Hub : Genes

TMEM150C

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1030	0.0450	1.0e-02	-0.002	0.002	0.021	0.009	-0.002	9.2e-01	1.8e-01	1.1e-03	2.2e-02	7.8e-01
2	GTEx	Brain Caudate basal ganglia	0.3110	0.0860	3.0e-04	0.060	NA	0.031	NA	0.017	8.3e-03	NA	4.4e-02	NA	1.0e-01
3	GTEx	Brain Cortex	0.2050	0.0990	6.7e-03	-0.002	NA	0.060	NA	0.016	3.6e-01	NA	9.7e-03	NA	1.2e-01
4	GTEx	Esophagus Mucosa	0.2410	0.0690	2.5e-04	0.130	NA	0.139	NA	0.135	5.3e-09	NA	1.4e-09	NA	2.7e-09
5	GTEx	Esophagus Muscularis	0.1690	0.0530	4.4e-04	0.011	NA	0.014	NA	0.023	7.0e-02	NA	4.8e-02	NA	1.4e-02
6	GTEx	Heart Left Ventricle	0.2124	0.0573	3.9e-05	0.112	NA	0.057	NA	0.073	1.5e-06	NA	5.7e-04	NA	1.0e-04
7	GTEx	Lung	0.1416	0.0456	2.1e-04	0.009	NA	0.049	NA	0.026	6.3e-02	NA	1.3e-04	NA	3.9e-03
8	GTEx	Muscle Skeletal	0.1649	0.0422	8.3e-07	0.021	NA	0.050	NA	0.058	3.6e-03	NA	1.2e-05	NA	2.2e-06
9	GTEx	Pituitary	0.3900	0.1100	9.4e-04	0.103	NA	0.091	NA	0.147	1.5e-03	NA	2.8e-03	NA	1.6e-04
10	GTEx	Thyroid	0.1190	0.0360	1.7e-04	0.047	NA	0.072	NA	0.083	1.6e-04	NA	3.5e-06	NA	6.6e-07
11	METSIM	Adipose	0.0506	0.0187	1.2e-04	0.003	0.017	0.006	0.016	0.005	1.1e-01	9.9e-04	3.4e-02	1.7e-03	4.4e-02
12	ROSMAP	Brain Pre-frontal Cortex	0.1505	0.0371	3.4e-08	0.100	0.066	0.108	0.089	0.106	8.5e-13	6.8e-09	9.1e-14	1.8e-11	1.6e-13
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.1035	0.0287	1.6e-09	0.068	0.093	0.094	NA	0.088	3.8e-08	1.2e-10	9.4e-11	NA	4.1e-10
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1170	0.0490	1.8e-03	0.121	0.058	0.091	NA	0.090	2.1e-07	2.9e-04	6.9e-06	NA	7.6e-06
15	TCGA	Brain Lower Grade Glioma	0.0756	0.0297	7.7e-04	0.039	0.033	0.049	NA	0.038	2.7e-05	9.6e-05	2.6e-06	NA	3.1e-05
16	TCGA	Prostate Adenocarcinoma	0.0987	0.0364	1.6e-04	0.039	0.032	0.016	NA	0.024	6.2e-05	2.4e-04	7.7e-03	NA	1.5e-03
17	TCGA	Thyroid Carcinoma	0.1150	0.0390	4.3e-06	0.069	0.076	0.079	NA	0.079	2.8e-07	7.2e-08	4.0e-08	NA	3.8e-08

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.4	0.7	3.1	0.1	0.9	-1.4	1.8	-0.4	0.1	-1.3	-0.2	0.5	0.6	-1.1	-0.3	0.1	-0.4	-0.9	-0.4	1.1
Bipolar Disorder or Schizophrenia	0.6	1.4	7.1	-0.8	-0.0	-2.7	2.1	-1.0	-0.9	-1.1	-1.1	-1.3	0.7	-0.8	-0.7	-0.2	-1.4	-1.3	0.2	0.8
Depressed Affect (Nagel 2018)	0.8	1.7	4.5	-1.9	0.5	-0.0	1.2	-2.0	-2.1	-0.0	-1.8	-0.3	-0.8	-2.1	-0.3	-1.9	-0.6	-0.8	-1.1	-0.9
Depression (Nagel 2018)	0.3	0.4	2.3	-0.3	1.2	0.9	0.2	0.1	-0.2	1.1	-0.3	-0.0	-0.0	0.4	-0.8	-0.3	-0.3	-0.6	-1.5	0.3
Intelligence (Savage-Jansen 2018)	0.3	1.0	3.6	1.6	0.5	1.7	-0.9	-0.7	-0.6	-0.0	-0.5	-1.4	-0.8	-0.1	1.9	0.4	0.7	0.9	1.1	-0.5
Neuroticism (Nagel 2018)	0.9	2.0	6.5	-2.1	0.5	0.4	1.1	-1.9	-2.3	0.4	-2.5	-0.6	-0.7	-1.5	-0.2	-2.0	-1.4	-1.6	-1.1	-0.4
Schizophrenia (2018)	0.7	1.4	5.8	-1.6	-0.8	-2.4	1.3	-1.1	-1.3	-0.4	-1.2	-2.1	0.3	-0.2	-0.6	-0.1	-1.5	-1.0	0.9	0.2
Schizophrenia vs Biploar Disorder	0.5	0.7	2.6	-1.6	0.3	-1.1	0.8	0.3	-0.3	0.7	-0.5	-1.5	1.2	1.1	0.3	-0.8	0.0	-0.2	1.0	0.0
Worry (Nagel 2018)	0.3	0.7	3.4	-1.9	0.0	0.1	0.0	-0.6	-0.8	0.3	-1.3	0.3	0.3	-0.2	-0.0	-0.3	-0.8	-1.8	-1.0	0.9
Alzheimer’s Disease (in mother)	1.0	1.2	5.0	-0.5	2.0	1.2	-0.0	-0.3	-0.3	1.4	-1.2	-0.4	0.5	-0.5	0.2	0.2	-1.5	-2.2	-1.4	0.4
Alzheimer’s Disease (in father)	0.6	0.7	4.7	-0.6	-0.8	1.2	-0.4	0.2	0.5	-2.2	0.3	0.8	-0.2	1.3	-0.9	-0.1	-0.1	0.2	-0.8	-0.4
Alzheimer’s Disease (including proxy)	0.4	0.6	1.4	-1.0	1.0	1.2	0.2	-0.8	0.0	-0.6	-1.1	0.4	-0.0	-0.4	-0.7	0.1	-1.2	-1.2	-0.7	0.0
Crohns Disease (2017)	0.3	0.7	3.8	-1.6	0.4	-0.6	2.0	0.2	0.0	0.7	-0.4	0.3	0.7	0.1	-1.6	0.1	-0.8	-0.4	0.2	0.3
Irritable Bowel Disease (IBD)	0.5	1.1	5.1	-0.9	-0.3	-1.5	2.3	0.8	1.0	-0.1	0.5	1.2	1.5	0.1	-1.6	0.8	-0.4	-0.1	0.1	1.1
Ulcerative Colitis (UC)	0.8	1.5	3.8	0.0	-0.6	-1.7	1.9	1.2	1.6	-0.5	1.3	1.7	1.9	0.2	-0.8	1.4	0.2	-0.1	-0.1	1.9
Major Depression (MDD)	2.1	2.6	11.2	-1.6	1.5	-0.3	1.4	0.8	0.9	1.0	-0.8	-0.6	2.1	-0.3	-0.3	0.3	-2.2	-3.4	-3.0	1.8
Reaction Time	1.6	3.0	7.8	-1.7	-2.8	-1.9	-2.2	1.6	1.8	-1.5	2.0	1.9	0.5	1.4	-1.0	1.4	1.1	1.7	2.3	1.2
Verbal and Numeric Reasoning (VNR)	0.6	1.3	7.5	2.5	0.7	1.9	-1.0	-0.5	0.2	-0.4	0.2	0.1	-0.2	-0.8	2.7	1.1	0.9	0.5	0.5	0.4
Breast Cancer	1.2	3.0	17.2	-0.3	-3.5	-1.7	-2.8	0.2	-0.7	0.2	1.3	-0.8	-0.9	0.6	-4.2	0.7	2.1	0.9	-0.7	-0.5
Ovarian Cancer	0.6	0.8	5.9	0.8	0.1	0.1	0.4	-0.7	-0.3	-2.4	-0.0	0.8	-0.5	-1.5	1.1	-0.0	0.9	0.5	-0.2	-0.2
Prostate Cancer	0.9	1.3	3.2	-1.4	-1.5	-1.8	-0.3	-0.0	-0.7	1.3	-0.6	-1.2	-0.7	1.4	-1.4	-1.2	-0.4	0.8	1.6	-0.7
Age at First Birth	0.6	0.9	3.9	1.8	-0.8	0.0	-2.0	-0.3	-1.1	-0.3	-0.5	-0.6	-1.7	0.5	-0.9	0.6	0.5	0.1	-0.7	-0.5
Bipolar Disorder (2011)	0.3	0.3	1.3	0.5	0.0	-1.1	0.6	-0.6	-0.4	1.0	0.0	0.3	-0.3	1.2	-0.8	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.2	0.2	0.8	-0.7	-0.8	0.3	-0.2	0.1	0.2	-0.6	0.4	-0.1	-0.1	0.2	-0.5	0.3	0.5	0.8	0.9	0.2
Coronary Artery Disease (CAD)	1.6	1.9	7.1	-0.9	0.7	-2.7	-0.4	-1.0	-1.2	0.6	-1.9	-1.8	-0.7	-0.8	0.0	-1.4	-2.3	0.0	2.4	-0.7
Crohns Disease (2012)	0.5	0.8	3.7	-0.8	0.9	-1.9	1.9	0.2	-0.2	1.5	-0.3	0.2	0.5	0.5	-0.7	0.5	-0.3	0.6	0.7	0.4
Mean Putamen Volume	1.3	1.5	4.0	1.5	0.8	0.7	1.7	1.0	1.1	0.2	1.4	1.2	1.3	1.0	1.6	2.0	1.0	-0.2	0.1	1.9
Fasting Glucose	0.5	0.6	2.9	-1.0	-1.3	-0.7	0.0	1.1	0.3	1.7	0.6	-1.0	0.0	0.9	-0.9	0.2	0.1	0.2	-0.2	-0.3
HbA1C	1.4	1.5	5.2	-0.3	0.8	-1.9	1.6	1.4	1.2	0.3	0.9	-0.1	2.2	-0.1	0.5	1.3	-0.2	-2.3	0.5	1.6
HDL Cholesterol	0.6	1.0	3.7	1.6	-0.6	-0.5	1.5	0.8	0.9	0.1	1.2	0.3	1.0	0.5	1.9	1.5	0.6	-0.0	0.2	1.3
