Hub : Genes

TMEM229B

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.2550	0.0770	1.5e-03	0.011	NA	0.056	NA	0.032	8.0e-02	NA	7.1e-04	NA	8.2e-03
2	GTEx	Colon Transverse	0.2810	0.0720	1.4e-04	0.163	NA	0.108	NA	0.155	3.5e-08	NA	8.5e-06	NA	8.0e-08
3	GTEx	Lung	0.1557	0.0593	5.2e-03	-0.001	NA	0.002	NA	-0.003	4.3e-01	NA	2.0e-01	NA	6.0e-01
4	GTEx	Pancreas	0.4430	0.0820	6.5e-06	0.247	NA	0.200	NA	0.229	7.7e-11	NA	7.0e-09	NA	4.7e-10
5	GTEx	Spleen	0.5710	0.0900	1.4e-05	0.199	NA	0.273	NA	0.307	7.9e-06	NA	1.1e-07	NA	1.3e-08
6	GTEx	Thyroid	0.1430	0.0480	3.2e-04	0.099	NA	0.062	NA	0.073	5.1e-08	NA	1.8e-05	NA	2.9e-06
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0727	0.0227	2.3e-05	0.055	0.044	0.041	NA	0.046	8.3e-07	8.6e-06	2.1e-05	NA	5.9e-06
8	TCGA	Lung Adenocarcinoma	0.0587	0.0251	2.0e-03	0.046	0.016	0.031	NA	0.035	4.4e-06	5.0e-03	1.4e-04	NA	5.3e-05
9	TCGA	Testicular Germ Cell Tumors	0.2200	0.0790	4.0e-03	-0.001	0.020	0.026	NA	0.016	3.5e-01	6.5e-02	4.0e-02	NA	8.4e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.3	0.5	1.1	-0.6	-0.0	1.0	0.1	-0.1	0.8	1.1	1.0	0.5
Bipolar Disorder or Schizophrenia	0.4	1.1	4.5	0.3	2.0	-0.3	2.1	-1.0	0.0	-0.2	-0.3	0.2
Depressed Affect (Nagel 2018)	0.5	1.0	2.4	0.6	-0.9	0.3	-0.8	0.3	-0.6	1.4	1.6	1.4
Depression (Nagel 2018)	0.7	1.1	3.7	0.6	1.0	-0.3	1.1	-1.9	-1.9	-0.4	-0.2	-0.1
Intelligence (Savage-Jansen 2018)	1.2	3.8	9.6	-0.9	-3.1	-1.1	-2.6	1.6	1.3	1.9	2.0	1.8
Neuroticism (Nagel 2018)	0.5	1.3	3.3	-0.2	-1.5	0.2	-1.5	0.2	-0.1	1.6	1.8	0.9
Schizophrenia (2018)	1.1	2.2	6.9	0.9	2.6	-1.1	2.6	-1.1	-0.6	-1.1	-1.2	-0.2
Schizophrenia vs Biploar Disorder	0.3	0.4	1.4	-0.4	0.2	0.2	0.1	-0.6	-1.2	-1.0	-1.0	0.0
Worry (Nagel 2018)	0.3	0.5	1.5	0.6	-0.8	0.4	-0.6	-0.3	0.7	1.1	1.2	0.3
Alzheimer’s Disease (in mother)	0.5	0.5	1.7	-0.5	-1.0	1.3	-0.7	0.2	-0.3	0.8	0.7	-0.0
Alzheimer’s Disease (in father)	0.4	0.4	3.4	-0.1	-0.4	-0.3	-0.3	-0.1	0.2	-0.1	-0.3	-1.8
Alzheimer’s Disease (including proxy)	0.5	0.7	2.6	-0.1	-1.6	0.8	-0.8	0.6	0.2	0.7	0.6	-0.9
Crohns Disease (2017)	4.2	9.2	20.3	2.4	3.4	-0.9	3.2	-2.7	0.8	-4.5	-4.5	-2.4
Irritable Bowel Disease (IBD)	1.8	4.4	10.8	1.9	2.3	-0.4	2.1	-1.1	1.2	-2.9	-3.3	-2.0
Ulcerative Colitis (UC)	0.1	0.3	0.5	0.5	0.5	0.3	0.4	0.5	0.5	-0.3	-0.7	-0.6
Major Depression (MDD)	1.1	1.3	4.3	-0.1	-0.8	-0.2	-0.8	1.5	-0.3	2.1	1.8	0.6
Reaction Time	4.9	9.3	15.2	-2.8	-3.5	0.8	-3.6	3.6	-0.9	3.9	3.8	2.4
Verbal and Numeric Reasoning (VNR)	0.6	1.4	3.6	-0.4	-1.9	0.1	-1.7	1.2	1.1	1.0	1.1	1.1
Breast Cancer	2.2	5.2	11.4	-2.5	-2.9	-3.4	-2.9	-0.4	2.0	1.7	1.9	-1.3
Ovarian Cancer	0.2	0.3	1.2	1.1	0.5	-0.3	0.4	0.2	-0.1	0.4	0.4	-0.7
Prostate Cancer	0.6	0.8	3.7	0.3	0.1	-0.1	0.3	-1.9	0.3	-1.4	-1.1	-0.3
Age at First Birth	0.5	0.8	2.3	1.0	1.5	-0.4	1.1	-0.5	0.5	-0.8	-0.8	-0.8
Bipolar Disorder (2011)	0.2	0.2	0.5	0.3	0.4	-0.5	0.5	-0.4	0.7	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.3	0.4	1.3	-0.1	0.3	-0.3	0.1	-0.0	1.1	-0.8	-0.8	-0.8
Coronary Artery Disease (CAD)	2.3	2.7	18.4	-0.6	0.6	-4.3	0.6	-1.4	1.4	-0.7	-0.4	-0.2
Crohns Disease (2012)	2.7	4.3	10.5	1.9	1.5	-1.5	1.5	-2.3	1.3	-3.2	-3.2	-1.1
Mean Putamen Volume	1.1	1.2	3.8	-0.5	-0.5	0.7	-0.6	0.5	-1.9	1.5	1.7	0.6
Fasting Glucose	0.4	0.4	1.3	0.7	0.8	0.8	-0.1	0.7	-1.1	-0.5	-0.2	-0.5
HbA1C	0.5	0.6	4.5	-2.1	-0.2	-0.3	-0.5	-0.1	-0.2	-0.0	0.3	-0.2
HDL Cholesterol	0.1	0.2	1.6	-0.2	0.0	0.4	0.0	-0.0	-0.2	-0.4	-0.4	1.2
LDL Cholesterol	0.5	0.8	1.6	1.1	1.3	0.6	1.2	0.1	0.6	-0.8	-0.9	-0.6
Lupus	0.7	1.0	2.9	-1.0	-0.1	1.0	-0.4	1.7	-0.6	1.2	0.9	1.3
Neuroticism (2016)	0.2	0.3	0.6	-0.4	0.7	-0.4	0.6	-0.7	0.5	-0.8	-0.7	-0.2
Primary Biliary Cirrhosis	0.5	0.7	1.9	-1.2	0.6	-0.8	0.6	-1.4	-0.3	-1.1	-0.7	-0.4
