Hub : Genes

TNK2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Uterus	0.3920	0.1390	0.00850	0.009	NA	0.019	NA	0.010	2.1e-01	NA	1.3e-01	NA	2.0e-01
2	YFS	Blood	0.0135	0.0073	0.01500	0.004	0.004	0.001	0.006	0.003	1.5e-02	1.2e-02	1.2e-01	0.0029	3.5e-02
3	TCGA	Breast Invasive Carcinoma	0.0396	0.0186	0.00040	0.004	0.020	0.012	NA	0.004	4.7e-02	4.2e-05	1.4e-03	NA	4.1e-02
4	TCGA	Lung Adenocarcinoma	0.0517	0.0243	0.00210	0.033	0.016	0.016	NA	0.023	8.1e-05	5.0e-03	5.0e-03	NA	9.4e-04
5	TCGA	Ovarian Serous Cystadenocarcinoma	0.0700	0.0360	0.00210	0.026	0.019	0.002	NA	0.013	6.5e-03	1.7e-02	2.2e-01	NA	4.2e-02
6	TCGA	Prostate Adenocarcinoma	0.1018	0.0365	0.00002	0.034	0.041	0.052	NA	0.049	1.5e-04	4.1e-05	3.4e-06	NA	6.4e-06
7	TCGA	Thyroid Carcinoma	0.0610	0.0370	0.00550	0.003	0.031	0.020	NA	0.018	1.5e-01	4.4e-04	4.0e-03	NA	6.1e-03
8	TCGA	Uterine Corpus Endometrial Carcinoma	0.5280	0.1440	0.00022	0.042	0.117	0.144	NA	0.106	2.6e-02	3.9e-04	8.3e-05	NA	7.0e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.8	2.8	6.7	-2.0	-1.6	2.6	1.2	1.7	1.4	-0.2	1.7
Bipolar Disorder or Schizophrenia	0.5	1.3	6.4	-2.5	-0.6	0.9	-1.0	1.1	0.9	-0.0	0.3
Depressed Affect (Nagel 2018)	1.4	3.0	8.5	-2.9	-0.8	-0.9	-1.4	-1.1	-1.9	-1.3	-2.3
Depression (Nagel 2018)	0.9	1.4	3.2	-1.8	0.2	0.3	-1.0	-0.3	-1.6	-1.4	-1.5
Intelligence (Savage-Jansen 2018)	0.4	1.3	4.3	-0.9	-1.9	0.7	2.1	0.7	-0.2	-0.3	0.2
Neuroticism (Nagel 2018)	1.0	2.4	5.7	-2.4	-0.9	-0.9	-0.4	-1.0	-2.3	-1.1	-2.1
Schizophrenia (2018)	0.5	1.0	3.2	-1.7	0.6	-1.0	-1.8	0.0	0.0	0.2	-0.9
Schizophrenia vs Biploar Disorder	0.5	0.6	4.4	0.7	2.1	0.0	0.0	0.0	0.0	0.0	0.0
Worry (Nagel 2018)	0.6	1.3	5.0	-1.0	0.2	-0.9	0.1	-0.2	-2.2	-0.6	-1.8
Alzheimer’s Disease (in mother)	0.4	0.4	2.0	-0.0	0.1	-0.3	-0.7	0.2	-0.6	0.7	-1.4
Alzheimer’s Disease (in father)	2.3	2.5	6.0	0.1	0.4	-1.6	-2.5	-1.6	-1.9	-1.1	-1.9
Alzheimer’s Disease (including proxy)	1.1	1.6	4.7	-0.6	-0.4	-1.0	-1.9	-0.8	-1.6	-0.3	-2.2
Crohns Disease (2017)	0.3	0.7	1.5	-0.7	-0.8	0.4	1.2	1.1	0.8	0.8	-0.3
Irritable Bowel Disease (IBD)	0.6	1.5	5.4	-0.4	-0.7	1.3	2.3	1.0	1.2	-0.1	1.1
Ulcerative Colitis (UC)	0.9	1.8	7.4	-0.1	0.1	1.4	2.7	0.6	0.9	-0.8	1.7
Major Depression (MDD)	0.3	0.4	3.0	-1.7	-0.4	0.0	0.0	0.0	0.0	0.0	0.0
Reaction Time	0.6	1.2	2.8	-0.8	0.3	-1.7	-1.1	-0.3	-1.6	0.4	-1.5
Verbal and Numeric Reasoning (VNR)	1.0	2.5	9.2	-1.2	-3.0	1.4	2.1	1.5	0.6	0.5	0.4
Breast Cancer	0.4	1.0	2.6	0.0	0.6	0.6	1.6	-1.4	-0.4	-1.1	1.1
Ovarian Cancer	0.3	0.4	1.1	-1.0	0.0	-0.3	1.0	-0.2	-1.0	0.2	-0.5
Prostate Cancer	1.5	2.2	4.7	-1.6	-0.5	2.2	0.5	1.7	1.9	0.0	1.8
Age at First Birth	0.9	1.4	4.4	0.3	-0.1	2.1	0.5	0.6	1.1	-1.2	1.8
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	1.7	2.4	5.9	1.5	2.4	-0.9	-2.0	0.7	0.2	1.6	-1.8
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.4	0.6	2.4	0.6	-0.7	-0.0	0.2	1.0	0.7	1.6	-0.4
Mean Putamen Volume	0.8	1.0	1.5	-1.1	-0.7	1.0	1.2	1.2	0.8	0.5	1.1
Fasting Glucose	2.1	2.5	6.4	0.4	-1.3	-1.9	-0.7	-1.9	-2.5	-1.1	-1.7
HbA1C	0.4	0.4	1.1	-1.0	-1.1	-0.1	-0.3	0.0	0.1	0.2	-1.1
HDL Cholesterol	1.6	2.6	6.6	0.7	-0.9	-1.5	1.7	-2.4	-2.6	-1.4	-0.8
LDL Cholesterol	0.8	1.3	4.3	0.2	0.4	0.7	0.4	-0.9	-2.1	-2.0	-0.6
Lupus	1.4	2.2	4.4	-1.6	-1.1	-1.9	-0.7	0.8	-1.3	1.6	-2.1
Neuroticism (2016)	2.3	3.3	4.4	-2.1	-0.7	-1.9	-2.1	-2.0	-2.0	-1.6	-1.8
Primary Biliary Cirrhosis	0.4	0.6	3.1	-0.2	0.1	0.1	0.8	-0.3	-1.0	-1.8	-0.2
Rheumatoid Arthritis	1.0	1.4	3.6	-1.4	-1.9	-1.6	-1.2	-0.6	-0.7	-0.0	-1.1
