Hub : Genes

TMEM229B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Visceral Omentum 0.2550 0.0770 1.5e-03 0.011 NA 0.056 NA 0.032 8.0e-02 NA 7.1e-04 NA 8.2e-03
2 GTEx Colon Transverse 0.2810 0.0720 1.4e-04 0.163 NA 0.108 NA 0.155 3.5e-08 NA 8.5e-06 NA 8.0e-08
3 GTEx Lung 0.1557 0.0593 5.2e-03 -0.001 NA 0.002 NA -0.003 4.3e-01 NA 2.0e-01 NA 6.0e-01
4 GTEx Pancreas 0.4430 0.0820 6.5e-06 0.247 NA 0.200 NA 0.229 7.7e-11 NA 7.0e-09 NA 4.7e-10
5 GTEx Spleen 0.5710 0.0900 1.4e-05 0.199 NA 0.273 NA 0.307 7.9e-06 NA 1.1e-07 NA 1.3e-08
6 GTEx Thyroid 0.1430 0.0480 3.2e-04 0.099 NA 0.062 NA 0.073 5.1e-08 NA 1.8e-05 NA 2.9e-06
7 TCGA Kidney Renal Clear Cell Carcinoma 0.0727 0.0227 2.3e-05 0.055 0.044 0.041 NA 0.046 8.3e-07 8.6e-06 2.1e-05 NA 5.9e-06
8 TCGA Lung Adenocarcinoma 0.0587 0.0251 2.0e-03 0.046 0.016 0.031 NA 0.035 4.4e-06 5.0e-03 1.4e-04 NA 5.3e-05
9 TCGA Testicular Germ Cell Tumors 0.2200 0.0790 4.0e-03 -0.001 0.020 0.026 NA 0.016 3.5e-01 6.5e-02 4.0e-02 NA 8.4e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.3 0.5 1.1 -0.6 -0.0 1.0 0.1 -0.1 0.8 1.1 1.0 0.5
Bipolar Disorder or Schizophrenia 0.4 1.1 4.5 0.3 2.0 -0.3 2.1 -1.0 0.0 -0.2 -0.3 0.2
Depressed Affect (Nagel 2018) 0.5 1.0 2.4 0.6 -0.9 0.3 -0.8 0.3 -0.6 1.4 1.6 1.4
Depression (Nagel 2018) 0.7 1.1 3.7 0.6 1.0 -0.3 1.1 -1.9 -1.9 -0.4 -0.2 -0.1
Intelligence (Savage-Jansen 2018) 1.2 3.8 9.6 -0.9 -3.1 -1.1 -2.6 1.6 1.3 1.9 2.0 1.8
Neuroticism (Nagel 2018) 0.5 1.3 3.3 -0.2 -1.5 0.2 -1.5 0.2 -0.1 1.6 1.8 0.9
Schizophrenia (2018) 1.1 2.2 6.9 0.9 2.6 -1.1 2.6 -1.1 -0.6 -1.1 -1.2 -0.2
Schizophrenia vs Biploar Disorder 0.3 0.4 1.4 -0.4 0.2 0.2 0.1 -0.6 -1.2 -1.0 -1.0 0.0
Worry (Nagel 2018) 0.3 0.5 1.5 0.6 -0.8 0.4 -0.6 -0.3 0.7 1.1 1.2 0.3
Alzheimer’s Disease (in mother) 0.5 0.5 1.7 -0.5 -1.0 1.3 -0.7 0.2 -0.3 0.8 0.7 -0.0
Alzheimer’s Disease (in father) 0.4 0.4 3.4 -0.1 -0.4 -0.3 -0.3 -0.1 0.2 -0.1 -0.3 -1.8
Alzheimer’s Disease (including proxy) 0.5 0.7 2.6 -0.1 -1.6 0.8 -0.8 0.6 0.2 0.7 0.6 -0.9
Crohns Disease (2017) 4.2 9.2 20.3 2.4 3.4 -0.9 3.2 -2.7 0.8 -4.5 -4.5 -2.4
Irritable Bowel Disease (IBD) 1.8 4.4 10.8 1.9 2.3 -0.4 2.1 -1.1 1.2 -2.9 -3.3 -2.0
Ulcerative Colitis (UC) 0.1 0.3 0.5 0.5 0.5 0.3 0.4 0.5 0.5 -0.3 -0.7 -0.6
Major Depression (MDD) 1.1 1.3 4.3 -0.1 -0.8 -0.2 -0.8 1.5 -0.3 2.1 1.8 0.6
Reaction Time 4.9 9.3 15.2 -2.8 -3.5 0.8 -3.6 3.6 -0.9 3.9 3.8 2.4
Verbal and Numeric Reasoning (VNR) 0.6 1.4 3.6 -0.4 -1.9 0.1 -1.7 1.2 1.1 1.0 1.1 1.1
Breast Cancer 2.2 5.2 11.4 -2.5 -2.9 -3.4 -2.9 -0.4 2.0 1.7 1.9 -1.3
Ovarian Cancer 0.2 0.3 1.2 1.1 0.5 -0.3 0.4 0.2 -0.1 0.4 0.4 -0.7
Prostate Cancer 0.6 0.8 3.7 0.3 0.1 -0.1 0.3 -1.9 0.3 -1.4 -1.1 -0.3
Age at First Birth 0.5 0.8 2.3 1.0 1.5 -0.4 1.1 -0.5 0.5 -0.8 -0.8 -0.8
Bipolar Disorder (2011) 0.2 0.2 0.5 0.3 0.4 -0.5 0.5 -0.4 0.7 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.3 0.4 1.3 -0.1 0.3 -0.3 0.1 -0.0 1.1 -0.8 -0.8 -0.8
Coronary Artery Disease (CAD) 2.3 2.7 18.4 -0.6 0.6 -4.3 0.6 -1.4 1.4 -0.7 -0.4 -0.2
Crohns Disease (2012) 2.7 4.3 10.5 1.9 1.5 -1.5 1.5 -2.3 1.3 -3.2 -3.2 -1.1
Mean Putamen Volume 1.1 1.2 3.8 -0.5 -0.5 0.7 -0.6 0.5 -1.9 1.5 1.7 0.6
Fasting Glucose 0.4 0.4 1.3 0.7 0.8 0.8 -0.1 0.7 -1.1 -0.5 -0.2 -0.5
HbA1C 0.5 0.6 4.5 -2.1 -0.2 -0.3 -0.5 -0.1 -0.2 -0.0 0.3 -0.2
HDL Cholesterol 0.1 0.2 1.6 -0.2 0.0 0.4 0.0 -0.0 -0.2 -0.4 -0.4 1.2
LDL Cholesterol 0.5 0.8 1.6 1.1 1.3 0.6 1.2 0.1 0.6 -0.8 -0.9 -0.6
Lupus 0.7 1.0 2.9 -1.0 -0.1 1.0 -0.4 1.7 -0.6 1.2 0.9 1.3
Neuroticism (2016) 0.2 0.3 0.6 -0.4 0.7 -0.4 0.6 -0.7 0.5 -0.8 -0.7 -0.2
Primary Biliary Cirrhosis 0.5 0.7 1.9 -1.2 0.6 -0.8 0.6 -1.4 -0.3 -1.1 -0.7 -0.4
