Hub : Genes

TMEM140

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0320	0.0160	1.6e-02	-0.002	0.015	-0.001	0.013	0.000	9.7e-01	5.0e-03	5.0e-01	8.9e-03	3.4e-01
2	NTR	Blood	0.0394	0.0107	5.6e-10	0.044	0.030	0.046	0.027	0.022	4.7e-14	4.7e-10	1.2e-14	4.3e-09	1.2e-07
3	ROSMAP	Brain Pre-frontal Cortex	0.0445	0.0180	9.4e-04	0.010	0.018	0.016	0.018	0.017	1.4e-02	2.1e-03	3.2e-03	2.0e-03	2.3e-03
4	YFS	Blood	0.2371	0.0298	0.0e+00	0.413	0.397	0.413	0.411	0.412	1.9e-148	5.7e-141	1.8e-148	2.8e-147	4.9e-148
5	TCGA	Breast Invasive Carcinoma	0.0373	0.0251	1.8e-03	0.013	0.007	0.004	NA	0.010	9.6e-04	9.5e-03	3.7e-02	NA	3.1e-03
6	TCGA	Glioblastoma Multiforme	0.0930	0.0600	6.3e-03	0.086	0.066	0.047	NA	0.046	1.4e-03	4.7e-03	1.5e-02	NA	1.6e-02
7	TCGA	Head and Neck Squamous Cell Carcinoma	0.0513	0.0289	8.0e-06	0.051	0.039	0.059	NA	0.041	1.8e-06	2.8e-05	3.6e-07	NA	1.8e-05
8	TCGA	Liver Hepatocellular Carcinoma	0.0960	0.0610	1.3e-03	0.090	0.051	0.072	NA	0.080	5.2e-05	1.9e-03	2.7e-04	NA	1.3e-04
9	TCGA	Lung Adenocarcinoma	0.0524	0.0363	7.2e-05	0.026	0.016	0.026	NA	0.025	5.0e-04	5.2e-03	4.2e-04	NA	5.6e-04
10	TCGA	Stomach Adenocarcinoma	0.0400	0.0280	4.1e-03	0.038	0.017	0.008	NA	0.020	9.4e-04	1.9e-02	8.4e-02	NA	1.3e-02
11	TCGA	Testicular Germ Cell Tumors	0.1880	0.1140	3.2e-03	0.032	0.038	0.004	NA	0.014	2.6e-02	1.8e-02	2.3e-01	NA	9.9e-02
12	TCGA	Uterine Corpus Endometrial Carcinoma	0.1500	0.0830	4.3e-03	0.130	0.069	0.049	NA	0.107	1.8e-04	5.6e-03	1.7e-02	NA	6.6e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	2.5	4.0	8.0	2.1	-2.0	1.7	-2.3	-2.1	-2.2	-2.0	-2.3	-1.1	-0.0	-2.8	-2.0
Bipolar Disorder or Schizophrenia	2.1	5.2	11.0	2.4	-2.1	1.5	-2.7	-2.3	-2.7	-2.4	-2.6	-1.1	-0.0	-3.3	-2.4
Depressed Affect (Nagel 2018)	0.1	0.2	0.6	0.6	0.4	0.5	0.6	0.2	0.6	0.1	0.6	0.3	-0.3	0.5	0.8
Depression (Nagel 2018)	0.1	0.2	0.9	0.9	0.1	0.6	-0.1	0.5	0.2	-0.4	-0.1	0.5	0.1	-0.1	0.0
Intelligence (Savage-Jansen 2018)	0.7	2.0	7.1	1.5	-1.3	-1.5	-1.0	-1.2	-1.7	-0.1	-1.0	-1.7	-2.7	-0.8	1.0
Neuroticism (Nagel 2018)	0.2	0.4	2.7	0.5	-0.1	-0.4	0.2	-0.3	0.0	0.3	0.2	-0.5	-0.9	0.5	1.6
Schizophrenia (2018)	0.8	1.7	3.6	1.5	-1.2	0.6	-1.6	-1.2	-1.6	-1.4	-1.4	-0.5	-0.0	-1.9	-1.4
Schizophrenia vs Biploar Disorder	1.3	1.7	2.9	-0.5	1.4	-0.9	1.4	1.7	1.2	1.7	1.6	1.1	0.3	1.6	1.4
Worry (Nagel 2018)	0.3	0.7	4.1	-0.2	-0.2	-1.3	0.2	-0.1	-0.2	1.0	0.2	-0.4	-1.0	0.4	2.0
Alzheimer’s Disease (in mother)	0.5	0.5	2.6	-1.3	0.3	0.3	0.1	-0.0	0.3	-1.1	-0.0	0.8	0.3	-0.3	-1.6
Alzheimer’s Disease (in father)	0.3	0.3	2.0	-1.4	0.3	-0.8	0.6	0.1	0.6	-0.1	0.5	0.3	-0.1	0.7	0.3
Alzheimer’s Disease (including proxy)	1.0	1.5	5.6	-2.4	1.3	0.1	1.2	0.9	1.5	-0.1	1.1	1.5	1.0	0.9	-0.9
Crohns Disease (2017)	0.7	1.5	3.0	0.3	1.4	-0.9	1.4	0.2	1.3	1.7	1.4	1.2	0.5	1.7	1.1
Irritable Bowel Disease (IBD)	0.9	2.1	5.6	-0.3	1.2	-1.1	1.4	1.6	1.1	2.2	1.5	0.7	-0.6	1.7	2.4
Ulcerative Colitis (UC)	1.5	2.8	8.5	-1.2	1.0	-1.3	1.3	2.5	1.0	2.3	1.5	0.4	-1.1	1.6	2.9
Major Depression (MDD)	0.2	0.3	1.1	-0.1	-0.4	-0.9	-0.4	0.3	-0.5	0.2	-0.3	-0.2	-1.1	-0.6	0.3
Reaction Time	0.9	1.8	3.1	0.6	-1.6	0.3	-1.6	-1.3	-1.8	-1.6	-1.7	-1.0	-0.5	-1.8	-1.1
Verbal and Numeric Reasoning (VNR)	0.2	0.4	2.2	-0.2	0.0	-1.5	0.2	-0.2	-0.1	0.5	0.1	-0.1	-1.2	0.3	0.5
Breast Cancer	0.8	1.9	5.7	0.3	-1.6	-1.4	-1.2	-1.8	-1.8	-1.0	-1.1	-2.4	-1.1	-0.7	0.5
Ovarian Cancer	1.0	1.3	2.7	-0.1	1.1	-0.3	1.0	1.6	1.4	1.5	1.2	1.1	0.9	1.1	1.3
Prostate Cancer	0.6	0.8	1.4	-1.1	1.2	0.3	1.1	-0.1	1.1	0.5	1.1	1.0	1.1	0.8	-0.5
Age at First Birth	0.4	0.6	2.5	1.6	-0.5	1.1	-0.7	-0.1	-0.6	-0.7	-0.8	-0.7	0.3	-0.8	-0.7
Bipolar Disorder (2011)	4.6	4.5	8.7	2.6	-2.0	2.5	-2.5	-1.5	-2.2	-1.8	-2.4	-1.3	0.7	-3.0	-1.8
Body Mass Index (BMI) (2010)	1.7	2.4	9.1	1.5	-1.4	3.0	-1.6	0.7	-1.1	-1.4	-1.5	-1.0	0.8	-1.6	-1.6
Coronary Artery Disease (CAD)	0.6	0.8	1.6	1.3	-1.1	1.0	-1.0	-0.1	-1.1	-0.7	-1.0	-1.0	-0.3	-0.7	-0.3
Crohns Disease (2012)	0.3	0.4	1.9	1.4	-0.7	-0.3	-0.7	-0.6	-0.8	-0.0	-0.5	-0.7	-0.4	-0.4	0.5
Mean Putamen Volume	0.2	0.3	1.0	0.4	0.3	0.6	0.0	0.8	0.3	-0.6	0.1	0.5	1.0	0.2	-0.6
Fasting Glucose	0.6	0.8	3.3	-0.4	-0.0	1.8	-0.2	1.3	0.1	-0.4	-0.3	0.4	1.6	-0.4	-0.9
HbA1C	0.4	0.4	1.2	0.9	-0.2	1.1	-0.4	0.6	-0.0	-0.6	-0.4	0.5	0.6	-0.7	-1.0
HDL Cholesterol	2.4	4.0	8.6	-2.0	1.9	-2.2	2.4	0.7	1.9	2.1	2.5	0.9	-0.1	2.9	2.2
LDL Cholesterol	0.5	0.7	2.0	-0.2	-0.9	-0.1	-0.7	-0.9	-1.1	0.1	-0.7	-1.2	-1.4	-0.9	0.7
