TWAS hub - TMED8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1670	0.0420	8.1e-08	0.095	NA	0.119	NA	0.122	3.4e-08	NA	5.8e-10	NA	3.5e-10
2	GTEx	Adipose Visceral Omentum	0.2020	0.0610	3.5e-05	0.028	NA	0.080	NA	0.082	1.3e-02	NA	6.2e-05	NA	4.7e-05
3	GTEx	Artery Aorta	0.1740	0.0510	1.8e-05	0.063	NA	0.093	NA	0.108	2.3e-04	NA	8.2e-06	NA	1.5e-06
4	GTEx	Artery Coronary	0.1510	0.0560	1.6e-03	0.029	NA	0.061	NA	0.063	3.6e-02	NA	4.2e-03	NA	3.8e-03
5	GTEx	Artery Tibial	0.1231	0.0453	3.3e-04	0.018	NA	0.021	NA	0.009	1.5e-02	NA	7.7e-03	NA	6.2e-02
6	GTEx	Breast Mammary Tissue	0.1840	0.0730	1.3e-03	0.042	NA	0.062	NA	0.035	3.1e-03	NA	4.3e-04	NA	6.7e-03
7	GTEx	Breast Mammary Tissue (Male)	0.2463	0.1189	1.7e-02	0.025	NA	-0.011	NA	-0.010	8.9e-02	NA	6.9e-01	NA	6.1e-01
8	GTEx	Breast Mammary Tissue (Female)	0.0915	0.0771	1.3e-01	0.026	NA	0.030	NA	0.030	5.6e-02	NA	4.5e-02	NA	4.5e-02
9	GTEx	Cells Transformed fibroblasts	0.1950	0.0460	5.3e-09	0.211	NA	0.163	NA	0.187	8.7e-16	NA	2.9e-12	NA	5.4e-14
10	GTEx	Colon Sigmoid	0.1820	0.0700	1.5e-03	0.072	NA	0.073	NA	0.124	1.6e-03	NA	1.4e-03	NA	3.8e-05
11	GTEx	Esophagus Mucosa	0.2340	0.0490	8.9e-11	0.086	NA	0.124	NA	0.143	2.1e-06	NA	1.2e-08	NA	8.6e-10
12	GTEx	Esophagus Muscularis	0.0970	0.0420	4.2e-03	0.081	NA	0.022	NA	0.075	1.2e-05	NA	1.7e-02	NA	2.6e-05
13	GTEx	Heart Atrial Appendage	0.1340	0.0570	4.8e-03	0.201	NA	0.146	NA	0.196	2.1e-09	NA	4.3e-07	NA	3.6e-09
14	GTEx	Lung	0.1643	0.0363	5.3e-10	0.157	NA	0.169	NA	0.164	4.3e-12	NA	6.3e-13	NA	1.4e-12
15	GTEx	Muscle Skeletal	0.0701	0.0280	2.5e-03	0.019	NA	0.026	NA	0.008	4.7e-03	NA	1.3e-03	NA	5.3e-02
16	GTEx	Nerve Tibial	0.2708	0.0515	2.2e-12	0.198	NA	0.284	NA	0.277	5.2e-14	NA	2.7e-20	NA	9.3e-20
17	GTEx	Skin Not Sun Exposed Suprapubic	0.1970	0.0620	5.1e-04	0.061	NA	0.066	NA	0.073	2.9e-04	NA	1.7e-04	NA	8.2e-05
18	GTEx	Skin Sun Exposed Lower leg	0.1510	0.0360	3.6e-08	0.117	NA	0.142	NA	0.155	6.7e-10	NA	7.7e-12	NA	8.4e-13
19	GTEx	Spleen	0.3030	0.0970	7.9e-04	0.074	NA	0.144	NA	0.151	5.9e-03	NA	1.6e-04	NA	1.1e-04
20	GTEx	Stomach	0.1360	0.0570	4.7e-03	0.069	NA	0.122	NA	0.128	3.2e-04	NA	2.0e-06	NA	1.1e-06
21	GTEx	Testis	0.2260	0.0740	1.2e-03	0.017	NA	0.050	NA	0.037	5.9e-02	NA	2.9e-03	NA	9.3e-03
22	GTEx	Whole Blood	0.1360	0.0390	1.2e-06	0.091	NA	0.067	NA	0.043	1.0e-08	NA	8.1e-07	NA	7.7e-05
23	TCGA	Breast Invasive Carcinoma	0.0191	0.0115	8.4e-03	0.009	0.003	0.003	NA	0.003	3.9e-03	0.06000	5.6e-02	NA	5.5e-02
24	TCGA	Kidney Renal Clear Cell Carcinoma	0.0303	0.0171	6.8e-03	0.023	0.015	0.008	NA	0.013	1.2e-03	0.00670	4.1e-02	NA	1.0e-02
25	TCGA	Brain Lower Grade Glioma	0.0759	0.0416	6.2e-04	0.043	0.026	0.037	NA	0.030	1.2e-05	0.00054	4.3e-05	NA	2.2e-04
26	TCGA	Thyroid Carcinoma	0.0340	0.0180	3.4e-03	0.041	0.033	0.029	NA	0.026	6.5e-05	0.00033	6.6e-04	NA	1.3e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26
Irritability	4.9	8.2	14.0	3.1	2.9	3.5	3.3	2.8	2.7	2.5	3.1	3.5	3.2	3.0	2.9	3.3	3.2	3.3	3.4	3.6	2.7	3.7	1.1	2.4	2.6	1.9	2.2	1.5
Medication: Ventolin 100micrograms inhaler	4.6	5.9	12.4	2.3	2.4	2.7	0.6	3.5	2.7	3.3	2.2	3.0	2.9	2.2	2.2	3.0	2.3	2.2	3.0	2.4	3.5	2.8	-0.4	3.3	1.2	1.0	1.5	2.0
Birth weight	4.3	9.4	13.9	3.4	3.2	3.6	2.6	3.2	3.6	3.7	3.0	2.8	3.7	3.3	3.0	3.6	3.6	3.7	3.4	3.7	3.6	2.8	0.9	3.2	3.2	1.5	2.0	1.6
Hand grip strength (right)	4.2	11.5	19.5	-4.2	-3.7	-3.2	-3.7	-2.9	-3.0	-2.0	-3.9	-3.7	-3.5	-4.0	-3.8	-2.5	-4.1	-4.4	-3.0	-4.1	-2.0	-4.4	-3.5	-1.9	-3.9	-3.7	-2.7	-2.4
Tense / ‘highly strung’	4.0	6.6	10.0	2.8	3.0	3.2	1.6	2.2	3.0	2.9	2.9	2.8	2.9	2.6	2.8	2.6	2.8	2.7	2.9	2.9	1.9	3.1	1.4	2.3	2.3	2.3	2.6	1.8
Triglycerides	3.8	6.2	10.7	2.6	3.3	2.3	0.7	2.5	2.4	3.0	3.0	2.6	2.8	2.6	2.9	2.3	2.7	2.8	2.7	2.8	2.1	3.3	2.1	2.5	1.8	2.5	0.5	2.4
Blood White Count	3.8	27.9	80.5	5.1	4.8	6.1	2.8	7.2	6.8	7.5	3.4	3.7	6.2	3.2	3.3	7.7	4.8	5.2	5.1	5.6	9.0	3.7	1.3	7.8	3.3	3.0	4.9	5.0
Number of operations (self-reported)	3.8	5.6	11.2	-2.8	-3.0	-2.3	-1.3	-2.1	-1.9	-2.2	-3.2	-2.8	-2.5	-3.2	-3.4	-2.1	-2.8	-3.0	-3.0	-2.7	-1.5	-3.1	-0.3	-1.5	-2.2	-1.5	-2.0	-0.5
Exposure to tobacco smoke outside home	3.5	4.7	11.8	2.6	1.9	2.4	3.4	2.2	2.4	1.6	2.0	2.4	2.6	2.3	1.9	2.5	2.5	2.1	1.6	2.2	1.4	2.2	1.6	1.6	2.6	2.0	1.2	2.6
Tinnitus: Yes, now most or all of the time	3.5	4.1	8.9	-2.3	-1.8	-2.5	-2.3	-1.4	-2.8	-2.2	-1.8	-1.0	-2.3	-1.8	-1.6	-2.4	-2.3	-1.9	-2.0	-1.9	-2.1	-1.2	-3.0	-1.9	-2.1	-2.4	-1.5	-2.0
Qualifications: None of the above	3.4	7.3	22.2	3.1	3.0	2.8	1.0	2.7	1.9	1.7	3.7	4.7	2.6	3.6	3.7	1.8	3.2	3.2	3.3	4.1	1.0	3.7	1.0	1.1	2.4	1.3	1.8	0.6
Hand grip strength (left)	3.3	8.7	16.7	-3.5	-3.2	-2.8	-3.7	-3.3	-2.1	-1.3	-3.2	-3.4	-3.0	-3.3	-3.2	-2.3	-3.3	-4.0	-2.3	-3.6	-2.2	-4.1	-2.5	-1.8	-3.2	-3.5	-1.8	-2.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.3	3.9	6.7	-2.1	-2.6	-2.0	-2.1	-2.6	-1.7	-0.8	-2.4	-1.5	-2.0	-2.3	-2.4	-2.0	-2.3	-2.2	-2.3	-2.5	-1.9	-2.3	-1.5	-1.4	-1.5	-2.2	-1.0	-1.5
Blood Eosinophil Count	3.1	24.2	39.1	5.1	4.5	5.4	4.7	6.2	6.1	5.8	4.0	4.5	5.9	4.0	4.1	6.0	4.9	5.0	5.0	4.6	5.6	5.3	3.3	5.8	4.3	4.6	2.4	6.3
Had other major operations	3.0	3.6	7.5	-2.1	-2.4	-1.6	-0.0	-2.1	-0.9	-1.7	-2.6	-2.6	-1.8	-2.4	-2.7	-1.5	-2.2	-2.2	-2.7	-2.5	-1.4	-2.5	-0.8	-1.1	-1.4	-1.2	-2.2	-0.2
Peak expiratory flow (PEF)	3.0	7.0	13.5	-2.8	-2.8	-2.3	-3.3	-2.6	-3.1	-1.9	-2.7	-2.7	-2.6	-2.6	-2.7	-2.3	-2.7	-3.0	-2.2	-2.5	-1.0	-3.4	-3.7	-1.7	-2.4	-3.2	-2.0	-3.5
Age when periods started (menarche)	2.9	6.9	12.0	2.9	2.3	2.6	1.7	3.5	3.1	3.1	2.3	2.7	2.9	2.6	2.3	3.0	2.9	2.5	2.7	2.5	3.0	2.3	2.0	2.6	2.8	2.9	3.0	2.4
Qualifications: O levels/GCSEs or equivalent	2.9	4.6	13.6	-2.1	-2.3	-2.4	-0.9	-2.9	-1.1	-1.1	-2.8	-3.7	-2.1	-2.7	-2.9	-1.6	-2.3	-2.2	-2.7	-2.5	-1.9	-3.0	-1.5	-1.0	-1.3	-1.4	-1.9	-1.3
Number of incorrect matches in round	2.8	4.6	10.8	-2.6	-2.3	-2.9	-3.3	-1.4	-0.9	-1.2	-2.5	-1.8	-2.7	-2.7	-2.5	-2.2	-2.8	-2.8	-2.7	-2.7	-1.7	-1.4	-0.9	-1.9	-2.3	-1.3	-1.1	-0.5
Comparative height size at age 10	2.8	15.6	26.8	-4.1	-4.1	-4.4	-3.7	-4.2	-4.5	-4.5	-3.7	-3.6	-4.8	-3.8	-3.8	-4.9	-4.2	-4.6	-3.6	-3.9	-3.9	-4.4	-2.4	-4.6	-3.2	-3.4	-1.7	-5.2
Back pain experienced in last month	2.8	4.0	15.5	-2.0	-1.7	-2.5	-0.4	-1.9	-3.1	-3.9	-0.4	-1.0	-2.7	-0.7	-0.6	-3.1	-1.7	-1.6	-1.2	-1.0	-3.6	-0.9	0.3	-3.8	-1.8	-0.1	-1.9	-1.3
Lung cancer (father)	2.7	3.1	7.2	-1.9	-2.2	-2.4	-0.6	-1.6	-1.3	-2.2	-2.0	-1.2	-2.3	-1.9	-2.0	-2.7	-2.0	-1.7	-2.1	-2.1	-2.2	-1.6	-1.4	-2.1	-1.4	-0.9	0.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.7	14.1	-2.8	-2.5	-2.8	-2.7	-2.0	-3.8	-3.1	-1.8	-1.9	-3.0	-2.0	-1.9	-2.8	-2.6	-2.3	-1.7	-2.0	-2.2	-2.5	-2.0	-3.2	-2.5	-1.5	-0.9	-2.5
Frequency of tenseness / restlessness in last 2 weeks	2.6	4.0	8.2	2.1	2.7	2.4	0.9	1.5	2.6	1.7	2.6	2.6	2.2	2.4	2.5	1.7	2.4	2.2	2.3	2.5	0.9	2.9	1.0	1.5	1.6	1.1	1.1	1.4
Forced expiratory volume in 1-second (FEV1)	2.6	8.7	15.9	-3.2	-2.8	-3.3	-4.0	-2.9	-3.6	-2.6	-2.6	-3.3	-3.4	-2.6	-2.6	-3.2	-3.0	-3.1	-2.2	-2.6	-2.0	-3.2	-3.3	-2.7	-2.8	-3.4	-1.9	-4.0
Crohns Disease (2017)	2.5	5.4	11.4	-2.2	-2.6	-2.9	-1.7	-2.2	-2.5	-2.6	-1.8	-1.8	-2.8	-2.0	-1.8	-3.3	-2.2	-2.3	-2.4	-2.2	-2.7	-3.4	-0.8	-3.0	-1.8	-2.0	-1.2	-3.1
Alcohol intake frequency.	2.5	5.9	12.1	2.8	2.6	2.7	2.5	2.7	1.2	1.0	3.5	2.8	2.6	3.3	3.3	1.8	3.1	3.2	2.9	3.2	1.4	2.3	1.8	1.4	2.1	2.4	1.6	0.8