LDL Cholesterol	1.0	1.6	8.4	0.7	1.6	0.2	0.6	-1.7	-1.4	-1.7	-1.2	-0.2	-1.0	-2.9	1.2	-0.8	0.1	0.3	1.4	-1.3
Lupus	0.3	0.4	1.3	-0.5	-0.9	-1.1	-0.4	0.2	-0.1	0.7	0.0	-0.2	0.2	0.5	-1.1	-0.1	0.2	-0.9	-1.0	0.2
Neuroticism (2016)	0.6	0.9	2.8	-1.4	1.1	1.1	0.2	-1.0	-0.8	0.6	-1.4	0.3	-0.1	-0.6	1.7	-0.9	-1.3	-0.6	-0.5	-0.3
Primary Biliary Cirrhosis	0.7	1.1	3.9	-0.5	1.9	-1.8	2.0	0.7	1.3	-0.2	0.7	0.3	1.4	-0.0	0.5	-0.5	-0.5	-0.4	0.0	0.9
Rheumatoid Arthritis	0.4	0.5	2.0	-0.2	1.0	-0.6	-0.1	-0.8	0.2	-1.4	0.3	0.9	-0.1	-0.9	0.6	0.6	0.5	1.2	0.6	0.4
Schizophrenia (2014)	0.5	1.2	6.5	-1.7	-0.3	-2.6	2.3	-0.9	-0.5	-1.1	-0.2	-1.0	0.9	-0.0	-0.7	0.2	-0.6	-0.4	0.7	0.3
Triglycerides	0.8	1.3	5.7	-0.2	-0.4	-0.6	-0.6	-1.2	-1.4	-1.1	-0.7	0.3	-1.6	-1.3	-1.7	-1.1	0.6	1.2	0.1	-2.4
Type 2 Diabetes (T2D) (2012)	0.8	1.0	5.4	2.3	0.9	0.7	0.3	0.4	-0.2	1.4	-0.5	-1.5	-0.2	-0.7	1.8	-1.0	-0.1	0.1	-0.2	-0.8
Ulcerative Colitis	0.5	0.7	5.0	-1.1	-0.9	-2.2	0.3	0.6	0.8	0.2	0.8	0.4	1.1	0.5	-0.1	0.7	-0.1	0.2	0.8	0.7
Blood Eosinophil Count	14.9	114.6	368.6	4.4	1.6	-0.4	4.5	17.0	19.2	-0.3	16.5	11.5	16.9	6.6	-0.9	14.3	6.8	-1.5	-0.2	16.2
Blood Platelet Count	0.3	3.6	11.6	2.7	0.8	2.9	2.7	-0.7	0.6	0.9	1.6	1.2	0.0	1.0	3.4	1.3	2.2	2.9	2.1	0.5
Blood Red Count	1.5	14.7	30.6	-3.2	-1.7	-2.8	-3.7	-3.9	-4.9	-0.8	-5.5	-3.6	-5.1	-5.0	-2.6	-5.3	-4.0	-0.4	-0.1	-5.5
Blood White Count	10.5	78.1	249.6	2.9	1.5	0.2	3.2	14.3	15.8	-0.1	13.3	9.3	14.0	6.1	0.6	11.8	5.3	-2.0	0.9	13.5
Heel T-Score	0.3	2.7	8.1	-0.3	2.8	0.9	2.7	-1.1	-1.4	-0.7	-2.2	-1.4	-0.1	-2.3	1.6	-0.8	-2.1	-1.9	-1.4	-0.9
BMI	0.1	0.4	1.1	-0.8	-0.2	0.1	0.2	1.0	1.0	0.6	1.0	0.6	0.7	-0.3	-0.5	-0.1	0.7	0.9	0.3	0.1
Height	0.1	1.5	7.2	0.1	0.4	-0.5	-1.0	-1.1	-1.8	-0.5	-1.4	-2.7	-1.1	-2.3	0.1	-1.1	-0.3	-1.3	-0.3	-0.9
Waist Hip Ratio (WHR)	0.2	1.0	3.0	-1.0	-0.6	-1.6	0.7	0.3	0.6	-0.8	0.3	1.2	1.4	-1.3	-1.2	0.4	-0.2	-1.7	-0.5	1.1
Systolic Blood Pressure	0.1	0.6	2.2	1.3	-0.7	0.1	-0.1	-1.5	-1.2	-0.2	-1.1	0.2	-0.4	-0.6	0.4	-0.8	-0.7	-0.1	0.7	-0.9
Smoking Status	0.8	2.0	8.2	-2.0	0.4	-0.3	2.5	1.2	1.6	-0.0	0.6	0.4	2.9	-0.7	0.3	0.8	-1.3	-2.3	-0.3	1.5
Allergy or Eczema	0.4	1.0	8.9	0.2	1.7	0.6	0.3	0.7	0.0	3.0	0.2	-1.2	-0.1	0.6	1.4	-0.2	0.1	0.6	0.8	-0.0
Cardiovascular Disease	0.7	2.3	9.4	1.1	0.1	0.1	0.7	-3.1	-2.6	-1.1	-1.8	-0.2	-1.8	-2.1	1.6	-1.3	0.6	0.7	0.1	-2.1
Hypothyroidism (self reported)	0.8	1.9	5.6	0.1	-0.9	1.3	-0.2	1.8	1.9	-0.5	2.4	1.5	1.7	0.6	-0.5	1.2	2.0	-0.4	-1.1	2.0
Respiratory disease	0.3	0.7	4.2	0.2	2.0	1.4	0.9	-0.3	-0.2	1.1	-0.7	0.0	0.5	0.5	0.8	-0.3	-1.3	-0.7	-0.4	0.2
Type 2 Diabetes (T2D) (2018)	1.2	2.2	13.0	1.0	-0.5	-0.9	-1.8	-0.7	-2.2	0.7	-1.4	-3.6	-2.1	-0.5	0.2	-1.5	0.0	1.0	1.0	-1.4
Lung FEV1/FVC ratio	0.2	1.2	4.5	1.1	2.1	1.8	1.0	0.3	0.7	-0.9	-0.1	-0.3	0.6	-0.9	2.0	-0.5	-0.6	-1.5	-1.0	-0.3
Lung FVC	0.4	1.9	9.2	1.1	2.2	-0.2	3.0	0.7	0.8	1.7	0.7	-1.9	1.6	0.6	1.6	1.1	0.5	-0.2	0.4	1.1
Neuroticism	0.5	1.1	3.0	-1.5	0.3	0.3	1.5	-1.7	-1.5	-1.2	-1.2	0.6	0.0	-1.3	0.3	-0.5	0.2	-1.3	-1.0	0.7
Chronotype (morning person)	1.7	3.8	18.8	1.8	0.8	-1.4	-0.3	-0.8	-2.1	2.4	-2.8	-4.3	-1.5	-0.2	1.5	-2.7	-2.7	-0.5	0.8	-1.5
Hair Pigment	0.0	1.0	3.1	-1.0	-0.9	1.8	-0.5	1.5	0.7	1.3	0.4	0.4	0.5	1.8	-1.3	0.8	-0.3	-1.2	-0.0	0.5
Tanning	0.2	2.3	7.0	-0.3	-0.5	-0.9	-1.0	-2.1	-2.6	-0.1	-2.0	-1.6	-2.5	-1.5	1.2	-1.4	-0.3	1.2	0.9	-2.2
Hand grip strength (left)	0.5	1.2	5.0	1.6	0.6	0.0	0.7	1.7	2.2	-0.4	1.2	0.7	2.0	0.7	0.4	0.9	-0.1	-0.7	-0.8	1.1
Number of treatments/medications taken	0.8	1.5	4.4	-0.6	0.5	0.5	0.9	-2.1	-1.9	-1.3	-1.0	-0.4	0.6	-2.0	0.8	1.2	0.6	-2.1	-0.5	1.3
Average weekly spirits intake	2.0	2.5	13.5	-3.7	-1.6	-1.1	-0.2	0.7	1.6	-2.3	1.2	1.6	1.2	-0.8	-1.8	0.6	-0.0	-0.4	2.4	1.2
Sensitivity / hurt feelings	0.3	0.6	2.4	-1.5	0.1	0.3	1.0	-0.3	-0.5	0.0	-1.0	0.1	0.6	-0.0	0.4	0.0	-0.7	-1.6	-0.9	0.9
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.5	-0.2	-0.2	0.8	-0.2	-0.3	-0.5	0.4	0.1	0.2	-0.0	1.0	-0.5	0.7	0.8	-0.5	-1.2	0.8
Hearing difficulty/problems: Yes	2.3	3.4	12.5	-1.1	1.5	0.5	-0.3	-1.6	-2.1	0.3	-3.2	-1.8	-0.7	-2.4	0.7	-1.5	-2.9	-3.5	-1.7	-1.3
Relative age of first facial hair	0.5	1.1	2.9	1.4	1.1	1.5	0.9	0.5	0.7	0.2	1.0	0.7	1.0	1.0	-0.2	1.7	0.9	-0.7	-1.4	1.4
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	2.7	0.2	1.1	0.5	1.0	-0.3	-0.8	-0.6	-1.2	-0.7	0.0	-1.6	1.2	-0.1	-0.3	-0.9	-0.2	0.2
Ever used hormone-replacement therapy (HRT)	0.9	1.2	6.2	0.0	0.3	-0.9	0.6	0.5	-0.5	1.3	-0.9	-2.5	0.6	0.4	-1.0	-0.9	-0.9	-1.7	-1.9	-0.3
Ever had hysterectomy (womb removed)	0.7	0.8	3.6	-0.6	0.1	0.0	0.5	0.1	-0.3	-0.5	-1.3	-1.4	0.1	-0.6	-0.5	-1.4	-1.9	-0.4	-1.1	-1.1
Systolic blood pressure, automated reading	0.2	0.5	2.5	0.6	0.2	1.6	0.2	-1.4	-1.1	-0.4	-0.9	-0.3	-0.0	-0.2	0.1	-0.7	-0.4	-0.5	-0.6	0.0
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	2.9	1.7	1.4	-0.3	1.0	-0.1	0.1	0.2	1.2	0.4	0.4	0.6	1.6	0.7	1.6	1.7	1.1	0.6
Angina	1.0	1.3	7.2	0.1	2.7	-0.4	1.5	-0.7	-0.8	1.0	-1.5	-1.0	-0.1	-0.8	1.7	-1.3	-1.3	-0.4	-0.1	-0.5
Medication for hormone replacement therapy	1.4	1.5	5.3	-0.5	0.2	-0.7	0.4	-1.1	-1.2	-0.5	-1.6	-1.6	-0.5	-2.3	-0.9	-1.5	-1.3	-1.5	-1.0	-1.8
Vitamin and mineral supplements	0.7	1.0	4.8	0.1	1.1	0.8	0.6	2.0	1.6	2.2	1.0	0.4	1.0	0.5	0.5	-0.1	0.0	0.3	0.2	-0.5
Supplements: Zinc	0.5	0.5	2.7	1.1	-0.2	-0.2	-1.3	0.0	-0.2	-0.3	-0.1	-0.1	0.8	0.4	-0.7	-0.0	-0.2	-1.6	-1.1	1.0
