Hub : Genes

TMCC2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1700	0.0350	1.2e-13	0.183	0.140	0.178	0.171	0.187	9.2e-22	1.2e-16	3.9e-21	2.4e-20	3.0e-22
2	GTEx	Artery Aorta	0.3650	0.0690	1.3e-07	0.149	NA	0.115	NA	0.172	1.4e-08	NA	6.7e-07	NA	9.3e-10
3	GTEx	Artery Tibial	0.3602	0.0623	1.5e-12	0.139	NA	0.255	NA	0.259	5.0e-11	NA	5.4e-20	NA	2.3e-20
4	GTEx	Heart Left Ventricle	0.1530	0.0567	3.9e-03	0.144	NA	0.120	NA	0.121	4.3e-08	NA	6.1e-07	NA	5.5e-07
5	GTEx	Muscle Skeletal	0.0413	0.0192	8.4e-03	0.043	NA	0.029	NA	0.031	4.0e-05	NA	6.3e-04	NA	4.4e-04
6	NTR	Blood	0.0148	0.0070	7.2e-03	0.000	0.004	0.002	0.003	0.002	2.2e-01	1.3e-02	8.8e-02	2.4e-02	4.9e-02
7	YFS	Blood	0.0321	0.0101	2.6e-06	0.018	0.017	0.016	0.016	0.014	7.9e-07	2.5e-06	5.2e-06	3.7e-06	1.7e-05
8	TCGA	Breast Invasive Carcinoma	0.0691	0.0304	3.0e-04	0.002	0.013	0.008	NA	0.006	1.1e-01	8.1e-04	6.6e-03	NA	1.6e-02
9	TCGA	Lung Squamous Cell Carcinoma	0.0303	0.0172	9.8e-03	0.031	0.016	0.017	NA	0.026	1.6e-04	5.6e-03	4.1e-03	NA	5.4e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.7	2.7	7.7	-2.8	0.2	-0.6	-0.2	2.0	-2.5	-1.6	1.8	0.6
Bipolar Disorder or Schizophrenia	0.1	0.3	0.6	0.1	-0.6	0.1	0.7	-0.7	0.8	0.4	-0.2	-0.7
Depressed Affect (Nagel 2018)	1.9	4.1	8.4	-2.1	2.7	2.6	-2.9	-0.2	-0.0	-1.3	-1.2	2.6
Depression (Nagel 2018)	1.7	2.6	5.2	-2.1	2.3	1.5	-2.0	0.3	-0.4	-1.7	-0.2	2.1
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.4	-1.4	-0.3	-0.1	-0.2	0.3	-1.6	-0.0	0.7	0.7
Neuroticism (Nagel 2018)	1.5	3.5	7.4	-2.7	2.6	2.2	-2.4	-0.0	-0.3	-1.0	-0.9	2.2
Schizophrenia (2018)	1.7	3.5	8.9	2.4	-0.9	0.6	1.2	-2.5	3.0	1.8	-1.7	-1.4
Schizophrenia vs Biploar Disorder	2.2	2.9	5.9	1.1	1.5	2.3	-1.2	-2.3	2.4	0.3	-2.1	0.9
Worry (Nagel 2018)	1.5	3.2	7.8	-2.7	2.8	1.9	-2.1	0.1	-0.5	-1.0	-0.1	2.0
Alzheimer’s Disease (in mother)	0.9	1.0	2.2	0.6	-1.5	-0.6	0.7	-0.2	1.3	1.0	-1.5	-0.8
Alzheimer’s Disease (in father)	1.6	1.8	3.8	2.0	-1.7	-0.5	1.6	-1.1	0.8	1.1	-0.4	-1.8
Alzheimer’s Disease (including proxy)	1.6	2.3	4.9	1.3	-2.2	-1.1	1.6	-0.4	1.4	1.8	-1.5	-1.8
Crohns Disease (2017)	0.2	0.5	1.3	0.4	-1.1	-0.5	0.9	0.3	0.1	-0.6	-0.2	-1.1
Irritable Bowel Disease (IBD)	0.3	0.7	4.1	-0.2	-0.2	0.4	0.1	0.6	-0.9	-2.0	-0.5	-0.5
Ulcerative Colitis (UC)	0.8	1.5	7.5	-0.8	0.5	1.0	-0.7	0.6	-1.8	-2.7	-0.3	0.4
Major Depression (MDD)	0.3	0.4	2.0	-0.2	0.7	0.1	-0.1	0.4	-1.4	-0.8	0.2	-0.3
Reaction Time	1.1	2.0	3.9	-1.9	1.6	1.2	-1.6	0.1	-0.1	-0.8	-2.0	1.8
Verbal and Numeric Reasoning (VNR)	0.3	0.6	2.7	-0.6	-0.1	-0.0	-0.0	0.1	-1.5	0.6	1.6	0.4
Breast Cancer	0.4	0.9	2.8	0.3	1.0	0.9	-0.9	-0.5	-1.7	0.5	-1.4	0.7
Ovarian Cancer	1.5	1.9	4.8	0.9	-0.1	0.8	-0.2	-1.8	2.2	2.1	-1.8	0.2
Prostate Cancer	0.9	1.3	3.4	-0.1	-1.2	-1.7	1.4	1.8	-0.8	-0.3	0.4	-1.1
Age at First Birth	0.5	0.7	2.1	1.3	0.4	0.9	-0.2	-1.4	0.8	0.2	-1.0	0.0
Bipolar Disorder (2011)	2.4	2.3	5.7	-2.2	0.7	-0.5	-0.1	1.8	-2.4	-1.6	1.9	0.6
Body Mass Index (BMI) (2010)	1.4	2.0	3.9	0.7	1.2	1.9	-1.0	-1.8	1.8	-0.7	-2.0	0.5
Coronary Artery Disease (CAD)	0.2	0.2	0.4	0.1	-0.4	-0.6	0.6	0.6	0.0	-0.1	-0.3	-0.6
Crohns Disease (2012)	0.1	0.1	0.4	-0.2	-0.5	-0.6	0.5	0.2	-0.1	-0.4	0.3	-0.3
Mean Putamen Volume	2.7	3.1	7.7	-1.4	2.6	1.7	-2.6	-1.0	-0.4	-0.4	-0.6	2.8
Fasting Glucose	0.6	0.7	1.6	0.8	1.1	1.1	-0.8	-1.2	0.4	-0.5	-0.5	0.8
HbA1C	0.4	0.4	2.0	0.0	-0.6	-0.8	0.5	0.4	1.4	-0.1	-0.6	-0.4
HDL Cholesterol	0.5	0.9	2.2	-1.5	0.4	-0.8	0.4	1.5	-1.2	-0.2	0.9	0.1
LDL Cholesterol	0.1	0.2	0.9	0.4	-0.3	-0.3	0.4	-0.2	0.1	1.0	-0.6	-0.5
Lupus	1.5	2.3	7.6	2.8	-0.8	0.2	0.5	-1.2	2.3	1.9	1.2	-0.9
Neuroticism (2016)	1.3	1.9	5.3	-0.1	2.3	1.9	-2.0	-0.6	-0.0	-0.7	0.8	1.6
Primary Biliary Cirrhosis	0.3	0.4	1.0	-0.9	0.9	0.1	-0.7	-0.1	0.9	0.4	-0.2	1.0