Pain experienced in last month	2.4	4.0	12.8	2.4	2.2	2.3	1.0	1.8	2.6	3.6	1.6	0.9	2.7	1.8	1.7	2.4	2.3	2.0	2.2	1.7	2.2	1.0	1.8	2.9	2.0	0.8	0.9	1.1
Average weekly beer plus cider intake	2.3	3.4	6.2	2.2	1.7	2.2	1.8	1.0	2.2	2.1	1.3	2.2	2.5	1.6	1.2	2.3	2.2	1.9	1.6	1.8	1.4	2.1	0.2	2.2	2.4	1.4	1.5	1.6
Heart disease (siblings)	2.3	2.8	5.5	-1.9	-1.8	-1.7	-1.1	-1.4	-2.2	-1.9	-1.3	-1.1	-2.0	-1.4	-1.2	-1.9	-1.7	-1.4	-1.2	-1.5	-2.0	-1.4	-2.1	-2.3	-1.4	-2.1	-1.8	-1.9
Number of full sisters	2.2	2.7	6.0	-1.8	-2.5	-1.5	-0.7	-1.0	-1.2	-2.0	-2.3	-1.7	-1.8	-2.0	-2.2	-1.4	-1.9	-1.4	-2.4	-1.7	-1.1	-2.1	-1.4	-1.4	-1.4	-1.7	-0.0	-0.5
Smoking status: Previous	2.2	3.3	9.7	-2.3	-2.3	-1.2	-3.1	-0.6	-0.9	-0.0	-2.2	-0.6	-1.2	-2.4	-2.2	-0.8	-2.2	-2.8	-1.6	-2.6	0.1	-1.9	-1.3	0.2	-2.3	-1.6	-2.9	-0.1
Depressed Affect (Nagel 2018)	2.1	4.4	8.2	1.9	2.6	2.2	1.7	2.9	2.5	1.7	2.3	2.3	2.2	2.1	2.2	2.3	2.1	2.1	2.4	2.5	1.6	2.6	0.7	2.2	0.9	1.8	1.9	2.5
Ever had hysterectomy (womb removed)	2.1	2.4	6.2	-1.3	-1.3	-1.0	-1.3	-2.4	-1.4	-1.0	-1.0	-0.6	-1.2	-1.0	-0.8	-1.5	-1.1	-1.8	-1.1	-1.2	-2.5	-2.2	-1.8	-1.7	-1.1	-2.5	-2.0	-2.1
Fed-up feelings	2.1	3.9	7.7	1.9	2.4	1.9	1.7	2.2	1.8	0.9	2.5	2.2	1.9	2.2	2.4	1.5	2.0	2.4	2.2	2.3	0.7	2.8	1.3	1.5	1.2	2.0	2.4	2.3
Multivitamins +/- minerals	2.1	2.7	4.7	-2.0	-1.8	-1.6	-1.2	-1.7	-1.7	-1.5	-2.1	-1.9	-1.6	-2.0	-2.1	-1.1	-1.9	-1.9	-1.9	-2.2	-1.3	-2.2	-1.3	-1.0	-1.7	-1.6	-1.5	-0.4
Illnesses of siblings: Diabetes	2.1	2.6	6.5	1.9	1.5	1.9	2.5	1.1	1.2	0.8	2.0	0.8	1.6	2.0	2.0	1.4	1.9	2.3	2.0	1.9	0.6	2.2	1.1	0.7	1.7	1.4	1.1	1.0
Mood swings	2.1	3.8	8.2	1.5	2.0	2.1	1.0	2.6	2.0	1.8	2.4	2.9	2.2	2.0	2.2	2.3	1.8	1.9	2.8	2.3	1.9	2.5	0.5	1.8	0.3	1.2	1.4	2.0
Long-standing illness, disability or infirmity	2.1	3.2	5.9	-1.9	-2.4	-2.1	-0.7	-1.9	-1.6	-2.2	-1.9	-1.3	-2.1	-1.8	-1.9	-2.2	-1.9	-2.1	-1.9	-1.9	-2.2	-2.1	-1.1	-2.2	-1.4	-1.2	-0.9	-1.2
Crohns Disease (2012)	2.0	3.2	5.4	-1.8	-2.0	-2.0	-1.8	-1.4	-2.3	-2.2	-1.4	-0.9	-2.0	-1.6	-1.4	-2.2	-1.8	-1.8	-1.6	-1.7	-1.8	-2.2	-1.7	-2.0	-1.6	-2.1	-0.9	-2.3
Number of live births	2.0	2.8	5.3	-2.2	-1.9	-2.0	-2.0	-0.7	-1.9	-2.3	-1.6	-1.2	-2.1	-1.7	-1.7	-2.0	-2.1	-1.8	-1.7	-1.7	-0.8	-2.0	-0.9	-1.9	-1.9	-1.4	-0.5	-0.4
Health satisfaction	2.0	2.6	4.4	-1.9	-1.5	-2.1	-1.5	-1.5	-1.5	-2.0	-1.6	-1.5	-2.1	-1.7	-1.5	-2.0	-1.9	-1.7	-1.5	-1.9	-1.8	-1.0	-1.2	-1.6	-1.8	-1.1	-1.7	-1.1
Neck or shoulder pain in last month	2.0	2.9	6.1	-1.7	-1.4	-1.6	-1.8	-2.4	-2.0	-1.6	-1.2	-0.5	-1.8	-1.3	-1.1	-2.0	-1.5	-2.1	-1.4	-1.8	-2.5	-1.1	-1.9	-2.0	-1.5	-1.8	-2.1	-2.1
Other serious medical condition/disability diagnosed by doctor	1.9	2.4	4.8	-1.6	-2.1	-1.8	-1.3	-1.1	-2.0	-2.0	-1.5	-1.1	-1.6	-1.6	-1.5	-1.6	-1.6	-2.2	-0.9	-1.5	-1.4	-2.0	-1.8	-1.3	-1.5	-1.6	-0.1	-1.6
Angina	1.9	2.5	9.3	-1.8	-1.6	-2.0	-1.1	-1.1	-1.2	-2.6	-0.8	-0.2	-2.2	-1.0	-0.9	-3.0	-1.6	-1.5	-1.0	-1.2	-2.4	-1.2	0.3	-3.1	-1.6	-0.3	-0.1	-0.8
Had major operations	1.9	2.3	7.3	-1.6	-1.8	-1.1	-0.8	-1.1	-0.3	-0.3	-2.6	-2.4	-1.3	-2.6	-2.7	-0.2	-1.9	-1.5	-2.1	-1.4	0.5	-2.3	-0.6	-0.0	-1.3	-1.1	-0.4	0.1
Mineral and other dietary supplements	1.9	2.5	4.6	1.6	2.1	1.3	1.3	1.6	1.9	1.3	2.1	1.8	1.5	1.9	2.1	1.3	1.7	2.1	1.6	1.9	0.7	2.1	0.9	1.0	1.0	1.4	2.1	0.6
Medication: Atorvastatin	1.9	2.3	7.8	-1.9	-1.5	-1.5	-2.8	-1.6	-0.4	-0.5	-1.5	-0.4	-1.6	-1.6	-1.5	-1.6	-1.6	-1.3	-1.4	-1.6	-0.7	-1.5	-2.0	-0.9	-1.7	-2.1	-1.2	-2.0
Ever smoked	1.9	3.3	8.2	-2.1	-1.7	-0.7	-2.9	-0.4	-0.1	0.9	-2.4	-1.1	-0.6	-2.4	-2.3	0.4	-1.9	-2.4	-1.4	-2.2	1.3	-2.1	-2.6	1.2	-2.4	-2.4	-2.8	0.2
Supplements: Glucosamine	1.8	2.4	5.7	-1.7	-2.4	-1.8	0.3	-1.3	-1.3	-1.1	-2.3	-1.5	-1.8	-2.3	-2.4	-1.4	-1.9	-1.7	-1.5	-1.6	-0.5	-2.0	-0.1	-1.2	-1.2	-0.9	-1.6	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.8	17.0	-2.8	-2.3	-2.7	-4.1	-1.7	-2.9	-1.8	-2.2	-2.4	-2.7	-2.3	-2.2	-2.4	-2.6	-2.8	-1.8	-2.2	-1.2	-2.4	-2.3	-1.9	-2.7	-2.5	-1.6	-3.0
Irritable Bowel Disease (IBD)	1.7	4.0	9.1	-2.0	-2.1	-2.5	-2.0	-2.0	-2.3	-2.4	-1.2	-1.5	-2.5	-1.5	-1.4	-3.0	-1.9	-2.0	-1.8	-1.9	-2.7	-2.5	-0.5	-2.8	-1.7	-1.3	-1.0	-2.4
Past tobacco smoking	1.7	3.2	11.3	2.1	1.9	0.7	3.2	0.2	0.4	-0.7	2.2	0.2	0.7	2.3	2.1	-0.1	1.9	2.6	1.4	2.3	-1.1	1.7	1.9	-1.0	2.3	2.3	3.4	0.0
Diabetes (self-reported)	1.7	2.6	7.8	-1.5	-1.7	-2.0	-0.3	-1.5	-1.2	-2.3	-1.5	-1.5	-2.3	-1.4	-1.6	-2.7	-1.6	-1.1	-2.2	-1.4	-2.1	-1.4	-0.5	-2.8	-0.7	-0.2	-0.3	-0.5
Angina (self-reported)	1.7	2.3	9.6	-1.8	-1.5	-1.9	-1.0	-1.0	-1.3	-2.6	-0.6	-0.2	-2.1	-0.9	-0.7	-2.9	-1.5	-1.4	-0.8	-1.1	-2.3	-1.2	0.5	-3.1	-1.6	-0.3	-0.0	-0.7
Type 2 Diabetes (T2D) (2012)	1.6	1.8	6.6	-1.5	-1.3	-0.9	0.5	-1.7	-1.7	-2.6	-1.2	-0.6	-1.7	-1.3	-0.5	-1.9	-1.7	-0.4	-0.7	-1.0	-2.0	-1.5	-0.7	-2.4	-0.4	-0.2	0.7	-1.4
Financial difficulties in last 2 years	1.6	2.2	4.0	-1.5	-1.9	-2.0	-0.5	-0.8	-1.7	-1.6	-1.8	-1.1	-2.0	-1.9	-1.9	-1.3	-1.8	-1.4	-1.4	-0.9	-0.7	-1.6	-1.7	-1.5	-1.4	-1.0	1.4	-1.0
Overall health rating	1.6	3.4	12.1	-1.3	-2.0	-2.4	-0.5	-2.5	-1.1	-2.8	-1.7	-1.3	-2.4	-1.7	-1.6	-2.6	-1.7	-1.7	-2.3	-1.5	-3.5	-1.4	-0.6	-2.7	-0.7	-0.7	-0.1	-1.1
Type 2 Diabetes (T2D) (2018)	1.5	2.9	6.2	-1.9	-1.8	-1.9	-1.1	-1.7	-1.7	-2.4	-1.7	-1.5	-2.4	-1.7	-1.7	-2.4	-2.0	-1.4	-2.1	-1.4	-1.6	-1.4	-0.7	-2.5	-1.5	-0.8	-0.7	-1.5
Vitamin and mineral supplements	1.5	2.1	4.1	1.9	1.5	1.4	1.4	1.0	1.4	0.8	1.9	1.8	1.2	1.8	2.0	0.7	1.7	1.9	1.6	1.9	0.4	2.0	0.7	0.1	1.6	0.9	2.0	-0.4
Supplements: Zinc	1.5	1.7	5.7	-0.7	-1.0	-1.2	0.5	-1.3	-1.0	-1.2	-1.4	-1.6	-0.9	-1.0	-1.3	-1.3	-0.9	-1.2	-2.0	-1.8	-2.0	-1.6	-1.5	-1.2	-0.2	-1.0	-2.4	-0.2
Time employed in main current job	1.5	1.7	5.1	1.2	2.1	0.6	1.9	1.7	1.2	1.0	1.5	0.5	1.0	1.4	1.5	0.8	1.2	1.8	1.0	1.1	0.7	2.3	-0.2	0.7	0.9	1.9	1.0	1.6
Commuting to job workplace: Walk	1.5	1.7	4.9	-1.1	-1.6	-1.1	-0.8	-0.9	-0.3	-0.0	-2.1	-1.8	-1.1	-2.1	-2.1	-0.3	-1.5	-1.7	-1.9	-1.8	-0.6	-2.2	0.7	0.0	-0.9	0.3	-0.3	1.0
Cholesterol lowering medication	1.5	2.3	8.8	-0.8	-1.6	-1.2	0.2	-2.5	-1.7	-2.3	-0.9	-0.7	-1.7	-0.7	-0.8	-2.4	-0.8	-0.9	-1.5	-0.7	-3.0	-1.5	-0.4	-2.5	0.1	-1.0	-0.5	-2.4
Chronotype (morning person)	1.4	3.2	9.1	-1.8	-1.5	-1.4	-3.0	-1.9	-2.2	-1.8	-1.4	-1.2	-1.7	-1.4	-1.3	-1.7	-1.7	-2.7	-1.6	-2.4	-1.7	-1.4	-0.9	-1.2	-1.7	-2.2	-1.9	-2.1
Ever unenthusiastic/disinterested for a whole week	1.4	1.7	4.6	-1.7	-0.9	-1.0	-1.0	-1.1	-1.3	-0.9	-1.2	-1.4	-1.3	-1.5	-1.3	-1.0	-1.6	-1.7	-0.7	-1.4	-0.9	-0.8	-1.4	-0.5	-2.0	-2.1	-2.1	0.0
Forced vital capacity (FVC), Best measure	1.4	5.2	15.2	-2.7	-2.1	-2.6	-3.9	-1.7	-2.8	-1.8	-2.1	-2.2	-2.5	-2.1	-2.1	-2.3	-2.4	-2.6	-1.8	-2.0	-1.1	-2.3	-2.2	-1.9	-2.5	-2.4	-1.9	-3.0
Migraine (self-reported)	1.4	1.7	4.8	0.9	1.7	1.8	0.2	1.6	0.7	0.8	1.8	1.9	1.5	1.7	1.8	1.5	1.2	0.8	1.4	1.1	0.6	2.2	0.8	1.1	0.1	1.1	-0.6	1.5
Loneliness, isolation	1.4	1.9	5.4	1.6	1.7	1.6	1.1	1.0	2.2	2.2	1.2	0.5	1.8	1.0	1.3	2.3	1.4	1.0	1.2	1.4	0.8	1.1	0.6	1.9	0.8	1.2	0.7	1.7
Neuroticism (Nagel 2018)	1.3	3.1	5.5	1.6	2.2	1.9	1.1	2.3	2.3	1.8	2.0	2.0	1.7	1.8	1.9	1.7	1.7	1.7	1.9	2.1	1.3	2.3	0.5	1.7	0.9	1.8	1.5	2.0
Bipolar Disorder (2011)	1.3	1.2	5.4	0.8	1.3	1.6	0.7	1.4	0.8	1.3	0.9	1.2	1.4	0.9	0.9	1.7	1.0	0.5	0.9	0.8	0.9	0.6	-0.7	1.4	0.5	1.1	0.9	2.3
