Hub : Genes

TNK2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Uterus 0.3920 0.1390 0.00850 0.009 NA 0.019 NA 0.010 2.1e-01 NA 1.3e-01 NA 2.0e-01
2 YFS Blood 0.0135 0.0073 0.01500 0.004 0.004 0.001 0.006 0.003 1.5e-02 1.2e-02 1.2e-01 0.0029 3.5e-02
3 TCGA Breast Invasive Carcinoma 0.0396 0.0186 0.00040 0.004 0.020 0.012 NA 0.004 4.7e-02 4.2e-05 1.4e-03 NA 4.1e-02
4 TCGA Lung Adenocarcinoma 0.0517 0.0243 0.00210 0.033 0.016 0.016 NA 0.023 8.1e-05 5.0e-03 5.0e-03 NA 9.4e-04
5 TCGA Ovarian Serous Cystadenocarcinoma 0.0700 0.0360 0.00210 0.026 0.019 0.002 NA 0.013 6.5e-03 1.7e-02 2.2e-01 NA 4.2e-02
6 TCGA Prostate Adenocarcinoma 0.1018 0.0365 0.00002 0.034 0.041 0.052 NA 0.049 1.5e-04 4.1e-05 3.4e-06 NA 6.4e-06
7 TCGA Thyroid Carcinoma 0.0610 0.0370 0.00550 0.003 0.031 0.020 NA 0.018 1.5e-01 4.4e-04 4.0e-03 NA 6.1e-03
8 TCGA Uterine Corpus Endometrial Carcinoma 0.5280 0.1440 0.00022 0.042 0.117 0.144 NA 0.106 2.6e-02 3.9e-04 8.3e-05 NA 7.0e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.8 2.8 6.7 -2.0 -1.6 2.6 1.2 1.7 1.4 -0.2 1.7
Bipolar Disorder or Schizophrenia 0.5 1.3 6.4 -2.5 -0.6 0.9 -1.0 1.1 0.9 -0.0 0.3
Depressed Affect (Nagel 2018) 1.4 3.0 8.5 -2.9 -0.8 -0.9 -1.4 -1.1 -1.9 -1.3 -2.3
Depression (Nagel 2018) 0.9 1.4 3.2 -1.8 0.2 0.3 -1.0 -0.3 -1.6 -1.4 -1.5
Intelligence (Savage-Jansen 2018) 0.4 1.3 4.3 -0.9 -1.9 0.7 2.1 0.7 -0.2 -0.3 0.2
Neuroticism (Nagel 2018) 1.0 2.4 5.7 -2.4 -0.9 -0.9 -0.4 -1.0 -2.3 -1.1 -2.1
Schizophrenia (2018) 0.5 1.0 3.2 -1.7 0.6 -1.0 -1.8 0.0 0.0 0.2 -0.9
Schizophrenia vs Biploar Disorder 0.5 0.6 4.4 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0
Worry (Nagel 2018) 0.6 1.3 5.0 -1.0 0.2 -0.9 0.1 -0.2 -2.2 -0.6 -1.8
Alzheimer’s Disease (in mother) 0.4 0.4 2.0 -0.0 0.1 -0.3 -0.7 0.2 -0.6 0.7 -1.4
Alzheimer’s Disease (in father) 2.3 2.5 6.0 0.1 0.4 -1.6 -2.5 -1.6 -1.9 -1.1 -1.9
Alzheimer’s Disease (including proxy) 1.1 1.6 4.7 -0.6 -0.4 -1.0 -1.9 -0.8 -1.6 -0.3 -2.2
Crohns Disease (2017) 0.3 0.7 1.5 -0.7 -0.8 0.4 1.2 1.1 0.8 0.8 -0.3
Irritable Bowel Disease (IBD) 0.6 1.5 5.4 -0.4 -0.7 1.3 2.3 1.0 1.2 -0.1 1.1
Ulcerative Colitis (UC) 0.9 1.8 7.4 -0.1 0.1 1.4 2.7 0.6 0.9 -0.8 1.7
Major Depression (MDD) 0.3 0.4 3.0 -1.7 -0.4 0.0 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.6 1.2 2.8 -0.8 0.3 -1.7 -1.1 -0.3 -1.6 0.4 -1.5
Verbal and Numeric Reasoning (VNR) 1.0 2.5 9.2 -1.2 -3.0 1.4 2.1 1.5 0.6 0.5 0.4
Breast Cancer 0.4 1.0 2.6 0.0 0.6 0.6 1.6 -1.4 -0.4 -1.1 1.1
Ovarian Cancer 0.3 0.4 1.1 -1.0 0.0 -0.3 1.0 -0.2 -1.0 0.2 -0.5
Prostate Cancer 1.5 2.2 4.7 -1.6 -0.5 2.2 0.5 1.7 1.9 0.0 1.8