Schizophrenia (2014)	0.5	1.1	4.1	-2.0	-0.1	0.2	-1.2	0.9	1.3	0.4	0.0
Triglycerides	0.5	0.8	2.8	1.7	1.1	0.1	-1.1	0.5	0.8	0.4	-0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	-0.3	0.1	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.3	0.4	1.3	0.2	-1.0	0.2	0.8	-0.5	-0.2	-1.1	0.0
Blood Eosinophil Count	0.5	4.0	7.9	-2.6	-1.9	1.9	2.0	2.8	1.2	1.8	1.3
Blood Platelet Count	0.8	9.1	25.5	-3.3	-2.7	2.6	1.1	5.0	2.8	3.2	1.8
Blood Red Count	2.3	22.7	50.0	6.6	5.7	-1.2	7.1	-4.8	-4.5	-3.2	0.2
Blood White Count	0.7	5.5	15.1	0.5	-0.2	2.2	1.5	3.9	2.8	3.0	2.2
Heel T-Score	0.1	0.9	2.5	0.4	-0.6	0.4	-0.9	1.0	1.3	1.6	-0.5
BMI	0.6	3.3	10.0	1.3	3.2	-2.3	-1.2	-1.3	-1.3	-1.0	-2.0
Height	0.1	2.2	10.9	-3.3	-0.3	-0.1	-2.0	0.4	-0.6	-0.1	-1.6
Waist Hip Ratio (WHR)	0.4	1.7	3.4	-0.9	-1.2	1.3	0.4	1.8	1.7	1.8	0.4
Systolic Blood Pressure	0.5	2.7	6.3	2.3	-0.1	1.4	2.2	0.5	1.6	0.3	2.5
Smoking Status	0.9	2.0	4.5	-2.1	-1.9	-0.9	-0.8	1.0	0.3	1.5	-1.8
Allergy or Eczema	0.4	1.0	2.8	-0.3	-0.4	0.8	1.1	0.8	1.4	0.9	1.7
Cardiovascular Disease	0.3	0.9	3.6	0.5	1.9	1.3	0.9	0.8	-0.7	0.2	-0.0
Hypothyroidism (self reported)	0.2	0.4	1.4	0.4	-0.7	-0.4	0.2	0.9	0.4	1.2	-0.4
Respiratory disease	4.0	8.8	15.9	-4.0	-3.0	3.0	1.7	3.2	3.2	1.4	3.3
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.8	-1.5	-1.7	-0.2	-0.6	0.8	0.3	0.3	-0.2
Lung FEV1/FVC ratio	0.4	2.2	8.9	3.0	2.2	0.9	1.1	0.6	-0.6	0.7	-0.4
Lung FVC	0.9	4.8	12.3	1.5	-2.6	-3.5	-1.2	-1.8	-1.8	0.8	-3.0
Neuroticism	1.0	2.4	5.9	-1.8	-0.8	-0.8	-1.1	-1.2	-2.4	-1.8	-1.8
Chronotype (morning person)	0.3	0.7	4.7	-0.2	0.1	-0.9	2.2	-0.0	0.2	0.4	-0.3
Hair Pigment	0.1	2.3	14.7	-0.4	0.6	1.6	3.8	0.4	-0.7	-0.3	0.5
Tanning	0.3	3.5	10.8	-0.6	-1.0	-3.3	-0.9	-2.3	-2.2	0.3	-2.0
Hand grip strength (left)	0.3	0.7	2.7	1.6	1.5	0.3	-0.3	0.1	-0.8	0.2	0.2
Number of treatments/medications taken	1.1	1.9	3.8	-1.7	-1.6	0.7	-1.4	2.0	0.9	1.7	-0.1
Average weekly spirits intake	0.1	0.2	0.4	-0.1	-0.5	-0.2	0.5	-0.4	-0.5	-0.2	0.6
Sensitivity / hurt feelings	0.2	0.4	0.7	-0.6	-0.5	-0.0	0.7	-0.5	-0.8	-0.8	0.6
Frequency of depressed mood in last 2 weeks	0.6	0.8	1.7	-1.0	-0.1	0.6	-1.0	-0.2	-1.3	-1.3	-0.8
Hearing difficulty/problems: Yes	1.0	1.5	2.9	-1.7	-1.6	-1.6	-0.9	-1.4	-0.5	-0.3	-1.0
Relative age of first facial hair	0.3	0.6	2.6	-1.6	-0.3	-0.3	-0.3	0.4	1.2	0.7	-0.5
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	6.9	-2.6	-1.4	-0.3	-0.1	0.3	-0.1	-0.6	-1.0
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.8	-1.3	0.5	-0.3	-0.2	0.3	-0.4	0.2	-0.3
Ever had hysterectomy (womb removed)	1.8	2.0	4.5	-2.1	-1.1	2.0	0.4	1.3	1.1	-0.2	1.8
Systolic blood pressure, automated reading	0.4	1.2	2.7	1.5	1.1	0.4	1.2	-0.6	1.1	-0.2	1.6
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.2	0.5	-1.1	-1.0	-0.5	-0.3	1.1	0.1	0.9
Angina	0.7	0.9	5.4	-0.1	-0.2	-0.7	-2.3	-0.1	0.4	0.2	-1.1
Medication for hormone replacement therapy	0.3	0.3	0.8	0.1	0.9	0.3	-0.5	0.0	-0.5	-0.9	0.5
Vitamin and mineral supplements	1.0	1.3	2.9	1.2	1.2	0.4	0.6	-1.5	1.5	-0.2	1.7
Supplements: Zinc	0.8	0.9	3.3	0.3	0.5	-0.3	-1.8	0.8	0.1	1.0	-1.4
Medication: Co-codamol	0.7	0.8	4.7	-2.2	-0.4	-0.0	-0.5	0.8	0.7	0.1	0.6
Medication: Metformin	0.7	1.0	3.5	-1.9	-1.3	-0.5	-0.7	0.8	0.6	1.0	-0.4
Diabetes (father)	1.1	1.4	3.9	-0.6	-0.6	1.3	0.5	2.0	2.0	0.3	0.6
Diabetes (mother)	0.6	0.8	1.7	0.5	-1.3	-1.0	-1.3	0.2	0.8	0.9	-0.5
Severe depression (siblings)	1.2	1.3	4.5	-0.3	-1.5	-0.6	-1.3	0.5	-1.2	0.0	-2.1
Pack years adult smoking proportion	0.3	0.4	2.1	0.3	0.3	-0.0	-1.5	0.8	0.2	0.6	-0.4