Lupus	1.3	2.0	7.3	-1.8	-0.9	-1.0	-2.7	-1.5	-0.9	-0.5	-1.3	-0.8	-1.2	-1.4	-1.2	-0.6	-1.6	-2.1	-0.6	-1.4	-0.2	-1.8	-1.8	-0.5	-2.2	-1.7	-2.0	-1.0
Primary Biliary Cirrhosis	1.3	1.8	4.0	-1.4	-1.2	-1.9	-1.5	-1.2	-1.3	-1.4	-1.2	-1.3	-2.0	-1.3	-1.2	-1.7	-1.6	-1.1	-1.5	-1.0	-1.3	-1.3	-1.1	-1.8	-1.5	-0.7	-0.9	-1.1
Relative age of first facial hair	1.3	2.7	7.0	1.3	1.9	1.6	-0.5	1.7	2.2	2.6	1.3	1.7	2.0	1.3	1.3	2.6	1.4	1.3	1.9	2.1	2.4	1.9	-0.3	2.5	0.2	0.0	0.9	0.6
Medication: Atenolol	1.3	1.6	6.3	-1.0	-1.5	-1.0	-1.2	-1.9	-0.8	-0.8	-1.0	0.0	-1.2	-0.9	-0.9	-1.3	-1.0	-0.7	-0.8	-1.1	-1.5	-1.2	-1.9	-1.5	-0.8	-2.3	-0.3	-2.5
Forced vital capacity (FVC)	1.3	5.1	11.3	-2.5	-2.0	-2.6	-3.3	-2.1	-2.7	-1.9	-1.9	-2.6	-2.6	-1.9	-2.0	-2.6	-2.2	-2.3	-1.7	-1.9	-1.4	-2.4	-2.4	-2.1	-2.1	-2.5	-1.4	-3.4
Trunk fat-free mass	1.3	7.5	13.0	-3.1	-3.1	-3.0	-1.5	-2.2	-2.6	-2.8	-2.9	-3.3	-3.6	-3.0	-3.1	-3.2	-3.1	-2.9	-2.8	-2.4	-2.5	-2.9	-2.6	-3.0	-2.6	-2.8	-1.6	-2.3
Trunk predicted mass	1.3	7.6	13.0	-3.1	-3.1	-3.1	-1.5	-2.2	-2.5	-2.8	-3.0	-3.4	-3.6	-3.1	-3.1	-3.2	-3.1	-2.9	-2.9	-2.5	-2.5	-2.9	-2.6	-3.0	-2.7	-2.8	-1.7	-2.2
Eye problems/disorders: None of the above	1.3	1.5	7.1	-1.2	-0.6	-1.0	-2.7	-1.2	-1.4	-0.4	-1.2	-0.9	-1.0	-1.4	-1.1	-0.5	-1.3	-1.7	-1.4	-1.6	-0.6	-1.1	-1.3	0.1	-1.3	-1.5	-0.9	-1.5
Blood Red Count	1.2	11.7	28.3	4.9	2.5	4.0	5.3	2.1	3.7	1.4	3.3	3.5	3.4	3.8	3.5	1.9	4.4	4.5	3.0	4.2	0.8	3.3	2.8	1.1	5.2	3.7	3.7	1.6
Tanning	1.2	14.7	27.4	4.3	3.9	4.4	3.1	3.6	5.2	4.6	3.5	3.9	4.4	3.8	3.5	4.2	4.2	4.2	3.2	4.1	3.5	4.0	3.6	3.4	3.7	3.6	3.8	3.2
Number of treatments/medications taken	1.2	2.2	5.7	-1.6	-1.9	-1.6	-0.4	-1.6	-2.0	-2.0	-1.2	-0.7	-2.0	-1.2	-1.3	-2.0	-1.6	-1.6	-1.1	-1.3	-2.1	-1.4	-1.1	-2.4	-1.0	-1.1	-0.2	-1.6
Falls in the last year	1.2	1.7	4.6	1.5	0.9	0.9	2.0	0.4	0.2	-1.0	1.8	1.3	1.0	1.8	1.9	0.3	1.5	1.2	1.4	0.9	-0.8	1.8	1.7	-0.8	1.4	2.2	-0.7	1.1
Birth weight of first child	1.2	2.2	5.5	2.0	1.1	1.1	2.2	1.1	1.3	1.0	1.2	2.3	1.6	1.5	1.3	1.4	1.8	2.0	1.7	1.8	1.1	0.8	-0.3	0.8	2.2	0.4	2.1	-0.2
Arm predicted mass (right)	1.2	6.1	10.8	-2.9	-2.9	-2.8	-0.9	-1.9	-2.2	-2.9	-2.7	-2.9	-3.3	-2.8	-2.8	-3.0	-2.8	-2.5	-2.5	-2.3	-2.2	-2.3	-2.1	-2.7	-2.4	-2.4	-1.4	-1.8
Diabetes diagnosed by doctor	1.2	2.0	6.7	-1.2	-1.5	-1.7	-0.1	-1.7	-0.9	-2.0	-1.3	-0.9	-2.0	-1.2	-1.3	-2.6	-1.3	-1.0	-1.9	-1.0	-2.0	-1.2	-0.1	-2.6	-0.5	-0.6	-0.0	-1.2
Eye problems/disorders: Cataract	1.2	1.3	5.3	0.9	0.4	1.0	2.2	1.1	1.6	1.4	0.7	0.1	0.9	0.8	0.5	0.8	0.9	1.4	0.9	1.2	0.9	0.3	1.1	0.4	0.8	1.8	1.6	2.3
Medication: Bendroflumethiazide	1.2	1.8	7.6	1.4	0.7	1.0	2.8	1.0	0.8	-0.6	1.7	0.9	0.9	1.7	1.6	0.1	1.5	1.6	1.4	1.7	-0.5	0.8	1.7	-0.7	1.7	1.3	2.1	1.1
Illnesses of father: High blood pressure	1.2	1.5	4.4	-1.1	-1.5	-1.0	0.2	-1.1	-0.3	-0.5	-1.7	-2.1	-1.0	-1.7	-1.8	-0.4	-1.3	-1.7	-1.9	-1.2	-0.8	-2.1	-0.7	-0.4	-0.8	-0.3	0.4	1.1
Arm fat-free mass (left)	1.2	6.0	10.2	-2.7	-2.9	-2.7	-0.6	-2.1	-2.1	-2.8	-2.6	-2.9	-3.2	-2.7	-2.8	-3.0	-2.7	-2.6	-2.5	-2.2	-2.5	-2.6	-2.0	-2.8	-2.1	-2.4	-1.2	-2.1
Unable to work because of sickness or disability	1.2	1.5	4.2	1.3	1.2	0.8	1.0	0.8	2.0	0.9	1.3	1.3	1.3	1.2	1.3	1.5	1.4	1.7	1.7	1.6	0.5	1.5	1.3	0.9	0.8	0.2	1.3	1.1
Ever used hormone-replacement therapy (HRT)	1.1	1.4	4.4	-1.6	-1.2	-0.7	-0.3	-0.7	-1.1	-1.5	-1.0	-0.8	-1.1	-1.2	-1.1	-0.9	-1.4	-1.8	-1.1	-1.5	-1.2	-1.2	-0.7	-1.2	-1.6	-0.3	-2.1	0.9
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	5.2	-0.8	-0.7	-1.1	-0.0	-1.8	-1.3	-1.8	-0.9	-1.1	-1.2	-0.8	-0.8	-1.4	-0.7	-1.3	-1.2	-0.9	-2.3	-1.2	-0.7	-1.5	-0.5	-0.6	-1.0	-1.0
Hearing difficulty/problems with background noise	1.1	1.8	5.4	1.6	1.0	0.6	2.3	-0.3	0.7	-0.0	1.8	1.3	0.6	1.9	1.8	-0.3	1.7	1.5	0.8	1.0	-1.6	1.1	0.8	-1.4	2.2	1.7	2.0	0.1
Hair/balding pattern: Pattern 3	1.1	1.7	5.4	-1.2	-0.7	-1.6	-0.6	-1.9	-1.9	-1.6	-0.6	-1.1	-1.4	-0.5	-0.5	-1.9	-1.1	-1.0	-1.0	-1.0	-1.6	-1.5	-0.8	-1.8	-0.7	-1.3	-0.6	-2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	4.8	1.2	1.2	1.5	0.7	1.2	1.9	1.8	0.6	0.5	1.4	0.5	0.6	1.6	1.1	0.8	0.8	1.2	1.3	0.8	0.9	2.2	0.9	0.9	1.6	1.3
Miserableness	1.1	2.0	4.9	1.1	2.0	1.4	1.4	1.8	1.1	0.5	2.0	1.8	1.2	1.8	1.9	1.1	1.3	1.7	2.0	1.7	0.8	2.2	0.2	0.8	0.4	0.6	1.6	0.8
Eye problems/disorders: Glaucoma	1.1	1.2	3.6	-1.1	-1.7	-0.7	0.5	-0.7	-1.0	-1.1	-1.4	-0.1	-0.8	-1.2	-1.3	-0.6	-1.2	-0.9	-0.7	-0.9	-0.0	-1.6	-1.9	-0.9	-0.8	-1.8	-0.9	-1.7
Arm predicted mass (left)	1.1	5.5	10.0	-2.6	-2.7	-2.6	-0.6	-1.7	-2.1	-2.9	-2.4	-2.8	-3.2	-2.5	-2.6	-2.9	-2.6	-2.4	-2.3	-1.9	-2.3	-2.4	-2.2	-2.8	-2.2	-2.3	-1.1	-1.9
Bipolar Disorder (2018)	1.0	1.6	5.7	0.8	1.5	1.4	-0.4	1.7	0.6	1.0	1.8	2.2	1.2	1.6	1.7	1.4	1.2	0.6	2.4	1.6	0.8	1.4	0.1	1.1	0.1	0.6	-0.0	0.7
Major Depression (MDD)	1.0	1.2	3.6	1.0	1.2	1.4	1.9	0.8	1.0	1.0	0.8	1.0	1.3	0.8	0.8	1.4	1.1	1.6	0.7	0.9	0.7	1.5	-1.4	1.6	0.7	0.2	0.0	1.3
Diabetes (mother)	1.0	1.3	4.5	-1.0	-1.8	-1.2	-0.1	-1.6	-0.2	-0.7	-1.2	-1.1	-1.2	-1.2	-1.1	-1.5	-1.0	-1.1	-0.9	-1.2	-1.7	-2.1	0.5	-1.5	-0.7	-0.7	0.6	-0.5
Average weekly fortified wine intake	1.0	1.2	5.2	-1.3	-0.7	-1.1	-2.3	-0.2	-1.7	-1.1	-0.4	0.6	-1.0	-0.7	-0.3	-0.6	-1.1	-1.2	0.2	-1.1	0.1	-0.7	-1.1	-0.8	-1.5	-1.5	-0.4	-1.9
Medication: Levothyroxine sodium	1.0	1.7	5.4	-1.7	-1.0	-1.5	-0.7	-1.3	-1.3	-1.4	-1.0	-0.6	-1.4	-1.1	-1.1	-1.3	-1.5	-1.3	-1.0	-1.3	-1.2	-0.8	-2.3	-1.2	-1.8	-1.9	-0.5	-1.2
Alcohol intake versus 10 years previously	1.0	1.5	4.9	1.2	0.5	1.7	0.6	1.4	1.5	1.7	0.3	0.8	1.7	0.4	0.3	2.1	1.0	1.1	0.8	1.5	2.1	0.6	0.7	2.2	0.9	1.1	0.1	1.3
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	3.5	1.0	1.3	0.9	1.8	1.1	-0.3	0.1	1.9	1.1	0.9	1.7	1.8	0.2	1.3	0.6	1.4	0.7	-0.6	1.2	0.9	-0.2	0.9	1.9	-0.5	1.7
Headache pain in last month	1.0	1.7	4.2	-1.6	-0.9	-1.6	-1.9	-0.6	-1.6	-1.8	-0.6	-0.7	-1.4	-0.8	-0.6	-1.6	-1.5	-1.5	-1.1	-1.3	-1.2	-0.4	-1.7	-1.4	-1.9	-0.9	-2.0	0.1
Arm fat-free mass (right)	1.0	5.1	9.2	-2.6	-2.6	-2.5	-0.7	-1.8	-2.1	-2.8	-2.3	-2.8	-3.0	-2.4	-2.5	-2.8	-2.5	-2.3	-2.3	-2.1	-2.2	-2.2	-1.9	-2.6	-2.2	-2.2	-1.3	-1.5
Medication for pain relief, constipation, heartburn	1.0	1.7	4.8	1.7	1.5	1.5	1.5	1.1	1.8	1.4	1.1	0.4	1.5	1.3	1.2	1.2	1.6	1.3	1.0	0.8	0.9	0.3	2.2	1.3	1.7	1.4	1.0	1.2
Heart disease (mother)	1.0	1.3	5.9	-0.7	-0.8	-1.0	0.9	-0.9	-1.2	-1.9	-0.1	-1.1	-1.2	-0.1	-0.0	-1.6	-0.7	-1.3	-0.8	-1.5	-2.4	-1.3	0.6	-2.3	-0.4	0.5	-0.2	-0.0
Whole body fat-free mass	1.0	5.7	10.2	-2.7	-2.8	-2.7	-0.9	-1.7	-2.3	-2.7	-2.6	-2.8	-3.2	-2.7	-2.7	-2.8	-2.7	-2.6	-2.4	-2.2	-2.2	-2.4	-2.3	-2.7	-2.2	-2.3	-1.1	-1.9
Qualifications: nursing, teaching	1.0	1.5	7.3	-1.5	-1.0	-1.3	-0.4	-1.0	-0.5	-0.5	-1.5	-2.7	-1.1	-1.6	-1.6	-0.7	-1.3	-1.3	-1.2	-1.6	-0.1	-1.4	-1.4	-0.0	-1.3	-1.0	-1.3	0.1
Whole body water mass	1.0	5.6	10.0	-2.7	-2.8	-2.7	-0.8	-1.6	-2.2	-2.7	-2.6	-2.9	-3.2	-2.7	-2.8	-2.8	-2.7	-2.6	-2.4	-2.1	-2.2	-2.4	-2.1	-2.6	-2.2	-2.2	-1.2	-1.9
Supplements: Fish oil (including cod liver oil)	1.0	1.3	4.7	-0.9	-1.2	-0.6	-1.3	-1.1	-1.5	-0.6	-1.2	-0.4	-0.8	-0.8	-1.1	-1.0	-0.9	-1.6	-0.9	-1.5	-0.7	-1.4	-1.3	-0.8	-0.3	-1.7	-2.2	-1.3
Pack years of smoking	1.0	1.5	4.0	1.3	1.3	1.0	1.8	0.8	0.1	-1.1	1.7	1.4	0.4	1.7	1.6	-0.2	1.3	1.1	1.2	1.9	-0.3	1.6	0.9	-1.1	1.3	1.2	2.0	-0.3
Coronary Artery Disease (CAD)	0.9	1.1	2.7	-1.2	-1.1	-1.4	0.4	-1.0	-0.5	-1.4	-0.9	-1.6	-1.3	-1.0	-1.0	-1.5	-1.1	-0.7	-1.1	-0.9	-1.3	-1.2	-1.0	-1.5	-0.8	-0.1	-0.4	0.1