Lupus	1.1	1.6	2.9	-1.1	1.3	-0.7	1.4	1.6	1.3	1.7	1.5	0.6	-0.9	1.3	1.5
Neuroticism (2016)	0.7	1.0	5.7	-0.9	0.4	-0.9	0.6	2.4	0.7	0.8	0.5	0.3	-0.9	0.8	1.3
Primary Biliary Cirrhosis	1.2	1.7	5.0	2.2	-1.3	0.7	-1.5	0.2	-1.1	-1.4	-1.5	-0.3	0.4	-1.8	-1.3
Rheumatoid Arthritis	3.2	4.4	10.3	-1.9	1.7	-2.3	2.2	1.0	1.6	2.7	2.3	0.7	-1.2	2.6	3.2
Schizophrenia (2014)	2.2	4.8	8.8	2.5	-2.3	0.8	-2.7	-1.8	-2.8	-2.2	-2.6	-1.6	-0.3	-3.0	-2.0
Triglycerides	0.6	1.0	5.2	0.1	0.7	2.3	0.3	0.9	1.0	0.2	0.2	1.2	1.1	-0.0	-1.3
Type 2 Diabetes (T2D) (2012)	0.5	0.6	0.9	0.6	-1.0	1.0	-0.9	-0.1	-0.8	-0.9	-0.8	-0.8	-0.4	-0.8	-0.6
Ulcerative Colitis	2.1	3.1	8.2	-1.2	1.3	-1.9	1.5	2.3	1.3	2.0	1.8	0.9	-1.3	1.7	2.9
Blood Eosinophil Count	2.0	15.1	26.0	2.0	-5.0	-1.7	-4.6	-3.5	-5.1	-4.4	-4.8	-4.8	-2.8	-3.8	-1.5
Blood Platelet Count	0.8	9.7	14.6	-3.8	3.5	-3.6	3.4	2.0	3.1	3.8	3.3	3.3	1.1	3.1	2.1
Blood Red Count	0.9	9.1	29.5	-1.6	2.0	-5.4	3.0	-0.2	1.6	2.6	3.0	0.3	-3.8	3.5	4.4
Blood White Count	0.1	0.7	6.2	-2.5	0.4	0.1	0.1	0.8	0.3	-0.3	0.0	0.4	0.4	0.3	-1.2
Heel T-Score	0.2	1.6	5.9	0.9	-1.0	0.6	-1.4	-0.5	-0.9	-2.0	-1.4	-0.5	0.8	-1.2	-2.4
BMI	0.9	5.0	7.9	2.2	-2.7	2.8	-2.7	-0.1	-2.4	-2.1	-2.7	-2.6	-0.3	-2.3	-1.4
Height	0.2	4.7	53.1	7.3	0.1	-0.0	-0.1	0.8	0.2	0.5	0.1	0.6	-0.3	-0.3	1.4
Waist Hip Ratio (WHR)	1.1	4.9	8.3	0.4	-2.5	0.9	-2.8	-2.5	-2.8	-2.5	-2.9	-1.7	0.5	-2.7	-2.1
Systolic Blood Pressure	1.3	6.6	12.9	-3.0	2.9	2.5	2.3	0.7	3.0	0.8	2.1	3.5	3.6	2.0	-2.5
Smoking Status	0.5	1.2	3.2	-1.3	1.1	-0.3	1.0	1.1	1.1	0.8	1.1	1.2	1.8	1.3	0.8
Allergy or Eczema	1.4	3.8	12.0	0.4	-1.5	-2.5	-0.8	-2.4	-1.8	0.2	-0.8	-2.7	-3.5	0.0	2.7
Cardiovascular Disease	1.3	4.3	12.5	-2.6	1.8	2.0	1.3	2.0	2.4	1.0	1.0	2.9	3.5	1.0	-1.6
Hypothyroidism (self reported)	2.0	4.6	8.0	1.0	-2.8	-0.1	-2.5	-1.3	-2.8	-1.9	-2.6	-2.7	-2.6	-2.5	-0.4
Respiratory disease	0.1	0.3	0.8	-0.2	-0.5	-0.1	-0.5	-0.9	-0.7	-0.5	-0.5	-0.4	-0.4	-0.6	-0.5
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.7	0.3	-0.1	-0.9	0.1	0.4	-0.2	0.3	0.1	-0.1	-0.8	0.5	0.7
Lung FEV1/FVC ratio	1.3	6.5	24.1	-2.4	-0.2	-4.9	0.9	0.0	-0.5	1.2	1.0	-2.3	-4.7	1.8	3.7
Lung FVC	0.9	4.5	11.3	2.0	-1.2	3.2	-1.9	-1.3	-1.4	-2.8	-1.9	-0.7	2.0	-2.2	-3.4
Neuroticism	0.2	0.5	1.2	1.0	-0.9	-0.3	-0.5	-0.3	-0.6	-0.6	-0.6	-1.1	-0.9	-0.1	1.0
Chronotype (morning person)	0.4	1.0	3.4	0.8	1.3	1.2	0.4	-0.4	0.8	0.3	0.5	1.8	1.3	-0.0	-1.4
Hair Pigment	0.1	2.2	3.3	-0.9	1.7	1.7	1.5	1.5	1.8	1.1	1.4	1.8	1.8	1.6	-0.2
Tanning	0.2	2.8	7.2	-1.9	1.4	-2.7	1.9	-0.2	1.2	1.5	1.9	0.5	-1.4	1.7	2.1
Hand grip strength (left)	0.1	0.2	0.6	0.4	0.0	-0.5	-0.1	-0.7	-0.1	-0.4	-0.1	0.1	-0.2	-0.6	-0.8
Number of treatments/medications taken	0.1	0.2	0.6	-0.1	-0.4	0.0	-0.6	-0.3	-0.8	-0.3	-0.5	0.2	-0.2	-0.8	0.3
Average weekly spirits intake	0.8	1.0	2.2	0.6	1.1	-1.3	1.1	-1.1	0.4	1.5	1.1	0.4	-0.1	1.1	1.1
Sensitivity / hurt feelings	0.2	0.3	1.0	0.3	0.6	0.5	0.7	-0.4	0.5	0.1	0.6	0.2	-0.7	1.0	0.2
Frequency of depressed mood in last 2 weeks	0.4	0.6	5.0	0.4	-0.1	-0.6	0.1	2.2	0.2	0.3	0.1	0.1	-0.3	-0.0	1.1
Hearing difficulty/problems: Yes	0.3	0.4	1.7	-0.8	0.2	0.5	0.0	-1.1	0.1	-0.6	-0.0	0.4	0.7	-0.1	-1.3
Relative age of first facial hair	1.2	2.5	7.7	-1.7	1.7	-2.8	1.6	-0.9	1.1	1.2	1.9	0.8	-0.5	1.9	1.6
Other serious medical condition/disability diagnosed by doctor	2.5	3.3	6.1	1.8	-2.1	1.1	-2.0	-2.3	-2.4	-1.5	-1.9	-2.5	-0.9	-1.7	-0.7
Ever used hormone-replacement therapy (HRT)	1.0	1.3	2.8	0.4	-1.6	-0.1	-1.5	-0.4	-1.7	-1.2	-1.3	-1.5	-1.1	-1.2	-0.0
Ever had hysterectomy (womb removed)	0.5	0.5	1.8	0.2	-0.9	-0.5	-0.7	-0.2	-0.8	-0.5	-0.8	-0.7	-1.3	-0.8	-0.2
Systolic blood pressure, automated reading	0.3	0.8	2.7	-0.6	1.0	1.7	0.7	0.3	0.8	0.1	0.7	0.9	0.6	0.7	-1.3
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.3	-0.9	0.3	-1.1	0.5	-0.0	-0.1	0.4	0.6	-0.1	-1.1	0.8	0.6
Angina	0.6	0.8	1.8	-0.5	1.0	-0.9	1.0	0.1	0.6	1.2	1.1	0.6	-0.4	1.1	1.3
Medication for hormone replacement therapy	0.5	0.6	2.2	0.8	-0.7	-0.4	-0.5	0.4	-0.8	0.1	-0.4	-0.7	-1.2	-0.2	1.5
Vitamin and mineral supplements	0.4	0.5	1.1	-0.5	0.9	-0.2	1.0	-0.4	0.9	0.6	0.8	0.8	0.5	1.0	-0.5
Supplements: Zinc	0.6	0.7	1.2	0.9	-0.9	0.0	-1.0	0.1	-1.1	-0.4	-0.8	-1.0	-1.1	-1.1	0.2
Medication: Co-codamol	0.8	0.9	1.6	0.1	-1.2	0.1	-1.2	-1.2	-1.2	-1.1	-1.2	-1.2	-0.5	-1.0	0.0
Medication: Metformin	0.7	1.0	2.2	0.9	-1.3	-0.3	-1.1	-0.2	-1.4	-0.6	-1.0	-1.5	-1.3	-0.6	0.5