Rheumatoid Arthritis	0.2	0.3	1.8	-0.4	-0.1	1.3	-0.1	0.5	-0.7	0.1	-0.2	0.3
Schizophrenia (2014)	1.3	2.8	7.7	0.4	2.8	-0.7	2.7	-2.0	-0.7	-1.5	-1.6	-0.1
Triglycerides	1.0	1.6	4.3	1.4	2.1	0.2	1.7	-0.9	1.1	-1.3	-1.3	-0.5
Type 2 Diabetes (T2D) (2012)	1.0	1.2	2.2	-0.7	-1.4	0.2	-1.3	1.2	1.5	1.3	1.1	0.5
Ulcerative Colitis	0.1	0.2	1.1	-0.2	-0.2	0.5	-0.2	0.1	1.1	-0.2	-0.1	0.5
Blood Eosinophil Count	0.1	1.1	6.0	-0.4	-0.5	0.7	-0.4	0.4	-2.4	0.3	0.3	1.6
Blood Platelet Count	0.6	7.2	35.2	-1.9	-1.7	-5.9	-1.6	-3.5	2.1	1.1	1.3	-0.4
Blood Red Count	0.5	4.8	21.0	1.1	-0.8	4.1	-0.9	4.6	0.6	0.8	0.6	1.1
Blood White Count	0.6	4.2	11.3	0.1	-1.8	2.6	-1.8	3.4	-1.4	2.3	2.2	1.4
Heel T-Score	0.2	1.3	5.2	1.6	0.8	-2.3	0.5	-0.5	-1.5	0.2	0.3	-0.2
BMI	0.9	5.1	12.0	-2.0	-3.1	1.1	-3.2	3.5	1.3	1.8	1.7	0.8
Height	0.1	2.3	6.2	-0.4	-2.0	-2.2	-1.9	-0.4	-0.1	1.0	0.5	-2.5
Waist Hip Ratio (WHR)	0.4	2.0	4.6	1.3	2.1	-0.1	2.1	-1.3	0.1	-1.6	-1.7	0.1
Systolic Blood Pressure	0.9	4.5	9.5	1.9	3.1	-1.0	2.9	-1.9	3.1	-1.5	-1.3	0.8
Smoking Status	0.7	1.6	3.3	0.7	1.8	1.2	1.7	-0.8	0.3	-1.5	-1.7	-0.9
Allergy or Eczema	0.7	1.8	3.8	-1.6	-1.9	-0.2	-1.9	1.9	1.0	0.7	0.4	0.9
Cardiovascular Disease	1.0	3.4	6.2	2.4	2.5	-1.5	2.4	-2.2	1.3	-1.4	-1.5	0.4
Hypothyroidism (self reported)	0.3	0.7	3.3	0.6	0.7	-0.9	0.6	-0.7	0.1	-0.4	-0.4	-1.8
Respiratory disease	3.0	6.6	11.8	-1.6	-3.0	1.4	-3.0	3.0	1.9	2.7	2.4	3.4
Type 2 Diabetes (T2D) (2018)	1.1	2.1	3.8	-1.9	-1.9	0.8	-1.8	0.5	-1.0	1.2	1.6	-1.3
Lung FEV1/FVC ratio	0.2	0.8	4.0	-0.3	-1.1	-2.0	-0.9	-0.3	0.5	0.7	0.6	-0.0
Lung FVC	0.6	3.0	8.9	0.5	1.7	-1.2	1.7	-3.0	-0.4	-2.4	-2.0	-0.5
Neuroticism	1.1	2.7	5.4	-0.9	-2.3	0.4	-2.3	1.5	1.3	2.0	2.1	-0.4
Chronotype (morning person)	0.3	0.6	1.8	-0.0	-1.0	1.3	-0.9	1.1	0.6	0.3	0.3	-0.6
Hair Pigment	0.0	1.4	4.3	-1.8	-0.5	-0.8	-0.5	-2.1	-0.0	-0.2	-0.1	-1.9
Tanning	0.1	1.8	9.6	1.0	0.5	3.1	0.6	1.2	-1.4	-0.4	-0.7	1.0
Hand grip strength (left)	0.6	1.5	11.0	0.4	-0.1	-0.7	-0.0	-0.9	0.0	-0.8	-0.9	-3.3
Number of treatments/medications taken	0.9	1.7	4.9	0.1	2.2	-0.5	2.1	-1.6	-1.1	-0.8	-0.8	0.8
Average weekly spirits intake	2.6	3.2	6.4	-1.0	-2.4	-0.5	-2.5	2.0	-1.2	2.2	2.2	0.1
Sensitivity / hurt feelings	0.6	1.0	2.6	-1.6	-0.9	-0.8	-0.9	0.3	1.6	0.6	0.8	-1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.2	1.2	0.5	1.5	0.5	-0.8	-0.9	-0.4	-0.4	-0.0
Hearing difficulty/problems: Yes	1.2	1.9	7.2	-2.7	-1.6	-1.3	-1.9	0.7	0.8	0.2	0.3	-0.7
Relative age of first facial hair	0.3	0.6	1.8	-1.4	-0.9	0.5	-0.9	0.7	0.5	-0.2	-0.3	-1.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	-0.1	-0.3	0.1	-0.2	0.1	0.5	0.5	0.5	-0.4
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.0	-0.4	0.2	-1.0	0.3	-0.2	-0.8	-0.8	-0.7	0.8
Ever had hysterectomy (womb removed)	0.6	0.7	2.2	-1.1	-0.7	-0.2	-0.8	0.6	-1.5	0.6	0.7	-0.7
Systolic blood pressure, automated reading	0.5	1.3	2.4	-0.3	1.3	-1.6	1.1	-1.6	0.4	-1.2	-0.9	1.3
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.5	-0.9	-1.2	0.7	-1.1	0.9	0.6	0.7	0.4	0.6
Angina	0.7	1.0	3.8	-0.2	0.3	-0.9	0.1	-0.3	2.0	-0.9	-1.1	1.4
Medication for hormone replacement therapy	0.3	0.3	0.6	0.6	0.7	0.2	0.8	0.5	-0.5	-0.3	-0.2	-0.6
Vitamin and mineral supplements	0.6	0.8	2.1	-0.4	-1.3	-0.1	-1.5	1.0	0.6	0.9	0.8	-0.2
Supplements: Zinc	0.4	0.4	1.2	-1.1	-1.1	-0.0	-1.0	-0.1	0.6	0.2	0.2	0.1
Medication: Co-codamol	1.3	1.5	3.2	1.1	1.7	-0.4	1.8	-1.4	-1.0	-1.2	-1.1	-1.0
Medication: Metformin	3.6	5.1	9.6	-2.5	-3.1	0.5	-3.1	2.0	0.2	2.7	2.8	0.9
Diabetes (father)	2.3	2.8	4.6	-1.7	-2.1	1.0	-2.1	1.9	1.1	1.6	1.4	1.7
Diabetes (mother)	0.2	0.3	0.9	0.5	-0.3	0.0	-0.3	0.8	0.9	0.2	0.1	0.7
Severe depression (siblings)	2.6	2.9	13.2	-3.6	-1.9	-0.5	-1.8	0.2	-1.2	1.2	1.2	1.3
