Hub : Genes

TMEM120A

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adrenal Gland 0.1150 0.0544 4.9e-03 -0.007 NA -0.008 NA -0.004 7.2e-01 NA 7.9e-01 NA 5.0e-01
2 GTEx Cells Transformed fibroblasts 0.2400 0.0540 3.8e-08 0.014 NA 0.051 NA 0.072 2.9e-02 NA 9.9e-05 NA 4.3e-06
3 GTEx Esophagus Mucosa 0.0730 0.0330 2.7e-03 0.006 NA 0.017 NA 0.014 1.3e-01 NA 2.6e-02 NA 3.5e-02
4 GTEx Nerve Tibial 0.1062 0.0359 1.8e-04 0.082 NA 0.069 NA 0.077 2.1e-06 NA 1.2e-05 NA 4.3e-06
5 GTEx Thyroid 0.0760 0.0360 6.8e-03 0.015 NA 0.019 NA 0.012 2.5e-02 NA 1.3e-02 NA 4.1e-02
6 GTEx Whole Blood 0.0460 0.0230 6.3e-03 0.024 NA 0.013 NA 0.015 2.4e-03 NA 2.2e-02 NA 1.3e-02
7 ROSMAP Brain Pre-frontal Cortex 0.0496 0.0195 1.0e-04 0.013 0.019 0.002 0.019 0.009 6.6e-03 0.0015 1.8e-01 0.0014 1.9e-02
8 TCGA Thyroid Carcinoma 0.0370 0.0250 7.9e-03 -0.002 0.019 0.011 NA 0.001 6.8e-01 0.0056 2.7e-02 NA 2.5e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.6 2.6 5.0 1.3 -1.2 -1.9 -1.9 0.0 1.5 2.2 -1.8
Bipolar Disorder or Schizophrenia 0.3 0.7 1.5 0.5 -0.5 -0.2 -0.8 -1.0 0.7 1.2 -0.9
Depressed Affect (Nagel 2018) 3.1 6.5 15.9 2.7 -0.6 -4.0 -0.7 -3.4 1.0 3.6 -1.4
Depression (Nagel 2018) 3.6 5.4 15.4 2.9 -1.3 -3.9 -1.6 -2.4 0.9 2.8 -0.8
Intelligence (Savage-Jansen 2018) 1.0 3.0 5.9 -2.4 1.6 0.9 1.9 1.6 -1.5 0.9 2.3
Neuroticism (Nagel 2018) 2.6 6.2 12.6 3.2 0.2 -3.5 0.2 -3.4 1.7 3.1 -1.5
Schizophrenia (2018) 0.3 0.6 2.2 -0.7 0.4 1.2 0.5 1.5 -0.2 -0.0 0.1
Schizophrenia vs Biploar Disorder 0.3 0.4 1.6 -0.8 0.2 1.3 0.5 0.0 0.1 -0.3 -0.9
Worry (Nagel 2018) 1.4 2.9 7.4 2.2 -0.4 -2.3 -0.7 -2.7 1.6 1.2 -1.3
Alzheimer’s Disease (in mother) 1.2 1.4 3.5 1.6 -0.5 -1.5 -0.6 -1.9 -0.2 1.5 -0.1
Alzheimer’s Disease (in father) 0.9 0.9 1.9 -0.3 1.3 -0.2 1.4 1.3 -1.2 -0.4 0.8
Alzheimer’s Disease (including proxy) 0.7 1.0 4.2 1.0 0.1 -2.1 0.1 -1.0 -0.7 1.1 0.2
Crohns Disease (2017) 1.4 3.2 12.6 0.9 3.5 -0.1 2.5 2.1 -0.8 0.7 0.4
Irritable Bowel Disease (IBD) 1.2 3.0 7.3 -1.0 2.7 1.1 2.1 1.8 -1.5 -1.2 1.7
Ulcerative Colitis (UC) 1.4 2.7 4.6 -2.1 1.4 1.5 1.2 0.9 -1.5 -2.1 1.9
Major Depression (MDD) 2.2 2.7 11.6 1.2 -0.3 1.3 -0.2 -0.5 3.4 -0.1 -2.6
Reaction Time 2.6 4.9 15.1 0.8 -3.5 -1.6 -3.9 -2.8 0.2 0.8 -0.4
Verbal and Numeric Reasoning (VNR) 1.5 3.6 7.6 -2.2 1.4 1.6 2.0 2.2 -1.7 -0.5 2.8
Breast Cancer 0.3 0.8 4.2 -2.1 -0.1 1.2 -0.3 0.6 0.5 -0.4 -0.4
Ovarian Cancer 2.1 2.8 8.6 -2.2 0.0 0.8 0.0 0.6 -1.9 -2.1 2.9
Prostate Cancer 0.7 0.9 3.5 -0.7 1.1 1.9 0.9 0.6 -0.1 -0.9 -0.1
Age at First Birth 0.1 0.2 0.8 -0.3 -0.3 0.9 0.0 -0.2 0.5 -0.3 -0.5
Bipolar Disorder (2011) 0.3 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -1.6
Body Mass Index (BMI) (2010) 1.0 1.3 4.6 -1.0 -1.0 0.8 -1.2 -0.8 -0.7 -2.1 0.8
Coronary Artery Disease (CAD) 0.6 0.7 3.2 -0.0 -1.3 -0.6 -1.8 0.0 0.1 -0.5 0.1
Crohns Disease (2012) 0.0 0.1 0.4 -0.2 0.6 -0.2 0.0 0.0 -0.1 0.4 -0.0
Mean Putamen Volume 2.4 2.7 8.3 -1.6 1.3 2.5 1.3 0.7 0.8 -2.9 -0.3
Fasting Glucose 1.2 1.5 4.4 0.7 0.6 1.9 0.0 -0.3 1.4 -1.0 -2.1
HbA1C 0.8 0.8 3.0 -0.0 -0.5 -0.7 -0.3 -1.7 -1.4 0.9 -0.4
HDL Cholesterol 0.9 1.4 3.4 0.5 -1.8 -1.6 -1.4 -0.6 0.8 1.2 -0.9
LDL Cholesterol 2.7 4.3 6.5 -1.9 2.4 2.3 2.5 2.0 -1.4 -2.1 1.6
Lupus 0.2 0.3 0.7 -0.7 0.5 0.8 0.5 -0.0 0.8 0.1 -0.4
Neuroticism (2016) 1.2 1.7 3.7 1.8 0.3 -1.7 0.7 0.0 1.6 1.9 -0.6
Primary Biliary Cirrhosis 0.3 0.4 0.9 0.1 -0.4 -0.9 -0.9 -0.5 -0.5 -0.7 0.8
Rheumatoid Arthritis 2.1 2.9 6.0 -2.5 0.2 1.4 -0.0 2.0 -1.6 -2.0 2.1