Medication: Co-codamol	0.6	0.7	2.4	-1.1	1.0	0.1	1.1	-1.0	-0.2	-1.6	-0.5	0.1	0.6	-0.6	0.2	-1.1	-0.9	-1.1	0.0	0.2
Medication: Metformin	2.2	3.1	10.4	-0.1	1.1	-0.4	-0.4	-2.4	-3.2	-0.0	-2.3	-3.2	-2.3	-1.6	0.6	-2.4	-0.3	0.8	1.0	-2.0
Diabetes (father)	0.7	0.9	5.4	-0.1	-1.9	0.9	-2.3	0.6	-0.2	0.1	0.7	0.1	-0.5	-0.6	-1.0	0.3	1.4	-0.0	-0.7	-0.7
Diabetes (mother)	1.3	1.7	4.5	0.3	0.3	0.8	0.1	-1.7	-2.1	1.0	-1.4	-1.7	-1.5	-1.8	0.4	-1.8	-0.2	1.3	-0.3	-1.9
Severe depression (siblings)	0.8	0.9	2.6	-1.0	0.8	0.3	1.6	-0.9	-0.3	0.2	-1.2	0.3	0.5	-0.8	0.6	-1.2	-1.5	-1.6	-0.2	-0.2
Pack years adult smoking proportion	0.5	0.7	4.2	-0.5	-0.3	0.4	0.9	1.0	0.3	2.1	0.5	0.7	0.1	0.7	-0.9	0.8	0.8	1.2	-0.7	-0.1
Impedance of leg (right)	0.1	0.7	2.6	-0.3	-0.5	-0.9	-1.4	-0.4	-0.7	-0.4	-0.9	0.0	-0.8	-0.5	-1.6	-0.9	-1.2	-0.8	0.6	-0.4
Leg fat-free mass (left)	0.1	0.5	3.5	0.5	0.9	0.1	1.0	0.2	0.3	0.3	0.1	-1.0	0.5	-0.9	1.9	-0.2	-0.2	-0.0	-0.3	-0.2
Trunk fat percentage	0.4	1.5	6.1	-1.6	1.4	-1.6	1.3	-0.4	0.1	-0.3	-0.9	0.2	1.1	-2.5	1.7	-0.6	-1.6	-1.5	0.2	0.2
Hand grip strength (right)	0.4	1.1	4.0	1.3	0.6	-0.2	0.3	1.5	2.0	0.2	1.1	0.3	2.0	0.1	0.3	1.2	-0.3	-1.1	0.1	1.3
Townsend deprivation index at recruitment	0.7	1.0	6.3	0.4	0.8	0.9	2.5	0.4	0.5	-0.6	0.1	-0.5	1.8	-0.4	0.2	0.5	-0.6	-1.2	-1.3	0.6
Current tobacco smoking	0.3	0.6	3.1	-0.9	0.0	-1.0	1.8	0.7	0.9	0.6	0.5	0.2	0.5	-1.2	-0.2	-0.4	-0.4	0.8	0.2	-0.4
Average weekly fortified wine intake	1.4	1.6	7.9	0.4	2.8	-0.0	2.1	-0.8	-0.5	-0.4	-1.4	-0.5	0.4	-0.6	0.8	-0.8	-1.8	-2.0	-1.7	-0.0
Maternal smoking around birth	1.1	1.6	5.6	-0.6	1.6	-2.4	2.2	-0.5	-0.9	0.1	-1.7	-0.7	0.1	-1.9	1.0	-0.4	-2.1	-1.0	-0.2	-0.3
Fed-up feelings	0.5	0.8	2.8	-1.4	-0.8	-0.9	0.4	-0.8	-1.1	-0.1	-0.9	-0.7	-0.9	-1.5	-0.3	-1.7	-0.4	0.5	0.2	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	3.6	-1.5	-0.8	-0.3	0.2	0.2	-0.2	0.6	0.0	0.1	-0.5	0.4	-1.9	-0.5	-0.1	0.1	-0.1	-0.8
Relative age voice broke	0.6	0.9	4.7	0.3	0.4	-0.1	0.0	0.5	1.0	-1.2	1.1	1.3	1.2	0.3	-2.2	0.9	0.3	-0.6	-1.0	1.1
Taking other prescription medications	1.1	1.7	8.1	-0.4	1.5	1.0	0.7	-1.3	-1.7	-0.1	-2.2	-1.7	0.3	-0.4	0.7	-0.6	-1.9	-2.8	-0.6	0.5
Age when periods started (menarche)	0.3	0.7	2.5	0.3	-0.3	0.7	0.2	-0.3	0.4	-1.5	1.3	1.6	-0.4	-0.3	0.4	0.6	1.4	1.0	0.2	-0.6
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.6	-0.9	-0.2	-0.5	1.3	0.4	0.3	0.1	0.0	-0.6	0.4	-0.7	0.4	-0.0	-0.5	-0.1	0.5	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	2.9	1.5	0.6	-0.2	0.8	-0.7	-1.1	1.4	-1.2	-1.1	-1.2	-1.4	0.7	-0.6	-1.2	1.6	0.9	-1.7
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	7.4	1.4	0.8	1.5	0.4	-0.1	0.4	-0.1	0.4	1.2	0.7	0.1	0.1	-0.1	0.3	-1.0	-2.7	-0.0
Qualifications: CSEs or equivalent	0.4	0.5	3.3	-0.9	-0.9	-1.1	-0.9	-0.3	0.2	-0.1	-0.2	1.8	0.3	-0.6	0.1	-0.0	-0.8	-0.5	-0.3	0.2
Serious illness, injury or assault to yourself	1.3	1.5	6.2	0.8	-0.2	2.5	0.1	1.0	0.7	-0.4	1.8	0.7	0.3	1.3	-0.5	1.2	2.2	1.6	1.2	1.2
High blood pressure	0.5	1.5	6.7	1.5	-0.6	0.6	0.5	-2.6	-2.4	-0.6	-0.8	0.0	-1.5	-1.4	0.7	-0.2	1.5	0.6	-0.9	-1.1
Hayfever, allergic rhinitis or eczema	0.4	1.0	3.3	-0.0	0.9	1.0	-0.1	-0.7	-1.1	1.6	-0.9	-1.8	-0.9	-0.6	1.5	-0.9	-0.4	-0.0	0.5	-1.0
Multivitamins +/- minerals	0.4	0.5	2.7	0.2	0.1	0.5	-0.2	-1.6	-1.1	-1.2	-0.8	0.1	-0.8	-0.9	0.6	-0.2	-0.2	0.3	-0.3	0.1
Stomach or abdominal pain in last month	1.0	1.2	3.4	-1.8	1.5	0.5	0.6	-0.0	0.8	-1.4	-0.4	1.8	1.3	-1.1	1.3	-0.6	-1.2	-1.2	0.6	0.5
Supplements: Glucosamine	0.3	0.4	1.6	0.4	-0.4	0.8	0.7	0.2	0.2	-0.9	0.2	-0.3	0.9	0.4	0.4	0.5	0.1	-1.2	-0.0	1.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.9	-0.2	0.2	-0.4	0.9	0.0	0.3	-0.4	-0.0	1.0	0.4	-0.4	0.9	0.3	-0.2	0.1	0.5	0.0
Medication: Atenolol	0.5	0.6	3.8	0.8	0.8	-0.1	0.3	-0.3	-0.7	2.0	-0.7	-0.1	-0.5	-0.4	1.2	-0.1	0.1	0.2	-1.0	-0.7
Medication: Levothyroxine sodium	1.1	1.9	5.2	0.3	-1.7	1.0	-0.8	1.5	1.7	-1.0	2.3	1.5	1.4	1.1	-0.7	1.4	2.2	-0.4	-0.6	2.0
Sitting height	0.2	1.1	7.9	0.0	-0.7	-0.7	-0.8	0.0	-0.9	1.4	-0.9	-2.8	-1.1	0.2	-0.5	-1.5	-1.0	-0.2	-0.0	-1.1
Chronic bronchitis/emphysema (father)	0.8	0.9	3.3	0.1	-0.1	-1.1	1.8	-0.0	0.6	-1.3	0.6	1.0	1.1	-0.5	0.6	1.5	0.5	-0.5	0.4	1.8
High blood pressure (mother)	2.8	4.0	9.9	-0.7	-0.5	1.2	1.2	2.4	3.1	-1.1	2.7	2.6	3.0	1.6	-0.1	2.3	1.2	-1.8	-0.9	3.1
Body mass index (BMI)	0.2	0.7	3.3	-1.0	1.1	-0.4	1.8	0.0	0.3	0.0	-0.0	0.5	1.2	-1.6	1.1	0.5	-0.2	-0.5	-0.5	0.5
Impedance of leg (left)	0.2	0.9	4.8	-0.9	-1.3	-1.2	-1.7	0.1	-0.2	-0.6	-0.5	0.3	-0.4	-0.2	-2.2	-0.5	-1.0	-0.9	0.9	-0.0
Leg predicted mass (left)	0.1	0.4	3.4	0.4	0.8	0.1	1.0	0.2	0.4	0.1	0.2	-0.9	0.6	-0.9	1.8	-0.1	-0.1	0.1	-0.2	-0.2
Trunk fat mass	0.3	1.4	6.6	-1.3	1.5	-1.3	1.5	-0.4	-0.0	-0.2	-0.9	-0.1	0.8	-2.6	1.8	-0.6	-1.4	-1.2	0.2	-0.0
Waist circumference	0.3	1.2	5.8	-0.8	1.4	-1.6	1.7	-0.1	0.1	0.0	-0.6	-0.1	1.2	-2.4	1.4	0.2	-0.8	-1.5	-0.8	0.5
Number of incorrect matches in round	0.4	0.6	1.7	0.4	1.1	1.3	-0.2	0.8	1.0	0.1	-0.1	1.0	1.0	0.8	-0.2	-0.1	-1.0	-0.8	-0.7	1.2
Past tobacco smoking	0.6	1.1	5.2	2.3	-0.1	0.4	-0.9	0.1	-0.1	-0.3	0.3	0.2	-1.8	0.2	-0.5	-0.2	1.1	2.3	-0.2	-1.7
Alcohol usually taken with meals	0.2	0.3	1.3	0.1	-0.4	-0.3	-1.1	-0.3	-0.0	-1.0	-0.0	0.0	-0.7	-0.3	-0.7	0.2	0.2	0.7	0.2	0.5
Nervous feelings	0.4	0.7	4.4	-0.8	0.2	0.5	-0.4	-0.7	-1.3	1.0	-0.8	-0.1	-0.2	0.6	-0.4	0.2	0.1	-1.3	-2.1	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	5.4	-1.6	0.4	-0.4	0.8	-0.3	-0.6	0.3	-1.1	-0.8	0.7	0.1	-1.1	-0.8	-1.2	-2.3	-1.3	0.2