Fasting Glucose	0.9	1.1	3.7	-1.1	-1.0	-0.7	-0.2	-1.5	-1.0	-1.7	-0.5	0.3	-1.3	-0.5	-0.5	-1.0	-0.8	-1.0	-0.1	-0.9	-1.9	-0.8	-0.9	-1.8	-1.2	-1.1	0.4	-1.6
HDL Cholesterol	0.9	1.5	5.8	-0.4	-1.2	-0.4	0.6	-1.9	-1.1	-2.1	-0.4	-0.3	-1.1	-0.3	-0.3	-1.8	-0.4	-0.6	-0.6	-0.5	-2.2	-1.0	-0.7	-2.4	0.5	-1.3	0.7	-2.4
Lung FVC	0.9	4.4	9.3	-2.3	-1.9	-2.5	-3.0	-2.4	-2.3	-2.3	-1.4	-2.1	-2.6	-1.4	-1.4	-2.7	-2.1	-1.9	-1.9	-1.9	-2.5	-1.7	-1.2	-2.6	-2.1	-1.8	-1.6	-2.4
Chronic bronchitis/emphysema (father)	0.9	1.0	6.6	0.9	0.3	0.8	1.6	1.1	1.2	0.7	0.5	1.4	0.8	0.6	0.6	1.0	0.8	1.0	0.6	0.9	0.9	0.9	0.3	0.4	0.9	1.0	2.6	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	4.2	-1.6	-1.4	-1.4	-0.0	-1.2	-1.4	-1.9	-1.6	-1.7	-1.7	-1.6	-1.7	-1.7	-1.6	-2.0	-1.9	-1.6	-1.2	-1.3	-1.4	-1.4	-1.1	-1.1	-1.4	-0.4
Mouth/teeth dental problems	0.9	1.4	6.7	-0.7	-1.5	-1.0	-0.2	-1.6	0.1	-0.4	-1.9	-2.6	-0.7	-1.7	-1.9	-0.1	-1.1	-0.9	-2.0	-1.4	0.1	-1.5	1.0	0.4	-0.4	-0.1	0.4	-0.1
Medication: Simvastatin	0.9	1.3	6.2	0.4	-0.7	-0.5	0.8	-1.1	-1.2	-2.0	0.6	1.0	-0.7	0.7	0.6	-1.5	0.3	0.1	-0.2	0.4	-2.5	-0.2	1.3	-2.5	1.0	-0.2	0.9	-2.1
Prospective memory result	0.9	1.1	5.3	-0.6	-1.3	-0.8	-0.1	-1.1	0.2	-0.4	-1.5	-1.1	-1.2	-1.4	-1.5	-1.1	-1.0	-0.7	-2.3	-1.1	-1.2	-1.3	0.2	-1.2	0.0	0.1	-0.0	0.3
Breastfed as a baby	0.9	1.1	2.8	-1.0	-1.7	-0.7	0.2	-1.1	-0.7	-0.9	-1.0	-1.5	-1.1	-1.0	-1.0	-1.0	-1.0	-1.0	-1.3	-1.4	-1.2	-1.5	-0.6	-1.1	-0.7	-0.7	-1.4	0.0
Pulse wave reflection index	0.9	1.1	3.5	1.5	0.4	0.6	1.2	1.0	1.1	0.5	0.6	0.8	0.8	0.8	0.5	0.4	1.3	1.8	0.6	1.7	1.5	0.4	0.8	0.7	1.8	0.7	1.9	-0.2
Medication: Paracetamol	0.9	1.5	5.2	-1.5	-1.3	-1.4	-0.8	-1.1	-1.9	-1.7	-1.0	-0.9	-1.3	-0.9	-1.1	-1.5	-1.3	-1.1	-1.2	-1.1	-1.2	-0.4	-2.3	-1.3	-1.2	-0.6	-0.6	-0.5
Qualifications: College or University degree	0.9	2.8	9.1	-2.1	-1.6	-2.2	-0.8	-1.2	-0.4	-0.5	-2.4	-3.0	-1.5	-2.4	-2.4	-0.7	-2.1	-2.0	-1.7	-2.3	0.4	-2.2	-0.3	-0.0	-1.8	-1.4	-1.2	-0.0
Age at last live birth	0.9	1.3	3.1	-1.2	-1.2	-1.5	-1.0	-0.6	-1.7	-0.9	-1.3	-1.3	-1.2	-1.2	-1.3	-1.1	-1.1	-1.3	-0.8	-1.0	0.5	-1.7	-1.5	-0.8	-0.9	-0.9	0.4	-0.8
Average weekly champagne plus white wine intake	0.9	1.3	4.3	-0.6	-1.3	-1.3	0.3	-1.2	0.6	-0.2	-1.7	-1.8	-1.1	-1.6	-1.6	-1.3	-1.1	-0.4	-2.1	-1.4	-0.8	-1.8	0.7	-0.8	-0.0	-0.6	-0.2	0.3
Medication: Paracetamol	0.9	1.3	5.7	-1.1	-1.1	-1.3	-0.5	-1.2	-1.8	-1.7	-1.0	-1.1	-1.2	-0.9	-1.1	-1.5	-1.0	-1.0	-1.5	-1.2	-1.3	-0.4	-2.4	-1.1	-0.5	-0.1	0.1	-0.5
Supplements: Calcium	0.9	1.0	6.8	-0.8	-0.4	-0.8	-1.4	-0.9	-0.3	0.2	-0.8	-1.4	-0.2	-0.8	-0.8	-0.0	-0.7	-1.2	-1.0	-1.5	-0.7	-1.1	0.9	0.4	-0.8	-1.0	-2.6	0.7
Reaction Time	0.8	1.6	3.8	1.8	1.1	1.3	0.1	0.4	1.4	1.9	1.4	0.5	1.6	1.4	1.4	1.3	1.6	1.7	0.7	1.7	0.7	1.4	0.6	1.3	1.6	1.5	-0.4	1.2
Neuroticism	0.8	1.9	3.5	1.3	1.5	1.7	1.1	1.7	1.8	1.6	1.2	1.4	1.3	1.1	1.2	1.3	1.2	1.9	1.3	1.7	1.1	1.6	0.7	1.5	0.8	1.4	1.5	1.7
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.8	3.0	-1.6	-1.6	-1.1	-0.1	-0.7	-1.0	-1.7	-1.6	-1.2	-1.6	-1.6	-1.6	-1.6	-1.5	-1.7	-1.7	-1.7	-1.0	-1.5	-1.2	-1.4	-1.0	-1.2	-0.9	-0.5
Had menopause	0.8	1.0	3.1	-0.6	-0.9	-0.4	1.1	-1.4	-0.4	-1.3	-1.0	-1.2	-0.7	-1.0	-0.9	-0.9	-0.8	-0.8	-1.3	-1.1	-1.7	-1.6	0.3	-1.3	-0.1	-0.0	-1.8	0.4
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	4.8	-1.0	-0.8	-1.2	-0.7	-2.2	-0.5	-0.3	-1.1	-1.3	-1.1	-1.0	-0.9	-1.1	-1.1	-1.2	-0.9	-1.1	-1.3	-0.3	-0.6	-0.5	-0.8	-1.3	-0.2	-1.4
Neuroticism score	0.8	1.7	3.4	1.3	1.5	1.4	1.4	1.5	1.3	1.0	1.5	1.4	1.2	1.3	1.4	1.0	1.2	1.6	1.2	1.5	0.3	1.8	0.4	0.8	0.7	1.5	1.7	1.8
Qualifications: A levels/AS levels or equivalent	0.8	1.7	5.9	-1.4	-1.0	-1.3	-0.3	-1.8	-0.7	-0.1	-1.7	-2.4	-0.8	-1.6	-1.7	-0.0	-1.3	-1.0	-0.8	-1.3	0.3	-1.4	-1.3	0.6	-1.2	-2.3	-1.1	-1.9
Mouth/teeth dental problems: Dentures	0.8	1.3	8.4	0.6	1.2	1.0	-0.2	1.8	0.3	0.3	1.7	2.9	0.8	1.5	1.8	0.3	1.1	1.0	1.7	1.3	0.3	1.1	-1.4	-0.1	0.1	-0.2	0.0	-0.1
Depression (self-reported)	0.8	0.9	3.2	0.7	0.8	1.4	0.2	0.5	1.1	1.8	0.2	0.5	1.0	-0.0	0.2	1.7	0.4	1.1	1.2	1.0	1.8	1.1	0.1	1.8	0.4	0.3	0.7	-0.2
Impedance of arm (left)	0.8	3.6	7.3	2.5	2.4	1.9	0.2	1.3	1.0	2.0	2.0	2.1	2.7	2.2	2.2	2.4	2.4	1.3	2.3	1.6	1.8	1.5	1.2	2.4	2.3	1.7	1.6	0.8
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	5.7	-1.1	-0.5	-0.8	-0.8	-1.1	0.3	0.5	-1.7	-1.7	-0.4	-1.6	-1.6	0.2	-1.1	-1.4	-1.1	-1.2	0.2	-1.0	-1.4	0.9	-1.4	-1.0	-2.4	0.3
Wheeze or whistling in the chest in last year	0.8	1.4	3.3	-1.0	-1.7	-1.6	0.7	-1.2	-0.8	-1.7	-1.5	-0.7	-1.6	-1.3	-1.5	-1.3	-1.3	-1.1	-1.8	-1.0	-1.5	-0.5	-1.0	-1.7	-0.3	-0.4	-0.3	-0.8
Medication: Ibuprofen	0.8	1.0	2.6	-1.3	-0.9	-1.1	-0.5	-0.2	-1.4	-1.0	-1.1	-0.7	-1.0	-1.1	-1.2	-0.5	-1.2	-1.2	-1.1	-1.2	-0.3	-0.6	-1.5	-0.4	-1.2	-0.5	-1.6	0.2
Pulse rate, automated reading	0.8	2.5	11.8	-1.5	-1.0	-1.9	-3.4	-0.8	-1.7	-0.6	-1.6	-1.1	-1.8	-1.6	-1.5	-1.8	-1.7	-2.1	-2.0	-1.6	-1.0	-1.5	-1.3	-0.5	-1.6	-1.8	-1.0	-1.7
Medication for cholesterol	0.8	1.2	6.5	0.7	0.7	0.7	-0.5	1.1	1.3	2.4	-0.0	0.5	1.3	0.1	-0.0	1.9	0.5	0.4	0.6	0.1	2.5	1.1	-0.9	2.4	0.2	-0.4	-0.2	0.6
Commuting to job workplace: Public transport	0.8	1.0	4.8	-0.9	-0.2	-0.4	-2.2	-0.5	-1.5	-0.1	-0.9	-0.6	-0.5	-0.9	-0.7	-0.2	-0.8	-1.9	-0.9	-1.2	-0.0	-1.7	-0.5	0.1	-0.9	-0.9	-1.6	-0.8
Basal metabolic rate	0.8	4.6	8.1	-2.4	-2.6	-2.4	-0.5	-1.3	-2.2	-2.6	-2.3	-2.5	-2.8	-2.4	-2.4	-2.4	-2.4	-2.4	-2.0	-1.8	-2.0	-2.2	-2.2	-2.4	-2.0	-2.1	-0.8	-1.9
Basal cell carcinoma (self-reported)	0.8	1.0	2.5	-1.1	-1.2	-0.8	-0.2	-0.6	-1.4	-1.4	-1.2	-0.2	-0.8	-1.2	-1.2	-0.3	-1.2	-1.1	-1.0	-1.2	-0.1	-1.3	-1.6	-0.8	-1.1	-1.1	-0.9	-0.6
Heart attack/myocardial infarction (self-reported)	0.8	1.1	4.9	-0.9	-1.2	-0.9	-0.3	-1.5	-0.6	-0.9	-0.7	-0.1	-1.3	-0.6	-0.7	-1.6	-0.9	-0.7	-0.2	-0.6	-1.1	-0.9	-0.5	-2.0	-0.5	-1.6	0.1	-2.2
Alcohol drinker status: Previous	0.8	0.9	3.5	0.8	0.6	1.1	0.5	1.9	1.2	1.4	0.5	1.0	1.1	0.6	0.5	1.1	0.8	1.2	0.7	0.6	1.3	0.6	0.0	1.5	0.6	0.8	-0.3	1.4
Worry (Nagel 2018)	0.7	1.4	3.1	1.2	1.5	1.4	0.1	1.0	1.7	1.6	1.3	1.1	1.1	1.1	1.2	1.0	1.1	1.4	1.0	1.2	0.6	1.6	0.7	1.1	0.8	1.8	1.0	1.6
Neuroticism (2016)	0.7	1.1	2.9	0.5	1.3	1.0	0.0	1.1	0.9	1.7	1.2	0.8	1.2	1.1	1.2	1.3	0.7	0.7	1.3	1.1	1.0	1.3	-1.4	1.2	-0.4	-0.8	-0.6	0.7
Lung FEV1/FVC ratio	0.7	3.6	8.2	-2.2	-2.1	-1.5	-2.0	-1.7	-2.2	-1.2	-1.8	-1.4	-1.8	-2.0	-1.8	-1.0	-2.2	-2.9	-0.9	-2.1	-1.5	-1.8	-2.7	-1.3	-2.5	-2.6	-1.7	-2.0
Average weekly spirits intake	0.7	0.8	4.2	0.9	0.5	0.1	1.1	-0.3	0.4	-1.0	0.9	0.4	0.1	1.0	0.9	-0.4	0.9	0.4	0.5	1.3	-1.0	0.2	2.0	-1.0	1.1	1.3	1.8	-0.2
Hair/balding pattern: Pattern 2	0.7	0.9	5.2	0.9	0.4	1.2	-0.2	0.1	2.0	2.3	-0.5	-0.1	1.2	-0.1	-0.4	1.5	0.7	0.7	-0.4	0.2	0.9	0.1	0.3	2.1	0.9	0.0	-0.6	0.4
Heart attack	0.7	0.9	4.1	-0.9	-1.2	-0.8	-0.3	-1.4	-0.4	-0.9	-0.6	0.1	-1.2	-0.7	-0.7	-1.4	-0.9	-0.7	-0.2	-0.6	-0.9	-0.9	-0.2	-2.0	-0.6	-1.4	0.1	-2.0
Medication: Ramipril	0.7	0.9	3.9	0.7	0.7	0.8	0.7	1.2	0.3	-0.4	1.2	0.8	0.2	1.0	1.1	0.4	0.5	1.3	0.8	1.2	0.7	0.8	2.0	-0.5	0.7	1.4	1.9	0.4
Impedance of arm (right)	0.7	3.4	7.1	2.5	2.2	1.9	0.4	1.4	1.2	1.9	2.0	2.0	2.7	2.2	2.2	2.3	2.4	1.2	2.1	1.6	1.5	1.2	1.7	2.2	2.3	1.8	1.3	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.2	-1.2	-0.6	-1.1	-0.8	-0.4	-1.8	-1.0	-0.6	-0.2	-1.0	-0.8	-0.7	-0.6	-1.1	-1.0	-0.6	-0.9	-0.5	-0.3	-1.6	-0.7	-1.4	-0.8	-1.6	-0.3