Rheumatoid Arthritis	0.7	0.9	3.1	1.1	-1.8	-0.9	1.0	0.0	0.8	0.6	-0.4	-0.9
Schizophrenia (2014)	0.9	1.9	6.2	1.4	0.1	1.2	0.4	-2.5	2.1	1.3	-0.9	-0.6
Triglycerides	0.4	0.7	2.2	1.1	-0.8	-0.4	0.9	0.2	-0.3	-0.2	1.5	-1.2
Type 2 Diabetes (T2D) (2012)	0.2	0.3	0.7	0.4	-0.8	-0.1	0.7	0.1	0.6	0.3	-0.1	-0.9
Ulcerative Colitis	1.5	2.2	9.5	-1.2	0.4	0.1	-0.2	1.4	-2.5	-3.1	0.7	0.0
Blood Eosinophil Count	0.0	0.4	1.0	0.2	0.5	0.8	-0.4	-0.8	1.0	-0.5	0.1	0.2
Blood Platelet Count	25.1	291.1	670.8	-25.9	7.3	-2.1	-6.8	20.2	-25.2	-24.5	11.0	9.0
Blood Red Count	6.7	64.8	146.4	12.1	-4.3	1.5	4.2	-9.5	11.8	10.3	-5.6	-5.7
Blood White Count	1.1	8.3	22.4	1.9	-4.0	-2.7	4.2	1.9	0.5	-1.7	-1.4	-4.7
Heel T-Score	0.3	2.7	5.8	0.4	2.0	2.4	-2.2	-1.7	0.4	1.2	-1.1	1.9
BMI	0.5	2.9	7.5	1.3	1.7	2.3	-1.5	-2.2	2.7	0.9	-0.3	1.0
Height	0.3	6.7	17.1	-3.6	2.4	-0.3	-2.0	1.9	-2.5	-4.1	0.9	3.0
Waist Hip Ratio (WHR)	1.4	6.1	19.0	2.5	-3.3	-1.5	3.5	1.1	-0.0	-0.7	-1.7	-4.4
Systolic Blood Pressure	0.8	3.8	11.7	3.4	-0.9	0.4	1.3	-2.3	1.5	2.7	-1.3	-1.9
Smoking Status	1.2	3.0	10.4	2.1	-0.5	0.7	0.4	-1.6	2.3	1.5	-3.2	-0.9
Allergy or Eczema	1.7	4.5	10.3	2.7	-2.7	-1.9	2.9	-0.3	1.0	1.6	-0.4	-3.2
Cardiovascular Disease	0.4	1.3	6.0	2.5	-0.5	0.7	0.7	-1.2	0.5	0.7	-0.3	-1.5
Hypothyroidism (self reported)	0.8	1.7	3.0	0.3	1.5	1.7	-1.5	-1.6	1.1	1.4	0.5	1.4
Respiratory disease	1.1	2.4	5.7	1.4	-2.4	-1.0	2.0	-0.3	0.6	1.4	-1.2	-2.3
Type 2 Diabetes (T2D) (2018)	2.3	4.3	11.5	3.4	-2.3	-0.4	1.9	-1.2	2.5	1.6	-0.2	-2.8
Lung FEV1/FVC ratio	2.8	14.0	38.3	-2.2	-2.4	-2.9	2.4	5.5	-4.5	-6.2	1.9	-2.8
Lung FVC	1.1	5.6	17.2	-2.7	2.9	1.6	-3.3	-0.7	-1.0	1.5	0.4	4.1
Neuroticism	1.3	3.2	6.6	-2.6	2.6	1.9	-2.3	0.2	-0.6	-1.1	-0.5	2.1
Chronotype (morning person)	0.3	0.6	2.7	0.0	0.6	0.3	-0.1	0.8	-1.6	-0.5	1.1	-0.4
Hair Pigment	1.5	42.3	99.0	-0.3	6.0	4.1	-6.6	-8.2	5.8	9.9	-3.1	8.7
Tanning	2.2	27.0	65.6	-2.5	-4.7	-5.2	4.9	8.1	-5.2	-6.2	2.6	-5.1
Hand grip strength (left)	1.1	2.8	8.8	-2.0	1.5	1.2	-1.9	0.3	-0.7	-3.0	0.4	2.1
Number of treatments/medications taken	2.0	3.6	9.1	2.6	-1.5	-1.6	2.1	-0.4	1.7	3.0	-0.4	-2.0
Average weekly spirits intake	0.4	0.5	1.9	-1.0	0.2	-0.1	-0.5	0.6	-0.7	-0.4	-1.4	0.7
Sensitivity / hurt feelings	0.4	0.6	1.9	0.3	-0.3	0.4	0.5	-0.6	1.3	0.7	-1.4	-0.9
Frequency of depressed mood in last 2 weeks	2.1	3.0	5.7	-2.4	2.4	1.5	-2.3	0.2	-0.9	-1.3	0.3	2.4
Hearing difficulty/problems: Yes	1.6	2.5	6.1	1.9	-1.9	-1.0	2.1	-0.1	1.5	1.0	0.3	-2.5
Relative age of first facial hair	0.3	0.5	1.3	0.1	1.0	0.5	-0.9	-0.7	0.1	-0.1	-1.2	0.9
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.1	0.6	0.9	1.0	-1.0	-1.4	1.4	1.3	-1.4	1.0
Ever used hormone-replacement therapy (HRT)	0.9	1.2	3.8	1.6	-0.6	-0.7	1.1	-0.2	0.4	2.0	0.7	-1.2
Ever had hysterectomy (womb removed)	2.5	2.8	9.7	-1.4	-0.2	-1.1	0.1	2.4	-3.1	-1.0	2.4	-0.0
Systolic blood pressure, automated reading	0.6	1.6	5.9	2.4	0.6	0.7	0.4	-1.7	0.9	1.9	0.1	-0.8
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.2	0.2	-1.1	-0.7	0.9	0.4	0.1	0.3	0.4	-1.0
Angina	0.9	1.2	2.6	1.1	-1.1	-0.7	1.3	0.8	1.2	1.2	-0.0	-1.6
Medication for hormone replacement therapy	1.0	1.1	2.4	0.3	-1.3	-1.6	1.5	0.8	-0.4	0.7	0.0	-1.3
Vitamin and mineral supplements	1.1	1.5	4.5	0.4	-1.2	-2.1	1.7	1.1	0.5	0.9	0.8	-1.2
Supplements: Zinc	0.8	0.8	2.7	-1.2	0.5	0.3	-0.7	0.5	-1.6	-1.3	0.6	0.6
Medication: Co-codamol	1.3	1.5	5.2	1.1	-0.6	0.4	0.4	-1.3	2.1	0.7	-2.3	-0.5
Medication: Metformin	0.5	0.7	1.9	1.2	-0.2	0.4	0.1	-0.9	1.4	1.3	-0.5	-0.5
Diabetes (father)	0.1	0.1	0.2	-0.1	-0.4	-0.3	0.5	0.4	-0.2	-0.2	0.4	-0.4
Diabetes (mother)	4.3	5.5	12.5	3.5	-0.9	0.7	0.9	-2.5	3.3	2.7	-2.7	-1.7
Severe depression (siblings)	0.2	0.2	0.9	-0.7	0.4	-0.1	-0.3	0.2	-0.1	0.1	1.0	0.6