Diabetes (father)	0.4	0.5	1.4	1.1	0.2	-0.3	0.5	-0.9	0.1	0.5	0.5	-0.6	-0.9	0.8	1.2
Diabetes (mother)	0.2	0.3	0.7	-0.4	-0.6	-0.4	-0.2	0.6	-0.3	-0.8	-0.5	-0.2	-0.8	-0.5	-0.2
Severe depression (siblings)	1.3	1.4	5.4	0.9	-1.2	0.1	-0.9	-2.3	-1.3	-1.2	-1.0	-1.7	-1.0	-0.4	0.1
Pack years adult smoking proportion	2.1	3.2	7.6	0.9	-1.8	2.2	-2.1	0.1	-1.6	-2.2	-2.2	-0.9	0.3	-2.8	-1.9
Impedance of leg (right)	0.1	0.7	3.1	1.0	-0.1	0.3	-0.7	-1.7	-0.7	-0.4	-0.4	0.5	1.2	-0.8	-0.5
Leg fat-free mass (left)	0.3	1.8	11.0	3.3	-0.7	1.9	-0.6	2.0	-0.0	-0.4	-0.7	-0.3	-0.1	-0.9	-0.4
Trunk fat percentage	1.7	6.7	11.0	3.3	-3.3	2.6	-3.2	0.1	-2.6	-2.7	-3.3	-3.0	-0.0	-2.5	-1.3
Hand grip strength (right)	0.1	0.3	1.1	-0.1	-0.2	-0.4	-0.3	-0.9	-0.3	-0.8	-0.3	0.0	-0.5	-0.8	-1.0
Townsend deprivation index at recruitment	1.3	1.8	4.9	-0.3	-2.0	-0.9	-1.3	-0.5	-1.7	-1.1	-1.4	-2.2	-1.7	-0.7	0.9
Current tobacco smoking	0.5	0.8	1.7	-0.4	-1.3	0.2	-1.3	-0.3	-1.1	-1.2	-1.3	-0.9	0.2	-1.1	-0.3
Average weekly fortified wine intake	0.3	0.4	1.3	0.8	0.7	0.4	0.2	-0.8	0.4	-0.1	0.1	1.1	0.4	-0.1	-1.1
Maternal smoking around birth	0.2	0.3	0.9	0.4	-0.9	0.2	-0.7	0.4	-0.3	-0.6	-0.9	-0.3	-0.3	-0.7	0.0
Fed-up feelings	0.4	0.8	2.2	-0.3	0.8	-0.1	0.9	1.3	0.9	0.9	1.0	0.6	-0.1	0.8	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.7	0.5	0.8	1.2	0.5	1.7	1.0	-0.0	0.5	1.5	1.4	0.2	-0.5
Relative age voice broke	1.2	1.9	3.7	-1.2	1.7	-1.5	1.6	-0.5	1.0	1.5	1.9	0.8	-0.7	1.8	1.2
Taking other prescription medications	0.2	0.3	0.7	0.1	-0.6	-0.1	-0.6	-0.5	-0.8	0.1	-0.6	-0.5	-0.3	-0.5	0.7
Age when periods started (menarche)	0.3	0.7	1.9	0.4	-0.7	-0.4	-0.9	-1.4	-1.0	-0.7	-0.8	-0.7	-0.7	-1.0	-0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	2.1	-1.4	0.5	-0.1	0.4	0.9	0.5	0.5	0.4	0.7	-0.2	0.1	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	2.8	0.9	-1.3	0.0	-1.3	-1.4	-1.6	-1.0	-1.1	-1.7	-1.3	-1.3	-0.6
Tinnitus: Yes, but not now, but have in the past	2.5	2.7	4.5	2.1	-1.8	1.0	-1.8	-1.6	-1.9	-1.9	-1.9	-1.8	-0.3	-1.5	-1.1
Qualifications: CSEs or equivalent	0.2	0.3	1.6	-0.5	-0.0	-0.2	0.1	1.3	0.3	-0.0	-0.1	0.7	0.6	-0.2	0.3
Serious illness, injury or assault to yourself	0.3	0.3	1.9	0.6	-0.2	1.4	-0.0	0.5	-0.1	0.2	-0.1	-0.4	-0.7	0.3	0.6
High blood pressure	0.5	1.3	5.2	-0.8	0.2	2.3	-0.1	1.4	0.6	-0.3	-0.3	0.9	2.0	-0.3	-1.5
Hayfever, allergic rhinitis or eczema	0.7	1.6	4.9	-0.0	-0.5	-1.8	0.0	-1.5	-0.8	1.0	0.0	-1.4	-2.2	0.6	2.1
Multivitamins +/- minerals	1.0	1.3	3.2	1.0	-1.4	0.9	-1.4	-0.5	-1.1	-1.8	-1.2	-1.2	-0.2	-1.3	-0.7
Stomach or abdominal pain in last month	0.3	0.4	2.2	0.5	0.3	0.6	0.2	1.5	0.6	-0.3	0.0	0.9	0.1	-0.0	-0.5
Supplements: Glucosamine	0.3	0.3	0.8	0.9	-0.5	0.9	-0.5	-0.5	-0.6	0.1	-0.4	-0.9	0.2	-0.2	0.5
Diverticular disease/diverticulitis (self-reported)	3.9	4.6	10.6	2.4	-1.5	2.5	-2.0	-2.5	-1.6	-2.8	-1.9	-0.9	1.1	-1.9	-3.2
Medication: Atenolol	0.7	0.9	2.4	-0.1	0.8	0.0	0.8	1.1	0.7	1.6	0.9	0.3	0.0	1.4	1.5
Medication: Levothyroxine sodium	1.0	1.7	3.8	0.3	-1.9	0.3	-1.6	-0.2	-1.8	-1.0	-1.6	-1.9	-1.1	-1.3	0.0
Sitting height	0.7	5.2	50.6	7.1	0.2	2.2	-0.4	1.5	0.3	0.3	-0.2	1.1	1.4	-0.7	-0.3
Chronic bronchitis/emphysema (father)	0.7	0.9	4.6	-0.1	0.4	2.2	-0.2	0.1	0.2	-0.0	-0.2	0.8	1.9	-0.5	-0.9
High blood pressure (mother)	1.3	1.9	3.7	-0.3	1.6	0.8	1.4	0.8	1.9	1.3	1.4	1.9	1.7	1.5	0.2
Body mass index (BMI)	1.4	5.8	9.5	2.0	-3.1	2.9	-2.9	0.0	-2.4	-2.7	-3.1	-2.7	-0.3	-2.6	-1.9
Impedance of leg (left)	0.2	1.0	4.3	0.9	-0.4	0.5	-1.0	-2.1	-0.8	-0.9	-0.8	0.2	1.4	-1.0	-0.8
Leg predicted mass (left)	0.3	1.7	10.9	3.3	-0.6	1.8	-0.5	2.0	0.1	-0.3	-0.6	-0.1	-0.1	-0.8	-0.4
Trunk fat mass	1.7	7.1	16.9	4.1	-3.2	3.0	-3.1	0.1	-2.5	-2.6	-3.2	-2.8	0.1	-2.6	-1.5
Waist circumference	1.8	6.5	11.0	2.7	-3.3	2.5	-3.2	-0.2	-2.7	-2.8	-3.3	-2.8	-0.1	-2.8	-1.6
Number of incorrect matches in round	0.7	1.1	3.5	0.2	-0.6	1.9	-1.0	0.5	-0.5	-1.1	-1.1	-0.0	1.1	-1.1	-1.6
Past tobacco smoking	0.7	1.4	3.0	1.7	-0.8	1.7	-1.0	-0.6	-0.7	-1.2	-1.0	-0.4	0.7	-1.4	-1.7
Alcohol usually taken with meals	0.8	1.3	3.3	-0.3	1.8	-0.0	1.5	-0.1	1.4	1.3	1.6	1.4	0.4	1.3	0.1
Nervous feelings	0.2	0.5	2.3	-0.5	-0.0	-1.5	0.3	-0.3	0.2	0.4	0.3	0.1	-1.0	0.2	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.9	0.3	0.6	-0.4	0.6	2.0	0.5	1.1	0.9	0.5	-0.6	0.3	1.4
Hearing difficulty/problems with background noise	0.1	0.1	1.0	-0.1	0.0	-0.4	0.1	-1.0	0.0	0.1	0.1	-0.1	-0.0	0.4	-0.5
