Hub : Genes

TMEM66

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.2400	0.0580	5.0e-05	0.143	NA	0.133	NA	0.141	6.9e-11	NA	3.6e-10	NA	9.8e-11
2	GTEx	Skin Sun Exposed Lower leg	0.1210	0.0400	8.2e-04	0.120	NA	0.119	NA	0.107	4.3e-10	NA	4.4e-10	NA	3.7e-09
3	NTR	Blood	0.0163	0.0078	8.5e-03	0.018	0.003	0.018	0.018	0.020	1.6e-06	2.2e-02	1.3e-06	1.4e-06	3.6e-07
4	ROSMAP	Brain Pre-frontal Cortex	0.0994	0.0257	7.8e-09	0.099	0.083	0.078	0.087	0.087	1.1e-12	7.1e-11	2.9e-10	3.1e-11	3.0e-11
5	YFS	Blood	0.0287	0.0096	4.9e-05	0.001	0.013	0.006	0.013	0.000	1.6e-01	3.5e-05	3.1e-03	3.7e-05	2.5e-01
6	TCGA	Breast Invasive Carcinoma	0.0151	0.0088	9.2e-03	0.015	0.007	0.007	NA	0.013	4.1e-04	1.0e-02	1.2e-02	NA	1.0e-03
7	TCGA	Lung Adenocarcinoma	0.0470	0.0217	6.9e-05	0.049	0.030	0.023	NA	0.040	2.1e-06	1.8e-04	8.7e-04	NA	1.5e-05
8	TCGA	Pancreatic Adenocarcinoma	0.1400	0.0850	3.8e-03	0.008	0.002	-0.002	NA	-0.003	1.4e-01	2.5e-01	3.9e-01	NA	4.7e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	3.7	5.8	9.0	2.6	2.5	2.5	-2.1	2.1	2.6	3.0	1.7
Bipolar Disorder or Schizophrenia	0.1	0.2	0.3	0.3	0.4	0.3	-0.3	-0.5	0.5	0.3	0.5
Depressed Affect (Nagel 2018)	0.5	1.1	2.2	-1.1	-1.1	-1.2	0.7	-0.5	-1.1	-1.5	-0.7
Depression (Nagel 2018)	2.3	3.4	5.2	-2.0	-2.1	-2.3	1.4	-0.8	-2.0	-2.3	-1.5
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.0	0.5	0.6	0.6	-0.9	0.6	0.7	1.4	0.6
Neuroticism (Nagel 2018)	1.0	2.4	4.0	-1.6	-1.7	-1.9	1.1	-0.4	-1.6	-2.0	-1.5
Schizophrenia (2018)	1.3	2.7	5.1	-1.7	-1.6	-1.6	1.3	-2.3	-1.5	-2.0	-0.7
Schizophrenia vs Biploar Disorder	8.1	10.7	16.6	-3.6	-3.7	-3.5	2.3	-3.1	-3.7	-4.1	-1.7
Worry (Nagel 2018)	0.7	1.4	2.1	-1.4	-1.3	-1.4	0.7	-0.6	-1.3	-1.5	-1.0
Alzheimer’s Disease (in mother)	0.7	0.8	1.3	0.9	0.9	0.9	-0.8	1.1	1.1	1.1	0.1
Alzheimer’s Disease (in father)	0.2	0.2	0.6	0.4	0.1	0.2	0.1	-0.6	0.2	0.6	0.8
Alzheimer’s Disease (including proxy)	0.7	1.1	1.8	1.1	1.0	1.3	-0.9	0.5	1.1	1.3	0.8
Crohns Disease (2017)	1.8	3.9	6.8	2.3	2.6	2.5	-1.4	0.5	2.4	1.9	0.7
Irritable Bowel Disease (IBD)	0.9	2.2	3.9	1.5	1.9	2.0	-1.8	-0.3	1.6	1.2	0.9
Ulcerative Colitis (UC)	0.3	0.5	1.6	-0.0	0.3	0.4	-1.1	-1.3	-0.1	-0.2	0.9
Major Depression (MDD)	0.2	0.3	1.2	0.4	0.3	0.1	0.5	-1.1	0.5	0.6	-0.4
Reaction Time	0.8	1.4	2.9	-1.4	-1.2	-1.1	0.1	-1.7	-1.3	-1.4	-0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.3	0.6	0.9	0.7	-1.1	0.1	0.7	0.7	0.0
Breast Cancer	0.9	2.3	17.9	0.2	-0.2	0.1	0.1	4.2	0.1	0.0	0.5
Ovarian Cancer	0.6	0.8	3.0	0.4	0.8	0.7	-1.7	0.6	0.4	0.2	1.4
Prostate Cancer	3.3	4.7	7.7	2.8	2.6	2.3	-0.8	1.0	2.8	2.4	1.8
Age at First Birth	0.1	0.1	0.3	0.4	0.5	0.2	0.4	-0.1	0.5	0.5	-0.0
Bipolar Disorder (2011)	0.9	0.9	2.0	0.0	0.7	0.9	-1.0	1.1	0.7	0.9	1.4
Body Mass Index (BMI) (2010)	0.1	0.2	0.5	0.4	0.7	0.3	-0.5	0.6	0.3	0.4	-0.0
Coronary Artery Disease (CAD)	0.3	0.4	1.2	0.8	0.6	-0.1	-0.2	-0.1	0.8	1.1	0.6
Crohns Disease (2012)	0.7	1.2	1.8	1.3	1.3	1.3	-0.9	0.9	1.3	0.9	0.6
Mean Putamen Volume	0.6	0.7	3.2	-0.8	-0.5	-0.8	-0.3	1.8	-0.7	-0.5	0.3
Fasting Glucose	1.2	1.5	7.5	0.0	0.3	0.9	-1.6	0.9	-0.2	-0.1	2.7
HbA1C	5.0	5.5	7.6	2.2	2.2	2.8	-2.7	1.7	2.3	2.6	2.3
HDL Cholesterol	0.1	0.1	0.4	0.4	0.3	0.4	0.2	0.1	0.2	0.5	0.7
LDL Cholesterol	0.3	0.5	1.4	0.6	0.6	0.4	-0.4	1.2	0.7	0.5	-0.7
Lupus	0.2	0.3	0.8	0.4	0.7	0.5	-0.9	-0.7	0.5	0.5	-0.1
Neuroticism (2016)	0.6	0.9	1.6	-0.8	-0.8	-0.7	1.2	1.3	-0.9	-1.2	-0.6
Primary Biliary Cirrhosis	0.7	1.0	1.6	1.1	1.2	1.2	-0.9	0.8	1.1	1.2	0.6
Rheumatoid Arthritis	0.7	1.0	2.2	1.1	1.2	0.7	-0.1	-1.5	1.2	1.1	-0.1
