Hub : Genes

TMEM106A

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.2440	0.0890	1.1e-04	0.005	NA	0.017	NA	-0.002	1.5e-01	NA	3.6e-02	NA	4.1e-01
2	GTEx	Artery Coronary	0.1660	0.0770	1.3e-03	0.114	NA	0.114	NA	0.144	1.1e-04	NA	1.2e-04	NA	1.4e-05
3	GTEx	Artery Tibial	0.1563	0.0490	4.8e-10	0.135	NA	0.147	NA	0.156	9.3e-11	NA	1.4e-11	NA	2.9e-12
4	GTEx	Breast Mammary Tissue	0.1150	0.0550	2.0e-03	-0.003	NA	0.012	NA	0.001	5.0e-01	NA	7.9e-02	NA	2.8e-01
5	GTEx	Breast Mammary Tissue (Male)	0.0418	0.0607	2.5e-01	0.014	NA	-0.009	NA	-0.001	1.5e-01	NA	5.8e-01	NA	3.5e-01
6	GTEx	Cells EBV-transformed lymphocytes	0.4630	0.0850	7.7e-12	0.343	NA	0.337	NA	0.352	5.6e-12	NA	9.5e-12	NA	2.7e-12
7	GTEx	Heart Atrial Appendage	0.0770	0.0360	2.6e-03	-0.002	NA	0.002	NA	0.002	4.0e-01	NA	2.5e-01	NA	2.6e-01
8	GTEx	Nerve Tibial	0.1467	0.0618	3.4e-04	0.004	NA	0.031	NA	0.009	1.7e-01	NA	2.9e-03	NA	6.6e-02
9	GTEx	Pituitary	0.1500	0.0640	4.9e-04	0.118	NA	0.120	NA	0.142	7.0e-04	NA	6.4e-04	NA	2.0e-04
10	GTEx	Skin Not Sun Exposed Suprapubic	0.0700	0.0360	2.1e-03	-0.002	NA	0.025	NA	0.011	4.0e-01	NA	1.5e-02	NA	8.0e-02
11	GTEx	Small Intestine Terminal Ileum	0.1500	0.0720	6.7e-03	-0.013	NA	-0.013	NA	-0.009	8.2e-01	NA	8.7e-01	NA	5.6e-01
12	GTEx	Vagina	0.4140	0.1160	9.1e-03	0.037	NA	0.035	NA	0.064	4.9e-02	NA	5.6e-02	NA	1.5e-02
13	YFS	Blood	0.0160	0.0077	8.4e-04	0.001	0.012	0.008	0.012	0.006	1.3e-01	5.2e-05	1.1e-03	4.7e-05	4.3e-03
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0460	0.0410	4.1e-03	0.017	0.027	0.027	NA	0.017	3.6e-02	1.0e-02	1.1e-02	NA	3.6e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bipolar Disorder (2018)	0.2	0.3	1.0	-0.5	0.8	-0.7	0.3	-1.0	0.4	0.2	0.5	0.0	-1.0	-0.5	-0.3	-0.3	-0.6
Bipolar Disorder or Schizophrenia	0.4	1.0	2.9	-1.3	0.3	-1.4	-0.3	-0.4	1.4	0.2	-0.2	-0.9	-1.7	-1.2	0.1	-0.7	-1.6
Depressed Affect (Nagel 2018)	0.1	0.3	2.3	-0.2	-0.3	-0.4	0.2	-0.3	0.0	0.1	-1.5	-0.3	-0.7	0.6	0.1	0.2	-0.2
Depression (Nagel 2018)	0.6	0.9	2.6	-1.6	-0.9	-0.2	0.1	0.9	0.6	1.2	0.1	-0.8	-1.1	-0.6	-1.2	-1.5	-0.7
Intelligence (Savage-Jansen 2018)	0.3	0.9	4.3	0.5	-0.3	0.8	0.3	-1.4	-1.4	-0.1	-0.5	0.7	1.1	0.3	-2.1	0.1	1.2
Neuroticism (Nagel 2018)	0.2	0.5	1.4	-0.7	-1.1	-0.7	0.1	-0.4	0.7	-0.2	-1.2	-0.9	-1.2	-0.2	-0.3	0.0	-0.9
Schizophrenia (2018)	0.5	1.0	2.3	-1.2	-0.3	-1.3	-0.6	0.3	1.4	0.1	-0.7	-1.1	-1.4	-1.2	0.3	-0.6	-1.5
Schizophrenia vs Biploar Disorder	1.3	1.7	3.6	-0.9	-1.8	-0.8	-1.8	1.1	1.4	-1.9	-0.6	-1.8	-0.2	-1.7	-0.8	-0.0	-1.2
Worry (Nagel 2018)	0.7	1.4	3.4	-1.2	-1.4	-1.4	-0.3	-0.3	1.8	-0.4	-0.3	-1.7	-1.5	-1.4	-0.2	-0.4	-1.7
Alzheimer’s Disease (in mother)	0.8	0.9	4.0	0.1	-0.1	-0.4	-0.8	-1.8	0.3	-1.1	-0.8	-0.1	-0.9	-0.1	2.0	1.3	0.2
Alzheimer’s Disease (in father)	0.5	0.5	2.8	0.2	0.4	0.6	0.3	-0.6	0.2	0.3	1.7	-0.1	0.3	-0.0	0.8	-1.5	-0.1
Alzheimer’s Disease (including proxy)	0.5	0.7	6.4	0.1	0.3	0.1	0.5	-2.5	0.1	0.3	0.7	0.1	-0.5	0.3	1.2	-0.4	0.3
Crohns Disease (2017)	1.5	3.3	6.3	2.2	2.5	1.8	2.0	-0.3	-1.2	2.2	2.2	1.6	1.4	2.0	2.1	0.3	1.6
Irritable Bowel Disease (IBD)	0.9	2.2	4.8	2.1	2.2	1.5	1.0	-1.5	-0.6	0.9	2.2	1.4	0.7	1.4	2.0	0.7	1.2
Ulcerative Colitis (UC)	0.5	0.9	3.6	1.1	0.9	0.8	-0.2	-1.8	-0.0	-0.5	1.9	0.7	0.1	0.3	0.9	0.3	0.6
Major Depression (MDD)	0.5	0.6	2.8	-0.4	0.5	-0.7	-0.7	0.4	0.8	-0.4	0.2	-0.6	-1.7	-0.8	1.3	0.0	-0.7
Reaction Time	0.6	1.2	5.5	-1.0	0.1	-0.1	1.1	1.2	-0.1	2.4	0.3	0.4	1.4	0.2	-0.9	-2.0	-0.1
Verbal and Numeric Reasoning (VNR)	0.5	1.2	3.8	1.0	0.2	1.3	0.8	-2.0	-1.3	0.3	-0.8	1.1	1.2	1.1	-1.2	-0.2	1.4
Breast Cancer	0.3	0.6	2.9	0.5	0.6	1.0	0.4	0.3	-0.6	0.8	1.7	0.6	1.1	0.3	-0.3	0.1	0.9
Ovarian Cancer	1.7	2.3	5.9	-1.7	-2.4	-1.1	-1.3	0.2	1.0	-0.2	0.0	-1.5	-1.6	-1.8	-2.0	-2.4	-1.1
Prostate Cancer	1.0	1.4	4.7	1.4	-0.5	1.1	0.7	2.1	-0.9	0.0	0.9	0.1	1.8	0.6	-2.2	-0.0	0.8
Age at First Birth	0.7	1.0	4.1	-0.1	-1.3	-0.8	-0.3	1.7	0.1	-0.5	-1.4	-0.5	1.1	-0.5	-2.0	1.1	-0.4
Bipolar Disorder (2011)	0.5	0.5	2.2	-0.7	0.0	-0.7	-0.6	-0.6	1.0	0.1	0.2	-0.8	-1.5	-0.9	0.0	-0.1	-0.9
Body Mass Index (BMI) (2010)	1.8	2.4	5.3	2.3	0.8	1.9	-0.1	-0.8	-1.9	-0.5	1.5	1.5	1.2	1.8	1.2	2.3	2.0
Coronary Artery Disease (CAD)	1.1	1.3	3.2	-0.9	-0.4	-0.9	-1.6	-0.7	0.7	-1.8	-1.4	-1.1	-0.5	-1.2	1.8	0.4	-1.2
Crohns Disease (2012)	0.7	1.2	3.4	1.3	1.9	1.0	1.1	0.1	-1.0	1.4	0.5	1.3	1.0	1.1	1.0	0.1	0.9
Mean Putamen Volume	0.3	0.3	1.1	-0.2	-0.3	-0.7	-1.1	-0.5	0.6	-0.3	0.3	-0.4	0.2	-1.0	-0.8	-0.4	-0.6
Fasting Glucose	1.6	1.9	4.1	-0.9	-1.2	-1.6	-2.0	-0.9	2.0	-1.2	-1.3	-1.4	-1.4	-1.5	0.5	-0.3	-1.7
HbA1C	4.1	4.6	11.9	-2.9	-2.1	-2.3	-0.8	0.8	2.4	0.0	-1.5	-2.7	-1.9	-1.9	-1.6	-3.5	-2.7
HDL Cholesterol	1.2	2.1	4.9	2.2	1.6	0.8	0.2	-2.2	-1.3	0.4	0.7	1.6	1.4	1.5	1.0	2.2	1.2
LDL Cholesterol	0.3	0.5	1.2	0.6	0.1	0.4	0.5	-0.1	-1.0	1.0	-0.3	0.5	1.0	0.7	-1.1	1.1	0.7