Rheumatoid Arthritis 0.2 0.3 1.8 -0.4 -0.1 1.3 -0.1 0.5 -0.7 0.1 -0.2 0.3
Schizophrenia (2014) 1.3 2.8 7.7 0.4 2.8 -0.7 2.7 -2.0 -0.7 -1.5 -1.6 -0.1
Triglycerides 1.0 1.6 4.3 1.4 2.1 0.2 1.7 -0.9 1.1 -1.3 -1.3 -0.5
Type 2 Diabetes (T2D) (2012) 1.0 1.2 2.2 -0.7 -1.4 0.2 -1.3 1.2 1.5 1.3 1.1 0.5
Ulcerative Colitis 0.1 0.2 1.1 -0.2 -0.2 0.5 -0.2 0.1 1.1 -0.2 -0.1 0.5
Blood Eosinophil Count 0.1 1.1 6.0 -0.4 -0.5 0.7 -0.4 0.4 -2.4 0.3 0.3 1.6
Blood Platelet Count 0.6 7.2 35.2 -1.9 -1.7 -5.9 -1.6 -3.5 2.1 1.1 1.3 -0.4
Blood Red Count 0.5 4.8 21.0 1.1 -0.8 4.1 -0.9 4.6 0.6 0.8 0.6 1.1
Blood White Count 0.6 4.2 11.3 0.1 -1.8 2.6 -1.8 3.4 -1.4 2.3 2.2 1.4
Heel T-Score 0.2 1.3 5.2 1.6 0.8 -2.3 0.5 -0.5 -1.5 0.2 0.3 -0.2
BMI 0.9 5.1 12.0 -2.0 -3.1 1.1 -3.2 3.5 1.3 1.8 1.7 0.8
Height 0.1 2.3 6.2 -0.4 -2.0 -2.2 -1.9 -0.4 -0.1 1.0 0.5 -2.5
Waist Hip Ratio (WHR) 0.4 2.0 4.6 1.3 2.1 -0.1 2.1 -1.3 0.1 -1.6 -1.7 0.1
Systolic Blood Pressure 0.9 4.5 9.5 1.9 3.1 -1.0 2.9 -1.9 3.1 -1.5 -1.3 0.8
Smoking Status 0.7 1.6 3.3 0.7 1.8 1.2 1.7 -0.8 0.3 -1.5 -1.7 -0.9
Allergy or Eczema 0.7 1.8 3.8 -1.6 -1.9 -0.2 -1.9 1.9 1.0 0.7 0.4 0.9
Cardiovascular Disease 1.0 3.4 6.2 2.4 2.5 -1.5 2.4 -2.2 1.3 -1.4 -1.5 0.4
Hypothyroidism (self reported) 0.3 0.7 3.3 0.6 0.7 -0.9 0.6 -0.7 0.1 -0.4 -0.4 -1.8
Respiratory disease 3.0 6.6 11.8 -1.6 -3.0 1.4 -3.0 3.0 1.9 2.7 2.4 3.4
Type 2 Diabetes (T2D) (2018) 1.1 2.1 3.8 -1.9 -1.9 0.8 -1.8 0.5 -1.0 1.2 1.6 -1.3
Lung FEV1/FVC ratio 0.2 0.8 4.0 -0.3 -1.1 -2.0 -0.9 -0.3 0.5 0.7 0.6 -0.0
Lung FVC 0.6 3.0 8.9 0.5 1.7 -1.2 1.7 -3.0 -0.4 -2.4 -2.0 -0.5
Neuroticism 1.1 2.7 5.4 -0.9 -2.3 0.4 -2.3 1.5 1.3 2.0 2.1 -0.4
Chronotype (morning person) 0.3 0.6 1.8 -0.0 -1.0 1.3 -0.9 1.1 0.6 0.3 0.3 -0.6
Hair Pigment 0.0 1.4 4.3 -1.8 -0.5 -0.8 -0.5 -2.1 -0.0 -0.2 -0.1 -1.9
Tanning 0.1 1.8 9.6 1.0 0.5 3.1 0.6 1.2 -1.4 -0.4 -0.7 1.0
Hand grip strength (left) 0.6 1.5 11.0 0.4 -0.1 -0.7 -0.0 -0.9 0.0 -0.8 -0.9 -3.3
Number of treatments/medications taken 0.9 1.7 4.9 0.1 2.2 -0.5 2.1 -1.6 -1.1 -0.8 -0.8 0.8
Average weekly spirits intake 2.6 3.2 6.4 -1.0 -2.4 -0.5 -2.5 2.0 -1.2 2.2 2.2 0.1
Sensitivity / hurt feelings 0.6 1.0 2.6 -1.6 -0.9 -0.8 -0.9 0.3 1.6 0.6 0.8 -1.0
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.2 1.2 0.5 1.5 0.5 -0.8 -0.9 -0.4 -0.4 -0.0
Hearing difficulty/problems: Yes 1.2 1.9 7.2 -2.7 -1.6 -1.3 -1.9 0.7 0.8 0.2 0.3 -0.7
Relative age of first facial hair 0.3 0.6 1.8 -1.4 -0.9 0.5 -0.9 0.7 0.5 -0.2 -0.3 -1.1
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.3 -0.1 -0.3 0.1 -0.2 0.1 0.5 0.5 0.5 -0.4
Ever used hormone-replacement therapy (HRT) 0.3 0.4 1.0 -0.4 0.2 -1.0 0.3 -0.2 -0.8 -0.8 -0.7 0.8
Ever had hysterectomy (womb removed) 0.6 0.7 2.2 -1.1 -0.7 -0.2 -0.8 0.6 -1.5 0.6 0.7 -0.7
Systolic blood pressure, automated reading 0.5 1.3 2.4 -0.3 1.3 -1.6 1.1 -1.6 0.4 -1.2 -0.9 1.3
Eye problems/disorders: Diabetes related eye disease 0.6 0.7 1.5 -0.9 -1.2 0.7 -1.1 0.9 0.6 0.7 0.4 0.6
Angina 0.7 1.0 3.8 -0.2 0.3 -0.9 0.1 -0.3 2.0 -0.9 -1.1 1.4
Medication for hormone replacement therapy 0.3 0.3 0.6 0.6 0.7 0.2 0.8 0.5 -0.5 -0.3 -0.2 -0.6
Vitamin and mineral supplements 0.6 0.8 2.1 -0.4 -1.3 -0.1 -1.5 1.0 0.6 0.9 0.8 -0.2
Supplements: Zinc 0.4 0.4 1.2 -1.1 -1.1 -0.0 -1.0 -0.1 0.6 0.2 0.2 0.1
Medication: Co-codamol 1.3 1.5 3.2 1.1 1.7 -0.4 1.8 -1.4 -1.0 -1.2 -1.1 -1.0
Medication: Metformin 3.6 5.1 9.6 -2.5 -3.1 0.5 -3.1 2.0 0.2 2.7 2.8 0.9
Diabetes (father) 2.3 2.8 4.6 -1.7 -2.1 1.0 -2.1 1.9 1.1 1.6 1.4 1.7
Diabetes (mother) 0.2 0.3 0.9 0.5 -0.3 0.0 -0.3 0.8 0.9 0.2 0.1 0.7
Severe depression (siblings) 2.6 2.9 13.2 -3.6 -1.9 -0.5 -1.8 0.2 -1.2 1.2 1.2 1.3