Impedance of leg (right)	0.8	3.7	6.8	-2.1	-2.6	2.3	1.2	2.3	1.6	1.3	1.5
Leg fat-free mass (left)	0.6	2.9	8.3	-0.2	2.9	-1.5	-1.8	-0.8	-1.9	-0.6	-2.2
Trunk fat percentage	0.6	2.5	10.2	-0.3	3.2	-1.2	-0.8	0.1	-1.9	-0.5	-2.0
Hand grip strength (right)	0.2	0.5	1.9	1.2	1.4	0.1	-0.7	-0.2	-0.5	0.4	0.3
Townsend deprivation index at recruitment	0.4	0.6	1.6	-0.9	-0.6	-1.1	-1.3	-0.2	-0.5	-0.1	-0.8
Current tobacco smoking	1.6	2.5	5.3	-2.2	-2.0	-2.0	0.0	-0.2	-1.5	0.1	-2.3
Average weekly fortified wine intake	1.3	1.5	2.7	1.6	1.6	-1.0	-0.3	-1.7	-1.0	-1.2	-0.4
Maternal smoking around birth	0.4	0.5	2.3	1.5	0.7	-0.1	-0.8	0.0	0.3	0.3	-0.8
Fed-up feelings	0.6	1.0	2.3	-0.2	-0.4	-1.0	-0.6	-1.5	-1.3	-1.5	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	3.6	-1.4	-1.4	-0.5	-1.9	-0.4	-1.9	-1.3	-1.7
Relative age voice broke	0.3	0.5	2.0	-1.4	0.5	0.9	0.3	0.5	0.8	-0.1	-0.5
Taking other prescription medications	1.5	2.3	5.7	-2.3	-0.6	2.2	-0.3	2.4	1.0	0.7	0.9
Age when periods started (menarche)	0.4	0.9	2.5	-1.6	1.5	0.1	-0.7	0.3	0.7	0.8	0.8
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.7	-1.3	0.6	1.6	-0.6	1.5	1.5	0.4	1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.3	0.3	-0.1	-1.1	-0.3	-0.6	-0.8	-0.6	-0.9
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	4.1	-0.5	-1.1	0.8	-0.4	2.0	0.9	1.9	-0.4
Qualifications: CSEs or equivalent	0.6	0.8	1.9	0.1	-1.1	0.1	-0.1	1.2	0.7	1.4	-1.0
Serious illness, injury or assault to yourself	2.2	2.6	5.9	-2.4	-1.8	-0.4	-2.4	0.4	-0.4	-0.1	-2.3
High blood pressure	0.1	0.4	1.4	1.2	0.9	-0.5	-0.1	-0.0	-0.6	0.1	-0.4
Hayfever, allergic rhinitis or eczema	0.6	1.4	2.7	-0.5	-1.6	0.5	0.3	1.5	1.5	1.5	0.8
Multivitamins +/- minerals	0.9	1.1	3.4	-1.1	-0.8	-1.0	-0.3	0.9	-1.4	-0.3	-1.8
Stomach or abdominal pain in last month	2.0	2.5	7.0	-1.0	-1.7	-1.6	-1.2	1.2	1.8	2.6	0.4
Supplements: Glucosamine	0.9	1.1	2.4	-0.2	-0.3	1.3	1.4	1.5	1.3	0.7	0.6
Diverticular disease/diverticulitis (self-reported)	1.2	1.4	3.1	-1.2	-1.8	-0.8	1.0	0.1	-1.7	0.3	-1.4
Medication: Atenolol	1.1	1.4	4.8	2.2	1.4	1.5	-0.3	0.4	0.2	-0.5	1.4
Medication: Levothyroxine sodium	0.7	1.2	1.9	1.4	-0.7	1.0	1.0	1.1	1.4	0.7	1.3
Sitting height	0.3	2.0	3.2	-1.1	1.0	-1.6	-1.7	-1.4	-1.7	-0.4	-1.8
Chronic bronchitis/emphysema (father)	0.4	0.4	1.6	-0.4	-0.5	-1.3	-0.2	0.0	0.6	0.6	-0.8
High blood pressure (mother)	0.3	0.5	1.9	0.8	1.4	-0.6	-0.0	-0.9	-0.1	0.1	-0.0
Body mass index (BMI)	0.8	3.3	10.4	0.9	3.2	-2.0	-1.2	-0.5	-1.7	-0.4	-2.5
Impedance of leg (left)	0.5	2.3	7.1	-1.9	-2.7	1.3	1.1	1.7	0.7	1.0	0.7
Leg predicted mass (left)	0.6	3.0	8.9	-0.3	3.0	-1.5	-1.9	-0.8	-1.9	-0.7	-2.1
Trunk fat mass	0.8	3.3	12.5	-0.5	3.5	-1.4	-1.3	-0.0	-2.1	-0.4	-2.4
Waist circumference	0.4	1.6	5.6	0.0	2.4	-1.2	-0.8	0.4	-1.1	0.0	-1.9
Number of incorrect matches in round	0.1	0.2	0.5	-0.4	0.5	0.5	0.1	0.1	0.5	0.7	0.4
Past tobacco smoking	0.9	1.7	4.4	2.1	1.6	1.2	1.4	-0.3	-0.2	-1.1	1.5
Alcohol usually taken with meals	0.3	0.4	0.8	-0.7	0.4	0.6	0.7	-0.9	-0.3	-0.3	0.9
Nervous feelings	0.4	0.8	3.5	-0.6	-0.6	-0.9	-0.2	-0.9	-1.9	-0.7	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.6	-1.3	-1.0	-0.2	-1.6	0.6	-0.4	0.4	-1.2
Hearing difficulty/problems with background noise	0.8	1.2	3.3	-1.6	-1.8	-1.6	0.1	-1.0	-0.4	-0.1	-0.4
Hair/balding pattern: Pattern 2	0.6	0.8	2.6	1.1	0.5	0.8	1.6	0.9	0.2	0.4	0.7
Had menopause	1.0	1.3	3.1	-0.7	-0.0	0.2	1.8	0.8	1.5	1.5	1.1
Had other major operations	0.5	0.6	1.1	-1.1	-1.0	-0.7	-0.1	1.0	0.7	0.8	-0.4