Lupus	2.2	3.4	6.7	-2.0	-2.6	-2.0	-1.6	-0.6	1.8	-1.2	-2.3	-2.0	-1.9	-2.4	-1.3	-0.1	-2.1
Neuroticism (2016)	0.2	0.3	1.1	-0.4	-0.3	-0.5	-0.0	0.4	1.1	-0.5	-0.3	-0.7	-0.7	-0.7	0.1	0.1	-0.9
Primary Biliary Cirrhosis	0.3	0.4	1.6	-0.4	-0.7	-0.7	-0.7	-0.2	0.5	-0.9	-1.3	-0.7	-0.8	-0.1	0.3	0.2	-0.4
Rheumatoid Arthritis	0.3	0.4	1.0	-0.2	-0.9	-0.7	-0.8	0.4	0.5	-1.0	-0.5	-0.6	0.0	-0.6	0.6	0.6	-0.4
Schizophrenia (2014)	1.6	3.6	8.0	-2.1	-1.3	-2.5	-1.5	0.9	2.8	-0.6	-0.8	-2.2	-2.1	-2.5	-1.2	-1.2	-2.8
Triglycerides	3.4	5.5	11.4	-3.1	-3.4	-2.0	-0.6	2.3	2.2	-0.3	-1.8	-2.4	-2.6	-2.4	-2.8	-2.5	-2.4
Type 2 Diabetes (T2D) (2012)	1.9	2.2	4.7	-1.6	-0.6	-1.4	-2.2	0.9	1.2	-1.8	-1.9	-1.3	-1.6	-1.9	1.0	-0.4	-1.8
Ulcerative Colitis	0.4	0.6	5.6	0.3	0.3	-0.3	-0.8	-2.4	0.1	-0.7	0.4	0.4	-0.2	0.2	0.1	0.9	-0.0
Blood Eosinophil Count	1.8	13.8	24.8	5.0	2.8	4.7	-0.0	3.6	-4.0	-2.3	3.2	3.7	4.9	3.0	2.7	4.3	4.8
Blood Platelet Count	0.1	1.4	11.9	-0.6	-1.3	-0.7	-0.4	3.5	-0.1	0.0	-1.4	-0.4	0.1	0.5	-1.5	-0.1	-0.1
Blood Red Count	0.1	0.8	4.4	-0.2	-1.0	-0.5	-1.0	2.1	0.4	-0.5	-1.4	-0.8	0.6	0.0	-0.8	0.5	-0.4
Blood White Count	2.8	21.0	45.2	6.2	2.7	6.7	3.2	1.2	-6.4	1.4	2.9	4.8	6.0	6.4	0.2	-0.1	6.4
Heel T-Score	4.2	33.2	70.6	-6.0	-6.6	-6.2	-4.7	2.4	5.0	-6.9	-4.3	-5.2	-8.4	-6.3	-6.0	-4.6	-5.8
BMI	0.9	5.4	12.8	2.9	-0.3	3.6	-0.9	0.7	-3.3	-2.2	0.4	1.7	2.9	3.1	1.5	1.1	3.5
Height	0.4	7.6	56.9	1.7	-1.0	2.6	-2.0	-7.5	-0.1	-3.5	4.2	0.2	-0.9	-1.0	0.4	0.6	1.4
Waist Hip Ratio (WHR)	0.9	4.3	24.9	-1.9	-2.2	-1.8	0.1	2.3	0.1	1.0	-3.7	-0.9	-0.3	-0.4	-5.0	-1.0	-1.0
Systolic Blood Pressure	0.8	3.8	8.6	-1.4	-1.8	-2.2	-2.5	1.6	2.1	-2.1	-1.5	-2.2	-0.8	-2.9	-2.2	-0.2	-1.9
Smoking Status	1.5	3.6	7.8	-2.3	-1.4	-2.0	-0.2	-2.7	1.9	1.2	0.4	-1.9	-2.3	-1.7	-1.6	-2.8	-2.0
Allergy or Eczema	0.4	1.0	5.4	0.3	1.0	-0.4	-0.2	1.2	0.1	-0.5	-1.6	0.5	-0.6	0.2	1.6	2.3	0.1
Cardiovascular Disease	0.8	2.5	5.5	-1.8	-2.2	-1.3	-1.8	2.4	1.2	-1.5	-1.3	-1.8	-0.9	-1.9	-1.3	-0.9	-1.2
Hypothyroidism (self reported)	0.4	1.0	3.5	-0.2	-0.1	-0.7	-1.1	1.3	1.4	-0.4	0.9	-1.2	-0.5	-0.9	1.9	0.7	-1.0
Respiratory disease	0.4	0.9	4.8	0.4	1.9	0.4	0.3	1.0	-0.2	0.9	0.2	0.9	0.1	0.5	2.2	0.6	0.8
Type 2 Diabetes (T2D) (2018)	1.3	2.4	11.4	-1.0	-2.0	-0.6	-2.1	3.4	0.6	-2.0	-2.0	-1.5	0.5	-0.7	-0.9	0.3	-0.6
Lung FEV1/FVC ratio	0.5	2.7	5.6	1.8	-0.5	1.8	0.5	1.6	-2.4	-1.0	-2.1	1.6	1.1	0.9	-2.3	1.5	2.3
Lung FVC	0.5	2.7	17.2	-0.8	0.2	-0.7	1.9	-0.4	1.0	2.0	1.6	-0.5	-1.6	-0.4	-1.8	-4.2	-1.2
Neuroticism	0.2	0.5	1.1	-0.8	-0.5	-0.7	0.0	-0.3	0.7	-0.5	-0.9	-1.0	-1.1	-0.0	1.0	0.1	-0.8
Chronotype (morning person)	0.5	1.2	6.1	-0.6	-0.9	-0.4	-1.3	2.5	0.1	-1.9	-1.3	-0.6	0.7	-0.8	-1.0	0.5	-0.2
Hair Pigment	0.0	1.2	4.6	0.3	-1.2	-0.5	-2.1	0.6	0.4	-1.8	-1.1	-0.6	0.4	-1.2	-1.5	1.4	-0.3
Tanning	0.1	1.6	5.3	-1.4	-0.2	-1.8	0.5	-0.1	1.3	0.3	-0.1	-0.9	-2.3	-1.4	-0.7	-1.8	-1.6
Hand grip strength (left)	3.2	8.4	16.9	-2.6	-2.3	-3.2	-4.0	-0.6	3.5	-3.1	-0.9	-3.1	-4.1	-3.9	-0.6	-1.4	-3.4
Number of treatments/medications taken	0.7	1.3	3.0	-1.2	-1.0	-1.5	-1.2	1.2	1.0	-0.6	-1.7	-1.2	-1.1	-1.4	-0.1	-0.2	-1.4
Average weekly spirits intake	0.6	0.7	1.9	-1.4	-0.8	-0.9	-0.1	0.5	1.1	0.5	-0.6	-0.7	-0.5	-1.2	-0.5	-1.2	-1.0
Sensitivity / hurt feelings	0.9	1.5	7.1	-1.2	-1.8	-1.2	-0.7	0.1	0.7	-1.0	-2.7	-1.4	-1.2	-0.5	-0.4	-0.1	-1.1
Frequency of depressed mood in last 2 weeks	0.6	0.9	7.8	-0.4	0.1	0.3	1.6	-0.1	0.0	2.8	0.4	0.1	-0.7	0.6	-0.6	-0.6	-0.0
Hearing difficulty/problems: Yes	0.6	0.9	3.3	0.7	1.8	0.3	1.4	-0.2	-0.4	1.6	0.6	1.2	0.6	1.0	0.8	-0.1	0.3
Relative age of first facial hair	0.6	1.3	2.7	-1.6	-1.4	-0.8	-1.1	0.6	1.2	-0.8	-1.3	-0.8	-0.9	-1.3	-0.6	-1.4	-1.4
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	2.5	-1.2	-1.3	-1.0	-0.0	1.6	1.0	-0.4	-1.1	-1.0	-0.7	-0.7	-1.2	-0.0	-1.1
Ever used hormone-replacement therapy (HRT)	3.4	4.3	10.1	2.4	1.2	3.2	1.3	-0.1	-3.0	1.0	1.9	2.1	3.0	2.3	-0.3	1.1	2.8
Ever had hysterectomy (womb removed)	1.6	1.8	5.4	1.1	1.3	1.3	1.2	1.2	-1.4	1.5	1.5	1.2	2.3	1.3	0.5	-0.2	1.5
Systolic blood pressure, automated reading	0.2	0.4	1.3	0.6	-0.2	0.3	-1.0	1.1	0.0	-0.7	0.5	-0.3	1.0	-0.6	-1.1	0.1	0.3
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	5.1	-1.2	-1.6	-0.5	0.5	1.1	0.7	0.4	0.5	-1.1	-0.0	-0.2	-2.0	-2.2	-0.8
Angina	0.8	1.1	2.8	-0.1	-1.3	-0.4	-1.3	1.7	0.3	-0.9	-1.5	-0.8	-0.3	-1.3	-1.7	0.1	-0.4
Medication for hormone replacement therapy	0.2	0.2	0.9	0.4	0.2	0.8	-0.2	-1.0	-0.4	-0.1	0.3	-0.2	0.9	0.4	-0.1	-0.5	0.1
Vitamin and mineral supplements	2.7	3.6	6.8	1.8	1.9	2.2	2.6	-0.7	-2.1	2.2	1.1	2.5	2.1	2.2	-0.2	-0.9	2.2
Supplements: Zinc	2.8	3.1	6.2	-1.6	-1.2	-2.5	-2.0	0.3	2.4	-0.9	-1.0	-2.2	-2.1	-2.4	-0.5	0.0	-2.3
Medication: Co-codamol	0.4	0.5	1.7	0.0	0.0	0.2	-0.7	1.3	-0.1	-1.3	-1.3	0.4	0.3	-0.1	0.6	0.9	0.2