Hair/balding pattern: Pattern 2	1.2	1.6	3.9	0.5	-1.6	-0.5	-1.2	-0.8	-1.6	-1.0	-1.4	-2.0	-1.8	-0.9	0.5
Had menopause	1.5	1.9	3.4	1.5	-1.8	0.8	-1.8	-0.0	-1.7	-1.3	-1.7	-1.8	-0.5	-1.4	-0.2
Had other major operations	1.3	1.6	2.9	1.7	-1.3	1.2	-1.6	-0.6	-1.0	-1.3	-1.7	-0.4	0.4	-1.6	-1.2
Forced vital capacity (FVC)	0.5	1.8	6.5	2.6	-0.1	2.0	-0.6	-0.2	-0.0	-1.2	-0.6	0.7	1.8	-1.0	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	1.3	0.7	-0.8	-0.6	-0.8	-1.0	-1.0	-0.8	-0.7	-1.1	-1.1	-0.8	-0.6
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	4.6	1.1	-1.3	-1.3	-1.3	-1.5	-1.8	-0.8	-1.0	-1.6	-2.1	-1.2	0.6
Qualifications: None of the above	0.5	1.1	4.1	-2.0	0.8	0.8	0.9	0.8	1.3	0.2	0.6	0.9	1.5	0.8	-0.5
Financial difficulties in last 2 years	0.1	0.1	0.3	-0.0	0.1	0.5	0.3	0.6	0.4	0.2	0.2	0.4	0.5	0.5	0.1
Mouth/teeth dental problems	0.3	0.5	1.8	-0.2	-0.9	0.2	-0.9	-0.1	-0.8	-0.5	-1.0	-0.1	-0.4	-1.3	-0.5
Heart attack	0.2	0.3	1.3	0.9	0.3	1.1	0.3	0.3	0.3	-0.0	0.2	-0.0	0.2	0.7	0.4
Allergy	0.4	0.9	3.2	-0.0	0.9	0.8	0.5	1.4	1.1	0.0	0.6	1.4	1.8	0.2	-0.8
Pain all over the body in last month	0.1	0.2	0.5	-0.7	0.5	-0.2	0.2	-0.0	0.0	0.6	0.2	0.7	0.1	-0.0	0.4
Diabetes (self-reported)	0.5	0.8	2.8	-0.2	-0.9	-1.4	-0.3	0.2	-0.8	0.0	-0.3	-1.1	-1.7	0.3	1.4
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.4	-0.8	-0.0	-1.1	0.4	-0.8	-0.2	0.6	0.1	-0.3	-1.2	0.5	1.1
Medication: Ramipril	0.3	0.4	2.2	0.5	-0.2	1.5	-0.1	1.2	0.2	0.3	-0.3	0.4	0.9	-0.1	-0.4
Medication: Simvastatin	0.3	0.5	1.7	-0.8	0.5	0.9	0.5	0.2	0.5	-0.3	0.4	0.5	1.3	0.9	-1.0
Fluid intelligence score	0.5	1.0	4.9	0.5	-0.3	-1.6	-0.2	-1.4	-0.7	0.3	-0.1	-0.5	-2.2	-0.1	1.0
Illnesses of siblings	0.1	0.1	0.9	0.1	-0.0	-0.9	0.0	-0.0	-0.0	0.3	0.1	0.1	-0.3	-0.4	0.0
Neuroticism score	0.3	0.5	2.4	0.1	-0.1	-1.2	0.3	0.1	0.0	0.3	0.3	-0.2	-1.5	0.3	1.5
Weight	1.2	6.0	18.7	4.3	-2.7	3.0	-2.7	0.5	-2.0	-2.2	-2.8	-2.1	-0.1	-2.5	-1.5
Impedance of arm (right)	1.0	4.9	11.5	-2.0	2.1	-3.4	2.4	0.7	1.7	2.5	2.5	1.3	-0.5	2.7	2.8
Arm fat percentage (right)	0.6	2.4	5.7	1.2	-2.2	1.5	-1.8	0.7	-1.6	-1.5	-1.9	-2.4	-0.6	-1.2	-0.4
Trunk fat-free mass	0.3	1.9	14.3	3.8	-0.3	2.1	-0.5	1.2	-0.0	-0.4	-0.5	0.3	0.2	-1.0	-0.8
Hip circumference	0.4	1.5	7.5	2.7	-1.1	1.7	-1.0	1.3	-0.6	-0.9	-1.1	-1.0	-0.2	-0.8	-0.4
Time employed in main current job	0.5	0.5	2.6	0.6	0.1	0.9	-0.4	0.0	-0.2	-0.3	-0.4	0.2	1.6	-0.6	-1.3
Alcohol intake versus 10 years previously	0.9	1.3	2.6	-0.3	-1.2	1.5	-1.2	-0.9	-0.8	-1.6	-1.4	-0.6	0.2	-1.4	-1.6
Father’s age at death	0.6	0.8	3.6	0.2	0.6	-1.9	0.8	-0.2	0.2	0.9	0.9	-0.2	-1.0	1.2	1.0
Worrier / anxious feelings	0.5	0.9	1.8	0.9	-1.1	-0.6	-0.8	-1.1	-1.0	-0.4	-0.8	-1.3	-1.3	-0.5	0.8
Frequency of tiredness / lethargy in last 2 weeks	2.0	3.3	5.9	2.4	-2.3	1.2	-2.1	-0.7	-2.2	-2.0	-2.0	-2.2	-0.4	-2.0	-0.3
Falls in the last year	0.7	0.9	1.5	1.2	-1.1	1.2	-1.1	0.2	-1.1	-0.8	-0.9	-1.1	-0.1	-1.1	-0.4
Hair/balding pattern: Pattern 3	0.3	0.4	1.3	0.4	0.6	1.1	0.3	0.5	0.6	0.4	0.3	1.1	0.7	-0.1	-0.9
Number of live births	1.6	2.3	4.8	-0.7	1.4	-0.8	1.7	1.7	1.4	2.0	1.8	1.0	-0.9	1.8	2.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	2.7	1.6	-0.0	0.3	-0.1	-0.1	-0.0	-0.6	-0.2	0.1	0.0	-0.3	-0.6
Pulse rate	0.3	0.5	2.6	0.1	-0.3	1.4	-0.1	1.6	0.4	0.3	-0.2	0.2	1.0	0.1	0.0
Happiness	0.5	0.6	1.5	1.0	0.6	0.6	0.4	1.2	0.9	0.0	0.4	1.1	1.1	0.1	-0.9
Noisy workplace	0.1	0.1	0.3	-0.3	0.1	0.3	0.2	0.3	0.4	-0.1	0.2	0.1	0.6	0.3	0.1
Qualifications: A levels/AS levels or equivalent	0.6	1.4	2.5	1.3	1.6	-0.9	1.3	-0.0	0.9	1.6	1.5	1.5	0.6	1.1	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.9	-0.1	-0.3	0.2	0.0	-0.3	-0.1	-0.5	-0.0	-0.7	1.0	0.8	-0.4
Mouth/teeth dental problems: Dentures	0.1	0.2	0.5	-0.4	0.4	0.5	0.4	-0.6	0.4	-0.3	0.3	-0.1	0.7	0.7	-0.3
Asthma	0.1	0.1	0.4	-0.4	0.3	-0.1	0.2	0.4	0.2	-0.1	0.2	0.6	-0.2	0.0	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.3	-0.4	1.0	-1.0	0.7	0.9	0.4	1.0	0.9	1.2	-0.9	-0.1	0.7
Medication: Cholesterol lowering	2.0	3.1	5.8	-1.3	2.4	0.4	2.2	0.8	2.0	1.9	2.1	2.0	1.3	2.4	0.7
Depression (self-reported)	0.5	0.6	1.8	0.2	-0.8	0.1	-0.8	-0.0	-0.8	-0.8	-0.9	-0.3	-1.1	-1.3	-0.5
Medication: Lansoprazole	0.8	0.9	2.7	-0.9	-0.7	1.0	-0.8	-0.9	-0.6	-1.6	-0.9	-0.5	0.8	-0.4	-1.4
Prospective memory result	0.7	0.8	2.2	-0.3	-0.7	1.5	-0.8	0.5	-0.4	-1.3	-0.9	0.1	1.2	-0.8	-1.2