Pack years adult smoking proportion	1.0	1.5	4.3	0.2	1.0	1.0	-1.0	-1.7	2.1	1.3	-0.6	1.1
Impedance of leg (right)	0.4	1.8	8.3	-1.0	-1.0	-0.8	0.7	1.7	-2.9	-0.6	1.0	-0.7
Leg fat-free mass (left)	0.7	3.9	7.8	-0.3	2.8	2.2	-2.5	-1.9	1.9	-0.9	-0.8	2.6
Trunk fat percentage	0.6	2.2	4.7	-0.2	2.0	2.2	-2.0	-1.2	0.4	-1.4	-0.8	1.7
Hand grip strength (right)	1.7	4.5	9.1	-2.1	2.7	2.2	-3.0	-0.3	-0.6	-2.4	0.2	3.0
Townsend deprivation index at recruitment	0.9	1.2	2.3	0.6	-1.2	-1.3	1.5	0.2	0.8	1.3	-0.6	-1.5
Current tobacco smoking	1.3	2.1	8.8	1.1	-0.5	0.6	0.0	-1.5	1.8	1.6	-3.0	-0.2
Average weekly fortified wine intake	1.8	2.1	5.5	1.8	-1.3	-0.6	1.0	-1.3	2.0	2.4	-0.4	-0.9
Maternal smoking around birth	1.8	2.5	6.1	2.5	-0.1	1.1	0.1	-2.4	1.9	2.1	-1.2	-0.7
Fed-up feelings	2.0	3.7	7.4	-2.7	2.5	1.8	-2.7	0.1	-0.6	-1.4	-0.7	2.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	6.5	-1.4	2.5	1.6	-1.9	-0.2	-0.2	-0.7	-0.7	2.0
Relative age voice broke	0.5	0.7	1.5	0.8	0.9	0.8	-0.8	-1.0	0.5	-0.5	-1.2	0.7
Taking other prescription medications	1.4	2.2	4.7	2.0	0.9	0.9	-0.1	-1.9	1.8	2.2	-1.5	-0.1
Age when periods started (menarche)	0.3	0.7	1.9	-0.1	-0.6	-1.4	1.1	1.0	-0.9	0.7	-0.6	-0.7
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.8	-0.6	-0.5	-1.2	0.5	1.3	-1.1	-0.6	0.7	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.3	-0.5	-1.4	-1.5	1.3	1.4	-0.9	0.4	-0.1	-1.2
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.1	-0.3	1.4	1.2	-1.2	-0.4	-0.8	-1.4	0.2	1.1
Qualifications: CSEs or equivalent	0.6	0.8	3.0	-1.7	0.7	0.1	-0.7	1.1	-0.7	-0.9	-0.1	0.7
Serious illness, injury or assault to yourself	1.7	2.1	4.8	1.6	1.0	1.6	-0.5	-2.2	1.8	0.6	-1.9	-0.0
High blood pressure	1.2	3.3	9.4	3.1	-0.6	0.3	1.4	-1.9	1.9	2.2	-1.3	-2.0
Hayfever, allergic rhinitis or eczema	1.0	2.2	7.5	2.7	-1.6	-0.8	1.7	-0.5	0.9	0.9	-0.5	-2.1
Multivitamins +/- minerals	0.6	0.8	1.8	-0.9	0.5	0.9	-1.2	-0.1	-1.0	-1.3	-0.4	1.0
Stomach or abdominal pain in last month	0.4	0.5	1.8	-1.3	-0.1	-0.4	0.3	1.2	-1.0	-0.3	0.1	-0.4
Supplements: Glucosamine	0.6	0.8	2.1	0.9	1.3	1.4	-0.8	-1.0	-0.1	-0.6	-0.2	0.6
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.7	-0.5	-1.4	-1.9	1.6	1.5	-0.6	0.4	0.2	-1.2
Medication: Atenolol	0.6	0.7	1.7	-0.1	-0.6	-1.0	1.0	1.0	-0.1	0.1	-1.3	-1.1
Medication: Levothyroxine sodium	0.2	0.3	0.6	0.3	0.6	0.2	-0.4	-0.6	0.7	0.8	0.7	0.7
Sitting height	1.0	6.8	16.1	-1.9	3.5	2.8	-3.7	-1.7	0.2	-1.7	-1.7	4.0
Chronic bronchitis/emphysema (father)	0.8	0.9	5.4	0.5	-0.7	-0.5	0.5	-0.7	1.0	2.3	0.0	-0.2
High blood pressure (mother)	0.6	0.8	2.2	0.5	-0.9	-1.2	1.4	0.7	0.2	0.4	0.1	-1.5
Body mass index (BMI)	0.6	2.6	5.5	1.2	1.4	2.0	-1.2	-2.3	2.3	0.5	-1.6	0.9
Impedance of leg (left)	0.3	1.3	6.0	-1.3	-0.9	-0.7	0.4	1.6	-2.4	-0.4	0.3	-0.4
Leg predicted mass (left)	0.8	4.0	7.8	-0.3	2.8	2.2	-2.6	-1.9	2.0	-0.9	-1.0	2.6
Trunk fat mass	0.7	3.2	6.2	-0.4	2.5	2.4	-2.4	-1.5	0.8	-1.4	-0.9	2.2
Waist circumference	0.6	2.1	4.4	1.2	1.4	1.9	-1.0	-2.0	2.1	0.2	-1.6	0.5
Number of incorrect matches in round	1.3	2.1	4.3	-1.2	-1.9	-2.1	1.4	1.9	-1.4	-0.9	-0.6	-1.0
Past tobacco smoking	0.1	0.1	0.9	-0.2	-0.3	-0.0	0.0	-0.1	-0.4	-0.3	0.9	0.1
Alcohol usually taken with meals	3.2	5.1	12.9	2.8	-2.9	-2.3	3.3	0.5	0.7	-0.1	0.1	-3.6
Nervous feelings	1.7	3.2	8.8	-3.0	2.5	1.4	-2.1	0.4	-0.7	-0.9	1.1	2.2
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.1	5.8	-0.6	2.4	1.9	-2.0	-1.1	0.6	0.4	0.4	1.9
Hearing difficulty/problems with background noise	0.2	0.4	1.4	0.1	-0.1	0.3	0.6	0.1	0.6	-1.2	-0.1	-1.0
Hair/balding pattern: Pattern 2	1.2	1.5	4.2	-2.0	1.3	0.7	-1.5	0.3	-1.1	-1.2	-0.2	1.6
Had menopause	0.9	1.1	3.7	-0.0	1.4	0.8	-1.1	-0.5	-0.4	0.2	1.9	1.3