Medication: Metformin	1.8	2.6	9.5	-0.9	-2.6	-0.7	-2.2	1.7	0.9	-3.1	-1.8	-1.9	-0.6	-0.6	-1.3	0.4	-0.8
Diabetes (father)	0.3	0.3	0.9	-0.0	-0.7	0.1	-0.9	0.4	0.1	-0.7	-0.8	-0.6	0.8	-0.7	-0.1	0.4	0.0
Diabetes (mother)	0.5	0.7	3.1	0.9	0.6	0.6	0.5	1.8	-0.7	0.5	-0.4	0.0	0.9	1.4	-0.0	0.9	0.5
Severe depression (siblings)	3.0	3.3	8.0	-2.8	-1.2	-2.6	-0.7	0.2	2.4	0.0	-1.2	-2.0	-1.5	-2.5	-0.8	-1.6	-2.6
Pack years adult smoking proportion	0.2	0.4	1.1	-0.6	-0.7	-0.1	-0.8	-0.5	0.5	-1.1	0.1	-0.7	-0.9	-0.7	-0.1	-0.1	-0.4
Impedance of leg (right)	0.6	3.1	7.4	-2.1	-1.3	-2.7	0.0	1.5	2.4	0.5	-0.8	-1.8	-0.7	-1.8	-2.6	-1.1	-2.6
Leg fat-free mass (left)	0.6	3.3	9.7	1.9	-0.3	3.1	-1.0	-2.5	-2.1	-2.3	1.2	1.0	0.7	1.5	1.4	1.0	2.6
Trunk fat percentage	1.0	4.1	11.6	2.0	-0.2	3.4	0.9	-0.7	-2.7	-0.3	1.8	1.5	2.9	2.9	1.3	-0.5	2.9
Hand grip strength (right)	4.2	11.3	22.9	-3.2	-2.6	-3.8	-4.3	-0.2	4.2	-3.5	-0.7	-3.6	-4.8	-4.4	-0.2	-1.9	-4.2
Townsend deprivation index at recruitment	0.9	1.3	4.3	0.7	1.9	1.0	0.9	-0.7	-0.9	1.0	0.9	1.0	1.2	0.9	2.1	1.1	0.7
Current tobacco smoking	1.1	1.8	7.5	-0.5	0.5	-0.1	1.3	-2.3	0.5	2.7	1.5	0.0	-0.8	-0.3	-0.5	-2.7	-0.2
Average weekly fortified wine intake	3.5	4.1	9.6	-2.8	-1.3	-2.5	-1.2	1.9	2.9	-0.3	-0.5	-1.9	-2.3	-3.1	-1.2	-1.0	-2.6
Maternal smoking around birth	0.3	0.5	4.9	0.1	0.9	0.3	-0.1	0.3	0.2	-0.1	-0.4	0.1	-0.5	-0.2	2.2	-0.5	0.0
Fed-up feelings	0.2	0.3	1.6	0.1	-0.3	0.1	0.9	-1.3	-0.3	0.8	-0.4	0.2	-0.3	0.9	0.1	-0.2	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.1	0.5	0.5	1.5	1.0	-0.0	-0.9	0.9	1.0	1.0	0.2	1.3	1.0	-0.1	1.0
Relative age voice broke	2.3	3.5	6.6	-2.6	-2.1	-1.8	-2.2	0.4	2.3	-1.5	-1.9	-1.9	-1.8	-2.3	-0.2	-0.7	-2.4
Taking other prescription medications	0.5	0.8	1.8	-0.5	-0.7	-1.2	-1.1	1.4	0.8	-0.7	-1.1	-0.9	-1.0	-0.7	0.3	0.5	-1.0
Age when periods started (menarche)	0.6	1.4	3.3	-0.6	-1.8	-1.1	-1.6	-0.6	1.2	-1.4	-0.2	-1.1	-0.5	-1.4	-1.8	0.9	-0.8
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.6	-0.3	0.3	-0.0	1.2	1.4	-0.5	1.6	-0.7	0.4	1.0	0.5	-1.1	-1.2	0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	7.1	-1.1	-2.4	-1.3	-1.4	0.6	1.1	-2.7	-1.4	-0.9	-2.0	-1.7	-1.5	-0.5	-1.0
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.6	-0.4	-0.2	-0.2	-0.5	0.3	0.4	-0.4	0.0	-0.4	-0.5	-0.8	0.6	0.1	-0.3
Qualifications: CSEs or equivalent	2.0	2.7	5.7	-1.7	-1.2	-1.7	-2.1	0.8	1.8	-2.1	-2.4	-1.6	-1.4	-1.8	1.0	1.0	-1.6
Serious illness, injury or assault to yourself	0.7	0.9	2.8	0.4	-0.3	0.9	-0.5	1.6	-0.9	-0.8	-0.8	0.5	1.7	0.4	0.6	1.5	0.9
High blood pressure	0.2	0.6	3.6	0.2	-0.6	0.4	0.4	-0.7	-0.8	0.8	-0.7	0.3	0.4	0.3	-1.9	-0.8	0.6
Hayfever, allergic rhinitis or eczema	0.6	1.2	5.3	-0.3	-0.1	-0.8	-0.7	1.6	0.5	-1.2	-2.0	-0.2	-1.2	-0.3	0.7	2.3	-0.3
Multivitamins +/- minerals	0.4	0.5	2.0	0.4	-0.8	-0.3	-1.2	0.4	0.1	-1.0	-0.2	-0.6	-0.5	-0.6	-0.2	1.4	-0.0
Stomach or abdominal pain in last month	0.2	0.3	0.8	-0.5	0.4	-0.8	0.9	-0.1	0.5	0.3	-0.6	0.2	-0.9	0.0	0.4	-0.6	-0.6
Supplements: Glucosamine	1.4	1.9	3.7	1.6	0.8	1.4	-0.2	1.8	-1.4	-0.8	1.6	1.3	1.9	0.9	1.0	1.9	1.5
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.7	-1.0	-1.2	-1.0	-0.9	1.9	0.7	-1.5	-1.7	-0.8	-1.1	-0.7	-1.2	-0.5	-0.8
Medication: Atenolol	0.1	0.1	1.2	-0.0	-1.1	-0.0	0.1	0.4	-0.0	-0.3	-0.0	-0.5	-0.3	0.1	-0.4	-0.3	0.2
Medication: Levothyroxine sodium	0.4	0.6	3.9	0.8	0.5	0.5	-0.1	0.6	0.4	-0.2	1.4	-0.2	0.6	0.1	2.0	0.6	0.1
Sitting height	0.9	6.5	14.7	3.4	0.6	3.8	-0.6	-3.7	-2.5	-2.5	2.1	2.2	1.4	1.7	0.7	3.4	3.4
Chronic bronchitis/emphysema (father)	0.1	0.2	1.1	0.1	-0.1	0.1	-0.4	-1.0	-0.0	-0.5	0.3	-0.2	-0.3	-0.1	0.6	0.5	0.1
High blood pressure (mother)	1.6	2.2	9.5	0.6	1.8	0.5	2.9	0.7	-0.6	3.1	1.4	1.1	1.0	1.5	-0.3	-1.3	0.4
Body mass index (BMI)	0.8	3.5	9.5	2.0	-0.1	3.1	0.3	0.4	-2.7	-0.4	0.9	1.2	2.4	3.0	1.6	-0.1	2.8
Impedance of leg (left)	0.6	3.0	8.3	-2.0	-1.0	-2.9	0.2	0.9	2.5	0.6	-1.0	-1.5	-0.9	-2.0	-2.2	-1.0	-2.6
Leg predicted mass (left)	0.6	3.3	9.9	1.9	-0.3	3.1	-1.1	-2.4	-2.1	-2.3	1.2	1.0	0.8	1.5	1.5	1.1	2.6
Trunk fat mass	1.0	4.3	13.2	2.2	-0.3	3.6	0.5	-1.3	-2.8	-0.9	1.9	1.5	2.5	2.8	1.2	-0.3	3.1
Waist circumference	0.9	3.3	8.8	1.8	-0.3	3.0	0.7	0.2	-2.9	-0.0	0.8	1.4	2.5	2.8	0.3	-0.0	2.9
Number of incorrect matches in round	1.0	1.7	5.1	0.1	-0.6	-1.1	-2.3	-0.3	1.4	-1.8	-1.1	-0.9	0.3	-2.1	-0.8	1.6	-1.3
Past tobacco smoking	0.7	1.4	5.2	1.9	0.2	1.3	-0.8	0.9	-0.9	-1.1	-0.2	0.6	0.9	0.8	1.0	2.3	1.4
Alcohol usually taken with meals	0.3	0.4	1.9	0.2	-0.3	-0.1	-0.0	1.4	-0.0	-0.9	-0.7	-0.7	0.2	-0.1	-0.7	1.2	0.0
Nervous feelings	0.2	0.4	1.1	0.8	-0.3	1.1	0.8	-0.9	-0.5	0.1	1.0	0.4	0.3	0.4	0.0	0.2	0.9
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	5.6	-1.9	-1.7	-1.5	-0.7	0.2	2.0	-0.7	-1.3	-2.0	-2.4	-1.4	-0.8	-0.9	-1.8