Hearing difficulty/problems with background noise	2.1	3.4	14.0	-0.0	2.5	0.6	1.8	-0.4	-1.4	1.5	-2.6	-2.5	0.8	-0.3	0.6	-1.2	-2.4	-3.7	-2.9	-0.2
Hair/balding pattern: Pattern 2	0.7	0.9	4.0	-0.9	-1.4	-2.0	-1.3	0.7	0.2	0.6	-0.2	0.6	-0.3	1.2	-2.0	-0.1	-0.8	-0.2	0.1	-0.2
Had menopause	1.3	1.6	11.2	1.8	-0.2	3.3	-1.4	0.6	-0.2	1.0	0.4	-0.9	-0.8	0.9	-1.7	0.3	1.0	0.9	-1.4	-0.1
Had other major operations	0.8	1.0	3.0	-0.9	-0.3	-1.5	1.7	0.2	0.2	-0.7	1.1	-0.2	0.6	-0.6	0.4	1.4	1.6	0.2	1.2	1.1
Forced vital capacity (FVC)	0.3	1.1	5.8	1.7	1.2	0.2	1.0	0.8	0.9	1.3	0.5	-2.4	0.7	-0.4	1.6	-0.1	-0.2	0.2	0.8	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	4.3	1.0	0.2	-1.1	0.8	-1.4	-1.9	1.2	-2.1	-1.7	-1.6	-1.4	0.3	-1.5	-1.9	1.2	0.8	-2.0
Ever unenthusiastic/disinterested for a whole week	1.4	1.8	5.6	-1.8	1.0	1.1	1.7	-1.7	-1.6	-0.4	-2.4	-0.4	-0.8	-0.8	0.7	-1.7	-1.6	-1.2	0.1	-1.2
Qualifications: None of the above	0.9	2.0	7.0	-1.4	-0.0	-1.8	1.2	1.0	0.3	0.8	0.3	-0.1	2.1	0.5	-0.3	2.0	0.5	-2.2	-2.2	2.6
Financial difficulties in last 2 years	2.0	2.7	7.7	-1.0	-1.5	-1.1	-1.9	2.8	2.8	-0.4	2.4	2.1	1.6	1.5	-0.5	1.6	0.8	0.5	-0.2	2.0
Mouth/teeth dental problems	0.8	1.3	4.1	2.0	-0.4	-1.2	-1.6	-1.1	-1.1	-0.4	-0.1	-0.7	-1.4	-0.1	-1.6	-0.4	1.1	1.1	-1.5	-1.0
Heart attack	0.8	1.0	4.9	0.8	1.7	-0.8	0.6	1.2	0.3	2.2	-0.1	-0.7	0.7	0.0	1.5	0.8	0.1	-0.6	-0.9	0.8
Allergy	0.9	2.1	6.5	-0.1	-1.9	-2.1	-0.5	1.5	1.6	-1.4	1.7	1.8	0.9	0.8	-2.5	1.5	1.2	0.4	-0.3	1.3
Pain all over the body in last month	1.0	1.0	4.7	-1.7	-0.8	-0.2	-1.0	-0.9	-1.1	0.3	-0.8	-0.6	-2.2	-0.5	-1.1	-0.8	-0.3	0.9	0.8	-1.2
Diabetes (self-reported)	1.1	1.6	6.4	0.4	0.5	0.7	-0.5	-1.6	-2.4	0.2	-1.8	-2.5	-1.4	-0.8	1.4	-0.9	-0.3	0.5	1.3	-1.1
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	4.0	-0.0	0.8	-0.6	0.1	-0.7	-1.1	2.0	-0.9	-1.9	-0.7	-0.4	1.4	-0.3	-0.1	-1.0	-0.1	-0.9
Medication: Ramipril	0.8	1.0	7.0	1.5	-0.3	-0.6	0.1	-0.5	-0.9	0.3	0.9	-0.1	-0.6	-0.7	-0.9	1.2	2.6	1.6	-0.7	0.0
Medication: Simvastatin	2.4	3.5	11.1	0.5	-0.1	-0.7	-1.0	-3.0	-3.3	-0.5	-2.1	-1.9	-3.1	-2.4	0.9	-1.9	0.5	1.5	1.2	-2.3
Fluid intelligence score	0.7	1.4	7.4	2.1	0.4	0.8	-0.2	-1.3	-0.6	-1.0	-0.3	-0.3	-1.4	-0.6	2.7	0.5	0.7	1.6	1.6	-0.5
Illnesses of siblings	1.9	2.6	7.1	0.2	-0.6	-1.0	-1.6	2.3	2.2	0.7	2.5	1.6	0.5	1.9	-0.3	2.7	1.9	1.6	0.7	1.8
Neuroticism score	0.5	1.1	3.4	-1.8	-0.7	0.8	0.7	-1.8	-1.8	-0.1	-1.4	-0.0	-0.6	-0.2	-0.2	-0.6	-0.1	-1.3	-1.3	-0.1
Weight	0.1	0.6	3.2	-0.4	1.1	-0.8	1.3	0.3	0.3	0.1	-0.2	-0.7	0.9	-1.8	1.3	0.1	-0.6	-0.6	0.0	0.2
Impedance of arm (right)	0.2	1.0	2.3	0.4	0.5	-1.5	-1.1	-1.0	-0.7	-0.4	-1.3	0.1	-0.7	-1.1	1.5	-1.3	-1.4	-0.7	1.2	-0.4
Arm fat percentage (right)	0.4	1.7	8.3	-1.1	1.9	-1.1	1.7	-1.1	-0.6	-0.2	-1.3	0.2	0.8	-2.9	2.2	-0.4	-1.2	-1.0	-0.1	-0.1
Trunk fat-free mass	0.0	0.3	1.0	0.5	0.4	0.7	0.4	0.8	0.3	0.5	0.6	-1.0	0.2	-0.0	0.2	0.6	0.6	0.5	-0.6	0.2
Hip circumference	0.2	1.0	4.7	-0.6	1.4	-1.1	1.4	0.2	0.6	-0.1	-0.1	0.3	1.1	-2.2	2.0	0.2	-0.7	-0.6	0.0	0.5
Time employed in main current job	0.6	0.7	1.7	-1.3	-0.9	0.3	-1.1	-0.7	-0.8	-0.8	-1.2	-0.1	-0.4	-0.7	-0.6	-1.1	-0.4	-1.2	-1.1	-0.3
Alcohol intake versus 10 years previously	0.5	0.7	3.1	-0.5	-0.0	0.5	1.3	-0.6	-1.0	-0.8	-1.1	-0.6	-0.8	-0.2	0.9	-0.9	-0.8	-0.1	-0.1	-1.8
Father’s age at death	1.1	1.5	7.2	0.5	-0.6	0.4	-0.3	-2.1	-0.9	-2.7	-0.3	1.8	-1.5	-1.0	1.3	0.2	0.5	1.5	0.9	-1.1
Worrier / anxious feelings	0.3	0.6	3.8	-1.4	-0.5	0.1	0.6	-0.4	-0.2	0.2	-0.9	0.5	0.5	0.4	0.5	-0.0	-1.1	-2.0	-0.2	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	10.3	-3.2	-0.0	-0.3	-0.2	0.7	0.3	0.6	-0.6	0.7	0.9	0.4	-0.5	0.6	-1.5	-1.2	-0.1	1.4
Falls in the last year	0.8	1.1	3.7	-1.6	1.9	0.8	1.5	-1.4	-0.5	-0.5	-1.2	1.7	0.4	-0.7	0.5	0.2	-1.2	-0.7	-0.3	0.5
Hair/balding pattern: Pattern 3	1.3	1.9	5.1	-0.7	-0.7	0.9	-1.1	1.9	1.2	0.1	1.1	-0.4	1.7	2.0	-1.8	1.9	0.3	-1.8	-0.4	2.3
Number of live births	0.7	1.0	3.8	-0.5	0.7	1.7	0.7	-0.8	-1.0	0.5	0.3	0.4	-0.0	0.1	-0.3	1.5	1.6	0.4	-2.0	1.1
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	5.4	1.3	1.3	0.0	1.3	0.3	0.5	0.4	-0.0	-2.0	0.4	-1.3	2.3	-0.3	-0.6	-0.1	1.0	-0.2
Pulse rate	0.5	0.8	4.7	-0.6	-0.4	0.6	0.4	-0.8	-0.4	-1.5	-0.3	-0.2	-0.0	-2.2	0.3	-0.9	0.4	-0.9	1.5	-0.7
Happiness	0.6	0.7	2.6	-1.0	0.3	1.3	0.8	0.2	0.3	-1.5	-0.2	0.4	0.6	-0.3	1.6	-0.4	-0.2	-1.6	-0.1	0.6
Noisy workplace	0.3	0.3	0.9	-0.6	0.2	-0.9	0.3	-0.4	-0.4	-1.0	-0.3	0.6	0.2	-0.5	-0.7	-0.0	0.6	-0.9	-0.9	0.3
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.6	0.4	0.7	1.4	1.9	0.4	0.9	-0.4	1.6	-0.1	0.7	0.5	0.7	1.1	1.6	0.4	0.7	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	2.9	-0.8	0.5	-0.2	-0.7	-0.1	-0.6	0.8	-0.3	-0.9	-0.9	0.9	-1.7	-0.5	0.3	0.8	-0.7	-0.2
Mouth/teeth dental problems: Dentures	0.7	1.2	3.2	-1.3	0.4	0.8	1.6	1.1	1.1	-1.0	-0.1	0.0	1.8	-0.1	0.7	0.6	-1.2	-1.8	1.2	1.2
Asthma	0.3	0.5	1.7	0.3	0.6	1.0	0.0	-1.3	-1.3	0.3	-1.0	-0.7	-0.6	0.6	0.7	-0.9	-0.7	-0.1	0.3	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.8	-0.8	-0.1	1.3	0.4	0.1	0.0	-0.0	0.3	-0.7	0.8	-0.4	-0.7	0.6	0.5	-0.7	-1.3	0.4
Medication: Cholesterol lowering	1.2	1.8	5.0	0.8	1.2	0.6	-0.3	-2.1	-2.0	0.7	-1.3	-0.8	-2.1	-0.9	2.2	-1.6	0.1	1.2	1.0	-1.5
Depression (self-reported)	0.7	0.8	5.4	-0.1	-0.1	-0.4	0.4	0.3	0.5	-0.6	-0.0	0.6	1.1	-0.3	-1.1	0.1	-0.3	-2.2	-2.3	0.6
Medication: Lansoprazole	0.2	0.3	0.9	-0.4	0.8	0.6	0.3	-0.5	-0.2	-0.9	-0.5	0.1	-0.2	0.9	-0.1	-0.6	-0.5	-0.1	0.0	-0.1