Lung cancer (father)	1.0	1.2	2.6	-1.0	0.7	-0.9	0.9	1.6	1.2	1.4	0.6	1.0	-0.4	1.0	1.5
Illnesses of mother	0.4	0.5	2.9	0.6	-0.4	-0.9	-0.5	-1.7	-0.9	-0.0	-0.3	-0.9	-0.6	-0.4	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	3.9	2.0	-0.9	0.5	-0.9	-0.3	-0.6	-1.1	-1.1	-0.4	0.0	-0.9	-0.7
Pulse wave Arterial Stiffness index	1.9	2.2	6.5	0.7	-1.5	-0.9	-1.4	-2.0	-1.8	-1.0	-1.6	-1.5	-2.5	-1.3	0.0
Impedance of arm (left)	0.7	3.2	10.8	-1.6	1.3	-3.3	1.6	0.6	1.1	1.9	1.7	0.7	-0.7	2.0	2.7
Arm fat mass (right)	0.9	3.8	6.6	2.6	-2.4	2.4	-2.2	0.7	-1.8	-1.9	-2.3	-2.3	-0.4	-1.8	-1.0
Trunk predicted mass	0.3	1.8	14.1	3.8	-0.2	2.0	-0.4	1.2	0.1	-0.3	-0.4	0.3	0.1	-0.9	-0.7
Standing height	0.3	2.9	32.1	5.7	0.3	0.7	-0.0	0.7	0.4	0.3	0.1	1.0	0.6	-0.5	0.3
Length of working week for main job	0.7	0.8	1.9	1.3	-0.8	1.4	-1.0	1.1	-0.6	-0.4	-1.0	-0.4	0.0	-1.3	-0.6
Exposure to tobacco smoke at home	0.3	0.3	2.8	-0.3	-0.1	-0.3	-0.0	0.6	-0.4	-0.0	-0.2	-0.2	-1.7	-0.3	0.2
Breastfed as a baby	0.8	1.0	3.7	0.1	-1.0	-0.2	-0.9	-0.8	-1.1	-0.9	-1.0	-1.3	-1.9	-0.8	-0.3
Tense / ‘highly strung’	0.7	1.1	4.1	-0.6	0.4	-1.0	0.4	1.9	0.3	1.6	0.6	0.6	-0.8	0.1	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	2.7	-0.0	-0.5	-0.6	-0.3	-0.1	-0.6	-0.4	-0.2	-0.6	-1.6	-0.7	0.6
Hair/balding pattern: Pattern 4	0.1	0.2	0.4	0.3	0.3	0.5	0.3	0.1	0.1	0.1	0.5	0.2	0.7	0.6	0.6
Birth weight of first child	2.8	5.1	12.5	3.5	-2.9	0.2	-2.7	-0.8	-2.5	-1.9	-2.8	-2.0	-1.8	-2.7	-0.3
Peak expiratory flow (PEF)	0.4	0.9	3.0	-0.5	0.3	-1.6	0.9	0.3	0.5	0.5	0.7	-0.3	-1.7	1.1	1.3
Pulse wave reflection index	0.8	0.9	5.3	-0.0	-0.4	-0.7	-0.5	-2.3	-0.8	-1.0	-0.6	-0.2	-1.2	-0.9	-0.6
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.6	0.9	-0.3	1.6	-0.4	0.7	-0.4	-0.5	-0.2	-0.2	0.9	-0.5	-0.6
Loud music exposure frequency	1.7	1.8	3.7	-0.8	1.4	-1.3	1.6	0.9	1.5	1.4	1.8	1.1	-0.2	1.9	1.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.9	0.4	1.2	-0.3	1.0	-0.7	0.9	0.6	1.0	1.4	0.1	1.0	-0.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.6	0.6	0.4	-0.5	0.6	1.0	0.7	0.8	0.5	0.2	0.2	1.3	1.0
Blood clot in the leg (DVT)	0.7	0.9	3.6	-0.2	-1.4	-0.1	-0.8	-0.3	-1.2	-0.6	-1.0	-1.9	-1.3	-0.4	0.4
Medication: Paracetamol	0.1	0.2	1.2	-1.1	-0.1	-0.1	-0.1	-0.4	-0.3	0.3	-0.2	0.1	-0.2	-0.0	0.7
Headache pain in last month	0.3	0.5	1.1	0.5	-0.8	-0.4	-0.7	0.6	-0.7	-0.2	-0.8	-0.6	-1.1	-0.8	0.7
Medication for cholesterol, blood pressure or diabetes	1.5	2.5	5.7	0.2	-1.9	-1.8	-1.3	-1.7	-1.6	-1.2	-1.4	-2.2	-2.4	-1.2	0.3
Glaucoma (self-reported)	0.7	0.8	2.1	0.1	0.8	-1.2	0.9	0.7	0.6	1.3	0.9	0.4	-0.7	1.1	1.4
Gout (self-reported)	0.4	0.6	1.8	0.8	0.6	0.7	0.2	-1.3	0.5	-0.1	0.1	0.9	1.1	0.2	-1.1
Hypothyroidism/myxoedema (self-reported)	1.3	2.6	5.0	0.7	-2.2	-0.2	-1.8	-0.8	-2.2	-1.4	-1.9	-2.2	-2.0	-1.7	0.0
Medication: Amlodipine	0.2	0.3	1.4	-0.8	-0.5	-1.2	-0.2	0.9	-0.1	-0.1	-0.4	-0.3	-0.6	0.0	0.4
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.0	0.1	-1.0	0.1	-0.8	0.3	-0.9	-0.7	-0.8	-0.9	-0.1	-0.5	-0.2
Birth weight	1.9	4.1	15.8	4.0	-1.9	3.2	-2.0	-0.4	-1.7	-1.2	-1.8	-1.7	0.3	-1.9	-1.0
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.8	0.1	-0.7	0.9	-0.5	0.1	-0.4	-0.3	-0.7	-0.4	-0.3	-0.2	0.2
High blood pressure (siblings)	1.0	1.4	3.9	1.0	-0.9	2.0	-1.2	-0.2	-0.9	-1.6	-1.3	-0.5	0.7	-1.1	-1.6
Forced vital capacity (FVC), Best measure	0.6	2.2	10.3	3.2	-0.8	1.9	-1.2	-0.5	-0.6	-1.4	-1.3	-0.1	1.4	-1.3	-1.5
Body fat percentage	1.8	7.2	11.4	3.1	-3.4	2.9	-3.3	-0.4	-2.7	-2.8	-3.4	-3.0	0.0	-2.6	-1.6
Leg fat percentage (right)	2.7	9.7	14.5	3.1	-3.6	3.8	-3.7	-1.3	-3.2	-3.5	-3.7	-3.1	0.2	-3.4	-2.5
Arm fat-free mass (right)	0.9	4.8	20.5	4.5	-1.8	3.3	-2.0	0.8	-1.1	-1.8	-2.1	-0.8	0.4	-2.3	-1.8
Exposure to tobacco smoke outside home	0.6	0.8	4.1	0.2	-0.1	2.0	-0.5	-0.4	-0.2	-0.8	-0.4	-0.0	0.9	-0.9	-1.5
Comparative body size at age 10	1.6	4.5	15.8	1.5	-1.1	2.9	-1.6	-1.6	-1.0	-2.6	-1.8	-0.5	2.5	-2.0	-4.0
Number of full brothers	2.3	2.9	5.1	0.2	-2.3	-0.4	-2.0	-1.1	-2.3	-2.1	-2.2	-1.8	-1.1	-2.2	-0.9
Worry too long after embarrassment	0.2	0.4	2.7	1.6	-0.4	-0.3	-0.3	-0.9	-0.6	-0.4	-0.2	-0.4	-0.2	-0.3	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.3	0.8	-0.8	0.4	-0.6	0.8	-0.6	-0.2	-0.5	-0.7	-0.9	-1.1	0.1
Wheeze or whistling in the chest in last year	0.7	1.3	4.1	0.1	-1.0	2.0	-1.0	0.8	-0.3	-1.6	-1.3	0.1	1.0	-1.1	-1.6