Hearing difficulty/problems with background noise	0.9	1.4	3.9	0.7	1.8	0.8	2.0	1.4	-0.8	1.4	1.0	1.5	0.5	1.2	0.9	-0.4	0.7
Hair/balding pattern: Pattern 2	0.8	1.0	5.1	-0.6	-0.6	-1.1	-1.1	0.3	0.9	-0.7	-2.3	-0.6	-1.4	-1.1	-0.1	0.6	-0.8
Had menopause	9.8	12.2	25.7	4.0	3.0	4.6	3.2	-0.9	-3.9	1.8	5.1	3.9	3.7	3.6	2.1	2.3	4.3
Had other major operations	0.3	0.4	1.8	-0.8	-1.4	-0.2	0.0	0.7	0.4	0.4	0.2	-0.3	0.1	-0.4	-1.0	-0.7	-0.1
Forced vital capacity (FVC)	0.4	1.5	6.4	-0.5	-1.0	-0.6	-0.5	-2.3	1.2	-1.1	0.6	-0.9	-2.5	-1.2	-0.6	-1.1	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	1.3	2.9	8.3	-1.4	-2.2	-1.6	-1.4	0.3	1.5	-2.9	-1.3	-1.2	-2.2	-1.9	-2.1	-0.9	-1.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.1	-0.2	0.8	0.3	0.5	-0.3	0.1	0.7	0.1	0.0	-0.6	0.4	1.0	-1.0	-0.2
Qualifications: None of the above	0.9	2.0	5.7	0.6	1.3	1.2	1.8	-0.3	-0.8	2.1	2.4	1.2	1.5	1.1	1.9	-1.2	0.7
Financial difficulties in last 2 years	0.6	0.8	2.7	-0.1	0.4	0.8	1.0	-0.8	-0.9	1.6	-0.6	0.7	0.6	1.0	0.0	-1.5	0.5
Mouth/teeth dental problems	0.7	1.1	9.2	0.3	-1.1	-0.6	-0.0	0.9	-0.2	-0.5	-1.2	-0.2	0.0	-0.8	-3.0	1.0	-0.1
Heart attack	2.0	2.5	6.6	-1.1	-2.1	-1.6	-0.9	2.6	1.2	-1.3	-2.2	-1.7	-1.2	-0.9	-2.2	-0.4	-1.2
Allergy	0.4	1.0	4.2	0.6	-0.1	0.6	0.5	-1.5	-0.5	0.8	2.1	0.2	1.2	0.3	-1.2	-1.6	0.3
Pain all over the body in last month	0.2	0.2	1.1	0.6	0.1	0.6	-0.1	0.6	-0.4	-0.2	-0.2	0.0	-0.4	0.5	1.0	0.6	0.2
Diabetes (self-reported)	0.8	1.3	4.3	-0.7	-2.1	-0.1	-1.5	1.3	0.2	-1.3	-1.2	-1.1	0.1	-0.3	-2.0	-0.3	-0.3
Hayfever/allergic rhinitis (self-reported)	1.0	1.4	2.8	1.4	1.1	0.9	0.9	1.2	-1.1	-0.7	0.1	1.4	0.1	1.5	1.7	1.5	1.3
Medication: Ramipril	1.8	2.4	6.5	1.9	0.7	1.9	1.1	-0.1	-2.1	0.7	1.2	1.7	2.0	2.0	-0.5	0.6	2.6
Medication: Simvastatin	0.4	0.7	3.1	-0.2	-1.2	-0.1	-1.1	0.2	-0.3	-1.2	-1.8	-0.5	0.3	-0.4	-1.1	0.1	0.1
Fluid intelligence score	0.1	0.3	1.9	0.0	-0.3	0.2	0.3	-1.4	-0.1	0.5	-0.4	-0.0	0.2	0.4	-1.0	-0.7	0.3
Illnesses of siblings	0.3	0.4	2.2	0.2	1.5	-0.8	0.0	0.7	0.7	0.3	0.5	0.2	-0.3	-0.1	1.1	0.6	-0.3
Neuroticism score	0.1	0.2	0.9	0.1	-0.2	-0.1	0.6	-0.7	-0.1	-0.1	-1.0	-0.2	-0.6	0.5	0.4	0.8	0.0
Weight	0.8	3.8	12.5	2.1	-0.5	3.5	-0.5	-1.8	-2.6	-1.8	1.6	1.2	1.6	2.4	1.3	0.2	3.0
Impedance of arm (right)	0.1	0.6	2.0	-1.4	-0.1	-1.0	0.6	-0.3	1.2	0.4	0.3	-0.5	-0.4	-0.8	0.1	-1.3	-1.1
Arm fat percentage (right)	0.9	3.6	10.7	1.6	-0.3	3.0	0.9	0.6	-2.6	-0.1	1.1	1.1	2.7	3.3	1.5	-1.2	2.6
Trunk fat-free mass	0.3	1.9	5.8	1.3	-0.6	2.0	-1.4	-2.4	-1.1	-2.4	1.2	0.2	-0.2	0.7	0.5	0.9	1.6
Hip circumference	1.0	4.5	11.7	2.4	0.5	3.4	0.4	-1.6	-2.4	-0.8	2.3	1.3	2.0	2.4	3.1	0.6	2.9
Time employed in main current job	0.4	0.4	1.2	0.6	-0.1	0.7	0.8	0.2	-1.1	0.6	0.6	1.0	0.1	0.7	-0.5	-0.0	0.9
Alcohol intake versus 10 years previously	0.3	0.4	1.3	-1.1	-0.2	-0.5	-0.2	0.6	0.7	-0.4	-1.0	-0.9	-0.2	-0.4	0.3	-0.4	-1.0
Father’s age at death	0.6	0.9	6.6	0.1	-0.6	-0.2	0.5	-0.8	-0.0	0.9	1.2	-0.2	1.0	0.2	-2.6	-0.8	0.0
Worrier / anxious feelings	1.3	2.5	6.1	-1.7	-1.6	-1.9	-0.1	-0.5	2.2	-0.4	-2.5	-2.1	-1.6	-1.7	-1.0	-0.3	-1.9
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	3.1	-1.7	-0.4	-1.1	0.8	-0.3	1.1	1.1	-0.9	-1.0	-1.4	-0.8	-0.8	-1.8	-1.1
Falls in the last year	1.1	1.4	3.6	-1.1	-1.1	-1.1	-0.8	-0.1	1.5	-1.9	-0.3	-1.5	-1.6	-1.7	-0.4	-0.7	-1.2
Hair/balding pattern: Pattern 3	0.9	1.4	7.0	0.5	0.1	0.6	2.0	0.4	-1.0	1.3	0.8	0.9	1.2	0.9	-2.6	-0.8	0.9
Number of live births	0.4	0.5	2.1	0.0	0.9	0.2	0.8	1.3	-0.2	0.7	-0.3	0.5	0.4	0.7	1.4	-0.8	0.1
Forced expiratory volume in 1-second (FEV1)	0.5	1.6	4.7	-0.6	-1.7	-0.7	-1.1	-1.1	1.0	-2.0	-0.7	-1.0	-2.2	-1.5	-1.4	-0.8	-0.7
Pulse rate	0.6	1.1	2.5	-1.1	-0.7	-0.9	0.9	-1.6	1.0	1.5	-0.1	-1.0	-0.8	0.1	-0.8	-1.6	-1.1
Happiness	1.3	1.5	3.4	0.7	0.5	1.3	1.8	-1.7	-1.6	1.4	0.3	1.2	0.8	1.8	-0.6	-0.5	1.5
Noisy workplace	0.5	0.7	4.0	0.4	1.4	0.1	0.4	-0.7	0.2	0.0	1.1	0.5	-0.4	0.7	2.0	0.2	-0.0
Qualifications: A levels/AS levels or equivalent	1.5	3.2	8.1	2.8	1.5	1.9	1.1	-0.3	-2.5	0.1	-0.4	2.0	1.8	1.8	0.1	2.4	2.6
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	-0.2	0.5	-0.1	-0.2	-0.1	0.2	0.4	0.7	-0.0	-0.3	0.3	0.2	-0.6	-0.3
Mouth/teeth dental problems: Dentures	0.4	0.6	3.3	-0.9	-0.1	-0.3	-0.3	-1.1	0.6	0.3	0.8	-0.2	-0.2	-0.2	1.8	-1.1	-0.5
Asthma	0.5	0.9	7.2	0.1	1.7	0.1	-0.1	1.4	0.1	-0.1	-0.6	0.5	0.2	-0.1	2.7	0.6	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.0	-0.5	-0.9	-0.6	0.1	-0.8	0.9	-0.5	-1.0	-1.0	-1.4	-0.7	-0.5	-0.3	-0.6
Medication: Cholesterol lowering	0.8	1.2	3.3	0.9	-0.5	1.2	-0.7	0.8	-1.3	-1.1	-1.8	0.6	1.2	0.7	-1.3	1.0	1.4
Depression (self-reported)	0.3	0.4	3.0	-0.0	0.7	-0.1	1.2	0.1	0.1	1.7	-0.3	0.0	0.1	0.2	-0.4	-0.8	-0.2
Medication: Lansoprazole	1.5	1.7	9.2	-1.0	-1.2	-1.2	-1.5	1.1	0.7	-1.2	-3.0	-1.2	-0.9	-1.0	-0.8	0.3	-1.0