Pack years adult smoking proportion 0.1 0.1 0.4 -0.2 0.1 -0.2 -0.0 0.2 -0.0 0.5 0.6 0.2
Impedance of leg (right) 0.9 4.4 11.6 0.4 3.4 -0.2 3.4 -2.4 -1.5 -2.0 -1.9 -0.6
Leg fat-free mass (left) 1.0 5.5 15.8 -2.0 -4.0 -0.9 -4.0 2.1 1.7 1.8 1.7 0.0
Trunk fat percentage 0.3 1.3 4.2 -0.9 -1.1 -0.2 -1.2 2.1 0.9 0.7 0.5 1.5
Hand grip strength (right) 0.7 1.8 9.0 1.1 0.1 -2.2 0.1 -1.0 -0.3 -0.3 -0.4 -3.0
Townsend deprivation index at recruitment 3.4 4.7 12.9 -0.9 -1.6 0.2 -1.6 3.0 -1.5 3.6 3.5 -0.4
Current tobacco smoking 2.2 3.5 8.3 2.2 2.9 2.1 2.8 -0.3 -0.2 -1.5 -1.7 -1.0
Average weekly fortified wine intake 0.7 0.9 3.8 0.3 -1.2 -1.9 -1.3 -0.0 -0.1 0.3 0.5 0.5
Maternal smoking around birth 0.5 0.7 1.8 -0.7 -0.7 0.2 -0.9 1.4 -1.0 0.7 0.8 -0.8
Fed-up feelings 1.0 1.8 5.1 -0.2 -1.2 1.4 -1.2 1.4 -0.0 1.4 1.5 2.3
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.5 4.0 0.3 1.3 -0.0 1.2 -2.0 -1.3 -1.4 -1.4 -0.5
Relative age voice broke 1.1 1.6 3.6 -1.3 -0.1 -0.1 0.0 -1.1 1.9 -1.7 -1.6 -1.6
Taking other prescription medications 0.4 0.7 2.2 -1.5 -0.5 0.5 -0.5 0.7 -0.1 1.0 0.8 1.1
Age when periods started (menarche) 1.0 2.4 5.6 0.2 2.4 0.5 2.3 -1.7 -1.4 -1.6 -1.8 -0.5
Bilateral oophorectomy (both ovaries removed) 0.2 0.3 0.8 0.3 0.0 -0.9 -0.1 0.2 -0.9 -0.7 -0.5 0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.6 -1.0 -1.2 -1.1 -1.3 -0.2 -0.1 0.5 0.5 -0.4
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 3.5 -0.6 -1.8 -1.6 -1.9 0.4 0.3 0.3 0.3 -0.3
Qualifications: CSEs or equivalent 1.0 1.3 3.0 1.7 1.3 0.7 1.2 -0.5 -0.9 -1.3 -1.4 0.1
Serious illness, injury or assault to yourself 1.7 2.1 4.0 0.4 1.8 -0.0 1.6 -1.4 -1.6 -2.0 -1.8 -1.0
High blood pressure 1.1 3.0 6.1 2.3 2.4 -1.5 2.5 -2.2 0.4 -1.2 -1.2 -0.1
Hayfever, allergic rhinitis or eczema 0.3 0.6 1.4 -1.2 -1.0 -0.6 -1.1 0.7 1.0 0.1 -0.1 0.2
Multivitamins +/- minerals 0.2 0.3 0.7 0.4 0.7 0.3 0.8 -0.7 -0.9 -0.3 -0.1 0.2
Stomach or abdominal pain in last month 1.3 1.6 4.1 0.2 1.7 -2.0 1.6 -1.2 -1.8 -0.5 -0.3 0.6
Supplements: Glucosamine 3.0 4.0 7.8 2.3 2.6 0.3 2.8 -1.7 -2.3 -1.8 -2.0 0.4
Diverticular disease/diverticulitis (self-reported) 1.7 2.0 4.2 -2.0 -1.6 -0.1 -1.5 0.9 0.2 1.9 1.9 -0.6
Medication: Atenolol 1.1 1.4 4.7 -0.4 0.0 -2.2 0.1 -1.6 1.7 -0.7 -0.4 1.1
Medication: Levothyroxine sodium 0.3 0.5 2.9 -0.7 -0.1 -0.2 -0.1 -0.6 0.3 -0.3 -0.4 -1.7
Sitting height 0.5 3.4 8.9 0.3 -3.0 -0.4 -2.8 1.6 1.6 2.0 2.0 -0.8
Chronic bronchitis/emphysema (father) 1.2 1.4 3.4 0.1 -0.7 -1.7 -0.8 1.0 0.4 1.8 1.8 0.8
High blood pressure (mother) 2.9 4.0 12.4 1.0 1.1 -3.5 1.0 -2.8 1.3 -2.4 -2.2 -1.0
Body mass index (BMI) 0.6 2.7 6.1 -1.3 -2.3 -0.1 -2.4 2.5 0.5 1.3 1.2 1.5
Impedance of leg (left) 0.7 3.6 10.5 1.0 3.2 -0.1 3.2 -1.9 -1.5 -1.5 -1.3 -0.9
Leg predicted mass (left) 1.1 5.7 16.7 -2.1 -4.1 -1.0 -4.1 2.1 1.7 1.8 1.7 0.1
Trunk fat mass 0.6 2.6 5.9 -1.5 -2.2 -0.4 -2.2 2.4 0.6 1.4 1.2 1.4
Waist circumference 0.5 2.0 5.9 -0.9 -1.7 -0.2 -1.8 2.4 0.8 1.0 0.8 1.7
Number of incorrect matches in round 0.7 1.1 3.4 0.2 0.9 -0.2 0.9 -1.8 -1.8 -1.1 -1.0 -0.2
Past tobacco smoking 0.5 1.0 6.2 2.5 0.7 0.6 0.8 -0.0 -0.8 -0.3 -0.2 -0.7
Alcohol usually taken with meals 0.7 1.2 2.5 -0.0 -1.4 -0.4 -1.6 1.5 0.6 0.9 0.9 1.1
Nervous feelings 0.2 0.3 0.9 -0.3 -0.3 0.7 -0.2 -0.1 -0.4 0.9 1.0 -0.4
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 2.0 0.3 0.4 1.4 0.4 -1.1 0.2 -0.5 -0.3 -0.2
Hearing difficulty/problems with background noise 0.6 1.0 2.7 -1.6 -0.5 -1.5 -0.7 -0.0 1.4 -0.6 -0.5 -1.0
Hair/balding pattern: Pattern 2 3.4 4.3 7.5 -0.6 -2.7 2.1 -2.6 2.4 -1.1 1.8 2.0 2.2
Had menopause 0.2 0.3 1.3 0.9 -0.0 -1.2 -0.0 0.0 0.6 -0.3 -0.4 -0.1
Had other major operations 0.3 0.4 1.9 1.4 -0.4 0.7 -0.7 0.2 -0.3 0.4 0.2 0.0