Had other major operations	1.2	1.5	6.7	-2.6	0.6	-0.1	-0.7	1.3	-1.3	-0.6	-0.8	1.2
Forced vital capacity (FVC)	0.2	0.9	3.1	-1.3	0.9	-0.1	-1.1	0.1	0.1	1.0	0.4	1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	3.6	-0.7	-1.5	-1.9	1.4	1.8	-1.2	0.3	0.8	-1.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.5	0.1	-0.8	-0.2	0.9	-0.0	0.5	0.1	-0.2	-1.2
Qualifications: None of the above	1.2	2.6	5.8	1.8	1.0	1.7	-1.0	-2.4	1.9	2.1	-1.2	0.5
Financial difficulties in last 2 years	2.4	3.2	9.1	-2.2	0.3	-0.3	-0.2	2.3	-3.0	-2.8	1.2	0.3
Mouth/teeth dental problems	2.5	3.8	12.0	-3.5	-0.2	-0.8	-0.5	2.3	-2.1	-3.2	1.0	0.8
Heart attack	4.3	5.5	12.4	1.5	-3.0	-2.9	3.5	1.3	0.8	1.7	-0.8	-3.4
Allergy	0.9	2.2	4.7	-2.2	1.4	0.7	-1.7	0.7	-0.8	-1.9	1.0	1.9
Pain all over the body in last month	1.1	1.2	4.2	0.6	-0.6	-0.4	0.3	-0.8	2.0	1.9	-1.2	-0.2
Diabetes (self-reported)	0.8	1.2	3.3	1.8	-0.4	0.6	0.3	-1.0	1.6	1.6	0.6	-0.9
Hayfever/allergic rhinitis (self-reported)	1.2	1.5	4.2	1.7	-1.4	-0.8	0.8	-0.9	1.4	2.0	-0.5	-0.8
Medication: Ramipril	0.5	0.6	1.8	0.9	-0.7	0.1	0.9	-0.2	0.6	0.9	0.1	-1.3
Medication: Simvastatin	1.6	2.4	6.0	2.4	-1.6	-0.8	1.9	-0.5	1.6	1.0	-0.1	-2.2
Fluid intelligence score	1.0	2.1	5.5	-2.1	0.4	-0.3	-0.8	1.1	-2.3	-0.7	2.0	1.5
Illnesses of siblings	2.1	2.9	7.8	-2.0	-0.3	-0.9	-0.2	2.4	-2.5	-2.8	1.1	0.5
Neuroticism score	1.1	2.3	5.0	-2.2	2.2	1.6	-2.0	0.1	-0.2	-0.8	0.2	1.9
Weight	0.8	4.1	7.9	-0.2	2.8	2.6	-2.6	-2.1	1.6	-0.7	-1.2	2.5
Impedance of arm (right)	1.2	5.6	15.7	-3.0	0.4	-0.5	-0.5	2.9	-4.0	-3.4	2.2	0.8
Arm fat percentage (right)	0.3	1.2	2.8	0.2	1.5	1.7	-1.4	-1.1	0.7	-0.9	-0.3	1.1
Trunk fat-free mass	0.6	3.2	6.4	-0.2	2.5	1.9	-2.2	-2.0	1.8	0.1	-1.0	2.4
Hip circumference	1.2	5.0	8.8	0.1	3.0	2.8	-2.7	-2.9	1.9	0.0	-1.3	2.7
Time employed in main current job	1.8	2.1	5.5	0.8	1.5	2.4	-1.5	-2.3	0.4	-0.6	-0.6	1.2
Alcohol intake versus 10 years previously	0.5	0.8	2.8	-1.1	-0.4	-0.8	0.1	1.2	-0.8	-0.6	1.7	0.1
Father’s age at death	0.5	0.7	2.1	-0.5	0.5	0.3	-0.8	0.4	-0.6	-1.3	1.4	1.0
Worrier / anxious feelings	0.2	0.4	1.0	-0.1	-0.5	-0.4	0.9	0.3	0.6	0.8	0.3	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	6.4	1.3	-0.1	-0.0	0.6	-1.2	1.7	2.5	0.2	-0.7
Falls in the last year	0.4	0.5	2.2	1.5	0.3	0.4	0.0	-0.7	0.8	0.8	-0.3	-0.3
Hair/balding pattern: Pattern 3	0.8	1.2	3.8	1.6	-0.8	-0.5	1.5	-0.1	1.1	-0.1	-0.3	-2.0
Number of live births	0.4	0.5	2.5	0.2	0.3	-0.0	0.1	0.0	-1.6	-1.0	1.0	0.0
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	4.5	-1.9	0.3	-1.1	-0.3	2.1	-1.6	-1.5	1.6	0.9
Pulse rate	4.1	7.0	16.4	1.4	-3.7	-3.5	4.0	1.3	0.5	1.6	-0.9	-3.6
Happiness	0.2	0.2	0.6	-0.3	0.4	0.8	-0.6	-0.1	0.2	-0.5	0.1	0.4
Noisy workplace	0.4	0.4	1.3	0.3	0.6	0.1	0.4	0.3	0.7	-0.9	-1.1	-0.8
Qualifications: A levels/AS levels or equivalent	1.3	2.8	7.1	-2.0	-1.1	-1.9	0.8	2.4	-1.4	-0.9	2.7	-0.1
Serious illness, injury or assault of a close relative in last 2 years	1.7	1.9	5.2	1.2	-0.8	0.3	0.4	-1.5	2.2	1.8	-2.3	-0.4
Mouth/teeth dental problems: Dentures	1.3	2.2	6.9	2.6	0.1	0.7	0.3	-2.1	1.3	2.1	-1.3	-0.6
Asthma	1.4	2.8	5.7	1.2	-2.4	-1.5	2.3	0.1	0.6	1.8	-1.1	-2.3
Medication: Ibuprofen (e.g. Nurofen)	3.7	4.8	8.2	2.4	-2.9	-2.5	2.7	-0.0	1.1	2.7	0.7	-2.5
Medication: Cholesterol lowering	1.2	1.9	4.4	2.0	-1.8	-0.9	1.7	0.1	0.9	1.0	-0.1	-2.1
Depression (self-reported)	1.4	1.7	4.0	-1.3	2.0	0.8	-1.3	0.1	-1.6	-0.7	1.3	1.5
Medication: Lansoprazole	0.4	0.5	1.5	0.9	-0.0	-0.0	0.6	0.0	1.2	0.1	-0.8	-0.9
Prospective memory result	2.4	3.0	7.7	1.8	1.1	1.9	-0.6	-2.8	1.8	0.8	-2.6	0.0
Lung cancer (father)	0.6	0.7	1.6	-0.1	1.0	1.0	-1.2	-0.8	0.5	-0.0	0.3	1.2
Illnesses of mother	4.8	5.9	10.5	-3.1	1.8	0.3	-2.0	2.1	-3.2	-3.2	2.3	2.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.9	9.1	-3.0	0.9	-0.7	-1.2	2.3	-2.2	-2.1	2.2	1.9