Forced vital capacity (FVC)	0.3	1.3	3.9	0.4	-0.4	-1.5	0.1	-1.4	-2.0	-0.3	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	3.2	0.0	-0.0	-1.8	-0.6	-1.5	-0.2	-0.5	-0.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.4	-1.1	-0.7	0.1	-1.2	-0.5	-0.5	-0.9	-0.3
Qualifications: None of the above	0.5	1.2	5.5	-0.5	0.2	-1.1	-2.4	-0.3	1.4	0.2	-0.1
Financial difficulties in last 2 years	4.2	5.7	15.8	-1.1	-1.5	-2.8	-3.1	-1.1	-2.7	-0.3	-4.0
Mouth/teeth dental problems	2.2	3.3	6.7	2.6	2.4	0.1	2.1	-2.0	-0.9	-1.9	1.0
Heart attack	0.4	0.5	3.0	-0.5	0.4	0.0	-1.7	0.1	-0.2	-0.1	-0.5
Allergy	2.0	4.6	12.3	2.8	3.5	-0.7	1.6	-2.0	-2.5	-1.7	-0.7
Pain all over the body in last month	1.3	1.4	2.4	-1.4	-1.4	-1.5	-1.5	-0.8	-0.2	-0.9	-0.9
Diabetes (self-reported)	0.5	0.7	1.7	-1.3	-1.3	0.3	-0.4	-0.1	0.9	-0.6	0.8
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.0	-0.1	0.0	0.9	-0.4	0.8	1.0	0.9	0.6
Medication: Ramipril	1.5	1.9	7.7	0.5	2.8	0.7	-0.1	-0.5	1.1	-1.0	2.1
Medication: Simvastatin	0.5	0.8	4.5	0.1	0.5	-0.2	0.2	0.3	-2.1	-0.2	-1.2
Fluid intelligence score	0.8	1.6	7.3	-1.0	-2.7	0.8	0.9	0.9	1.0	0.7	0.6
Illnesses of siblings	1.6	2.3	5.1	-1.3	0.3	0.2	-2.3	1.7	1.9	2.3	-0.1
Neuroticism score	0.9	1.9	4.4	-2.1	-1.3	-0.4	-0.6	-1.2	-2.0	-1.4	-1.1
Weight	0.7	3.6	10.8	-0.3	3.3	-1.9	-1.4	-0.4	-2.3	-0.5	-2.6
Impedance of arm (right)	0.8	3.6	8.6	-2.4	-1.6	2.9	2.3	1.1	0.1	-1.1	2.0
Arm fat percentage (right)	0.6	2.5	10.2	0.1	3.2	-0.8	-0.5	-0.3	-2.2	-1.1	-1.7
Trunk fat-free mass	0.4	2.2	4.0	-0.8	1.9	-1.4	-1.3	-1.1	-2.0	-1.0	-1.9
Hip circumference	0.8	3.6	8.5	-0.3	2.9	-2.0	-0.9	-0.7	-2.6	-1.0	-2.6
Time employed in main current job	0.8	0.9	2.0	-1.0	0.1	1.2	-0.7	1.4	1.3	0.9	0.2
Alcohol intake versus 10 years previously	0.3	0.4	1.2	0.2	0.5	0.8	0.5	0.5	-1.1	-0.4	-0.6
Father’s age at death	0.5	0.6	2.9	-0.6	-0.6	0.6	0.4	-0.8	-0.4	-1.7	0.1
Worrier / anxious feelings	0.4	0.7	2.0	-1.1	-1.3	-0.2	1.4	-0.3	-0.4	-0.1	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	3.0	-1.7	-1.6	-0.0	-1.4	1.1	1.1	0.9	0.4
Falls in the last year	1.4	1.8	5.0	-2.2	-2.1	-1.3	-0.4	-1.3	-0.7	-0.8	-1.0
Hair/balding pattern: Pattern 3	0.2	0.4	1.0	1.0	-0.6	-0.4	0.4	-0.4	-1.0	-0.2	0.2
Number of live births	0.7	1.0	3.2	1.0	0.6	0.9	0.9	-0.6	0.3	-1.2	1.8
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	5.8	1.3	0.3	-1.3	-0.1	-1.4	-2.4	-0.3	-1.6
Pulse rate	0.9	1.5	6.9	2.6	0.4	1.4	0.5	1.4	0.2	0.2	0.8
Happiness	0.4	0.5	1.1	-0.8	-1.0	0.3	0.8	1.1	0.1	0.8	-0.5
Noisy workplace	0.3	0.3	1.5	-1.2	0.8	0.0	-0.2	0.1	0.3	0.4	0.5
Qualifications: A levels/AS levels or equivalent	0.5	1.2	5.0	-0.8	-0.5	0.1	0.5	-1.5	-0.8	-2.2	0.6
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.6	3.4	-1.1	-1.4	1.9	1.6	0.6	-0.5	-1.7	0.5
Mouth/teeth dental problems: Dentures	1.8	3.0	7.3	-2.6	-2.1	-0.5	-2.7	0.7	1.7	1.0	-1.1
Asthma	3.1	6.1	13.9	-3.7	-3.3	2.2	0.7	2.2	2.8	0.8	2.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.8	0.3	-0.9	-0.7	-1.3	-0.5	0.3	0.2	-0.5
Medication: Cholesterol lowering	0.6	0.9	2.7	0.3	0.6	-0.1	-1.0	-0.8	-1.6	-1.4	-0.7
Depression (self-reported)	0.8	0.9	3.0	-1.7	-0.1	1.4	-0.2	0.1	-1.1	-1.1	0.2
Medication: Lansoprazole	0.2	0.2	0.6	-0.8	0.1	-0.2	-0.5	-0.6	-0.1	-0.7	0.5
Prospective memory result	1.7	2.0	5.5	2.0	1.6	0.4	0.4	-0.9	1.2	-1.2	2.4
Lung cancer (father)	0.6	0.7	1.4	1.2	1.2	-0.2	-0.7	-1.1	-0.1	-0.7	0.6
Illnesses of mother	0.8	1.0	2.4	-1.6	-0.8	0.9	1.2	1.0	-1.1	-0.8	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	0.9	2.1	1.2	0.0	-1.1	-0.2	-1.2	-1.4	0.1	-1.0