Schizophrenia (2014) 0.1 0.3 0.7 -0.4 0.4 0.7 0.5 0.8 -0.3 -0.5 0.4
Triglycerides 1.4 2.3 4.2 -1.0 0.9 2.0 1.1 1.7 -1.7 -1.5 1.8
Type 2 Diabetes (T2D) (2012) 1.2 1.3 4.5 0.3 -2.1 0.7 -1.8 0.0 1.3 -0.8 -0.4
Ulcerative Colitis 1.1 1.6 4.3 -2.1 -0.0 1.0 -0.3 0.0 -1.0 -2.1 1.5
Blood Eosinophil Count 3.1 24.0 84.5 6.5 -1.5 -9.2 0.7 -4.1 -0.1 6.8 0.9
Blood Platelet Count 1.8 20.9 48.7 -7.0 1.3 5.0 1.2 5.3 -4.1 -5.1 4.4
Blood Red Count 0.1 1.3 3.1 -0.8 -1.4 0.9 -1.8 -0.4 1.0 -1.3 -0.9
Blood White Count 0.8 6.1 12.7 1.1 -3.1 -2.3 -2.8 -3.6 1.0 2.3 -2.4
Heel T-Score 0.4 3.3 13.7 -0.3 -3.2 -0.3 -3.7 -0.7 0.4 -1.4 0.3
BMI 1.2 6.8 14.1 -2.6 -0.8 2.9 -0.2 2.9 -2.3 -3.2 3.8
Height 0.1 1.3 4.2 2.0 -0.1 -2.0 0.6 -0.2 0.8 0.7 -0.7
Waist Hip Ratio (WHR) 0.7 3.2 10.9 1.7 1.1 -1.9 1.1 -0.8 1.2 3.3 -1.9
Systolic Blood Pressure 0.1 0.3 1.5 -0.1 0.4 -0.1 0.5 -1.2 0.4 -0.6 -0.5
Smoking Status 0.8 1.9 5.6 1.6 0.9 -1.3 1.0 -0.4 2.4 1.5 -1.0
Allergy or Eczema 0.7 1.8 3.5 1.0 1.0 -1.7 1.9 0.7 -1.2 1.6 1.1
Cardiovascular Disease 1.5 5.1 14.2 -2.2 1.6 3.8 1.7 1.9 -0.9 -3.2 1.1
Hypothyroidism (self reported) 0.4 1.0 3.3 0.6 0.1 0.1 -0.7 -1.2 1.8 0.7 -1.4
Respiratory disease 0.6 1.3 4.2 0.9 0.1 1.0 -0.3 -0.3 2.1 -0.9 -1.8
Type 2 Diabetes (T2D) (2018) 0.8 1.5 3.5 -1.5 -1.0 1.9 -0.6 0.3 -0.3 -1.8 1.2
Lung FEV1/FVC ratio 0.9 4.6 10.9 -0.3 1.0 -2.2 1.5 1.1 -2.7 3.0 3.3
Lung FVC 0.6 2.9 9.1 0.3 -3.0 1.0 -2.6 -1.1 1.1 -1.0 -1.8
Neuroticism 2.8 6.8 13.3 3.6 1.2 -3.1 1.1 -2.4 2.5 3.6 -2.0
Chronotype (morning person) 1.8 4.2 12.9 1.9 -3.6 -1.6 -2.5 -2.5 0.6 0.8 -0.9
Hair Pigment 0.1 1.4 3.1 0.4 -0.6 1.7 -0.4 -1.8 1.2 -1.0 -1.5
Tanning 0.2 2.0 6.8 0.5 -0.9 -0.4 -2.0 -1.0 1.7 0.5 -2.6
Hand grip strength (left) 0.8 2.2 7.1 0.9 -0.2 -1.3 -0.4 -0.7 2.7 1.6 -2.1
Number of treatments/medications taken 0.7 1.2 2.1 -1.2 0.6 0.2 0.8 1.3 -1.3 -1.4 1.2
Average weekly spirits intake 0.4 0.5 1.2 -0.8 0.4 1.1 0.6 0.2 0.7 -0.7 -0.6
Sensitivity / hurt feelings 1.4 2.4 5.6 1.3 1.0 -0.8 1.4 -2.1 2.4 1.3 -1.5
Frequency of depressed mood in last 2 weeks 1.7 2.3 8.0 2.1 -0.3 -2.8 -0.6 -0.9 1.2 1.9 -0.3
Hearing difficulty/problems: Yes 0.6 0.9 4.3 0.1 -0.1 -2.1 0.4 -1.1 -0.2 0.9 0.6
Relative age of first facial hair 0.8 1.6 5.3 1.4 0.5 -2.3 1.0 -0.9 -0.1 1.8 0.0
Other serious medical condition/disability diagnosed by doctor 0.6 0.8 3.0 -0.9 0.7 0.3 0.2 1.7 -0.5 -1.0 1.0
Ever used hormone-replacement therapy (HRT) 1.5 1.9 4.4 -1.7 0.8 1.0 1.2 1.2 -2.1 -0.7 1.6
Ever had hysterectomy (womb removed) 0.3 0.3 0.9 -0.2 0.5 0.9 0.5 1.0 -0.3 -0.4 0.1
Systolic blood pressure, automated reading 0.2 0.5 1.8 -0.4 0.5 0.6 0.4 0.1 -0.4 -1.3 0.9
Eye problems/disorders: Diabetes related eye disease 0.5 0.5 1.9 0.7 -0.8 -0.7 -0.1 -0.6 0.4 1.4 -0.2
Angina 0.5 0.7 3.4 0.2 -0.2 -1.0 -0.3 0.1 -1.8 0.4 0.7
Medication for hormone replacement therapy 0.7 0.8 1.6 -1.1 -1.3 0.2 -1.0 -0.8 -1.1 -0.0 0.3
Vitamin and mineral supplements 0.6 0.8 1.9 -0.4 1.2 0.6 1.4 0.8 -1.2 0.3 0.1
Supplements: Zinc 0.3 0.3 1.2 0.4 -0.6 -0.3 -1.1 -0.5 0.3 -0.1 0.1
Medication: Co-codamol 0.4 0.5 2.2 -0.4 -0.7 -0.1 -1.5 -0.6 -0.1 -0.6 -0.2
Medication: Metformin 1.7 2.5 6.6 -1.9 -1.3 1.5 -0.5 0.3 -1.2 -2.6 1.9
Diabetes (father) 0.3 0.4 1.6 -0.6 0.3 -1.2 -0.1 0.1 -0.3 -0.8 0.7
Diabetes (mother) 1.9 2.4 6.5 -2.0 -0.4 1.7 0.3 -0.1 -1.5 -2.5 1.7
Severe depression (siblings) 2.8 3.2 6.3 2.1 -0.9 -1.1 -1.9 -1.5 2.1 1.4 -2.5
Pack years adult smoking proportion 0.5 0.7 1.3 -0.4 -1.0 -0.1 -1.1 -1.1 0.7 -1.1 -0.4