Pulse wave Arterial Stiffness index	2.8	3.2	10.1	3.2	-0.6	0.7	0.7	-2.3	2.3	1.4	-2.0	-1.2
Impedance of arm (left)	1.3	5.9	16.4	-3.0	0.0	-0.8	-0.2	3.2	-4.0	-3.5	2.0	0.4
Arm fat mass (right)	0.5	2.0	4.0	0.1	1.8	2.0	-1.7	-1.6	1.3	-0.5	-0.9	1.5
Trunk predicted mass	0.6	3.3	6.8	-0.3	2.6	2.0	-2.2	-2.0	1.7	0.0	-1.0	2.4
Standing height	0.6	5.8	12.6	-2.9	3.2	1.7	-3.0	0.1	-1.3	-2.6	0.4	3.5
Length of working week for main job	0.3	0.4	1.2	0.8	-0.0	0.2	0.1	-1.1	0.7	0.0	-1.0	-0.3
Exposure to tobacco smoke at home	0.4	0.4	1.1	-0.2	-0.8	-0.4	0.8	0.6	-0.9	-0.2	0.3	-1.0
Breastfed as a baby	0.1	0.1	0.3	0.6	-0.2	0.1	-0.1	0.0	-0.6	0.2	0.4	-0.1
Tense / ‘highly strung’	1.5	2.5	6.3	-1.6	2.5	2.1	-2.0	-0.8	0.2	-0.8	0.3	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	2.9	-0.1	1.6	1.4	-1.3	-1.5	1.0	0.3	-1.7	1.2
Hair/balding pattern: Pattern 4	1.5	3.7	7.8	-0.5	-1.6	-2.4	1.8	2.8	-2.0	-1.6	2.1	-1.5
Birth weight of first child	0.2	0.4	1.5	0.3	-0.1	0.7	-0.4	-0.8	1.2	0.2	-1.0	0.2
Peak expiratory flow (PEF)	0.3	0.7	2.9	0.9	-0.3	-0.4	0.5	0.5	0.5	-1.7	1.0	-0.6
Pulse wave reflection index	0.6	0.8	2.1	0.1	1.1	1.1	-1.1	-0.4	-0.6	-1.5	-0.2	0.8
Ever highly irritable/argumentative for 2 days	2.8	3.4	5.2	2.2	-2.1	-1.0	1.9	-1.2	1.8	2.3	-1.3	-2.2
Loud music exposure frequency	1.9	2.1	4.0	-1.6	1.6	1.4	-2.0	-0.1	-0.8	-1.4	-0.9	2.0
Qualifications: O levels/GCSEs or equivalent	4.6	7.4	22.5	-4.7	0.6	-1.5	-0.6	3.5	-3.7	-2.9	2.1	1.6
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	2.4	0.3	1.6	1.5	-1.2	-0.8	0.7	0.5	-0.3	1.1
Blood clot in the leg (DVT)	0.1	0.2	0.6	-0.0	0.5	0.4	0.0	-0.1	-0.7	0.7	0.1	0.0
Medication: Paracetamol	0.4	0.6	3.1	0.2	-0.5	-0.8	0.6	-0.1	-0.0	1.8	0.9	-0.6
Headache pain in last month	0.3	0.5	1.2	-0.3	-0.9	-1.1	0.8	0.8	-0.8	0.2	-0.2	-0.9
Medication for cholesterol, blood pressure or diabetes	0.9	1.4	4.3	-2.1	0.6	-0.0	-1.1	0.7	-1.1	-0.8	1.0	1.8
Glaucoma (self-reported)	0.2	0.3	0.9	-0.7	-0.2	-0.1	0.0	-0.0	0.2	-1.0	0.9	0.1
Gout (self-reported)	0.9	1.2	4.0	0.7	0.2	0.9	-0.7	-1.4	1.3	1.1	-2.0	0.4
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	2.4	-0.2	1.6	1.2	-1.4	-0.8	0.4	0.1	0.6	1.6
Medication: Amlodipine	1.2	1.7	6.6	2.6	-0.8	-0.4	1.4	-0.8	0.6	1.1	-0.4	-1.9
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.1	0.6	1.1	1.4	-0.9	-1.8	0.5	0.9	-1.7	0.8
Birth weight	1.1	2.5	8.0	-2.8	1.4	0.2	-1.4	1.1	-1.6	-1.4	1.0	1.8
Chronic bronchitis/emphysema (mother)	2.0	2.4	6.2	1.0	-1.0	0.1	0.6	-1.5	2.5	2.4	-2.1	-0.5
High blood pressure (siblings)	2.9	4.1	10.1	3.2	-0.4	0.6	1.2	-2.7	2.3	3.1	-0.3	-1.6
Forced vital capacity (FVC), Best measure	0.6	2.2	6.2	-2.3	1.5	0.2	-1.8	0.5	-0.7	-0.3	1.3	2.5
Body fat percentage	0.4	1.6	3.7	0.4	1.6	1.9	-1.6	-1.5	0.8	-0.7	-0.8	1.3
Leg fat percentage (right)	0.4	1.4	3.2	0.9	1.3	1.7	-1.2	-1.8	1.0	0.2	-0.8	1.0
Arm fat-free mass (right)	0.7	3.7	6.1	0.4	2.4	2.2	-2.2	-2.5	2.3	0.7	-1.3	2.2
Exposure to tobacco smoke outside home	0.3	0.4	1.0	-0.7	-0.8	-0.0	0.5	0.4	1.0	0.3	-0.7	-1.0
Comparative body size at age 10	0.6	1.6	4.4	1.9	0.1	1.5	-0.3	-2.1	1.9	0.1	-0.0	-0.3
Number of full brothers	0.6	0.8	2.0	-1.1	0.6	-0.6	0.1	1.4	-1.2	-1.1	0.5	0.1
Worry too long after embarrassment	0.1	0.1	0.3	-0.5	0.4	0.6	-0.5	-0.1	0.2	0.3	0.3	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.3	0.4	0.6	0.3	-0.1	-0.9	0.6	1.1	-0.7	0.2
Wheeze or whistling in the chest in last year	1.5	2.6	12.4	0.8	-0.8	0.3	0.4	-1.3	2.3	1.4	-3.5	-0.7
Number of children fathered	0.3	0.3	0.8	-0.8	0.6	-0.0	-0.4	0.1	0.2	0.9	0.6	0.7
Reason for reducing amount of alcohol drunk: Health precaution	3.3	3.9	6.7	2.4	-2.3	-0.9	2.3	-0.9	1.4	1.3	-2.6	-2.6