Pack years adult smoking proportion	0.1	0.1	0.4	-0.2	0.1	-0.2	-0.0	0.2	-0.0	0.5	0.6	0.2
Impedance of leg (right)	0.9	4.4	11.6	0.4	3.4	-0.2	3.4	-2.4	-1.5	-2.0	-1.9	-0.6
Leg fat-free mass (left)	1.0	5.5	15.8	-2.0	-4.0	-0.9	-4.0	2.1	1.7	1.8	1.7	0.0
Trunk fat percentage	0.3	1.3	4.2	-0.9	-1.1	-0.2	-1.2	2.1	0.9	0.7	0.5	1.5
Hand grip strength (right)	0.7	1.8	9.0	1.1	0.1	-2.2	0.1	-1.0	-0.3	-0.3	-0.4	-3.0
Townsend deprivation index at recruitment	3.4	4.7	12.9	-0.9	-1.6	0.2	-1.6	3.0	-1.5	3.6	3.5	-0.4
Current tobacco smoking	2.2	3.5	8.3	2.2	2.9	2.1	2.8	-0.3	-0.2	-1.5	-1.7	-1.0
Average weekly fortified wine intake	0.7	0.9	3.8	0.3	-1.2	-1.9	-1.3	-0.0	-0.1	0.3	0.5	0.5
Maternal smoking around birth	0.5	0.7	1.8	-0.7	-0.7	0.2	-0.9	1.4	-1.0	0.7	0.8	-0.8
Fed-up feelings	1.0	1.8	5.1	-0.2	-1.2	1.4	-1.2	1.4	-0.0	1.4	1.5	2.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	4.0	0.3	1.3	-0.0	1.2	-2.0	-1.3	-1.4	-1.4	-0.5
Relative age voice broke	1.1	1.6	3.6	-1.3	-0.1	-0.1	0.0	-1.1	1.9	-1.7	-1.6	-1.6
Taking other prescription medications	0.4	0.7	2.2	-1.5	-0.5	0.5	-0.5	0.7	-0.1	1.0	0.8	1.1
Age when periods started (menarche)	1.0	2.4	5.6	0.2	2.4	0.5	2.3	-1.7	-1.4	-1.6	-1.8	-0.5
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.8	0.3	0.0	-0.9	-0.1	0.2	-0.9	-0.7	-0.5	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.6	-1.0	-1.2	-1.1	-1.3	-0.2	-0.1	0.5	0.5	-0.4
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.5	-0.6	-1.8	-1.6	-1.9	0.4	0.3	0.3	0.3	-0.3
Qualifications: CSEs or equivalent	1.0	1.3	3.0	1.7	1.3	0.7	1.2	-0.5	-0.9	-1.3	-1.4	0.1
Serious illness, injury or assault to yourself	1.7	2.1	4.0	0.4	1.8	-0.0	1.6	-1.4	-1.6	-2.0	-1.8	-1.0
High blood pressure	1.1	3.0	6.1	2.3	2.4	-1.5	2.5	-2.2	0.4	-1.2	-1.2	-0.1
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.4	-1.2	-1.0	-0.6	-1.1	0.7	1.0	0.1	-0.1	0.2
Multivitamins +/- minerals	0.2	0.3	0.7	0.4	0.7	0.3	0.8	-0.7	-0.9	-0.3	-0.1	0.2
Stomach or abdominal pain in last month	1.3	1.6	4.1	0.2	1.7	-2.0	1.6	-1.2	-1.8	-0.5	-0.3	0.6
Supplements: Glucosamine	3.0	4.0	7.8	2.3	2.6	0.3	2.8	-1.7	-2.3	-1.8	-2.0	0.4
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	4.2	-2.0	-1.6	-0.1	-1.5	0.9	0.2	1.9	1.9	-0.6
Medication: Atenolol	1.1	1.4	4.7	-0.4	0.0	-2.2	0.1	-1.6	1.7	-0.7	-0.4	1.1
Medication: Levothyroxine sodium	0.3	0.5	2.9	-0.7	-0.1	-0.2	-0.1	-0.6	0.3	-0.3	-0.4	-1.7
Sitting height	0.5	3.4	8.9	0.3	-3.0	-0.4	-2.8	1.6	1.6	2.0	2.0	-0.8
Chronic bronchitis/emphysema (father)	1.2	1.4	3.4	0.1	-0.7	-1.7	-0.8	1.0	0.4	1.8	1.8	0.8
High blood pressure (mother)	2.9	4.0	12.4	1.0	1.1	-3.5	1.0	-2.8	1.3	-2.4	-2.2	-1.0
Body mass index (BMI)	0.6	2.7	6.1	-1.3	-2.3	-0.1	-2.4	2.5	0.5	1.3	1.2	1.5
Impedance of leg (left)	0.7	3.6	10.5	1.0	3.2	-0.1	3.2	-1.9	-1.5	-1.5	-1.3	-0.9
Leg predicted mass (left)	1.1	5.7	16.7	-2.1	-4.1	-1.0	-4.1	2.1	1.7	1.8	1.7	0.1
Trunk fat mass	0.6	2.6	5.9	-1.5	-2.2	-0.4	-2.2	2.4	0.6	1.4	1.2	1.4
Waist circumference	0.5	2.0	5.9	-0.9	-1.7	-0.2	-1.8	2.4	0.8	1.0	0.8	1.7
Number of incorrect matches in round	0.7	1.1	3.4	0.2	0.9	-0.2	0.9	-1.8	-1.8	-1.1	-1.0	-0.2
Past tobacco smoking	0.5	1.0	6.2	2.5	0.7	0.6	0.8	-0.0	-0.8	-0.3	-0.2	-0.7
Alcohol usually taken with meals	0.7	1.2	2.5	-0.0	-1.4	-0.4	-1.6	1.5	0.6	0.9	0.9	1.1
Nervous feelings	0.2	0.3	0.9	-0.3	-0.3	0.7	-0.2	-0.1	-0.4	0.9	1.0	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	2.0	0.3	0.4	1.4	0.4	-1.1	0.2	-0.5	-0.3	-0.2
Hearing difficulty/problems with background noise	0.6	1.0	2.7	-1.6	-0.5	-1.5	-0.7	-0.0	1.4	-0.6	-0.5	-1.0
Hair/balding pattern: Pattern 2	3.4	4.3	7.5	-0.6	-2.7	2.1	-2.6	2.4	-1.1	1.8	2.0	2.2
Had menopause	0.2	0.3	1.3	0.9	-0.0	-1.2	-0.0	0.0	0.6	-0.3	-0.4	-0.1