Forced vital capacity (FVC) 0.5 2.1 7.8 0.7 0.6 -2.0 0.6 -2.8 -0.9 -1.1 -1.1 -1.6
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.3 -0.5 -1.1 -0.8 -1.1 -0.4 0.2 0.1 0.1 -1.1
Ever unenthusiastic/disinterested for a whole week 3.1 3.7 6.2 1.6 2.4 -1.7 2.3 -2.5 0.0 -2.2 -2.4 0.1
Qualifications: None of the above 0.8 1.6 4.7 0.9 2.2 0.5 2.0 -0.4 -0.8 -1.1 -1.3 1.0
Financial difficulties in last 2 years 0.5 0.6 2.0 0.3 -0.3 0.2 -0.3 1.1 -0.3 1.4 1.4 0.1
Mouth/teeth dental problems 1.2 1.9 4.5 1.5 1.2 0.4 1.2 -1.4 1.2 -1.5 -1.3 -2.1
Heart attack 0.7 0.9 2.9 1.2 0.8 -1.7 0.9 -0.5 1.2 0.5 0.6 0.2
Allergy 0.4 0.9 1.9 1.3 1.2 1.0 1.2 -0.2 -1.4 -0.3 -0.2 -0.9
Pain all over the body in last month 0.2 0.3 0.8 0.3 -0.3 -0.3 -0.3 -0.9 -0.8 -0.5 -0.3 0.4
Diabetes (self-reported) 2.1 3.3 7.2 -1.7 -2.7 0.6 -2.5 1.4 -1.0 2.1 2.2 -0.9
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.9 -1.4 -0.3 1.1 -0.2 -0.4 -0.9 -0.2 -0.1 0.5
Medication: Ramipril 1.1 1.4 4.0 1.3 0.2 2.0 0.1 1.7 1.8 0.7 0.6 0.3
Medication: Simvastatin 1.1 1.6 3.5 -1.0 -1.8 -1.3 -1.9 0.9 0.1 0.5 0.7 1.7
Fluid intelligence score 1.0 2.1 5.9 -1.1 -2.1 -1.2 -1.9 0.6 2.4 0.9 0.8 0.8
Illnesses of siblings 0.7 1.0 2.7 1.6 -0.6 1.0 -0.4 1.2 -0.3 1.3 1.1 0.3
Neuroticism score 0.5 1.1 2.7 -0.3 -1.2 -0.6 -1.2 0.5 1.6 1.4 1.3 -0.3
Weight 0.8 4.0 10.6 -1.7 -3.3 -0.8 -3.3 2.4 0.5 1.7 1.5 0.7
Impedance of arm (right) 1.3 6.1 16.3 2.3 4.0 0.8 4.0 -2.1 0.6 -2.5 -2.5 -0.3
Arm fat percentage (right) 0.3 1.4 5.3 -0.3 -0.9 0.9 -1.0 2.3 0.8 0.7 0.3 1.8
Trunk fat-free mass 1.1 6.6 19.4 -2.2 -4.4 -1.2 -4.4 1.9 0.6 2.3 2.2 -0.1
Hip circumference 0.9 3.9 8.8 -1.1 -2.9 0.2 -3.0 2.8 0.5 1.8 1.8 1.2
Time employed in main current job 0.9 1.0 3.3 -1.8 -1.1 -0.5 -1.0 -0.2 -0.8 1.1 1.3 -0.5
Alcohol intake versus 10 years previously 0.6 0.9 2.8 -0.6 -0.8 1.7 -0.7 1.5 -0.9 0.7 0.4 -0.0
Father’s age at death 1.5 2.0 5.2 -0.7 -2.3 0.4 -2.2 2.0 -0.7 0.8 1.3 0.4
Worrier / anxious feelings 0.9 1.7 3.5 -1.4 -1.5 0.2 -1.5 0.0 1.5 1.5 1.9 -0.9
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 0.9 0.2 0.3 0.5 0.4 -0.4 -0.9 0.1 0.2 0.6
Falls in the last year 0.2 0.3 0.7 -0.2 0.5 -0.2 0.6 -0.6 -0.5 -0.7 -0.7 -0.8
Hair/balding pattern: Pattern 3 0.8 1.2 5.3 -0.3 1.1 -2.3 0.9 0.1 0.7 0.2 0.2 -1.8
Number of live births 0.1 0.1 1.0 1.0 0.2 -0.4 0.2 0.0 0.2 -0.1 0.1 -0.1
Forced expiratory volume in 1-second (FEV1) 0.6 2.0 7.7 1.0 0.5 -2.2 0.6 -2.8 -0.9 -0.8 -0.8 -1.4
Pulse rate 0.2 0.3 1.3 1.1 0.2 -0.2 0.2 -0.3 -1.0 -0.5 -0.4 -0.3
Happiness 0.7 0.8 1.9 0.5 1.1 1.3 1.1 -1.4 0.5 -0.7 -0.6 -0.1
Noisy workplace 1.6 1.9 4.7 -0.3 -1.0 2.2 -1.1 1.8 -2.0 1.4 1.1 -0.1
Qualifications: A levels/AS levels or equivalent 1.8 4.0 8.3 -1.4 -2.9 -0.8 -2.9 1.5 1.9 2.2 2.0 -1.5
Serious illness, injury or assault of a close relative in last 2 years 2.1 2.4 5.3 -1.1 0.4 -1.2 0.3 -2.0 0.2 -2.2 -2.1 -2.3
Mouth/teeth dental problems: Dentures 0.6 1.0 6.1 -2.5 -0.5 0.3 -0.5 -0.1 -1.0 -0.0 -0.2 1.2
Asthma 1.4 2.8 8.2 -1.6 -1.6 0.8 -1.6 1.4 2.1 1.1 1.0 2.9
Medication: Ibuprofen (e.g. Nurofen) 2.6 3.3 7.5 0.6 2.6 0.8 2.4 -1.3 0.9 -2.5 -2.7 -0.0
Medication: Cholesterol lowering 0.7 1.0 4.5 -1.0 -0.8 -1.4 -0.9 0.1 2.1 -0.3 0.0 0.5
Depression (self-reported) 1.3 1.5 5.2 -0.1 -0.5 2.3 -0.4 1.2 -1.0 1.8 1.5 0.6
Medication: Lansoprazole 1.0 1.1 3.8 -1.7 -0.8 0.9 -0.9 -0.1 -1.9 -0.3 -0.4 -0.9
Prospective memory result 1.0 1.2 3.7 -0.5 1.9 1.0 1.6 -0.9 -1.6 0.1 -0.0 0.3
Lung cancer (father) 0.7 0.8 4.6 0.5 0.8 0.7 0.9 -0.6 -2.1 0.1 -0.0 -0.3
Illnesses of mother 0.8 0.9 2.9 1.0 -0.1 1.3 -0.2 1.7 -0.4 1.2 1.0 0.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.1 4.8 0.9 0.6 -1.3 0.7 -2.2 0.5 -0.9 -0.9 -0.8