Exposure to tobacco smoke at home	0.7	0.8	5.1	0.7	0.1	0.5	2.1	0.7	-0.3	-1.3	0.7	0.4	0.5	0.6	0.7	0.1	0.7	0.5	0.3	0.5	-0.7	0.4	0.2	-0.7	0.8	1.6	-0.4	2.3
Medication: Amlodipine	0.7	1.0	3.4	-0.6	-1.7	-0.6	-0.5	-1.1	-1.4	-0.8	-0.7	-0.4	-0.8	-0.5	-0.6	-0.8	-0.6	-1.2	-0.6	-0.7	-1.5	-1.9	1.0	-1.3	-0.0	-0.4	-1.2	-1.4
Mouth/teeth dental problems: Loose teeth	0.7	0.8	8.8	-0.7	-0.2	-1.1	-0.2	-1.0	-0.2	-0.4	-0.7	-0.7	-0.9	-0.8	-0.6	-0.8	-0.7	-0.5	-0.9	0.0	-0.6	-0.6	-3.0	-0.6	-0.5	-1.3	-0.8	-0.9
Medication: Blood pressure	0.7	1.3	3.3	1.2	0.6	1.1	0.7	1.6	-0.3	0.4	1.7	1.6	0.7	1.6	1.6	0.3	1.1	1.4	1.3	1.2	0.5	1.0	1.6	-0.2	1.1	1.1	1.8	0.2
Medication: Lisinopril	0.7	1.0	2.6	-1.2	-1.1	-1.0	-0.5	-1.0	-1.5	-0.9	-1.0	-1.2	-0.9	-1.1	-1.0	-0.4	-1.1	-1.1	-0.8	-1.0	-0.4	-1.6	-0.6	-0.9	-1.0	-0.3	-0.8	-1.4
Alcohol drinker status: Never	0.7	0.9	3.5	0.3	0.6	-0.6	1.2	-0.5	-0.8	-1.1	0.8	-0.6	-0.7	0.6	0.7	-1.6	0.3	0.5	-0.3	0.4	-1.6	-0.2	1.3	-1.6	0.7	1.2	1.9	-0.6
Depression (Nagel 2018)	0.6	0.9	2.1	1.1	1.2	1.2	0.2	0.4	1.5	0.9	1.1	1.1	1.1	1.0	1.2	1.0	1.2	1.5	0.9	1.5	0.3	0.9	-0.0	0.8	1.0	0.3	1.0	0.1
Height	0.6	11.8	21.3	-2.9	-4.0	-3.7	-3.2	-4.1	-4.0	-3.4	-3.8	-4.3	-3.9	-3.3	-3.6	-4.3	-3.1	-3.5	-3.8	-3.5	-3.4	-4.6	-1.9	-3.5	-1.1	-2.4	-0.2	-4.3
Allergy or Eczema	0.6	1.6	3.2	-1.4	-1.6	-1.4	-0.5	-0.8	-1.2	-1.4	-1.7	-1.6	-1.6	-1.6	-1.8	-1.6	-1.5	-1.4	-1.5	-1.3	-0.4	-1.1	-0.6	-0.9	-1.2	-1.0	-0.6	-0.3
Medication: Co-codamol	0.6	0.6	2.3	-0.4	-1.4	-0.6	-0.1	-0.3	-1.2	-1.3	-0.7	0.7	-0.7	-0.7	-0.5	-0.7	-0.5	-0.4	-0.4	-0.4	-0.9	-0.7	-1.5	-1.3	-0.3	-0.8	-0.6	-1.3
Pack years adult smoking proportion	0.6	0.9	3.2	0.8	1.1	0.6	1.4	0.4	-0.2	-1.3	1.4	0.8	0.1	1.3	1.2	-0.4	0.9	0.7	0.8	1.5	-0.6	1.1	0.6	-1.2	0.8	0.8	1.8	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.8	1.0	1.2	1.1	0.6	-0.4	1.2	0.9	0.8	0.6	0.8	0.7	0.9	0.9	0.9	1.3	0.6	1.3	-0.2	1.0	-0.8	0.4	0.9	-0.3	1.2	-0.6
Qualifications: CSEs or equivalent	0.6	0.8	3.9	1.2	0.7	1.1	0.9	0.0	0.6	-0.0	1.0	0.1	0.6	1.1	1.1	0.2	1.1	1.4	0.7	1.4	-0.6	0.6	0.5	-0.0	1.3	1.4	2.0	0.2
Sitting height	0.6	4.4	9.1	-1.7	-2.1	-2.2	-2.1	-2.2	-2.5	-1.7	-2.1	-2.2	-2.5	-2.0	-2.1	-2.9	-1.9	-2.3	-2.2	-1.8	-2.2	-2.5	-2.1	-2.2	-1.0	-2.1	-1.0	-3.0
Alcohol usually taken with meals	0.6	1.0	2.3	-1.1	-1.2	-1.5	-0.5	-0.9	-1.5	-1.1	-1.0	-1.1	-1.3	-1.0	-1.0	-1.2	-1.2	-0.9	-0.6	-1.0	-1.2	-0.7	0.3	-1.0	-0.9	-0.9	-1.3	-0.3
Comparative body size at age 10	0.6	1.8	8.6	0.5	0.7	1.5	1.8	2.3	0.9	0.6	0.5	0.9	1.4	0.3	0.3	2.5	0.6	0.9	1.3	1.3	2.9	0.4	-0.0	1.6	-0.1	1.2	0.4	2.6
Pulse wave peak to peak time	0.6	0.7	3.8	-1.0	-0.5	-0.1	-0.4	-0.6	-0.5	0.1	-0.9	-1.1	-0.2	-0.9	-0.9	0.3	-0.8	-1.5	-0.5	-1.3	-0.1	-0.7	-1.3	0.2	-0.9	-0.5	-1.9	1.1
Mean time to correctly identify matches	0.6	1.2	3.4	1.5	0.8	1.2	0.2	-0.4	1.4	1.2	1.2	0.6	1.1	1.3	1.3	0.5	1.5	1.5	0.3	1.2	-0.4	0.9	1.8	0.3	1.7	1.4	-0.2	0.5
Leg fat-free mass (right)	0.6	3.2	6.3	-1.9	-2.3	-2.0	0.0	-0.8	-2.0	-2.5	-1.9	-2.0	-2.4	-2.0	-2.1	-1.9	-1.9	-2.2	-1.5	-1.5	-1.6	-1.9	-1.8	-2.1	-1.4	-1.5	-0.0	-1.6
Asthma (self-reported)	0.6	1.2	5.5	0.4	0.7	1.1	1.0	1.4	2.1	1.7	-0.0	0.4	1.3	0.2	-0.0	1.8	0.5	0.5	0.4	0.1	2.1	0.5	-0.7	2.3	-0.2	-0.5	0.2	1.6
Medication: Gliclazide	0.6	0.7	1.8	-1.0	-0.9	-0.9	0.1	-1.0	0.1	-0.9	-1.0	-1.2	-1.1	-0.9	-1.1	-1.3	-1.0	-0.6	-1.1	-0.9	-0.6	-1.0	-0.4	-1.0	-0.5	-0.3	0.9	-0.4
Leg predicted mass (right)	0.6	3.1	6.2	-1.9	-2.2	-2.0	0.0	-0.7	-2.0	-2.5	-1.9	-2.0	-2.4	-2.0	-2.0	-1.9	-1.9	-2.2	-1.5	-1.5	-1.5	-1.9	-1.8	-2.1	-1.4	-1.5	-0.1	-1.5
Schizophrenia vs Biploar Disorder	0.5	0.7	3.2	0.1	-0.5	-0.4	0.4	-1.8	-0.7	-0.5	-0.4	-1.8	-0.5	-0.3	-0.5	-0.7	-0.1	-0.1	-1.2	-0.4	-1.2	-0.5	-0.1	-0.5	0.5	-1.2	1.1	-1.4
Ulcerative Colitis (UC)	0.5	1.0	2.9	-0.9	-1.0	-1.2	-1.3	-0.9	-1.3	-1.2	-0.4	-0.5	-1.3	-0.6	-0.6	-1.7	-0.8	-1.1	-0.8	-0.9	-1.7	-0.7	0.1	-1.5	-0.6	0.1	-0.4	-0.8
Breast Cancer	0.5	1.3	4.5	1.0	0.4	1.2	0.8	0.8	1.1	2.0	0.1	1.1	1.1	0.2	0.2	2.1	0.7	0.6	1.3	1.5	2.0	0.5	-0.7	1.6	0.8	-0.2	1.8	-0.9
Age at First Birth	0.5	0.7	4.7	-0.7	-0.7	-0.8	-0.7	-1.3	-0.6	-1.5	-0.6	-0.8	-0.9	-0.4	-0.6	-1.2	-0.5	-0.8	-0.3	-0.4	-0.2	-0.8	0.5	-0.9	-0.2	-1.2	0.6	-2.2
LDL Cholesterol	0.5	0.8	1.8	0.9	1.3	0.6	0.1	1.2	0.5	0.9	1.1	1.1	0.9	1.1	1.3	1.0	0.9	0.7	1.3	1.3	0.6	1.3	0.3	0.9	0.3	0.8	-0.1	0.8
Smoking Status	0.5	1.2	4.4	-1.2	-1.0	-0.2	-2.1	1.0	-0.1	0.3	-1.2	0.9	-0.4	-1.4	-1.3	0.1	-1.1	-1.3	-0.7	-0.8	1.3	-0.9	-0.9	0.7	-1.7	-0.9	-2.1	0.6
Sensitivity / hurt feelings	0.5	0.9	2.5	-1.1	-0.7	-0.9	-1.0	-0.8	-0.9	-0.4	-0.7	-0.5	-1.4	-0.8	-0.7	-1.5	-1.1	-0.6	-0.8	-0.7	-1.5	0.2	-1.6	-1.3	-1.2	-0.7	0.0	-0.7
Severe depression (siblings)	0.5	0.5	1.9	-0.8	-1.1	-0.6	-0.1	-0.9	-0.2	-0.7	-0.9	-0.2	-0.5	-0.9	-0.9	-0.3	-0.8	-1.4	-0.7	-1.1	-0.4	-1.3	0.1	-0.7	-0.7	0.0	0.6	-0.7
Leg fat-free mass (left)	0.5	2.8	5.4	-1.8	-2.1	-1.9	0.1	-0.7	-1.8	-2.3	-1.8	-2.0	-2.2	-1.9	-1.9	-1.8	-1.8	-2.1	-1.5	-1.4	-1.6	-1.7	-1.6	-1.9	-1.4	-1.4	-0.1	-1.3
Serious illness, injury or assault to yourself	0.5	0.6	4.0	-0.8	-0.8	-0.7	-0.9	-0.2	-0.8	-1.2	-0.7	-0.3	-0.7	-0.7	-0.7	-0.4	-0.7	-0.8	-0.4	-0.5	0.1	-1.0	-0.8	-0.6	-0.8	-1.1	0.0	-2.0
Stomach or abdominal pain in last month	0.5	0.6	3.8	-0.6	-1.1	-0.2	-1.9	-0.0	0.6	0.6	-0.9	0.4	-0.2	-0.8	-1.0	0.6	-0.6	-1.1	-0.1	-0.6	0.6	-0.4	-1.1	0.9	-0.7	-1.2	0.3	-0.1
Leg predicted mass (left)	0.5	2.5	5.0	-1.7	-2.0	-1.8	0.1	-0.6	-1.6	-2.2	-1.7	-1.9	-2.1	-1.8	-1.9	-1.6	-1.7	-2.0	-1.4	-1.4	-1.5	-1.6	-1.6	-1.8	-1.3	-1.3	-0.1	-1.1
Allergy	0.5	1.0	3.9	0.9	0.7	0.5	0.8	-0.4	-0.3	-0.7	1.5	0.0	0.3	1.4	1.5	-0.6	1.0	0.9	0.7	0.8	-1.8	0.4	2.0	-1.1	1.4	1.9	-0.2	0.3
Pain all over the body in last month	0.5	0.5	3.1	-0.9	-0.7	-0.5	-0.5	-0.3	-0.5	-1.0	-0.8	-0.1	-0.7	-0.8	-0.9	-0.0	-0.8	-0.6	-0.5	-0.5	0.0	-0.7	-1.7	-0.3	-1.2	-1.0	-0.2	0.0
Fluid intelligence score	0.5	1.0	2.2	-1.4	-1.0	-1.5	-1.3	-0.8	-1.4	-0.9	-0.9	-1.4	-1.1	-1.0	-1.0	-1.0	-1.1	-0.9	-0.2	-0.8	-0.1	-1.5	-0.8	-0.4	-1.2	-0.5	0.4	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	3.2	-0.3	-0.6	-0.7	0.4	-1.0	-0.7	-1.7	0.2	0.2	-1.0	-0.1	0.1	-1.1	-0.4	0.5	0.4	0.6	-1.4	0.0	-1.3	-1.8	-0.2	-0.6	1.3	-1.6
Noisy workplace	0.5	0.6	3.7	0.8	0.6	0.2	1.2	0.1	1.9	0.9	0.5	0.0	0.6	0.8	0.5	0.0	0.9	0.9	-0.3	0.6	-0.0	0.7	1.7	-0.1	1.1	1.1	0.7	0.3
Asthma	0.5	0.9	4.8	0.2	0.6	0.9	0.9	1.2	1.8	1.5	-0.2	0.3	1.1	-0.0	-0.2	1.6	0.3	0.3	0.1	-0.1	1.9	0.3	-0.7	2.2	-0.4	-0.6	0.1	1.4
Standing height	0.5	5.0	12.5	-2.0	-2.0	-2.6	-3.1	-2.4	-2.7	-1.9	-2.1	-2.5	-2.6	-2.0	-2.1	-2.8	-2.0	-2.5	-1.8	-1.9	-1.9	-2.6	-1.8	-2.0	-1.3	-2.5	-0.8	-3.5
Gout (self-reported)	0.5	0.7	3.2	1.3	0.5	0.7	0.8	0.3	0.2	0.2	0.8	0.6	0.7	1.0	0.7	0.6	1.1	1.2	0.0	1.1	-0.0	0.8	0.3	0.4	1.8	1.1	1.3	0.4
Number of full brothers	0.5	0.6	1.9	0.9	0.9	1.4	0.0	0.2	0.3	-0.2	1.2	0.9	0.5	1.1	1.3	0.4	1.0	0.6	0.7	1.2	-0.2	1.0	-0.8	-0.2	0.8	0.6	0.5	-0.3
Emphysema/chronic bronchitis	0.5	0.6	1.5	0.7	1.0	1.1	0.7	0.7	1.1	0.8	0.9	0.5	0.9	0.8	0.8	1.2	0.8	0.7	0.7	0.8	0.9	0.9	0.3	0.7	0.2	0.6	0.4	0.7
