Hub : Genes

TMEM156

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 METSIM Adipose 0.0421 0.0177 1.4e-03 0.048 0.025 0.043 0.033 0.044 8.4e-08 9.8e-05 4.3e-07 8.3e-06 2.8e-07
2 NTR Blood 0.0166 0.0081 4.6e-03 0.008 0.005 0.008 0.006 0.013 1.1e-03 6.7e-03 7.8e-04 2.9e-03 3.7e-05
3 ROSMAP Brain Pre-frontal Cortex 0.2056 0.0426 1.5e-12 0.160 0.130 0.162 0.157 0.157 4.2e-20 2.2e-16 2.6e-20 1.1e-19 1.0e-19
4 YFS Blood 0.0872 0.0229 1.4e-07 0.032 0.028 0.044 0.039 0.039 8.1e-11 1.8e-09 3.8e-14 9.1e-13 7.5e-13
5 TCGA Bladder Urothelial Carcinoma 0.0590 0.0270 2.7e-03 0.061 0.035 0.033 NA 0.056 7.5e-06 5.4e-04 7.6e-04 NA 1.5e-05
6 TCGA Breast Invasive Carcinoma 0.0227 0.0098 1.6e-04 0.035 0.017 0.024 NA 0.028 7.9e-08 1.6e-04 9.9e-06 NA 1.8e-06
7 TCGA Colon Adenocarcinoma 0.1710 0.0560 1.1e-05 0.056 0.088 0.089 NA 0.088 3.7e-04 8.5e-06 7.8e-06 NA 9.4e-06
8 TCGA Head and Neck Squamous Cell Carcinoma 0.0669 0.0266 5.0e-06 0.040 0.043 0.031 NA 0.040 2.4e-05 1.2e-05 1.8e-04 NA 2.6e-05
9 TCGA Kidney Renal Papillary Cell Carcinoma 0.0690 0.0350 8.7e-03 0.021 0.044 0.022 NA 0.019 2.2e-02 1.4e-03 2.0e-02 NA 2.8e-02
10 TCGA Brain Lower Grade Glioma 0.1063 0.0306 3.5e-10 0.138 0.082 0.107 NA 0.125 2.2e-15 1.3e-09 3.6e-12 NA 4.8e-14
11 TCGA Lung Adenocarcinoma 0.0467 0.0216 9.2e-04 0.026 0.023 0.016 NA 0.020 4.8e-04 9.6e-04 5.4e-03 NA 1.9e-03
12 TCGA Lung Squamous Cell Carcinoma 0.0734 0.0277 5.9e-06 0.041 0.037 0.028 NA 0.036 1.9e-05 4.3e-05 3.1e-04 NA 5.2e-05
13 TCGA Stomach Adenocarcinoma 0.0860 0.0360 2.8e-04 0.021 0.038 0.022 NA 0.020 1.0e-02 9.7e-04 9.0e-03 NA 1.4e-02
14 TCGA Thyroid Carcinoma 0.0720 0.0340 1.2e-03 0.014 0.033 0.016 NA 0.025 1.4e-02 3.5e-04 9.7e-03 NA 1.7e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 0.9 1.5 3.2 1.6 0.9 -1.8 0.5 1.6 1.5 1.4 0.7 0.8 1.4 1.2 1.3 1.2 -0.3
Bipolar Disorder or Schizophrenia 0.4 1.1 2.6 1.6 1.1 -1.4 0.4 0.2 1.5 0.2 0.2 -1.6 1.5 1.1 0.4 -0.3 -0.6
Depressed Affect (Nagel 2018) 0.2 0.5 2.3 0.1 0.1 0.0 -0.2 1.0 -0.1 1.3 0.1 1.5 -0.1 -0.1 -0.6 0.3 -1.1
Depression (Nagel 2018) 0.4 0.6 2.1 0.7 0.6 -0.7 -0.5 0.8 0.7 1.4 0.5 1.2 0.7 0.6 1.2 0.1 -0.2
Intelligence (Savage-Jansen 2018) 0.7 2.3 4.3 -1.6 -2.1 0.9 -1.0 -1.6 -1.7 -2.0 -1.4 -0.9 -1.6 -1.9 -1.4 -1.5 -0.6
Neuroticism (Nagel 2018) 0.5 1.1 2.8 -1.0 -1.2 1.3 -1.2 -0.4 -1.1 0.3 -0.9 0.4 -1.1 -0.8 -1.2 -1.0 -1.7
Schizophrenia (2018) 0.5 1.0 7.3 0.8 0.6 -0.3 0.0 -1.0 0.8 -0.8 -0.3 -2.7 0.8 0.4 -0.5 -1.3 -0.5
Schizophrenia vs Biploar Disorder 1.4 1.8 7.9 -0.8 -1.2 1.5 -1.2 -1.8 -0.8 -1.3 -1.1 -2.8 -0.8 -0.9 -0.9 -1.7 0.3
Worry (Nagel 2018) 1.2 2.5 5.1 -1.5 -1.4 1.8 -1.5 -1.5 -1.4 -0.1 -1.9 -1.0 -1.3 -1.5 -1.7 -2.2 -2.3
Alzheimer’s Disease (in mother) 0.1 0.1 0.8 -0.4 0.3 -0.3 -0.9 0.0 -0.3 -0.3 0.3 0.2 -0.3 0.3 0.3 -0.2 0.4
Alzheimer’s Disease (in father) 0.2 0.3 1.2 0.3 0.2 0.3 0.6 0.8 0.3 0.5 0.1 0.3 0.3 -1.1 -0.5 0.4 -0.6
Alzheimer’s Disease (including proxy) 0.1 0.2 0.6 0.3 0.7 -0.5 0.2 0.5 0.5 -0.2 0.6 -0.1 0.5 0.4 0.1 0.5 0.6
Crohns Disease (2017) 5.0 10.9 23.0 -3.6 -3.4 3.6 -4.8 -3.4 -3.6 -3.1 -3.2 -2.0 -3.6 -2.9 -2.5 -3.6 -2.0
Irritable Bowel Disease (IBD) 3.0 7.2 14.3 -2.9 -2.7 3.0 -3.8 -2.2 -2.9 -2.6 -2.6 -1.7 -2.9 -2.1 -2.1 -3.3 -2.0
Ulcerative Colitis (UC) 0.8 1.6 3.4 -1.1 -1.2 1.2 -1.2 -0.4 -1.2 -1.2 -1.4 -1.2 -1.2 -0.5 -1.3 -1.8 -1.7
Major Depression (MDD) 0.5 0.6 1.3 0.9 1.0 -1.1 0.5 0.9 1.0 0.9 0.2 -0.3 1.0 0.8 -0.0 0.2 -0.4
Reaction Time 0.5 0.9 4.5 0.5 0.7 -0.9 0.2 1.7 0.3 0.9 0.5 0.8 0.3 1.5 0.4 2.1 0.0
Verbal and Numeric Reasoning (VNR) 1.0 2.4 6.6 -1.4 -2.0 1.0 -0.8 -2.6 -1.6 -1.8 -0.7 -0.4 -1.6 -2.2 -1.5 -1.7 -0.8
Breast Cancer 0.2 0.4 2.3 -0.3 0.1 0.2 -0.2 0.4 -0.3 -0.1 0.3 0.1 -0.3 1.0 -0.2 1.5 1.2
Ovarian Cancer 0.4 0.6 4.2 -0.5 0.4 0.1 0.0 0.5 -0.5 0.1 0.1 2.0 -0.5 -1.2 -0.7 0.5 -0.6
Prostate Cancer 0.9 1.2 4.0 -1.2 -1.4 0.7 -1.4 -1.2 -1.2 -2.0 -0.7 -0.8 -1.2 -0.5 -0.2 -1.2 -0.1
Age at First Birth 0.2 0.3 1.6 -0.8 -1.3 0.3 -0.4 -0.4 -0.8 0.1 -0.2 0.6 -0.7 -0.1 0.5 -0.6 -0.2
Bipolar Disorder (2011) 0.6 0.6 1.9 1.1 0.4 -1.0 1.4 -0.1 0.9 0.7 -0.1 0.3 0.9 -0.3 -0.2 -0.1 -1.1
Body Mass Index (BMI) (2010) 0.1 0.1 0.4 -0.3 -0.2 0.6 0.3 -0.3 -0.3 0.6 0.0 -0.3 -0.2 0.2 -0.1 -0.0 -0.3
Coronary Artery Disease (CAD) 2.0 2.4 4.4 -1.6 -1.2 1.1 -0.2 -1.4 -1.8 -1.2 -2.0 -0.9 -1.8 -1.9 -2.1 -1.9 -1.5
Crohns Disease (2012) 2.0 3.1 6.2 -1.7 -1.8 1.3 -2.5 -1.7 -1.7 -1.3 -2.1 -0.4 -1.7 -2.3 -1.7 -1.6 -2.0
Mean Putamen Volume 0.8 0.9 4.2 -0.7 -1.1 0.9 -0.6 -1.0 -0.8 -0.8 -0.8 -0.3 -0.7 -2.1 -0.8 -1.1 -0.0
Fasting Glucose 0.5 0.6 1.5 0.7 1.0 -0.9 0.7 0.5 0.7 1.2 0.7 0.9 0.7 0.3 1.0 0.7 -0.3
HbA1C 0.9 1.0 4.1 -0.5 -1.2 0.4 -0.3 -0.0 -0.5 0.5 -1.5 -1.4 -0.5 -0.1 -1.9 -0.5 -2.0