Schizophrenia (2014)	1.5	3.2	5.7	-2.0	-1.7	-1.8	0.9	-2.4	-1.7	-2.3	-1.1
Triglycerides	0.1	0.1	0.3	-0.5	-0.3	-0.3	-0.3	0.1	-0.4	-0.5	-0.3
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.4	-0.2	0.1	0.0	-1.0	0.1	-0.3	-0.4	1.2
Ulcerative Colitis	0.3	0.4	0.6	-0.8	-0.6	-0.5	-0.4	-0.6	-0.8	-0.8	-0.2
Blood Eosinophil Count	0.2	1.9	2.5	1.6	1.4	1.5	-0.8	1.2	1.5	1.2	1.6
Blood Platelet Count	0.5	5.5	26.9	-0.9	-0.4	0.2	-2.3	5.2	-1.0	-0.6	3.1
Blood Red Count	0.2	1.6	9.9	0.8	0.4	0.6	0.9	3.1	0.8	0.7	0.2
Blood White Count	0.3	2.5	12.9	1.1	0.9	1.3	-0.5	3.6	1.0	1.0	1.3
Heel T-Score	0.1	0.5	1.7	0.1	-0.1	-0.1	-0.4	1.3	0.4	0.3	-1.3
BMI	0.0	0.2	0.7	0.4	0.4	0.2	0.1	0.2	0.2	0.3	0.9
Height	0.3	5.0	26.3	-0.3	-1.8	-0.9	2.6	5.1	-0.4	-0.2	-1.7
Waist Hip Ratio (WHR)	0.1	0.3	0.8	0.6	-0.0	0.6	0.3	0.9	0.7	0.7	0.1
Systolic Blood Pressure	0.5	2.6	7.1	1.5	1.6	1.9	-1.4	0.0	1.3	1.3	2.7
Smoking Status	2.5	5.9	9.8	-2.2	-2.4	-2.4	3.1	-2.1	-2.2	-2.6	-2.2
Allergy or Eczema	0.1	0.4	1.1	0.3	0.5	0.5	-1.0	0.7	0.2	0.1	0.9
Cardiovascular Disease	0.2	0.8	4.5	0.3	0.5	0.7	0.2	-2.1	0.2	0.4	1.0
Hypothyroidism (self reported)	0.5	1.2	6.5	-0.2	-0.4	-0.6	1.6	-2.5	-0.5	-0.2	0.1
Respiratory disease	0.1	0.1	0.4	0.2	0.3	0.0	0.4	-0.6	0.2	-0.2	-0.6
Type 2 Diabetes (T2D) (2018)	1.8	3.3	5.1	-1.9	-1.9	-2.0	1.8	-0.9	-1.9	-2.2	-1.6
Lung FEV1/FVC ratio	1.9	9.4	29.6	2.4	2.9	3.4	-5.4	1.1	2.6	2.1	2.8
Lung FVC	0.5	2.5	3.7	-1.9	-1.8	-1.8	1.4	-1.6	-1.9	-1.4	-0.5
Neuroticism	0.6	1.4	2.7	-1.3	-1.3	-1.4	0.9	0.0	-1.2	-1.6	-1.1
Chronotype (morning person)	0.1	0.2	0.5	-0.2	-0.5	-0.4	0.2	0.7	-0.3	-0.3	-0.3
Hair Pigment	0.0	0.2	1.0	0.6	0.3	0.4	0.3	0.4	0.3	0.4	1.0
Tanning	0.1	0.6	1.2	-1.1	-1.1	-1.0	-0.3	0.5	-0.9	-0.6	-0.3
Hand grip strength (left)	0.6	1.5	2.0	1.3	1.2	1.4	-1.2	1.1	1.3	1.2	1.0
Number of treatments/medications taken	1.1	2.0	3.6	-1.3	-1.3	-1.5	1.1	-1.9	-1.4	-1.5	-1.0
Average weekly spirits intake	0.1	0.2	1.0	-0.2	-0.1	0.0	0.0	0.5	0.2	0.3	-1.0
Sensitivity / hurt feelings	0.7	1.1	2.0	1.2	1.3	1.0	-1.0	1.4	1.2	0.8	0.1
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.4	-0.5	-0.2	-0.4	-0.4	0.2	-0.4	-0.6	-0.2
Hearing difficulty/problems: Yes	0.5	0.8	2.9	0.5	-0.1	0.1	1.5	1.7	0.5	0.6	-0.4
Relative age of first facial hair	0.1	0.3	1.2	-0.3	-0.3	-0.5	0.5	-0.6	-0.2	0.1	-1.1
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	3.4	1.6	1.5	1.2	-0.7	-0.4	1.5	1.9	0.4
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.1	0.0	-0.3	-0.4	1.2	-1.4	0.0	0.3	-1.4
Ever had hysterectomy (womb removed)	0.3	0.3	1.0	-0.1	-0.1	0.3	-1.0	-0.8	-0.0	0.2	1.0
Systolic blood pressure, automated reading	0.1	0.3	0.7	0.5	0.5	0.6	0.2	-0.1	0.5	0.6	0.8
Eye problems/disorders: Diabetes related eye disease	1.7	1.8	4.6	-1.6	-1.3	-1.6	0.5	-0.1	-1.7	-2.1	-0.2
Angina	0.6	0.8	1.9	-1.0	-0.5	-0.6	-0.6	-1.1	-0.8	-1.4	-0.7
Medication for hormone replacement therapy	0.7	0.8	2.4	-0.5	-0.7	-0.7	1.1	-1.0	-0.5	-0.0	-1.5
Vitamin and mineral supplements	3.8	5.2	9.2	2.9	2.9	2.6	-1.2	0.4	3.0	2.8	0.2
Supplements: Zinc	0.7	0.8	1.4	-1.0	-1.1	-0.9	0.5	0.2	-1.0	-1.2	0.8
Medication: Co-codamol	0.2	0.2	1.0	0.3	0.1	0.3	-0.1	0.6	0.1	0.5	1.0
Medication: Metformin	0.5	0.8	1.1	-0.8	-1.0	-1.1	0.9	-0.1	-0.9	-1.0	-0.7
Diabetes (father)	0.3	0.4	1.3	-0.8	-0.4	-0.4	-0.6	1.1	-0.7	-0.1	-0.0
Diabetes (mother)	0.2	0.3	1.3	0.3	0.0	0.0	0.9	-1.1	0.0	0.2	0.5
Severe depression (siblings)	1.3	1.5	2.9	1.4	1.5	1.3	-0.9	-0.1	1.3	1.7	0.6