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.7	0.2	0.3	0.5	1.7	-0.3	1.0	0.2	0.9	-0.1	0.6	0.8	0.7	0.3	0.7	0.5	1.2	0.4	-0.5	0.6	1.6	0.0	0.1	0.8	-0.2	1.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.7	0.9	1.3	0.7	0.5	0.5	0.7	0.6	1.0	0.6	0.7	1.1	1.0	0.3	1.0	0.9	1.0	0.7	0.7	1.1	0.2	0.7	1.0	0.5	0.6	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	4.9	0.6	-0.1	1.0	0.5	0.3	0.7	0.5	0.4	0.6	0.4	0.3	0.5	0.4	0.5	0.5	1.2	1.0	0.1	-0.0	1.0	0.2	0.6	1.1	2.2	0.3
Illnesses of father: Heart disease	0.5	0.7	3.6	-0.6	-0.8	-0.4	-0.7	-0.7	-1.2	-0.6	0.1	0.5	-0.6	-0.1	0.2	-1.0	-0.4	-0.4	-0.1	-0.2	-1.7	-1.1	-1.9	-1.3	-0.4	-1.0	-0.5	-1.4
Wears glasses or contact lenses	0.5	0.6	2.6	-1.1	-0.7	-0.5	-1.6	-0.2	-0.4	-0.2	-0.5	0.0	-0.7	-0.6	-0.5	-0.3	-0.8	-1.1	0.1	-0.8	0.3	-0.9	-0.3	-0.5	-1.4	-1.6	-0.8	-1.0
High cholesterol (Self-reported)	0.5	1.0	5.0	-0.3	-0.6	-0.7	-0.3	-0.9	-1.7	-1.6	0.1	0.5	-0.9	0.1	0.2	-1.5	-0.3	-0.7	-0.6	-0.7	-2.2	-0.6	0.3	-1.9	0.1	-0.8	-0.8	-1.7
Risk taking	0.5	0.8	3.4	0.5	0.5	0.8	0.9	1.6	0.8	0.2	0.5	1.0	0.8	0.5	0.5	0.9	0.5	1.0	1.2	1.0	1.8	1.4	-0.1	0.8	0.2	-0.5	0.7	0.6
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	4.0	0.3	-0.4	0.3	-0.1	0.7	0.8	1.0	0.1	0.8	0.2	-0.1	-0.1	0.7	0.2	1.0	1.3	1.4	1.3	0.4	-0.4	0.6	0.0	0.2	2.0	-0.0
Impedance of whole body	0.5	2.5	5.4	2.1	2.0	1.6	-0.3	0.6	0.9	1.9	1.7	1.8	2.3	1.9	1.9	1.8	2.0	1.3	1.8	1.3	1.3	1.1	1.3	2.0	2.0	1.1	1.0	0.3
Bipolar Disorder or Schizophrenia	0.4	1.0	2.7	0.5	1.3	1.6	-0.6	0.8	1.0	1.7	1.0	1.4	1.1	0.8	1.0	1.5	0.9	0.4	1.6	1.0	0.8	0.7	-0.7	1.4	-0.1	-0.5	0.1	0.5
Alzheimer’s Disease (including proxy)	0.4	0.5	1.7	-0.8	-0.2	-0.6	-0.8	-0.7	-0.9	-1.0	-0.3	-1.3	-0.9	-0.4	-0.4	-0.9	-0.8	-0.4	-0.6	-0.2	-0.4	-0.6	-0.0	-1.0	-0.9	-1.2	-0.6	-0.9
Prostate Cancer	0.4	0.5	5.6	0.4	0.4	0.1	0.4	0.3	-0.8	-0.8	0.8	0.5	-0.3	0.8	0.8	-0.6	0.6	0.5	0.3	0.9	-0.8	0.1	-2.4	-0.8	0.4	0.0	0.4	-1.0
Mean Putamen Volume	0.4	0.5	2.3	-0.8	-0.2	-0.9	-0.7	0.1	-0.8	-1.5	-0.2	0.1	-1.0	-0.5	-0.0	-0.9	-0.7	-0.9	-0.4	-0.4	-0.7	-0.6	-0.5	-1.4	-0.8	0.2	-0.2	0.2
Respiratory disease	0.4	1.0	4.9	0.3	0.3	0.7	1.2	1.1	2.2	1.3	-0.0	0.1	1.1	0.2	-0.1	1.4	0.4	0.4	0.4	0.0	1.5	0.3	0.7	1.9	-0.3	0.2	0.3	2.2
Medication for hormone replacement therapy	0.4	0.4	2.1	-0.7	0.2	-0.2	-0.5	0.4	-0.7	-1.5	0.7	-0.1	-0.7	0.4	0.6	-1.0	-0.3	-0.1	0.2	0.2	-1.2	0.3	0.1	-1.3	-0.7	0.4	-0.0	0.5
Medication: Metformin	0.4	0.6	4.3	-0.2	-0.5	-0.6	0.4	-0.9	-0.1	-1.3	-0.2	0.0	-1.1	-0.1	-0.3	-1.6	-0.3	-0.3	-0.8	-0.3	-1.2	0.0	1.2	-2.1	0.4	0.5	0.3	-0.7
Current tobacco smoking	0.4	0.6	2.2	-0.7	-0.6	-0.4	-0.5	-0.6	-0.3	-0.3	-1.1	-0.0	-0.7	-1.0	-1.0	-0.3	-0.8	-0.7	-0.9	-0.3	-0.2	-1.1	-1.2	-0.4	-0.8	-1.5	-0.6	-1.1
Nervous feelings	0.4	0.8	1.9	-0.9	-1.0	-1.0	-1.4	-1.4	-0.1	-0.3	-0.9	-1.1	-1.2	-0.9	-1.0	-1.1	-0.9	-0.7	-0.8	-0.5	-1.1	-1.2	-0.9	-0.9	-0.6	-0.5	0.5	-0.7
Weight	0.4	2.0	5.4	-1.4	-2.1	-1.5	0.5	-0.6	-1.6	-2.3	-1.5	-1.2	-1.8	-1.6	-1.6	-1.4	-1.4	-1.8	-1.0	-0.9	-1.3	-1.6	-1.7	-1.8	-1.1	-1.3	-0.2	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	3.8	0.5	0.7	0.8	-0.1	0.5	0.7	0.5	0.8	0.3	0.8	0.7	0.7	0.5	0.7	0.2	0.2	0.3	0.3	0.3	1.9	0.5	0.2	0.7	-1.4	0.8
Medication: Cholesterol lowering	0.4	0.6	3.6	0.3	-0.1	-0.2	0.1	-0.1	-0.7	-1.4	1.0	1.0	-0.4	0.9	0.9	-1.0	0.4	0.2	0.3	0.5	-1.3	0.2	0.7	-1.9	0.5	-0.0	0.8	-1.3
Medication: Lansoprazole	0.4	0.5	2.0	-0.1	-1.1	0.3	0.7	0.2	-0.2	-0.7	-0.7	-0.5	-0.4	-0.4	-0.5	-0.4	-0.3	-0.8	-0.6	-0.7	-0.3	-1.3	0.9	-0.8	0.6	1.0	1.4	0.8
Pulse wave Arterial Stiffness index	0.4	0.5	3.1	0.7	0.2	-0.2	-0.1	0.4	0.4	-0.1	0.6	0.7	-0.1	0.6	0.6	-0.5	0.5	1.2	0.2	1.0	-0.1	0.4	1.2	-0.3	0.6	0.2	1.8	-1.3
Length of working week for main job	0.4	0.5	2.6	0.2	1.0	0.0	0.6	-0.7	0.4	-0.3	0.6	-0.4	0.1	0.7	0.7	-0.2	0.4	0.8	-0.4	0.1	-1.3	0.9	-1.6	-0.8	0.3	-0.4	-1.1	-0.3
Hair/balding pattern: Pattern 4	0.4	0.9	3.4	-0.6	-1.0	-1.0	0.1	-0.6	-0.8	-1.5	-0.3	-1.3	-1.2	-0.6	-0.3	-1.5	-0.8	-0.5	-0.9	-0.9	-1.8	-0.7	0.9	-1.8	-0.5	0.8	-0.3	0.5
Glaucoma (self-reported)	0.4	0.5	2.2	-0.5	-1.0	-0.2	0.7	-0.4	-1.1	-0.7	-0.7	0.2	-0.5	-0.6	-0.6	-0.1	-0.7	-0.5	-0.3	-0.5	-0.2	-1.0	-1.5	-0.8	-0.4	-0.7	-0.4	-1.4
Chest pain or discomfort	0.4	0.6	2.3	-0.9	-1.1	-1.2	-0.2	-0.4	-0.1	-1.0	-0.7	-0.1	-1.1	-0.6	-0.9	-1.0	-0.7	-0.9	-0.9	-0.5	-0.6	-0.7	-1.5	-1.3	-0.6	-0.4	0.2	-0.1
Supplements: Vitamin C	0.4	0.5	3.2	-0.3	-0.2	-0.6	0.6	-0.8	-0.6	-0.4	-0.6	-1.2	-0.4	-0.3	-0.5	-0.9	-0.2	-0.8	-1.1	-1.1	-1.0	-0.7	0.3	-0.5	0.2	0.4	-1.8	0.7
Hypertension (Self-reported)	0.4	1.0	4.5	1.1	0.3	1.0	1.8	0.3	0.4	0.3	1.0	0.7	0.5	1.1	1.1	-0.0	1.1	1.0	0.7	0.6	-0.5	0.3	2.1	-0.3	1.5	1.2	2.0	0.3
Ever had bowel cancer screening	0.4	0.4	0.9	-0.8	-0.7	-0.8	0.1	-0.9	0.1	-0.5	-0.7	-0.2	-0.7	-0.7	-0.8	-0.5	-0.6	-1.0	-0.6	-0.6	-0.6	-0.9	0.4	-0.3	-0.6	-0.8	0.0	-0.9
Friendships satisfaction	0.4	0.5	1.9	-0.8	-0.3	-0.6	-1.4	-0.6	-0.9	-0.4	-0.2	-0.7	-0.7	-0.5	-0.3	-0.2	-0.8	-0.8	-0.0	-0.3	-0.2	-0.1	-0.3	0.2	-1.3	-1.2	-0.9	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.4	-0.8	-0.7	-0.1	0.1	0.9	0.1	-0.4	-1.0	-0.3	-0.3	-1.0	-1.0	0.2	-0.8	-0.6	-1.0	-0.4	0.9	0.2	-0.3	0.7	-1.1	-0.2	-0.8	1.2
Osteoarthritis (self-reported)	0.4	0.5	2.3	-1.3	-0.7	-0.6	-1.1	-0.2	-0.6	-1.2	-0.6	-0.7	-0.9	-0.8	-0.7	-0.5	-1.0	-0.7	-0.1	-0.8	0.3	-0.3	-0.6	-0.4	-1.5	-0.4	0.0	-0.4
Number of self-reported non-cancer illnesses	0.4	0.8	2.8	-1.0	-1.0	-0.6	-0.4	-1.2	-0.6	-0.6	-0.6	-0.2	-1.0	-0.6	-0.6	-1.0	-0.9	-1.2	-0.5	-1.2	-1.7	-0.8	-0.1	-1.0	-1.0	-1.1	0.3	-1.1
Medication: Blood pressure	0.4	0.7	2.9	-0.5	-0.8	-0.6	0.8	-1.2	-0.4	-1.7	-0.3	-0.9	-1.0	-0.4	-0.3	-1.2	-0.4	-0.1	-0.5	-0.1	-1.4	-1.2	0.7	-1.7	0.0	0.3	0.5	-0.6
Pain type(s) experienced in last month: Hip pain	0.4	0.6	2.6	-0.2	-0.9	-0.4	0.8	-1.1	-0.8	-1.6	-0.2	-0.2	-0.6	-0.1	-0.2	-0.7	-0.2	0.2	-0.2	0.2	-1.1	-0.5	-0.8	-1.2	0.2	-0.9	0.6	-1.6
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.2	-0.4	-0.2	0.4	-0.7	-0.1	0.8	0.9	-1.0	-0.4	0.2	-0.9	-1.0	0.9	-0.4	-0.5	-0.4	-0.6	0.7	-0.3	-0.8	1.1	-0.4	-0.9	-0.9	0.6
Ovarian Cancer	0.3	0.3	2.3	-0.4	-0.2	-0.2	-0.7	-0.8	-0.7	-0.5	-0.1	-1.5	-0.3	-0.2	-0.0	-0.2	-0.3	-0.7	0.1	-0.0	-0.7	-1.5	-0.7	-0.3	-0.6	-0.0	-0.2	0.4
Body Mass Index (BMI) (2010)	0.3	0.4	2.0	-0.6	-1.4	-0.4	0.6	-0.1	-0.2	-0.8	-0.9	-0.2	-0.7	-0.9	-0.9	-0.1	-0.7	-0.7	-0.1	-0.2	-0.2	-1.1	-0.3	-0.6	-0.3	-0.5	0.0	-0.4
Rheumatoid Arthritis	0.3	0.4	1.3	0.8	0.3	0.8	0.8	0.2	0.6	0.9	0.1	-0.3	0.7	0.2	0.2	0.5	0.5	0.6	0.6	0.3	0.6	0.5	1.1	0.9	0.9	0.5	0.6	1.0
Ulcerative Colitis	0.3	0.5	1.7	-0.7	-0.8	-0.6	-0.9	-0.9	-0.8	-0.8	-0.2	-0.3	-0.9	-0.3	-0.5	-0.8	-0.6	-0.4	-0.4	-0.4	-1.3	-0.4	-1.0	-1.0	-0.8	-0.2	-0.3	-0.2
Blood Platelet Count	0.3	3.3	10.6	-2.6	-1.6	-1.8	-3.2	0.0	-1.2	-0.5	-1.9	-1.1	-1.9	-2.1	-1.8	-1.0	-2.4	-1.8	-1.2	-1.8	0.4	-2.5	-2.1	-0.7	-3.0	-2.2	-1.8	-1.1
Hearing difficulty/problems: Yes	0.3	0.5	3.4	0.5	-0.3	-0.1	1.8	-0.6	0.4	-1.0	0.3	0.1	-0.1	0.6	0.3	-0.7	0.5	0.4	-0.5	-0.1	-0.8	0.0	0.4	-1.2	1.2	1.0	0.9	-0.0
Systolic blood pressure, automated reading	0.3	1.0	4.6	-0.2	-1.0	-0.8	1.1	-1.4	-1.4	-1.4	-0.4	-0.3	-0.9	-0.2	-0.2	-1.2	-0.3	-0.6	-0.6	-1.0	-2.1	-1.3	-0.8	-1.7	0.6	0.1	1.2	-1.2
Maternal smoking around birth	0.3	0.4	3.2	0.3	0.3	0.2	0.1	1.0	-0.5	-0.2	0.6	1.8	0.0	0.5	0.5	-0.4	0.3	-0.2	0.3	0.5	-0.1	1.3	1.2	-0.2	0.2	0.5	0.2	0.1
Relative age voice broke	0.3	0.4	2.0	-0.0	-0.0	0.1	-0.3	-0.4	1.0	1.4	-0.5	-0.9	0.4	-0.4	-0.5	0.8	-0.1	-0.1	-0.5	-0.3	0.8	-0.4	-0.9	1.2	-0.4	-0.2	-0.9	0.6