Pulse wave Arterial Stiffness index 0.2 0.3 0.8 -0.4 -0.3 -0.8 -0.2 0.9 0.1 0.3 0.5 0.6
Impedance of arm (left) 1.2 5.6 14.1 2.1 3.7 0.3 3.8 -2.4 0.2 -2.4 -2.5 0.1
Arm fat mass (right) 0.7 2.9 6.3 -1.3 -2.4 -0.3 -2.5 2.4 1.0 1.3 1.1 1.6
Trunk predicted mass 1.2 6.8 20.0 -2.3 -4.5 -1.2 -4.5 2.0 0.6 2.3 2.2 -0.1
Standing height 0.2 1.6 4.3 -0.7 -2.1 -1.6 -1.9 0.0 0.3 0.8 0.7 -1.5
Length of working week for main job 1.7 1.9 5.1 -0.2 0.9 -1.9 0.8 -2.3 1.0 -1.0 -1.1 -1.9
Exposure to tobacco smoke at home 0.9 1.0 3.6 -0.6 -1.0 0.7 -1.1 0.8 -1.9 0.7 0.9 0.8
Breastfed as a baby 0.5 0.6 1.4 -0.7 -1.1 -0.1 -1.2 0.6 0.1 0.6 0.5 1.1
Tense / ‘highly strung’ 0.2 0.4 1.3 1.2 0.5 0.5 0.5 -0.1 1.1 0.1 -0.2 -0.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.9 1.3 2.5 -0.5 -1.0 1.5 -0.8 1.5 -0.8 1.6 1.3 -0.6
Hair/balding pattern: Pattern 4 0.9 2.1 4.5 1.7 2.0 2.1 2.0 0.1 -1.2 -0.8 -1.0 0.1
Birth weight of first child 0.4 0.7 2.3 1.1 0.4 -0.1 0.5 -0.3 0.2 -1.3 -1.5 -0.7
Peak expiratory flow (PEF) 0.2 0.5 2.6 1.1 0.4 -0.5 0.5 -1.6 -0.5 -0.3 -0.4 -0.0
Pulse wave reflection index 0.1 0.1 0.3 0.0 0.5 -0.4 0.4 -0.3 0.4 -0.2 -0.1 0.5
Ever highly irritable/argumentative for 2 days 0.6 0.7 1.7 -0.2 0.8 -0.9 0.9 -1.3 0.5 -1.1 -1.0 -0.6
Loud music exposure frequency 0.9 1.0 2.7 -0.4 0.5 -0.6 0.6 -1.2 1.6 -1.0 -1.0 -1.4
Qualifications: O levels/GCSEs or equivalent 1.8 2.9 8.0 -1.3 -1.8 -2.8 -1.9 0.2 2.7 0.9 1.0 -0.5
Mouth/teeth dental problems: Bleeding gums 0.6 0.8 2.6 0.2 -0.7 0.0 -0.7 1.6 -0.7 1.2 1.1 0.5
Blood clot in the leg (DVT) 0.8 1.1 4.8 0.4 0.2 -0.3 0.2 -1.3 -0.4 -1.1 -1.1 -2.2
Medication: Paracetamol 4.4 7.4 14.1 1.7 3.8 -2.0 3.7 -3.1 -0.4 -3.2 -3.4 -0.7
Headache pain in last month 2.0 3.5 7.3 0.5 1.7 -0.1 1.7 -2.3 -1.7 -2.6 -2.7 -1.8
Medication for cholesterol, blood pressure or diabetes 0.5 0.9 2.6 -0.3 -1.2 0.6 -1.0 0.6 -1.6 1.0 0.8 -0.6
Glaucoma (self-reported) 0.6 0.7 2.7 -0.9 -0.5 -1.6 -0.5 -1.0 -0.2 0.1 -0.2 -1.2
Gout (self-reported) 1.7 2.4 4.8 1.5 1.8 2.1 1.9 -1.0 -2.2 -0.9 -1.0 -0.1
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 2.8 0.1 0.6 -0.7 0.5 -0.6 -0.1 -0.4 -0.4 -1.7
Medication: Amlodipine 0.5 0.7 1.7 -1.3 -0.4 -0.8 -0.5 -0.8 0.3 -1.0 -0.9 -1.0
Medication: Ventolin 100micrograms inhaler 0.6 0.8 2.1 -1.5 -1.2 0.7 -1.2 0.6 0.6 0.7 0.5 0.6
Birth weight 0.4 0.8 1.9 1.4 0.8 1.2 0.7 0.3 0.0 -0.9 -0.8 -1.3
Chronic bronchitis/emphysema (mother) 0.6 0.8 4.5 0.3 0.2 0.5 0.2 -0.7 -2.1 -0.9 -0.6 0.1
High blood pressure (siblings) 0.4 0.6 1.5 -1.2 0.6 -1.0 0.4 -0.7 -0.1 -0.9 -0.8 0.2
Forced vital capacity (FVC), Best measure 0.4 1.4 5.2 0.7 0.8 -1.2 0.8 -2.3 0.4 -1.4 -1.3 -0.8
Body fat percentage 0.3 1.3 4.7 -1.1 -1.1 0.1 -1.2 2.2 0.3 0.8 0.6 1.6
Leg fat percentage (right) 0.4 1.4 3.6 -1.9 -1.2 -0.5 -1.3 1.6 -1.0 0.9 0.7 0.9
Arm fat-free mass (right) 1.7 8.8 24.7 -2.8 -5.0 -1.7 -5.0 2.3 0.9 2.5 2.6 0.1
Exposure to tobacco smoke outside home 0.6 0.8 2.7 -0.0 0.3 0.6 0.1 1.0 0.5 1.7 1.3 0.9
Comparative body size at age 10 0.4 1.2 2.2 0.2 0.8 -1.3 0.7 -1.5 1.3 -1.5 -1.3 -0.3
Number of full brothers 0.2 0.3 0.6 0.6 0.2 0.8 0.1 0.4 -0.6 0.6 0.1 0.7
Worry too long after embarrassment 0.9 1.5 4.0 -1.5 -0.9 -1.6 -0.9 -0.7 1.4 -0.3 -0.0 -2.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.7 -1.0 0.2 1.6 0.1 0.4 -0.2 -0.1 -0.4 0.6
Wheeze or whistling in the chest in last year 0.8 1.3 4.2 -0.1 -0.1 0.5 -0.2 2.1 1.3 1.5 1.1 1.6
Number of children fathered 0.7 0.8 2.2 -0.1 0.9 0.3 1.0 -1.1 -0.5 -1.5 -1.3 0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 3.0 -1.6 0.1 -0.5 -0.0 -1.7 -1.1 -0.4 -0.3 -0.7