Prospective memory result	0.4	0.5	2.3	0.4	-1.2	0.0	-1.5	-0.6	-1.0	-0.0	0.1	-0.4	-0.9	0.1	0.5	0.3	1.2	0.1	1.2	0.0
Lung cancer (father)	0.5	0.6	2.6	-0.8	0.6	-0.7	0.3	-0.3	-0.3	-0.6	-0.5	0.7	0.2	-1.6	1.1	0.9	-0.0	0.1	1.4	0.4
Illnesses of mother	0.7	0.8	3.7	1.2	-1.9	-0.3	-1.9	-0.2	-0.1	-0.3	0.5	0.0	-1.0	0.5	-0.8	0.3	1.1	1.1	0.4	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	6.6	1.3	1.9	1.6	1.8	0.1	0.6	0.3	-0.1	-1.3	0.6	-1.1	2.6	0.0	-0.7	0.0	1.2	-0.2
Pulse wave Arterial Stiffness index	0.4	0.4	1.8	1.2	-0.6	0.2	-0.5	0.2	-0.0	0.7	1.0	0.3	-0.1	-0.6	-0.8	0.5	1.3	0.9	0.1	0.1
Impedance of arm (left)	0.2	0.7	3.4	0.3	0.4	-1.8	-1.4	-0.5	-0.0	-0.1	-0.7	0.5	-0.5	-0.7	0.9	-1.1	-1.2	-0.6	1.1	-0.2
Arm fat mass (right)	0.2	1.0	5.6	-1.0	1.2	-0.9	1.6	-0.4	-0.0	-0.1	-0.6	0.2	0.9	-2.4	1.7	-0.0	-0.8	-0.7	-0.1	0.1
Trunk predicted mass	0.1	0.3	0.9	0.5	0.4	0.8	0.4	0.8	0.3	0.5	0.7	-1.0	0.2	-0.0	0.2	0.6	0.7	0.5	-0.6	0.2
Standing height	0.1	0.6	5.0	0.9	-0.2	-0.5	-1.1	0.7	0.1	0.2	-0.0	-2.2	-0.4	-0.5	0.2	-0.8	-0.6	-0.2	0.6	-0.3
Length of working week for main job	0.2	0.3	1.9	0.3	-0.1	-1.4	0.5	0.1	-0.1	0.2	0.0	-0.5	-0.4	0.3	0.1	-0.4	-0.2	0.9	0.5	-0.4
Exposure to tobacco smoke at home	1.5	1.7	5.2	-2.3	-1.3	0.8	-0.6	-1.9	-1.5	-1.8	-1.4	0.3	-1.7	-1.2	0.2	-1.3	-0.8	0.9	1.0	-1.2
Breastfed as a baby	0.5	0.6	3.4	0.4	0.5	-0.9	-0.9	0.1	-0.0	-0.4	0.3	-1.1	0.3	0.3	-0.4	1.8	0.8	-0.5	-0.0	1.2
Tense / ‘highly strung’	2.2	3.6	11.6	-1.3	0.4	-0.9	1.1	-2.2	-2.6	0.4	-3.4	-1.6	-1.4	-1.2	0.2	-2.6	-2.6	-2.4	-1.9	-1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	2.2	3.3	10.1	-1.2	1.6	1.0	2.1	-1.9	-1.7	0.1	-2.7	-0.6	-0.1	-1.7	0.9	-2.4	-2.9	-3.2	-1.8	-1.4
Hair/balding pattern: Pattern 4	0.7	1.6	4.1	-0.2	-0.1	-2.0	2.0	-1.2	-0.7	-0.5	-0.6	-0.2	-0.5	-1.7	1.5	-1.7	-0.7	1.4	2.0	-1.2
Birth weight of first child	1.1	2.0	7.0	-0.2	0.4	0.6	1.8	1.1	1.4	0.1	1.7	2.1	1.5	0.9	-0.0	2.6	2.0	0.2	-1.0	2.1
Peak expiratory flow (PEF)	0.6	1.3	4.9	0.7	2.1	1.3	2.2	0.1	0.6	0.4	-0.4	-0.7	1.0	-1.4	2.0	0.8	-1.0	-0.9	-0.6	0.7
Pulse wave reflection index	0.3	0.4	2.0	0.8	-0.2	-0.5	-0.2	-0.4	-0.6	1.4	0.0	0.2	-0.5	0.4	-0.9	0.2	-0.1	1.2	-1.0	-0.3
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.8	-0.9	-0.9	0.1	-0.4	-1.1	-1.0	-1.7	-1.1	0.5	-0.7	0.2	0.7	-0.6	-0.5	-1.0	-0.4	-0.1
Loud music exposure frequency	2.2	2.4	8.3	-1.9	-2.7	-1.1	1.0	-1.8	-0.8	-2.9	0.4	0.2	-1.1	-2.6	-0.9	-0.3	0.9	2.0	0.4	-1.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.3	0.4	0.3	1.8	0.9	0.0	0.0	0.4	0.8	0.1	0.1	0.7	-1.1	1.0	1.1	0.6	-0.3	-0.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	2.2	-1.5	0.2	-0.9	0.3	0.1	0.1	0.7	0.2	1.1	-0.2	0.4	0.4	0.3	-0.1	0.9	0.9	0.3
Blood clot in the leg (DVT)	3.6	4.6	11.2	0.6	2.6	1.3	0.6	-3.1	-2.7	-0.2	-3.2	-1.8	-2.5	-3.3	2.8	-2.1	-1.8	0.2	-0.2	-2.3
Medication: Paracetamol	2.0	3.3	11.8	-2.6	0.9	0.6	2.6	0.9	1.0	0.3	0.0	0.9	3.1	-0.1	0.5	1.5	-0.9	-3.4	-2.8	2.4
Headache pain in last month	0.8	1.4	4.8	-1.7	0.2	0.7	0.4	-0.1	0.6	-1.4	0.1	2.2	1.2	-1.1	0.1	1.4	0.2	-1.4	-1.6	2.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	4.9	-0.2	-0.9	0.0	0.4	2.1	2.2	-0.3	1.4	0.9	1.6	0.9	-1.5	1.4	-0.2	-0.4	-0.4	1.2
Glaucoma (self-reported)	1.2	1.4	5.3	-1.3	0.8	-1.0	-0.0	-0.9	-1.6	0.0	-1.9	-2.3	-0.9	-0.1	0.9	-0.4	-1.5	-0.7	1.9	-0.4
Gout (self-reported)	0.4	0.6	3.1	0.5	-0.8	1.8	-1.3	-0.3	-0.3	-0.3	-0.7	0.2	-1.0	0.5	0.5	-0.6	-0.9	0.2	0.3	-1.0
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	5.1	0.4	-1.4	0.6	-0.4	1.5	1.5	0.1	2.3	1.1	1.2	1.2	-0.6	1.0	2.2	-0.1	-1.1	1.9
Medication: Amlodipine	1.1	1.6	3.9	0.9	-2.0	-1.8	-1.2	-1.1	-1.6	0.9	-0.4	-1.7	-1.7	-0.1	-0.2	-0.9	1.1	1.1	-1.0	-1.7
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.8	-0.5	0.8	-0.1	-0.2	0.4	0.4	0.7	-0.2	0.4	0.4	-0.2	0.1	-1.1	-1.4	-0.3	0.1	-0.4
Birth weight	0.4	0.8	3.8	-1.1	-0.8	-0.4	-0.2	-0.5	0.5	-1.9	1.2	1.5	-0.1	1.0	-0.3	0.7	0.8	0.9	0.8	0.0
Chronic bronchitis/emphysema (mother)	2.0	2.3	8.7	-0.6	2.5	-0.6	2.9	-1.0	-1.1	-0.3	-2.1	-1.3	-0.4	-1.3	1.7	-1.1	-2.4	-0.3	1.7	-1.1
High blood pressure (siblings)	0.8	1.2	3.7	0.6	1.0	0.7	1.3	-1.4	-1.5	0.5	-1.2	-1.5	-0.6	-0.2	1.3	-1.9	-0.5	-0.5	0.3	-1.5
Forced vital capacity (FVC), Best measure	0.3	0.9	2.4	1.2	1.4	1.5	1.2	0.5	0.8	0.9	0.4	-1.5	0.8	-0.1	1.5	0.4	-0.3	0.1	1.0	0.2
Body fat percentage	0.3	1.4	6.4	-1.5	1.3	-1.6	1.3	-0.6	-0.2	-0.5	-1.0	0.1	0.9	-2.5	1.4	-0.5	-1.4	-1.4	0.1	0.1
Leg fat percentage (right)	0.3	1.1	6.0	-1.5	1.1	-1.3	1.3	-1.0	-0.9	-0.3	-1.2	-0.2	0.4	-2.5	0.6	-0.5	-1.1	-1.1	-0.1	-0.0
Arm fat-free mass (right)	0.1	0.4	1.2	0.2	0.1	0.5	0.7	1.1	0.7	0.6	0.9	-1.0	0.5	0.1	-0.2	0.5	0.4	0.4	-0.7	0.1
Exposure to tobacco smoke outside home	0.9	1.2	4.1	-0.7	-0.3	-0.0	-0.3	-1.4	-2.0	-0.0	-1.9	-1.9	-0.9	-1.4	0.5	-0.5	-1.2	-0.9	-0.1	-0.8
Comparative body size at age 10	1.0	2.6	11.6	-1.1	-0.9	-0.6	-1.0	2.5	1.8	2.6	2.2	0.2	1.0	3.4	-0.7	2.1	1.1	0.6	-0.1	1.0
Number of full brothers	0.5	0.7	2.3	0.1	0.3	0.0	1.0	-0.8	-1.2	0.3	-1.3	0.3	-0.0	-0.7	0.7	0.4	-0.5	-1.5	-1.5	-0.3
Worry too long after embarrassment	1.1	1.9	8.8	-1.6	0.1	-0.7	-0.1	-1.3	-1.8	0.9	-1.7	-1.6	-0.2	0.1	-0.8	-1.5	-0.9	-2.2	-3.0	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	9.9	-1.1	0.2	-0.3	2.1	-0.1	-0.4	1.1	-0.8	-1.2	1.1	1.1	0.1	-1.1	-1.2	-3.1	-1.2	0.4
Wheeze or whistling in the chest in last year	0.6	1.0	2.7	-0.4	0.8	0.8	1.6	0.9	1.5	0.8	0.9	0.7	1.4	1.5	0.7	0.4	-0.9	-0.1	0.3	1.5