Number of children fathered	0.6	0.7	3.1	-0.3	0.8	0.2	0.6	0.6	0.9	0.8	0.7	0.8	1.8	0.9	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.5	0.6	-0.4	-0.7	-0.2	0.0	-0.2	0.0	-0.1	-0.4	-0.1	-0.1	0.6
Age at first live birth	0.5	1.0	2.5	-1.4	0.9	-0.7	0.9	1.6	0.9	0.9	0.9	1.0	0.6	1.0	0.4
Pulse wave peak to peak time	1.8	2.1	6.6	-0.2	1.4	1.0	1.3	1.9	1.7	1.0	1.5	1.5	2.6	1.2	-0.0
Health satisfaction	0.7	0.9	2.7	0.2	0.8	-0.2	1.0	0.7	0.9	1.5	1.1	0.5	0.2	1.3	1.6
Shortness of breath walking on level ground	0.9	1.1	5.5	-1.0	0.1	-1.0	0.4	1.6	0.3	1.1	0.5	-0.0	-1.0	0.6	2.3
Qualifications: College or University degree	0.2	0.7	3.6	0.9	0.1	-1.9	0.1	0.3	-0.3	1.0	0.4	-0.1	-1.4	-0.2	1.0
Eye problems/disorders: None of the above	0.3	0.4	2.8	-1.7	-0.2	-0.6	-0.0	0.8	0.1	0.4	-0.0	-0.2	-0.5	0.1	0.6
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.5	-0.2	0.3	-0.7	0.1	0.4	-0.1	0.2	0.2	0.4	-0.3	0.2	0.4
Emphysema/chronic bronchitis	0.3	0.3	1.3	-0.5	-0.4	0.9	-0.4	1.2	-0.0	-0.4	-0.4	-0.2	0.2	-0.4	-0.3
Medication for pain relief, constipation, heartburn	0.5	0.9	4.6	0.8	-0.4	1.5	-0.4	-0.7	0.1	-1.1	-0.5	-0.3	0.8	-0.6	-2.1
Neck or shoulder pain in last month	0.5	0.7	2.0	-0.1	-1.0	0.1	-0.8	-0.9	-1.1	0.0	-0.6	-1.2	-0.8	-0.4	1.4
Medication: Blood pressure	0.6	1.1	3.9	-0.8	1.1	1.0	0.7	2.0	1.0	1.1	0.7	1.3	1.2	0.6	0.1
Angina (self-reported)	0.6	0.8	1.5	-0.5	1.1	-0.9	1.1	0.0	0.7	1.1	1.2	0.8	-0.3	1.2	1.2
Migraine (self-reported)	0.2	0.3	0.8	-0.5	-0.1	-0.8	0.1	-0.9	-0.2	0.7	-0.0	-0.0	-0.6	0.1	0.7
Medication: Ibuprofen	0.7	0.9	2.7	-0.2	1.1	-0.4	1.0	1.6	0.7	1.0	1.1	1.5	-0.1	0.3	0.7
Medication: Allopurinol	0.7	0.9	3.4	0.0	0.8	0.5	0.3	-1.3	0.6	-0.1	0.2	1.3	1.8	0.1	-1.4
Medication: Omeprazole	2.4	2.8	6.2	0.8	-2.1	-0.3	-1.9	-1.2	-2.5	-0.5	-1.8	-2.5	-1.8	-1.8	1.3
Medication: Seretide 50 evohaler	1.3	1.5	3.0	1.2	-1.3	1.2	-1.4	-0.1	-1.4	-1.2	-1.3	-0.8	0.3	-1.7	-1.5
Mean time to correctly identify matches	0.9	1.8	3.8	0.8	-1.5	-0.2	-1.6	-1.1	-1.9	-1.6	-1.5	-1.4	-0.9	-1.6	-0.8
Heart disease (mother)	0.5	0.6	1.9	-0.4	-1.1	-0.2	-0.5	0.2	-0.7	-1.1	-0.6	-1.4	-0.9	0.1	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	3.0	-1.3	0.8	0.9	0.9	0.7	1.3	-0.1	0.8	0.7	1.7	1.1	-0.7
Whole body fat mass	1.8	7.3	14.4	3.8	-3.2	3.3	-3.2	-0.1	-2.5	-2.8	-3.2	-2.7	0.1	-2.7	-1.8
Leg fat mass (right)	2.1	8.2	14.4	3.8	-3.2	3.8	-3.3	-0.4	-2.7	-3.0	-3.3	-2.7	0.4	-3.0	-2.2
Arm predicted mass (right)	0.9	4.5	20.4	4.5	-1.6	3.3	-1.9	0.6	-1.0	-1.7	-2.0	-0.6	0.6	-2.1	-1.8
Pulse rate, automated reading	0.9	2.9	9.6	1.1	-1.4	3.1	-1.7	-1.6	-1.4	-1.3	-1.8	-0.8	1.1	-1.8	-1.9
Alcohol intake frequency.	1.4	3.2	5.6	1.0	-2.1	0.8	-2.2	-1.3	-2.2	-2.2	-2.2	-1.9	-1.2	-2.4	-0.9
Comparative height size at age 10	0.3	1.7	18.2	4.3	-0.3	0.2	-0.4	0.7	-0.2	0.3	-0.3	-0.1	-0.1	-0.6	0.7
Number of full sisters	0.4	0.5	1.3	-0.9	-0.7	-0.6	-0.1	1.0	-0.2	-0.2	-0.4	-0.8	-1.0	0.4	1.1
Suffer from ‘nerves’	1.3	2.0	7.8	-1.9	0.1	-2.8	0.4	0.4	-0.1	1.1	0.5	-0.1	-2.0	0.1	2.6
Overall health rating	0.9	1.9	3.4	1.2	-1.8	0.4	-1.8	-0.9	-1.8	-1.0	-1.7	-1.5	-1.3	-1.5	0.4
Chest pain or discomfort	0.7	1.0	2.7	1.0	-1.1	-0.6	-1.1	-0.7	-1.6	-0.0	-0.7	-1.6	-0.7	-1.0	0.9
Had major operations	0.3	0.3	0.9	0.9	-0.4	-0.3	-0.5	-0.2	-0.8	0.1	-0.3	-1.0	-0.8	-0.2	0.5
Age at last live birth	2.3	3.3	5.5	-2.3	1.9	-1.1	2.2	2.0	2.0	1.9	2.1	1.5	0.4	2.2	1.4
Family relationship satisfaction	0.2	0.2	0.8	0.9	0.5	-0.2	0.5	0.6	0.4	-0.1	0.7	0.3	-0.2	0.3	-0.1
Leg pain on walking	0.2	0.3	1.4	-1.2	-0.1	-0.8	0.1	1.0	-0.0	-0.1	0.0	0.1	-0.4	-0.0	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.4	0.3	-0.2	0.6	-0.2	0.4	-0.0	0.2	-0.1	-0.2	0.6	-0.4	0.1
Commuting to job workplace: Car/motor vehicle	1.8	2.1	5.6	-1.0	1.9	-0.0	1.5	1.2	1.9	1.0	1.6	2.4	1.6	1.0	-0.4
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.5	0.5	0.5	-0.4	0.3	0.1	0.3	0.7	0.5	0.5	-0.7	-0.0	0.6
Medication: Aspirin	0.4	0.5	1.7	0.1	0.3	-1.0	0.4	1.3	0.2	0.7	0.4	0.2	-0.5	0.7	1.3
Supplements: Vitamin C	0.5	0.6	2.0	1.4	-0.0	-0.2	-0.3	0.3	-0.8	0.5	0.0	-0.7	-1.4	-0.3	1.3
Knee pain experienced in last month	0.3	0.5	2.6	0.3	-0.5	1.1	-0.5	-0.8	-0.1	-0.3	-0.5	0.0	1.6	-0.5	-0.0
Hypertension (Self-reported)	0.5	1.5	5.5	-0.6	0.3	2.3	-0.2	1.4	0.6	-0.3	-0.3	1.0	2.3	-0.4	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.4	-0.4	-0.6	0.1	-0.6	0.1	-0.6	-0.6	-0.6	-0.5	0.4	-0.6	-0.4
Illnesses of father: Heart disease	0.5	0.6	2.5	0.8	0.8	0.9	0.7	1.6	0.9	0.0	0.7	0.5	0.3	1.0	-0.0