Had other major operations	0.3	0.4	1.9	1.4	-0.4	0.7	-0.7	0.2	-0.3	0.4	0.2	0.0
Forced vital capacity (FVC)	0.5	2.1	7.8	0.7	0.6	-2.0	0.6	-2.8	-0.9	-1.1	-1.1	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.3	-0.5	-1.1	-0.8	-1.1	-0.4	0.2	0.1	0.1	-1.1
Ever unenthusiastic/disinterested for a whole week	3.1	3.7	6.2	1.6	2.4	-1.7	2.3	-2.5	0.0	-2.2	-2.4	0.1
Qualifications: None of the above	0.8	1.6	4.7	0.9	2.2	0.5	2.0	-0.4	-0.8	-1.1	-1.3	1.0
Financial difficulties in last 2 years	0.5	0.6	2.0	0.3	-0.3	0.2	-0.3	1.1	-0.3	1.4	1.4	0.1
Mouth/teeth dental problems	1.2	1.9	4.5	1.5	1.2	0.4	1.2	-1.4	1.2	-1.5	-1.3	-2.1
Heart attack	0.7	0.9	2.9	1.2	0.8	-1.7	0.9	-0.5	1.2	0.5	0.6	0.2
Allergy	0.4	0.9	1.9	1.3	1.2	1.0	1.2	-0.2	-1.4	-0.3	-0.2	-0.9
Pain all over the body in last month	0.2	0.3	0.8	0.3	-0.3	-0.3	-0.3	-0.9	-0.8	-0.5	-0.3	0.4
Diabetes (self-reported)	2.1	3.3	7.2	-1.7	-2.7	0.6	-2.5	1.4	-1.0	2.1	2.2	-0.9
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.9	-1.4	-0.3	1.1	-0.2	-0.4	-0.9	-0.2	-0.1	0.5
Medication: Ramipril	1.1	1.4	4.0	1.3	0.2	2.0	0.1	1.7	1.8	0.7	0.6	0.3
Medication: Simvastatin	1.1	1.6	3.5	-1.0	-1.8	-1.3	-1.9	0.9	0.1	0.5	0.7	1.7
Fluid intelligence score	1.0	2.1	5.9	-1.1	-2.1	-1.2	-1.9	0.6	2.4	0.9	0.8	0.8
Illnesses of siblings	0.7	1.0	2.7	1.6	-0.6	1.0	-0.4	1.2	-0.3	1.3	1.1	0.3
Neuroticism score	0.5	1.1	2.7	-0.3	-1.2	-0.6	-1.2	0.5	1.6	1.4	1.3	-0.3
Weight	0.8	4.0	10.6	-1.7	-3.3	-0.8	-3.3	2.4	0.5	1.7	1.5	0.7
Impedance of arm (right)	1.3	6.1	16.3	2.3	4.0	0.8	4.0	-2.1	0.6	-2.5	-2.5	-0.3
Arm fat percentage (right)	0.3	1.4	5.3	-0.3	-0.9	0.9	-1.0	2.3	0.8	0.7	0.3	1.8
Trunk fat-free mass	1.1	6.6	19.4	-2.2	-4.4	-1.2	-4.4	1.9	0.6	2.3	2.2	-0.1
Hip circumference	0.9	3.9	8.8	-1.1	-2.9	0.2	-3.0	2.8	0.5	1.8	1.8	1.2
Time employed in main current job	0.9	1.0	3.3	-1.8	-1.1	-0.5	-1.0	-0.2	-0.8	1.1	1.3	-0.5
Alcohol intake versus 10 years previously	0.6	0.9	2.8	-0.6	-0.8	1.7	-0.7	1.5	-0.9	0.7	0.4	-0.0
Father’s age at death	1.5	2.0	5.2	-0.7	-2.3	0.4	-2.2	2.0	-0.7	0.8	1.3	0.4
Worrier / anxious feelings	0.9	1.7	3.5	-1.4	-1.5	0.2	-1.5	0.0	1.5	1.5	1.9	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.9	0.2	0.3	0.5	0.4	-0.4	-0.9	0.1	0.2	0.6
Falls in the last year	0.2	0.3	0.7	-0.2	0.5	-0.2	0.6	-0.6	-0.5	-0.7	-0.7	-0.8
Hair/balding pattern: Pattern 3	0.8	1.2	5.3	-0.3	1.1	-2.3	0.9	0.1	0.7	0.2	0.2	-1.8
Number of live births	0.1	0.1	1.0	1.0	0.2	-0.4	0.2	0.0	0.2	-0.1	0.1	-0.1
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	7.7	1.0	0.5	-2.2	0.6	-2.8	-0.9	-0.8	-0.8	-1.4
Pulse rate	0.2	0.3	1.3	1.1	0.2	-0.2	0.2	-0.3	-1.0	-0.5	-0.4	-0.3
Happiness	0.7	0.8	1.9	0.5	1.1	1.3	1.1	-1.4	0.5	-0.7	-0.6	-0.1
Noisy workplace	1.6	1.9	4.7	-0.3	-1.0	2.2	-1.1	1.8	-2.0	1.4	1.1	-0.1
Qualifications: A levels/AS levels or equivalent	1.8	4.0	8.3	-1.4	-2.9	-0.8	-2.9	1.5	1.9	2.2	2.0	-1.5
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	5.3	-1.1	0.4	-1.2	0.3	-2.0	0.2	-2.2	-2.1	-2.3
Mouth/teeth dental problems: Dentures	0.6	1.0	6.1	-2.5	-0.5	0.3	-0.5	-0.1	-1.0	-0.0	-0.2	1.2
Asthma	1.4	2.8	8.2	-1.6	-1.6	0.8	-1.6	1.4	2.1	1.1	1.0	2.9
Medication: Ibuprofen (e.g. Nurofen)	2.6	3.3	7.5	0.6	2.6	0.8	2.4	-1.3	0.9	-2.5	-2.7	-0.0
Medication: Cholesterol lowering	0.7	1.0	4.5	-1.0	-0.8	-1.4	-0.9	0.1	2.1	-0.3	0.0	0.5
Depression (self-reported)	1.3	1.5	5.2	-0.1	-0.5	2.3	-0.4	1.2	-1.0	1.8	1.5	0.6
Medication: Lansoprazole	1.0	1.1	3.8	-1.7	-0.8	0.9	-0.9	-0.1	-1.9	-0.3	-0.4	-0.9
Prospective memory result	1.0	1.2	3.7	-0.5	1.9	1.0	1.6	-0.9	-1.6	0.1	-0.0	0.3
Lung cancer (father)	0.7	0.8	4.6	0.5	0.8	0.7	0.9	-0.6	-2.1	0.1	-0.0	-0.3
Illnesses of mother	0.8	0.9	2.9	1.0	-0.1	1.3	-0.2	1.7	-0.4	1.2	1.0	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	4.8	0.9	0.6	-1.3	0.7	-2.2	0.5	-0.9	-0.9	-0.8
