	0.6	-2.1	-2.2	1.2	1.8	2.0	2.2	-2.1	-2.3	1.6	-2.1	2.1
Qualifications: College or University degree	1.0	3.2	5.5	1.9	1.8	2.4	1.5	-1.2	1.9	2.1	2.2	1.8	-0.1	1.6	1.9	-1.4	-1.5	-1.9	-2.0	1.9	2.3	-1.3	1.9	-2.0
Eye problems/disorders: None of the above	0.8	1.0	3.8	-1.0	-0.9	-1.9	-1.0	0.2	-1.2	-1.0	-1.4	-0.6	0.1	-1.2	-1.3	0.7	0.4	0.9	0.7	-0.9	-1.1	0.8	-0.9	0.9
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.7	-0.6	-0.9	-0.7	-0.9	1.3	-0.5	-0.8	0.5	0.8	-1.2	-0.2	-0.8	0.7	0.3	0.8	0.4	-0.8	0.1	0.8	-0.7	0.2
Emphysema/chronic bronchitis	0.6	0.7	1.2	-0.9	-0.8	-0.9	-0.7	0.9	-1.1	-1.0	-0.5	-1.1	0.9	-0.9	-0.7	0.5	0.8	0.8	0.4	-1.0	-0.5	1.0	-1.0	0.8
Medication for pain relief, constipation, heartburn	0.2	0.3	1.7	-0.3	-0.3	-0.3	-0.6	0.4	-0.5	-0.4	-0.2	0.2	-0.5	-0.6	-0.4	1.3	-0.5	0.4	-0.7	-0.5	-0.2	-0.6	-0.4	0.0
Neck or shoulder pain in last month	0.1	0.1	0.6	-0.1	-0.1	-0.7	0.0	-0.4	-0.3	-0.2	-0.6	0.5	-0.1	0.0	-0.4	-0.1	-0.1	0.1	0.8	-0.1	-0.8	0.4	-0.2	0.3
Medication: Blood pressure	0.2	0.4	2.3	0.2	0.3	0.3	0.2	0.4	0.2	0.1	0.8	1.0	1.5	0.8	0.6	-0.6	0.6	-0.3	-0.3	0.3	0.7	1.1	0.3	0.0
Angina (self-reported)	0.3	0.4	1.9	-0.7	-0.2	-0.1	-0.5	1.4	-0.5	-0.6	-0.6	-0.4	0.6	-0.3	-0.5	0.6	0.9	0.5	0.7	-0.4	-0.3	1.0	-0.6	0.7
Migraine (self-reported)	0.7	0.9	2.1	-0.9	-0.8	-1.2	-0.9	0.1	-1.1	-0.9	-1.3	-1.0	0.4	-1.4	-1.0	0.4	1.1	0.8	0.9	-0.7	-0.9	-0.3	-0.9	1.5
Medication: Ibuprofen	0.1	0.2	0.7	0.4	0.3	0.5	0.4	-0.8	0.5	0.5	0.3	0.2	0.4	0.7	0.2	-0.6	0.2	-0.2	0.5	0.4	0.1	0.2	0.3	0.1
Medication: Allopurinol	4.6	6.1	8.5	2.7	2.8	2.8	2.8	-2.8	2.7	2.7	1.9	1.3	1.0	2.5	2.8	-2.6	-2.0	-2.9	-1.9	2.8	2.9	-1.5	2.7	-2.9
Medication: Omeprazole	1.3	1.6	6.6	1.2	1.3	0.9	1.3	-2.6	1.2	1.3	0.5	0.8	-0.4	0.9	1.3	-1.9	-0.9	-1.4	-1.0	1.3	1.1	-1.4	1.3	-0.7
Medication: Seretide 50 evohaler	0.4	0.5	3.5	0.7	0.5	1.0	0.5	0.1	0.5	0.5	0.7	1.9	-0.5	0.7	0.6	-0.4	0.2	-0.7	-0.1	0.5	0.7	0.1	0.6	-0.5
Mean time to correctly identify matches	0.2	0.3	1.8	0.4	0.3	1.0	0.3	0.5	0.4	0.2	0.8	1.3	-0.2	0.4	0.3	-0.7	-0.4	-0.5	-0.0	0.3	0.5	-0.3	0.2	-0.7
Heart disease (mother)	0.5	0.6	1.3	0.8	0.8	0.6	0.6	-1.0	0.9	0.6	1.2	0.9	0.3	0.7	0.5	-0.9	-0.1	-0.7	-0.7	0.7	1.1	0.5	0.7	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	2.4	0.1	-0.2	0.1	0.0	0.1	-0.4	-0.1	-0.5	1.6	-1.6	-0.8	0.2	-0.6	-0.9	-0.0	-0.4	-0.1	-0.3	-1.4	0.0	-0.7