Age at first live birth 0.7 1.2 3.8 0.5 0.4 0.6 0.4 -1.1 2.0 -1.4 -1.5 -1.0
Pulse wave peak to peak time 0.3 0.3 1.0 0.6 0.3 0.7 0.2 -1.0 0.1 -0.3 -0.5 -0.7
Health satisfaction 0.3 0.4 1.2 -0.9 0.2 0.9 0.2 0.7 0.1 0.3 0.5 1.1
Shortness of breath walking on level ground 0.5 0.6 2.3 -0.1 0.8 0.7 0.9 0.4 -1.0 0.1 0.3 1.5
Qualifications: College or University degree 0.4 1.3 4.9 -0.9 -0.5 -1.5 -0.6 -1.2 0.3 -0.9 -0.7 -2.2
Eye problems/disorders: None of the above 2.3 2.6 6.5 1.7 1.9 2.5 1.9 0.3 0.1 -1.3 -1.6 -1.6
Mouth/teeth dental problems: Loose teeth 1.1 1.3 4.8 -0.7 -0.7 0.3 -0.7 0.5 -2.2 1.1 1.2 1.6
Emphysema/chronic bronchitis 1.3 1.5 5.1 0.5 -0.6 1.8 -0.6 0.7 2.3 0.0 -0.1 1.9
Medication for pain relief, constipation, heartburn 1.9 3.3 8.1 -0.9 -2.9 0.8 -2.6 1.4 0.4 2.2 2.4 0.6
Neck or shoulder pain in last month 1.6 2.3 5.0 0.6 2.2 0.7 2.2 -1.1 1.0 -1.9 -2.1 -0.6
Medication: Blood pressure 0.8 1.4 3.3 1.1 1.8 -0.6 1.7 -1.0 1.8 -0.8 -0.4 0.1
Angina (self-reported) 0.6 0.8 3.7 -0.5 -0.1 -0.4 -0.2 -0.2 1.9 -0.7 -0.8 1.4
Migraine (self-reported) 2.2 2.8 6.2 1.6 1.9 -0.2 2.1 -1.7 0.5 -1.6 -1.5 -2.5
Medication: Ibuprofen 1.7 2.1 4.8 0.6 2.2 0.6 2.0 -0.4 0.5 -1.9 -2.2 -0.3
Medication: Allopurinol 0.5 0.6 1.7 1.0 0.3 1.2 0.4 0.1 -1.3 0.0 0.1 1.1
Medication: Omeprazole 0.5 0.6 1.7 -0.6 -0.0 -0.3 0.0 0.6 -1.1 1.3 1.2 -0.5
Medication: Seretide 50 evohaler 0.7 0.8 2.2 -1.5 -1.1 -0.7 -1.1 -0.0 1.3 -0.1 0.0 0.6
Mean time to correctly identify matches 4.1 7.9 13.8 -2.3 -2.9 1.0 -3.0 3.7 -1.5 3.7 3.6 2.2
Heart disease (mother) 1.3 1.6 3.2 0.0 1.8 -1.0 1.7 -1.3 -0.7 -0.9 -0.9 -1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 0.6 0.4 -0.1 0.4 0.1 -0.3 0.7 -0.7 -0.8 -0.6
Whole body fat mass 0.6 2.4 5.1 -1.5 -2.1 -0.4 -2.2 2.3 0.3 1.3 1.1 1.3
Leg fat mass (right) 0.7 2.6 5.2 -2.0 -2.2 -0.7 -2.3 2.1 -0.1 1.4 1.3 0.8
Arm predicted mass (right) 1.6 8.4 24.1 -2.8 -4.9 -1.9 -4.9 2.2 0.8 2.3 2.3 0.1
Pulse rate, automated reading 1.8 5.9 12.7 3.6 3.6 -1.2 3.5 -1.9 -0.9 -2.3 -2.2 -0.3
Alcohol intake frequency. 0.2 0.4 2.6 0.1 -0.4 0.0 -0.3 -0.4 -0.5 -0.5 -0.5 1.6
Comparative height size at age 10 0.6 3.4 6.8 -0.3 -2.6 -0.5 -2.6 1.6 0.6 2.4 2.5 1.5
Number of full sisters 1.4 1.7 2.9 -1.4 -1.4 1.4 -1.4 1.0 -1.1 1.1 1.0 1.7
Suffer from ‘nerves’ 0.7 1.0 2.9 0.6 0.9 1.7 0.8 0.7 -1.7 0.9 0.8 -0.2
Overall health rating 0.3 0.6 2.5 -0.5 1.0 0.1 0.9 -0.1 -0.6 0.4 0.2 1.6
Chest pain or discomfort 0.4 0.6 1.7 0.0 -0.9 0.8 -0.8 1.0 1.3 0.6 0.1 0.2
Had major operations 1.0 1.2 4.0 -0.6 0.7 -2.0 0.7 -1.4 -1.5 -0.5 -0.3 0.9
Age at last live birth 0.8 1.1 6.1 0.7 0.3 0.3 0.4 -0.4 2.5 -1.1 -1.1 0.4
Family relationship satisfaction 4.3 5.3 8.3 2.9 2.6 0.8 2.6 -2.6 1.6 -2.7 -2.9 -1.0
Leg pain on walking 0.3 0.4 1.4 -0.1 0.7 -0.3 0.6 0.8 -0.2 0.3 0.5 1.2
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 1.5 0.9 0.5 1.2 0.6 -0.5 0.3 -0.8 -0.7 0.2
Commuting to job workplace: Car/motor vehicle 1.3 1.5 2.6 0.0 1.4 1.3 1.4 -1.4 0.4 -1.4 -1.6 -1.2
Illness, injury, bereavement, stress in last 2 years 2.1 2.5 11.3 -0.7 -1.7 -0.7 -1.5 1.3 3.4 1.0 0.9 1.4
Medication: Aspirin 0.1 0.1 0.2 -0.1 -0.2 -0.3 -0.2 -0.2 0.1 -0.3 -0.3 0.5
Supplements: Vitamin C 0.2 0.3 1.2 0.1 0.2 -0.1 -0.0 1.1 -1.0 0.3 0.1 -0.4
Knee pain experienced in last month 0.7 1.1 2.5 0.5 1.3 -1.6 1.2 -1.1 0.5 -0.8 -0.8 1.4
Hypertension (Self-reported) 0.7 1.8 3.4 1.8 1.8 -1.6 1.8 -1.7 0.1 -0.7 -0.7 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 3.0 3.5 5.4 -1.7 -2.3 0.4 -2.2 2.0 -1.9 2.3 2.3 -0.0
Illnesses of father: Heart disease 0.5 0.7 1.5 1.2 1.2 0.2 1.0 -0.2 0.6 -0.7 -0.7 -0.9
Illnesses of siblings: Diabetes 1.1 1.3 5.8 -2.4 -1.5 0.8 -1.4 0.3 -0.0 0.5 0.4 -0.8