Pulse wave Arterial Stiffness index	2.4	2.8	8.2	-0.1	-1.0	2.0	2.4	1.0	1.4	-0.9	2.9
Impedance of arm (left)	0.7	3.4	9.5	-2.1	-1.7	3.1	1.8	1.3	0.6	-0.6	2.1
Arm fat mass (right)	0.8	3.1	11.3	-0.5	3.4	-1.3	-1.1	-0.2	-2.1	-0.7	-2.4
Trunk predicted mass	0.4	2.2	3.9	-0.8	2.0	-1.3	-1.3	-1.1	-2.0	-1.0	-1.8
Standing height	0.1	1.1	7.2	-2.7	0.6	0.6	-0.1	0.4	-0.8	-0.3	0.2
Length of working week for main job	0.1	0.1	0.4	-0.4	0.0	-0.2	-0.4	-0.1	-0.2	0.6	-0.3
Exposure to tobacco smoke at home	0.9	1.0	3.6	0.4	-1.1	-0.6	0.4	1.4	-0.3	1.9	-0.7
Breastfed as a baby	0.6	0.7	3.1	-1.8	-0.1	0.9	0.7	1.2	0.0	-0.1	-0.4
Tense / ‘highly strung’	0.7	1.1	3.1	-1.8	-1.4	0.3	-0.9	1.1	-0.7	1.0	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.7	-1.3	-1.6	-0.1	-1.3	1.0	0.1	0.4	-0.9
Hair/balding pattern: Pattern 4	1.1	2.6	5.1	-2.0	0.1	2.2	-0.2	2.2	2.3	0.6	1.4
Birth weight of first child	1.3	2.4	4.0	-2.0	-0.9	1.3	-0.9	1.9	2.0	1.4	1.4
Peak expiratory flow (PEF)	1.2	2.7	8.5	0.6	-1.1	-1.3	-1.0	-2.0	-2.9	-0.9	-2.0
Pulse wave reflection index	1.8	2.3	4.5	-1.2	-1.2	1.6	2.0	1.6	1.1	0.2	2.1
Ever highly irritable/argumentative for 2 days	1.2	1.4	3.9	-1.8	-1.0	-0.5	-1.1	0.9	-0.7	0.6	-2.0
Loud music exposure frequency	0.7	0.8	2.2	0.8	-0.0	0.3	0.9	0.9	-1.2	0.6	-1.5
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	3.1	-0.2	-1.7	-0.1	1.8	0.3	-1.1	0.1	-0.1
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	5.9	-2.4	-2.1	0.1	-0.8	1.0	0.0	0.9	-0.6
Blood clot in the leg (DVT)	3.3	4.3	16.2	-2.6	-4.0	-1.4	-2.7	0.0	0.6	0.7	-1.0
Medication: Paracetamol	0.3	0.5	0.9	0.6	0.3	-1.0	-0.9	-0.5	-0.7	-0.1	-1.0
Headache pain in last month	0.2	0.4	1.4	-1.2	-0.4	0.3	0.1	-0.6	0.4	-0.5	0.8
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.4	-0.6	-1.1	0.3	1.2	0.7	1.1	1.0	0.5
Glaucoma (self-reported)	0.4	0.5	1.8	0.7	1.3	0.6	0.2	-0.1	1.0	-0.3	0.1
Gout (self-reported)	2.9	4.0	10.7	0.0	-1.2	2.3	0.6	2.2	3.3	1.1	2.9
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	4.2	0.7	0.0	0.2	0.4	1.8	1.9	2.1	0.5
Medication: Amlodipine	0.9	1.2	2.8	1.3	0.7	0.7	0.1	1.7	1.3	1.0	1.3
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.2	-0.6	-0.8	0.6	-0.5	1.8	1.2	1.8	0.4
Birth weight	0.3	0.6	2.7	-0.4	-0.3	-1.6	0.5	-1.1	-0.6	-0.0	0.5
Chronic bronchitis/emphysema (mother)	1.1	1.2	4.1	1.4	0.8	0.0	-0.1	1.5	0.9	2.0	-0.2
High blood pressure (siblings)	2.8	4.0	8.6	1.9	2.1	1.0	2.2	-2.2	-2.0	-2.9	1.1
Forced vital capacity (FVC), Best measure	0.3	1.1	2.7	0.1	-0.9	-1.5	-0.1	-1.6	-1.4	-0.2	-0.9
Body fat percentage	0.7	2.6	10.0	-0.2	3.2	-1.3	-0.9	0.2	-1.9	-0.2	-2.1
Leg fat percentage (right)	0.6	2.1	7.8	-0.3	2.8	-1.2	-1.2	0.5	-1.1	0.5	-2.1
Arm fat-free mass (right)	0.7	3.4	7.0	-0.2	2.6	-2.1	-2.1	-0.9	-1.8	-0.2	-2.6
Exposure to tobacco smoke outside home	0.9	1.1	4.9	-2.2	-0.8	-1.6	0.4	-0.6	-0.4	0.1	-0.4
Comparative body size at age 10	1.8	4.9	9.1	3.0	2.2	-1.1	-2.1	-2.0	-2.3	-2.1	-2.5
Number of full brothers	0.7	0.8	2.3	-1.5	-0.3	1.3	-0.4	1.4	0.8	-0.1	0.1
Worry too long after embarrassment	0.2	0.4	1.0	-0.6	-1.0	0.2	0.1	-0.9	-0.4	-0.9	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	2.4	3.2	12.2	-1.6	0.5	0.8	-0.4	-1.4	-2.8	-3.5	0.1
Wheeze or whistling in the chest in last year	0.5	0.9	3.4	-1.9	-0.8	0.5	-0.1	0.8	1.2	0.2	0.8
Number of children fathered	0.1	0.2	0.4	0.1	-0.3	0.3	0.2	-0.6	0.2	-0.5	0.6
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.7	5.9	-0.5	-0.7	1.0	2.4	-0.8	-0.6	-1.9	1.1
Age at first live birth	1.0	1.8	4.4	1.4	0.1	2.1	1.3	0.7	1.6	-0.4	1.7