Prospective memory result	0.6	0.7	1.5	-0.9	-0.4	-1.1	-1.0	-1.1	1.2	-0.2	0.2	-0.6	-0.6	-1.0	0.7	1.2	-1.0
Lung cancer (father)	0.4	0.5	1.4	0.5	0.4	0.2	1.0	0.7	-0.1	1.0	0.4	0.6	1.1	0.6	0.4	-1.2	0.1
Illnesses of mother	2.2	2.7	9.1	-1.0	-2.1	-1.2	-2.9	0.7	0.9	-3.0	-1.8	-1.4	-0.8	-1.4	-0.5	1.8	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	1.6	0.2	-0.5	0.1	-0.1	-0.2	-0.1	-1.2	-0.3	-0.0	-0.7	-0.5	-0.8	-0.6	0.1
Pulse wave Arterial Stiffness index	1.1	1.3	5.8	0.4	0.7	0.6	2.0	-0.4	-1.0	2.4	0.4	1.0	1.0	1.1	-1.1	-0.8	0.8
Impedance of arm (left)	0.1	0.5	1.3	-0.7	0.8	-0.4	1.2	-0.8	0.7	0.9	1.1	0.2	0.0	-0.6	0.3	-1.0	-0.5
Arm fat mass (right)	0.8	3.2	10.0	1.7	-0.7	3.2	0.1	-0.5	-2.5	-1.1	1.3	1.0	1.9	2.8	1.4	-0.5	2.7
Trunk predicted mass	0.3	1.9	6.0	1.4	-0.6	2.1	-1.4	-2.2	-1.1	-2.5	1.1	0.2	-0.2	0.7	0.5	1.0	1.6
Standing height	0.4	3.7	24.7	0.1	-1.3	1.2	-1.9	-5.0	0.4	-3.4	1.8	-0.5	-1.7	-1.4	-0.4	0.6	0.4
Length of working week for main job	0.7	0.8	3.3	-0.7	0.4	0.8	1.0	-0.9	-0.2	0.4	1.8	0.1	-0.9	0.8	-0.3	-1.8	0.1
Exposure to tobacco smoke at home	0.3	0.4	0.9	-0.9	-0.7	-0.7	-0.0	0.5	0.8	0.3	-0.6	-0.8	-0.2	0.0	0.2	-0.7	-0.9
Breastfed as a baby	0.7	0.9	5.9	-0.7	-0.2	-0.6	0.4	-2.4	0.3	1.0	0.1	0.0	-1.3	-0.2	-1.5	-0.6	-0.4
Tense / ‘highly strung’	2.9	4.8	9.2	-2.5	-2.5	-2.4	-1.5	-2.3	3.0	-1.0	-1.0	-2.5	-2.7	-2.6	-0.9	-1.3	-2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.7	-1.0	-0.7	0.0	0.1	-0.3	0.1	0.4	0.1	-0.5	-1.2	-0.3	-1.3	-0.8	-0.5
Hair/balding pattern: Pattern 4	0.6	1.6	4.0	0.6	1.4	1.6	1.5	-0.5	-0.5	1.8	1.4	1.3	2.0	0.7	0.9	-0.9	1.1
Birth weight of first child	0.3	0.5	2.9	-0.1	0.3	-0.5	0.7	-1.7	0.3	0.5	-0.9	0.1	-1.4	0.0	-0.4	-0.3	0.1
Peak expiratory flow (PEF)	1.0	2.4	7.3	-0.9	-2.3	-1.1	-2.2	0.2	0.8	-2.7	-1.4	-1.3	-1.4	-1.9	-1.9	0.5	-0.8
Pulse wave reflection index	0.4	0.4	0.9	0.7	0.7	0.2	0.8	0.1	-0.9	0.8	0.8	0.7	0.4	0.7	0.4	0.7	0.7
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.9	-0.9	0.0	-0.6	0.5	0.3	0.6	0.6	0.5	-0.2	-1.1	-0.1	-0.0	-1.7	-0.6
Loud music exposure frequency	0.7	0.8	2.9	-0.3	0.3	-1.1	-0.0	-0.5	1.0	-0.0	-1.5	-0.4	-1.1	-0.4	1.7	0.4	-0.9
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	2.6	0.7	1.2	0.1	0.3	0.5	-0.7	0.2	-1.6	0.6	-0.6	0.6	0.0	0.5	0.6
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.2	0.1	0.7	0.6	0.2	-1.5	-0.4	0.6	0.6	0.4	0.6	0.5	0.5	-0.4	0.5
Blood clot in the leg (DVT)	0.1	0.2	0.8	0.1	-0.2	0.5	-0.7	-0.9	-0.3	-0.7	-0.2	-0.1	-0.0	0.2	0.2	0.3	0.4
Medication: Paracetamol	1.9	3.1	5.6	-2.0	-1.4	-2.1	-1.5	1.2	2.2	-1.2	-1.8	-2.2	-2.4	-2.2	-0.1	-0.7	-2.1
Headache pain in last month	2.7	4.6	7.9	-2.3	-1.7	-2.6	-1.9	-0.8	2.6	-1.1	-2.5	-2.6	-2.8	-2.8	0.1	0.2	-2.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	2.1	-0.8	-0.0	-1.2	0.1	0.2	1.4	0.6	1.4	-0.9	-1.2	-0.8	0.9	-0.6	-1.4
Glaucoma (self-reported)	0.5	0.6	2.9	0.4	1.1	0.2	0.7	1.7	-0.7	-0.2	0.4	1.0	1.0	0.2	0.4	1.1	0.4
Gout (self-reported)	3.2	4.3	9.1	2.5	1.8	2.2	1.5	-1.6	-2.8	1.0	-1.5	3.0	2.2	2.1	0.6	1.9	2.8
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	6.9	0.2	0.1	-0.4	-1.0	1.0	1.5	-1.0	1.1	-1.2	-0.6	-0.8	2.6	0.8	-1.0
Medication: Amlodipine	2.0	2.9	5.3	1.6	1.8	2.3	1.2	-0.8	-2.3	0.9	1.3	2.3	1.5	2.3	1.3	0.9	2.2
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.2	-0.7	-1.0	-0.9	-1.2	0.7	0.9	-0.8	-1.5	-0.9	-0.9	-0.7	-0.9	-0.6	-0.6
Birth weight	1.9	4.1	14.9	1.2	1.6	2.0	2.7	-3.9	-2.3	1.6	1.8	2.3	-0.2	2.6	0.1	-0.4	2.0
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.7	-0.1	0.4	-0.2	-0.3	-1.3	0.3	-0.2	0.2	-0.3	-0.8	-0.5	-0.2	-1.1	-0.4
High blood pressure (siblings)	0.1	0.1	0.3	-0.2	-0.5	0.4	-0.2	-0.5	-0.3	-0.3	0.3	-0.4	0.1	0.2	-0.6	-0.4	-0.0
Forced vital capacity (FVC), Best measure	0.1	0.3	1.1	-0.1	-0.1	-0.1	-0.1	-1.0	0.5	-0.9	0.8	-0.2	-1.0	-0.5	0.3	-0.5	-0.2
Body fat percentage	1.1	4.2	10.8	2.0	-0.2	3.3	1.0	0.0	-2.8	-0.0	1.5	1.6	3.1	3.2	1.2	-0.6	2.9
Leg fat percentage (right)	1.2	4.3	12.0	2.0	-0.1	3.0	1.3	1.4	-2.8	0.7	1.1	1.5	3.4	3.5	0.3	-0.6	2.8
Arm fat-free mass (right)	0.4	2.1	6.8	1.6	-0.4	2.3	-1.1	-2.6	-1.4	-2.1	1.2	0.6	0.1	0.8	0.6	1.1	1.9
Exposure to tobacco smoke outside home	0.4	0.5	1.9	-0.9	-0.7	-0.4	-0.6	1.4	1.0	0.0	-0.3	-0.5	0.3	-1.2	-0.5	-0.4	-0.7
Comparative body size at age 10	0.3	0.8	2.1	0.4	-0.0	0.7	1.1	1.2	-1.1	1.0	-0.2	0.3	0.0	1.5	-1.0	-1.2	0.9
Number of full brothers	0.6	0.7	3.1	0.4	0.5	1.0	0.4	0.1	-0.9	0.8	1.8	1.0	1.3	0.5	0.3	0.1	0.9
Worry too long after embarrassment	0.3	0.5	4.0	-0.3	-0.6	-0.5	1.1	-0.5	-0.1	0.4	-0.3	0.3	-0.2	0.2	-2.0	0.4	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	2.7	0.6	1.3	1.4	1.4	0.3	-1.0	1.6	0.7	1.0	0.9	1.4	0.8	-0.6	1.0
Wheeze or whistling in the chest in last year	0.7	1.3	5.4	-0.7	0.3	-1.1	-0.2	-0.7	1.3	-0.2	-0.5	-1.0	-1.9	-1.1	2.3	-1.0	-1.0