Pack years adult smoking proportion	0.9	1.4	2.8	-0.9	-0.8	-1.0	1.5	-1.5	-0.9	-0.5	-1.7
Impedance of leg (right)	0.0	0.1	0.3	-0.1	-0.3	-0.3	0.6	-0.0	-0.1	-0.2	-0.5
Leg fat-free mass (left)	0.1	0.3	1.7	0.2	-0.1	0.1	0.1	1.3	0.0	0.3	0.8
Trunk fat percentage	0.2	0.6	1.1	0.9	1.1	0.6	0.0	0.7	1.0	0.9	-0.5
Hand grip strength (right)	0.6	1.7	2.7	1.6	1.5	1.4	-1.0	0.4	1.6	1.6	0.4
Townsend deprivation index at recruitment	1.3	1.9	3.2	-1.4	-1.4	-1.3	1.4	-1.2	-1.5	-1.8	-0.6
Current tobacco smoking	2.2	3.6	6.5	-1.8	-1.8	-1.9	2.5	-1.3	-1.8	-2.1	-1.6
Average weekly fortified wine intake	0.1	0.1	0.4	0.2	0.2	0.1	-0.3	-0.1	0.2	-0.1	-0.6
Maternal smoking around birth	0.2	0.4	1.3	-0.4	-0.7	-0.4	1.2	-0.4	-0.4	-0.2	-0.7
Fed-up feelings	0.1	0.2	0.6	0.1	-0.1	-0.2	0.8	0.5	-0.2	-0.3	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.9	2.5	4.2	-1.8	-1.7	-1.7	1.2	-1.5	-1.9	-2.0	-0.3
Relative age voice broke	0.1	0.1	0.7	0.1	0.1	-0.0	-0.2	0.8	0.0	0.1	-0.1
Taking other prescription medications	0.2	0.2	0.7	0.6	0.8	0.4	-0.1	-0.6	0.5	0.3	0.2
Age when periods started (menarche)	0.3	0.8	3.0	0.3	0.3	0.7	-1.5	-0.3	0.3	0.6	1.7
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	5.3	-0.8	-0.8	-0.5	-0.2	-2.3	-0.8	-0.5	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.7	0.2	0.0	0.1	-0.4	0.8	0.2	0.1	-0.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.8	0.3	0.3	0.4	-0.9	1.3	0.2	0.4	0.7
Qualifications: CSEs or equivalent	0.9	1.1	3.3	0.5	0.7	1.0	-1.5	0.3	0.5	1.1	1.8
Serious illness, injury or assault to yourself	0.9	1.1	6.3	0.5	0.6	0.6	-0.5	-2.5	0.4	0.4	0.9
High blood pressure	0.1	0.4	1.8	0.0	0.4	0.5	-0.8	-1.4	0.1	-0.1	0.3
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.4	0.6	0.7	0.6	-0.3	0.5	0.6	0.4	0.6
Multivitamins +/- minerals	3.5	4.5	8.0	-2.6	-2.6	-2.4	0.9	-0.3	-2.8	-2.8	0.2
Stomach or abdominal pain in last month	0.8	1.0	4.6	-0.1	-0.2	-0.4	0.6	-2.1	-0.1	-0.6	-1.5
Supplements: Glucosamine	1.2	1.6	2.7	-1.6	-1.5	-1.3	-0.3	1.0	-1.6	-1.5	-0.4
Diverticular disease/diverticulitis (self-reported)	2.9	3.4	5.8	2.4	2.2	2.2	-0.8	0.3	2.3	2.2	1.1
Medication: Atenolol	0.4	0.4	2.2	-0.5	-0.1	-0.5	-0.5	-0.5	-0.3	-0.5	-1.5
Medication: Levothyroxine sodium	0.1	0.2	0.5	-0.3	-0.3	-0.2	0.4	-0.7	-0.4	-0.5	0.6
Sitting height	0.1	0.9	6.2	0.3	-0.0	0.2	0.3	2.5	0.3	0.7	-0.1
Chronic bronchitis/emphysema (father)	1.1	1.3	3.8	1.2	1.1	0.9	0.4	-1.9	1.2	1.0	-0.7
High blood pressure (mother)	0.1	0.1	0.5	0.4	0.3	0.2	0.0	0.0	0.3	0.7	0.2
Body mass index (BMI)	0.1	0.3	0.5	0.6	0.7	0.6	-0.5	-0.0	0.6	0.7	0.6
Impedance of leg (left)	0.0	0.1	0.7	0.2	0.1	-0.0	0.6	-0.0	0.3	0.1	-0.8
Leg predicted mass (left)	0.1	0.3	1.4	0.2	-0.1	0.1	0.1	1.2	0.0	0.3	0.7
Trunk fat mass	0.1	0.3	0.8	0.6	0.6	0.3	0.2	0.9	0.7	0.7	-0.3
Waist circumference	0.0	0.1	0.5	0.1	-0.3	0.0	0.3	0.7	0.1	0.2	0.2
Number of incorrect matches in round	0.2	0.4	0.6	-0.5	-0.5	-0.6	0.6	-0.8	-0.4	-0.4	-0.7
Past tobacco smoking	1.2	2.2	3.2	1.5	1.5	1.4	-1.8	1.2	1.3	1.7	1.4
Alcohol usually taken with meals	0.0	0.0	0.1	-0.0	0.0	0.1	-0.0	0.4	0.1	0.1	-0.1
Nervous feelings	0.2	0.4	1.5	0.0	0.2	0.3	-0.6	-0.9	-0.0	-0.6	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	5.0	0.1	0.2	0.5	-1.2	1.2	-0.1	0.1	2.2
Hearing difficulty/problems with background noise	0.1	0.2	1.0	0.2	0.1	0.1	1.0	0.1	0.3	0.6	-0.5
Hair/balding pattern: Pattern 2	0.9	1.2	2.1	1.1	1.3	1.0	-0.8	0.8	1.3	1.4	0.8
Had menopause	0.5	0.6	2.3	-0.8	-0.7	-0.6	0.2	-1.5	-0.8	-0.6	-0.3
Had other major operations	0.1	0.1	0.3	-0.3	-0.1	-0.3	-0.6	-0.6	-0.3	0.0	-0.0