Number of children fathered	0.4	0.4	2.1	0.6	1.0	-0.1	0.6	-0.0	0.1	0.7	-0.3	0.4	0.2	0.4	1.4	0.2	-0.3	-0.7	-0.9	1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	3.6	1.3	1.9	-0.1	1.8	-0.3	0.7	-1.4	0.9	1.1	1.2	-1.8	1.5	1.1	1.2	0.2	-1.6	1.4
Age at first live birth	0.3	0.6	3.0	0.2	-0.2	0.0	-1.2	0.5	0.7	-0.2	1.4	0.4	-0.0	1.3	-0.3	0.3	1.7	0.5	0.2	0.6
Pulse wave peak to peak time	0.3	0.4	1.5	-1.0	0.8	-0.0	0.5	-0.1	0.1	-0.4	-0.8	-0.4	0.1	0.5	0.9	-0.4	-1.2	-0.7	-0.1	-0.1
Health satisfaction	0.7	0.8	4.4	-1.0	0.9	0.5	1.4	-0.2	-0.3	-0.3	-0.6	-0.7	0.7	-1.3	2.1	0.0	0.1	-1.6	-0.3	-0.1
Shortness of breath walking on level ground	0.6	0.7	2.0	-0.9	-0.3	-0.8	1.4	1.1	1.0	-0.4	0.9	0.3	1.0	0.2	1.0	1.2	1.0	-0.6	0.6	0.6
Qualifications: College or University degree	0.8	2.5	6.7	2.6	1.0	1.7	-0.3	-1.7	-2.0	0.2	-1.7	-2.6	-2.2	0.2	0.7	-2.0	-0.2	-0.1	-0.9	-2.2
Eye problems/disorders: None of the above	1.1	1.3	4.2	0.4	-0.9	0.9	1.4	1.7	2.1	-1.6	1.4	0.9	1.8	0.6	-0.1	0.9	-0.1	-0.3	0.6	0.7
Mouth/teeth dental problems: Loose teeth	0.6	0.8	2.8	-0.1	0.2	-1.7	1.2	-0.5	-0.3	-0.6	-0.8	-0.8	-0.1	-0.6	1.4	-1.2	-1.1	0.0	1.3	-0.5
Emphysema/chronic bronchitis	1.5	1.7	7.5	0.3	1.3	1.1	1.5	-1.9	-1.0	-0.8	-1.2	0.3	-0.3	-2.7	1.7	-0.9	-0.8	-1.5	-1.5	-0.5
Medication for pain relief, constipation, heartburn	0.9	1.6	6.5	1.4	-0.6	-0.4	-2.1	0.2	0.4	0.2	0.5	0.5	-1.9	1.7	-0.4	-0.8	-0.1	2.5	1.8	-1.4
Neck or shoulder pain in last month	1.4	2.1	7.7	-1.3	0.8	1.1	2.1	-1.1	-0.9	-0.7	-1.8	-0.0	1.3	-1.2	1.0	-0.3	-1.4	-2.8	-2.6	0.6
Medication: Blood pressure	0.3	0.6	3.1	0.7	0.5	-0.5	-0.1	-1.6	-1.8	0.5	-0.5	-0.1	-0.9	0.0	0.8	-0.2	1.2	0.2	-0.5	-0.3
Angina (self-reported)	1.4	1.8	6.2	0.0	2.5	-0.6	1.4	-1.3	-1.4	0.9	-2.1	-1.3	-0.7	-1.3	1.7	-1.6	-1.5	-0.2	-0.1	-1.0
Migraine (self-reported)	1.4	1.8	7.7	-1.0	-2.8	0.5	-2.0	-0.9	-1.2	-2.5	-0.2	0.4	-1.0	0.5	-2.1	0.3	0.9	-0.6	-1.3	0.0
Medication: Ibuprofen	0.5	0.6	1.9	-1.0	-0.1	1.0	0.1	-0.2	-0.1	-0.9	0.5	0.2	0.7	-1.1	-0.7	1.0	1.2	-0.6	-1.4	0.7
Medication: Allopurinol	0.2	0.3	1.1	1.0	-0.0	1.1	-0.2	-0.1	-0.1	-0.5	-0.6	0.3	-0.4	0.4	0.7	-0.2	-1.0	-0.4	-0.7	-0.5
Medication: Omeprazole	0.3	0.4	1.9	0.1	0.4	-0.1	0.3	-0.5	-0.4	-0.1	-0.9	0.5	0.2	-1.0	0.3	-0.5	-0.6	-1.4	0.9	-0.1
Medication: Seretide 50 evohaler	0.4	0.5	2.2	-0.6	0.7	-0.2	0.6	-0.7	-0.2	-0.1	-0.8	0.4	0.1	-0.6	0.8	-0.2	-1.5	-1.0	-0.7	0.8
Mean time to correctly identify matches	1.2	2.3	4.7	-0.8	-2.1	-0.6	-1.4	1.8	1.8	-1.1	2.2	1.8	1.0	1.8	-0.9	1.7	1.4	1.3	1.3	1.6
Heart disease (mother)	0.6	0.7	4.0	-2.0	0.8	-0.1	-0.0	-0.6	-0.3	0.2	-1.0	0.6	-0.7	-0.2	-0.5	-1.4	-1.6	0.2	-0.2	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.5	5.4	16.4	2.1	2.3	1.3	3.4	2.5	3.2	-0.7	2.2	1.7	4.0	-0.9	1.4	3.0	0.6	-2.0	-0.0	3.5
Whole body fat mass	0.3	1.2	6.0	-1.2	1.3	-1.2	1.5	-0.3	-0.0	-0.1	-0.8	-0.3	0.9	-2.5	1.6	-0.5	-1.3	-1.1	0.1	-0.0
Leg fat mass (right)	0.3	1.0	5.8	-1.2	1.1	-1.0	1.4	-0.5	-0.3	-0.3	-0.8	-0.3	0.6	-2.4	0.9	-0.7	-1.1	-0.8	0.0	-0.3
Arm predicted mass (right)	0.1	0.4	1.5	0.1	0.4	0.5	0.6	1.2	0.8	0.9	0.8	-1.1	0.7	0.3	-0.4	0.4	0.2	0.1	-1.0	0.1
Pulse rate, automated reading	0.6	1.8	10.1	0.3	-1.1	1.5	0.5	1.1	1.1	-0.7	2.4	0.7	1.0	-0.1	-0.4	2.0	3.2	0.4	1.3	0.8
Alcohol intake frequency.	1.5	3.6	11.6	0.4	-0.9	-1.3	-1.6	-2.1	-3.0	-0.4	-2.2	-2.5	-3.4	-1.4	0.7	-1.9	-0.4	1.2	1.1	-3.3
Comparative height size at age 10	0.4	2.0	7.8	-1.4	1.7	-1.0	0.6	-0.5	-0.4	-0.6	-1.8	-2.2	0.8	-1.1	1.7	-1.1	-2.8	-2.0	0.7	0.4
Number of full sisters	1.0	1.3	4.8	1.0	-0.7	0.0	-0.5	1.0	1.1	-1.2	1.7	1.1	0.8	-0.6	-0.5	2.2	1.7	1.1	0.2	1.4
Suffer from ‘nerves’	0.7	1.2	6.1	-2.0	-0.4	2.5	-1.3	-0.6	-0.8	0.4	-1.0	-0.1	-0.3	1.0	-0.0	-0.2	-0.6	-1.4	-1.4	0.4
Overall health rating	0.9	1.8	7.8	-2.8	0.8	1.0	0.8	0.9	0.5	-0.0	-0.3	0.7	1.7	-0.4	-0.1	1.4	-0.8	-2.7	-1.5	2.0
Chest pain or discomfort	0.7	1.0	3.1	-0.4	1.0	0.3	0.4	1.4	1.3	-0.3	0.3	0.5	1.8	0.9	-0.6	0.4	-0.6	-1.7	-1.0	1.5
Had major operations	0.6	0.7	2.6	-1.6	0.3	-0.6	-0.3	0.1	0.5	-1.0	-0.6	1.5	0.6	-0.6	0.8	-0.0	-0.6	-0.4	1.6	0.5
Age at last live birth	0.5	0.7	2.2	-1.0	-1.1	0.6	-1.0	-0.0	0.2	-0.9	1.0	0.7	-0.5	1.5	-0.2	0.0	1.1	0.5	-1.4	-0.0
Family relationship satisfaction	0.4	0.5	3.1	-1.1	0.9	0.8	-0.1	-0.7	0.1	-1.8	-0.3	0.7	-0.1	0.2	0.6	-0.7	-0.3	-0.9	-0.7	0.2
Leg pain on walking	0.6	0.8	3.3	0.2	0.5	0.6	1.3	0.4	0.1	-0.9	0.4	-0.1	0.9	-0.0	1.3	1.8	1.3	-1.0	0.4	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	4.2	-2.1	-0.8	0.1	-1.3	0.4	0.3	0.6	-0.5	0.6	-0.4	-0.2	-0.9	-1.1	-1.2	0.4	1.8	-1.0
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.8	-0.1	-0.6	1.4	-0.8	0.5	-0.1	1.3	0.1	-0.6	0.5	0.3	0.1	1.3	0.6	-0.7	-1.1	0.9
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	6.8	1.0	1.6	-0.3	1.2	-1.2	-0.7	-0.1	-0.9	-0.4	-0.7	-1.2	2.6	-0.7	-0.1	0.2	1.6	-0.9
Medication: Aspirin	0.9	1.2	3.8	0.9	0.3	-0.3	0.1	-1.3	-2.0	-0.0	-1.2	-1.3	-1.4	-1.7	1.4	-0.9	0.7	0.2	0.9	-1.0
Supplements: Vitamin C	0.6	0.7	3.7	1.0	-1.9	-0.4	-0.6	-0.4	-0.6	0.6	0.4	-0.1	-0.7	0.8	-0.9	0.6	1.3	0.2	-0.5	0.7
Knee pain experienced in last month	0.5	0.8	2.5	1.0	0.8	0.9	1.4	-0.4	0.5	-1.4	0.8	1.6	0.8	-0.9	-0.1	0.4	0.7	0.3	-0.7	0.5
Hypertension (Self-reported)	0.6	1.8	7.5	1.8	-0.2	0.6	1.0	-2.7	-2.6	0.0	-1.2	-0.3	-1.4	-1.2	1.1	-0.3	1.1	0.3	-1.4	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	2.2	-0.4	0.1	-0.4	0.3	-0.6	-0.2	-0.8	-0.1	1.1	-0.2	0.5	-1.5	-0.4	0.1	-0.0	-0.1	-0.1