Impedance of leg (right) 1.6 7.8 15.1 2.8 -1.4 -2.6 -1.6 -3.9 2.5 3.2 -3.4
Leg fat-free mass (left) 0.4 2.3 5.9 -1.0 0.1 2.0 0.3 2.4 -0.7 -2.1 1.5
Trunk fat percentage 0.6 2.4 4.6 -1.4 -1.3 0.8 -0.7 1.6 -1.5 -2.1 2.2
Hand grip strength (right) 1.0 2.8 4.1 0.8 -2.0 -1.8 -1.8 -1.5 1.9 1.6 -1.7
Townsend deprivation index at recruitment 2.7 3.7 11.2 3.3 0.0 -2.3 -0.1 -2.4 1.8 1.3 -1.6
Current tobacco smoking 0.7 1.1 3.2 1.0 0.7 -0.8 0.8 -0.3 1.8 1.6 -0.5
Average weekly fortified wine intake 3.7 4.4 11.2 -3.3 1.4 2.3 1.3 2.1 -0.9 -2.4 1.9
Maternal smoking around birth 2.0 2.9 8.4 1.4 -1.6 -2.9 -1.3 -1.8 -0.1 2.2 -0.6
Fed-up feelings 1.7 3.0 9.0 2.4 0.2 -2.8 -0.1 -1.0 0.5 3.0 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 1.9 2.5 5.8 2.4 -0.8 -2.4 -0.8 -1.3 1.1 2.0 -0.7
Relative age voice broke 1.9 2.9 7.1 -1.2 2.7 0.6 2.6 1.1 -2.0 -0.7 1.4
Taking other prescription medications 0.4 0.6 1.7 -0.6 1.2 0.5 0.6 0.7 0.0 -1.3 0.2
Age when periods started (menarche) 0.4 1.1 4.0 -0.1 2.0 0.4 1.8 0.7 -0.0 0.3 -0.7
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 1.9 -0.6 0.5 1.4 -0.2 0.5 -0.5 -0.1 0.0
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 1.2 -0.6 0.4 -1.1 -0.5 0.8 -1.0 -0.7 0.4
Tinnitus: Yes, but not now, but have in the past 3.7 3.9 7.0 2.3 -2.6 -2.2 -2.5 -1.9 1.7 0.5 -1.2
Qualifications: CSEs or equivalent 1.4 1.9 5.8 -0.4 2.4 0.2 2.2 0.9 0.9 1.4 -0.9
Serious illness, injury or assault to yourself 0.9 1.1 5.0 -0.9 0.6 2.2 -0.2 0.9 0.7 -1.2 -0.4
High blood pressure 1.6 4.5 12.9 -1.6 1.9 3.6 1.2 2.0 -0.7 -3.3 0.8
Hayfever, allergic rhinitis or eczema 0.7 1.6 3.6 0.9 1.1 -1.3 1.8 0.1 -1.3 1.9 0.6
Multivitamins +/- minerals 0.5 0.6 1.8 -0.4 -0.7 -0.7 -1.3 -0.7 1.1 -0.6 0.0
Stomach or abdominal pain in last month 0.3 0.3 0.9 -0.9 -0.2 0.3 0.6 -0.3 -0.4 0.1 1.0
Supplements: Glucosamine 3.0 3.9 9.9 -2.8 0.7 2.9 0.6 1.5 -0.6 -3.1 1.0
Diverticular disease/diverticulitis (self-reported) 0.8 1.0 2.3 -0.6 -0.9 -1.4 -0.9 -0.9 -0.7 -0.2 1.5
Medication: Atenolol 1.6 2.0 5.8 -1.7 0.1 1.0 -0.1 1.3 -2.4 -1.3 1.6
Medication: Levothyroxine sodium 0.2 0.4 1.0 0.8 0.1 -0.6 -1.0 -0.5 0.0 0.5 -0.8
Sitting height 0.4 2.8 7.6 2.1 1.7 1.2 1.5 0.6 1.7 0.4 -2.8
Chronic bronchitis/emphysema (father) 0.4 0.4 1.2 -0.3 -1.0 -0.2 -0.8 -0.5 -0.4 -1.1 -0.4
High blood pressure (mother) 1.3 1.9 4.2 -1.5 -0.5 2.1 0.2 0.4 -1.5 -1.9 1.4
Body mass index (BMI) 1.0 4.1 7.9 -2.3 -0.7 2.0 -0.5 2.2 -1.8 -2.6 2.8
Impedance of leg (left) 1.3 6.5 10.5 2.6 -1.3 -2.8 -1.5 -3.2 2.1 3.2 -2.9
Leg predicted mass (left) 0.4 2.3 6.0 -0.9 0.0 1.9 0.2 2.5 -0.8 -2.1 1.6
Trunk fat mass 0.7 2.8 5.9 -1.4 -0.9 1.3 -0.4 2.2 -1.5 -2.4 2.2
Waist circumference 0.5 1.7 5.0 -1.0 -0.1 1.2 0.2 2.2 -1.1 -1.6 1.6
Number of incorrect matches in round 0.3 0.5 1.0 -0.3 0.7 -0.2 1.0 1.0 -0.1 -1.0 0.7
Past tobacco smoking 0.3 0.6 1.7 -0.9 -0.6 0.9 -0.7 -0.5 -1.3 -0.2 0.6
Alcohol usually taken with meals 3.3 5.4 8.6 -2.7 0.8 2.8 1.0 2.6 -2.4 -2.9 2.2
Nervous feelings 0.6 1.1 2.5 1.2 -0.0 -0.8 -0.2 -1.2 1.6 0.8 -1.3
Frequency of tenseness / restlessness in last 2 weeks 1.4 2.1 6.9 1.6 -1.3 -2.6 -1.1 -1.6 0.4 1.3 0.1
Hearing difficulty/problems with background noise 0.4 0.7 3.4 -0.4 -0.1 -1.9 -0.1 -1.2 0.2 0.7 0.2
Hair/balding pattern: Pattern 2 0.2 0.2 0.7 -0.4 0.2 0.2 0.2 -0.3 0.2 0.8 -0.9
Had menopause 0.1 0.2 0.5 0.3 0.5 -0.1 0.2 -0.4 0.3 0.7 -0.3
Had other major operations 3.1 3.8 12.0 2.0 3.5 1.3 2.9 1.5 1.0 0.7 -0.7