HDL Cholesterol 0.7 1.2 4.2 1.2 1.6 -1.0 1.0 0.8 0.8 -0.0 1.1 -0.3 0.8 1.1 1.4 0.9 2.0
LDL Cholesterol 0.1 0.2 0.8 -0.4 -0.3 0.5 -0.2 -0.9 -0.7 0.3 -0.4 0.2 -0.6 -0.3 0.3 -0.7 0.2
Lupus 0.2 0.3 1.6 -0.6 -0.7 0.3 -0.6 -0.2 -0.4 -0.4 0.2 -0.1 -0.5 -0.1 0.4 0.4 1.3
Neuroticism (2016) 0.2 0.3 1.1 -0.1 0.3 0.1 -0.7 0.7 -0.0 0.5 -0.5 -0.7 -0.0 1.1 -0.1 -0.4 -1.0
Primary Biliary Cirrhosis 0.5 0.7 1.5 0.9 1.1 -0.9 0.0 1.0 1.0 0.7 0.4 1.2 1.0 0.6 0.5 1.0 0.0
Rheumatoid Arthritis 2.4 3.4 8.8 2.1 2.2 -1.9 1.8 0.8 2.2 1.7 1.6 -0.2 2.2 3.0 1.9 1.4 0.8
Schizophrenia (2014) 0.3 0.7 4.1 0.9 0.8 -0.8 -0.4 -0.1 0.9 -0.4 -0.4 -2.0 0.9 0.6 -0.2 -0.8 -0.4
Triglycerides 1.5 2.4 5.2 1.7 1.3 -1.3 1.7 0.9 1.3 2.2 1.7 2.3 1.4 1.3 1.9 1.3 0.9
Type 2 Diabetes (T2D) (2012) 2.1 2.4 6.2 -2.1 -1.5 2.1 -1.2 -0.6 -2.5 0.2 -1.4 -1.2 -2.4 -1.0 -1.4 -0.4 -1.6
Ulcerative Colitis 0.4 0.6 2.3 0.4 0.0 -0.3 0.0 1.3 0.4 0.7 -1.2 -0.8 0.4 0.5 -0.2 -0.7 -1.5
Blood Eosinophil Count 7.5 57.7 102.0 8.8 8.1 -7.3 9.3 4.4 8.8 10.1 8.1 7.5 8.8 5.8 6.7 6.8 0.1
Blood Platelet Count 0.2 2.2 9.9 0.0 -0.4 -0.3 -2.4 0.0 0.0 -2.1 -1.1 -3.1 -0.1 1.4 0.1 -1.7 2.1
Blood Red Count 0.6 5.7 31.8 -1.4 -2.2 1.4 1.6 -2.8 -1.3 1.0 -0.5 1.6 -1.2 -3.9 -2.5 -1.2 -5.6
Blood White Count 2.2 16.6 25.3 4.6 5.0 -5.0 4.1 3.1 4.7 3.3 4.2 1.8 4.6 4.9 3.8 3.6 3.0
Heel T-Score 0.1 0.4 1.1 -0.5 0.2 0.6 0.7 -1.0 -0.6 -0.7 0.2 -0.2 -0.6 -0.2 -0.8 -1.1 -0.8
BMI 0.5 2.9 7.7 1.6 1.6 -0.4 2.8 -0.2 1.5 1.6 2.8 2.7 1.5 -0.0 1.7 0.9 1.1
Height 0.6 11.6 40.2 -2.8 -3.5 2.2 -0.8 -3.4 -2.8 -1.4 -3.5 0.9 -2.8 -6.3 -3.8 -2.8 -5.7
Waist Hip Ratio (WHR) 1.7 7.5 14.8 3.1 3.9 -2.8 2.7 1.6 3.1 1.8 3.1 1.2 2.9 3.6 2.9 2.2 2.4
Systolic Blood Pressure 0.3 1.7 3.1 -1.6 -0.4 1.1 -0.4 -1.5 -1.5 -0.8 -1.4 0.1 -1.6 -1.3 -1.4 -1.8 -1.7
Smoking Status 0.1 0.3 1.6 -0.1 0.0 -0.0 -1.3 -0.1 -0.1 0.0 0.2 -0.5 -0.1 -0.0 1.2 -0.2 1.1
Allergy or Eczema 0.9 2.4 8.5 0.3 1.0 -2.8 -2.0 0.7 0.4 -2.2 -2.0 -1.2 0.3 2.9 -0.6 0.5 0.1
Cardiovascular Disease 0.2 0.5 2.2 -0.5 -0.0 0.1 0.1 -0.1 -0.7 0.4 -0.9 0.4 -0.7 -0.9 -1.1 -0.9 -1.5
Hypothyroidism (self reported) 1.7 3.9 8.2 2.4 2.0 -0.9 2.9 -0.1 2.5 2.0 2.7 2.2 2.5 0.5 2.0 1.4 1.2
Respiratory disease 0.3 0.6 2.8 -0.5 0.1 -0.0 -1.5 -0.0 -0.7 -1.7 -0.6 -0.8 -0.8 0.8 -0.3 -0.7 -0.3
Type 2 Diabetes (T2D) (2018) 0.3 0.6 3.7 0.5 1.0 0.1 0.7 0.4 0.5 -0.2 0.8 0.5 0.6 -0.6 0.8 0.3 1.9
Lung FEV1/FVC ratio 0.4 2.3 6.3 -1.2 -1.6 1.7 -1.4 -2.1 -1.2 -1.8 -0.5 -0.5 -1.2 -2.5 -1.5 -1.0 -1.6
Lung FVC 0.5 2.5 4.6 -1.8 -2.0 2.1 -1.5 0.0 -2.0 -1.3 -1.8 -2.1 -2.0 -0.8 -1.2 -1.3 -0.0
Neuroticism 0.1 0.2 1.0 -0.1 -0.2 0.6 -0.6 0.0 -0.2 0.9 -0.2 0.2 -0.2 -0.3 -0.4 -0.6 -1.0
Chronotype (morning person) 0.2 0.6 2.8 -0.2 -0.6 0.4 0.6 -1.7 -0.3 -1.2 0.1 1.0 -0.4 -1.1 0.1 -0.6 -0.1
Hair Pigment 0.0 0.8 5.2 -0.2 -0.5 0.7 0.5 -0.3 -0.2 1.6 0.2 2.3 -0.1 -1.3 0.3 0.3 -1.1
Tanning 0.1 0.7 3.2 -0.7 -0.3 0.8 -0.7 -0.5 -0.9 -1.5 -0.4 -1.8 -0.9 0.5 0.2 -0.1 0.4
Hand grip strength (left) 0.9 2.4 4.7 2.2 1.3 -1.9 1.2 -0.3 2.2 1.3 1.6 1.9 2.1 0.7 1.4 1.5 0.8
Number of treatments/medications taken 1.1 2.1 4.7 -1.3 -1.1 1.2 -1.7 -0.8 -1.5 -1.4 -1.3 -0.4 -1.5 -1.9 -2.2 -1.6 -1.5
Average weekly spirits intake 2.1 2.6 6.9 -1.5 -1.8 1.4 -0.5 -2.3 -1.5 -2.6 -0.7 -0.4 -1.4 -2.0 -1.2 -2.3 -0.7
Sensitivity / hurt feelings 0.1 0.2 0.8 0.5 -0.0 -0.0 0.2 -0.2 0.3 -0.9 0.1 -0.4 0.3 0.7 -0.7 -0.5 -0.1
Frequency of depressed mood in last 2 weeks 0.3 0.5 1.2 0.9 0.8 -0.7 -0.1 0.7 0.8 1.1 0.4 1.0 0.8 0.6 0.7 0.3 -0.2
Hearing difficulty/problems: Yes 0.2 0.4 1.0 0.5 0.3 -0.7 0.4 0.3 0.9 0.7 -0.4 -1.0 0.9 0.1 -0.1 -0.2 -0.9
Relative age of first facial hair 0.4 0.8 2.5 -0.7 -0.8 0.5 0.0 -1.4 -0.7 -0.9 -0.5 -0.2 -0.7 -1.1 -0.8 -1.0 -1.6
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 2.4 1.4 0.9 -1.3 0.9 0.8 1.2 0.5 0.3 -1.0 1.3 1.5 0.4 0.6 0.1
Ever used hormone-replacement therapy (HRT) 0.1 0.1 0.6 -0.0 -0.4 0.1 -0.3 0.7 0.0 -0.2 0.0 0.4 0.0 0.1 -0.3 -0.1 0.4
Ever had hysterectomy (womb removed) 0.1 0.2 0.8 0.0 -0.2 0.3 -0.7 0.0 -0.0 0.9 -0.1 0.4 0.0 -0.2 0.2 -0.4 -0.6
Systolic blood pressure, automated reading 0.5 1.4 2.8 -1.4 -0.9 1.1 -0.4 -1.7 -1.2 -0.7 -1.2 0.1 -1.3 -1.2 -1.4 -1.6 -1.7
Eye problems/disorders: Diabetes related eye disease 1.8 1.9 5.1 1.0 1.1 -0.6 0.4 2.0 1.0 2.2 1.4 2.2 1.0 0.8 1.6 1.6 1.0
Angina 0.2 0.3 0.9 -0.3 0.5 0.2 -0.7 0.9 -0.5 0.6 -0.1 0.3 -0.5 -0.0 -0.3 0.8 -0.5
Medication for hormone replacement therapy 0.8 0.9 2.6 0.8 0.7 -0.5 -0.1 1.1 0.9 -0.6 -0.2 -1.6 0.9 1.5 0.2 -0.3 1.6
Vitamin and mineral supplements 0.6 0.9 3.3 -0.2 0.4 0.1 0.5 1.2 -0.0 0.4 1.1 1.5 -0.0 0.4 1.5 0.9 1.8
Supplements: Zinc 0.2 0.2 1.3 0.3 -0.1 -0.4 0.1 -0.1 0.2 1.2 0.4 0.2 0.2 0.4 0.1 0.4 -0.4
Medication: Co-codamol 0.2 0.3 1.2 0.2 -0.6 -0.3 -1.1 -0.1 0.1 -0.4 -0.2 -1.0 0.1 0.7 0.6 -0.0 -0.6