Forced vital capacity (FVC)	0.1	0.3	2.0	-0.1	-0.5	-0.5	1.4	-0.1	-0.3	0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	2.4	1.3	1.2	1.2	-0.7	1.6	1.4	1.4	0.1
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.6	-0.5	0.2	-0.1	-0.5	-0.5	-0.3	-0.2	0.7
Qualifications: None of the above	0.7	1.4	2.3	-1.1	-1.0	-1.4	1.4	0.0	-1.1	-1.4	-1.5
Financial difficulties in last 2 years	1.3	1.7	5.9	0.1	-0.2	-0.5	2.4	-1.7	-0.0	-0.4	-2.1
Mouth/teeth dental problems	0.9	1.4	2.9	1.0	1.0	1.2	-1.1	1.4	1.0	1.0	1.7
Heart attack	1.3	1.6	4.8	-1.5	-1.0	-1.0	-0.4	-1.1	-1.5	-2.2	0.5
Allergy	0.1	0.2	0.8	0.3	0.1	0.3	-0.2	0.9	0.3	0.5	0.3
Pain all over the body in last month	4.1	4.4	6.3	-2.2	-2.5	-2.5	2.2	-0.5	-2.4	-2.5	-1.4
Diabetes (self-reported)	0.2	0.3	0.7	-0.4	-0.4	-0.5	0.6	-0.1	-0.5	-0.8	-0.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	2.0	-1.1	-1.4	-1.2	0.8	0.6	-1.4	-1.3	-0.3
Medication: Ramipril	0.2	0.3	0.6	-0.5	-0.5	-0.5	0.4	-0.8	-0.6	-0.7	0.4
Medication: Simvastatin	1.9	2.8	4.3	-1.8	-1.6	-1.8	0.8	-2.0	-1.7	-2.1	-1.2
Fluid intelligence score	0.7	1.4	2.0	1.1	1.2	1.2	-1.4	1.0	1.0	1.0	1.3
Illnesses of siblings	0.5	0.7	4.9	0.2	0.1	0.5	-0.3	-0.1	0.1	0.3	2.2
Neuroticism score	0.3	0.6	1.3	-0.8	-0.8	-0.9	0.6	-0.5	-0.8	-1.1	-0.5
Weight	0.1	0.3	1.5	0.5	0.3	0.4	-0.1	1.2	0.4	0.6	0.4
Impedance of arm (right)	0.2	0.8	2.5	0.2	0.8	0.7	-1.2	1.6	0.3	0.1	1.1
Arm fat percentage (right)	0.1	0.5	0.9	0.7	1.0	0.7	-0.7	0.8	0.7	0.6	0.6
Trunk fat-free mass	0.1	0.6	2.2	-0.5	-1.1	-0.5	0.5	1.5	-0.7	-0.3	0.5
Hip circumference	0.1	0.3	1.4	0.4	0.3	0.3	-0.1	1.2	0.4	0.5	0.4
Time employed in main current job	1.1	1.2	3.9	0.7	1.2	1.2	-2.0	0.3	0.9	0.7	1.1
Alcohol intake versus 10 years previously	1.9	2.9	3.9	-1.9	-1.8	-1.8	1.6	-1.5	-1.9	-2.0	-0.8
Father’s age at death	1.6	2.2	4.7	1.0	1.0	1.3	-1.9	2.2	1.2	1.5	1.2
Worrier / anxious feelings	0.1	0.1	0.2	-0.4	-0.3	-0.3	-0.1	0.2	-0.4	-0.3	0.5
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.7	4.5	-1.4	-1.1	-1.3	1.2	0.5	-1.5	-2.1	-0.7
Falls in the last year	0.6	0.8	3.7	0.1	0.5	0.7	-1.9	0.7	0.2	0.0	1.1
Hair/balding pattern: Pattern 3	0.4	0.6	2.1	-0.7	-0.5	-0.3	-0.8	-1.5	-0.8	-0.8	0.5
Number of live births	0.7	1.0	2.2	-0.8	-1.0	-0.8	1.3	-1.1	-0.6	-0.2	-1.5
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.7	0.7	0.4	0.7	-0.6	0.9	0.5	1.1	1.3
Pulse rate	0.5	0.8	1.8	-1.1	-0.8	-0.9	0.1	0.3	-0.9	-1.0	-1.4
Happiness	1.2	1.5	2.0	-1.4	-1.1	-1.4	1.1	-1.0	-1.4	-1.4	-1.0
Noisy workplace	0.7	0.8	2.0	-0.9	-0.9	-1.1	1.4	-0.6	-0.9	-0.9	-0.4
Qualifications: A levels/AS levels or equivalent	0.1	0.3	2.0	-0.5	-0.2	-0.0	-1.4	0.4	-0.3	-0.0	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.1	2.5	1.0	1.1	1.1	-0.8	0.4	0.9	1.1	1.6
Mouth/teeth dental problems: Dentures	0.1	0.1	0.6	-0.2	-0.1	-0.4	-0.1	-0.2	-0.2	-0.4	-0.8
Asthma	0.1	0.1	0.4	0.3	0.2	-0.1	0.7	-0.5	0.3	0.1	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	2.3	-0.1	-0.2	-0.1	0.4	1.5	-0.2	-0.2	-0.1
Medication: Cholesterol lowering	1.3	2.1	7.8	-1.3	-1.0	-0.9	0.3	-2.8	-1.2	-2.0	-0.0
Depression (self-reported)	0.2	0.2	0.8	-0.2	0.3	-0.1	0.7	-0.9	-0.1	0.0	-0.5
Medication: Lansoprazole	0.0	0.1	0.2	0.1	0.3	0.1	-0.2	-0.2	0.2	0.1	-0.4
Prospective memory result	0.5	0.7	1.2	-1.1	-0.9	-0.6	-0.1	-1.1	-0.9	-0.9	0.3
Lung cancer (father)	1.2	1.4	4.1	-1.2	-0.7	-0.9	-0.5	-1.4	-1.0	-2.0	-1.1
Illnesses of mother	0.7	0.9	3.3	-0.7	-0.8	-0.7	0.8	-1.8	-0.6	-0.5	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	2.1	0.6	0.4	0.6	-1.0	1.3	0.5	1.0	1.4