Forced vital capacity (FVC) 0.6 2.3 7.5 1.6 -0.8 0.6 -0.8 -0.5 2.3 1.2 -2.7
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 3.5 -1.7 -0.6 -0.4 -1.2 0.7 -1.0 -1.9 1.0
Ever unenthusiastic/disinterested for a whole week 1.3 1.5 3.0 1.7 -0.4 -1.6 -0.9 -1.7 0.5 0.6 -1.6
Qualifications: None of the above 3.0 6.4 16.7 2.8 -0.1 -1.7 -1.4 -2.9 3.0 2.0 -4.1
Financial difficulties in last 2 years 0.3 0.3 0.6 -0.0 -0.7 -0.5 -0.5 -0.7 0.8 -0.8 0.3
Mouth/teeth dental problems 0.3 0.5 1.5 -0.9 0.8 0.3 0.5 0.7 -1.2 0.1 0.2
Heart attack 0.8 1.0 3.0 1.6 -0.7 -1.7 -0.3 -0.6 -0.8 0.6 0.8
Allergy 0.4 0.9 3.3 -0.9 -0.6 1.8 -0.9 0.1 0.4 -1.3 -0.2
Pain all over the body in last month 1.4 1.5 5.7 0.3 -2.4 -0.8 -2.4 -0.5 -0.1 -0.1 0.1
Diabetes (self-reported) 0.9 1.4 3.5 -1.2 -1.4 0.5 -0.8 -0.0 -0.7 -1.7 1.9
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 3.9 -0.5 1.0 0.7 1.2 1.2 -2.0 -0.3 1.1
Medication: Ramipril 0.3 0.4 0.7 0.9 -0.1 0.8 0.6 0.7 0.5 -0.8 0.2
Medication: Simvastatin 0.4 0.6 1.4 -0.6 0.5 0.4 0.9 1.2 -0.6 -0.6 0.9
Fluid intelligence score 0.7 1.4 4.4 -1.2 0.4 0.8 1.0 0.8 -1.5 -0.4 2.1
Illnesses of siblings 1.4 2.0 4.7 1.2 -1.9 -1.1 -1.5 -1.3 0.6 2.2 -0.8
Neuroticism score 3.0 6.4 14.2 3.8 1.1 -3.5 1.4 -2.2 1.3 3.6 -1.3
Weight 0.6 2.8 6.0 -1.3 -0.4 1.8 -0.1 2.4 -1.2 -2.3 2.1
Impedance of arm (right) 0.3 1.2 2.8 1.1 0.4 -1.7 0.8 -1.1 0.0 1.3 -1.3
Arm fat percentage (right) 1.0 3.9 6.8 -2.2 -0.3 1.6 0.3 2.5 -1.9 -2.5 2.6
Trunk fat-free mass 0.2 1.2 3.9 -0.2 0.5 1.6 0.4 2.0 -0.2 -1.3 0.9
Hip circumference 1.2 5.0 11.6 -2.4 -0.5 2.6 -0.3 2.4 -2.0 -3.4 2.4
Time employed in main current job 1.0 1.1 3.0 -0.9 0.2 1.1 0.1 1.7 -1.3 -0.6 1.3
Alcohol intake versus 10 years previously 2.2 3.4 5.1 2.1 -1.1 -1.8 -0.9 -1.9 2.1 2.2 -2.0
Father’s age at death 0.1 0.2 0.5 -0.2 0.2 0.6 -0.3 0.7 0.2 -0.4 -0.3
Worrier / anxious feelings 0.5 0.9 3.5 0.8 0.7 -1.9 0.7 -1.4 -0.1 0.7 0.3
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 2.4 1.4 1.6 -0.5 1.2 0.7 -0.4 1.2 0.4
Falls in the last year 1.6 2.1 4.8 0.1 -2.0 -1.2 -2.0 -2.2 1.4 0.4 -0.4
Hair/balding pattern: Pattern 3 0.7 1.0 5.9 -0.2 -0.5 0.7 -0.3 -1.0 0.4 -2.4 -0.5
Number of live births 0.9 1.3 6.0 1.2 0.1 0.6 0.2 0.7 2.5 -0.2 -1.3
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 4.2 1.4 -0.5 0.0 -0.5 -0.3 1.5 2.0 -2.0
Pulse rate 0.6 0.9 2.7 -0.5 0.7 0.1 0.9 1.6 -0.7 -0.8 1.5
Happiness 0.3 0.4 1.1 0.6 -0.1 -0.2 0.4 -1.0 -0.6 1.1 -0.4
Noisy workplace 1.7 2.1 5.4 0.6 -2.3 -1.2 -1.8 -2.0 1.0 -0.3 -1.3
Qualifications: A levels/AS levels or equivalent 1.5 3.2 9.8 -3.1 0.2 1.4 0.2 1.1 -1.6 -2.6 1.9
Serious illness, injury or assault of a close relative in last 2 years 1.0 1.2 3.5 0.4 1.5 0.8 1.9 1.1 -0.6 -0.7 0.9
Mouth/teeth dental problems: Dentures 0.6 1.0 3.9 2.0 -0.8 -1.3 -0.2 -0.5 1.0 0.6 0.3
Asthma 0.6 1.2 2.7 0.4 -1.1 -0.0 -1.2 -0.7 1.6 -1.2 -1.4
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.4 0.4 0.3 -1.1 0.6 -0.0 -0.4 1.2 -0.1
Medication: Cholesterol lowering 1.6 2.5 5.0 -0.7 0.9 1.0 1.6 2.2 -2.2 -1.3 2.1
Depression (self-reported) 0.5 0.6 1.5 0.7 -0.1 -0.8 -0.7 -0.6 1.2 0.2 -0.9
Medication: Lansoprazole 1.4 1.6 2.7 -1.6 0.8 1.6 0.7 1.3 -1.4 -1.2 1.2
Prospective memory result 0.8 1.0 4.4 0.4 -1.4 0.1 -2.1 -0.3 0.6 0.4 -0.5
Lung cancer (father) 0.5 0.6 2.6 1.1 -0.5 1.6 -0.4 -0.7 -0.1 -0.1 -0.4
Illnesses of mother 0.7 0.8 2.6 -0.1 -0.5 -0.9 -0.9 -1.0 0.8 0.9 -1.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.5 1.7 5.9 1.1 -0.4 -0.8 -0.5 -0.5 1.0 2.4 -2.1