Medication: Metformin 0.7 1.0 2.2 -0.9 -0.8 1.2 -1.2 -1.1 -1.0 -1.5 -0.5 -0.7 -1.0 -1.1 -0.6 -0.9 0.8
Diabetes (father) 0.3 0.4 1.9 0.7 1.4 -0.5 0.4 0.2 0.7 0.8 0.4 -0.0 0.7 0.5 0.9 0.2 0.6
Diabetes (mother) 0.5 0.7 2.6 -1.0 -0.3 0.9 -0.2 -1.2 -0.8 -1.6 -0.4 -0.6 -0.8 -0.3 -0.2 -1.0 0.2
Severe depression (siblings) 0.1 0.2 0.5 -0.5 -0.5 0.7 -0.1 0.2 -0.4 -0.2 -0.4 -0.5 -0.4 0.4 0.1 0.1 0.5
Pack years adult smoking proportion 0.6 0.9 3.1 0.6 0.6 -1.1 0.7 1.8 0.7 0.8 0.4 0.4 0.7 1.4 0.6 1.3 -0.5
Impedance of leg (right) 0.2 1.1 2.4 -1.4 -0.1 1.3 -1.1 -0.0 -1.4 -1.2 -0.9 0.3 -1.4 -1.5 -0.5 -0.2 1.1
Leg fat-free mass (left) 0.1 0.7 2.0 0.4 -0.3 -0.0 1.4 -1.3 0.4 0.8 0.5 1.3 0.4 -1.1 -0.1 -0.4 -1.4
Trunk fat percentage 0.3 1.1 5.4 -0.1 -0.0 0.4 1.6 -0.9 -0.1 0.6 1.7 2.3 -0.1 -1.4 1.1 0.2 0.4
Hand grip strength (right) 0.4 1.0 2.5 1.5 0.9 -1.2 0.4 -0.6 1.6 0.3 1.0 1.0 1.5 0.5 0.9 0.6 0.5
Townsend deprivation index at recruitment 0.3 0.4 0.9 0.7 0.6 -1.0 -0.2 -0.2 0.7 -0.1 0.4 -0.4 0.7 0.5 0.8 0.9 0.1
Current tobacco smoking 0.5 0.8 2.2 -1.1 -0.6 1.1 -1.1 -0.6 -1.2 -1.5 0.1 -0.6 -1.3 -0.5 0.3 -0.3 0.6
Average weekly fortified wine intake 0.2 0.3 0.8 -0.5 -0.9 0.2 -0.6 -0.6 -0.6 -0.5 -0.5 -0.3 -0.6 -0.3 -0.2 -0.3 -0.8
Maternal smoking around birth 1.0 1.5 6.5 0.6 0.9 -0.9 1.6 2.5 0.4 0.9 0.9 1.2 0.4 1.2 0.9 1.9 0.9
Fed-up feelings 0.6 1.1 2.4 1.2 1.5 -1.3 1.0 1.4 1.1 1.1 0.5 1.4 1.1 1.0 0.2 0.8 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 2.5 1.3 1.3 -1.6 -0.5 0.8 1.3 1.1 0.3 -0.2 1.3 1.2 1.4 0.3 0.1
Relative age voice broke 0.4 0.6 2.0 -0.8 -1.2 0.3 -0.7 -0.5 -0.9 -1.4 -0.6 -0.9 -1.0 -0.6 -0.4 -0.5 -0.1
Taking other prescription medications 0.2 0.3 0.8 0.6 0.8 -0.3 -0.6 0.3 0.4 0.3 0.9 0.6 0.3 0.2 0.6 0.7 0.7
Age when periods started (menarche) 0.1 0.2 1.0 0.2 0.5 -0.5 1.0 0.3 0.2 -0.0 0.3 0.6 0.3 -0.1 0.0 0.4 0.0
Bilateral oophorectomy (both ovaries removed) 0.2 0.3 1.0 -0.5 -0.9 0.8 -0.5 -0.2 -0.5 -0.2 -0.3 -1.0 -0.5 -0.1 0.0 -0.1 -0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.9 2.0 6.5 1.4 1.8 -1.1 2.5 0.5 1.5 0.9 1.9 0.8 1.5 1.1 1.5 0.8 0.9
Tinnitus: Yes, but not now, but have in the past 0.2 0.3 1.0 -0.7 -0.1 0.4 0.5 -0.3 -0.7 -0.1 0.0 -0.0 -0.8 -0.3 -0.6 -1.0 -0.2
Qualifications: CSEs or equivalent 1.2 1.5 4.1 0.7 1.4 -1.0 1.7 1.7 0.8 2.0 0.7 1.4 0.8 1.4 1.2 0.9 0.3
Serious illness, injury or assault to yourself 0.6 0.8 3.5 0.4 1.1 -0.4 1.0 1.3 0.6 1.9 -0.3 1.2 0.6 0.1 -0.6 0.5 -0.1
High blood pressure 0.4 1.0 2.8 -1.1 -0.8 0.8 0.1 -0.6 -1.2 0.1 -1.0 0.6 -1.2 -1.6 -1.1 -1.0 -1.7
Hayfever, allergic rhinitis or eczema 0.9 1.8 5.6 0.3 1.0 -2.4 -1.8 0.3 0.5 -2.1 -1.8 -1.4 0.4 2.3 -0.5 -0.2 0.7
Multivitamins +/- minerals 0.5 0.6 3.5 0.7 -0.0 -0.5 0.6 -0.8 0.7 0.4 -0.5 -1.0 0.7 -0.0 -1.0 -0.6 -1.9
Stomach or abdominal pain in last month 0.1 0.1 1.2 -0.1 -0.0 0.1 0.1 1.1 -0.2 0.2 0.1 -0.1 -0.2 0.4 0.2 0.6 -0.1
Supplements: Glucosamine 0.6 0.7 3.6 1.1 1.0 -0.8 1.9 -0.3 1.2 0.1 0.2 -0.5 1.2 0.6 -0.3 -0.0 -0.5
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.0 1.1 0.9 -1.2 0.9 0.6 1.2 0.9 0.0 0.2 1.2 1.4 0.1 0.6 -0.0
Medication: Atenolol 0.6 0.7 3.6 -0.7 -0.2 0.7 -0.6 -0.0 -0.9 0.3 -0.5 0.9 -0.8 -1.9 -0.9 -0.2 -1.3
Medication: Levothyroxine sodium 2.4 4.0 7.5 2.5 2.2 -1.5 2.1 0.6 2.4 2.5 2.6 2.7 2.4 0.7 1.6 1.8 0.7
Sitting height 0.2 1.4 7.3 -0.7 -1.0 0.7 0.1 -1.2 -0.7 0.2 -1.0 0.7 -0.7 -2.7 -1.3 -0.9 -2.0
Chronic bronchitis/emphysema (father) 0.3 0.4 0.8 0.6 0.6 -0.6 0.9 -0.3 0.7 0.6 0.1 -0.8 0.8 0.6 -0.1 -0.4 -0.5
High blood pressure (mother) 0.5 0.8 3.4 0.3 1.6 0.0 -0.3 -0.2 0.2 1.7 0.8 1.8 0.1 0.4 0.8 0.4 -0.3
Body mass index (BMI) 0.1 0.6 3.1 0.3 -0.0 0.1 1.2 -0.7 0.2 0.6 1.4 1.8 0.2 -0.6 0.8 -0.1 0.0
Impedance of leg (left) 0.3 1.3 3.7 -1.4 -0.3 1.5 -1.2 -0.4 -1.5 -1.3 -0.8 0.3 -1.5 -1.9 -0.8 -0.2 0.8
Leg predicted mass (left) 0.1 0.8 2.1 0.4 -0.3 -0.1 1.4 -1.4 0.4 0.8 0.6 1.4 0.4 -1.1 -0.1 -0.5 -1.4
Trunk fat mass 0.3 1.2 5.6 -0.3 -0.3 0.6 1.5 -1.2 -0.3 0.7 1.4 2.4 -0.3 -1.8 0.6 -0.1 -0.2
Waist circumference 0.2 0.9 3.7 0.3 0.3 0.2 1.8 -0.8 0.3 1.0 1.3 1.9 0.3 -1.0 0.6 -0.0 -0.3
Number of incorrect matches in round 0.3 0.5 1.3 -0.8 -1.2 0.9 -1.1 0.6 -0.9 -0.1 -0.5 0.2 -0.9 -0.7 -0.2 0.4 0.4
Past tobacco smoking 0.4 0.7 4.2 -0.7 -0.4 0.5 -0.0 -0.7 -0.7 -1.0 -0.8 -0.2 -0.7 -0.3 -1.2 -0.7 -2.1
Alcohol usually taken with meals 0.9 1.5 3.8 1.5 1.9 -1.1 -0.1 0.7 1.4 1.2 1.0 0.3 1.4 2.0 1.1 0.6 0.9
Nervous feelings 0.5 1.0 1.9 -1.1 -0.5 1.1 -1.4 -1.4 -1.1 -0.6 -1.0 -1.0 -1.1 -0.6 -0.6 -1.3 -0.9
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.7 1.6 1.0 1.3 -0.9 -0.0 1.1 0.8 -0.0 0.9 0.3 0.8 1.0 0.9 0.5 0.9