Pulse wave Arterial Stiffness index	0.2	0.2	1.2	0.1	0.1	0.0	-0.2	1.1	0.1	0.6	0.5
Impedance of arm (left)	0.0	0.2	0.6	0.2	0.6	0.3	-0.6	0.8	0.3	0.1	0.2
Arm fat mass (right)	0.1	0.4	0.6	0.6	0.7	0.5	-0.4	0.8	0.6	0.7	0.4
Trunk predicted mass	0.1	0.7	2.0	-0.6	-1.2	-0.6	0.5	1.4	-0.8	-0.4	0.4
Standing height	0.1	1.2	7.5	0.2	-0.7	-0.2	1.0	2.7	0.1	0.3	-0.5
Length of working week for main job	1.0	1.1	2.5	0.8	1.3	1.1	-1.6	0.5	0.7	0.7	1.3
Exposure to tobacco smoke at home	0.7	0.8	1.3	1.1	0.8	0.9	0.7	-0.7	1.0	1.1	-0.7
Breastfed as a baby	0.3	0.4	1.8	0.2	0.6	0.4	-1.3	-0.5	0.3	0.3	0.8
Tense / ‘highly strung’	0.4	0.7	1.2	-1.0	-0.8	-1.0	0.6	-0.4	-0.9	-1.1	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	2.9	-1.5	-1.2	-1.5	1.0	-0.6	-1.5	-1.7	-1.2
Hair/balding pattern: Pattern 4	0.6	1.4	4.5	-0.5	-1.2	-1.0	1.3	-1.1	-0.6	-0.9	-2.1
Birth weight of first child	0.3	0.5	2.5	-0.5	-0.3	-0.3	0.3	-1.6	-0.3	-0.4	-1.0
Peak expiratory flow (PEF)	0.9	2.0	3.6	1.5	1.1	1.5	-1.1	1.5	1.3	1.4	1.9
Pulse wave reflection index	0.4	0.5	2.9	0.1	0.0	0.2	-0.6	-1.0	-0.0	0.3	1.7
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.2	-0.7	-0.4	-0.6	-0.0	0.0	-0.5	-0.4	-1.1
Loud music exposure frequency	1.0	1.1	2.0	1.3	1.2	1.3	0.0	0.2	1.4	1.4	-0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.7	-0.3	-0.4	-0.2	-0.2	-0.1	-0.4	-0.6	0.8
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	4.0	-0.4	-0.4	-0.2	0.1	-2.0	-0.4	-0.2	-0.0
Blood clot in the leg (DVT)	1.7	2.2	3.5	-1.7	-1.2	-1.6	0.9	-1.9	-1.5	-1.5	-1.2
Medication: Paracetamol	0.7	1.2	3.6	-0.6	-1.1	-1.1	1.9	0.0	-0.8	-0.6	-1.6
Headache pain in last month	0.3	0.5	1.4	0.6	0.3	0.7	-0.6	1.2	0.5	0.6	0.4
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	4.9	1.4	0.9	0.9	-0.2	2.2	1.4	1.9	0.3
Glaucoma (self-reported)	0.1	0.2	0.4	-0.4	-0.2	-0.5	-0.6	-0.5	-0.1	0.3	-0.1
Gout (self-reported)	0.3	0.5	0.9	-0.8	-0.8	-0.7	0.6	-0.1	-0.8	-0.9	-0.5
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.4	-0.3	-0.3	-0.4	1.0	-1.2	-0.5	-0.3	0.4
Medication: Amlodipine	2.2	3.0	5.3	-1.3	-1.6	-1.7	2.3	-2.2	-1.1	-1.0	-2.3
Medication: Ventolin 100micrograms inhaler	0.7	0.9	4.8	0.8	0.6	0.7	-0.3	2.2	0.7	0.4	0.4
Birth weight	0.2	0.4	1.8	0.5	0.2	0.1	0.9	0.0	0.5	0.3	-1.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.7	-0.0	0.3	0.1	-0.8	-0.1	-0.1	-0.1	-0.2
High blood pressure (siblings)	0.5	0.7	5.0	-0.1	0.2	-0.2	0.2	-0.6	0.1	-0.2	-2.2
Forced vital capacity (FVC), Best measure	0.1	0.2	0.8	-0.0	-0.4	-0.4	0.9	0.1	-0.2	0.6	-0.1
Body fat percentage	0.1	0.3	0.7	0.7	0.8	0.5	-0.0	0.4	0.8	0.6	-0.4
Leg fat percentage (right)	0.1	0.4	0.7	0.8	0.8	0.6	-0.2	0.1	0.9	0.7	0.2
Arm fat-free mass (right)	0.0	0.2	0.6	-0.0	-0.6	-0.3	0.8	0.3	-0.1	0.2	-0.3
Exposure to tobacco smoke outside home	0.4	0.6	1.2	-1.1	-0.9	-0.6	0.4	-0.2	-1.0	-0.9	-0.3
Comparative body size at age 10	0.5	1.5	3.3	1.3	1.1	0.9	-0.0	1.7	1.4	1.8	-0.1
Number of full brothers	0.6	0.7	1.5	-1.0	-0.8	-0.5	-1.2	0.4	-1.0	-0.5	0.9
Worry too long after embarrassment	0.6	0.9	2.0	-0.7	-1.0	-1.0	1.4	-0.8	-0.7	-0.9	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	1.3	0.0	0.2	0.3	0.3	-0.6	-0.0	0.4	1.1
Wheeze or whistling in the chest in last year	0.0	0.1	0.2	0.5	0.3	0.1	0.4	-0.1	0.3	0.1	-0.1
Number of children fathered	1.6	1.8	2.6	-1.3	-1.5	-1.6	0.8	1.4	-1.2	-1.2	-1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.4	0.4	0.4	0.4	-0.1	-1.2	0.3	0.1	0.5
Age at first live birth	0.4	0.7	1.7	0.8	0.7	1.0	-1.3	-0.3	0.8	0.5	0.8