Illnesses of father: Heart disease	2.8	3.9	11.0	-0.0	-0.3	0.1	-1.4	-1.8	-2.5	0.3	-3.1	-2.7	-2.9	-1.2	0.3	-3.3	-2.4	0.1	0.9	-3.3
Illnesses of siblings: Diabetes	1.4	1.7	4.1	-0.7	-1.9	-1.0	-0.5	-1.6	-2.0	-0.8	-1.5	-0.8	-1.2	-1.6	-1.8	-1.2	-0.7	-0.1	-1.3	-1.7
Smoking status: Previous	0.9	1.3	8.4	-2.2	-0.1	-0.1	-0.2	-0.2	-0.6	0.1	-0.8	-0.9	1.4	0.1	-0.1	0.4	-1.2	-2.9	-0.4	1.8
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.6	0.1	-1.1	0.6	-0.5	0.2	0.1	1.1	0.9	0.3	0.1	0.7	-1.1	-0.0	0.5	1.3	0.5	-0.1
Whole body fat-free mass	0.1	0.3	1.0	0.5	0.5	0.5	0.7	0.7	0.5	0.3	0.6	-1.0	0.5	-0.3	0.9	0.4	0.3	0.3	-0.4	0.1
Leg fat-free mass (right)	0.1	0.3	2.2	0.3	0.5	0.1	0.9	0.5	0.6	0.3	0.4	-0.9	0.8	-0.5	1.5	0.2	-0.1	0.1	-0.1	-0.0
Arm fat percentage (left)	0.3	1.3	6.0	-1.1	1.7	-1.4	1.5	-0.7	-0.2	-0.1	-0.9	0.4	0.9	-2.5	1.7	-0.3	-1.1	-1.0	-0.3	0.1
Average weekly red wine intake	0.5	0.7	6.1	0.8	2.5	0.2	0.6	-0.7	-0.8	0.2	-0.5	-0.5	-0.3	0.2	1.1	0.6	0.5	-0.3	-0.5	1.1
Handedness (chirality/laterality): Left-handed	1.4	1.7	5.1	-0.0	-0.4	1.1	-0.9	-1.9	-2.0	-0.7	-1.9	-0.5	-1.9	-0.3	0.1	-2.3	-0.6	-0.4	0.1	-2.3
Mood swings	1.2	2.2	7.6	-2.8	-0.6	0.4	0.4	-2.5	-2.2	-0.6	-2.2	-0.1	-1.2	-0.9	-0.5	-2.3	-1.7	-0.4	0.5	-1.1
Loneliness, isolation	0.8	1.1	11.1	0.4	0.1	-0.5	1.2	0.0	-0.8	1.1	-0.2	-1.1	0.1	-0.2	-0.8	-0.4	0.8	-1.1	-3.3	-0.5
Long-standing illness, disability or infirmity	0.9	1.3	4.2	0.4	0.9	-1.2	0.8	-1.7	-1.9	0.2	-1.4	-1.9	-0.9	-2.0	0.9	-0.9	-0.4	-0.3	-0.5	-0.8
Ever had bowel cancer screening	1.1	1.3	12.6	1.1	0.4	0.8	1.5	0.6	0.2	0.2	0.1	-1.3	1.4	-0.2	-0.3	0.0	0.5	-1.1	-3.5	0.2
Diabetes diagnosed by doctor	1.8	2.9	10.0	0.9	0.9	-0.2	-0.3	-2.3	-3.1	0.2	-2.2	-3.2	-2.2	-1.7	1.3	-1.7	-0.3	1.0	1.1	-1.8
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	8.1	0.7	2.2	0.4	2.9	-0.8	-0.8	-0.1	0.0	-0.1	0.6	-1.0	2.0	1.3	1.5	0.4	-0.1	0.7
Friendships satisfaction	0.8	1.0	4.3	-2.1	0.9	1.4	-0.2	-1.2	-0.6	-2.0	-0.9	1.0	-0.3	-1.2	0.8	-0.2	-0.7	-0.5	0.1	0.1
Qualifications: nursing, teaching	0.8	1.2	6.2	0.3	1.0	2.5	0.1	-1.1	-1.4	-0.5	-1.3	-1.6	-1.1	-0.8	0.1	-0.3	-0.4	-0.2	1.2	-1.4
Commuting to job workplace: Walk	0.9	0.9	7.5	0.9	2.7	0.7	1.6	-0.1	-0.0	0.3	-0.0	0.2	-0.1	0.3	1.3	0.6	-0.1	1.0	0.8	0.7
Eye problems/disorders: Cataract	0.8	0.9	3.6	0.8	1.2	-1.1	0.9	-0.8	-0.9	1.0	-0.6	-0.9	-0.4	-1.8	0.3	-0.7	0.1	-0.3	-1.9	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.6	0.3	-0.3	1.3	-0.6	0.1	-0.3	0.7	-0.2	0.2	-0.6	0.4	0.4	-0.3	0.2	0.9	-0.2	-0.0
Medication for cholesterol	1.7	2.5	10.6	-0.7	1.3	2.0	0.0	2.6	2.4	1.7	1.2	1.0	1.5	3.3	0.8	0.8	-1.1	-0.6	0.5	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.8	-1.0	1.1	-1.3	1.7	0.7	0.4	1.3	0.0	-0.6	1.5	-0.4	0.1	0.1	-0.2	-0.7	-0.0	1.1
Back pain experienced in last month	1.6	2.4	5.9	-1.7	1.6	1.1	2.2	-2.4	-2.1	0.1	-2.1	0.0	-0.2	-2.0	2.0	-0.7	-0.6	-1.7	-1.0	-0.7
Mineral and other dietary supplements	0.7	0.9	8.9	0.1	0.9	-0.8	-0.3	1.0	0.6	3.0	0.4	-0.4	-0.1	0.9	0.4	-0.4	-0.2	0.9	0.1	-0.9
Breast cancer (self-reported)	1.2	1.4	6.6	0.8	-0.4	2.1	-1.2	1.1	-0.3	1.7	0.3	-1.2	-0.2	2.6	-1.4	-0.1	1.1	-0.7	-1.0	-0.6
Asthma (self-reported)	0.2	0.4	1.0	0.1	0.8	0.8	0.2	-1.0	-0.9	0.4	-0.9	-0.6	-0.2	0.7	0.6	-0.7	-0.8	-0.5	-0.1	-0.1
Osteoporosis (self-reported)	1.2	1.4	5.5	0.3	0.2	-0.6	0.8	1.1	0.9	-0.4	1.2	0.5	1.5	2.0	-0.3	2.3	1.1	-1.1	-1.0	2.0
Osteoarthritis (self-reported)	1.3	1.7	11.3	1.0	1.1	1.5	0.5	-0.6	-1.1	1.1	-1.1	-1.4	0.3	-1.0	-0.5	-0.2	-0.6	-2.3	-3.4	-0.1
Medication: Aspirin	0.9	1.2	4.5	0.9	0.4	0.1	0.1	-1.6	-2.1	-0.3	-1.3	-1.2	-1.4	-1.8	1.4	-0.8	0.6	0.1	0.4	-0.9
Medication: Gliclazide	2.0	2.2	7.5	0.6	1.2	-0.6	-1.8	-1.3	-2.3	0.9	-1.7	-1.3	-2.7	-1.7	-0.3	-1.8	-0.5	1.7	-1.0	-1.6
Illnesses of father: None of the above (group 1)	0.3	0.4	1.4	-0.4	0.8	0.3	0.7	0.1	0.4	-0.5	-0.1	-0.1	1.1	0.5	-0.5	-0.1	-1.0	-1.2	-0.7	0.7
Smoking status: Current	0.4	0.6	3.4	-1.0	-0.1	-0.9	1.9	0.6	1.1	0.5	0.6	0.6	0.6	-1.0	-0.0	-0.3	-0.5	0.8	0.3	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.5	17.0	1.9	3.7	0.7	2.7	0.9	1.5	0.6	1.0	0.3	1.6	-0.0	4.1	2.1	0.3	0.3	1.5	1.9
Whole body water mass	0.1	0.3	0.9	0.5	0.6	0.5	0.7	0.7	0.5	0.3	0.6	-0.9	0.5	-0.3	1.0	0.5	0.3	0.3	-0.4	0.1
Leg predicted mass (right)	0.1	0.4	2.3	0.2	0.5	0.1	0.9	0.6	0.7	0.3	0.4	-0.9	0.8	-0.5	1.5	0.2	-0.1	0.1	-0.1	0.0
Arm fat mass (left)	0.2	0.9	5.0	-0.9	1.3	-1.0	1.4	-0.3	-0.0	0.2	-0.5	0.0	0.9	-2.2	1.3	-0.1	-0.7	-0.7	-0.4	0.2
Number of self-reported non-cancer illnesses	0.5	0.8	2.9	0.2	0.9	0.7	1.1	-1.6	-1.7	0.2	-1.0	-0.6	-0.2	-1.2	0.2	0.1	0.6	-0.7	-1.4	0.0
Average weekly champagne plus white wine intake	0.3	0.4	2.6	0.1	-0.9	0.3	-0.2	-0.0	0.1	-0.3	-0.3	-0.4	0.4	1.1	1.2	0.2	-0.4	-1.6	0.2	0.5
Miserableness	0.4	0.6	4.2	-2.0	-0.6	-0.8	1.5	-0.7	-0.8	-0.1	-0.6	0.2	0.5	-0.7	0.2	0.1	-0.1	-0.6	-0.4	0.2
Guilty feelings	1.8	2.7	9.2	0.1	1.1	2.2	1.1	-2.6	-2.6	-0.1	-3.0	-1.1	-1.5	-1.2	1.1	-1.3	-1.9	-1.5	-0.7	-0.9
Wears glasses or contact lenses	1.6	1.9	7.9	0.2	2.5	2.8	1.0	-0.9	-1.3	0.8	-1.3	-0.4	-0.2	0.6	-0.0	0.1	-0.5	-2.2	-2.4	0.3
Ever taken oral contraceptive pill	0.9	1.0	5.8	0.4	0.6	0.6	-0.3	0.9	0.4	0.9	0.2	0.7	0.8	1.1	-0.2	2.4	0.5	-0.7	-1.4	1.7
Hearing aid user	0.5	0.6	2.5	0.8	1.5	1.6	0.4	0.1	-0.1	-1.2	-0.4	-0.3	-0.5	-0.5	1.3	-0.0	-0.0	0.2	-0.4	-0.5
Mother’s age at death	0.5	0.7	4.6	0.7	2.1	0.7	0.6	-0.7	-0.1	0.6	0.0	0.6	-0.2	-0.8	1.1	-0.2	0.4	0.8	0.9	-0.8