Age at first live birth	0.1	0.1	0.5	-0.1	-0.3	-0.1	-0.1	0.3	0.0	-0.5	0.7	0.1
Pulse wave peak to peak time	3.2	3.7	11.9	-3.5	0.9	-0.5	-1.0	2.2	-2.3	-1.6	2.0	1.6
Health satisfaction	1.1	1.4	3.3	1.6	0.2	0.3	0.5	-1.2	1.8	1.8	-1.2	-0.7
Shortness of breath walking on level ground	4.6	5.4	12.9	2.8	-0.6	0.3	1.0	-3.1	3.6	3.6	-1.8	-1.1
Qualifications: College or University degree	1.8	5.6	12.5	0.5	-3.5	-3.5	3.5	1.9	-0.1	-0.8	0.0	-2.9
Eye problems/disorders: None of the above	0.3	0.3	1.2	0.0	0.9	0.6	-0.4	-0.1	-0.2	-0.2	1.1	0.4
Mouth/teeth dental problems: Loose teeth	2.7	3.2	9.3	3.0	-0.5	0.3	1.0	-2.1	2.1	2.5	-1.1	-1.2
Emphysema/chronic bronchitis	1.8	2.0	4.6	-0.4	1.7	2.1	-2.0	-1.6	0.2	-0.2	-1.0	1.7
Medication for pain relief, constipation, heartburn	2.6	4.4	10.6	-0.9	2.7	3.2	-2.9	-1.4	-0.4	-2.2	-0.3	2.5
Neck or shoulder pain in last month	1.4	2.0	5.5	2.3	-0.8	-0.7	1.3	-1.2	1.6	1.8	-0.2	-1.5
Medication: Blood pressure	1.0	1.7	4.2	1.9	-0.8	-0.7	1.7	-0.4	0.9	1.0	-1.4	-2.1
Angina (self-reported)	0.5	0.6	1.3	1.0	-0.6	-0.2	0.8	0.6	0.9	1.0	0.3	-1.2
Migraine (self-reported)	0.9	1.1	1.9	-1.1	-0.9	-1.4	1.2	0.9	-0.6	0.8	1.4	-0.8
Medication: Ibuprofen	3.8	4.5	7.4	2.6	-2.7	-2.4	2.6	-0.0	1.1	2.4	0.9	-2.4
Medication: Allopurinol	1.2	1.6	4.0	1.7	-0.7	0.2	0.1	-1.4	2.0	2.0	-0.9	-0.4
Medication: Omeprazole	2.4	2.8	6.4	-0.5	-1.1	-2.5	2.0	2.3	-2.3	-0.2	0.7	-1.5
Medication: Seretide 50 evohaler	0.3	0.4	3.0	-0.1	0.0	0.0	-0.1	0.0	-0.1	0.2	-1.7	0.3
Mean time to correctly identify matches	1.0	1.8	3.8	-1.2	1.7	1.5	-1.5	0.0	-0.4	-1.3	-2.0	1.4
Heart disease (mother)	0.5	0.6	2.2	0.5	0.4	0.8	0.0	-1.0	1.5	0.8	-0.6	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.8	1.6	0.2	1.4	-0.4	-1.7	1.5	0.4	0.2	0.0
Whole body fat mass	0.7	3.0	5.7	0.1	2.4	2.4	-2.2	-1.9	1.4	-0.6	-1.2	2.0
Leg fat mass (right)	0.7	2.6	4.8	0.5	1.9	2.2	-1.9	-2.1	1.7	-0.1	-1.0	1.6
Arm predicted mass (right)	0.7	3.7	6.2	0.4	2.4	2.1	-2.1	-2.5	2.3	0.7	-1.6	2.1
Pulse rate, automated reading	2.0	6.4	13.4	3.1	-3.2	-2.1	3.7	-0.2	1.7	1.7	-0.1	-3.7
Alcohol intake frequency.	0.3	0.7	1.7	0.4	-0.8	-0.8	0.8	0.2	0.9	1.3	1.2	-0.7
Comparative height size at age 10	0.8	4.2	10.9	-2.6	2.7	1.4	-2.7	-0.4	-0.9	-0.9	1.3	3.3
Number of full sisters	0.2	0.3	0.9	-1.0	0.2	-0.3	-0.4	0.5	0.4	0.3	0.5	0.8
Suffer from ‘nerves’	2.5	3.9	9.3	-1.6	3.0	2.5	-2.8	-1.3	0.6	-0.8	-0.1	2.7
Overall health rating	0.7	1.5	5.0	0.6	1.0	0.4	-0.4	-1.2	2.2	2.2	-0.6	0.3
Chest pain or discomfort	0.6	0.8	3.5	0.5	-0.9	-0.2	0.8	-0.2	1.0	-0.2	-1.9	-1.1
Had major operations	0.5	0.6	2.0	-1.4	0.3	0.8	-0.9	0.5	-0.5	-0.8	0.2	0.7
Age at last live birth	1.0	1.5	3.6	0.0	-1.3	-1.0	1.2	1.2	-1.3	-0.9	1.9	-1.2
Family relationship satisfaction	0.9	1.1	2.6	-1.5	0.7	0.7	-1.0	0.7	-1.0	-1.6	1.0	1.0
Leg pain on walking	0.8	1.0	2.0	1.4	-1.1	-0.9	1.1	-0.7	1.0	1.2	-0.6	-1.0
Qualifications: NVQ or HND or HNC or equivalent	2.3	2.8	7.6	1.9	-0.4	0.7	0.1	-2.2	2.4	2.8	-1.6	-0.4
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.3	-0.2	1.1	0.7	-1.0	-1.1	0.8	1.0	-0.8	1.1
Illness, injury, bereavement, stress in last 2 years	1.3	1.5	3.6	-1.4	1.7	1.0	-1.6	-0.4	-1.0	-0.4	0.5	1.9
Medication: Aspirin	0.7	1.0	1.9	0.3	-1.3	-1.4	1.4	1.1	0.2	0.2	0.3	-1.4
Supplements: Vitamin C	1.1	1.4	4.9	0.9	1.0	2.2	-1.3	-1.6	0.5	0.0	-0.9	0.6
Knee pain experienced in last month	1.2	1.9	4.5	1.9	0.3	0.7	-0.1	-2.1	2.1	1.7	-1.0	-0.1
Hypertension (Self-reported)	1.3	3.5	9.5	3.1	-1.0	0.1	1.7	-1.8	1.6	2.1	-1.5	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.3	-0.6	-1.2	-1.5	1.2	1.8	-1.1	-0.5	-0.0	-1.2
Illnesses of father: Heart disease	0.2	0.2	0.7	0.3	0.6	0.8	-0.5	-0.5	0.5	-0.2	-0.4	0.2