Pulse wave peak to peak time	0.2	0.2	0.5	-0.3	-0.2	-0.2	0.2	-0.7	-0.3	-0.7	-0.5
Health satisfaction	0.1	0.2	0.3	-0.5	-0.2	-0.5	0.3	0.6	-0.5	-0.2	-0.0
Shortness of breath walking on level ground	1.2	1.4	2.9	1.2	1.4	1.3	-1.7	-0.3	1.2	1.2	0.8
Qualifications: College or University degree	0.2	0.7	2.3	-0.1	-0.1	0.3	-1.1	1.3	-0.1	0.1	1.5
Eye problems/disorders: None of the above	0.4	0.5	1.4	0.6	0.5	0.5	0.6	0.3	0.7	0.8	-1.2
Mouth/teeth dental problems: Loose teeth	1.6	1.9	3.2	-1.5	-1.4	-1.3	0.7	-1.8	-1.6	-1.6	0.5
Emphysema/chronic bronchitis	0.2	0.2	0.8	-0.2	-0.0	-0.1	-0.2	0.9	-0.4	-0.8	0.5
Medication for pain relief, constipation, heartburn	2.5	4.2	5.2	2.1	2.1	2.1	-2.2	1.5	2.1	2.3	2.0
Neck or shoulder pain in last month	0.5	0.7	1.6	0.8	0.7	0.5	1.2	-0.3	0.8	0.4	-1.3
Medication: Blood pressure	0.7	1.2	2.3	-1.3	-0.8	-0.8	-0.4	-1.5	-1.2	-1.4	-0.9
Angina (self-reported)	0.5	0.7	1.7	-0.9	-0.4	-0.5	-0.6	-1.1	-0.7	-1.3	-0.5
Migraine (self-reported)	0.7	0.8	1.6	-1.1	-1.3	-1.1	0.3	0.3	-1.2	-1.0	0.0
Medication: Ibuprofen	0.1	0.1	1.0	0.1	0.2	0.1	0.2	1.0	0.1	0.2	-0.1
Medication: Allopurinol	0.5	0.6	1.3	-0.8	-1.0	-0.8	0.6	0.2	-0.8	-1.2	-0.2
Medication: Omeprazole	1.1	1.3	2.3	-1.4	-1.3	-1.5	0.7	-0.8	-1.5	-1.0	-0.4
Medication: Seretide 50 evohaler	0.5	0.6	2.2	0.3	0.7	0.4	-0.6	-1.5	0.5	0.9	-0.3
Mean time to correctly identify matches	2.4	4.6	6.6	-2.5	-2.3	-2.3	0.8	-1.9	-2.3	-2.6	-1.9
Heart disease (mother)	0.2	0.2	0.5	-0.1	0.0	-0.3	0.7	-0.5	-0.1	-0.5	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.6	0.4	0.6	0.7	-0.5	-0.8	0.4	0.2	0.6
Whole body fat mass	0.0	0.2	0.4	0.4	0.4	0.1	0.4	0.6	0.4	0.5	-0.4
Leg fat mass (right)	0.0	0.1	0.3	0.4	0.4	0.2	0.1	0.5	0.4	0.5	0.1
Arm predicted mass (right)	0.0	0.2	0.8	0.0	-0.6	-0.3	0.9	0.2	-0.1	0.2	-0.4
Pulse rate, automated reading	0.4	1.3	2.1	1.2	1.1	0.9	-0.0	1.0	1.4	1.4	-1.2
Alcohol intake frequency.	0.6	1.4	2.2	-1.2	-1.4	-1.1	1.2	-0.8	-1.4	-1.5	-0.2
Comparative height size at age 10	0.2	0.9	4.3	0.9	0.5	0.6	-0.3	2.1	0.9	0.6	-0.3
Number of full sisters	1.1	1.3	7.1	0.1	-0.3	-0.5	1.6	-0.6	0.2	-0.3	-2.7
Suffer from ‘nerves’	0.2	0.3	1.0	0.3	0.3	0.4	-0.1	-1.0	0.5	0.5	-0.6
Overall health rating	0.1	0.2	0.7	-0.3	-0.2	-0.4	0.5	-0.9	-0.4	-0.7	0.0
Chest pain or discomfort	0.3	0.5	2.0	-0.3	0.1	-0.2	0.2	-1.4	-0.2	-0.6	-1.1
Had major operations	0.3	0.3	0.8	-0.5	-0.6	-0.6	0.6	-0.2	-0.5	-0.5	-0.9
Age at last live birth	0.1	0.2	0.3	0.3	0.3	0.5	-0.6	-0.4	0.3	0.0	0.5
Family relationship satisfaction	0.4	0.5	1.1	-1.1	-0.7	-0.6	-0.5	0.6	-0.9	-1.0	0.2
Leg pain on walking	1.1	1.3	2.1	1.1	1.4	1.2	-1.1	0.5	1.3	1.5	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.4	1.2	0.6	0.6	0.5	0.3	0.9	0.9	-0.3
Commuting to job workplace: Car/motor vehicle	1.0	1.2	2.4	1.5	0.9	1.0	0.9	-0.9	1.4	1.3	-0.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	4.8	-0.6	-0.7	-0.4	-0.2	2.2	-0.7	-0.3	0.8
Medication: Aspirin	1.7	2.2	4.2	-1.8	-1.4	-1.3	0.4	-1.9	-1.7	-2.0	-0.4
Supplements: Vitamin C	1.0	1.2	2.0	-1.1	-1.4	-1.2	1.3	-0.2	-1.2	-0.7	-0.9
Knee pain experienced in last month	0.3	0.4	2.7	0.2	0.0	-0.3	1.6	-0.4	0.1	0.3	-0.6
Hypertension (Self-reported)	0.2	0.6	0.9	0.6	0.9	0.9	-0.9	-0.9	0.7	0.4	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.0	-0.4	-0.3	-0.8	0.9	-0.3	-0.3	0.0	-1.0
Illnesses of father: Heart disease	1.0	1.3	6.4	0.5	0.9	1.1	-2.5	-0.8	0.6	0.6	0.9
Illnesses of siblings: Diabetes	0.7	0.8	2.5	-0.4	-0.7	-0.8	1.1	1.1	-0.4	-0.4	-1.6