Pulse wave Arterial Stiffness index	0.2	0.3	0.8	-0.4	-0.3	-0.8	-0.2	0.9	0.1	0.3	0.5	0.6
Impedance of arm (left)	1.2	5.6	14.1	2.1	3.7	0.3	3.8	-2.4	0.2	-2.4	-2.5	0.1
Arm fat mass (right)	0.7	2.9	6.3	-1.3	-2.4	-0.3	-2.5	2.4	1.0	1.3	1.1	1.6
Trunk predicted mass	1.2	6.8	20.0	-2.3	-4.5	-1.2	-4.5	2.0	0.6	2.3	2.2	-0.1
Standing height	0.2	1.6	4.3	-0.7	-2.1	-1.6	-1.9	0.0	0.3	0.8	0.7	-1.5
Length of working week for main job	1.7	1.9	5.1	-0.2	0.9	-1.9	0.8	-2.3	1.0	-1.0	-1.1	-1.9
Exposure to tobacco smoke at home	0.9	1.0	3.6	-0.6	-1.0	0.7	-1.1	0.8	-1.9	0.7	0.9	0.8
Breastfed as a baby	0.5	0.6	1.4	-0.7	-1.1	-0.1	-1.2	0.6	0.1	0.6	0.5	1.1
Tense / ‘highly strung’	0.2	0.4	1.3	1.2	0.5	0.5	0.5	-0.1	1.1	0.1	-0.2	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	2.5	-0.5	-1.0	1.5	-0.8	1.5	-0.8	1.6	1.3	-0.6
Hair/balding pattern: Pattern 4	0.9	2.1	4.5	1.7	2.0	2.1	2.0	0.1	-1.2	-0.8	-1.0	0.1
Birth weight of first child	0.4	0.7	2.3	1.1	0.4	-0.1	0.5	-0.3	0.2	-1.3	-1.5	-0.7
Peak expiratory flow (PEF)	0.2	0.5	2.6	1.1	0.4	-0.5	0.5	-1.6	-0.5	-0.3	-0.4	-0.0
Pulse wave reflection index	0.1	0.1	0.3	0.0	0.5	-0.4	0.4	-0.3	0.4	-0.2	-0.1	0.5
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.7	-0.2	0.8	-0.9	0.9	-1.3	0.5	-1.1	-1.0	-0.6
Loud music exposure frequency	0.9	1.0	2.7	-0.4	0.5	-0.6	0.6	-1.2	1.6	-1.0	-1.0	-1.4
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	8.0	-1.3	-1.8	-2.8	-1.9	0.2	2.7	0.9	1.0	-0.5
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.6	0.2	-0.7	0.0	-0.7	1.6	-0.7	1.2	1.1	0.5
Blood clot in the leg (DVT)	0.8	1.1	4.8	0.4	0.2	-0.3	0.2	-1.3	-0.4	-1.1	-1.1	-2.2
Medication: Paracetamol	4.4	7.4	14.1	1.7	3.8	-2.0	3.7	-3.1	-0.4	-3.2	-3.4	-0.7
Headache pain in last month	2.0	3.5	7.3	0.5	1.7	-0.1	1.7	-2.3	-1.7	-2.6	-2.7	-1.8
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	2.6	-0.3	-1.2	0.6	-1.0	0.6	-1.6	1.0	0.8	-0.6
Glaucoma (self-reported)	0.6	0.7	2.7	-0.9	-0.5	-1.6	-0.5	-1.0	-0.2	0.1	-0.2	-1.2
Gout (self-reported)	1.7	2.4	4.8	1.5	1.8	2.1	1.9	-1.0	-2.2	-0.9	-1.0	-0.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	2.8	0.1	0.6	-0.7	0.5	-0.6	-0.1	-0.4	-0.4	-1.7
Medication: Amlodipine	0.5	0.7	1.7	-1.3	-0.4	-0.8	-0.5	-0.8	0.3	-1.0	-0.9	-1.0
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.1	-1.5	-1.2	0.7	-1.2	0.6	0.6	0.7	0.5	0.6
Birth weight	0.4	0.8	1.9	1.4	0.8	1.2	0.7	0.3	0.0	-0.9	-0.8	-1.3
Chronic bronchitis/emphysema (mother)	0.6	0.8	4.5	0.3	0.2	0.5	0.2	-0.7	-2.1	-0.9	-0.6	0.1
High blood pressure (siblings)	0.4	0.6	1.5	-1.2	0.6	-1.0	0.4	-0.7	-0.1	-0.9	-0.8	0.2
Forced vital capacity (FVC), Best measure	0.4	1.4	5.2	0.7	0.8	-1.2	0.8	-2.3	0.4	-1.4	-1.3	-0.8
Body fat percentage	0.3	1.3	4.7	-1.1	-1.1	0.1	-1.2	2.2	0.3	0.8	0.6	1.6
Leg fat percentage (right)	0.4	1.4	3.6	-1.9	-1.2	-0.5	-1.3	1.6	-1.0	0.9	0.7	0.9
Arm fat-free mass (right)	1.7	8.8	24.7	-2.8	-5.0	-1.7	-5.0	2.3	0.9	2.5	2.6	0.1
Exposure to tobacco smoke outside home	0.6	0.8	2.7	-0.0	0.3	0.6	0.1	1.0	0.5	1.7	1.3	0.9
Comparative body size at age 10	0.4	1.2	2.2	0.2	0.8	-1.3	0.7	-1.5	1.3	-1.5	-1.3	-0.3
Number of full brothers	0.2	0.3	0.6	0.6	0.2	0.8	0.1	0.4	-0.6	0.6	0.1	0.7
Worry too long after embarrassment	0.9	1.5	4.0	-1.5	-0.9	-1.6	-0.9	-0.7	1.4	-0.3	-0.0	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.7	-1.0	0.2	1.6	0.1	0.4	-0.2	-0.1	-0.4	0.6
Wheeze or whistling in the chest in last year	0.8	1.3	4.2	-0.1	-0.1	0.5	-0.2	2.1	1.3	1.5	1.1	1.6
Number of children fathered	0.7	0.8	2.2	-0.1	0.9	0.3	1.0	-1.1	-0.5	-1.5	-1.3	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.0	-1.6	0.1	-0.5	-0.0	-1.7	-1.1	-0.4	-0.3	-0.7
Age at first live birth	0.7	1.2	3.8	0.5	0.4	0.6	0.4	-1.1	2.0	-1.4	-1.5	-1.0