Age at First Birth 0.9 1.4 4.4 0.3 -0.1 2.1 0.5 0.6 1.1 -1.2 1.8
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.7 2.4 5.9 1.5 2.4 -0.9 -2.0 0.7 0.2 1.6 -1.8
Coronary Artery Disease (CAD) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Crohns Disease (2012) 0.4 0.6 2.4 0.6 -0.7 -0.0 0.2 1.0 0.7 1.6 -0.4
Mean Putamen Volume 0.8 1.0 1.5 -1.1 -0.7 1.0 1.2 1.2 0.8 0.5 1.1
Fasting Glucose 2.1 2.5 6.4 0.4 -1.3 -1.9 -0.7 -1.9 -2.5 -1.1 -1.7
HbA1C 0.4 0.4 1.1 -1.0 -1.1 -0.1 -0.3 0.0 0.1 0.2 -1.1
HDL Cholesterol 1.6 2.6 6.6 0.7 -0.9 -1.5 1.7 -2.4 -2.6 -1.4 -0.8
LDL Cholesterol 0.8 1.3 4.3 0.2 0.4 0.7 0.4 -0.9 -2.1 -2.0 -0.6
Lupus 1.4 2.2 4.4 -1.6 -1.1 -1.9 -0.7 0.8 -1.3 1.6 -2.1
Neuroticism (2016) 2.3 3.3 4.4 -2.1 -0.7 -1.9 -2.1 -2.0 -2.0 -1.6 -1.8
Primary Biliary Cirrhosis 0.4 0.6 3.1 -0.2 0.1 0.1 0.8 -0.3 -1.0 -1.8 -0.2
Rheumatoid Arthritis 1.0 1.4 3.6 -1.4 -1.9 -1.6 -1.2 -0.6 -0.7 -0.0 -1.1
Schizophrenia (2014) 0.5 1.1 4.1 -2.0 -0.1 0.2 -1.2 0.9 1.3 0.4 0.0
Triglycerides 0.5 0.8 2.8 1.7 1.1 0.1 -1.1 0.5 0.8 0.4 -0.0
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.1 -0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0
Ulcerative Colitis 0.3 0.4 1.3 0.2 -1.0 0.2 0.8 -0.5 -0.2 -1.1 0.0
Blood Eosinophil Count 0.5 4.0 7.9 -2.6 -1.9 1.9 2.0 2.8 1.2 1.8 1.3
Blood Platelet Count 0.8 9.1 25.5 -3.3 -2.7 2.6 1.1 5.0 2.8 3.2 1.8
Blood Red Count 2.3 22.7 50.0 6.6 5.7 -1.2 7.1 -4.8 -4.5 -3.2 0.2
Blood White Count 0.7 5.5 15.1 0.5 -0.2 2.2 1.5 3.9 2.8 3.0 2.2
Heel T-Score 0.1 0.9 2.5 0.4 -0.6 0.4 -0.9 1.0 1.3 1.6 -0.5
BMI 0.6 3.3 10.0 1.3 3.2 -2.3 -1.2 -1.3 -1.3 -1.0 -2.0
Height 0.1 2.2 10.9 -3.3 -0.3 -0.1 -2.0 0.4 -0.6 -0.1 -1.6
Waist Hip Ratio (WHR) 0.4 1.7 3.4 -0.9 -1.2 1.3 0.4 1.8 1.7 1.8 0.4
Systolic Blood Pressure 0.5 2.7 6.3 2.3 -0.1 1.4 2.2 0.5 1.6 0.3 2.5
Smoking Status 0.9 2.0 4.5 -2.1 -1.9 -0.9 -0.8 1.0 0.3 1.5 -1.8
Allergy or Eczema 0.4 1.0 2.8 -0.3 -0.4 0.8 1.1 0.8 1.4 0.9 1.7
Cardiovascular Disease 0.3 0.9 3.6 0.5 1.9 1.3 0.9 0.8 -0.7 0.2 -0.0
Hypothyroidism (self reported) 0.2 0.4 1.4 0.4 -0.7 -0.4 0.2 0.9 0.4 1.2 -0.4
Respiratory disease 4.0 8.8 15.9 -4.0 -3.0 3.0 1.7 3.2 3.2 1.4 3.3
Type 2 Diabetes (T2D) (2018) 0.4 0.8 2.8 -1.5 -1.7 -0.2 -0.6 0.8 0.3 0.3 -0.2
Lung FEV1/FVC ratio 0.4 2.2 8.9 3.0 2.2 0.9 1.1 0.6 -0.6 0.7 -0.4
Lung FVC 0.9 4.8 12.3 1.5 -2.6 -3.5 -1.2 -1.8 -1.8 0.8 -3.0
Neuroticism 1.0 2.4 5.9 -1.8 -0.8 -0.8 -1.1 -1.2 -2.4 -1.8 -1.8
Chronotype (morning person) 0.3 0.7 4.7 -0.2 0.1 -0.9 2.2 -0.0 0.2 0.4 -0.3
Hair Pigment 0.1 2.3 14.7 -0.4 0.6 1.6 3.8 0.4 -0.7 -0.3 0.5