Whole body fat mass	0.8	3.4	7.2	2.0	2.3	1.2	2.0	-1.5	1.7	2.0	1.8	1.3	-0.5	2.1	2.0	-2.2	-0.9	-2.1	-2.1	2.1	2.7	-0.7	2.1	-1.9
Leg fat mass (right)	0.7	2.8	5.8	1.8	2.0	1.0	1.8	-1.5	1.5	1.8	1.9	1.1	-0.4	1.9	1.8	-1.9	-0.9	-1.9	-1.9	1.9	2.4	-0.5	1.9	-1.9
Arm predicted mass (right)	0.0	0.1	0.8	0.0	0.1	-0.2	-0.6	-0.1	-0.4	0.0	-0.2	-0.9	0.2	-0.2	-0.3	0.7	0.4	-0.1	-0.2	-0.0	0.2	-0.2	-0.0	0.1
Pulse rate, automated reading	0.2	0.6	2.2	-0.6	-0.8	-1.0	-0.2	-0.0	-0.8	-0.7	-1.5	-0.5	0.1	-0.9	-0.7	-0.1	0.8	0.5	1.4	-0.6	-0.9	-0.1	-0.6	0.5
Alcohol intake frequency.	3.3	7.6	10.6	-2.9	-2.9	-2.8	-3.3	3.1	-3.0	-3.0	-3.1	-2.0	-0.9	-2.7	-3.2	2.5	2.8	3.0	2.1	-3.0	-2.2	2.7	-3.0	2.7
Comparative height size at age 10	0.0	0.2	1.1	0.1	0.4	0.0	-0.7	-0.5	0.0	0.2	-0.4	-1.0	0.7	0.1	-0.2	0.4	0.2	-0.3	0.1	0.2	0.2	0.5	0.2	-0.1
Number of full sisters	0.8	1.0	2.0	-1.1	-0.9	-1.1	-0.9	1.4	-1.1	-1.1	0.3	-1.1	0.0	-0.9	-1.1	0.7	1.4	0.9	1.0	-0.8	-0.7	1.1	-0.9	1.0
Suffer from ‘nerves’	0.1	0.1	0.7	0.1	0.2	-0.1	0.5	-0.6	-0.1	0.1	-0.2	-0.7	-0.8	0.1	-0.0	-0.4	-0.4	-0.1	0.1	0.0	-0.3	-0.1	0.1	0.2
Overall health rating	2.3	5.0	9.0	-2.3	-2.4	-2.6	-2.1	2.4	-2.2	-2.3	-1.6	-2.6	0.2	-1.5	-2.3	1.7	3.0	2.3	2.5	-2.2	-1.9	2.8	-2.2	2.4
Chest pain or discomfort	1.6	2.3	4.3	-1.6	-1.4	-1.7	-1.7	1.9	-1.9	-1.6	-1.1	-1.4	-0.7	-2.1	-1.7	0.8	0.8	1.4	1.7	-1.6	-1.9	1.0	-1.5	1.0
Had major operations	0.8	0.9	2.8	1.1	0.9	0.7	1.4	-1.3	1.0	0.9	0.8	1.2	-0.9	1.1	1.0	-1.7	-0.5	-0.7	-0.3	1.0	0.7	-0.6	0.9	-0.7
Age at last live birth	0.6	0.9	2.5	0.8	0.9	1.1	0.9	-1.5	0.7	1.1	1.1	0.5	-0.3	0.9	0.9	-0.8	-0.5	-0.9	-1.6	0.8	1.3	-0.7	1.0	-0.7
Family relationship satisfaction	1.5	1.8	3.9	1.3	1.4	1.3	1.0	-0.9	1.2	1.4	1.3	1.4	0.2	1.1	1.1	-1.5	-1.8	-1.5	-1.1	1.6	1.3	-1.5	1.5	-2.0
Leg pain on walking	0.2	0.3	2.4	-0.4	-0.2	-0.4	-0.2	0.6	-0.5	-0.3	-0.5	-1.6	0.2	-0.1	-0.7	-0.4	0.8	0.3	0.5	-0.3	0.0	0.4	-0.3	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	2.5	-0.8	-0.6	-1.6	-0.4	-0.5	-1.0	-0.8	-1.4	-0.3	-1.0	-1.3	-0.7	0.0	-0.3	0.6	0.6	-0.6	-1.5	-0.7	-0.7	1.0
Commuting to job workplace: Car/motor vehicle	0.9	1.1	2.8	1.0	1.0	0.8	1.2	-1.7	1.0	1.0	-0.0	1.5	-1.0	1.0	1.2	-1.5	-0.9	-0.9	-0.4	0.9	0.6	-0.5	1.1	-1.0