Pulse wave peak to peak time	0.3	0.3	1.0	0.6	0.3	0.7	0.2	-1.0	0.1	-0.3	-0.5	-0.7
Health satisfaction	0.3	0.4	1.2	-0.9	0.2	0.9	0.2	0.7	0.1	0.3	0.5	1.1
Shortness of breath walking on level ground	0.5	0.6	2.3	-0.1	0.8	0.7	0.9	0.4	-1.0	0.1	0.3	1.5
Qualifications: College or University degree	0.4	1.3	4.9	-0.9	-0.5	-1.5	-0.6	-1.2	0.3	-0.9	-0.7	-2.2
Eye problems/disorders: None of the above	2.3	2.6	6.5	1.7	1.9	2.5	1.9	0.3	0.1	-1.3	-1.6	-1.6
Mouth/teeth dental problems: Loose teeth	1.1	1.3	4.8	-0.7	-0.7	0.3	-0.7	0.5	-2.2	1.1	1.2	1.6
Emphysema/chronic bronchitis	1.3	1.5	5.1	0.5	-0.6	1.8	-0.6	0.7	2.3	0.0	-0.1	1.9
Medication for pain relief, constipation, heartburn	1.9	3.3	8.1	-0.9	-2.9	0.8	-2.6	1.4	0.4	2.2	2.4	0.6
Neck or shoulder pain in last month	1.6	2.3	5.0	0.6	2.2	0.7	2.2	-1.1	1.0	-1.9	-2.1	-0.6
Medication: Blood pressure	0.8	1.4	3.3	1.1	1.8	-0.6	1.7	-1.0	1.8	-0.8	-0.4	0.1
Angina (self-reported)	0.6	0.8	3.7	-0.5	-0.1	-0.4	-0.2	-0.2	1.9	-0.7	-0.8	1.4
Migraine (self-reported)	2.2	2.8	6.2	1.6	1.9	-0.2	2.1	-1.7	0.5	-1.6	-1.5	-2.5
Medication: Ibuprofen	1.7	2.1	4.8	0.6	2.2	0.6	2.0	-0.4	0.5	-1.9	-2.2	-0.3
Medication: Allopurinol	0.5	0.6	1.7	1.0	0.3	1.2	0.4	0.1	-1.3	0.0	0.1	1.1
Medication: Omeprazole	0.5	0.6	1.7	-0.6	-0.0	-0.3	0.0	0.6	-1.1	1.3	1.2	-0.5
Medication: Seretide 50 evohaler	0.7	0.8	2.2	-1.5	-1.1	-0.7	-1.1	-0.0	1.3	-0.1	0.0	0.6
Mean time to correctly identify matches	4.1	7.9	13.8	-2.3	-2.9	1.0	-3.0	3.7	-1.5	3.7	3.6	2.2
Heart disease (mother)	1.3	1.6	3.2	0.0	1.8	-1.0	1.7	-1.3	-0.7	-0.9	-0.9	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.6	0.4	-0.1	0.4	0.1	-0.3	0.7	-0.7	-0.8	-0.6
Whole body fat mass	0.6	2.4	5.1	-1.5	-2.1	-0.4	-2.2	2.3	0.3	1.3	1.1	1.3
Leg fat mass (right)	0.7	2.6	5.2	-2.0	-2.2	-0.7	-2.3	2.1	-0.1	1.4	1.3	0.8
Arm predicted mass (right)	1.6	8.4	24.1	-2.8	-4.9	-1.9	-4.9	2.2	0.8	2.3	2.3	0.1
Pulse rate, automated reading	1.8	5.9	12.7	3.6	3.6	-1.2	3.5	-1.9	-0.9	-2.3	-2.2	-0.3
Alcohol intake frequency.	0.2	0.4	2.6	0.1	-0.4	0.0	-0.3	-0.4	-0.5	-0.5	-0.5	1.6
Comparative height size at age 10	0.6	3.4	6.8	-0.3	-2.6	-0.5	-2.6	1.6	0.6	2.4	2.5	1.5
Number of full sisters	1.4	1.7	2.9	-1.4	-1.4	1.4	-1.4	1.0	-1.1	1.1	1.0	1.7
Suffer from ‘nerves’	0.7	1.0	2.9	0.6	0.9	1.7	0.8	0.7	-1.7	0.9	0.8	-0.2
Overall health rating	0.3	0.6	2.5	-0.5	1.0	0.1	0.9	-0.1	-0.6	0.4	0.2	1.6
Chest pain or discomfort	0.4	0.6	1.7	0.0	-0.9	0.8	-0.8	1.0	1.3	0.6	0.1	0.2
Had major operations	1.0	1.2	4.0	-0.6	0.7	-2.0	0.7	-1.4	-1.5	-0.5	-0.3	0.9
Age at last live birth	0.8	1.1	6.1	0.7	0.3	0.3	0.4	-0.4	2.5	-1.1	-1.1	0.4
Family relationship satisfaction	4.3	5.3	8.3	2.9	2.6	0.8	2.6	-2.6	1.6	-2.7	-2.9	-1.0
Leg pain on walking	0.3	0.4	1.4	-0.1	0.7	-0.3	0.6	0.8	-0.2	0.3	0.5	1.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.5	0.9	0.5	1.2	0.6	-0.5	0.3	-0.8	-0.7	0.2
Commuting to job workplace: Car/motor vehicle	1.3	1.5	2.6	0.0	1.4	1.3	1.4	-1.4	0.4	-1.4	-1.6	-1.2
Illness, injury, bereavement, stress in last 2 years	2.1	2.5	11.3	-0.7	-1.7	-0.7	-1.5	1.3	3.4	1.0	0.9	1.4
Medication: Aspirin	0.1	0.1	0.2	-0.1	-0.2	-0.3	-0.2	-0.2	0.1	-0.3	-0.3	0.5
Supplements: Vitamin C	0.2	0.3	1.2	0.1	0.2	-0.1	-0.0	1.1	-1.0	0.3	0.1	-0.4
Knee pain experienced in last month	0.7	1.1	2.5	0.5	1.3	-1.6	1.2	-1.1	0.5	-0.8	-0.8	1.4
Hypertension (Self-reported)	0.7	1.8	3.4	1.8	1.8	-1.6	1.8	-1.7	0.1	-0.7	-0.7	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.0	3.5	5.4	-1.7	-2.3	0.4	-2.2	2.0	-1.9	2.3	2.3	-0.0
Illnesses of father: Heart disease	0.5	0.7	1.5	1.2	1.2	0.2	1.0	-0.2	0.6	-0.7	-0.7	-0.9
Illnesses of siblings: Diabetes	1.1	1.3	5.8	-2.4	-1.5	0.8	-1.4	0.3	-0.0	0.5	0.4	-0.8