Smoking status: Previous	2.4	3.5	5.6	-2.3	-2.1	-2.0	1.2	-1.1	-2.1	-2.4	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	2.5	1.1	0.7	1.1	-0.3	0.9	0.9	1.1	1.6
Whole body fat-free mass	0.1	0.4	2.0	-0.1	-0.7	-0.3	0.5	1.4	-0.4	0.0	0.5
Leg fat-free mass (right)	0.1	0.4	1.8	0.5	0.2	0.4	-0.1	1.3	0.3	0.6	0.7
Arm fat percentage (left)	0.2	0.6	1.3	0.9	1.1	0.8	-0.7	0.4	0.9	0.9	0.3
Average weekly red wine intake	0.8	1.1	2.0	-1.4	-1.4	-0.9	-0.4	-0.7	-1.3	-1.3	0.1
Handedness (chirality/laterality): Left-handed	1.0	1.3	2.5	-1.4	-1.3	-0.9	-0.1	-1.0	-1.4	-1.6	-0.3
Mood swings	0.2	0.3	1.8	0.0	0.0	0.1	0.1	-1.3	-0.0	-0.2	0.7
Loneliness, isolation	1.2	1.7	2.4	-1.2	-1.5	-1.6	1.5	-0.7	-1.2	-1.2	-1.4
Long-standing illness, disability or infirmity	1.8	2.7	4.2	1.8	2.1	1.8	-1.4	-0.5	1.7	1.6	1.7
Ever had bowel cancer screening	0.5	0.6	1.5	1.0	0.8	0.9	-0.2	-0.2	1.2	0.5	-0.7
Diabetes diagnosed by doctor	0.6	1.1	2.4	-1.1	-1.2	-1.1	0.8	-0.1	-1.2	-1.6	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.0	0.0	0.0	-0.0	1.0	-0.9	0.1	0.0	-0.4
Friendships satisfaction	0.3	0.3	0.4	-0.6	-0.6	-0.5	0.4	-0.7	-0.6	-0.6	0.5
Qualifications: nursing, teaching	0.3	0.4	1.1	-0.5	-0.7	-0.6	0.7	-0.3	-0.5	-0.6	-1.1
Commuting to job workplace: Walk	1.2	1.3	5.9	0.8	0.6	0.8	-0.7	2.4	0.6	0.8	1.2
Eye problems/disorders: Cataract	0.7	0.8	1.6	-1.1	-0.8	-0.7	-0.0	-0.1	-1.1	-1.2	1.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.6	0.1	0.1	0.3	-0.0	-0.8	0.0	0.2	0.4
Medication for cholesterol	0.3	0.5	0.8	-0.9	-0.7	-0.6	-0.4	0.7	-0.9	-0.9	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	1.9	-1.3	-1.3	-1.4	1.2	-0.8	-1.3	-1.0	-1.2
Back pain experienced in last month	0.2	0.2	0.9	-0.3	-0.2	-0.2	0.1	0.9	-0.4	-0.2	0.9
Mineral and other dietary supplements	1.8	2.5	3.4	1.8	1.8	1.6	-0.9	-1.8	1.8	1.8	-0.0
Breast cancer (self-reported)	1.2	1.5	7.8	-1.1	-0.7	-0.8	-0.3	-2.8	-0.9	-0.3	-0.6
Asthma (self-reported)	0.1	0.1	0.5	0.1	0.1	-0.1	0.6	-0.7	0.1	-0.0	-0.4
Osteoporosis (self-reported)	0.4	0.5	2.1	0.5	0.9	0.6	-1.4	-0.2	0.7	0.4	-0.4
Osteoarthritis (self-reported)	0.1	0.1	0.3	-0.4	-0.4	-0.4	-0.1	0.1	-0.5	-0.5	0.1
Medication: Aspirin	2.6	3.4	6.2	-2.1	-1.7	-1.7	0.8	-2.5	-2.0	-2.3	-0.7
Medication: Gliclazide	1.2	1.3	2.6	-1.4	-1.2	-1.3	0.7	0.2	-1.4	-1.6	-0.6
Illnesses of father: None of the above (group 1)	0.6	0.8	2.8	-0.3	-0.7	-0.6	1.4	1.7	-0.4	-0.6	-0.0
Smoking status: Current	1.1	1.7	4.7	-1.1	-1.1	-1.2	2.2	-0.8	-1.2	-1.4	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	4.1	0.6	0.7	1.0	-1.8	0.6	0.6	0.7	2.0
Whole body water mass	0.1	0.3	1.5	-0.2	-0.7	-0.3	0.5	1.2	-0.4	-0.0	0.4
Leg predicted mass (right)	0.1	0.4	1.9	0.4	0.2	0.4	-0.2	1.4	0.3	0.5	0.8
Arm fat mass (left)	0.1	0.6	0.9	0.9	0.9	0.8	-0.5	0.7	0.9	0.9	0.4
Number of self-reported non-cancer illnesses	0.2	0.4	1.4	-0.2	-0.1	-0.3	0.8	-1.2	-0.2	-0.4	-0.8
Average weekly champagne plus white wine intake	0.1	0.2	0.5	0.6	0.2	0.2	0.5	0.1	0.6	0.7	-0.3
Miserableness	0.1	0.3	0.5	0.7	0.7	0.5	0.2	-0.3	0.7	0.4	0.2
Guilty feelings	3.1	4.7	7.0	-2.4	-2.6	-2.4	1.8	-1.2	-2.4	-2.5	-1.5
Wears glasses or contact lenses	0.3	0.4	1.5	0.4	0.1	0.0	0.4	0.9	0.5	0.3	-1.2
Ever taken oral contraceptive pill	0.9	1.0	1.8	1.1	1.2	1.2	-0.4	-0.7	1.1	1.3	-0.4
Hearing aid user	0.6	0.7	2.3	0.7	1.0	0.7	-0.6	1.5	0.8	0.4	-0.4
Mother’s age at death	2.8	3.5	5.7	-2.1	-2.4	-2.3	1.4	-0.6	-2.1	-2.2	-1.2
Financial situation satisfaction	0.6	0.7	4.5	0.2	-0.2	-0.3	2.1	-0.3	0.1	-0.1	-0.9