Number of children fathered	0.9	1.0	6.6	-0.6	-0.2	-0.9	-0.5	-1.2	1.0	-1.1	0.1	-0.6	-2.6	-1.1	0.6	-0.6	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.9	-1.2	-1.4	-0.3	-0.1	-0.3	0.4	-1.0	-0.1	-1.1	-0.7	-0.7	-1.2	-0.7	-0.6
Age at first live birth	0.7	1.3	5.9	-0.4	-1.4	-0.8	-0.9	-1.2	-0.1	-0.9	-2.4	-0.4	0.2	0.2	-2.4	-0.4	-0.1
Pulse wave peak to peak time	1.0	1.2	6.7	-0.1	-0.6	-0.2	-2.0	0.2	0.7	-2.6	-0.2	-0.7	-0.8	-1.0	1.1	1.1	-0.5
Health satisfaction	0.4	0.5	4.9	-0.6	0.2	-0.1	0.0	-2.2	0.3	-0.7	-0.2	-0.1	-0.9	0.2	0.4	-0.1	-0.2
Shortness of breath walking on level ground	0.4	0.4	2.5	-0.8	0.9	-0.4	0.7	0.1	0.4	0.5	-0.3	0.4	-0.5	0.4	1.6	-0.8	-0.2
Qualifications: College or University degree	0.2	0.5	2.5	0.9	0.1	0.4	-0.2	0.7	-0.4	-1.2	0.5	0.0	0.6	0.6	-0.3	1.6	0.5
Eye problems/disorders: None of the above	0.5	0.6	4.2	1.1	0.7	0.8	0.1	-2.0	-0.5	0.7	0.4	0.4	0.0	0.4	0.3	0.5	0.7
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.4	0.5	-0.2	1.2	-0.4	-0.2	-0.8	-0.9	-0.1	0.5	0.7	0.8	0.2	-0.7	0.8
Emphysema/chronic bronchitis	0.6	0.7	3.8	-1.0	0.5	-0.6	0.1	-0.5	0.7	0.4	-0.8	-0.4	-0.7	-0.2	1.4	-1.9	-0.8
Medication for pain relief, constipation, heartburn	0.7	1.3	2.6	0.7	1.6	0.9	1.0	-0.4	-1.1	1.0	1.6	1.4	1.1	1.6	1.3	0.1	0.9
Neck or shoulder pain in last month	3.4	4.8	8.8	-2.8	-1.8	-2.7	-1.4	1.0	2.6	-1.2	-3.0	-2.8	-2.4	-2.0	-1.2	-1.2	-2.8
Medication: Blood pressure	0.3	0.6	1.9	0.5	0.1	0.9	0.1	-1.0	-1.1	-0.1	-1.4	0.8	0.3	0.8	-0.7	-0.2	1.0
Angina (self-reported)	0.8	1.1	2.6	-0.2	-1.3	-0.3	-1.3	1.6	0.3	-1.0	-1.5	-0.9	-0.5	-1.3	-1.6	0.0	-0.4
Migraine (self-reported)	5.5	6.9	13.5	-3.0	-2.5	-3.7	-1.8	-0.5	3.2	-1.6	-2.9	-3.0	-3.3	-3.4	-1.6	-0.5	-3.1
Medication: Ibuprofen	0.6	0.7	1.7	-0.7	-1.1	-0.4	0.5	-1.3	0.7	0.1	-1.0	-0.8	-1.3	-0.6	-1.2	-0.8	-0.5
Medication: Allopurinol	5.1	6.7	14.4	3.0	2.1	2.9	1.9	-1.6	-3.8	0.8	-1.1	3.8	2.7	3.1	1.2	2.2	3.5
Medication: Omeprazole	0.4	0.5	1.5	0.2	-0.3	1.0	-0.4	1.2	-0.9	-0.6	-1.2	0.2	0.7	0.3	-0.4	0.5	0.4
Medication: Seretide 50 evohaler	0.6	0.6	3.9	-0.3	0.5	0.4	0.9	2.0	-0.1	0.5	-1.1	0.3	0.5	0.3	-0.4	-1.3	0.1
Mean time to correctly identify matches	1.2	2.2	10.0	-0.5	0.6	0.9	2.0	1.2	-0.6	3.2	1.3	1.0	2.1	0.7	-1.0	-2.3	0.4
Heart disease (mother)	0.4	0.5	2.1	-0.1	0.4	0.4	1.2	1.0	-0.1	1.5	1.3	0.2	0.1	0.4	-0.2	-0.3	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.0	3.3	0.9	1.8	0.1	1.0	1.0	-0.5	1.7	0.9	1.0	-0.3	0.7	1.0	1.2	0.6
Whole body fat mass	0.9	3.8	11.6	2.1	-0.4	3.4	0.3	-0.8	-2.7	-0.9	1.5	1.3	2.4	2.8	1.2	-0.2	2.9
Leg fat mass (right)	0.9	3.5	9.7	2.1	-0.5	3.1	0.4	-0.2	-2.7	-0.5	1.1	1.3	2.4	3.0	0.8	-0.2	2.8
Arm predicted mass (right)	0.4	2.2	8.4	1.5	-0.5	2.2	-1.2	-2.9	-1.3	-2.2	1.2	0.5	-0.1	0.8	0.8	1.2	1.8
Pulse rate, automated reading	0.8	2.6	5.7	-1.9	-2.2	-1.2	-0.5	-2.0	1.6	0.3	-1.0	-1.7	-1.5	-1.1	-1.8	-2.4	-1.6
Alcohol intake frequency.	0.4	0.9	4.6	-0.5	0.2	0.3	1.1	2.1	-0.1	1.1	-1.1	-0.3	-0.5	0.6	0.8	-1.7	-0.2
Comparative height size at age 10	0.3	1.8	10.9	1.1	0.1	0.9	-1.4	-3.3	-0.3	-2.0	1.6	0.1	-0.3	-0.6	0.7	1.4	0.7
Number of full sisters	2.0	2.5	8.3	1.7	2.2	1.2	1.0	-0.4	-1.2	0.6	0.6	2.4	1.8	1.6	2.9	0.3	1.5
Suffer from ‘nerves’	0.9	1.3	2.6	-1.2	-1.3	-1.3	-1.2	-0.0	1.6	-1.4	0.4	-1.5	-0.8	-1.6	0.4	0.5	-1.5
Overall health rating	0.4	0.9	5.7	-1.3	-0.0	-0.5	0.9	-0.1	0.9	1.2	-0.5	-0.5	-0.6	0.1	0.7	-2.4	-0.9
Chest pain or discomfort	2.1	3.0	6.1	-2.1	-0.8	-2.0	0.3	1.8	2.4	1.0	-0.0	-1.6	-2.3	-1.8	0.6	-2.5	-2.2
Had major operations	0.3	0.3	2.1	-0.0	0.1	-0.1	1.4	-0.2	0.2	0.7	-0.1	-0.2	-0.5	0.3	0.3	-1.0	-0.2
Age at last live birth	1.5	2.2	10.2	-1.2	-2.0	-1.4	-0.7	-0.4	0.5	-1.2	-3.2	-0.9	-0.8	-0.3	-2.6	-1.2	-0.7
Family relationship satisfaction	2.3	2.8	6.8	1.4	1.0	2.5	1.8	-1.7	-2.6	0.9	0.6	1.7	1.1	2.3	0.1	-0.1	2.5
Leg pain on walking	0.7	0.9	2.0	-1.3	-0.3	-1.1	-1.2	-0.4	1.4	-0.3	0.3	-1.0	-1.4	-1.2	0.5	0.1	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.7	-0.6	-0.2	-0.4	-0.6	0.0	0.2	-0.6	-0.8	-0.3	-0.8	-0.5	0.3	0.3	-0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.4	2.3	-0.2	-0.5	-0.3	0.1	1.5	-0.1	0.3	0.9	-0.5	-0.4	0.5	-1.1	-0.8	-0.3
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	5.1	2.1	1.2	1.6	0.9	0.3	-1.2	-0.3	1.1	1.4	1.8	1.5	1.1	2.3	1.7
Medication: Aspirin	0.2	0.3	1.2	0.6	-0.7	0.1	-0.7	0.1	0.1	-0.7	-0.8	-0.2	-0.2	-0.4	-1.1	-0.3	0.3
Supplements: Vitamin C	5.0	5.9	11.2	-3.0	-2.1	-3.1	-2.8	1.5	3.0	-1.8	-1.6	-3.3	-2.2	-2.8	-0.9	0.1	-3.0
Knee pain experienced in last month	0.2	0.3	1.3	0.4	-0.1	0.3	0.1	1.1	-0.6	-0.4	0.5	0.5	0.1	0.7	0.8	-0.8	0.5
Hypertension (Self-reported)	0.2	0.5	3.4	-0.0	-0.6	0.3	0.3	-0.4	-0.7	0.9	-0.7	0.3	0.3	0.2	-1.8	-0.6	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.9	0.5	0.4	0.5	0.2	1.4	-0.7	0.4	-1.3	0.5	0.0	0.3	-0.5	0.6	0.4