Pulse wave peak to peak time	2.2	2.6	7.2	0.1	1.1	-1.8	-2.3	-1.0	-1.5	0.7	-2.7
Health satisfaction	0.9	1.1	3.8	-1.0	0.1	1.9	0.9	1.7	0.4	0.2	0.6
Shortness of breath walking on level ground	0.3	0.3	1.0	0.1	0.7	-0.6	0.4	-0.3	-1.0	-0.6	-0.2
Qualifications: College or University degree	0.4	1.1	4.0	-0.3	-0.5	0.9	1.6	-0.8	-0.6	-2.0	0.6
Eye problems/disorders: None of the above	1.3	1.5	5.1	-0.7	-1.1	-1.3	0.0	-1.0	-2.3	-1.1	-1.3
Mouth/teeth dental problems: Loose teeth	0.7	0.8	2.5	0.7	0.1	-0.7	-1.0	1.2	0.4	1.6	-0.8
Emphysema/chronic bronchitis	0.4	0.5	2.1	-1.5	0.5	0.6	-0.1	0.9	-0.3	-0.1	-0.5
Medication for pain relief, constipation, heartburn	0.6	1.0	2.5	0.9	1.5	1.0	1.6	-0.4	-0.5	-0.7	0.8
Neck or shoulder pain in last month	2.1	3.0	9.3	-3.1	-2.5	-0.9	-1.3	1.1	0.4	1.6	-1.4
Medication: Blood pressure	0.5	0.8	3.0	1.0	1.7	-0.1	-0.6	-0.7	-0.3	-1.2	0.4
Angina (self-reported)	0.5	0.7	4.1	-0.1	-0.1	-0.6	-2.0	-0.4	0.3	-0.3	-0.8
Migraine (self-reported)	0.6	0.8	1.5	-1.0	-0.4	-1.2	-0.1	-1.2	-1.1	-0.2	-0.9
Medication: Ibuprofen	0.4	0.5	1.7	1.3	0.1	-0.6	-1.1	-0.4	0.4	0.6	-0.2
Medication: Allopurinol	2.0	2.7	8.6	-0.0	0.0	2.4	-0.2	1.8	2.9	0.9	1.8
Medication: Omeprazole	0.7	0.8	1.8	-0.3	-1.2	0.4	0.7	1.2	1.0	1.3	0.6
Medication: Seretide 50 evohaler	1.4	1.7	5.0	-2.2	-1.0	-0.2	0.2	0.8	-0.5	1.7	-1.8
Mean time to correctly identify matches	0.4	0.7	1.9	-1.2	0.6	-1.0	-1.4	0.0	-0.5	0.5	-0.8
Heart disease (mother)	0.5	0.7	3.3	0.3	0.1	0.6	0.2	-0.1	1.8	0.4	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	4.3	0.3	-1.6	-0.2	-0.4	0.5	-1.0	0.1	-2.1
Whole body fat mass	0.9	3.9	12.6	-0.5	3.5	-1.7	-1.5	-0.0	-2.2	-0.3	-2.8
Leg fat mass (right)	0.8	3.0	10.8	-0.4	3.3	-1.5	-1.6	0.2	-1.7	0.1	-2.4
Arm predicted mass (right)	0.6	3.1	8.0	-0.4	2.2	-2.1	-2.2	-0.5	-1.5	0.2	-2.8
Pulse rate, automated reading	0.2	0.6	2.7	0.3	0.6	-0.7	-1.6	0.4	0.0	0.8	-0.6
Alcohol intake frequency.	0.6	1.3	7.0	1.1	2.6	0.0	-0.1	1.0	-0.9	0.3	-0.4
Comparative height size at age 10	0.5	2.7	9.5	-0.2	1.4	-0.9	-0.4	-1.9	-3.1	-1.8	-1.5
Number of full sisters	0.8	1.0	2.8	0.6	-1.6	-1.3	-0.5	0.1	0.5	1.7	-0.7
Suffer from ‘nerves’	0.7	1.1	3.2	-0.8	-0.5	-1.5	-0.5	-0.5	-1.8	-0.3	-1.4
Overall health rating	1.8	3.8	10.7	-2.5	-0.7	1.0	-1.0	3.3	1.3	3.1	-0.0
Chest pain or discomfort	1.4	2.1	5.2	-1.9	-0.6	0.4	-2.3	1.7	0.4	1.8	-1.0
Had major operations	1.0	1.1	2.8	-0.3	1.7	-0.1	0.3	-1.7	-1.0	-1.5	0.3
Age at last live birth	2.0	2.8	7.9	0.8	0.6	2.8	1.0	1.3	2.2	-0.0	2.5
Family relationship satisfaction	0.2	0.3	0.7	-0.1	0.6	-0.8	0.1	0.2	-0.6	0.5	-0.6
Leg pain on walking	0.8	1.0	3.1	-0.6	0.6	0.6	0.7	1.6	0.8	1.8	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.8	0.3	0.8	-0.9	-0.1	-0.3	-0.1	0.4	-0.2
Commuting to job workplace: Car/motor vehicle	0.5	0.5	1.7	0.7	0.6	0.1	-0.4	1.1	0.3	1.3	0.4
Illness, injury, bereavement, stress in last 2 years	3.8	4.6	15.4	2.5	1.6	1.4	2.3	0.2	2.2	0.5	3.9
Medication: Aspirin	0.6	0.8	2.3	-0.2	0.1	1.5	-0.1	0.5	0.7	-1.1	1.3
Supplements: Vitamin C	0.8	1.0	4.2	-0.8	0.0	0.0	-1.1	-0.0	-2.0	-0.5	-1.2
Knee pain experienced in last month	0.3	0.4	2.3	-0.4	1.5	0.2	0.5	0.4	-0.2	0.2	-0.7
Hypertension (Self-reported)	0.1	0.4	0.9	0.9	0.9	-0.6	-0.3	-0.2	-0.8	-0.0	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	4.4	-0.8	-0.5	0.7	2.1	1.1	-0.4	0.7	0.3
Illnesses of father: Heart disease	1.1	1.6	4.3	2.0	0.4	0.2	0.9	-1.0	-1.5	-2.1	0.1
Illnesses of siblings: Diabetes	0.4	0.5	1.8	0.7	-1.3	-0.7	-1.0	0.3	-0.1	0.5	-0.5