Illness, injury, bereavement, stress in last 2 years	2.9	3.6	6.0	1.9	2.1	1.6	1.6	-1.7	2.0	1.8	2.0	2.1	1.0	2.1	2.0	-1.1	-2.4	-1.9	-2.4	1.9	2.0	-1.6	1.9	-1.9
Medication: Aspirin	0.1	0.2	0.9	-0.0	0.1	0.1	0.3	0.1	0.2	-0.0	0.2	0.4	-0.2	0.3	0.1	-1.0	0.5	-0.2	0.8	0.2	0.0	0.9	0.1	-0.1
Supplements: Vitamin C	0.6	0.7	2.6	0.8	0.9	1.1	0.6	-0.2	0.9	0.9	0.6	-1.0	1.6	0.8	0.9	-0.4	-0.7	-1.1	-0.4	0.9	0.6	-0.2	1.0	-0.7
Knee pain experienced in last month	0.4	0.6	1.2	0.8	0.9	0.7	0.9	-1.1	0.5	0.7	0.5	0.5	0.0	0.9	1.0	-0.5	-0.7	-0.9	-1.1	0.7	0.8	-0.7	0.8	-0.6
Hypertension (Self-reported)	0.2	0.5	2.1	0.8	0.7	0.3	0.4	-0.4	0.8	0.6	0.7	0.7	-0.2	1.4	0.8	-1.1	0.4	-0.6	-0.4	0.7	1.0	0.6	0.8	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.3	-0.2	-0.0	0.4	-0.2	-0.1	-0.4	-0.3	-0.5	-0.2	0.5	-0.5	-0.1	0.2	0.2	-0.1	-0.3	-0.1	-0.0	-0.2	-0.2	0.5
Illnesses of father: Heart disease	0.2	0.3	1.8	-0.1	-0.0	0.1	0.0	0.9	-0.4	-0.4	-0.3	0.7	-0.0	-0.3	-0.1	-0.5	1.2	0.2	0.8	-0.2	0.2	1.3	-0.2	-0.2
Illnesses of siblings: Diabetes	0.3	0.3	2.7	0.4	0.3	0.3	0.3	0.0	0.3	0.4	1.0	0.6	-1.7	0.5	0.3	-0.8	0.7	-0.5	0.2	0.4	0.6	-0.3	0.3	-0.3
Smoking status: Previous	0.6	1.0	3.0	0.8	1.0	0.7	1.5	-1.2	0.7	0.7	1.7	0.0	0.1	0.9	0.8	-1.6	-1.1	-1.0	-0.9	0.9	0.5	-0.8	0.8	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	0.8	-0.5	-0.6	-0.5	-0.9	-0.3	-0.4	-0.4	-0.9	-0.8	0.2	-0.8	-0.6	0.5	0.8	0.6	0.7	-0.6	-0.5	0.2	-0.5	0.8
Whole body fat-free mass	0.0	0.1	0.5	0.2	0.4	0.1	-0.2	-0.4	-0.1	0.3	-0.4	-0.7	0.0	0.0	0.0	0.5	0.2	-0.3	-0.5	0.3	0.6	-0.4	0.3	-0.2
Leg fat-free mass (right)	0.1	0.3	1.1	0.6	0.8	0.3	0.3	-0.6	0.2	0.7	-0.2	-0.1	-0.5	0.3	0.5	-0.3	0.0	-0.8	-0.8	0.7	1.1	-0.5	0.7	-0.6
Arm fat percentage (left)	1.3	5.3	9.1	2.4	2.7	1.8	2.8	-1.8	2.1	2.4	2.0	2.0	-0.7	2.3	2.7	-2.8	-1.5	-2.5	-2.5	2.5	3.0	-1.5	2.5	-2.4
Average weekly red wine intake	0.2	0.3	1.5	0.2	0.3	0.5	0.4	-0.4	0.4	0.4	-0.2	1.0	1.2	-0.0	0.4	0.1	-0.9	-0.3	-0.4	0.4	0.1	-0.8	0.4	-0.7
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.4	-0.1	-0.2	-0.5	-0.6	0.6	-0.1	-0.1	0.6	0.5	0.2	-0.1	-0.4	0.6	0.0	0.1	0.4	-0.3	-0.2	0.5	-0.1	-0.0