Hearing difficulty/problems with background noise 0.5 0.9 3.5 -0.4 -0.6 0.3 -0.3 -1.0 -0.3 -0.1 -1.4 -1.5 -0.2 -0.4 -0.8 -1.9 -1.4
Hair/balding pattern: Pattern 2 0.3 0.4 1.4 -0.7 0.0 0.8 0.4 -0.4 -0.8 -0.9 0.5 0.4 -0.8 -0.4 0.5 -0.0 1.2
Had menopause 1.1 1.4 2.7 -1.3 -1.2 1.3 -0.3 -0.6 -1.5 -1.0 -1.0 -0.6 -1.5 -1.4 -1.2 -1.1 -1.6
Had other major operations 2.0 2.5 6.6 1.5 1.6 -1.7 2.6 1.2 1.6 1.8 1.9 1.3 1.6 1.0 1.1 1.8 0.1
Forced vital capacity (FVC) 0.1 0.4 1.5 -0.7 -0.8 0.7 0.3 -0.9 -0.8 -0.2 -0.4 0.0 -0.7 -1.2 -0.2 -0.2 -0.4
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 4.1 0.5 0.7 -0.2 2.0 0.1 0.4 0.4 0.9 1.0 0.5 -0.1 0.4 0.3 0.2
Ever unenthusiastic/disinterested for a whole week 0.7 0.9 1.8 1.0 0.9 -1.0 0.6 0.8 0.9 0.6 1.2 0.7 0.9 1.3 1.1 1.0 0.6
Qualifications: None of the above 0.6 1.2 3.2 1.0 1.0 -0.7 0.6 1.7 1.0 0.4 1.4 0.8 1.0 0.8 1.1 1.3 1.8
Financial difficulties in last 2 years 0.1 0.2 0.6 0.3 0.6 -0.4 0.7 0.0 0.4 0.2 0.2 -0.6 0.3 0.6 -0.2 0.0 -0.1
Mouth/teeth dental problems 0.2 0.2 1.1 0.1 0.1 -0.4 0.1 0.2 -0.1 0.6 -0.1 0.2 -0.1 1.0 0.7 0.3 -0.9
Heart attack 0.5 0.7 1.4 0.9 1.1 -0.4 0.0 0.8 0.5 1.2 0.9 0.6 0.6 0.8 0.8 1.0 1.0
Allergy 0.6 1.3 4.8 0.0 -0.7 1.7 1.9 0.1 -0.0 2.2 1.2 1.0 0.1 -1.8 -0.2 0.2 -0.6
Pain all over the body in last month 0.9 0.9 2.3 1.4 1.2 -1.2 0.4 1.2 1.4 1.0 0.2 0.4 1.5 0.3 0.3 0.2 0.8
Diabetes (self-reported) 0.9 1.4 3.9 -1.1 -0.8 1.8 -1.2 -1.2 -1.0 -1.4 -0.9 -0.9 -0.9 -2.0 -1.0 -1.1 0.9
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 3.4 -0.3 0.7 -0.6 -1.9 0.6 -0.1 -0.9 -0.9 0.7 -0.1 0.2 -0.4 0.1 0.4
Medication: Ramipril 0.2 0.3 1.3 0.4 0.7 -0.3 0.5 0.0 0.1 1.2 0.7 0.8 0.1 0.2 0.7 0.3 -0.0
Medication: Simvastatin 0.7 1.0 2.8 -0.7 -1.1 0.8 -1.4 -0.6 -1.0 -0.3 -0.8 -0.6 -1.0 -1.7 -1.3 -1.1 -0.6
Fluid intelligence score 1.2 2.5 4.0 -1.6 -1.9 1.4 -1.5 -1.4 -1.8 -2.0 -1.4 -1.0 -1.8 -1.8 -1.7 -1.7 -0.5
Illnesses of siblings 2.1 3.0 10.4 -1.1 -1.8 0.7 -0.6 -1.9 -1.0 -1.7 -2.2 -3.2 -1.0 -0.9 -1.8 -1.8 -2.2
Neuroticism score 0.0 0.1 0.5 0.1 0.1 0.1 -0.5 -0.3 0.1 0.4 -0.1 0.3 0.0 -0.0 -0.3 -0.7 -0.5
Weight 0.3 1.5 6.4 -0.6 -0.9 1.0 0.9 -1.9 -0.6 0.3 0.5 2.0 -0.6 -2.5 -0.2 -0.8 -1.4
Impedance of arm (right) 0.0 0.2 0.9 -0.1 0.4 -0.3 0.9 -0.6 -0.0 -0.3 0.4 -0.4 0.0 0.2 0.6 0.4 0.6
Arm fat percentage (right) 0.2 0.6 2.5 -0.1 -0.2 0.3 1.6 -0.9 -0.2 0.4 1.3 1.4 -0.2 -0.7 0.7 -0.2 0.1
Trunk fat-free mass 0.4 2.3 7.2 -1.2 -1.5 1.4 -0.2 -1.7 -1.2 -0.2 -1.2 0.8 -1.2 -2.7 -1.8 -1.5 -2.5
Hip circumference 0.4 1.7 6.4 -0.8 -1.2 1.3 1.1 -1.9 -0.9 0.4 0.2 1.8 -0.8 -2.5 -0.5 -0.7 -1.7
Time employed in main current job 0.5 0.6 2.1 -0.9 -0.5 1.2 -1.0 -1.4 -0.6 -0.9 -0.3 0.1 -0.6 -1.0 -0.5 -0.6 -0.1
Alcohol intake versus 10 years previously 0.5 0.7 1.6 0.7 -0.7 -0.8 1.0 0.9 0.7 1.0 -0.0 -1.1 0.9 0.7 0.1 0.7 -1.3
Father’s age at death 3.1 4.2 12.7 -2.1 -1.6 2.4 -3.6 -1.1 -2.2 -1.4 -2.4 -1.8 -2.2 -1.6 -1.9 -2.0 -1.1
Worrier / anxious feelings 0.9 1.8 3.4 -1.2 -1.6 1.4 -1.6 -1.1 -1.2 -0.8 -1.6 -0.2 -1.2 -1.0 -1.3 -1.9 -1.6
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 1.0 -0.1 0.2 0.5 0.1 -0.6 -0.1 -0.1 0.1 0.5 -0.1 -1.0 0.1 -0.9 0.4
Falls in the last year 0.7 0.9 2.4 -0.3 -0.9 0.6 0.6 -1.4 -0.3 -1.5 -1.1 -1.5 -0.3 -0.2 -0.6 -1.5 -0.6
Hair/balding pattern: Pattern 3 0.3 0.5 1.0 -0.8 -0.6 0.9 -0.7 0.7 -0.7 -1.0 -0.9 -0.6 -0.8 0.2 -0.8 -0.2 -0.2
Number of live births 0.2 0.3 1.7 -0.3 -0.5 -0.0 0.5 -0.7 -0.3 0.1 -0.3 0.3 -0.3 -0.7 -0.6 -0.4 -1.3
Forced expiratory volume in 1-second (FEV1) 0.1 0.4 1.7 -0.4 -0.8 0.8 0.5 -1.3 -0.6 -0.5 0.1 0.3 -0.5 -1.3 -0.1 -0.2 -0.1
Pulse rate 0.2 0.3 1.3 -0.3 -0.1 -0.5 -0.7 -0.4 -0.3 -1.1 -0.7 -0.6 -0.3 -0.1 -0.7 -0.8 0.2
Happiness 0.6 0.7 2.2 0.7 0.7 -0.4 1.0 0.2 0.7 0.3 1.4 0.3 0.6 1.5 1.1 0.5 1.0
Noisy workplace 0.2 0.2 0.9 -0.2 0.1 0.2 0.3 0.7 -0.3 -0.1 0.2 -0.6 -0.3 0.7 0.5 0.4 1.0
Qualifications: A levels/AS levels or equivalent 2.6 5.8 9.3 -2.4 -2.8 2.3 -2.2 -3.0 -2.4 -2.9 -2.2 -2.1 -2.4 -2.4 -2.5 -2.2 -1.4
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 2.8 0.9 0.1 -1.7 0.7 0.9 1.1 0.7 0.6 -0.1 1.0 1.1 0.8 1.5 -0.5
Mouth/teeth dental problems: Dentures 1.5 2.5 6.1 -1.6 -1.3 1.7 -2.2 -0.3 -1.3 -2.5 -1.5 -2.0 -1.4 -1.2 -1.8 -1.6 0.1
Asthma 0.8 1.6 6.2 -0.9 -0.6 0.3 -2.5 -0.1 -1.1 -2.3 -1.6 -1.3 -1.2 0.3 -0.4 -1.6 0.3
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 0.9 0.2 -0.2 -0.1 -0.2 0.1 0.2 -0.9 -0.6 -0.9 0.2 -0.6 -0.3 -0.9 -0.3
Medication: Cholesterol lowering 0.8 1.2 3.9 -1.1 -0.7 1.1 -1.4 -0.1 -1.4 -0.6 -0.8 -0.1 -1.4 -1.5 -2.0 -0.4 -0.9
Depression (self-reported) 0.3 0.3 1.7 -0.3 -0.7 -0.1 -0.2 -0.4 -0.3 -0.5 -0.3 -0.0 -0.3 -0.9 -1.3 -0.4 -0.7
Medication: Lansoprazole 0.2 0.3 0.9 0.3 -0.0 -0.7 1.0 0.5 0.5 0.1 0.0 -0.5 0.5 0.8 0.4 0.4 0.5