Tinnitus: Yes, now most or all of the time	1.5	1.8	4.0	-1.4	-1.2	-0.9	-0.5	0.2	-1.6	-2.0	1.8
Commuting to job workplace: Public transport	1.3	1.6	3.2	-1.8	-1.2	-1.0	-0.7	0.3	-1.7	-1.6	0.9
Eye problems/disorders: Glaucoma	0.2	0.3	1.3	-0.3	-0.1	-0.6	-0.0	-0.7	-0.0	0.1	-1.1
Medication: Blood pressure	0.3	0.6	1.1	0.9	1.0	0.9	-0.5	0.0	1.0	0.9	0.1
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.7	-0.2	-0.2	-0.5	1.3	1.2	-0.3	0.0	-1.1
Supplements: Fish oil (including cod liver oil)	1.4	1.8	4.1	-1.5	-1.5	-1.3	0.4	2.0	-1.6	-1.3	0.3
High cholesterol (Self-reported)	0.8	1.4	5.3	-0.6	-0.5	-0.7	1.4	-2.3	-0.5	-1.0	-1.2
Medication: Bendroflumethiazide	1.2	1.8	3.9	0.7	1.1	1.2	-2.0	1.9	0.7	0.7	1.5
Medication: Paracetamol	0.6	1.0	2.9	-0.6	-1.0	-1.1	1.7	-0.2	-0.8	-0.3	-1.3
Medication: Lisinopril	0.7	0.9	2.9	0.8	0.9	0.8	-0.7	-1.7	1.0	0.7	-0.6
Medication: Atorvastatin	2.1	2.7	5.0	1.8	1.9	2.0	-0.7	0.5	1.7	1.4	2.2
Illnesses of father: High blood pressure	0.3	0.4	1.1	-0.6	-0.8	-0.6	1.0	0.4	-0.6	0.1	0.1
Alcohol drinker status: Never	0.1	0.1	0.5	0.1	0.1	0.4	-0.7	-0.3	0.2	0.3	0.0
Ever smoked	0.7	1.2	3.5	-0.6	-0.7	-0.7	1.9	-1.4	-0.5	-1.0	-1.4
Basal metabolic rate	0.1	0.3	2.0	0.2	-0.3	0.0	0.3	1.4	-0.0	0.3	0.6
Leg fat percentage (left)	0.1	0.5	0.9	0.9	0.9	0.6	-0.1	0.1	1.0	0.8	-0.1
Arm fat-free mass (left)	0.0	0.2	0.6	-0.1	-0.7	-0.3	0.8	0.6	-0.3	-0.1	0.2
Number of operations (self-reported)	0.5	0.7	1.2	-0.8	-0.9	-1.1	0.9	-0.1	-0.8	-0.5	-1.1
Average weekly beer plus cider intake	0.3	0.4	0.9	-0.4	-0.5	-0.4	0.6	-0.9	-0.5	-0.9	0.2
Irritability	1.4	2.3	4.2	-1.8	-1.4	-1.7	1.3	-0.8	-1.7	-2.0	-0.9
Risk taking	0.4	0.5	0.9	-0.9	-0.9	-0.8	0.6	0.3	-0.8	-0.8	-0.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.1	1.1	0.7	0.6	0.8	0.1	1.1	0.9	-0.8
Fractured/broken bones in last 5 years	0.6	0.7	4.0	0.5	0.5	0.7	-0.6	-0.1	0.4	0.7	2.0
Age started oral contraceptive pill	0.4	0.5	0.9	0.5	0.8	0.7	-0.9	-0.7	0.7	0.7	-0.4
Diastolic blood pressure, automated reading	0.1	0.2	0.3	0.3	0.3	0.4	0.4	-0.5	0.4	0.6	-0.4
Ever depressed for a whole week	0.3	0.3	1.3	-0.4	0.2	0.1	-1.2	-0.0	-0.2	-0.6	0.8
Unable to work because of sickness or disability	0.3	0.4	2.0	-0.1	0.1	-0.0	0.6	-0.8	0.1	0.0	-1.4
Commuting to job workplace: Cycle	1.5	1.8	3.1	-1.7	-1.6	-1.5	0.0	-1.0	-1.8	-1.5	-0.3
Myopia	4.0	5.9	7.8	2.4	2.5	2.8	-2.4	2.2	2.2	2.4	2.4
Vascular/heart problems diagnosed by doctor	0.2	0.5	3.4	0.2	-0.3	-0.2	0.6	1.8	0.1	0.5	-0.1
Cholesterol lowering medication	0.4	0.7	2.3	0.8	0.7	0.3	0.9	-1.5	0.7	0.6	-0.1
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	2.3	-1.4	-1.4	-1.5	0.8	-0.8	-1.5	-1.3	-0.4
Pain experienced in last month	0.3	0.6	3.8	0.3	0.4	0.4	-0.5	-1.9	0.3	0.4	0.2
Supplements: Calcium	2.1	2.3	5.0	-1.7	-2.0	-1.7	0.0	-0.1	-1.8	-2.2	-0.5
Basal cell carcinoma (self-reported)	0.9	1.1	1.9	-0.9	-1.1	-1.1	1.4	-0.3	-1.1	-1.2	-0.6
Heart attack/myocardial infarction (self-reported)	0.9	1.1	3.6	-1.2	-0.7	-0.7	-0.4	-0.9	-1.2	-1.9	0.7
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	4.3	-1.4	-1.0	-1.3	0.5	-2.1	-1.3	-1.2	-1.1
Heart disease (siblings)	0.5	0.6	2.3	0.3	0.8	0.6	-1.5	0.3	0.3	0.6	1.0
Alcohol drinker status: Previous	0.3	0.3	1.9	0.0	-0.3	-0.2	1.4	-0.4	-0.1	-0.3	-0.2
Pack years of smoking	1.0	1.5	3.6	-0.9	-0.9	-1.2	1.6	-1.2	-1.0	-0.6	-1.9
Impedance of whole body	0.0	0.2	0.3	0.5	0.6	0.3	0.1	0.3	0.5	0.3	-0.3
Leg fat mass (left)	0.1	0.2	0.4	0.6	0.5	0.3	0.1	0.5	0.5	0.6	0.0
Arm predicted mass (left)	0.0	0.2	0.6	-0.1	-0.6	-0.3	0.8	0.6	-0.2	0.0	-0.1