Mood swings	0.4	0.7	1.7	-0.8	-0.8	-1.0	-1.0	0.1	-0.8	-1.0	-0.9	-0.9	0.2	-0.9	-1.2	0.8	-0.1	0.9	0.5	-1.0	-1.3	-0.7	-1.0	0.9
Loneliness, isolation	0.4	0.6	2.2	-0.6	-0.5	-0.6	-0.5	0.6	-0.6	-0.5	-1.3	-1.2	1.5	-1.2	-0.6	0.4	-0.1	0.5	0.6	-0.5	-0.9	-0.6	-0.5	0.4
Long-standing illness, disability or infirmity	2.2	3.3	6.9	-1.8	-1.9	-2.0	-1.8	2.1	-1.8	-1.9	-1.0	-2.6	0.7	-1.4	-1.9	1.2	1.7	1.8	2.1	-1.9	-2.1	1.9	-1.9	1.7
Ever had bowel cancer screening	1.2	1.4	3.8	-1.3	-1.2	-1.1	-1.4	1.0	-0.9	-1.3	-1.2	-0.9	0.1	-0.7	-1.4	1.9	1.4	1.1	1.3	-1.2	-0.6	1.5	-1.2	0.9
Diabetes diagnosed by doctor	0.2	0.3	0.8	0.4	0.3	0.0	0.7	0.7	0.4	0.3	0.9	0.1	-0.3	0.7	0.6	-0.9	-0.2	-0.6	-0.3	0.3	0.6	-0.4	0.4	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	7.1	7.6	14.3	-2.8	-2.8	-2.6	-3.0	3.1	-3.0	-2.8	-2.4	-1.4	-0.4	-2.5	-3.0	2.4	3.3	2.9	2.8	-2.9	-2.6	3.8	-2.8	2.9
Friendships satisfaction	0.2	0.2	1.3	-0.2	0.0	-0.2	-0.1	0.2	-0.5	0.1	0.4	1.0	0.8	-0.6	-0.2	-0.2	-1.1	-0.1	-0.5	0.1	-0.3	-0.0	0.0	-0.9
Qualifications: nursing, teaching	0.2	0.3	2.2	0.2	0.1	0.9	0.0	0.4	0.0	0.2	0.6	1.5	1.2	-0.3	-0.1	-0.6	0.6	-0.0	0.2	0.1	0.2	-0.2	0.0	-0.1
Commuting to job workplace: Walk	0.1	0.2	0.5	0.5	0.6	0.6	0.3	-0.7	0.1	0.5	0.1	-0.6	-0.3	0.0	0.4	0.0	-0.0	-0.5	-0.2	0.5	0.3	-0.3	0.4	-0.3
Eye problems/disorders: Cataract	0.3	0.4	1.4	-0.3	-0.4	0.6	-0.5	1.2	-0.2	-0.4	0.0	-0.8	0.4	0.5	-0.1	1.2	0.8	0.4	0.5	-0.3	-0.3	0.8	-0.4	0.7
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.5	-0.3	-0.3	-1.0	-0.4	-0.4	-0.3	-0.4	-0.4	-1.2	-0.6	0.1	-0.4	0.5	-0.1	0.3	-0.0	-0.3	-0.7	0.4	-0.4	0.5
Medication for cholesterol	0.3	0.5	1.4	-0.6	-0.8	-0.6	-0.8	0.3	-0.9	-0.8	-0.8	-0.0	1.1	-1.2	-0.8	0.1	0.4	0.6	0.8	-0.7	-0.9	0.6	-0.8	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.7	3.1	7.0	-1.8	-1.8	-1.5	-2.0	1.9	-1.7	-1.9	-1.8	-0.2	1.3	-1.6	-1.6	1.8	2.5	1.8	1.9	-1.7	-1.0	2.6	-1.8	1.6
Back pain experienced in last month	0.1	0.2	0.7	0.2	0.3	0.3	0.5	-0.9	0.1	0.4	0.6	0.3	0.8	0.3	0.3	-0.2	0.0	-0.4	-0.5	0.5	0.4	0.3	0.3	0.1
Mineral and other dietary supplements	5.3	7.2	10.7	-2.8	-3.0	-3.3	-2.8	3.3	-2.9	-2.7	-2.2	-1.9	-0.5	-2.2	-2.9	2.4	2.6	3.0	2.7	-2.9	-3.0	2.3	-2.8	2.8
Breast cancer (self-reported)	2.7	3.3	5.8	1.9	1.9	1.9	2.0	-1.2	1.9	1.8	1.2	2.4	-0.1	1.1	2.1	-1.9	-1.7	-1.8	-1.4	1.8	1.9	-2.2	1.9	-2.1