High blood pressure	0.3	0.7	4.7	0.8	0.2	0.6	1.4	0.1	0.2	0.1	0.9	0.5	0.2	1.0	0.9	-0.3	0.8	0.8	0.6	0.4	-0.6	0.3	2.2	-0.5	1.2	1.0	1.8	0.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	3.0	0.1	-0.5	-0.8	-0.2	-0.2	-0.5	-0.9	-0.6	0.1	-0.6	-0.4	-0.4	-0.6	-0.2	-0.1	-1.0	-0.2	-0.6	-0.3	-1.7	-0.7	0.3	-0.6	-0.3	-1.2
Hip circumference	0.3	1.1	3.8	-1.1	-1.6	-0.9	1.0	-0.2	-1.3	-1.9	-1.0	-0.7	-1.1	-1.2	-1.2	-0.4	-1.1	-1.5	-0.7	-0.8	-0.8	-1.2	-1.3	-1.1	-1.0	-0.8	-0.9	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.8	-0.3	-1.0	-0.3	0.0	-0.2	1.2	0.8	-1.3	-0.4	-0.4	-1.4	-1.3	-0.1	-0.6	-0.4	-1.1	-0.4	0.1	-0.7	0.0	0.3	0.1	0.2	1.2	0.1
Loud music exposure frequency	0.3	0.3	1.3	-0.3	-0.6	-0.3	0.5	-0.7	-0.1	-0.4	-0.9	-1.0	-0.5	-0.7	-1.0	-0.4	-0.4	-0.2	-1.1	-0.6	-0.1	-0.2	-0.4	-0.2	0.3	0.2	-0.3	0.4
Blood clot in the leg (DVT)	0.3	0.4	1.1	-0.4	-0.2	0.3	-0.4	-0.2	0.7	0.7	-1.0	-0.4	0.2	-0.9	-1.0	0.9	-0.4	-0.4	-0.5	-0.6	0.7	-0.4	-0.8	1.1	-0.4	-0.9	-0.8	0.5
Medication: Omeprazole	0.3	0.3	1.5	-0.5	-1.2	-0.3	-0.8	-0.0	0.6	0.5	-0.5	0.4	-0.3	-0.8	-0.7	0.1	-0.5	0.1	0.6	0.5	0.6	-0.3	-0.8	-0.1	-0.7	-0.4	1.2	-0.5
Medication: Seretide 50 evohaler	0.3	0.4	1.6	0.5	0.3	0.6	0.5	0.7	0.9	1.2	0.1	1.2	0.7	0.0	0.2	1.1	0.3	0.5	0.7	-0.1	0.8	0.2	0.6	0.9	0.2	0.2	0.5	0.3
Family relationship satisfaction	0.3	0.4	2.2	0.3	0.4	0.8	-0.5	0.1	0.5	0.8	0.2	-0.3	0.5	-0.1	0.0	0.8	0.2	-0.2	-0.0	0.1	0.4	0.5	1.0	1.2	-0.1	0.8	-1.5	1.1
Medication: Aspirin	0.3	0.4	2.1	-0.3	-0.2	-0.2	-0.5	-0.7	-0.6	-1.0	0.5	0.4	-0.5	0.4	0.4	-0.9	-0.0	-0.1	0.5	0.4	-0.8	0.2	0.3	-1.4	-0.3	-0.8	-0.4	-1.4
Average weekly red wine intake	0.3	0.5	1.5	-0.4	-0.9	-0.3	0.1	-1.2	-0.1	0.1	-1.2	-0.6	-0.4	-1.2	-1.0	-0.2	-0.6	-0.6	-0.9	-1.2	-0.2	-0.6	-0.0	0.2	-0.1	-0.7	-0.4	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	3.0	-0.4	-0.6	-0.6	-0.6	-0.3	-0.3	-0.7	0.3	0.3	-0.7	0.1	0.1	-1.0	-0.3	-0.1	-0.3	0.4	-0.8	-0.6	0.8	-1.7	-0.3	0.8	0.1	-0.4
Osteoporosis (self-reported)	0.3	0.4	2.2	0.3	0.5	0.1	1.0	1.1	1.1	0.4	0.4	0.1	0.3	0.4	0.3	0.1	0.4	0.5	-0.0	0.3	0.2	0.8	1.5	0.2	0.1	0.5	-0.1	1.5
Medication: Aspirin	0.3	0.4	2.2	-0.2	-0.1	-0.3	-0.6	-0.8	-0.3	-0.8	0.6	0.6	-0.3	0.6	0.5	-1.0	0.2	-0.2	0.5	0.2	-1.0	0.2	0.6	-1.3	0.0	-0.5	-0.2	-1.5
Guilty feelings	0.3	0.4	2.7	0.2	0.5	0.1	0.3	1.7	0.2	0.2	0.6	0.8	0.2	0.5	0.5	0.2	0.3	0.4	0.1	0.6	0.3	0.7	-0.3	-0.1	-0.1	1.0	0.6	1.5
Myopia	0.3	0.4	2.1	-0.7	-0.2	-0.3	-1.2	-0.1	-1.5	-0.1	-0.2	0.4	-0.6	-0.4	-0.1	-0.6	-0.6	-0.9	0.1	-0.7	0.0	-0.4	0.2	-0.3	-0.8	-0.6	-0.3	-1.1
Schizophrenia (2018)	0.2	0.3	1.9	0.0	0.4	0.9	-0.5	-0.3	0.8	1.4	-0.1	0.0	0.5	-0.2	-0.1	0.9	0.2	-0.0	0.1	-0.0	0.4	-0.3	-1.2	0.9	-0.2	-1.1	-0.1	0.1
Alzheimer’s Disease (in father)	0.2	0.2	1.2	0.0	0.2	-0.1	-0.5	0.1	-1.1	-0.9	0.5	0.0	-0.3	0.5	0.6	-0.5	0.1	-0.1	0.4	0.2	0.2	-0.1	-0.0	-0.6	-0.3	-0.9	0.3	-1.1
HbA1C	0.2	0.2	1.0	-0.4	-0.3	-0.6	0.3	0.1	-0.4	-0.4	-0.5	-0.6	-0.3	-0.3	-0.3	-0.4	-0.4	-0.6	-0.2	-0.7	-0.2	-1.0	-0.5	-0.5	-0.2	-0.7	-0.3	-0.6
Schizophrenia (2014)	0.2	0.5	3.2	-0.6	-0.2	0.4	-1.1	-0.1	0.2	0.8	-0.5	0.2	-0.0	-0.6	-0.6	0.7	-0.4	-0.4	0.1	-0.4	0.5	-0.5	-1.8	0.6	-0.9	-1.5	0.3	-0.1
Cardiovascular Disease	0.2	0.6	1.8	0.4	0.2	0.3	0.8	0.4	-1.0	-0.9	1.0	1.1	-0.2	1.1	1.0	-0.9	0.5	0.5	0.7	0.3	-1.3	0.7	1.3	-1.1	0.6	0.0	1.2	-0.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	1.1	0.2	0.5	0.1	-0.3	0.2	0.6	0.3	0.8	0.7	-0.1	0.8	0.7	-0.4	0.4	0.3	0.5	0.8	0.2	0.3	1.0	-0.5	0.1	0.2	0.4	-0.7
Impedance of leg (right)	0.2	1.0	2.1	1.2	1.3	0.8	-0.8	-0.3	0.9	1.3	1.1	0.8	1.5	1.2	1.1	0.9	1.3	1.2	0.8	0.8	0.5	0.6	1.4	1.3	1.0	0.8	-0.3	0.5
Trunk fat percentage	0.2	0.7	3.7	0.9	-0.0	0.6	1.9	1.1	-0.2	-0.7	0.7	1.4	0.7	0.7	0.7	0.8	0.9	-0.1	1.3	0.9	0.1	0.2	-0.3	0.0	1.0	0.5	1.5	-0.0
Taking other prescription medications	0.2	0.3	2.4	0.1	-0.2	0.4	1.4	-0.1	0.2	-0.1	0.2	1.6	0.0	0.2	0.3	0.1	-0.0	0.3	0.5	0.1	-0.7	0.4	-0.6	-0.8	0.1	-0.7	0.8	-1.0
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	0.1	-0.1	-0.1	0.8	-0.2	0.3	-0.4	0.0	0.5	-0.2	0.2	0.1	-0.8	0.2	-0.6	-0.2	-0.3	-0.8	-0.6	0.5	-0.9	0.3	0.2	-0.9	-0.2
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.8	-0.6	-0.7	-0.6	-0.2	-0.1	-0.2	-0.0	-1.3	-0.9	-0.6	-1.1	-1.3	-0.1	-0.8	-0.8	-0.8	-0.6	1.0	-0.2	-1.0	0.5	-0.7	-1.2	0.4	-0.2
Impedance of leg (left)	0.2	1.0	2.3	1.3	1.3	1.0	-0.6	0.1	0.7	1.2	1.2	1.1	1.5	1.4	1.3	0.8	1.4	1.2	1.0	0.9	0.8	0.6	1.2	1.3	1.2	0.7	-0.0	0.2
Waist circumference	0.2	0.9	3.1	-0.6	-1.7	-1.1	1.0	-0.0	-0.8	-1.7	-0.9	-0.1	-1.2	-1.0	-1.0	-0.8	-0.8	-0.8	-0.5	-0.1	-0.9	-1.1	-0.8	-1.4	-0.4	-1.0	0.3	-1.2
Illnesses of siblings	0.2	0.2	1.2	-0.2	0.2	-0.2	-1.0	-0.2	0.1	0.3	-0.4	-1.1	-0.2	-0.4	-0.5	-0.2	-0.3	-0.3	-0.9	-0.2	0.4	-0.6	0.4	0.4	-0.3	0.2	-0.2	0.6
Arm fat percentage (right)	0.2	0.6	5.6	0.6	-0.3	0.6	2.4	1.5	0.1	-0.6	0.5	1.2	0.6	0.3	0.4	1.1	0.5	-0.2	1.1	0.9	0.5	0.1	-0.4	0.2	0.4	0.4	0.8	0.6
Pulse rate	0.2	0.3	1.3	0.6	0.5	0.1	-1.0	0.2	-0.2	-0.3	0.3	0.7	-0.2	0.3	0.4	-0.6	0.2	-0.0	-0.4	-0.0	-0.8	0.6	1.1	-0.3	0.5	0.8	0.1	0.4
Illnesses of mother	0.2	0.3	3.6	-0.1	0.0	-0.0	-1.9	0.0	-0.0	0.2	-0.4	-0.0	-0.2	-0.5	-0.4	0.1	-0.2	0.2	0.2	0.4	0.9	0.4	0.3	0.5	-0.2	-0.4	0.5	-0.7
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.1	0.1	0.2	0.1	-0.3	0.4	1.0	-0.6	0.7	1.1	0.2	0.8	0.6	-0.2	0.4	0.3	0.2	0.2	-0.0	0.9	0.7	-0.4	-0.0	0.3	-0.6	0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	3.4	-0.5	-0.4	-0.4	0.3	-0.6	-0.8	-0.5	-0.4	-0.2	-0.5	-0.3	-0.4	-0.6	-0.5	-0.3	-0.5	-0.4	-0.8	-0.1	-1.8	-0.5	-0.3	-1.0	-0.4	-0.2
Number of children fathered	0.2	0.3	1.1	0.1	0.1	0.7	-1.0	0.7	0.8	0.1	0.7	0.4	0.2	0.6	0.6	0.1	0.3	0.1	0.5	0.3	0.5	0.7	0.8	-0.0	-0.0	0.8	0.3	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.3	-0.1	0.0	0.2	0.4	-0.1	0.4	1.1	-0.3	0.1	0.4	-0.3	-0.3	0.8	-0.1	0.0	0.1	0.0	0.8	-0.6	0.3	0.6	-0.3	-0.4	-0.6	-0.3
Age at first live birth	0.2	0.3	1.0	-0.3	-0.4	-1.0	-0.3	-0.6	-0.6	-0.0	-0.6	-0.9	-0.6	-0.5	-0.5	-0.7	-0.3	-0.7	-0.5	-0.4	0.3	-1.0	-0.2	-0.7	-0.1	-0.1	0.5	-0.9
Shortness of breath walking on level ground	0.2	0.3	1.0	0.3	-0.5	-0.3	0.8	0.1	-0.3	-0.9	0.2	1.0	-0.2	0.4	0.2	-0.8	0.3	0.4	0.3	0.4	-0.2	0.1	0.4	-0.7	0.9	0.4	0.6	-0.9
Suffer from ‘nerves’	0.2	0.3	0.8	0.7	0.8	0.9	0.4	-0.2	0.8	0.9	0.6	0.1	0.5	0.5	0.6	0.3	0.5	0.7	0.6	0.6	-0.3	0.2	0.3	0.4	0.4	0.4	0.5	0.6
Leg pain on walking	0.2	0.2	2.1	0.0	-0.3	0.1	1.5	-0.4	0.2	-0.7	0.1	-0.0	-0.1	0.3	0.1	-0.4	0.2	0.3	-0.1	0.1	-0.9	0.1	0.6	-0.6	0.3	0.3	0.4	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.7	-0.4	0.0	0.0	-0.8	0.6	-0.6	-0.8	0.2	-0.8	-0.3	0.1	0.1	-0.7	-0.2	0.2	-0.4	-0.1	0.3	0.6	0.0	-0.1	-0.5	0.5	-0.4	0.7
Knee pain experienced in last month	0.2	0.3	2.0	-0.3	-0.5	-0.1	0.4	-0.0	-0.1	-0.9	-0.0	-0.1	-0.5	-0.1	-0.1	-0.3	-0.2	0.0	-0.3	-0.1	-0.8	0.5	0.2	-0.7	-0.0	1.4	0.8	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	2.0	-0.9	-0.4	-0.7	-0.6	-0.4	-1.0	-0.5	-0.6	-1.4	-0.8	-0.8	-0.7	-0.6	-0.8	-0.7	-0.2	-0.3	0.3	-0.7	-0.7	-0.2	-0.7	-0.4	0.5	-0.3
Arm fat percentage (left)	0.2	0.6	5.0	0.5	-0.4	0.6	2.2	1.5	0.0	-0.7	0.3	1.2	0.6	0.2	0.2	1.2	0.4	-0.2	1.2	0.8	0.7	0.1	-0.7	0.3	0.3	0.4	0.9	0.7
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.2	0.5	0.1	0.5	0.7	0.5	0.5	0.4	0.1	0.3	0.7	0.1	0.0	0.6	0.4	0.5	0.9	0.3	0.8	0.2	0.5	1.0	0.4	0.5	-0.7	1.1