Pulse wave Arterial Stiffness index 0.3 0.3 0.9 0.7 0.2 -0.3 0.2 1.0 0.8 0.4 0.2
Impedance of arm (left) 0.4 1.8 4.9 1.2 -0.0 -1.2 0.2 -2.0 0.9 1.2 -2.2
Arm fat mass (right) 1.1 4.4 8.3 -2.1 0.1 2.2 0.4 2.8 -1.8 -2.9 2.5
Trunk predicted mass 0.2 1.2 3.9 -0.2 0.5 1.7 0.4 2.0 -0.2 -1.4 0.8
Standing height 0.1 1.4 4.8 2.2 1.0 -0.6 1.1 0.5 1.0 0.8 -1.4
Length of working week for main job 1.0 1.1 2.5 -1.2 0.8 1.6 1.2 1.4 -0.3 -0.4 0.8
Exposure to tobacco smoke at home 0.5 0.6 1.0 0.9 -0.1 -0.9 -0.2 -0.8 0.9 0.8 -1.0
Breastfed as a baby 0.5 0.6 1.7 -0.7 1.3 0.3 1.2 0.3 -0.9 -0.2 -0.2
Tense / ‘highly strung’ 1.0 1.6 3.6 1.4 -1.0 -1.6 -0.6 -1.9 1.4 0.7 -0.8
Seen doctor (GP) for nerves, anxiety, tension or depression 1.4 2.2 6.1 2.3 -0.7 -2.5 -0.5 -1.4 1.2 1.0 -0.9
Hair/balding pattern: Pattern 4 0.3 0.7 1.4 1.1 0.5 0.4 0.4 1.2 1.1 0.9 -0.6
Birth weight of first child 3.1 5.7 16.9 -0.9 3.3 2.0 4.1 2.7 -1.9 0.5 1.3
Peak expiratory flow (PEF) 0.7 1.7 3.2 0.8 1.6 0.5 1.7 1.0 1.4 1.8 -1.1
Pulse wave reflection index 0.8 1.0 3.1 0.6 -0.1 0.5 -0.4 0.6 1.8 1.4 -1.4
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.7 1.2 0.5 -0.8 0.1 -0.2 -0.1 1.3 -0.9
Loud music exposure frequency 0.5 0.5 2.6 0.4 0.1 0.4 0.1 -0.7 0.9 0.1 -1.6
Qualifications: O levels/GCSEs or equivalent 1.6 2.6 7.5 -2.7 0.8 1.0 0.9 1.5 -1.9 -1.5 1.8
Mouth/teeth dental problems: Bleeding gums 0.2 0.3 0.7 -0.5 0.9 0.8 0.2 -0.2 0.2 -0.6 -0.1
Blood clot in the leg (DVT) 1.0 1.2 4.8 -0.2 0.7 -2.2 0.6 0.4 -0.7 1.6 1.1
Medication: Paracetamol 2.6 4.3 10.1 -0.8 3.2 1.2 2.9 2.7 -1.8 -0.0 1.8
Headache pain in last month 1.9 3.3 7.5 1.8 0.2 -2.6 -0.6 -2.0 1.5 2.7 -1.5
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 2.7 -0.3 0.7 -1.1 0.4 -0.8 1.1 1.6 -0.4
Glaucoma (self-reported) 1.9 2.3 5.2 -1.0 1.4 0.1 1.9 1.8 -1.8 -0.1 2.3
Gout (self-reported) 2.1 2.8 7.2 1.4 -2.7 -0.4 -2.2 -0.4 2.5 -0.1 -1.3
Hypothyroidism/myxoedema (self-reported) 0.6 1.1 2.8 1.7 0.5 -0.5 -0.6 -0.1 1.4 1.0 -1.6
Medication: Amlodipine 2.2 3.1 6.4 -0.7 1.9 1.7 1.5 2.5 -1.0 -2.4 1.5
Medication: Ventolin 100micrograms inhaler 0.8 1.0 2.5 -0.5 -0.5 1.5 -0.4 -0.2 1.4 -1.6 -0.8
Birth weight 0.2 0.4 2.2 0.4 0.7 0.5 0.1 1.5 0.1 0.5 -0.1
Chronic bronchitis/emphysema (mother) 2.2 2.6 8.8 3.0 -0.3 -2.6 0.1 -0.3 1.3 1.6 -0.8
High blood pressure (siblings) 0.6 0.8 1.9 -0.4 1.2 0.8 0.9 1.0 -0.8 -1.4 0.4
Forced vital capacity (FVC), Best measure 0.6 2.0 5.9 1.7 -0.7 -0.4 -0.8 -0.5 1.7 1.8 -2.4
Body fat percentage 0.6 2.4 4.8 -1.5 -1.2 1.0 -0.7 1.6 -1.4 -2.1 2.2
Leg fat percentage (right) 0.5 1.7 3.3 -1.6 -1.2 1.1 -0.8 1.1 -0.9 -1.7 1.8
Arm fat-free mass (right) 0.2 1.0 2.8 -0.3 -0.1 1.4 -0.3 1.7 -0.4 -1.3 1.0
Exposure to tobacco smoke outside home 1.8 2.4 7.2 1.4 0.5 -0.5 -0.1 -2.1 1.5 1.8 -2.7
Comparative body size at age 10 0.9 2.4 7.5 -1.3 -1.9 -1.4 -1.5 0.8 -0.7 -0.9 2.7
Number of full brothers 0.5 0.6 1.4 0.4 0.7 0.4 0.4 -0.7 0.8 -1.1 -1.2
Worry too long after embarrassment 0.7 1.2 4.0 1.4 1.2 0.4 2.0 0.3 0.5 0.9 0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 2.8 3.6 10.0 3.2 0.5 -2.8 -0.3 -1.4 0.7 2.5 -1.3
Wheeze or whistling in the chest in last year 0.7 1.3 3.9 0.3 0.4 2.0 -0.1 -0.1 1.8 -0.5 -1.7
Number of children fathered 0.8 1.0 2.9 -1.7 0.5 0.7 0.7 0.6 -0.4 -1.7 0.4
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.6 5.7 0.2 -1.0 -1.0 -0.4 -0.5 -2.1 0.4 2.4
Age at first live birth 0.6 1.0 2.3 -0.1 -0.5 1.5 0.3 0.8 -1.5 -1.2 1.0