Asthma (self-reported)	0.1	0.1	0.5	-0.0	-0.1	0.3	-0.2	0.4	-0.3	-0.0	0.4	0.3	-0.6	-0.4	0.0	0.5	0.3	0.1	0.2	-0.1	-0.0	-0.7	-0.2	0.3
Osteoporosis (self-reported)	0.3	0.4	3.1	-0.1	0.1	0.7	-0.4	0.5	0.0	-0.1	1.3	-1.0	1.8	-0.1	-0.1	0.4	0.1	-0.1	-1.1	-0.1	0.6	-0.5	-0.1	0.4
Osteoarthritis (self-reported)	0.7	0.9	2.8	-0.9	-0.7	-0.9	-1.1	0.1	-0.7	-0.9	-1.7	-1.7	0.3	-1.1	-1.1	0.8	0.5	0.8	1.0	-0.8	-1.2	0.3	-0.8	0.7
Medication: Aspirin	0.1	0.1	0.8	0.0	0.0	0.2	0.2	0.2	0.2	-0.0	0.2	0.1	-0.3	0.4	0.1	-0.9	0.4	-0.2	0.7	0.2	0.0	0.7	0.1	-0.1
Medication: Gliclazide	0.5	0.6	1.4	0.9	0.8	0.8	0.7	0.1	0.8	0.8	0.8	0.2	1.2	1.2	0.8	-0.4	-0.9	-1.0	-0.1	0.8	0.4	-0.3	0.9	-0.9
Illnesses of father: None of the above (group 1)	0.6	0.8	3.7	0.6	0.3	0.1	0.4	-1.6	0.7	0.7	0.8	0.1	-1.8	0.3	0.4	-0.6	-1.6	-0.5	-0.6	0.6	-0.3	-1.9	0.6	-0.5
Smoking status: Current	3.5	5.5	9.0	-2.8	-2.6	-2.7	-2.4	2.2	-2.5	-2.4	-3.0	-0.3	-0.6	-2.5	-2.7	2.6	2.0	2.5	2.1	-2.5	-2.4	2.1	-2.5	2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.4	15.6	20.9	4.6	4.0	4.6	4.2	-3.9	4.5	4.4	2.8	3.1	-0.5	4.2	4.2	-4.5	-3.8	-4.1	-2.7	4.3	3.7	-4.0	4.3	-4.4
Whole body water mass	0.0	0.1	0.8	-0.0	0.1	-0.2	-0.5	-0.2	-0.4	0.0	-0.6	-0.9	0.1	-0.3	-0.3	0.7	0.4	-0.1	-0.3	-0.0	0.3	-0.2	-0.0	0.1
Leg predicted mass (right)	0.1	0.3	1.1	0.7	0.8	0.4	0.4	-0.6	0.3	0.7	-0.2	-0.0	-0.5	0.3	0.5	-0.2	-0.1	-0.8	-0.8	0.7	1.1	-0.5	0.7	-0.7
Arm fat mass (left)	0.7	3.0	6.6	1.9	2.1	1.2	2.0	-1.4	1.5	1.9	1.4	1.1	-0.8	1.8	2.0	-1.9	-0.8	-2.0	-2.1	2.0	2.6	-0.9	2.0	-1.8
Number of self-reported non-cancer illnesses	0.1	0.2	1.7	-0.3	-0.1	-0.5	-0.2	0.4	-0.5	-0.4	0.4	-0.6	-0.1	0.3	-0.3	-0.6	0.8	0.2	0.5	-0.2	-0.3	1.3	-0.3	0.3
Average weekly champagne plus white wine intake	1.6	2.3	5.0	1.5	1.6	1.4	1.4	-2.2	1.6	1.4	1.5	2.1	0.1	1.1	1.4	-1.6	-1.2	-1.4	-1.3	1.4	1.8	-0.9	1.4	-1.8
Miserableness	0.2	0.4	0.9	-0.6	-0.5	-0.6	-0.4	0.2	-0.6	-0.7	-0.6	-0.9	0.1	-0.1	-0.8	0.5	0.4	0.8	0.5	-0.7	-0.6	0.5	-0.7	0.9
Guilty feelings	0.2	0.3	1.3	-0.5	-0.3	-0.7	-0.6	0.4	-0.6	-0.5	0.1	-0.6	1.1	-0.7	-0.7	0.3	-0.5	0.4	0.1	-0.5	-0.8	-0.4	-0.5	0.3
Wears glasses or contact lenses	0.5	0.6	1.9	-0.6	-0.7	-0.2	-0.4	0.7	-0.7	-0.6	0.2	-0.3	-1.4	-1.1	-0.6	0.6	-0.3	0.8	0.8	-0.7	-1.2	-1.3	-0.7	0.5