Prospective memory result 1.5 1.9 3.2 -1.5 -1.5 1.2 -1.3 -1.7 -1.4 -0.9 -1.7 -1.2 -1.4 -1.1 -1.0 -1.8 -0.9
Lung cancer (father) 0.3 0.4 2.0 0.1 0.1 -0.3 0.6 -0.4 0.3 0.3 1.4 1.1 0.2 -0.3 0.5 0.8 0.6
Illnesses of mother 0.3 0.4 1.1 0.5 -1.1 -0.2 0.7 0.7 0.3 -0.7 -0.0 -1.0 0.4 0.1 0.2 -0.2 1.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.0 0.1 0.5 -0.3 -0.7 0.6 0.4 -0.4 -0.4 -0.0 -0.2 -0.1 -0.3 -0.5 0.1 0.2 0.0
Pulse wave Arterial Stiffness index 0.8 1.0 1.7 -1.1 -0.4 0.8 -1.2 -0.9 -1.2 -0.6 -1.0 0.3 -1.2 -1.1 -1.2 -0.5 -1.3
Impedance of arm (left) 0.1 0.3 1.0 -0.1 0.4 -0.1 0.7 -0.3 0.0 -0.2 0.6 -0.1 0.0 0.2 1.0 0.6 1.0
Arm fat mass (right) 0.2 0.7 3.7 -0.2 -0.4 0.6 1.2 -1.1 -0.3 0.5 1.0 1.9 -0.3 -1.3 0.4 -0.2 -0.4
Trunk predicted mass 0.4 2.2 6.7 -1.2 -1.5 1.4 -0.2 -1.6 -1.2 -0.2 -1.2 0.7 -1.2 -2.6 -1.8 -1.4 -2.4
Standing height 0.4 3.8 17.5 -1.6 -1.5 1.8 -0.1 -2.4 -1.6 -0.3 -1.5 1.2 -1.6 -4.2 -2.0 -1.2 -2.8
Length of working week for main job 0.3 0.3 0.8 -0.5 -0.6 0.6 0.3 -0.9 -0.6 -0.3 0.1 0.7 -0.6 -0.6 -0.2 -0.6 -0.5
Exposure to tobacco smoke at home 0.5 0.5 1.2 0.5 0.7 -0.7 0.5 0.7 0.4 -0.0 0.9 -0.7 0.4 1.1 0.9 0.8 0.9
Breastfed as a baby 0.4 0.6 1.6 -0.7 -1.2 1.0 0.3 -1.1 -0.6 -1.2 -0.2 -0.7 -0.7 -0.3 -0.3 -0.8 0.2
Tense / ‘highly strung’ 1.5 2.6 5.1 -1.3 -1.7 1.3 -1.9 -0.9 -1.3 -1.1 -2.0 -1.7 -1.3 -1.0 -2.3 -2.0 -1.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.2 0.3 0.6 -0.3 -0.8 0.1 -0.7 -0.8 -0.4 -0.3 -0.5 -0.6 -0.3 -0.6 -0.6 -0.7 -0.5
Hair/balding pattern: Pattern 4 0.4 0.9 3.0 1.1 0.6 -1.3 1.0 0.6 1.0 1.7 0.1 0.1 1.0 0.6 0.1 0.7 -1.4
Birth weight of first child 0.4 0.8 3.1 0.6 0.6 -1.2 -0.5 1.7 0.6 0.4 -0.3 -0.6 0.6 1.8 0.5 0.7 1.0
Peak expiratory flow (PEF) 0.1 0.1 0.5 -0.1 -0.3 0.2 0.3 -0.6 -0.2 0.0 -0.2 0.2 -0.2 -0.7 -0.5 0.2 -0.7
Pulse wave reflection index 0.5 0.7 1.8 -1.1 -0.9 1.4 -0.6 -0.5 -1.0 -0.1 -1.0 -0.4 -1.1 -0.6 -0.7 -0.3 -0.7
Ever highly irritable/argumentative for 2 days 2.4 2.8 7.5 1.2 1.0 -1.0 1.4 2.6 1.3 0.7 1.8 0.4 1.3 2.7 2.1 1.8 2.3
Loud music exposure frequency 0.3 0.3 0.7 0.5 0.3 -0.3 0.8 0.3 0.3 0.4 0.5 0.1 0.3 0.8 0.8 0.7 0.7
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 1.1 -0.9 -0.7 1.0 -0.7 -0.1 -1.0 -0.2 -0.3 0.9 -1.1 -0.8 -0.7 0.4 -0.1
Mouth/teeth dental problems: Bleeding gums 0.8 1.0 2.4 1.2 0.7 -1.1 0.7 0.2 1.2 1.2 1.3 1.5 1.2 0.1 0.9 1.0 0.3
Blood clot in the leg (DVT) 0.7 0.9 2.9 1.0 0.4 -0.6 1.5 -0.1 0.6 0.9 1.7 0.9 0.6 0.5 1.1 1.3 0.7
Medication: Paracetamol 0.9 1.5 4.3 -1.0 -1.1 0.5 -1.0 -0.2 -1.0 -1.4 -1.7 -1.3 -1.0 -1.2 -2.1 -1.2 -1.4
Headache pain in last month 0.1 0.1 0.4 -0.2 -0.4 0.5 -0.1 0.7 -0.1 0.5 -0.2 0.4 -0.1 0.1 -0.0 0.1 -0.5
Medication for cholesterol, blood pressure or diabetes 1.4 2.2 4.8 1.6 1.4 -1.5 1.4 0.6 2.0 0.9 1.6 0.3 1.9 1.9 2.2 1.3 1.0
Glaucoma (self-reported) 2.0 2.4 5.4 1.8 1.6 -1.6 1.8 0.2 1.8 0.4 1.9 1.3 1.9 1.3 2.3 0.6 1.4
Gout (self-reported) 2.5 3.4 7.3 1.5 2.5 -1.2 0.9 1.5 1.4 1.7 2.3 2.7 1.4 0.8 2.2 2.2 2.3
Hypothyroidism/myxoedema (self-reported) 1.9 3.8 7.0 2.5 2.1 -1.3 2.6 -0.0 2.5 1.9 2.6 2.2 2.5 0.2 1.8 1.1 1.0
Medication: Amlodipine 0.4 0.5 1.4 -0.2 -0.6 0.3 0.3 0.8 -0.4 1.0 -1.0 1.2 -0.4 -0.7 -0.9 -0.4 -1.0
Medication: Ventolin 100micrograms inhaler 0.3 0.4 0.9 -0.4 -0.0 0.1 -0.8 1.0 -0.8 -0.8 -0.2 0.4 -0.9 0.8 0.4 0.1 0.5
Birth weight 0.4 0.8 2.3 1.0 0.4 -1.1 0.3 1.1 0.9 0.7 0.7 -0.1 1.0 1.5 1.2 1.0 0.9
Chronic bronchitis/emphysema (mother) 0.9 1.1 2.4 0.9 1.2 -1.0 1.6 0.4 0.9 -0.9 1.3 -0.1 0.9 1.0 1.1 1.1 1.4
High blood pressure (siblings) 1.3 1.9 6.5 0.8 1.4 -0.7 0.7 1.3 0.8 1.1 2.0 2.5 0.7 1.2 1.2 1.6 1.8
Forced vital capacity (FVC), Best measure 0.1 0.2 0.6 -0.4 -0.8 0.5 0.5 -0.2 -0.5 -0.2 -0.7 -0.5 -0.4 -0.6 -0.5 -0.0 -0.3
Body fat percentage 0.2 0.8 4.6 -0.3 -0.2 0.7 1.1 -0.8 -0.4 0.5 1.4 2.1 -0.4 -1.3 0.8 0.0 0.4
Leg fat percentage (right) 0.2 0.7 4.5 -0.7 -0.5 1.0 0.1 -0.4 -0.8 0.2 0.6 2.1 -0.8 -1.5 0.0 -0.2 0.2
Arm fat-free mass (right) 0.3 1.4 6.2 -0.6 -1.0 1.0 0.1 -1.3 -0.7 0.3 -0.3 1.6 -0.7 -2.5 -1.0 -0.9 -1.9
Exposure to tobacco smoke outside home 0.1 0.1 0.3 0.4 0.3 -0.3 0.5 0.0 0.4 0.4 -0.1 -0.0 0.4 0.5 -0.2 -0.3 -0.2
Comparative body size at age 10 0.1 0.2 0.8 -0.2 -0.6 0.4 -0.3 -0.2 -0.2 -0.4 -0.4 -0.3 -0.2 -0.4 -0.2 -0.9 0.3
Number of full brothers 1.7 2.1 10.3 1.1 1.3 -0.9 3.2 1.7 1.0 0.8 1.6 1.2 1.0 0.9 1.1 1.9 1.0
Worry too long after embarrassment 0.2 0.4 1.8 0.5 0.1 -0.3 1.4 -0.2 0.4 0.5 0.9 0.1 0.5 0.4 1.0 -0.2 1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 2.1 -0.4 -0.3 0.3 -0.5 1.4 -0.2 0.0 -0.2 -0.0 -0.2 -0.3 -0.8 0.5 -0.2
Wheeze or whistling in the chest in last year 0.1 0.2 1.9 0.0 -0.3 -0.5 -0.3 1.4 -0.1 0.6 -0.1 0.7 -0.1 0.4 -0.1 0.1 0.0