Pulse wave peak to peak time 0.3 0.4 1.2 -0.8 -0.3 0.4 -0.1 -1.1 -0.8 -0.5 -0.3
Health satisfaction 0.7 0.9 2.9 -0.7 0.4 1.7 0.6 0.7 -1.1 -1.2 0.5
Shortness of breath walking on level ground 0.6 0.7 2.1 -0.6 0.0 -0.2 0.6 1.1 -1.1 0.4 1.5
Qualifications: College or University degree 1.8 5.8 14.6 -3.3 -0.3 1.5 0.3 2.4 -3.1 -1.8 3.8
Eye problems/disorders: None of the above 1.1 1.3 3.1 -0.4 -1.3 1.7 -1.7 -0.3 0.7 -1.2 -0.7
Mouth/teeth dental problems: Loose teeth 0.9 1.1 2.8 -0.7 1.0 0.4 0.5 1.5 -1.1 -0.8 1.7
Emphysema/chronic bronchitis 0.6 0.7 2.0 0.1 -1.0 0.8 -1.4 0.2 -0.1 -1.3 0.5
Medication for pain relief, constipation, heartburn 0.6 1.0 2.6 -0.0 -0.8 0.8 -0.8 -0.7 1.5 -0.9 -1.6
Neck or shoulder pain in last month 2.5 3.6 7.0 -1.4 2.6 1.2 1.5 2.3 -2.1 -1.6 1.8
Medication: Blood pressure 0.8 1.4 4.6 -0.1 -0.2 1.9 -0.4 0.8 -1.2 -2.1 0.6
Angina (self-reported) 0.5 0.6 3.5 -0.0 -0.2 -0.8 -0.4 0.1 -1.9 -0.0 0.7
Migraine (self-reported) 0.2 0.3 0.6 0.8 0.6 0.2 0.2 -0.7 0.2 -0.6 -0.5
Medication: Ibuprofen 0.8 1.0 3.5 0.9 0.1 -1.9 0.4 -0.3 0.1 1.7 -0.5
Medication: Allopurinol 1.3 1.7 3.3 1.8 -1.8 -0.2 -1.7 0.1 1.7 -0.4 -1.1
Medication: Omeprazole 1.5 1.8 4.1 -0.9 -1.5 -2.0 -1.6 -1.2 -0.3 1.6 0.9
Medication: Seretide 50 evohaler 0.4 0.4 1.0 -1.0 0.4 -0.6 0.9 0.3 -0.9 -0.2 0.3
Mean time to correctly identify matches 1.6 3.1 10.6 0.9 -2.8 -1.5 -3.3 -1.9 -0.3 0.1 -0.1
Heart disease (mother) 1.7 2.0 6.5 -0.6 1.0 0.6 1.6 0.8 -2.0 -0.9 2.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.9 1.6 1.0 1.1 -0.2 1.0 -1.0 1.0 0.4 -1.3
Whole body fat mass 0.8 3.2 7.0 -1.6 -0.9 1.6 -0.6 2.0 -1.7 -2.6 2.3
Leg fat mass (right) 0.6 2.5 5.1 -1.5 -1.1 1.4 -0.8 1.7 -1.3 -2.3 2.1
Arm predicted mass (right) 0.2 1.2 3.0 -0.3 -0.2 1.7 -0.4 1.7 -0.0 -1.6 0.8
Pulse rate, automated reading 0.1 0.4 1.6 -0.3 -0.1 0.3 0.7 0.6 -0.1 -1.3 0.5
Alcohol intake frequency. 1.8 4.3 10.3 3.2 0.8 -1.7 -0.5 -0.8 2.1 3.2 -2.2
Comparative height size at age 10 0.3 1.7 3.6 -1.1 -1.9 0.3 -1.5 0.5 -1.1 -1.9 1.2
Number of full sisters 0.7 0.9 3.7 -0.1 1.1 1.9 0.8 1.2 0.3 -0.4 0.0
Suffer from ‘nerves’ 1.1 1.7 6.2 2.5 0.7 -1.1 0.6 -1.1 1.6 0.8 -1.1
Overall health rating 0.9 2.0 3.5 -0.3 1.4 1.1 1.4 1.9 -1.6 -1.1 1.7
Chest pain or discomfort 0.4 0.6 2.0 1.1 0.0 -0.2 -0.1 0.1 0.9 1.4 -0.8
Had major operations 0.7 0.8 2.3 0.3 0.4 0.7 0.2 -0.4 1.1 -1.5 -1.3
Age at last live birth 0.5 0.7 2.8 0.1 0.3 1.0 1.3 1.7 -0.1 -0.0 0.2
Family relationship satisfaction 1.0 1.2 2.9 -0.9 -1.7 0.3 -1.1 -1.4 -0.5 -1.5 -0.2
Leg pain on walking 1.0 1.2 2.4 -1.1 -1.2 0.4 -1.0 0.8 -1.6 -0.8 1.4
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 1.8 -0.6 0.2 0.7 0.2 -0.1 1.0 -1.3 -0.7
Commuting to job workplace: Car/motor vehicle 0.3 0.3 1.0 -0.9 0.5 1.0 -0.1 -0.2 -0.1 -0.4 -0.2
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.3 -0.2 0.3 1.1 0.9 -0.0 -0.4 -0.6 -0.4
Medication: Aspirin 0.5 0.7 1.7 -0.2 -0.8 -0.4 -0.6 -0.1 -1.2 -1.3 1.1
Supplements: Vitamin C 1.1 1.3 3.2 1.8 -0.5 -0.4 -0.9 -0.2 1.2 1.7 -1.3
Knee pain experienced in last month 0.7 1.0 3.2 -0.2 1.4 0.3 1.8 1.0 -0.7 -0.2 1.2
Hypertension (Self-reported) 1.6 4.4 12.5 -1.5 1.7 3.5 1.2 2.1 -0.9 -3.2 0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.3 1.5 3.7 -1.9 -1.3 -0.2 -0.8 -0.7 -1.3 -0.4 1.9
Illnesses of father: Heart disease 1.9 2.6 4.7 -2.1 0.4 0.7 1.7 1.9 -2.2 0.2 2.1
Illnesses of siblings: Diabetes 0.8 1.0 4.0 1.2 -0.3 -2.0 -0.6 -1.0 0.0 0.7 0.4