Ever taken oral contraceptive pill	0.3	0.3	4.7	-0.4	-0.1	-0.2	-0.4	-0.1	-0.5	-0.3	0.2	-0.3	2.2	-0.4	-0.5	0.8	0.1	0.3	0.0	-0.2	-0.6	0.1	-0.3	0.3
Hearing aid user	1.8	2.0	3.0	-1.4	-1.3	-1.6	-1.7	1.7	-1.4	-1.6	-1.5	-1.3	0.6	-1.4	-1.7	1.4	1.3	1.1	1.5	-1.4	-1.3	1.5	-1.5	1.1
Mother’s age at death	2.6	3.2	4.8	2.0	1.9	2.0	1.7	-1.5	2.0	2.0	1.4	1.0	0.8	1.8	2.0	-1.7	-1.5	-2.1	-1.4	1.9	2.2	-1.7	2.1	-2.1
Financial situation satisfaction	0.5	0.6	3.2	-0.8	-0.7	-1.1	-0.5	1.8	-0.9	-0.7	0.6	-0.3	0.4	-0.5	-0.6	-0.1	0.9	0.7	0.3	-0.6	-0.4	1.2	-0.7	0.7
Tinnitus: Yes, now most or all of the time	2.0	2.3	4.0	1.8	1.7	1.4	1.7	-1.2	2.0	1.7	0.8	1.4	1.0	1.9	1.6	-1.7	-1.0	-1.7	-0.7	1.7	1.7	0.1	1.7	-2.0
Commuting to job workplace: Public transport	0.8	0.9	3.7	-0.9	-1.1	-0.8	-1.0	0.8	-1.0	-1.0	-0.7	-1.9	0.5	-1.3	-1.0	0.6	0.8	1.0	0.6	-1.0	-0.8	-0.5	-1.0	1.1
Eye problems/disorders: Glaucoma	3.0	3.5	7.2	1.9	1.8	2.2	1.5	-1.8	2.1	2.0	2.6	1.5	-1.3	2.2	2.0	-1.8	-0.8	-1.9	-1.7	2.0	2.7	-0.0	2.0	-1.8
Medication: Blood pressure	0.1	0.3	1.2	0.4	0.6	0.1	0.1	-0.0	0.5	0.5	1.1	-0.2	-0.8	0.9	0.5	-0.0	-0.1	-0.4	-0.3	0.5	0.6	-0.0	0.6	-0.1
Pain type(s) experienced in last month: Hip pain	2.5	3.1	5.6	1.8	1.9	1.7	1.7	-2.3	1.3	1.8	1.9	1.2	-1.1	1.7	1.7	-1.8	-1.6	-1.9	-2.4	1.8	2.2	-1.5	1.8	-1.5
Supplements: Fish oil (including cod liver oil)	6.6	8.6	11.6	3.1	3.2	3.3	3.3	-2.7	3.0	3.1	2.9	2.3	0.4	2.7	3.4	-3.2	-2.9	-3.2	-2.9	3.2	3.0	-2.5	3.1	-3.0
High cholesterol (Self-reported)	0.1	0.2	1.6	-0.1	-0.1	-0.5	0.2	-0.1	0.1	-0.0	0.1	-0.0	-1.3	0.3	0.2	-0.3	0.9	0.0	-0.1	-0.1	0.6	0.7	0.0	0.5
Medication: Bendroflumethiazide	0.7	1.0	2.1	0.9	1.2	1.1	1.1	-0.7	1.3	1.2	1.2	0.3	0.4	1.4	1.2	-0.8	0.2	-1.0	-0.7	1.2	1.3	0.8	1.1	-0.7
Medication: Paracetamol	0.1	0.2	0.9	-0.0	-0.3	-0.2	0.0	-0.2	-0.1	-0.1	-0.7	-0.7	0.1	0.4	-0.1	0.2	0.6	0.3	0.9	-0.2	-0.3	0.5	-0.2	0.5
Medication: Lisinopril	0.5	0.7	1.9	-0.6	-0.7	-0.9	-0.9	1.0	-0.7	-0.6	-0.5	-0.9	0.6	-0.2	-0.4	0.6	1.3	0.6	1.3	-0.6	-0.8	1.4	-0.6	0.8
Medication: Atorvastatin	0.2	0.3	1.4	-0.2	-0.0	0.1	0.1	0.5	0.2	-0.1	-0.1	0.6	1.2	0.0	0.1	0.2	0.9	-0.1	1.0	-0.0	-0.0	1.1	-0.1	0.1