Breast cancer (self-reported)	0.2	0.2	2.0	0.4	0.9	0.5	0.6	-0.1	0.3	-0.0	0.4	0.3	0.5	0.5	0.5	0.5	0.4	0.1	-0.2	-0.2	-0.3	-0.1	0.3	0.1	0.3	0.7	-1.4	0.3
Illnesses of father: None of the above (group 1)	0.2	0.2	1.9	-0.0	0.5	-0.3	-0.3	0.3	-0.2	-0.9	0.4	-0.3	-0.1	0.4	0.4	-0.4	0.1	-0.1	0.2	-0.2	-0.1	1.1	1.4	-0.1	-0.2	0.4	-0.7	-0.2
Smoking status: Current	0.2	0.4	2.1	-0.4	-0.3	-0.1	-0.4	-0.0	-0.2	-0.0	-0.8	0.4	-0.3	-0.8	-0.8	0.2	-0.5	-0.5	-0.6	-0.0	0.5	-0.7	-1.3	0.1	-0.7	-1.4	-0.6	-0.9
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.1	-0.5	-0.5	-0.2	-0.9	0.3	-0.3	0.3	-0.3	0.9	-0.3	-0.3	-0.4	-0.3	-0.4	0.0	0.1	0.0	0.6	-0.2	-0.9	-0.0	-0.3	-0.5	0.2	-1.0
Fractured/broken bones in last 5 years	0.2	0.2	0.6	0.7	0.3	0.2	0.2	0.6	0.6	0.1	0.4	0.3	0.6	0.5	0.4	0.5	0.6	0.6	0.4	0.6	0.3	0.6	0.4	0.6	0.7	0.5	0.3	0.5
Ever depressed for a whole week	0.2	0.2	0.9	-0.5	-0.4	-0.6	-0.0	-0.5	-0.7	-0.9	0.0	0.4	-0.5	-0.1	-0.0	-0.6	-0.4	-0.2	0.1	-0.2	-0.7	-0.1	-0.1	-0.8	-0.7	-0.8	-0.3	-0.5
Commuting to job workplace: Cycle	0.2	0.3	1.4	0.4	0.5	0.4	0.6	1.2	0.1	0.1	0.6	0.1	0.4	0.4	0.6	0.8	0.3	0.7	0.5	0.3	0.6	0.0	0.6	0.4	-0.2	0.2	0.8	0.6
Vascular/heart problems diagnosed by doctor	0.2	0.5	3.4	-0.5	0.3	-0.3	-1.0	0.1	0.0	0.3	-0.6	-0.4	0.2	-0.7	-0.6	0.7	-0.5	-0.6	-0.3	-0.2	0.7	-0.0	-1.8	1.0	-1.0	-0.7	-1.8	0.0
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.7	-0.6	-0.6	-0.4	0.3	-0.3	-0.7	-0.3	-0.6	-0.9	-0.2	-0.5	-0.6	0.2	-0.5	-0.7	0.0	-0.6	0.8	-0.8	-0.4	0.5	-0.6	-0.1	-0.7	-0.4
Alzheimer’s Disease (in mother)	0.1	0.1	0.9	-0.5	0.2	-0.2	-0.0	-0.3	0.3	-0.2	-0.2	-1.0	-0.2	-0.2	-0.4	0.1	-0.5	0.2	-0.6	-0.1	0.2	0.3	0.2	-0.0	-0.4	-0.1	-0.8	0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.8	-0.3	-0.1	-0.2	-0.4	-0.4	-0.4	0.3	-0.1	-0.7	0.1	-0.1	-0.1	0.4	-0.1	-0.1	0.7	0.1	0.7	-0.2	0.2	0.6	-0.4	-0.2	0.5	-0.9
Heel T-Score	0.1	0.9	3.4	-0.6	-1.1	-0.6	1.4	-1.4	-0.4	-1.1	-0.9	-1.1	-0.9	-0.7	-0.8	-0.9	-0.6	-0.8	-0.9	-0.9	-1.9	-1.3	-1.0	-1.3	0.0	-0.1	-0.0	0.4
BMI	0.1	0.6	6.2	0.3	-0.3	0.3	2.5	1.6	-0.0	-1.0	0.6	0.8	0.2	0.5	0.5	0.8	0.4	0.2	0.9	1.0	0.2	0.5	-0.2	-0.4	0.1	0.1	1.1	0.4
Waist Hip Ratio (WHR)	0.1	0.6	2.7	0.3	-1.1	-1.0	-0.8	0.0	-0.8	-0.7	-0.5	0.6	-0.9	-0.3	-0.3	-1.3	-0.2	0.4	0.0	0.6	-0.6	-0.6	0.0	-1.2	0.5	-0.6	1.6	-1.6
Systolic Blood Pressure	0.1	0.7	3.4	0.4	-0.7	-0.4	1.4	-0.7	-1.6	-0.9	-0.1	-0.2	-0.5	0.1	-0.1	-0.9	0.1	0.6	-0.2	-0.1	-1.0	-0.6	-0.5	-1.2	1.3	0.4	1.9	-1.0
Hypothyroidism (self reported)	0.1	0.3	2.1	-0.6	-0.6	-0.2	0.5	-0.5	-0.5	-0.2	-0.7	-0.6	-0.5	-0.6	-0.8	-0.2	-0.6	-0.6	-0.4	-0.3	-0.2	-0.5	-1.5	-0.2	-0.3	-0.9	0.0	-0.3
Hair Pigment	0.1	1.7	4.7	-1.9	-1.9	-1.7	-0.1	-0.7	-0.7	-0.3	-1.8	-0.8	-1.1	-2.0	-1.9	-0.6	-1.9	-1.4	-1.4	-1.7	-0.1	-1.7	-0.7	-0.2	-2.2	-1.2	-0.1	-0.6
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.7	0.2	0.8	0.4	-0.3	0.0	0.5	-0.2	0.8	0.4	0.2	0.5	0.8	0.2	0.3	0.8	0.4	0.8	-0.2	0.8	-0.4	-0.2	-0.1	-0.1	-0.0	0.1
Diabetes (father)	0.1	0.1	0.9	-0.2	0.1	0.1	0.1	-0.6	-0.3	0.2	0.0	-0.1	-0.2	-0.2	0.0	0.1	-0.2	-0.3	-0.1	-0.0	-0.8	0.5	-0.5	-0.2	-0.4	-0.2	-0.9	0.1
Townsend deprivation index at recruitment	0.1	0.1	1.3	-0.3	0.0	-0.1	-0.5	0.6	-0.0	-0.5	-0.1	1.1	0.0	-0.2	-0.1	0.3	-0.2	-0.4	-0.0	-0.2	0.5	0.6	0.2	0.1	-0.5	0.1	-0.0	-0.1
High blood pressure (mother)	0.1	0.1	1.5	0.2	-0.4	0.1	1.2	-0.1	-0.3	-0.0	-0.3	-0.2	0.2	-0.1	-0.2	0.3	0.1	-0.4	-0.2	-0.4	-0.2	-0.8	-0.4	0.0	0.2	0.1	0.5	0.3
Body mass index (BMI)	0.1	0.4	3.9	-0.4	-1.0	-0.2	2.0	0.7	-0.3	-1.4	-0.3	0.1	-0.5	-0.5	-0.5	0.1	-0.4	-0.5	-0.1	0.1	-0.3	-0.3	-0.9	-0.7	-0.5	-0.2	0.2	0.4
Trunk fat mass	0.1	0.4	2.5	-0.1	-1.0	-0.3	1.4	0.4	-0.9	-1.6	-0.3	0.3	-0.5	-0.3	-0.3	-0.2	-0.1	-0.9	0.3	0.1	-0.6	-0.6	-0.9	-0.9	0.1	-0.3	0.9	-0.6
Father’s age at death	0.1	0.1	0.5	0.2	-0.4	-0.0	-0.2	-0.7	0.1	0.4	-0.4	0.1	0.3	-0.4	-0.4	0.3	0.1	-0.1	-0.5	-0.2	0.0	-0.3	0.2	0.1	0.5	0.4	-0.3	0.1
Worrier / anxious feelings	0.1	0.2	1.2	-0.2	0.4	0.0	-0.2	0.6	0.4	0.3	0.2	0.5	-0.2	0.0	0.2	-0.2	-0.1	0.2	0.1	0.0	-0.2	0.7	0.5	-0.0	-0.3	0.6	0.6	1.1
Happiness	0.1	0.2	1.0	-0.6	0.0	-0.0	-0.6	-0.3	-0.1	-0.1	0.0	-0.5	-0.3	-0.3	-0.1	-0.1	-0.6	-0.4	0.1	-0.5	-0.3	0.3	0.4	0.1	-1.0	-0.4	-0.5	0.3
Arm fat mass (right)	0.1	0.5	2.3	-0.4	-1.2	-0.4	1.5	0.5	-0.7	-1.5	-0.5	0.0	-0.5	-0.6	-0.6	-0.1	-0.5	-1.0	0.0	-0.0	-0.4	-0.7	-1.1	-0.7	-0.4	-0.4	0.0	-0.1
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.9	0.1	-0.3	-0.4	0.3	-0.7	0.1	0.4	-0.0	0.1	-0.1	0.0	-0.1	-0.6	0.1	-0.2	-0.6	-0.4	-0.8	-0.7	0.1	-0.3	0.0	-0.3	-1.0	-0.5
High blood pressure (siblings)	0.1	0.2	0.9	-0.2	-0.8	-0.3	0.5	-0.6	-0.7	-0.6	-0.1	0.2	-0.2	-0.1	-0.1	-0.2	-0.2	-0.5	0.2	-0.3	-0.7	-0.5	-0.4	-0.5	-0.2	-0.1	-0.1	-1.0
Body fat percentage	0.1	0.5	4.7	0.6	-0.4	0.4	2.2	0.9	-0.1	-1.0	0.4	1.1	0.4	0.4	0.4	0.6	0.6	-0.2	0.9	0.7	-0.1	-0.0	-0.2	-0.3	0.7	0.4	1.1	0.2
Leg fat percentage (right)	0.1	0.3	3.1	-0.2	-1.1	-0.1	1.8	0.2	-0.2	-1.4	-0.2	0.3	-0.3	-0.3	-0.4	0.0	-0.2	-0.4	0.2	0.3	-0.4	-0.5	-0.4	-0.7	-0.1	-0.2	0.2	0.2
Worry too long after embarrassment	0.1	0.2	1.6	-0.5	-0.2	-0.6	-0.6	0.1	-0.9	-0.5	-0.1	-0.3	-0.7	-0.3	-0.1	-0.7	-0.5	-0.4	-0.2	0.1	-0.3	-0.3	-1.3	-0.5	-0.7	0.2	0.2	0.2
Medication: Allopurinol	0.1	0.2	0.5	0.4	-0.0	0.2	-0.3	-0.2	0.3	0.6	0.1	0.7	0.4	0.1	0.0	0.4	0.4	-0.1	-0.4	-0.1	0.1	0.5	0.4	0.6	0.7	0.6	-0.2	0.3
Whole body fat mass	0.1	0.4	2.4	-0.2	-1.0	-0.4	1.5	0.5	-0.7	-1.5	-0.2	0.2	-0.5	-0.3	-0.4	-0.2	-0.2	-0.8	0.1	0.1	-0.6	-0.6	-0.7	-0.9	-0.1	-0.2	0.4	-0.1
Leg fat mass (right)	0.1	0.5	3.1	-0.5	-1.4	-0.6	1.6	0.2	-0.5	-1.8	-0.5	-0.1	-0.7	-0.6	-0.7	-0.4	-0.5	-0.8	-0.2	-0.1	-0.8	-0.7	-0.5	-1.1	-0.4	-0.3	0.2	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.0	0.3	0.6	0.2	-0.3	0.6	0.8	1.0	0.3	0.8	0.4	0.4	0.4	0.1	0.4	0.4	0.4	0.2	0.5	0.6	-0.1	0.5	0.3	0.3	0.8	0.2
Arm fat mass (left)	0.1	0.4	2.5	-0.4	-1.1	-0.2	1.6	0.7	-0.5	-1.4	-0.5	0.1	-0.5	-0.6	-0.6	0.1	-0.4	-0.9	0.1	0.0	-0.2	-0.7	-1.1	-0.6	-0.4	-0.3	0.3	0.2
Ever taken oral contraceptive pill	0.1	0.1	1.4	0.2	-0.2	-0.2	-0.3	-0.1	-0.1	-0.4	0.2	-0.1	-0.1	0.2	0.3	-0.6	0.1	0.1	-0.1	-0.3	-0.3	-0.4	1.2	-0.5	0.0	0.5	0.5	0.2
Hearing aid user	0.1	0.1	0.8	-0.4	-0.7	-0.3	-0.4	-0.1	0.2	0.0	-0.3	-0.0	0.2	-0.2	-0.3	0.0	-0.1	-0.4	0.1	-0.4	0.3	-0.9	-0.1	0.5	-0.3	-0.5	-0.6	0.3
Mother’s age at death	0.1	0.1	0.8	0.3	-0.3	0.2	0.6	0.0	-0.0	0.0	0.2	0.4	0.3	0.3	0.2	-0.1	0.4	-0.2	0.1	-0.4	-0.2	-0.1	0.0	-0.3	0.6	0.6	-0.3	0.9
Financial situation satisfaction	0.1	0.2	0.8	-0.4	-0.0	0.2	-0.3	0.4	0.0	-0.2	-0.3	0.2	-0.3	-0.3	-0.3	0.2	-0.4	-0.4	0.5	-0.0	0.9	-0.1	-0.1	-0.1	-0.8	-0.8	0.7	-0.3
Leg fat percentage (left)	0.1	0.4	3.7	-0.2	-1.1	-0.0	1.9	0.5	-0.3	-1.5	-0.1	0.5	-0.2	-0.2	-0.3	0.0	-0.1	-0.3	0.4	0.4	-0.2	-0.4	-0.7	-0.7	0.0	-0.1	0.4	-0.0
Age started oral contraceptive pill	0.1	0.2	0.8	-0.1	0.2	-0.2	0.5	0.2	0.4	0.9	-0.2	-0.0	0.3	-0.3	-0.1	0.6	-0.1	-0.1	0.2	-0.1	0.9	-0.2	-0.8	0.4	-0.2	-0.5	-0.8	0.1
Diastolic blood pressure, automated reading	0.1	0.3	2.0	0.6	-0.0	0.0	1.0	0.3	-0.5	-0.4	0.3	0.0	-0.0	0.5	0.4	-0.5	0.3	0.4	-0.1	0.0	-0.9	-0.3	0.1	-0.3	1.0	0.9	1.4	-0.1
Leg fat mass (left)	0.1	0.6	3.5	-0.6	-1.4	-0.5	1.6	0.4	-0.7	-1.9	-0.4	0.0	-0.7	-0.5	-0.6	-0.4	-0.5	-0.8	-0.0	-0.0	-0.7	-0.7	-0.7	-1.2	-0.3	-0.3	0.4	-0.2

Hub : Genes

TMED8

Models

Trait associations