Illnesses of father: Heart disease	2.6	3.7	8.1	-1.8	-2.0	-1.5	-2.8	1.1	2.5	-2.4	-1.0	-2.4	-2.0	-2.2	1.1	0.5	-1.9
Illnesses of siblings: Diabetes	0.5	0.6	1.2	-0.8	-1.0	-0.7	-0.8	0.1	0.6	-0.4	-1.1	-1.1	-0.4	-1.1	0.6	-0.6	-1.0
Smoking status: Previous	0.7	1.1	3.0	-1.7	-0.8	-1.4	-0.5	-0.5	0.8	-0.5	-0.8	-1.0	-0.8	-0.9	-1.3	-1.0	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	3.8	1.4	1.3	1.8	1.0	-2.0	-1.5	0.2	0.8	1.4	0.6	1.3	0.8	-0.1	1.5
Whole body fat-free mass	0.4	2.5	6.7	1.6	-0.5	2.5	-1.4	-2.6	-1.5	-2.5	1.2	0.5	0.1	0.9	0.9	1.1	2.0
Leg fat-free mass (right)	0.6	3.3	8.8	1.9	0.0	3.0	-1.0	-2.8	-2.0	-2.3	1.1	1.2	0.4	1.4	1.9	1.2	2.5
Arm fat percentage (left)	1.1	4.4	11.6	2.0	0.1	3.3	1.1	0.2	-2.9	0.1	1.4	1.5	2.9	3.4	1.7	-0.9	2.9
Average weekly red wine intake	3.2	4.7	8.3	-2.2	-2.4	-2.6	-1.9	1.4	2.8	-1.5	-0.9	-2.2	-2.1	-2.9	-2.3	-1.2	-2.6
Handedness (chirality/laterality): Left-handed	4.3	5.2	10.8	-2.6	-1.9	-3.3	-1.9	0.8	3.1	-1.6	-2.2	-2.3	-2.4	-2.9	-1.7	-0.7	-2.8
Mood swings	0.3	0.6	3.3	-0.5	-0.8	-0.6	0.5	-1.5	0.3	0.8	-1.8	-0.5	-0.5	-0.0	-0.4	-0.2	-0.3
Loneliness, isolation	1.5	2.0	7.7	2.0	0.6	1.6	-0.2	0.5	-1.9	-0.1	-0.7	1.3	1.4	1.4	0.1	2.8	1.7
Long-standing illness, disability or infirmity	1.2	1.9	3.5	-1.9	-1.2	-1.4	0.4	0.9	1.6	0.7	-1.8	-1.2	-1.5	-0.9	-1.5	-1.9	-1.4
Ever had bowel cancer screening	0.2	0.3	1.1	0.1	0.3	-0.2	-0.7	0.6	0.0	-0.7	0.4	-0.1	-0.1	-0.8	0.5	1.1	-0.4
Diabetes diagnosed by doctor	0.8	1.3	4.3	-1.1	-2.1	-0.4	-1.3	1.1	0.6	-1.2	-1.4	-1.4	0.0	-0.4	-1.5	-1.0	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.0	-0.4	0.6	-0.5	1.0	0.8	0.3	-0.0	-0.7	-0.1	-0.6	0.5	1.0	-1.4	-0.6
Friendships satisfaction	0.6	0.8	2.8	0.6	-0.5	1.0	-1.0	-1.3	-0.7	-1.7	0.4	0.3	0.1	0.3	0.0	1.5	1.0
Qualifications: nursing, teaching	2.4	3.7	6.5	-2.2	-1.6	-2.6	-1.7	1.6	2.4	-1.1	-0.6	-2.1	-2.4	-2.4	-1.7	-1.4	-2.3
Commuting to job workplace: Walk	0.5	0.6	1.5	1.1	0.9	0.7	0.0	0.3	-0.3	0.1	-0.7	0.9	0.6	0.7	1.0	1.2	0.9
Eye problems/disorders: Cataract	1.0	1.2	2.7	-1.2	-1.1	-1.2	-1.4	0.3	1.2	-1.6	-1.4	-0.9	-0.7	-1.3	-0.4	0.4	-1.1
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	12.5	0.4	2.1	1.1	0.6	0.1	-0.4	0.9	1.6	0.7	-0.5	1.5	3.5	-0.0	0.2
Medication for cholesterol	0.2	0.4	1.3	-0.6	0.2	-0.7	0.2	0.7	0.9	-0.3	0.3	-0.1	-1.1	-0.5	0.6	0.6	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.9	-0.3	0.1	-0.2	-0.3	0.8	0.1	-0.2	0.0	-0.2	0.8	-0.8	-0.9	0.0	-0.3
Back pain experienced in last month	0.7	1.0	3.1	0.4	1.6	0.6	1.8	-0.2	-0.6	1.2	0.3	1.4	-0.3	1.5	0.8	-1.0	0.7
Mineral and other dietary supplements	0.7	0.9	2.6	0.4	0.4	0.4	1.4	-1.3	-0.5	1.4	-1.2	0.5	-0.2	1.1	-1.1	-1.6	0.3
Breast cancer (self-reported)	0.4	0.5	1.6	0.6	1.1	0.7	0.4	-0.2	-0.3	0.3	0.9	1.1	0.5	0.3	1.3	0.2	0.7
Asthma (self-reported)	0.6	1.1	7.2	0.3	1.6	0.1	-0.3	1.7	0.1	-0.4	-0.8	0.6	0.3	-0.0	2.7	1.3	0.5
Osteoporosis (self-reported)	1.0	1.3	3.0	0.7	1.0	1.1	1.7	0.7	-1.3	1.3	1.0	0.8	1.4	1.7	0.8	1.0	0.7
Osteoarthritis (self-reported)	0.6	0.8	2.4	0.6	0.1	0.9	0.5	0.8	-0.8	-0.5	-0.6	0.7	1.1	1.2	1.1	1.6	0.9
Medication: Aspirin	0.5	0.6	1.7	-0.1	-1.0	-0.5	-0.9	0.4	0.7	-0.7	-1.0	-0.8	-0.6	-0.8	-1.3	-0.9	-0.4
Medication: Gliclazide	1.3	1.4	6.6	0.6	-0.6	0.6	-1.2	2.3	-0.5	-2.6	-0.3	-0.1	0.7	0.7	0.4	1.9	0.6
Illnesses of father: None of the above (group 1)	3.1	3.9	6.9	1.7	2.1	2.0	2.5	-0.8	-2.6	2.5	1.4	2.5	2.2	2.3	-0.6	-0.2	2.1
Smoking status: Current	1.1	1.8	8.2	-0.8	0.1	-0.5	1.1	-2.0	0.8	2.6	1.2	-0.3	-0.9	-0.5	-0.7	-2.9	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	2.3	0.5	0.7	0.3	0.7	0.3	-0.9	0.3	-0.2	0.6	0.2	0.2	-1.5	-1.0	0.3
Whole body water mass	0.4	2.1	6.3	1.4	-0.6	2.3	-1.5	-2.5	-1.3	-2.5	1.1	0.3	-0.1	0.8	0.8	0.8	1.8
Leg predicted mass (right)	0.7	3.5	9.4	1.9	0.1	3.1	-0.9	-2.8	-2.1	-2.3	1.2	1.3	0.5	1.5	1.9	1.2	2.6
Arm fat mass (left)	0.9	3.6	11.3	1.9	-0.4	3.4	0.2	-0.5	-2.7	-0.8	1.6	1.1	2.2	2.9	1.5	-0.6	2.8
Number of self-reported non-cancer illnesses	0.5	0.9	2.1	-0.9	-1.4	-1.1	-0.3	1.4	1.1	0.2	-1.2	-1.1	-0.6	-0.8	-0.8	0.1	-0.9
Average weekly champagne plus white wine intake	0.5	0.6	2.7	0.3	-0.8	-0.3	-0.8	1.0	-0.2	-0.7	-0.6	-0.0	1.7	-0.1	-0.4	1.6	0.2
Miserableness	1.0	1.7	5.9	1.6	1.3	1.5	1.4	0.1	-1.3	0.5	-0.1	1.5	0.4	2.4	1.6	0.9	1.4
Guilty feelings	0.4	0.6	1.6	0.6	0.8	0.8	0.6	-0.5	-0.8	0.1	-0.9	0.8	0.2	1.0	1.3	0.9	0.8
Wears glasses or contact lenses	0.4	0.5	2.2	0.5	0.1	0.4	0.1	-0.4	-0.6	0.7	0.4	0.5	1.3	0.3	0.7	1.5	0.4
Ever taken oral contraceptive pill	0.6	0.7	3.2	1.0	0.2	0.3	-0.5	0.9	-0.7	-0.8	-0.4	0.4	1.3	0.6	-0.1	1.8	0.6
Hearing aid user	1.5	1.7	4.0	1.2	1.7	1.4	0.8	2.0	-1.4	0.1	1.6	1.5	1.2	0.9	1.1	1.0	1.3
Mother’s age at death	0.4	0.5	1.7	0.3	1.2	0.1	1.2	-0.4	-0.2	1.3	1.2	0.9	-0.2	0.0	-0.3	-0.7	0.2