Illnesses of father: High blood pressure	0.1	0.2	1.4	0.2	0.1	0.0	-0.0	0.1	-0.4	0.2	0.3	1.2	0.2	-0.1	0.1	-0.8	0.6	-0.2	0.4	0.1	0.2	0.3	0.0	0.2
Alcohol drinker status: Never	3.5	4.2	8.2	-2.1	-2.3	-1.7	-2.6	2.9	-1.9	-2.2	-0.6	-1.2	-0.2	-1.6	-2.1	2.0	2.7	2.1	2.2	-2.2	-1.5	2.8	-2.2	2.0
Ever smoked	0.1	0.1	0.6	-0.1	0.1	0.1	0.7	-0.7	0.0	-0.0	0.1	0.6	-0.5	-0.0	0.1	-0.2	-0.4	-0.1	-0.2	0.1	-0.1	-0.1	0.1	-0.3
Basal metabolic rate	0.0	0.2	0.8	0.5	0.7	0.2	0.1	-0.6	0.2	0.6	-0.2	-0.4	-0.1	0.3	0.3	0.1	-0.0	-0.6	-0.7	0.6	0.9	-0.5	0.6	-0.5
Leg fat percentage (left)	1.2	4.4	7.7	2.2	2.5	1.2	2.3	-1.7	1.9	2.2	2.5	2.0	-0.3	2.3	2.2	-2.5	-1.4	-2.3	-2.3	2.3	2.8	-0.9	2.3	-2.2
Arm fat-free mass (left)	0.0	0.2	0.7	-0.1	-0.0	-0.5	-0.7	-0.1	-0.5	-0.1	-0.6	-0.7	0.1	-0.4	-0.5	0.9	0.5	0.1	-0.2	-0.2	0.2	0.1	-0.1	0.2
Number of operations (self-reported)	4.5	6.8	9.1	2.7	2.8	3.0	3.0	-3.0	2.6	2.8	1.7	2.8	-1.4	2.6	2.6	-2.7	-2.8	-2.6	-2.2	2.7	2.1	-2.3	2.6	-2.8
Average weekly beer plus cider intake	5.8	8.3	13.5	-2.9	-3.1	-3.5	-2.7	2.5	-2.8	-3.1	-3.5	-3.7	0.2	-2.5	-3.1	2.7	2.4	2.9	2.9	-3.0	-3.4	2.1	-3.0	2.9
Irritability	0.9	1.5	4.6	-1.1	-1.1	-1.6	-1.2	0.7	-1.4	-1.2	-1.0	-2.1	-0.9	-1.4	-1.4	1.2	-0.6	0.9	0.8	-1.1	-2.1	-0.6	-1.2	0.8
Risk taking	0.3	0.5	2.4	-0.5	-0.5	-0.6	-0.5	-0.1	-0.4	-0.5	-1.5	-1.0	-1.0	-0.5	-0.8	0.3	-0.2	0.5	0.8	-0.5	-1.1	-0.0	-0.5	0.1
Ever had prostate specific antigen (PSA) test	2.0	2.3	6.1	1.4	1.7	1.3	1.4	-0.5	1.8	1.4	2.1	0.6	2.5	1.8	1.3	-1.0	-1.5	-1.6	-1.8	1.4	1.8	-0.8	1.4	-1.5
Fractured/broken bones in last 5 years	0.7	0.9	2.3	-0.8	-0.9	-0.6	-1.0	1.5	-0.9	-0.9	-0.3	-1.4	-1.0	-0.6	-0.8	1.4	0.4	1.1	0.5	-1.1	-1.2	-0.1	-1.0	1.3
Age started oral contraceptive pill	1.0	1.3	1.9	1.0	1.2	1.0	1.2	-0.8	1.2	1.1	1.2	1.3	-1.3	0.9	0.9	-1.2	-1.3	-1.1	-1.4	1.2	1.0	-0.9	1.2	-1.3
Diastolic blood pressure, automated reading	0.0	0.2	0.8	0.2	-0.3	-0.4	-0.0	-0.2	-0.2	-0.1	-0.9	-0.6	0.2	-0.4	-0.2	-0.8	0.2	-0.0	0.6	-0.1	-0.3	-0.6	-0.1	-0.3
Ever depressed for a whole week	0.4	0.4	0.7	-0.7	-0.6	-0.7	-0.7	0.7	-0.8	-0.7	-0.5	0.2	-0.4	-0.8	-0.8	0.4	0.8	0.7	0.6	-0.8	-0.5	0.5	-0.8	0.7
Unable to work because of sickness or disability	0.0	0.0	0.2	-0.1	-0.1	0.1	-0.2	0.1	-0.1	-0.3	-0.2	-0.0	0.4	-0.3	-0.1	-0.2	-0.1	0.1	-0.2	-0.1	-0.1	0.1	-0.2	-0.1