Smoking status: Previous 0.4 0.6 1.8 0.7 0.6 -0.8 0.5 0.3 1.3 -0.4 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.8 1.8 0.4 1.2 0.2 0.9 1.4 1.0 0.6 -1.0
Whole body fat-free mass 0.3 1.7 5.1 -0.6 0.2 1.9 0.2 2.2 -0.5 -1.8 1.2
Leg fat-free mass (right) 0.5 2.5 7.6 -1.1 0.2 1.8 0.5 2.8 -0.9 -2.0 1.7
Arm fat percentage (left) 0.9 3.7 7.3 -2.2 -0.5 1.9 0.0 2.1 -1.7 -2.7 2.3
Average weekly red wine intake 1.6 2.3 4.6 -2.1 0.9 1.9 1.1 1.6 -1.5 -1.4 1.3
Handedness (chirality/laterality): Left-handed 0.4 0.4 1.8 0.2 1.3 -0.2 0.6 0.5 -0.6 0.4 -0.7
Mood swings 1.3 2.3 8.4 1.4 0.5 -2.9 1.1 -1.4 -0.1 2.1 0.4
Loneliness, isolation 3.8 5.3 10.0 2.5 -1.0 -3.1 -1.0 -3.1 1.9 3.2 -1.1
Long-standing illness, disability or infirmity 1.4 2.1 6.9 -1.6 -0.2 0.5 -0.3 1.1 -1.0 -2.6 2.1
Ever had bowel cancer screening 1.0 1.1 2.2 -0.8 1.1 1.3 0.7 1.5 -0.8 -1.3 0.7
Diabetes diagnosed by doctor 1.0 1.6 3.5 -1.6 -0.9 1.3 -0.2 0.6 -0.9 -1.9 1.8
Ever had stillbirth, spontaneous miscarriage or termination 1.7 1.8 3.6 -0.9 1.1 1.7 1.6 1.9 -0.1 0.6 1.8
Friendships satisfaction 0.6 0.8 3.0 -0.8 -0.9 0.2 -0.6 -0.4 -1.7 -1.1 0.5
Qualifications: nursing, teaching 2.3 3.6 10.2 -2.4 -0.9 -0.8 -0.2 0.6 -3.2 -1.0 3.2
Commuting to job workplace: Walk 0.7 0.7 1.5 1.1 0.6 -1.2 0.8 -0.8 0.5 1.0 -0.6
Eye problems/disorders: Cataract 0.8 1.0 3.4 0.3 1.6 -0.0 1.8 0.4 -0.2 1.1 -0.3
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 2.8 1.1 -0.9 -0.8 -1.0 -1.2 1.7 0.6 -1.6
Medication for cholesterol 0.9 1.3 2.5 1.6 -0.6 -1.3 -1.0 -0.5 1.6 0.7 -1.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.5 3.0 8.4 1.3 -2.0 -1.1 -1.9 -2.9 0.4 1.7 -1.6
Back pain experienced in last month 1.9 2.8 6.0 -1.3 2.5 1.3 2.2 2.4 -0.8 -0.9 0.8
Mineral and other dietary supplements 2.0 2.7 9.7 1.7 -0.6 -2.3 -0.6 -1.1 0.8 3.1 -1.2
Breast cancer (self-reported) 0.2 0.3 1.5 0.2 0.2 -0.1 0.0 1.2 0.8 -0.3 0.2
Asthma (self-reported) 0.6 1.1 2.4 0.1 -0.9 0.3 -1.1 -0.7 1.5 -1.4 -1.4
Osteoporosis (self-reported) 0.6 0.8 2.5 -0.3 1.3 0.6 1.6 0.7 -0.2 0.1 0.9
Osteoarthritis (self-reported) 0.9 1.2 4.7 -0.9 0.5 0.9 -0.0 2.2 -0.5 -1.0 1.3
Medication: Aspirin 0.7 0.9 1.8 0.1 -1.3 -0.8 -1.1 -0.6 -1.1 -1.2 0.9
Medication: Gliclazide 1.2 1.4 4.3 -1.3 -1.3 0.8 -0.9 -0.1 -0.5 -2.1 1.2
Illnesses of father: None of the above (group 1) 0.3 0.4 1.1 -0.3 -0.1 1.0 -0.6 -0.5 0.8 0.1 -0.9
Smoking status: Current 0.8 1.3 4.2 1.1 0.4 -0.6 0.5 -0.6 2.1 1.7 -0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.2 2.3 0.9 -1.3 -1.0 -1.2 -1.5 -1.2 0.3 -0.7
Whole body water mass 0.3 1.9 6.2 -0.6 0.4 1.9 0.4 2.5 -0.5 -1.8 1.3
Leg predicted mass (right) 0.5 2.6 7.8 -1.1 0.3 1.9 0.5 2.8 -0.9 -2.1 1.7
Arm fat mass (left) 0.8 3.5 7.0 -2.0 -0.4 2.0 -0.0 2.2 -1.6 -2.7 2.2
Number of self-reported non-cancer illnesses 1.9 3.3 5.4 -1.4 2.3 1.8 1.5 1.9 -1.7 -2.1 1.6
Average weekly champagne plus white wine intake 1.2 1.7 4.6 -1.0 1.0 2.1 0.8 0.8 -1.2 -1.9 0.8
Miserableness 3.2 5.5 13.2 3.0 1.2 -2.8 1.6 -2.2 1.4 3.6 -1.9
Guilty feelings 1.4 2.0 4.8 2.0 1.3 -1.0 1.8 0.4 1.3 2.2 -0.2
Wears glasses or contact lenses 3.9 4.5 12.9 -1.8 0.9 1.2 1.3 1.7 -3.6 -1.6 3.2
Ever taken oral contraceptive pill 0.9 1.0 2.5 0.9 -1.4 -0.4 -0.9 -0.2 1.6 0.2 -1.3
Hearing aid user 1.6 1.8 4.8 1.7 1.2 -0.9 1.1 -0.6 1.2 1.1 -2.2
Mother’s age at death 1.3 1.6 4.6 -1.0 1.3 1.2 1.4 2.2 -0.2 -1.4 0.6
Financial situation satisfaction 0.9 1.1 3.9 -0.9 -0.8 0.9 -0.4 -0.8 1.2 -2.0 -0.9