Smoking status: Previous	0.9	1.3	6.3	-2.5	-1.1	-0.7	-1.2	-0.5	0.9	-0.4	-0.5	1.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.9	-0.1	-0.3	0.3	-0.3	0.9	0.9	0.4	0.3	-0.8
Whole body fat-free mass	1.2	6.6	19.5	-2.2	-4.4	-1.2	-4.4	2.1	1.1	2.2	2.1	-0.0
Leg fat-free mass (right)	1.2	6.5	18.3	-1.8	-4.3	-0.8	-4.3	2.4	1.8	2.1	2.1	-0.1
Arm fat percentage (left)	0.4	1.6	5.0	-0.6	-1.1	0.4	-1.2	2.2	0.7	0.9	0.5	2.1
Average weekly red wine intake	0.4	0.6	1.7	-0.9	-0.5	-0.4	-0.6	0.9	-0.0	1.3	1.3	0.2
Handedness (chirality/laterality): Left-handed	1.4	1.6	3.1	1.4	1.8	1.2	1.7	-1.4	0.1	-0.8	-1.1	-1.2
Mood swings	0.4	0.7	1.4	-0.8	-1.2	0.8	-1.1	0.3	-0.4	0.9	1.0	-0.6
Loneliness, isolation	0.2	0.3	1.1	0.9	0.5	-0.1	0.4	-1.1	0.3	0.1	-0.2	0.4
Long-standing illness, disability or infirmity	0.5	0.7	2.1	-0.7	1.0	1.4	0.9	-0.5	-1.1	0.2	0.1	1.0
Ever had bowel cancer screening	0.4	0.5	1.8	-0.5	-0.4	-1.3	-0.4	0.8	-0.6	0.7	0.7	-0.5
Diabetes diagnosed by doctor	1.3	2.1	5.7	-1.9	-2.4	0.3	-2.3	0.9	-0.0	1.1	1.3	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.0	7.6	1.2	0.7	2.8	0.7	1.4	-1.0	1.2	0.9	1.8
Friendships satisfaction	1.3	1.6	2.5	1.6	1.2	0.5	1.3	-1.1	1.2	-1.4	-1.3	1.5
Qualifications: nursing, teaching	1.8	2.8	6.4	-1.9	-2.5	-0.2	-2.5	0.7	1.4	1.2	1.1	-1.9
Commuting to job workplace: Walk	1.3	1.4	3.0	1.6	-0.6	-1.1	-0.7	1.4	-0.4	1.7	1.7	0.1
Eye problems/disorders: Cataract	1.8	2.1	6.3	-0.9	-1.3	-2.2	-1.6	0.2	0.7	0.8	1.2	2.5
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	3.2	-1.1	-1.0	-0.4	-1.2	1.8	-0.2	1.4	1.3	1.6
Medication for cholesterol	0.2	0.3	2.2	-0.1	-0.1	1.5	-0.1	0.2	0.4	-0.4	-0.3	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	3.4	-0.4	-0.1	-1.2	-0.1	-0.0	-0.0	-0.5	-0.3	1.8
Back pain experienced in last month	0.5	0.7	3.2	-0.3	-0.2	1.0	-0.2	1.1	0.8	0.1	-0.1	1.8
Mineral and other dietary supplements	2.0	2.7	5.5	-1.2	-2.3	-1.3	-2.3	1.4	1.8	1.5	1.4	-1.0
Breast cancer (self-reported)	0.7	0.8	2.4	0.1	1.1	1.6	1.1	0.8	-1.1	-0.4	-0.5	0.7
Asthma (self-reported)	1.4	2.7	8.7	-1.8	-1.5	0.9	-1.6	1.1	2.0	0.8	0.8	3.0
Osteoporosis (self-reported)	0.1	0.1	0.3	0.3	0.3	-0.0	0.3	0.3	-0.5	0.3	0.4	0.4
Osteoarthritis (self-reported)	1.3	1.6	7.5	0.9	1.6	0.2	1.7	-0.0	-2.7	-0.3	-0.1	0.7
Medication: Aspirin	0.2	0.2	0.5	-0.6	-0.7	-0.2	-0.7	-0.0	0.2	-0.2	-0.1	0.7
Medication: Gliclazide	3.2	3.6	8.2	-1.7	-2.9	-0.5	-2.8	0.7	1.8	1.6	1.8	1.8
Illnesses of father: None of the above (group 1)	0.3	0.4	1.5	0.4	0.1	0.8	0.2	0.0	-1.2	0.3	0.4	1.0
Smoking status: Current	1.8	2.9	6.9	1.7	2.6	2.1	2.5	-0.2	-0.1	-1.4	-1.5	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.1	0.6	0.4	-1.0	0.5	-1.8	0.9	-0.8	-0.7	0.6
Whole body water mass	1.2	7.1	20.7	-2.2	-4.5	-1.2	-4.5	2.2	1.2	2.2	2.1	-0.2
Leg predicted mass (right)	1.2	6.4	18.0	-1.8	-4.2	-0.8	-4.2	2.4	1.8	2.2	2.1	-0.1
Arm fat mass (left)	0.7	2.9	6.3	-1.3	-2.5	-0.4	-2.5	2.4	0.8	1.4	1.1	1.5
Number of self-reported non-cancer illnesses	0.5	0.9	2.9	0.6	1.6	1.0	1.7	-0.6	-0.6	-0.4	-0.4	-0.0
Average weekly champagne plus white wine intake	0.2	0.3	1.0	0.1	0.6	-0.8	0.5	-0.5	0.6	0.2	0.2	-1.0
Miserableness	0.2	0.3	0.5	0.7	-0.3	0.2	-0.3	0.7	-0.4	0.6	0.6	0.6
Guilty feelings	3.6	5.4	11.1	-2.2	-3.2	0.3	-3.3	2.2	-0.2	2.7	2.9	1.3
Wears glasses or contact lenses	0.5	0.6	1.5	-1.0	-1.0	-0.6	-1.1	0.7	1.2	0.0	0.1	-0.1
Ever taken oral contraceptive pill	0.4	0.5	1.7	-0.7	0.2	0.8	0.1	0.5	-0.5	0.8	0.5	-1.3
Hearing aid user	0.9	1.0	3.5	-1.9	-0.4	-0.4	-0.5	-0.9	1.2	-0.8	-0.5	1.3
Mother’s age at death	0.3	0.3	0.7	-0.2	-0.8	-0.0	-0.8	0.4	-0.5	0.8	0.7	0.5
Financial situation satisfaction	0.2	0.2	0.7	-0.0	0.3	-0.6	0.3	0.1	0.8	-0.3	-0.4	-0.7
Tinnitus: Yes, now most or all of the time	2.2	2.6	9.8	0.8	-0.4	-3.1	-0.3	-1.5	2.3	-1.6	-1.3	-0.7