Commuting to job workplace: Cycle	0.5	0.6	1.5	0.7	0.8	0.8	0.6	0.1	0.9	0.8	0.7	1.2	-0.7	0.6	0.7	-0.6	-0.8	-0.8	-0.5	0.7	0.7	-0.2	0.7	-1.2
Myopia	1.0	1.5	2.4	1.2	1.3	1.0	1.5	-1.4	1.3	1.5	1.5	0.9	-0.8	1.1	1.5	-1.3	-0.9	-1.2	-0.8	1.4	1.0	-1.0	1.5	-0.8
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.0	-0.8	-0.7	-0.5	-0.6	0.4	-0.8	-0.7	-0.9	-0.8	0.6	-1.4	-0.9	1.3	-0.3	0.7	0.3	-0.7	-0.9	-0.4	-0.8	0.4
Cholesterol lowering medication	0.2	0.3	1.3	0.3	0.4	0.7	0.5	0.3	0.7	0.6	0.3	-0.8	-1.1	0.8	0.4	-0.5	0.6	-0.2	0.1	0.3	0.9	0.6	0.4	-0.3
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	4.5	1.5	1.6	1.3	1.8	-2.0	1.3	1.6	0.9	1.0	-0.2	1.0	1.7	-2.1	-1.1	-1.9	-1.3	1.7	1.5	-1.8	1.6	-1.1
Pain experienced in last month	1.3	2.2	4.0	1.7	1.5	1.6	1.5	-0.5	1.9	1.4	1.3	0.3	-0.8	1.3	1.5	-1.4	-1.4	-1.6	-1.5	1.5	1.8	-2.0	1.6	-1.8
Supplements: Calcium	0.3	0.4	3.4	0.2	0.3	1.0	0.4	-0.8	0.6	0.1	0.1	0.4	1.8	0.4	0.2	-0.2	0.2	-0.3	-0.5	0.3	0.9	-0.0	0.2	-0.3
Basal cell carcinoma (self-reported)	1.0	1.2	2.7	-1.0	-0.9	-1.4	-1.2	1.2	-0.9	-0.9	-0.6	-0.4	0.3	-0.1	-1.3	1.1	1.6	1.0	1.5	-1.0	-1.0	1.6	-1.0	1.5
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.0	-0.2	-0.2	-0.6	0.4	0.9	-0.2	-0.3	-0.3	-0.1	-0.4	0.1	-0.2	-0.7	1.4	0.4	1.4	-0.3	0.2	1.3	-0.2	0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.9	0.6	0.3	0.7	0.5	-0.4	0.6	0.2	-0.2	0.3	0.1	0.8	0.4	-0.1	-0.2	-0.3	-0.6	0.3	1.0	0.5	0.3	-0.4
Heart disease (siblings)	1.6	2.0	3.7	-1.6	-1.6	-1.0	-1.4	1.4	-1.5	-1.7	-1.1	-1.7	0.1	-1.5	-1.3	1.4	1.9	1.4	1.1	-1.3	-1.2	1.3	-1.6	1.9
Alcohol drinker status: Previous	1.4	1.6	3.3	-1.3	-1.5	-1.5	-1.2	0.8	-1.5	-1.4	-1.8	-1.3	-0.6	-1.6	-1.7	0.6	0.3	1.4	0.8	-1.4	-1.6	-0.1	-1.4	1.0
Pack years of smoking	1.1	1.6	3.0	-1.5	-1.5	-1.2	-1.0	1.1	-1.3	-1.2	-0.9	0.7	0.2	-1.3	-1.5	0.9	1.4	1.4	1.7	-1.3	-1.5	1.6	-1.4	1.4
Impedance of whole body	0.1	0.3	2.1	0.3	0.1	0.0	0.5	-0.2	0.5	0.1	0.3	1.4	0.6	0.4	0.3	-1.1	-0.9	-0.3	0.3	0.3	-0.4	0.1	0.2	-0.6
Leg fat mass (left)	0.7	2.7	5.6	1.8	2.0	0.9	1.8	-1.4	1.4	1.7	1.8	1.1	-0.5	1.9	1.8	-1.9	-0.9	-1.8	-1.8	1.8	2.4	-0.6	1.8	-1.8
Arm predicted mass (left)	0.0	0.1	0.7	-0.0	0.1	-0.4	-0.6	-0.2	-0.4	0.0	-0.4	-0.6	0.2	-0.2	-0.4	0.8	0.4	-0.0	-0.3	-0.1	0.4	0.0	-0.0	0.1