Smoking status: Previous	0.6	1.0	2.5	-1.1	-0.6	-0.1	-1.3	0.9	1.0	1.6	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	3.8	-0.8	-0.2	-0.2	-0.0	-1.4	-0.9	-1.9	0.5
Whole body fat-free mass	0.5	3.0	6.3	-0.4	2.5	-1.8	-1.7	-1.1	-2.1	-0.8	-2.2
Leg fat-free mass (right)	0.6	3.3	8.2	-0.1	2.9	-1.8	-1.8	-0.9	-2.2	-0.7	-2.3
Arm fat percentage (left)	0.6	2.2	9.8	0.1	3.1	-0.6	-0.7	-0.0	-1.9	-0.8	-1.7
Average weekly red wine intake	1.4	2.0	4.4	-2.0	-0.5	0.8	1.6	-1.4	-2.1	-1.6	0.3
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	0.0	0.6	0.2	0.3	0.8	-0.1	0.7	-0.3
Mood swings	1.0	1.8	5.5	-2.3	-1.9	-0.6	-0.6	0.2	-0.8	1.1	-1.6
Loneliness, isolation	2.1	2.9	8.1	-1.7	-1.6	0.2	-2.0	-1.0	-1.6	-2.9	-1.5
Long-standing illness, disability or infirmity	4.0	6.1	14.4	-3.3	-1.4	2.6	-0.6	3.8	2.9	2.1	1.2
Ever had bowel cancer screening	1.2	1.4	3.2	-0.3	-0.2	-0.1	1.5	0.9	1.8	1.8	1.2
Diabetes diagnosed by doctor	0.7	1.1	2.8	-1.1	-1.7	0.2	-0.1	0.9	1.5	0.5	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.1	-1.0	-0.5	-0.2	-0.5	-0.4	0.8	-0.6	0.2
Friendships satisfaction	0.9	1.2	3.0	1.7	0.1	-0.6	1.7	0.6	-1.2	0.9	-0.9
Qualifications: nursing, teaching	0.5	0.8	2.2	-1.0	-1.0	1.5	-0.5	0.9	0.7	0.1	0.8
Commuting to job workplace: Walk	0.6	0.6	2.4	-0.4	-1.6	0.4	1.2	0.3	-0.6	-0.8	0.0
Eye problems/disorders: Cataract	1.2	1.4	3.1	1.0	0.6	1.8	0.9	1.0	1.3	0.7	1.7
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	1.9	-0.9	-1.4	-1.0	0.2	0.9	-0.9	1.1	-1.0
Medication for cholesterol	0.3	0.4	1.7	0.2	-0.0	0.0	0.1	-1.2	-0.1	-1.3	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.3	0.0	-0.4	-1.0	-0.6	-1.2	0.3	-0.3	0.3
Back pain experienced in last month	0.8	1.1	3.2	-0.8	0.5	0.6	0.5	1.7	1.1	1.8	-0.3
Mineral and other dietary supplements	0.6	0.8	1.8	1.4	1.1	-0.4	0.4	-1.3	-0.6	-0.8	0.3
Breast cancer (self-reported)	0.5	0.5	1.7	-1.3	1.0	-0.9	-0.8	-0.4	0.0	-0.3	-0.4
Asthma (self-reported)	3.2	6.4	13.8	-3.7	-3.6	2.1	0.6	2.5	2.8	1.0	2.3
Osteoporosis (self-reported)	0.5	0.6	1.8	-0.2	0.1	0.5	1.2	-0.3	1.1	0.1	1.3
Osteoarthritis (self-reported)	0.6	0.8	2.8	0.7	1.2	0.2	-0.4	1.0	1.7	0.7	0.2
Medication: Aspirin	0.4	0.6	2.0	-0.4	0.3	1.4	-0.2	0.5	0.5	-1.1	0.8
Medication: Gliclazide	0.5	0.5	1.8	-0.0	0.5	-1.3	-0.9	-0.0	0.7	1.0	0.1
Illnesses of father: None of the above (group 1)	0.7	0.8	4.7	-0.2	-0.0	0.3	0.0	1.1	0.7	2.2	0.1
Smoking status: Current	1.8	2.8	6.0	-2.2	-2.1	-2.1	0.0	-0.3	-1.7	-0.2	-2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.6	5.0	1.8	0.2	-2.2	0.6	-1.7	-0.6	0.2	-1.1
Whole body water mass	0.5	2.8	6.6	-0.3	2.6	-1.7	-1.6	-1.1	-2.0	-0.9	-2.1
Leg predicted mass (right)	0.6	3.1	8.1	-0.1	2.8	-1.7	-1.8	-0.9	-2.1	-0.8	-2.2
Arm fat mass (left)	0.7	2.8	10.5	-0.4	3.2	-1.2	-0.9	-0.2	-2.0	-0.8	-2.2
Number of self-reported non-cancer illnesses	1.5	2.6	7.6	-1.7	-1.4	1.1	-0.5	2.8	1.5	2.2	0.3
Average weekly champagne plus white wine intake	0.7	0.9	2.8	0.2	-0.4	-1.0	1.7	-1.4	-0.6	-0.9	-0.2
Miserableness	1.6	2.7	4.9	-1.8	-0.8	-2.0	-1.7	-1.7	-1.6	-0.9	-2.2
Guilty feelings	0.3	0.4	1.1	-0.8	-1.0	0.4	-1.1	-0.2	0.1	-0.7	-0.2
Wears glasses or contact lenses	1.5	1.7	5.3	1.5	1.2	0.9	1.4	-0.2	1.2	-0.6	2.3
Ever taken oral contraceptive pill	1.1	1.3	4.8	-1.0	-2.2	0.4	-0.8	0.8	1.6	0.5	0.1
Hearing aid user	0.7	0.8	2.7	-1.5	-0.9	-1.7	-0.5	-0.5	0.1	0.5	-0.3
Mother’s age at death	0.3	0.4	1.2	0.1	0.4	-1.1	-0.3	-0.5	0.1	0.7	-1.0
Financial situation satisfaction	0.4	0.5	1.6	-0.9	-0.7	-0.1	0.5	1.3	-0.4	0.7	-0.8