Smoking status: Previous 0.9 1.3 6.3 -2.5 -1.1 -0.7 -1.2 -0.5 0.9 -0.4 -0.5 1.1
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.3 0.9 -0.1 -0.3 0.3 -0.3 0.9 0.9 0.4 0.3 -0.8
Whole body fat-free mass 1.2 6.6 19.5 -2.2 -4.4 -1.2 -4.4 2.1 1.1 2.2 2.1 -0.0
Leg fat-free mass (right) 1.2 6.5 18.3 -1.8 -4.3 -0.8 -4.3 2.4 1.8 2.1 2.1 -0.1
Arm fat percentage (left) 0.4 1.6 5.0 -0.6 -1.1 0.4 -1.2 2.2 0.7 0.9 0.5 2.1
Average weekly red wine intake 0.4 0.6 1.7 -0.9 -0.5 -0.4 -0.6 0.9 -0.0 1.3 1.3 0.2
Handedness (chirality/laterality): Left-handed 1.4 1.6 3.1 1.4 1.8 1.2 1.7 -1.4 0.1 -0.8 -1.1 -1.2
Mood swings 0.4 0.7 1.4 -0.8 -1.2 0.8 -1.1 0.3 -0.4 0.9 1.0 -0.6
Loneliness, isolation 0.2 0.3 1.1 0.9 0.5 -0.1 0.4 -1.1 0.3 0.1 -0.2 0.4
Long-standing illness, disability or infirmity 0.5 0.7 2.1 -0.7 1.0 1.4 0.9 -0.5 -1.1 0.2 0.1 1.0
Ever had bowel cancer screening 0.4 0.5 1.8 -0.5 -0.4 -1.3 -0.4 0.8 -0.6 0.7 0.7 -0.5
Diabetes diagnosed by doctor 1.3 2.1 5.7 -1.9 -2.4 0.3 -2.3 0.9 -0.0 1.1 1.3 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 1.9 2.0 7.6 1.2 0.7 2.8 0.7 1.4 -1.0 1.2 0.9 1.8
Friendships satisfaction 1.3 1.6 2.5 1.6 1.2 0.5 1.3 -1.1 1.2 -1.4 -1.3 1.5
Qualifications: nursing, teaching 1.8 2.8 6.4 -1.9 -2.5 -0.2 -2.5 0.7 1.4 1.2 1.1 -1.9
Commuting to job workplace: Walk 1.3 1.4 3.0 1.6 -0.6 -1.1 -0.7 1.4 -0.4 1.7 1.7 0.1
Eye problems/disorders: Cataract 1.8 2.1 6.3 -0.9 -1.3 -2.2 -1.6 0.2 0.7 0.8 1.2 2.5
Mouth/teeth dental problems: Mouth ulcers 0.9 1.5 3.2 -1.1 -1.0 -0.4 -1.2 1.8 -0.2 1.4 1.3 1.6
Medication for cholesterol 0.2 0.3 2.2 -0.1 -0.1 1.5 -0.1 0.2 0.4 -0.4 -0.3 -0.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 3.4 -0.4 -0.1 -1.2 -0.1 -0.0 -0.0 -0.5 -0.3 1.8
Back pain experienced in last month 0.5 0.7 3.2 -0.3 -0.2 1.0 -0.2 1.1 0.8 0.1 -0.1 1.8
Mineral and other dietary supplements 2.0 2.7 5.5 -1.2 -2.3 -1.3 -2.3 1.4 1.8 1.5 1.4 -1.0
Breast cancer (self-reported) 0.7 0.8 2.4 0.1 1.1 1.6 1.1 0.8 -1.1 -0.4 -0.5 0.7
Asthma (self-reported) 1.4 2.7 8.7 -1.8 -1.5 0.9 -1.6 1.1 2.0 0.8 0.8 3.0
Osteoporosis (self-reported) 0.1 0.1 0.3 0.3 0.3 -0.0 0.3 0.3 -0.5 0.3 0.4 0.4
Osteoarthritis (self-reported) 1.3 1.6 7.5 0.9 1.6 0.2 1.7 -0.0 -2.7 -0.3 -0.1 0.7
Medication: Aspirin 0.2 0.2 0.5 -0.6 -0.7 -0.2 -0.7 -0.0 0.2 -0.2 -0.1 0.7
Medication: Gliclazide 3.2 3.6 8.2 -1.7 -2.9 -0.5 -2.8 0.7 1.8 1.6 1.8 1.8
Illnesses of father: None of the above (group 1) 0.3 0.4 1.5 0.4 0.1 0.8 0.2 0.0 -1.2 0.3 0.4 1.0
Smoking status: Current 1.8 2.9 6.9 1.7 2.6 2.1 2.5 -0.2 -0.1 -1.4 -1.5 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 3.1 0.6 0.4 -1.0 0.5 -1.8 0.9 -0.8 -0.7 0.6
Whole body water mass 1.2 7.1 20.7 -2.2 -4.5 -1.2 -4.5 2.2 1.2 2.2 2.1 -0.2
Leg predicted mass (right) 1.2 6.4 18.0 -1.8 -4.2 -0.8 -4.2 2.4 1.8 2.2 2.1 -0.1
Arm fat mass (left) 0.7 2.9 6.3 -1.3 -2.5 -0.4 -2.5 2.4 0.8 1.4 1.1 1.5
Number of self-reported non-cancer illnesses 0.5 0.9 2.9 0.6 1.6 1.0 1.7 -0.6 -0.6 -0.4 -0.4 -0.0
Average weekly champagne plus white wine intake 0.2 0.3 1.0 0.1 0.6 -0.8 0.5 -0.5 0.6 0.2 0.2 -1.0
Miserableness 0.2 0.3 0.5 0.7 -0.3 0.2 -0.3 0.7 -0.4 0.6 0.6 0.6
Guilty feelings 3.6 5.4 11.1 -2.2 -3.2 0.3 -3.3 2.2 -0.2 2.7 2.9 1.3
Wears glasses or contact lenses 0.5 0.6 1.5 -1.0 -1.0 -0.6 -1.1 0.7 1.2 0.0 0.1 -0.1
Ever taken oral contraceptive pill 0.4 0.5 1.7 -0.7 0.2 0.8 0.1 0.5 -0.5 0.8 0.5 -1.3
Hearing aid user 0.9 1.0 3.5 -1.9 -0.4 -0.4 -0.5 -0.9 1.2 -0.8 -0.5 1.3
Mother’s age at death 0.3 0.3 0.7 -0.2 -0.8 -0.0 -0.8 0.4 -0.5 0.8 0.7 0.5
Financial situation satisfaction 0.2 0.2 0.7 -0.0 0.3 -0.6 0.3 0.1 0.8 -0.3 -0.4 -0.7