Financial situation satisfaction	0.5	0.6	2.3	-0.6	0.2	-0.2	0.4	-1.4	0.4	0.4	-0.9	-0.0	-0.8	-0.0	1.1	-1.5	-0.2
Tinnitus: Yes, now most or all of the time	0.9	1.0	2.9	-1.2	0.0	-1.1	1.0	-1.5	0.4	1.4	0.1	-0.2	-1.7	-0.2	0.2	-1.5	-1.0
Commuting to job workplace: Public transport	0.6	0.7	9.0	-0.3	-0.2	-0.2	0.3	-3.0	0.1	0.1	0.2	-0.1	0.1	-0.5	-0.8	0.4	0.1
Eye problems/disorders: Glaucoma	0.8	0.9	3.1	0.8	1.1	0.8	0.6	1.8	-1.3	-0.5	-0.3	1.2	1.0	0.8	0.6	0.9	0.9
Medication: Blood pressure	0.2	0.4	2.1	-0.4	-0.7	-0.1	0.5	-0.2	-0.5	0.9	-0.5	0.1	0.1	0.2	-1.4	-0.7	0.2
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.3	-1.1	-0.9	-1.0	-1.4	0.1	1.1	-1.5	-0.2	-0.8	-1.4	-1.1	0.8	0.8	-1.2
Supplements: Fish oil (including cod liver oil)	1.1	1.5	3.2	-1.4	-1.3	-1.2	-1.4	1.6	1.4	-1.5	0.4	-1.4	-0.5	-1.8	-0.1	0.5	-1.1
High cholesterol (Self-reported)	0.6	1.0	7.8	-0.9	-1.2	-0.2	-0.7	2.8	0.2	0.2	-0.6	-0.8	0.7	-0.6	-1.3	-0.5	-0.2
Medication: Bendroflumethiazide	1.4	2.1	12.3	-1.6	-1.8	-1.2	-0.9	-0.4	0.8	-0.5	-3.5	-1.1	-0.7	-0.9	-1.7	-1.4	-1.0
Medication: Paracetamol	1.9	3.0	6.2	-1.8	-1.2	-2.2	-1.7	0.9	2.1	-1.3	-1.7	-2.0	-2.2	-2.5	0.2	-0.3	-2.1
Medication: Lisinopril	1.9	2.4	6.0	-2.2	-2.0	-1.5	-0.6	0.9	1.3	-0.9	-1.5	-1.4	-2.4	-1.6	-1.6	-1.1	-1.6
Medication: Atorvastatin	2.5	3.1	8.0	1.7	1.0	2.3	1.6	0.7	-2.2	2.1	0.4	2.1	2.8	2.0	-0.8	0.3	2.2
Illnesses of father: High blood pressure	0.7	0.8	4.2	-0.1	-0.9	-0.2	-0.5	1.6	0.1	-1.6	-2.1	-0.1	-0.1	-0.4	-0.4	0.8	-0.0
Alcohol drinker status: Never	1.6	1.9	5.0	0.8	1.7	1.3	2.2	0.3	-1.2	2.1	0.0	1.7	0.8	1.8	1.5	-0.2	1.2
Ever smoked	1.2	2.0	6.6	-1.7	0.1	-1.1	1.9	-1.3	1.1	2.4	1.4	-0.3	-1.0	-0.5	-1.1	-2.6	-1.1
Basal metabolic rate	0.5	2.8	7.7	1.8	-0.5	2.8	-1.2	-2.3	-1.8	-2.4	1.4	0.7	0.5	1.3	1.1	1.0	2.3
Leg fat percentage (left)	1.1	4.1	11.0	2.1	0.1	2.9	1.3	0.9	-2.8	0.6	1.0	1.7	3.3	3.3	0.6	-0.5	2.8
Arm fat-free mass (left)	0.4	1.8	5.6	1.2	-0.9	2.1	-1.4	-1.9	-1.1	-2.4	1.0	0.1	0.0	0.8	0.8	0.8	1.6
Number of operations (self-reported)	0.3	0.5	1.6	0.6	0.6	0.6	1.3	1.1	-0.7	0.7	0.6	0.6	0.6	0.3	0.2	-0.3	0.8
Average weekly beer plus cider intake	0.9	1.3	2.6	-1.5	-1.3	-1.4	-0.3	0.5	1.6	0.0	-0.2	-1.0	-1.0	-1.4	-0.8	-1.5	-1.3
Irritability	0.3	0.5	3.3	0.2	-0.2	-0.0	0.3	-1.3	-0.3	-0.1	-1.8	0.0	-0.7	0.4	0.2	1.0	0.2
Risk taking	0.2	0.3	1.6	0.1	0.4	0.4	0.0	1.2	-0.1	0.2	0.3	0.4	1.3	0.3	0.1	-0.4	0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.6	0.8	0.8	0.6	0.0	0.7	-0.8	-0.6	-0.5	0.5	-0.2	-0.4	-0.4	0.5	0.7
Fractured/broken bones in last 5 years	4.4	5.7	15.8	3.0	2.1	2.9	1.4	-0.6	-2.8	1.2	0.7	2.3	4.0	2.5	1.4	2.6	2.9
Age started oral contraceptive pill	1.5	1.8	3.9	1.4	0.4	1.1	1.6	-2.0	-1.4	2.0	1.2	1.3	1.1	1.2	-1.6	-0.2	1.3
Diastolic blood pressure, automated reading	1.4	4.5	13.0	2.4	0.7	3.2	0.8	-0.5	-3.1	0.5	1.0	2.2	3.6	2.4	0.6	1.2	3.0
Ever depressed for a whole week	1.5	1.9	4.1	-1.6	-0.6	-1.8	-1.4	0.1	2.0	-0.9	-0.4	-1.8	-1.1	-1.9	0.8	0.0	-2.0
Unable to work because of sickness or disability	0.4	0.5	1.9	-0.4	0.5	0.1	1.4	0.9	-0.1	0.7	-0.2	0.4	-0.1	0.8	1.0	-1.2	0.0
Commuting to job workplace: Cycle	0.5	0.6	3.2	0.8	0.9	0.4	0.6	-1.8	-0.8	0.1	0.3	1.0	0.2	0.4	-0.0	0.4	0.7
Myopia	0.2	0.3	1.7	-0.1	-0.7	-0.1	0.0	0.6	-0.3	-0.2	0.9	-0.2	0.5	-0.5	-1.3	0.9	0.2
Vascular/heart problems diagnosed by doctor	0.2	0.6	4.0	-0.4	0.9	-0.6	0.1	-0.3	0.9	-0.2	1.1	-0.5	-0.6	-0.1	2.0	0.1	-0.9
Cholesterol lowering medication	0.2	0.3	1.7	-0.0	-0.7	0.4	-0.2	1.3	-0.5	0.6	0.0	0.1	0.8	0.3	-0.7	0.0	0.3
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.9	-0.4	-1.0	0.3	-0.8	1.2	-0.3	-1.2	-1.7	-0.7	-0.4	-0.2	-0.7	0.4	-0.2
Pain experienced in last month	1.0	1.7	4.1	1.4	1.2	1.7	1.1	-0.3	-1.5	1.6	1.1	1.3	2.0	1.2	-0.5	-0.2	1.6
Supplements: Calcium	0.7	0.8	2.4	0.7	1.3	1.1	0.4	0.1	-0.8	-0.2	1.6	0.7	1.0	0.4	1.1	0.9	0.7
Basal cell carcinoma (self-reported)	1.1	1.3	2.9	1.4	0.4	1.3	0.4	-1.7	-1.7	0.4	-0.6	1.3	0.6	1.0	-1.1	1.2	1.3
Heart attack/myocardial infarction (self-reported)	1.9	2.5	5.0	-1.2	-2.1	-1.7	-0.8	2.2	1.4	-1.0	-2.0	-1.8	-1.4	-1.0	-2.2	-0.7	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.1	0.2	-0.3	0.4	-0.9	-1.1	-0.3	-0.7	-0.5	-0.1	-0.0	0.3	0.3	0.5	0.4
Heart disease (siblings)	0.6	0.8	2.3	-0.8	-1.5	-0.6	-1.1	0.3	0.7	-1.0	-1.2	-0.8	-0.4	-1.0	-0.7	0.1	-0.8
Alcohol drinker status: Previous	0.7	0.8	1.6	-1.1	-0.5	-0.9	-0.0	0.8	1.3	0.6	-0.3	-1.1	-0.9	-0.9	0.1	-1.2	-1.0
Pack years of smoking	0.1	0.2	0.7	-0.4	-0.4	0.2	-0.4	-0.8	0.3	-0.7	0.5	-0.5	-0.7	-0.4	0.1	-0.3	-0.2
Impedance of whole body	0.1	0.7	1.8	-1.1	0.3	-1.3	0.8	-0.1	1.3	0.9	0.2	-0.3	-0.2	-1.0	-0.3	-0.8	-1.3
Leg fat mass (left)	0.9	3.4	9.3	2.1	-0.4	3.1	0.3	-0.4	-2.7	-0.7	1.0	1.3	2.3	2.9	0.9	-0.1	2.8
Arm predicted mass (left)	0.4	1.9	6.5	1.2	-1.1	2.1	-1.5	-2.0	-1.2	-2.5	1.0	0.0	-0.1	0.7	0.4	1.0	1.6