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.3	-0.1	-0.7	-1.1	-0.3	-0.9	-0.9	-0.8	-0.9
Commuting to job workplace: Public transport	0.8	0.9	1.9	-1.4	-1.4	0.7	0.6	-0.5	-0.8	-1.3	-0.4
Eye problems/disorders: Glaucoma	0.6	0.7	2.9	0.3	1.7	-0.5	-1.0	-0.5	0.6	-0.1	-0.6
Medication: Blood pressure	0.4	0.7	1.7	1.3	0.0	0.0	0.2	1.0	1.0	1.3	0.6
Pain type(s) experienced in last month: Hip pain	0.8	1.1	2.6	-0.8	0.6	0.4	0.5	1.1	1.5	1.6	1.1
Supplements: Fish oil (including cod liver oil)	1.0	1.3	3.5	-1.9	-1.1	-0.6	-1.4	0.0	-0.9	-0.4	-1.7
High cholesterol (Self-reported)	0.2	0.4	1.7	-0.1	0.7	0.7	0.6	-0.0	-1.3	-0.2	-0.1
Medication: Bendroflumethiazide	0.5	0.7	2.2	0.7	-0.4	-0.7	1.5	-1.1	-0.3	-0.8	0.7
Medication: Paracetamol	0.4	0.6	1.4	0.6	0.7	-1.0	-1.2	-0.3	-0.6	0.3	-1.0
Medication: Lisinopril	0.7	1.0	1.8	0.5	0.5	-1.1	-1.4	-1.4	-1.1	-0.6	-0.8
Medication: Atorvastatin	0.4	0.6	2.2	-0.2	-0.3	0.6	-0.2	0.1	1.5	0.2	1.3
Illnesses of father: High blood pressure	0.8	1.0	4.3	-0.5	0.2	-0.1	-0.9	-1.4	-0.5	-2.1	0.5
Alcohol drinker status: Never	0.3	0.3	1.4	0.4	-0.0	-0.0	0.6	1.2	0.4	0.4	0.5
Ever smoked	1.2	2.2	9.8	-3.1	-1.4	-1.5	-0.6	-0.1	-0.5	0.8	-1.5
Basal metabolic rate	0.6	3.3	7.1	-0.5	2.7	-1.8	-1.7	-0.9	-2.3	-0.8	-2.5
Leg fat percentage (left)	0.8	2.7	7.7	-0.1	2.8	-1.9	-1.3	0.1	-1.6	0.3	-2.5
Arm fat-free mass (left)	0.7	3.6	7.8	-0.4	2.8	-2.5	-1.7	-1.0	-2.0	-0.3	-2.6
Number of operations (self-reported)	1.6	2.4	7.7	-0.8	0.7	1.5	-0.4	1.4	2.8	1.0	2.1
Average weekly beer plus cider intake	1.0	1.4	3.3	-0.8	0.3	-1.3	-1.0	1.4	0.1	1.8	-1.7
Irritability	1.0	1.6	7.5	-2.7	-1.4	-0.7	-0.5	-0.8	-0.6	-0.6	-1.2
Risk taking	1.8	2.6	4.9	-1.8	-1.8	0.3	-1.6	2.2	0.6	2.1	-1.5
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.1	0.2	0.6	-0.5	-0.4	-1.5	0.6	-0.3	0.5
Fractured/broken bones in last 5 years	1.7	2.1	6.5	-2.5	-2.5	-1.1	-1.0	0.2	0.2	1.0	-1.1
Age started oral contraceptive pill	0.5	0.6	1.7	0.4	0.2	-0.7	-0.2	-1.2	1.3	-0.2	1.1
Diastolic blood pressure, automated reading	0.2	0.6	2.6	1.1	1.6	-0.0	1.1	-0.1	0.2	0.1	0.0
Ever depressed for a whole week	0.1	0.1	0.5	-0.5	-0.0	0.7	-0.2	0.5	0.1	-0.3	0.0
Unable to work because of sickness or disability	0.6	0.8	2.9	-1.3	0.5	-0.6	-1.7	0.6	-0.2	0.8	-0.2
Commuting to job workplace: Cycle	0.2	0.2	0.8	-0.2	-0.4	0.9	0.3	0.5	0.2	0.2	0.3
Myopia	1.3	1.8	6.0	-0.9	-1.7	-1.2	-2.5	0.9	0.4	1.2	-1.0
Vascular/heart problems diagnosed by doctor	0.2	0.7	2.9	-1.7	-1.2	0.6	0.2	0.1	0.7	-0.2	0.5
Cholesterol lowering medication	0.4	0.6	1.2	0.2	-0.3	0.3	1.1	1.1	0.3	1.1	0.9
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	3.6	-0.3	-1.4	0.5	-0.3	1.4	1.7	1.9	0.7
Pain experienced in last month	1.1	1.8	4.6	1.4	0.0	1.6	1.5	-0.4	-1.0	-2.1	1.3
Supplements: Calcium	1.1	1.2	3.4	-1.3	-0.4	-0.3	-1.8	1.3	1.0	1.3	-0.5
Basal cell carcinoma (self-reported)	1.2	1.4	3.7	-1.3	-1.0	-0.9	1.9	-1.0	-1.6	-0.0	-0.9
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.4	-0.6	0.5	0.4	-1.6	0.1	-0.1	-0.5	-0.2
Deep venous thrombosis (DVT) (self-reported)	2.9	3.8	14.7	-2.6	-3.8	-1.1	-2.3	0.3	0.7	0.9	-0.8
Heart disease (siblings)	3.9	4.8	15.6	0.2	-1.0	-1.6	1.3	-3.1	-2.7	-3.9	-0.6
Alcohol drinker status: Previous	0.9	1.0	4.8	-2.2	-0.1	-0.6	-1.1	-0.2	-0.6	0.4	-1.2
Pack years of smoking	0.3	0.5	2.7	0.6	0.4	-0.1	-1.6	0.3	0.5	0.2	-0.2
Impedance of whole body	0.6	2.9	5.8	-2.1	-2.2	2.4	1.4	1.7	0.9	0.3	1.6
Leg fat mass (left)	0.9	3.5	10.3	-0.3	3.2	-1.9	-1.5	-0.1	-2.0	-0.1	-2.7
Arm predicted mass (left)	0.7	3.4	6.5	-0.4	2.5	-2.5	-1.9	-1.3	-1.9	-0.4	-2.4