Number of children fathered 0.7 0.8 2.6 0.4 0.3 0.2 -0.5 0.3 0.4 1.2 1.3 1.6 0.4 0.2 1.6 0.9 1.1
Reason for reducing amount of alcohol drunk: Health precaution 1.3 1.5 4.8 1.4 2.2 -1.4 1.1 0.1 1.5 1.4 0.3 -0.3 1.6 1.5 0.0 0.9 -0.8
Age at first live birth 0.6 1.0 2.4 1.2 0.9 -1.5 -1.1 -0.2 1.3 -0.0 0.5 0.1 1.3 1.5 1.0 0.1 0.9
Pulse wave peak to peak time 0.8 0.9 1.9 1.1 0.4 -0.8 1.4 0.8 1.2 0.7 1.1 -0.1 1.2 0.9 1.2 0.5 1.1
Health satisfaction 1.5 2.0 4.9 0.8 2.1 -1.3 1.0 2.0 0.9 0.6 1.4 1.4 0.9 2.2 1.6 1.5 0.7
Shortness of breath walking on level ground 0.3 0.3 2.5 -0.4 0.5 0.5 -0.6 0.7 -0.4 0.5 0.4 1.6 -0.4 0.0 0.2 0.2 -0.3
Qualifications: College or University degree 0.2 0.8 4.9 -0.2 -0.8 -0.2 0.2 -2.2 0.0 -0.9 -0.5 -0.6 -0.0 -0.7 -0.8 -0.6 -1.5
Eye problems/disorders: None of the above 0.8 0.9 2.2 -0.8 -1.4 0.9 -0.5 -0.2 -0.8 -0.4 -1.5 -0.8 -0.8 -0.9 -1.1 -0.9 -1.1
Mouth/teeth dental problems: Loose teeth 0.7 0.9 1.8 1.0 0.8 -0.7 0.9 0.7 0.9 0.5 1.2 0.1 1.0 1.1 1.2 1.1 1.4
Emphysema/chronic bronchitis 1.2 1.3 2.7 1.3 1.5 -0.7 0.6 0.7 1.3 0.1 1.5 0.8 1.2 0.9 1.2 1.4 1.6
Medication for pain relief, constipation, heartburn 0.8 1.4 3.9 1.0 0.7 -0.6 1.5 -0.4 1.2 1.3 1.5 0.6 1.2 1.8 2.0 0.8 1.1
Neck or shoulder pain in last month 0.9 1.3 4.6 0.9 1.1 -1.3 1.2 2.1 0.8 1.7 0.5 0.8 0.8 1.5 0.6 0.9 0.1
Medication: Blood pressure 0.5 0.9 1.9 -0.9 -0.9 0.9 -0.5 -0.2 -1.3 -0.3 -1.3 -0.1 -1.3 -1.3 -1.4 -1.0 -0.8
Angina (self-reported) 0.3 0.4 1.3 0.3 1.1 -0.4 -0.4 1.1 0.1 0.8 0.4 0.5 0.2 0.5 0.3 1.1 0.1
Migraine (self-reported) 1.0 1.3 3.5 0.9 1.3 -0.8 1.9 0.9 1.0 1.6 1.4 0.4 1.0 0.5 1.2 1.1 1.0
Medication: Ibuprofen 0.5 0.6 2.4 -0.3 -0.6 0.1 -0.5 -0.0 -0.2 -1.0 -1.3 -1.5 -0.2 -0.6 -0.8 -1.2 -0.9
Medication: Allopurinol 2.0 2.6 5.9 1.4 2.2 -1.0 1.4 1.2 1.4 1.7 2.0 2.4 1.4 0.5 1.5 1.5 1.9
Medication: Omeprazole 0.9 1.1 2.9 1.1 1.1 -1.4 0.5 1.7 0.8 1.1 1.1 1.5 0.8 0.7 0.0 1.3 -0.1
Medication: Seretide 50 evohaler 1.8 2.1 4.0 1.3 1.9 -1.2 1.3 1.0 1.4 0.3 1.8 0.9 1.4 2.0 1.9 1.3 1.6
Mean time to correctly identify matches 0.4 0.8 3.6 0.6 0.5 -0.6 0.6 1.8 0.3 1.0 0.4 0.9 0.3 1.2 0.0 1.9 -0.1
Heart disease (mother) 0.8 0.9 3.3 -1.1 -0.6 0.7 -1.8 0.1 -1.0 0.1 -1.0 -0.1 -1.0 -0.7 -0.9 -0.0 -1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.4 0.9 0.8 0.9 -0.7 0.7 -0.9 0.6 0.4 0.8 0.2 0.6 0.4 0.4 0.3 -0.3
Whole body fat mass 0.2 0.9 4.8 -0.4 -0.4 0.9 1.0 -0.9 -0.5 0.6 1.1 2.2 -0.5 -1.6 0.5 -0.1 -0.0
Leg fat mass (right) 0.2 0.8 5.4 -0.3 -0.3 0.8 0.8 -0.5 -0.3 0.8 0.9 2.3 -0.3 -1.4 0.4 0.0 0.2
Arm predicted mass (right) 0.3 1.3 5.6 -0.6 -0.9 1.0 -0.0 -1.0 -0.7 0.4 -0.4 1.6 -0.7 -2.4 -1.1 -0.8 -1.9
Pulse rate, automated reading 0.4 1.3 5.0 -0.9 -0.1 1.0 -1.6 -0.5 -1.1 -2.2 -0.6 -1.2 -1.1 -0.2 -0.8 -1.5 1.5
Alcohol intake frequency. 1.1 2.6 9.7 -1.1 -3.1 1.3 -0.1 -1.2 -1.2 -0.6 -1.5 -2.0 -1.1 -1.3 -1.6 -1.5 -2.4
Comparative height size at age 10 0.2 0.9 3.5 -0.7 -1.2 1.0 0.4 -1.7 -0.7 -0.5 -0.1 1.1 -0.6 -1.9 -0.3 0.3 -0.4
Number of full sisters 0.8 1.0 3.5 0.5 0.6 -0.2 0.1 0.3 0.4 0.9 1.7 1.2 0.3 0.9 1.9 1.2 1.6
Suffer from ‘nerves’ 0.6 1.0 2.7 -1.0 -0.7 1.2 -1.3 -0.8 -0.8 -0.2 -1.7 -0.7 -0.7 -0.6 -1.0 -1.4 -1.1
Overall health rating 0.5 1.1 4.3 0.3 0.8 -0.3 0.9 1.6 0.3 1.9 0.8 2.1 0.3 0.1 0.4 1.2 -0.9
Chest pain or discomfort 0.9 1.3 4.2 1.2 1.8 -1.2 0.5 1.4 1.0 0.8 0.9 0.5 1.0 2.0 1.0 0.6 0.6
Had major operations 0.7 0.8 2.5 -0.3 -0.5 0.1 -0.2 -1.6 -0.4 -0.7 -0.8 -0.9 -0.4 -1.4 -1.2 -1.2 -0.7
Age at last live birth 0.3 0.5 1.7 0.2 0.0 -0.7 -0.8 -1.1 0.4 -1.3 -0.3 -0.8 0.4 0.7 -0.2 -0.7 -0.8
Family relationship satisfaction 0.8 1.0 3.1 0.8 0.7 -0.4 1.1 1.1 0.8 1.8 1.1 0.3 0.8 1.6 1.0 0.7 1.1
Leg pain on walking 0.9 1.1 2.1 -1.0 -1.2 1.1 -0.4 -1.0 -1.1 -1.4 -0.9 -1.5 -1.1 -0.8 -0.9 -1.2 -1.1
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 4.0 -0.5 0.2 -0.3 0.1 2.0 -0.6 0.8 -0.6 0.2 -0.6 0.5 0.1 0.6 -0.4
Commuting to job workplace: Car/motor vehicle 0.4 0.4 1.8 0.0 0.4 0.2 -0.1 0.2 0.2 1.4 0.8 1.0 0.3 0.6 0.8 0.8 0.6
Illness, injury, bereavement, stress in last 2 years 0.6 0.8 3.9 -0.4 -0.4 0.1 -0.3 -2.0 -0.4 -1.6 -0.1 -0.7 -0.4 -0.7 -0.2 -1.2 -0.8
Medication: Aspirin 0.2 0.3 0.6 -0.2 0.2 -0.0 -0.8 -0.1 -0.4 -0.4 -0.8 -0.5 -0.4 -0.6 -0.8 -0.6 -0.6
Supplements: Vitamin C 4.4 5.2 12.4 -2.4 -2.5 2.4 -3.5 -1.2 -2.5 -2.2 -2.8 -2.2 -2.5 -1.4 -2.1 -2.2 -0.8
Knee pain experienced in last month 0.6 0.9 5.3 -0.9 -1.0 1.0 -0.2 -0.2 -0.9 0.2 -1.0 -0.8 -0.9 -0.7 -1.0 -0.7 -2.3
Hypertension (Self-reported) 0.6 1.6 3.1 -1.4 -1.1 1.1 -0.7 -0.7 -1.6 -0.1 -1.4 0.1 -1.5 -1.6 -1.4 -1.4 -1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.4 0.3 0.1 -0.2 0.6 0.6 0.3 0.3 1.0 1.2 0.3 0.3 0.7 0.8 0.6