Illnesses of siblings: Diabetes	0.2	0.3	0.6	-0.2	0.7	0.5	0.7	-0.2	0.4	-0.1	0.8	0.2	-0.6	0.7	0.5
Smoking status: Previous	1.1	1.6	2.7	-1.4	1.3	-0.8	1.4	1.2	1.4	1.3	1.4	1.3	0.5	1.6	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	3.9	2.0	0.2	0.2	0.2	1.0	0.7	0.6	0.2	0.8	1.1	0.3	0.4
Whole body fat-free mass	0.4	2.1	15.0	3.9	-0.6	2.2	-0.7	1.5	-0.1	-0.5	-0.7	0.0	0.1	-1.1	-0.8
Leg fat-free mass (right)	0.3	1.5	9.5	3.1	-0.7	1.6	-0.6	2.0	0.0	-0.4	-0.7	-0.3	-0.2	-0.7	-0.3
Arm fat percentage (left)	0.9	3.8	8.0	1.7	-2.8	1.7	-2.4	0.5	-2.1	-1.9	-2.5	-2.8	-0.7	-1.7	-0.6
Average weekly red wine intake	0.2	0.3	0.9	0.7	-0.1	-0.0	-0.3	-0.9	0.0	-0.3	-0.2	0.2	0.9	-0.1	-0.8
Handedness (chirality/laterality): Left-handed	1.3	1.6	3.8	0.5	1.2	-0.8	1.0	1.9	1.1	1.9	1.1	1.3	0.1	0.8	1.9
Mood swings	0.1	0.2	0.4	-0.6	0.4	0.1	0.6	0.0	0.6	-0.0	0.5	0.6	-0.1	0.4	0.3
Loneliness, isolation	0.7	1.0	2.6	1.6	-1.0	0.1	-1.0	-0.5	-1.2	-1.0	-0.9	-0.9	-1.2	-1.3	0.2
Long-standing illness, disability or infirmity	0.5	0.8	1.5	1.1	-1.1	0.3	-1.0	-1.1	-1.2	-0.7	-0.9	-1.0	-0.6	-0.8	0.1
Ever had bowel cancer screening	0.6	0.7	2.6	1.6	-0.8	1.1	-0.8	0.4	-0.4	-0.8	-0.9	-0.5	0.5	-0.9	-0.8
Diabetes diagnosed by doctor	0.1	0.2	0.7	-0.0	-0.5	-0.7	-0.2	0.1	-0.4	-0.2	-0.2	-0.6	-0.8	0.3	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.1	-0.7	0.5	0.1	0.5	0.3	0.3	0.7	0.5	-0.1	-0.1	0.8	1.0
Friendships satisfaction	0.7	0.9	1.6	-0.1	1.0	-1.2	1.2	1.0	1.2	0.9	1.2	1.0	-0.4	1.1	0.4
Qualifications: nursing, teaching	0.3	0.5	1.8	0.6	-0.4	0.3	-0.8	-1.4	-0.7	-0.8	-0.7	-0.2	-0.1	-0.7	-1.1
Commuting to job workplace: Walk	3.5	3.7	6.0	2.1	-2.5	0.5	-2.3	-1.4	-2.2	-2.2	-2.4	-2.0	-1.6	-2.0	-1.0
Eye problems/disorders: Cataract	2.2	2.5	5.7	2.4	-1.5	1.0	-1.6	-1.2	-1.6	-2.1	-1.7	-1.2	-0.0	-1.7	-1.8
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	2.2	-0.6	1.3	0.0	1.3	1.4	1.3	1.4	1.5	0.9	0.4	0.9	0.6
Medication for cholesterol	0.6	0.9	1.8	-1.0	1.3	-1.2	1.0	-1.3	0.6	0.8	1.0	1.1	0.1	0.6	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	3.8	-0.7	-0.3	-1.4	0.3	0.7	0.2	1.1	0.3	-0.7	-0.7	0.9	2.0
Back pain experienced in last month	1.7	2.5	4.9	1.8	-1.4	1.9	-1.5	-2.2	-1.5	-1.9	-1.4	-1.5	0.4	-1.4	-1.5
Mineral and other dietary supplements	0.3	0.5	1.4	-0.5	0.8	-0.0	0.8	1.0	0.8	0.5	0.6	1.2	0.5	0.3	-0.2
Breast cancer (self-reported)	1.3	1.6	3.1	0.9	-1.5	0.5	-1.6	-0.9	-1.4	-1.8	-1.5	-1.3	-0.1	-1.6	-1.0
Asthma (self-reported)	0.0	0.1	0.3	-0.4	0.1	-0.2	0.1	0.3	0.0	-0.3	-0.0	0.4	-0.2	-0.1	-0.6
Osteoporosis (self-reported)	0.4	0.5	1.5	-0.7	-0.7	-0.7	-0.4	-0.8	-0.7	-0.4	-0.5	-1.2	-1.2	-0.1	0.6
Osteoarthritis (self-reported)	0.2	0.3	1.8	0.3	-0.2	1.3	-0.2	-0.3	0.1	0.1	-0.2	-0.2	0.8	0.5	0.3
Medication: Aspirin	0.6	0.7	2.5	-0.3	0.3	-1.3	0.6	1.2	0.3	0.8	0.6	0.2	-0.7	1.1	1.6
Medication: Gliclazide	0.3	0.3	0.6	0.7	-0.8	-0.4	-0.8	-0.5	-0.8	-0.4	-0.7	-0.6	-0.1	-0.6	0.2
Illnesses of father: None of the above (group 1)	2.1	2.7	4.6	-0.6	-2.1	-1.5	-1.8	-0.8	-2.0	-1.0	-1.9	-2.0	-2.0	-2.0	0.3
Smoking status: Current	0.3	0.5	0.9	-0.7	-1.0	-0.2	-0.9	-0.4	-0.9	-0.8	-1.0	-0.7	-0.1	-0.8	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	1.1	1.0	0.5	1.0	0.2	-0.1	0.5	-0.1	0.2	0.7	0.8	0.2	-0.6
Whole body water mass	0.4	2.2	15.1	3.9	-0.6	2.3	-0.7	1.6	-0.1	-0.5	-0.7	0.0	0.1	-1.1	-0.8
Leg predicted mass (right)	0.3	1.6	9.9	3.1	-0.8	1.7	-0.6	1.9	-0.1	-0.4	-0.8	-0.4	-0.2	-0.8	-0.3
Arm fat mass (left)	1.2	5.0	8.2	2.8	-2.9	2.5	-2.6	0.5	-2.1	-2.3	-2.8	-2.5	-0.3	-2.1	-1.3
Number of self-reported non-cancer illnesses	1.2	2.1	3.5	0.8	-1.2	1.9	-1.7	-1.6	-1.6	-1.6	-1.7	-0.6	0.4	-1.8	-1.5
Average weekly champagne plus white wine intake	3.8	5.2	9.6	-1.8	3.1	-0.5	2.9	0.9	3.0	2.3	3.0	2.6	1.6	2.7	0.2
Miserableness	1.3	2.2	4.2	-0.4	1.7	0.0	1.9	1.3	2.1	1.4	1.9	1.6	0.4	1.9	1.3
Guilty feelings	0.6	0.9	4.6	-0.2	-0.3	-1.3	0.3	0.6	0.1	0.8	0.3	-0.7	-1.5	0.6	2.1
Wears glasses or contact lenses	1.0	1.2	2.9	-0.1	-0.9	0.4	-1.3	-1.7	-1.6	-0.9	-1.0	-1.4	-0.7	-1.2	-0.6
Ever taken oral contraceptive pill	0.8	0.9	2.1	-1.3	1.2	-0.5	0.8	-0.1	0.9	0.7	1.0	1.5	1.3	0.4	-0.4
Hearing aid user	0.7	0.8	1.8	-1.2	0.9	-0.8	1.1	0.3	1.1	0.7	0.9	0.9	0.6	1.4	0.1
Mother’s age at death	0.1	0.2	0.5	-0.0	0.7	0.0	0.4	-0.5	0.0	0.5	0.6	0.1	0.4	0.5	0.5
Financial situation satisfaction	0.5	0.6	1.7	0.5	0.6	0.8	0.4	1.1	0.7	-0.3	0.3	1.2	1.1	-0.1	-1.3