Financial situation satisfaction	1.0	1.2	7.0	-2.7	-0.4	-1.4	-0.4	0.1	0.7	-1.7	0.3	1.7	0.8	-0.0	-1.0	-0.3	-0.7	-0.9	-0.2	1.3
Tinnitus: Yes, now most or all of the time	1.0	1.2	4.1	-0.8	0.1	1.3	0.2	-0.6	-1.5	1.4	-1.8	-2.0	-0.4	0.0	0.4	-1.1	-0.8	-1.7	-0.8	-0.6
Commuting to job workplace: Public transport	2.7	3.3	8.7	-0.4	1.9	-1.3	2.2	-2.4	-1.5	-1.8	-1.8	-0.3	-1.5	-2.4	2.9	-1.4	-1.2	0.7	2.4	-2.2
Eye problems/disorders: Glaucoma	1.7	2.0	5.5	-0.8	-0.1	-0.8	-1.1	-1.4	-2.1	0.2	-2.1	-1.9	-2.4	-0.2	0.0	-1.3	-1.6	0.9	1.8	-1.6
Medication: Blood pressure	0.4	0.7	3.9	1.1	-0.4	-0.3	1.1	-1.4	-1.1	-0.1	-0.2	0.1	-0.1	-2.0	-0.1	0.3	1.3	0.2	-0.9	0.1
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.4	1.4	0.3	1.5	1.2	-0.3	-0.3	-0.3	-0.5	-0.2	0.5	-1.1	1.5	0.2	0.1	-0.8	-1.1	0.2
Supplements: Fish oil (including cod liver oil)	0.5	0.6	3.8	0.5	-0.1	1.6	1.2	-0.8	-0.5	-1.9	-0.6	0.4	-0.2	-0.2	0.4	0.3	0.1	-0.7	0.0	0.3
High cholesterol (Self-reported)	0.9	1.5	3.6	1.8	0.5	-0.8	-0.5	-1.6	-1.7	-0.7	-0.9	-1.2	-1.4	-1.9	0.8	-0.8	0.6	1.9	1.4	-0.8
Medication: Bendroflumethiazide	0.5	0.8	3.2	-0.3	-1.1	-1.2	1.6	-1.2	-0.8	-1.8	-0.0	-0.0	0.2	-1.3	0.1	-0.2	1.0	-0.4	-0.2	0.0
Medication: Paracetamol	2.2	3.4	14.7	-2.2	1.3	0.9	2.7	0.6	0.7	0.2	-0.2	0.9	3.2	-0.5	0.6	1.5	-0.8	-3.8	-2.7	2.4
Medication: Lisinopril	1.1	1.4	3.6	-1.9	-0.2	-1.2	0.6	-1.4	-1.5	0.9	-1.6	-1.9	-0.5	-1.4	-0.3	-1.2	-1.5	-1.2	0.2	-0.6
Medication: Atorvastatin	1.2	1.4	5.7	1.5	1.6	-1.1	2.4	-0.4	0.1	-0.9	0.7	0.9	0.5	-1.5	1.3	1.4	1.2	1.1	0.1	1.0
Illnesses of father: High blood pressure	0.6	0.8	2.6	-0.3	0.7	-1.2	1.3	-0.4	0.6	0.3	1.2	1.6	0.8	0.3	0.9	1.0	1.0	0.8	0.3	0.6
Alcohol drinker status: Never	2.4	2.8	7.7	0.8	-0.0	-1.2	0.2	-0.8	-1.5	1.0	-2.3	-2.8	-1.7	-0.5	2.6	-1.8	-1.7	0.3	2.5	-2.6
Ever smoked	0.9	1.5	5.9	-2.1	0.4	0.1	1.8	0.7	0.7	1.2	0.3	-0.2	2.4	0.4	0.5	0.4	-0.7	-2.2	-0.5	2.0
Basal metabolic rate	0.0	0.3	0.9	0.2	0.5	0.2	0.7	0.5	0.3	0.3	0.3	-1.0	0.5	-0.8	1.0	0.2	-0.0	0.1	-0.3	-0.0
Leg fat percentage (left)	0.3	0.9	4.8	-1.8	0.5	-1.6	1.0	-0.4	-0.3	-0.3	-0.7	0.1	0.8	-2.2	0.2	-0.0	-0.8	-1.2	0.1	0.4
Arm fat-free mass (left)	0.1	0.3	1.1	0.3	0.2	0.6	0.8	0.7	0.4	0.3	0.6	-1.1	0.5	-0.4	0.2	0.3	0.3	0.2	-0.7	-0.1
Number of operations (self-reported)	0.3	0.5	1.7	-1.3	0.0	-0.7	0.5	-0.1	-0.2	-0.7	-0.6	-0.8	0.6	-1.3	1.0	-0.4	-0.1	-1.1	0.2	0.2
Average weekly beer plus cider intake	1.1	1.6	8.4	0.3	-2.9	0.8	-0.5	1.3	1.9	-1.0	2.0	1.7	1.0	0.1	0.3	0.1	1.4	1.1	0.9	0.1
Irritability	3.1	5.2	13.2	-1.7	-1.0	-0.3	0.5	-3.5	-3.6	-1.3	-2.9	-2.1	-3.5	-2.3	0.7	-3.0	-1.3	0.4	1.6	-3.6
Risk taking	0.8	1.2	4.4	1.0	-1.0	-1.3	-0.3	-1.0	-0.7	-0.8	-0.6	0.4	-1.4	-0.6	0.5	-1.1	-0.1	2.1	1.7	-1.6
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.7	0.0	1.1	1.1	1.3	-1.0	-0.9	-0.5	-1.1	-0.2	-0.3	-0.2	1.2	0.2	-0.3	0.0	-0.6	-0.4
Fractured/broken bones in last 5 years	1.3	1.7	8.8	0.1	-1.6	-1.2	0.7	-0.2	0.8	-3.0	1.5	1.5	0.2	-0.9	-0.4	0.7	1.0	2.0	1.8	0.2
Age started oral contraceptive pill	0.3	0.4	1.6	-0.1	-0.4	-0.2	-1.2	0.7	0.4	-0.5	0.2	-0.9	0.0	1.3	-0.9	-0.1	-0.2	-0.4	0.7	-0.1
Diastolic blood pressure, automated reading	0.2	0.5	1.8	0.1	-0.1	1.3	0.1	-0.5	0.0	-1.3	0.8	0.8	0.8	-1.0	-0.8	0.2	0.7	0.1	-0.3	0.2
Ever depressed for a whole week	1.5	1.8	6.1	-1.5	0.7	1.7	1.8	1.2	0.9	0.4	-1.0	-1.4	1.4	0.8	0.8	-1.1	-2.5	-2.3	0.7	0.1
Unable to work because of sickness or disability	0.4	0.5	2.1	0.5	-0.7	-0.5	0.3	0.4	0.1	1.1	0.6	-0.4	0.8	0.4	-0.7	1.0	0.9	-0.4	0.1	1.5
Commuting to job workplace: Cycle	0.7	0.8	3.4	-0.1	1.4	-1.4	0.9	0.1	0.3	-1.1	-0.5	0.6	0.7	0.1	1.9	0.3	-0.8	-1.1	-0.2	1.3
Myopia	0.5	0.7	2.3	-0.4	-0.1	1.5	0.9	0.6	0.1	-0.5	0.0	-0.1	1.0	0.9	-0.4	1.3	0.7	-1.5	-0.4	1.0
Vascular/heart problems diagnosed by doctor	0.8	2.2	8.8	-1.4	0.1	-0.2	-0.5	2.9	3.0	0.4	1.7	0.9	1.8	2.0	-1.3	0.8	-0.8	-0.5	0.3	1.7
Cholesterol lowering medication	1.1	1.6	4.8	0.7	-0.6	-1.8	0.0	-1.7	-2.2	-1.1	-0.9	-1.5	-1.7	-2.1	-0.9	-0.3	1.3	1.0	-0.2	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	4.3	-0.6	0.7	-0.1	0.9	-0.1	0.1	-0.6	-0.6	0.6	1.3	-0.9	0.1	0.3	-0.7	-2.1	0.4	0.7
Pain experienced in last month	1.5	2.6	8.3	0.3	-2.2	-2.9	-2.1	2.0	1.3	1.1	1.5	-0.9	-0.4	1.9	-2.4	0.2	0.5	1.7	1.8	-0.3
Supplements: Calcium	1.4	1.6	4.6	1.8	-0.2	0.0	-0.3	1.3	0.9	0.7	1.6	0.1	1.2	1.3	-0.5	2.1	1.9	0.1	-1.3	2.0
Basal cell carcinoma (self-reported)	0.5	0.6	1.3	0.7	0.8	0.2	-0.1	-1.0	-0.7	-0.8	-1.1	-0.9	-0.6	-1.1	0.6	-1.1	-1.0	-0.3	-0.3	-0.7
Heart attack/myocardial infarction (self-reported)	0.8	1.1	5.1	0.9	1.5	-0.8	0.5	1.6	0.6	2.3	0.2	-0.4	0.9	0.2	1.3	1.1	0.5	-0.5	-1.0	1.0
Deep venous thrombosis (DVT) (self-reported)	4.1	5.3	12.8	0.5	2.7	1.3	0.5	-3.4	-3.1	0.0	-3.6	-2.1	-2.8	-3.4	2.9	-2.4	-1.9	0.0	-0.2	-2.5
Heart disease (siblings)	2.0	2.5	8.8	1.9	2.7	3.0	2.7	0.3	1.0	-0.2	0.2	0.9	2.1	0.5	0.8	-0.0	-0.1	-1.9	-1.9	1.0
Alcohol drinker status: Previous	1.3	1.5	4.4	-0.8	-0.2	-0.2	-1.8	-2.0	-2.1	-1.2	-1.7	-0.9	-1.6	-1.4	0.2	-0.8	-0.6	-0.6	-0.4	-1.1
Pack years of smoking	0.3	0.5	3.7	-0.8	-0.0	0.5	1.1	0.6	-0.1	1.9	-0.0	0.1	0.2	0.6	-0.9	0.5	0.3	0.6	-0.7	-0.0
Impedance of whole body	0.2	0.9	3.3	-0.5	-0.4	-1.8	-1.5	-0.3	-0.2	-0.5	-0.9	0.2	-0.5	-0.5	-0.7	-1.4	-1.6	-1.0	1.0	-0.5
Leg fat mass (left)	0.2	0.8	5.2	-1.3	0.7	-1.0	1.2	-0.2	0.0	-0.3	-0.5	-0.2	0.8	-2.3	0.6	-0.4	-0.9	-0.8	0.1	-0.0
Arm predicted mass (left)	0.1	0.3	0.8	-0.0	0.1	0.7	0.9	0.9	0.5	0.2	0.7	-0.8	0.6	-0.2	0.3	0.6	0.4	0.3	-0.3	0.2