Illnesses of father: Heart disease 0.6 0.8 3.2 -0.8 -0.8 0.1 -1.8 -0.0 -1.2 -1.0 -0.6 -1.6 -1.1 -0.0 0.2 -0.7 -0.1
Illnesses of siblings: Diabetes 1.0 1.2 4.1 0.2 0.5 -0.1 -0.3 2.0 0.0 1.0 0.8 1.7 0.0 1.1 1.7 1.3 1.1
Smoking status: Previous 0.2 0.3 1.4 0.4 0.2 -0.5 -0.1 0.7 0.3 1.2 0.3 -0.0 0.4 0.3 0.7 0.3 0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.9 2.3 -1.0 -1.2 0.7 -0.1 -1.2 -1.1 -0.5 -0.8 -0.4 -1.0 -1.5 -0.6 -0.8 -1.1
Whole body fat-free mass 0.2 1.4 4.9 -0.6 -1.1 0.9 0.4 -1.7 -0.6 0.1 -0.5 1.0 -0.6 -2.2 -1.2 -1.1 -2.2
Leg fat-free mass (right) 0.2 0.8 2.8 0.3 -0.4 0.1 1.4 -1.6 0.3 0.7 0.6 1.1 0.3 -1.2 -0.2 -0.5 -1.7
Arm fat percentage (left) 0.2 0.7 2.8 -0.2 -0.3 0.4 1.4 -0.8 -0.2 0.6 1.4 1.7 -0.2 -0.8 1.0 -0.1 0.2
Average weekly red wine intake 0.3 0.5 2.8 0.4 1.7 -0.8 -0.4 0.9 0.4 0.6 -0.3 1.1 0.3 0.5 0.2 0.2 0.4
Handedness (chirality/laterality): Left-handed 2.9 3.4 7.7 2.0 2.3 -1.2 2.1 -0.6 1.9 1.0 2.8 1.6 1.9 1.1 2.4 1.6 2.3
Mood swings 0.4 0.7 1.5 1.1 0.6 -1.0 -0.0 0.7 1.1 1.2 0.5 0.8 1.1 1.2 0.5 0.6 -0.0
Loneliness, isolation 0.5 0.8 2.1 -0.7 0.0 0.5 -0.9 -0.2 -0.8 -0.8 -0.8 -1.5 -0.9 0.2 -1.3 -0.8 -1.3
Long-standing illness, disability or infirmity 0.5 0.8 2.5 0.5 0.1 -0.6 0.2 1.6 0.4 1.5 -0.1 1.3 0.4 0.3 -0.9 0.4 -1.6
Ever had bowel cancer screening 2.1 2.5 5.0 -1.4 -2.0 1.3 -1.0 -1.2 -1.7 -0.4 -2.1 -0.7 -1.7 -1.3 -2.2 -1.6 -2.2
Diabetes diagnosed by doctor 0.4 0.6 4.5 -0.3 0.0 1.1 -0.8 -0.5 -0.2 -0.8 0.2 -0.3 -0.2 -0.9 0.5 -0.2 2.1
Ever had stillbirth, spontaneous miscarriage or termination 0.4 0.4 3.5 -0.3 -0.3 -0.4 -0.4 0.0 -0.2 1.2 -0.2 -0.5 -0.2 0.0 0.0 -0.2 -1.9
Friendships satisfaction 0.2 0.2 1.0 0.2 0.3 -0.4 0.3 0.7 0.2 1.0 0.4 -0.5 0.2 0.7 -0.4 0.3 0.4
Qualifications: nursing, teaching 0.3 0.5 1.2 -0.8 -0.8 0.9 -0.3 -1.0 -0.8 -1.1 0.1 -0.0 -0.9 0.4 0.3 0.1 0.9
Commuting to job workplace: Walk 0.3 0.3 1.1 -0.2 -0.2 -0.3 -0.5 -0.1 -0.2 -0.5 -0.8 -0.2 -0.2 -0.5 -1.0 -0.6 -0.9
Eye problems/disorders: Cataract 2.2 2.6 7.8 1.9 2.8 -1.8 1.2 0.8 1.7 0.9 2.0 0.5 1.7 1.9 0.7 1.8 1.2
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 3.2 0.4 -0.1 0.1 1.4 -1.8 0.4 0.0 0.2 -0.5 0.4 -1.1 -0.7 -1.1 -0.8
Medication for cholesterol 0.1 0.2 0.7 -0.4 -0.4 0.4 0.6 -0.1 -0.5 -0.8 0.2 -0.1 -0.4 -0.0 0.4 0.8 0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 1.0 -0.2 -0.1 0.6 -0.9 0.4 -0.3 -0.1 0.2 1.0 -0.4 -0.2 0.1 0.3 0.7
Back pain experienced in last month 0.1 0.2 0.6 -0.2 -0.1 0.4 0.1 0.5 -0.3 0.2 0.5 0.5 -0.3 0.5 0.4 0.7 0.4
Mineral and other dietary supplements 0.6 0.8 2.3 0.9 0.9 -0.7 0.7 0.1 0.8 0.1 1.4 0.1 0.8 0.6 1.5 0.3 1.4
Breast cancer (self-reported) 0.4 0.5 1.1 -1.0 -0.2 1.0 0.4 0.3 -1.0 0.6 0.2 0.8 -1.0 -0.6 -0.3 0.7 -1.1
Asthma (self-reported) 0.7 1.5 5.2 -0.9 -0.6 0.4 -2.2 0.1 -1.1 -2.3 -1.5 -1.2 -1.2 0.2 -0.5 -1.6 0.4
Osteoporosis (self-reported) 0.4 0.5 1.7 -0.3 -0.8 -0.1 -0.9 -0.2 -0.2 1.0 -0.9 0.2 -0.2 -0.8 -0.7 -0.1 -1.3
Osteoarthritis (self-reported) 0.6 0.8 2.1 0.8 0.7 -0.9 0.3 0.9 0.7 1.1 1.2 1.2 0.6 0.6 0.5 1.5 0.6
Medication: Aspirin 0.1 0.2 0.8 0.2 0.5 -0.2 -0.9 -0.0 -0.0 0.1 -0.5 -0.3 -0.0 -0.4 -0.3 -0.4 -0.5
Medication: Gliclazide 0.4 0.5 2.5 -0.3 -0.0 0.8 -0.2 -0.2 -0.6 -0.0 0.4 1.4 -0.6 -1.6 -0.3 0.1 0.7
Illnesses of father: None of the above (group 1) 0.3 0.3 1.5 0.3 -0.4 -0.1 0.4 -0.7 0.6 -0.9 0.7 0.4 0.5 0.3 0.4 0.2 1.2
Smoking status: Current 0.6 1.0 2.6 -1.2 -0.7 1.2 -1.4 -0.7 -1.2 -1.6 -0.1 -0.8 -1.3 -0.7 0.2 -0.4 0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 0.9 -0.3 -0.7 0.1 -1.0 0.4 -0.5 -0.8 -0.6 -0.2 -0.5 0.0 -0.7 0.1 0.4
Whole body water mass 0.2 1.4 5.2 -0.6 -1.1 0.8 0.5 -1.7 -0.6 0.2 -0.5 1.0 -0.6 -2.1 -1.1 -1.1 -2.3
Leg predicted mass (right) 0.2 0.8 2.6 0.4 -0.3 -0.0 1.5 -1.5 0.4 0.8 0.7 1.2 0.4 -1.2 -0.1 -0.4 -1.6
Arm fat mass (left) 0.2 0.8 4.7 -0.1 -0.3 0.5 1.3 -0.8 -0.2 0.8 1.2 2.2 -0.2 -1.3 0.6 0.0 -0.2
Number of self-reported non-cancer illnesses 0.2 0.4 1.2 -0.2 0.1 0.2 -0.7 -0.5 -0.4 -0.3 -0.4 0.6 -0.5 -1.0 -1.1 -0.8 -0.8
Average weekly champagne plus white wine intake 0.9 1.3 2.7 1.2 1.6 -1.0 1.2 0.4 1.3 0.6 1.4 1.1 1.2 0.5 0.9 1.3 1.4
Miserableness 0.2 0.3 1.6 0.1 -0.1 -0.4 -0.2 1.3 -0.1 0.9 0.0 1.1 -0.1 0.5 0.6 0.4 -0.3
Guilty feelings 0.2 0.2 1.0 0.1 -0.4 0.0 -0.0 0.9 0.0 1.0 0.1 0.9 0.0 -0.0 -0.1 0.3 -0.8
Wears glasses or contact lenses 3.8 4.4 13.5 -2.1 -2.3 1.2 -1.8 -1.2 -2.0 -0.8 -2.7 -1.4 -2.0 -1.3 -3.1 -1.8 -3.7
Ever taken oral contraceptive pill 0.8 0.8 3.4 0.6 0.5 -0.9 1.8 0.4 0.9 0.5 1.4 0.7 1.0 -0.2 0.8 1.3 0.6
Hearing aid user 0.8 0.9 2.7 -0.9 -0.7 0.4 -1.6 -0.8 -0.8 -0.7 -1.3 -1.2 -0.8 -0.4 -1.2 -1.1 -0.8
Mother’s age at death 0.1 0.2 0.9 -0.1 -0.3 0.8 -1.0 -0.2 -0.1 -0.1 -0.5 -0.1 -0.1 -0.1 -0.6 0.2 0.4