Illnesses of siblings: Diabetes	1.0	1.2	2.2	-0.3	0.9	1.3	-1.5	-1.2	1.2	0.0	-1.1	1.4
Smoking status: Previous	0.1	0.2	0.6	0.8	0.4	0.2	-0.0	-0.3	0.8	0.4	-0.5	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.6	-0.1	0.4	0.8	-0.6	-0.5	-0.2	-0.7	0.4	0.6
Whole body fat-free mass	0.7	4.1	8.2	-0.3	2.9	2.2	-2.6	-2.1	1.9	-0.3	-1.1	2.7
Leg fat-free mass (right)	0.8	4.2	8.4	-0.5	2.9	2.2	-2.7	-1.8	2.1	-0.8	-1.1	2.7
Arm fat percentage (left)	0.3	1.1	2.5	0.1	1.4	1.6	-1.4	-1.0	0.7	-0.9	-0.6	1.1
Average weekly red wine intake	1.0	1.4	5.0	1.7	-0.2	0.9	-0.0	-1.5	1.4	-0.2	-2.2	-0.4
Handedness (chirality/laterality): Left-handed	0.8	0.9	2.0	0.1	-1.1	-1.4	1.2	1.1	-0.8	-0.1	0.8	-1.1
Mood swings	2.9	5.2	11.4	-2.3	3.0	2.9	-3.4	-0.4	-0.5	-1.7	-0.3	3.0
Loneliness, isolation	0.3	0.4	1.6	0.0	1.3	0.9	-0.8	-0.2	0.3	-0.4	-0.4	0.6
Long-standing illness, disability or infirmity	1.3	2.0	5.8	1.8	-0.0	-0.0	0.4	-1.3	2.4	2.2	-1.3	-0.5
Ever had bowel cancer screening	1.8	2.2	3.8	0.3	1.7	1.4	-1.2	-2.0	1.5	1.5	-1.8	1.1
Diabetes diagnosed by doctor	1.6	2.7	5.8	2.3	-1.4	-0.3	1.1	-1.0	2.3	2.4	0.6	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	3.5	1.0	-1.8	-1.2	1.7	0.9	-0.3	-0.6	0.7	-1.9
Friendships satisfaction	2.1	2.6	7.0	-2.3	0.9	0.8	-1.8	1.1	-0.6	-2.6	-1.5	1.7
Qualifications: nursing, teaching	2.6	4.1	10.2	0.3	-3.2	-2.9	2.3	2.3	-0.0	-0.2	1.5	-2.2
Commuting to job workplace: Walk	1.7	1.8	6.2	-0.0	1.2	1.2	-1.2	-0.1	-0.8	-2.0	2.5	1.0
Eye problems/disorders: Cataract	0.3	0.4	0.9	0.7	-0.8	-0.6	0.6	-0.2	0.7	0.3	-1.0	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.5	1.6	0.9	1.1	-0.6	-1.5	1.2	1.2	-0.2	0.4
Medication for cholesterol	1.8	2.8	5.8	-2.4	2.0	1.1	-2.1	0.4	-1.1	-1.6	0.5	2.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.3	1.1	0.7	0.9	-0.3	-1.2	0.2	0.2	-1.5	0.1
Back pain experienced in last month	0.5	0.7	1.6	0.2	-1.1	-1.3	0.9	0.6	0.1	0.5	1.3	-0.6
Mineral and other dietary supplements	2.2	3.0	5.8	-0.0	-2.2	-2.4	2.4	1.9	-0.1	0.4	1.3	-2.3
Breast cancer (self-reported)	0.1	0.2	0.4	-0.3	0.4	-0.0	-0.4	-0.0	0.4	0.6	0.2	0.6
Asthma (self-reported)	1.2	2.4	4.9	1.3	-2.1	-1.1	2.0	-0.2	0.7	1.7	-1.3	-2.2
Osteoporosis (self-reported)	0.6	0.8	2.7	-0.0	-1.1	-1.1	0.5	-0.3	0.9	1.6	-1.0	-0.0
Osteoarthritis (self-reported)	0.2	0.3	0.9	-0.2	0.6	0.2	-0.6	-0.2	-0.2	0.9	-0.7	0.8
Medication: Aspirin	0.7	1.0	1.8	0.8	-1.1	-1.4	1.3	0.8	0.4	0.6	0.4	-1.3
Medication: Gliclazide	0.4	0.4	2.0	-0.1	0.5	0.6	-0.4	-0.3	0.9	1.4	0.2	0.2
Illnesses of father: None of the above (group 1)	0.6	0.7	1.5	-1.0	0.3	0.4	-1.1	0.6	-0.9	-1.2	0.5	1.0
Smoking status: Current	0.7	1.1	5.8	0.5	-0.3	0.5	-0.1	-1.0	1.0	1.1	-2.4	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	4.3	-1.5	-0.1	-1.2	-0.1	2.1	-2.1	-1.5	1.4	0.6
Whole body water mass	0.6	3.5	7.2	-0.4	2.7	2.0	-2.4	-1.9	1.8	-0.3	-1.0	2.6
Leg predicted mass (right)	0.8	4.0	7.9	-0.5	2.8	2.2	-2.6	-1.8	2.1	-0.8	-1.1	2.7
Arm fat mass (left)	0.4	1.8	3.7	0.2	1.7	1.9	-1.6	-1.5	1.4	-0.5	-1.1	1.4
Number of self-reported non-cancer illnesses	0.8	1.3	4.0	1.5	-0.1	0.1	0.4	-1.0	1.2	2.0	-1.6	-0.7
Average weekly champagne plus white wine intake	2.3	3.1	6.8	-1.0	-1.3	-2.3	1.5	2.6	-2.0	-2.1	1.2	-1.2
Miserableness	1.3	2.3	5.6	-2.4	1.4	0.9	-1.6	1.1	-1.3	-1.9	0.8	1.6
Guilty feelings	1.6	2.5	6.6	-2.6	1.1	0.6	-1.3	1.4	-1.9	-1.6	1.6	1.4
Wears glasses or contact lenses	0.4	0.5	1.5	0.8	0.4	0.7	-0.2	-1.2	0.8	0.3	-0.8	0.1
Ever taken oral contraceptive pill	0.9	1.0	3.0	-0.4	-1.1	-1.7	0.8	1.7	-0.3	-0.6	0.3	-0.6
Hearing aid user	1.1	1.3	3.2	1.0	-1.6	-1.1	1.8	0.4	0.3	-0.2	0.0	-1.8
Mother’s age at death	0.3	0.4	0.9	-0.4	0.8	0.4	-0.8	0.2	-0.8	-0.5	0.4	1.0
Financial situation satisfaction	0.3	0.3	1.7	-0.3	0.3	0.8	-0.4	-0.1	0.1	-1.3	-0.5	0.0