Commuting to job workplace: Public transport	1.3	1.5	6.1	0.1	-1.2	-2.5	-1.3	0.6	-1.0	1.0	1.2	0.7
Eye problems/disorders: Glaucoma	0.9	1.0	3.1	-0.9	-0.4	-1.2	-0.4	-1.7	-0.3	-0.5	-0.5	-1.8
Medication: Blood pressure	0.3	0.6	1.4	-0.0	-1.0	-0.8	-1.0	0.3	0.2	1.2	0.8	0.8
Pain type(s) experienced in last month: Hip pain	0.5	0.6	3.0	0.0	1.7	0.1	1.6	-0.0	-0.1	0.0	-0.3	0.4
Supplements: Fish oil (including cod liver oil)	1.4	1.9	7.0	-0.2	1.3	1.8	1.2	-1.0	-1.3	-0.6	-0.4	2.6
High cholesterol (Self-reported)	0.5	0.8	5.0	-0.5	0.0	-2.2	-0.0	-0.8	-0.6	-0.8	-0.7	0.4
Medication: Bendroflumethiazide	0.2	0.3	0.7	-0.7	-0.7	-0.5	-0.5	-0.9	0.4	-0.0	-0.2	-0.2
Medication: Paracetamol	3.4	5.3	10.3	1.5	3.2	-0.9	3.2	-2.6	-2.0	-2.5	-2.6	-0.3
Medication: Lisinopril	0.7	0.9	1.6	-1.3	-0.2	-0.9	-0.3	-0.5	-1.2	1.0	1.1	1.2
Medication: Atorvastatin	0.9	1.2	2.5	0.5	0.5	-0.5	0.6	-1.2	1.6	-1.2	-1.3	-1.4
Illnesses of father: High blood pressure	0.5	0.6	1.9	0.6	0.8	-1.4	0.8	-0.4	0.7	-0.2	-0.5	-0.9
Alcohol drinker status: Never	0.7	0.9	3.5	-0.9	-1.1	-0.9	-0.9	-0.6	1.9	0.2	0.4	0.7
Ever smoked	0.3	0.6	2.5	-1.6	-0.1	-1.0	-0.2	-0.4	1.2	-0.2	-0.2	-0.7
Basal metabolic rate	1.1	6.3	18.4	-2.2	-4.3	-1.1	-4.3	2.2	1.1	2.1	2.0	-0.0
Leg fat percentage (left)	0.5	1.8	4.2	-1.7	-1.6	-0.4	-1.6	2.0	-0.9	1.3	1.2	0.8
Arm fat-free mass (left)	1.5	7.4	21.2	-2.3	-4.6	-1.5	-4.6	2.4	1.1	2.2	2.2	-0.1
Number of operations (self-reported)	0.3	0.5	1.1	-0.6	-0.0	-0.7	-0.2	-0.9	-0.6	-1.1	-1.0	0.1
Average weekly beer plus cider intake	1.2	1.7	3.0	-0.0	1.6	-0.7	1.7	-1.7	0.4	-1.7	-1.6	0.7
Irritability	0.2	0.4	1.2	-0.3	-0.9	-0.0	-0.9	0.4	0.4	0.6	0.3	-1.1
Risk taking	0.8	1.2	7.4	-0.9	-0.1	1.5	-0.1	0.5	0.0	0.0	-0.2	-2.7
Ever had prostate specific antigen (PSA) test	1.2	1.3	2.8	-1.7	-1.5	-1.3	-1.5	0.7	1.0	0.2	0.2	-1.2
Fractured/broken bones in last 5 years	0.5	0.6	1.8	-0.4	-0.6	0.8	-0.5	1.3	-0.9	0.6	0.7	0.7
Age started oral contraceptive pill	1.1	1.4	3.3	-1.2	-1.0	-0.9	-1.1	1.1	-0.6	1.7	1.8	-0.2
Diastolic blood pressure, automated reading	1.1	3.4	7.1	1.4	2.7	-1.2	2.5	-2.6	0.8	-1.8	-1.6	0.7
Ever depressed for a whole week	0.6	0.7	3.1	-0.1	0.1	-1.8	-0.1	-0.5	1.5	-0.4	-0.6	-0.6
Unable to work because of sickness or disability	0.3	0.3	2.0	-0.8	-0.3	-0.2	-0.3	-0.4	0.0	0.1	0.0	1.4
Commuting to job workplace: Cycle	0.3	0.4	1.6	-0.0	-0.1	-1.2	0.0	-0.7	0.0	-0.0	-0.1	-1.3
Myopia	1.1	1.6	7.1	0.1	-0.7	-1.8	-0.7	1.4	0.5	0.7	0.5	2.7
Vascular/heart problems diagnosed by doctor	1.0	2.6	6.6	-2.6	-2.1	1.4	-2.1	1.8	-1.0	0.8	0.8	-0.3
Cholesterol lowering medication	0.6	1.0	5.5	-0.9	-0.6	-2.3	-0.6	-1.0	-0.5	-0.3	-0.3	0.2
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.8	-0.7	-0.1	-0.3	-0.1	0.5	-1.4	1.3	1.3	-0.8
Pain experienced in last month	0.3	0.4	1.9	-0.2	-0.8	0.1	-0.6	0.4	-0.2	0.5	0.7	-1.4
Supplements: Calcium	0.5	0.6	1.6	-1.2	0.1	0.6	0.1	0.4	-0.2	-1.0	-1.0	1.0
Basal cell carcinoma (self-reported)	0.7	0.8	2.1	0.9	0.6	0.2	0.7	-0.8	0.4	-1.1	-1.3	-1.5
Heart attack/myocardial infarction (self-reported)	0.8	1.1	3.3	1.4	0.9	-1.8	1.0	-0.7	1.4	0.2	0.5	0.3
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	5.0	0.2	0.1	-0.8	0.0	-1.1	-0.2	-0.9	-1.0	-2.2
Heart disease (siblings)	0.9	1.1	2.6	-0.2	1.5	-0.5	1.3	-0.5	0.2	-1.6	-1.5	0.2
Alcohol drinker status: Previous	0.9	1.1	2.7	-0.3	1.0	-0.3	0.8	-1.4	-0.7	-1.6	-1.3	0.8
Pack years of smoking	0.2	0.2	0.7	-0.5	-0.2	-0.2	-0.3	0.7	0.0	0.7	0.8	0.2
Impedance of whole body	1.1	5.4	14.8	2.0	3.9	-0.1	3.9	-2.3	-0.4	-2.2	-2.2	-0.3
Leg fat mass (left)	0.8	3.0	6.2	-1.9	-2.4	-0.7	-2.5	2.4	0.0	1.6	1.4	0.8
Arm predicted mass (left)	1.5	7.5	22.0	-2.3	-4.7	-1.5	-4.7	2.4	0.9	2.1	2.1	0.1