Financial situation satisfaction 6.9 8.6 14.4 2.4 3.2 -2.8 3.7 3.0 2.5 2.9 3.2 1.9 2.5 3.7 3.0 3.8 1.5
Tinnitus: Yes, now most or all of the time 0.5 0.6 3.2 -0.6 -0.8 0.7 -0.7 0.7 -0.7 0.7 -0.6 1.8 -0.7 -0.6 -0.1 0.2 -0.6
Commuting to job workplace: Public transport 0.4 0.5 1.2 1.1 0.8 -0.8 1.0 0.2 1.1 -0.0 0.2 -0.5 1.0 0.9 0.0 0.4 -0.1
Eye problems/disorders: Glaucoma 0.5 0.6 1.3 1.0 1.0 -1.1 1.2 -0.1 1.0 0.5 0.7 0.3 1.0 0.6 0.7 0.6 -0.1
Medication: Blood pressure 0.6 1.1 3.1 -1.0 -0.3 0.9 -0.6 -0.4 -1.1 0.0 -0.9 1.2 -1.1 -1.6 -1.1 -1.1 -1.8
Pain type(s) experienced in last month: Hip pain 0.9 1.2 3.4 0.8 0.6 -1.2 1.2 1.8 0.6 1.6 0.7 0.6 0.5 1.3 0.4 1.9 0.2
Supplements: Fish oil (including cod liver oil) 0.2 0.3 1.1 -0.5 -0.3 0.2 -0.7 1.1 -0.5 0.2 -0.5 0.8 -0.5 -0.1 -0.3 0.7 -0.2
High cholesterol (Self-reported) 1.0 1.8 3.6 -1.3 -1.3 1.3 -1.9 -0.9 -1.6 -0.7 -1.0 -1.2 -1.6 -1.3 -1.9 -1.4 -0.7
Medication: Bendroflumethiazide 0.5 0.7 3.2 -0.8 0.3 0.9 -0.1 -0.5 -1.0 -0.0 -0.6 0.4 -0.9 -1.8 -0.8 -1.1 -1.0
Medication: Paracetamol 0.5 0.7 2.0 -0.6 -0.7 0.2 -1.1 0.3 -0.6 -1.0 -1.4 -1.0 -0.5 -0.7 -1.4 -0.7 -0.8
Medication: Lisinopril 1.0 1.2 3.2 -0.7 -1.0 1.1 -1.1 -1.0 -0.7 -1.0 -1.7 -1.4 -0.7 -0.9 -1.2 -1.8 -0.7
Medication: Atorvastatin 0.4 0.5 1.3 0.2 0.9 -0.5 -1.2 0.8 0.3 0.9 -0.3 0.3 0.3 1.0 -0.5 0.6 -1.0
Illnesses of father: High blood pressure 0.5 0.6 2.6 -0.9 -0.4 0.7 -0.5 -0.4 -1.1 0.5 -0.8 0.2 -1.0 -0.9 -0.4 -0.4 -1.6
Alcohol drinker status: Never 0.3 0.4 2.5 0.3 0.1 0.1 1.6 -0.3 0.3 0.7 0.7 1.1 0.4 -0.5 0.3 0.2 -0.1
Ever smoked 0.3 0.5 4.1 0.6 0.0 -0.1 0.4 0.4 0.5 0.4 0.6 -0.3 0.5 0.2 0.9 0.5 2.0
Basal metabolic rate 0.3 1.4 5.2 -0.6 -1.1 0.9 0.6 -1.8 -0.6 0.3 -0.2 1.4 -0.6 -2.3 -1.0 -1.0 -2.0
Leg fat percentage (left) 0.2 0.8 4.0 -0.7 -0.6 1.2 0.1 -0.7 -0.8 0.1 0.7 2.0 -0.8 -1.7 -0.1 -0.2 0.1
Arm fat-free mass (left) 0.3 1.4 5.6 -0.6 -0.9 0.8 0.4 -1.4 -0.6 0.3 -0.2 1.7 -0.6 -2.4 -1.1 -0.9 -1.8
Number of operations (self-reported) 0.7 1.1 3.3 1.1 0.9 -1.1 1.8 0.2 0.9 1.5 1.4 0.8 0.9 -0.2 0.7 1.2 0.0
Average weekly beer plus cider intake 3.2 4.6 9.3 2.6 3.0 -2.3 2.4 2.4 2.6 2.0 1.1 -0.2 2.7 2.5 1.4 1.9 1.3
Irritability 0.5 0.9 2.4 1.0 0.4 -1.2 -0.1 1.2 0.9 1.3 0.4 1.2 0.9 1.5 0.5 0.8 -0.1
Risk taking 0.6 0.9 2.3 1.5 0.4 -1.0 0.8 0.7 1.3 1.3 0.8 0.3 1.3 0.8 0.9 0.8 0.2
Ever had prostate specific antigen (PSA) test 0.7 0.8 1.8 1.3 0.8 -1.1 1.3 0.8 1.3 0.4 0.4 0.2 1.3 0.9 0.3 0.6 0.9
Fractured/broken bones in last 5 years 0.2 0.2 1.6 0.1 0.3 0.2 -0.9 0.0 -0.1 -0.4 -0.4 -0.2 -0.1 -0.1 0.6 0.1 1.2
Age started oral contraceptive pill 3.3 4.1 7.0 -2.5 -2.4 2.6 -2.0 -0.9 -2.4 -1.9 -1.8 -0.7 -2.4 -1.9 -2.4 -1.3 -1.9
Diastolic blood pressure, automated reading 0.2 0.8 2.1 -1.1 -0.4 0.8 0.3 -0.8 -1.0 -0.2 -0.8 0.7 -1.0 -0.9 -0.9 -1.0 -1.4
Ever depressed for a whole week 0.1 0.1 0.4 -0.3 -0.6 -0.1 0.3 -0.0 -0.4 -0.5 0.3 -0.3 -0.4 0.6 0.1 0.3 -0.5
Unable to work because of sickness or disability 0.5 0.6 2.3 0.3 0.2 -0.8 0.8 0.6 0.3 -0.9 -0.4 -1.3 0.3 -0.1 -1.5 -0.2 -1.2
Commuting to job workplace: Cycle 0.7 0.8 3.1 0.6 -0.3 -0.5 1.2 -0.6 0.8 -1.3 0.9 -0.9 0.7 0.8 0.6 -0.1 1.8
Myopia 0.1 0.2 1.4 0.2 0.3 -0.4 0.3 1.2 0.2 0.4 -0.2 -0.4 0.2 0.5 -0.0 0.2 0.2
Vascular/heart problems diagnosed by doctor 0.3 0.9 4.5 0.7 0.4 -0.3 -0.3 0.0 0.9 -0.7 1.1 -0.8 0.9 1.4 1.2 0.6 2.1
Cholesterol lowering medication 0.8 1.2 3.8 -0.8 -0.5 0.8 -1.9 -0.5 -0.9 0.4 -1.4 -0.5 -0.9 -0.9 -1.3 -1.6 -1.7
Medication: Omeprazole (e.g. Zanprol) 0.7 0.8 3.6 0.6 0.8 -1.1 0.1 1.9 0.4 0.7 0.6 1.3 0.3 0.9 0.1 1.3 0.1
Pain experienced in last month 0.2 0.4 1.1 0.3 0.6 -0.6 -0.6 -1.0 0.4 -1.0 -0.2 -0.9 0.4 -0.1 -0.2 -0.7 -0.2
Supplements: Calcium 0.6 0.6 1.7 0.9 0.4 -1.1 1.1 0.5 0.9 1.3 0.1 0.0 0.9 0.7 -0.6 1.0 -0.3
Basal cell carcinoma (self-reported) 0.6 0.7 2.3 0.7 0.5 -0.1 1.2 -1.4 0.6 -1.5 0.3 -1.1 0.6 -0.6 -0.6 -1.1 0.1
Heart attack/myocardial infarction (self-reported) 0.6 0.7 1.5 0.9 0.9 -0.4 -0.1 0.9 0.5 1.2 1.0 0.8 0.5 0.7 0.9 1.1 1.1
Deep venous thrombosis (DVT) (self-reported) 0.9 1.2 3.6 1.1 0.4 -0.7 1.6 -0.1 0.8 1.1 1.9 1.1 0.8 0.7 1.5 1.4 0.6
Heart disease (siblings) 3.4 4.2 7.4 2.1 1.9 -1.8 1.2 2.2 2.2 1.8 2.7 2.4 2.2 1.4 2.2 2.2 2.1
Alcohol drinker status: Previous 1.3 1.5 3.3 -1.4 -1.1 1.8 -1.0 -1.4 -1.4 -0.6 -0.4 -0.8 -1.4 -1.6 -1.1 -0.5 -1.5
Pack years of smoking 0.5 0.7 2.8 0.6 0.5 -1.0 0.6 1.7 0.7 0.8 0.5 0.5 0.7 1.2 0.5 1.2 -0.4
Impedance of whole body 0.1 0.3 1.7 -0.5 0.4 0.4 0.1 0.0 -0.5 -0.5 0.3 0.4 -0.5 -0.5 0.6 0.6 1.3
Leg fat mass (left) 0.2 0.8 4.9 -0.2 -0.3 0.8 0.8 -0.6 -0.3 0.6 1.0 2.2 -0.3 -1.5 0.3 -0.0 0.2
Arm predicted mass (left) 0.4 1.9 7.0 -1.0 -1.4 1.3 0.1 -1.8 -1.1 -0.2 -0.6 1.2 -1.1 -2.6 -1.4 -1.2 -2.0