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.5	0.3	-0.5	-0.7	1.1	0.4	0.8	-0.1	-0.9	-1.2
Commuting to job workplace: Public transport	0.5	0.6	2.4	0.6	-0.2	0.6	0.2	-0.7	0.3	-1.2	-1.5	-0.5
Eye problems/disorders: Glaucoma	1.0	1.2	2.5	-0.7	-1.5	-1.6	1.3	1.2	-0.1	-0.7	0.1	-1.2
Medication: Blood pressure	2.5	4.8	11.7	3.4	-2.1	-0.8	2.3	-1.2	1.7	2.6	-1.3	-2.9
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.2	1.0	0.2	0.0	0.2	-0.6	0.5	0.3	1.1	-0.4
Supplements: Fish oil (including cod liver oil)	2.2	2.9	6.2	-0.1	2.0	2.4	-2.5	-1.7	-0.3	-1.1	-0.6	2.4
High cholesterol (Self-reported)	0.6	1.1	4.4	2.1	-0.8	0.4	0.5	-1.1	1.0	1.0	-0.2	-1.1
Medication: Bendroflumethiazide	1.0	1.5	4.1	2.0	-1.2	-0.7	1.5	-0.6	0.4	0.8	0.8	-1.7
Medication: Paracetamol	0.3	0.4	2.2	0.2	-0.2	-0.5	0.2	-0.2	0.2	1.5	1.0	-0.2
Medication: Lisinopril	1.0	1.3	4.4	0.8	-1.3	-0.8	1.2	-0.2	0.4	2.1	1.0	-1.2
Medication: Atorvastatin	0.3	0.4	0.8	0.9	0.2	0.7	-0.3	-0.7	0.9	0.7	-0.1	-0.2
Illnesses of father: High blood pressure	1.3	1.6	3.3	-0.0	-1.0	-1.8	1.8	1.3	-1.7	-0.1	0.2	-1.5
Alcohol drinker status: Never	1.9	2.3	4.7	0.6	-2.2	-2.0	2.0	0.8	0.2	1.3	-1.3	-1.8
Ever smoked	0.2	0.4	1.6	-0.3	0.7	0.5	-0.7	0.1	0.1	-0.5	-1.3	0.5
Basal metabolic rate	0.7	3.6	7.2	-0.3	2.7	2.1	-2.4	-2.0	1.9	-0.4	-1.1	2.5
Leg fat percentage (left)	0.6	2.0	4.0	0.7	1.5	1.9	-1.5	-2.0	1.4	0.3	-1.5	1.2
Arm fat-free mass (left)	0.7	3.8	6.3	0.3	2.3	2.1	-2.1	-2.5	2.4	0.7	-1.3	2.2
Number of operations (self-reported)	2.4	3.5	10.0	-3.2	1.8	0.9	-2.0	1.1	-2.4	-1.3	-0.4	2.3
Average weekly beer plus cider intake	1.1	1.6	4.7	0.7	0.2	1.4	-0.6	-1.4	1.4	2.2	-1.6	0.3
Irritability	0.2	0.4	1.2	-0.7	0.5	0.5	-0.3	0.3	-0.5	-0.9	-1.1	0.0
Risk taking	3.7	5.5	14.3	1.9	-3.3	-2.3	3.5	0.8	0.9	1.1	0.5	-3.8
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.2	0.9	0.6	0.5	-0.2	-1.1	0.5	0.6	-0.0	0.2
Fractured/broken bones in last 5 years	1.0	1.3	3.7	0.0	-1.9	-1.4	1.5	0.6	0.3	0.6	0.9	-1.5
Age started oral contraceptive pill	0.8	1.0	2.1	0.4	1.0	1.4	-1.2	-1.4	0.9	-0.2	-0.3	1.1
Diastolic blood pressure, automated reading	0.8	2.5	5.6	1.1	2.2	2.1	-1.5	-2.4	1.2	0.8	-0.4	1.4
Ever depressed for a whole week	0.6	0.8	1.3	-0.8	-1.1	-1.1	0.9	1.1	-0.9	-0.7	0.4	-0.7
Unable to work because of sickness or disability	1.0	1.3	2.5	0.2	1.5	1.3	-1.2	-1.3	1.1	0.3	-1.6	1.0
Commuting to job workplace: Cycle	1.1	1.3	2.4	1.4	-1.2	-1.3	1.6	0.6	0.2	0.9	0.8	-1.5
Myopia	0.5	0.7	1.9	0.4	-0.9	-1.4	1.4	0.6	-0.1	-0.1	0.2	-1.2
Vascular/heart problems diagnosed by doctor	1.3	3.5	9.3	-3.0	1.0	-0.0	-1.7	1.5	-2.1	-1.9	1.4	2.4
Cholesterol lowering medication	1.0	1.5	4.5	2.1	-0.0	0.9	0.0	-1.7	2.1	0.9	-0.3	-0.5
Medication: Omeprazole (e.g. Zanprol)	2.3	2.8	7.1	-0.4	-1.4	-2.7	2.3	2.1	-1.7	0.2	0.3	-1.8
Pain experienced in last month	2.1	3.5	8.2	-2.6	0.8	-0.0	-0.5	2.2	-2.9	-2.9	1.5	0.8
Supplements: Calcium	1.1	1.2	2.6	0.5	-1.6	-1.1	1.3	0.2	0.7	1.6	-0.6	-1.2
Basal cell carcinoma (self-reported)	0.5	0.6	2.7	-0.0	-0.5	-0.6	0.5	0.1	1.1	0.8	-1.6	-0.5
Heart attack/myocardial infarction (self-reported)	4.8	6.1	13.9	1.7	-3.2	-3.0	3.7	1.4	0.9	1.8	-0.7	-3.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.8	-0.1	0.5	0.3	0.0	-0.0	-0.6	0.9	-0.1	0.1
Heart disease (siblings)	0.1	0.2	0.7	-0.3	0.2	0.1	0.0	-0.2	0.7	0.4	-0.8	0.1
Alcohol drinker status: Previous	0.7	0.8	3.6	0.3	-0.7	-1.0	0.6	0.1	1.0	1.9	0.2	-0.3
Pack years of smoking	1.0	1.5	3.5	0.4	1.2	1.1	-1.1	-1.8	1.9	1.1	-0.7	1.1
Impedance of whole body	0.7	3.8	13.3	-2.5	-0.4	-0.7	0.0	2.7	-3.6	-2.4	1.1	0.1
Leg fat mass (left)	0.8	3.0	5.2	0.4	2.1	2.3	-2.0	-2.1	1.9	-0.1	-1.3	1.8
Arm predicted mass (left)	0.7	3.4	5.5	0.2	2.2	2.0	-2.0	-2.3	2.3	0.6	-1.4	2.0