Tinnitus: Yes, now most or all of the time 2.2 2.6 9.8 0.8 -0.4 -3.1 -0.3 -1.5 2.3 -1.6 -1.3 -0.7
Commuting to job workplace: Public transport 1.3 1.5 6.1 0.1 -1.2 -2.5 -1.3 0.6 -1.0 1.0 1.2 0.7
Eye problems/disorders: Glaucoma 0.9 1.0 3.1 -0.9 -0.4 -1.2 -0.4 -1.7 -0.3 -0.5 -0.5 -1.8
Medication: Blood pressure 0.3 0.6 1.4 -0.0 -1.0 -0.8 -1.0 0.3 0.2 1.2 0.8 0.8
Pain type(s) experienced in last month: Hip pain 0.5 0.6 3.0 0.0 1.7 0.1 1.6 -0.0 -0.1 0.0 -0.3 0.4
Supplements: Fish oil (including cod liver oil) 1.4 1.9 7.0 -0.2 1.3 1.8 1.2 -1.0 -1.3 -0.6 -0.4 2.6
High cholesterol (Self-reported) 0.5 0.8 5.0 -0.5 0.0 -2.2 -0.0 -0.8 -0.6 -0.8 -0.7 0.4
Medication: Bendroflumethiazide 0.2 0.3 0.7 -0.7 -0.7 -0.5 -0.5 -0.9 0.4 -0.0 -0.2 -0.2
Medication: Paracetamol 3.4 5.3 10.3 1.5 3.2 -0.9 3.2 -2.6 -2.0 -2.5 -2.6 -0.3
Medication: Lisinopril 0.7 0.9 1.6 -1.3 -0.2 -0.9 -0.3 -0.5 -1.2 1.0 1.1 1.2
Medication: Atorvastatin 0.9 1.2 2.5 0.5 0.5 -0.5 0.6 -1.2 1.6 -1.2 -1.3 -1.4
Illnesses of father: High blood pressure 0.5 0.6 1.9 0.6 0.8 -1.4 0.8 -0.4 0.7 -0.2 -0.5 -0.9
Alcohol drinker status: Never 0.7 0.9 3.5 -0.9 -1.1 -0.9 -0.9 -0.6 1.9 0.2 0.4 0.7
Ever smoked 0.3 0.6 2.5 -1.6 -0.1 -1.0 -0.2 -0.4 1.2 -0.2 -0.2 -0.7
Basal metabolic rate 1.1 6.3 18.4 -2.2 -4.3 -1.1 -4.3 2.2 1.1 2.1 2.0 -0.0
Leg fat percentage (left) 0.5 1.8 4.2 -1.7 -1.6 -0.4 -1.6 2.0 -0.9 1.3 1.2 0.8
Arm fat-free mass (left) 1.5 7.4 21.2 -2.3 -4.6 -1.5 -4.6 2.4 1.1 2.2 2.2 -0.1
Number of operations (self-reported) 0.3 0.5 1.1 -0.6 -0.0 -0.7 -0.2 -0.9 -0.6 -1.1 -1.0 0.1
Average weekly beer plus cider intake 1.2 1.7 3.0 -0.0 1.6 -0.7 1.7 -1.7 0.4 -1.7 -1.6 0.7
Irritability 0.2 0.4 1.2 -0.3 -0.9 -0.0 -0.9 0.4 0.4 0.6 0.3 -1.1
Risk taking 0.8 1.2 7.4 -0.9 -0.1 1.5 -0.1 0.5 0.0 0.0 -0.2 -2.7
Ever had prostate specific antigen (PSA) test 1.2 1.3 2.8 -1.7 -1.5 -1.3 -1.5 0.7 1.0 0.2 0.2 -1.2
Fractured/broken bones in last 5 years 0.5 0.6 1.8 -0.4 -0.6 0.8 -0.5 1.3 -0.9 0.6 0.7 0.7
Age started oral contraceptive pill 1.1 1.4 3.3 -1.2 -1.0 -0.9 -1.1 1.1 -0.6 1.7 1.8 -0.2
Diastolic blood pressure, automated reading 1.1 3.4 7.1 1.4 2.7 -1.2 2.5 -2.6 0.8 -1.8 -1.6 0.7
Ever depressed for a whole week 0.6 0.7 3.1 -0.1 0.1 -1.8 -0.1 -0.5 1.5 -0.4 -0.6 -0.6
Unable to work because of sickness or disability 0.3 0.3 2.0 -0.8 -0.3 -0.2 -0.3 -0.4 0.0 0.1 0.0 1.4
Commuting to job workplace: Cycle 0.3 0.4 1.6 -0.0 -0.1 -1.2 0.0 -0.7 0.0 -0.0 -0.1 -1.3
Myopia 1.1 1.6 7.1 0.1 -0.7 -1.8 -0.7 1.4 0.5 0.7 0.5 2.7
Vascular/heart problems diagnosed by doctor 1.0 2.6 6.6 -2.6 -2.1 1.4 -2.1 1.8 -1.0 0.8 0.8 -0.3
Cholesterol lowering medication 0.6 1.0 5.5 -0.9 -0.6 -2.3 -0.6 -1.0 -0.5 -0.3 -0.3 0.2
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 1.8 -0.7 -0.1 -0.3 -0.1 0.5 -1.4 1.3 1.3 -0.8
Pain experienced in last month 0.3 0.4 1.9 -0.2 -0.8 0.1 -0.6 0.4 -0.2 0.5 0.7 -1.4
Supplements: Calcium 0.5 0.6 1.6 -1.2 0.1 0.6 0.1 0.4 -0.2 -1.0 -1.0 1.0
Basal cell carcinoma (self-reported) 0.7 0.8 2.1 0.9 0.6 0.2 0.7 -0.8 0.4 -1.1 -1.3 -1.5
Heart attack/myocardial infarction (self-reported) 0.8 1.1 3.3 1.4 0.9 -1.8 1.0 -0.7 1.4 0.2 0.5 0.3
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 5.0 0.2 0.1 -0.8 0.0 -1.1 -0.2 -0.9 -1.0 -2.2
Heart disease (siblings) 0.9 1.1 2.6 -0.2 1.5 -0.5 1.3 -0.5 0.2 -1.6 -1.5 0.2
Alcohol drinker status: Previous 0.9 1.1 2.7 -0.3 1.0 -0.3 0.8 -1.4 -0.7 -1.6 -1.3 0.8
Pack years of smoking 0.2 0.2 0.7 -0.5 -0.2 -0.2 -0.3 0.7 0.0 0.7 0.8 0.2
Impedance of whole body 1.1 5.4 14.8 2.0 3.9 -0.1 3.9 -2.3 -0.4 -2.2 -2.2 -0.3
Leg fat mass (left) 0.8 3.0 6.2 -1.9 -2.4 -0.7 -2.5 2.4 0.0 1.6 1.4 0.8
Arm predicted mass (left) 1.5 7.5 22.0 -2.3 -4.7 -1.5 -4.7 2.4 0.9 2.1 2.1 0.1