Tinnitus: Yes, now most or all of the time	3.0	3.4	8.4	-1.2	1.7	-1.5	2.0	1.8	1.5	2.3	2.2	1.1	-1.0	2.2	2.9
Commuting to job workplace: Public transport	0.6	0.7	2.9	0.2	-0.6	-1.4	-0.3	0.1	-0.8	0.6	-0.3	-0.8	-1.7	-0.1	1.1
Eye problems/disorders: Glaucoma	0.6	0.7	2.6	0.3	0.7	-1.0	0.8	0.4	0.5	1.0	0.8	0.3	-0.8	0.8	1.6
Medication: Blood pressure	0.3	0.6	2.0	-0.0	-0.6	1.4	-0.5	1.1	0.1	-0.8	-0.7	-0.2	0.9	-0.3	-0.8
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.5	-0.5	0.1	0.4	0.1	-0.7	-0.1	-0.4	0.3	-0.2	0.0	-0.0	-0.3
Supplements: Fish oil (including cod liver oil)	1.5	1.9	2.7	1.3	-1.5	1.1	-1.7	-1.4	-1.6	-1.6	-1.5	-1.6	-0.4	-1.6	-1.0
High cholesterol (Self-reported)	0.7	1.2	4.1	-0.8	1.0	1.6	0.6	0.4	0.8	-0.2	0.6	1.4	2.0	0.6	-1.5
Medication: Bendroflumethiazide	1.2	1.9	10.0	-0.5	1.3	1.2	1.2	3.2	1.4	1.2	1.2	1.3	0.4	0.9	0.5
Medication: Paracetamol	0.3	0.4	1.6	-1.3	0.3	-0.0	0.5	0.3	0.4	0.8	0.5	0.4	0.6	0.8	0.9
Medication: Lisinopril	0.3	0.4	0.9	0.7	0.9	0.6	0.5	-0.3	0.5	0.2	0.8	0.8	0.9	0.5	-0.5
Medication: Atorvastatin	0.1	0.1	1.0	1.0	0.1	0.4	-0.2	0.1	-0.1	-0.0	-0.0	0.4	0.2	-0.3	-0.1
Illnesses of father: High blood pressure	0.5	0.6	1.6	0.9	0.7	0.9	0.4	0.1	0.8	-0.1	0.5	1.2	1.1	0.2	-1.2
Alcohol drinker status: Never	2.5	3.0	5.1	1.4	-2.1	1.0	-2.0	-0.9	-2.0	-2.1	-2.2	-1.7	-0.4	-2.1	-1.5
Ever smoked	0.8	1.5	5.6	-1.3	-0.2	-2.3	0.3	-0.5	-0.3	1.1	0.4	-0.9	-1.3	1.0	2.4
Basal metabolic rate	0.5	2.9	17.0	4.1	-1.1	2.5	-1.2	1.4	-0.5	-0.9	-1.2	-0.5	0.1	-1.5	-1.0
Leg fat percentage (left)	3.1	11.3	16.7	3.1	-4.0	3.9	-4.1	-1.7	-3.4	-3.9	-4.1	-3.5	0.3	-3.5	-2.7
Arm fat-free mass (left)	0.6	3.3	18.1	4.2	-1.1	3.0	-1.3	1.0	-0.5	-1.2	-1.3	-0.2	0.5	-1.6	-1.5
Number of operations (self-reported)	2.6	3.9	7.5	2.7	-2.0	1.4	-2.3	-2.4	-2.2	-1.7	-2.2	-1.6	-0.4	-2.4	-1.1
Average weekly beer plus cider intake	0.8	1.1	6.5	-2.5	0.7	-0.2	0.9	0.8	1.0	-0.0	0.7	1.0	1.3	0.7	-0.4
Irritability	0.8	1.3	5.4	0.5	-0.9	-1.4	-0.6	-0.5	-1.2	-0.0	-0.5	-1.5	-2.3	-0.6	1.5
Risk taking	1.3	2.0	6.0	-1.8	0.5	-2.1	0.9	1.2	0.3	1.3	0.9	0.1	-2.5	0.5	2.1
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.9	0.2	0.9	-0.2	0.8	-0.1	0.7	0.3	0.9	0.7	0.1	0.6	-0.1
Fractured/broken bones in last 5 years	0.6	0.8	2.8	0.4	0.3	-1.1	0.6	1.2	0.4	0.8	0.6	0.1	-1.7	0.4	1.3
Age started oral contraceptive pill	0.1	0.1	0.4	-0.0	-0.3	0.7	-0.3	0.6	-0.3	0.2	-0.4	-0.3	-0.0	-0.3	0.0
Diastolic blood pressure, automated reading	0.2	0.7	5.6	-0.3	0.2	2.4	-0.1	-0.0	0.2	-0.4	-0.2	0.6	0.6	-0.3	-1.5
Ever depressed for a whole week	0.4	0.5	1.4	0.9	-0.4	-0.1	-0.6	-1.0	-1.1	-0.3	-0.3	-0.8	-1.2	-0.9	-0.1
Unable to work because of sickness or disability	0.1	0.1	0.4	-0.1	-0.3	-0.3	-0.4	-0.4	-0.5	-0.1	-0.2	-0.3	-0.6	-0.5	0.3
Commuting to job workplace: Cycle	3.5	4.3	7.7	0.7	-2.5	-0.4	-2.5	-2.8	-2.6	-2.2	-2.4	-2.2	-0.9	-2.4	-1.3
Myopia	0.3	0.4	1.3	-0.5	-0.6	0.1	-0.7	-0.2	-0.6	-1.0	-0.6	-0.4	0.2	-0.8	-1.1
Vascular/heart problems diagnosed by doctor	0.5	1.3	5.5	0.3	-0.4	-2.4	-0.1	-1.4	-0.8	0.0	0.0	-0.9	-2.1	-0.1	1.1
Cholesterol lowering medication	1.0	1.5	4.1	0.6	-1.5	1.5	-1.4	0.3	-0.9	-2.0	-1.4	-0.8	0.6	-1.0	-1.6
Medication: Omeprazole (e.g. Zanprol)	4.0	4.9	10.7	1.0	-2.9	-0.2	-2.7	-1.8	-3.3	-1.4	-2.5	-3.3	-1.8	-2.3	0.8
Pain experienced in last month	0.4	0.7	2.0	-1.1	0.7	-0.6	0.9	1.4	1.1	0.5	0.8	0.4	-0.1	1.1	0.1
Supplements: Calcium	0.2	0.2	1.5	1.2	0.3	0.4	-0.1	-0.4	0.1	0.3	0.1	0.3	0.7	-0.2	0.3
Basal cell carcinoma (self-reported)	1.0	1.1	2.7	0.8	-1.3	-0.2	-1.0	-0.7	-1.5	-0.5	-0.9	-1.6	-1.6	-0.9	0.6
Heart attack/myocardial infarction (self-reported)	0.2	0.2	1.0	0.7	0.2	1.0	0.2	0.0	0.2	-0.0	0.2	-0.2	0.0	0.7	0.4
Deep venous thrombosis (DVT) (self-reported)	0.9	1.2	3.6	0.1	-1.6	0.4	-1.1	-0.3	-1.4	-1.0	-1.3	-1.9	-1.1	-0.7	0.0
Heart disease (siblings)	0.1	0.1	0.4	-0.2	0.0	0.6	0.0	-0.3	-0.0	-0.6	0.0	-0.2	0.1	0.3	-0.4
Alcohol drinker status: Previous	0.3	0.3	1.7	0.0	-0.4	1.3	-0.4	-0.7	-0.4	-0.3	-0.2	-0.8	0.4	-0.1	0.4
Pack years of smoking	2.2	3.2	7.0	0.9	-1.6	2.5	-2.0	-0.3	-1.5	-2.2	-2.1	-0.8	0.7	-2.6	-2.3
Impedance of whole body	0.1	0.4	2.2	-0.2	0.3	-1.5	0.3	-0.9	0.1	0.4	0.4	0.4	0.5	0.5	0.9
Leg fat mass (left)	2.3	8.9	15.4	3.7	-3.3	3.9	-3.4	-0.5	-2.7	-3.3	-3.5	-2.8	0.5	-3.1	-2.4
Arm predicted mass (left)	0.8	4.0	20.3	4.5	-1.1	3.4	-1.4	1.0	-0.6	-1.3	-1.5	-0.2	0.6	-1.8	-1.8