Tinnitus: Yes, now most or all of the time 1.1 1.3 3.2 -0.4 1.8 0.8 1.7 0.8 1.4 -0.1 -0.9
Commuting to job workplace: Public transport 0.4 0.4 1.5 0.1 -1.2 -0.7 -0.5 -0.6 -0.5 0.5 0.4
Eye problems/disorders: Glaucoma 1.6 1.9 4.5 -0.3 1.6 -1.2 1.8 0.8 -2.1 0.2 1.6
Medication: Blood pressure 0.5 0.9 1.9 -0.3 1.3 1.4 1.4 0.9 -0.4 -0.9 0.5
Pain type(s) experienced in last month: Hip pain 2.1 2.6 5.6 -1.0 2.1 1.4 2.0 1.2 -1.4 -2.4 1.0
Supplements: Fish oil (including cod liver oil) 2.4 3.1 9.0 -2.3 -0.3 2.0 0.1 0.7 -1.7 -3.0 1.8
High cholesterol (Self-reported) 2.6 4.6 6.5 -2.5 1.6 2.3 1.9 2.5 -2.3 -2.0 1.9
Medication: Bendroflumethiazide 1.4 2.2 4.9 -1.5 1.0 2.2 1.3 0.9 -1.2 -2.2 0.8
Medication: Paracetamol 1.5 2.3 5.9 -0.1 2.4 0.3 2.1 2.4 -1.0 0.2 1.2
Medication: Lisinopril 0.9 1.2 4.0 -0.9 0.7 0.5 0.5 0.6 -1.3 -2.0 1.4
Medication: Atorvastatin 1.4 1.7 4.1 -1.2 -0.3 0.9 0.5 0.6 -1.9 -1.8 2.0
Illnesses of father: High blood pressure 1.3 1.6 5.3 1.2 1.7 -0.3 2.3 0.7 1.0 1.1 -0.7
Alcohol drinker status: Never 1.2 1.4 3.6 1.9 0.7 -1.6 0.3 -0.5 -0.9 1.8 -0.3
Ever smoked 0.5 0.9 2.4 1.1 0.8 -0.7 0.9 -0.2 1.5 0.8 -1.1
Basal metabolic rate 0.3 1.8 5.3 -0.7 0.1 1.8 0.1 2.3 -0.6 -1.8 1.3
Leg fat percentage (left) 0.6 2.2 4.9 -1.8 -1.1 1.0 -0.7 1.4 -1.3 -1.7 2.2
Arm fat-free mass (left) 0.3 1.4 4.0 -0.6 0.1 1.6 -0.0 2.0 -0.6 -1.4 1.2
Number of operations (self-reported) 0.5 0.8 2.8 0.6 0.8 -0.3 0.4 -0.8 0.9 0.7 -1.7
Average weekly beer plus cider intake 5.7 8.3 13.9 3.4 -1.6 -3.7 -2.1 -3.5 2.2 2.6 -3.2
Irritability 2.6 4.4 13.0 2.2 0.4 -3.2 1.0 -2.3 -0.8 3.6 -0.5
Risk taking 0.4 0.6 1.8 -1.3 -0.4 -0.2 -0.0 -1.1 -0.9 0.6 -0.4
Ever had prostate specific antigen (PSA) test 0.3 0.4 0.9 0.4 -0.5 -0.8 -0.2 0.1 -0.8 -0.4 1.0
Fractured/broken bones in last 5 years 0.8 1.0 3.7 0.6 -0.5 -0.9 -1.0 0.6 1.9 0.4 -1.2
Age started oral contraceptive pill 0.9 1.1 3.7 -0.2 1.1 1.1 0.4 1.2 0.9 -1.9 -0.9
Diastolic blood pressure, automated reading 0.3 0.9 1.8 -0.6 0.7 1.1 0.7 0.8 -0.8 -1.3 1.3
Ever depressed for a whole week 0.3 0.3 1.1 0.4 0.8 -0.1 0.6 -0.2 -0.2 0.5 -1.0
Unable to work because of sickness or disability 0.5 0.7 1.9 0.5 -1.0 -1.0 -1.4 -0.5 0.9 -0.4 -0.4
Commuting to job workplace: Cycle 0.8 1.0 2.4 0.4 -1.2 0.2 -1.5 -0.5 1.3 -1.0 -1.0
Myopia 0.4 0.5 2.4 0.6 -0.1 0.8 0.0 -1.5 -0.6 -0.6 -0.2
Vascular/heart problems diagnosed by doctor 1.1 3.1 8.9 1.2 -1.7 -3.0 -1.1 -1.7 0.6 2.7 -0.6
Cholesterol lowering medication 0.7 1.0 2.2 -1.5 0.5 0.8 0.9 0.7 -1.3 -0.8 1.2
Medication: Omeprazole (e.g. Zanprol) 1.3 1.5 2.6 -1.0 -1.5 -1.5 -1.6 -0.8 -0.1 1.6 0.9
Pain experienced in last month 0.6 1.0 2.6 0.4 -1.5 -0.3 -1.0 -1.6 1.0 0.1 -0.9
Supplements: Calcium 0.8 0.9 3.5 0.3 -0.8 -0.3 -1.0 -0.6 1.9 0.7 -0.9
Basal cell carcinoma (self-reported) 0.9 1.1 2.1 -1.1 0.7 0.3 0.4 1.0 -1.4 -1.3 1.4
Heart attack/myocardial infarction (self-reported) 1.0 1.3 4.0 1.6 -0.8 -2.0 -0.5 -0.9 -0.9 0.7 1.0
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 4.0 -0.5 0.5 -2.0 0.4 0.6 -1.0 1.2 1.5
Heart disease (siblings) 2.3 2.8 4.8 -1.9 1.7 1.0 2.2 0.5 -1.5 -1.9 1.9
Alcohol drinker status: Previous 1.5 1.7 5.5 1.4 1.3 -1.7 0.6 0.6 0.4 2.3 -0.7
Pack years of smoking 0.3 0.5 0.7 0.2 -0.5 -0.2 -0.8 -0.8 0.9 -0.8 -0.7
Impedance of whole body 0.9 4.4 8.7 2.1 -0.5 -2.3 -0.5 -3.0 1.5 2.5 -2.8
Leg fat mass (left) 0.8 2.9 5.7 -1.7 -1.1 1.4 -0.7 1.9 -1.4 -2.4 2.3
Arm predicted mass (left) 0.3 1.4 4.2 -0.6 0.0 1.6 -0.2 2.1 -0.4 -1.6 1.3