Tanning 0.3 3.5 10.8 -0.6 -1.0 -3.3 -0.9 -2.3 -2.2 0.3 -2.0
Hand grip strength (left) 0.3 0.7 2.7 1.6 1.5 0.3 -0.3 0.1 -0.8 0.2 0.2
Number of treatments/medications taken 1.1 1.9 3.8 -1.7 -1.6 0.7 -1.4 2.0 0.9 1.7 -0.1
Average weekly spirits intake 0.1 0.2 0.4 -0.1 -0.5 -0.2 0.5 -0.4 -0.5 -0.2 0.6
Sensitivity / hurt feelings 0.2 0.4 0.7 -0.6 -0.5 -0.0 0.7 -0.5 -0.8 -0.8 0.6
Frequency of depressed mood in last 2 weeks 0.6 0.8 1.7 -1.0 -0.1 0.6 -1.0 -0.2 -1.3 -1.3 -0.8
Hearing difficulty/problems: Yes 1.0 1.5 2.9 -1.7 -1.6 -1.6 -0.9 -1.4 -0.5 -0.3 -1.0
Relative age of first facial hair 0.3 0.6 2.6 -1.6 -0.3 -0.3 -0.3 0.4 1.2 0.7 -0.5
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 6.9 -2.6 -1.4 -0.3 -0.1 0.3 -0.1 -0.6 -1.0
Ever used hormone-replacement therapy (HRT) 0.2 0.3 1.8 -1.3 0.5 -0.3 -0.2 0.3 -0.4 0.2 -0.3
Ever had hysterectomy (womb removed) 1.8 2.0 4.5 -2.1 -1.1 2.0 0.4 1.3 1.1 -0.2 1.8
Systolic blood pressure, automated reading 0.4 1.2 2.7 1.5 1.1 0.4 1.2 -0.6 1.1 -0.2 1.6
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 1.2 0.5 -1.1 -1.0 -0.5 -0.3 1.1 0.1 0.9
Angina 0.7 0.9 5.4 -0.1 -0.2 -0.7 -2.3 -0.1 0.4 0.2 -1.1
Medication for hormone replacement therapy 0.3 0.3 0.8 0.1 0.9 0.3 -0.5 0.0 -0.5 -0.9 0.5
Vitamin and mineral supplements 1.0 1.3 2.9 1.2 1.2 0.4 0.6 -1.5 1.5 -0.2 1.7
Supplements: Zinc 0.8 0.9 3.3 0.3 0.5 -0.3 -1.8 0.8 0.1 1.0 -1.4
Medication: Co-codamol 0.7 0.8 4.7 -2.2 -0.4 -0.0 -0.5 0.8 0.7 0.1 0.6
Medication: Metformin 0.7 1.0 3.5 -1.9 -1.3 -0.5 -0.7 0.8 0.6 1.0 -0.4
Diabetes (father) 1.1 1.4 3.9 -0.6 -0.6 1.3 0.5 2.0 2.0 0.3 0.6
Diabetes (mother) 0.6 0.8 1.7 0.5 -1.3 -1.0 -1.3 0.2 0.8 0.9 -0.5
Severe depression (siblings) 1.2 1.3 4.5 -0.3 -1.5 -0.6 -1.3 0.5 -1.2 0.0 -2.1
Pack years adult smoking proportion 0.3 0.4 2.1 0.3 0.3 -0.0 -1.5 0.8 0.2 0.6 -0.4
Impedance of leg (right) 0.8 3.7 6.8 -2.1 -2.6 2.3 1.2 2.3 1.6 1.3 1.5
Leg fat-free mass (left) 0.6 2.9 8.3 -0.2 2.9 -1.5 -1.8 -0.8 -1.9 -0.6 -2.2
Trunk fat percentage 0.6 2.5 10.2 -0.3 3.2 -1.2 -0.8 0.1 -1.9 -0.5 -2.0
Hand grip strength (right) 0.2 0.5 1.9 1.2 1.4 0.1 -0.7 -0.2 -0.5 0.4 0.3
Townsend deprivation index at recruitment 0.4 0.6 1.6 -0.9 -0.6 -1.1 -1.3 -0.2 -0.5 -0.1 -0.8
Current tobacco smoking 1.6 2.5 5.3 -2.2 -2.0 -2.0 0.0 -0.2 -1.5 0.1 -2.3
Average weekly fortified wine intake 1.3 1.5 2.7 1.6 1.6 -1.0 -0.3 -1.7 -1.0 -1.2 -0.4
Maternal smoking around birth 0.4 0.5 2.3 1.5 0.7 -0.1 -0.8 0.0 0.3 0.3 -0.8
Fed-up feelings 0.6 1.0 2.3 -0.2 -0.4 -1.0 -0.6 -1.5 -1.3 -1.5 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 1.5 2.0 3.6 -1.4 -1.4 -0.5 -1.9 -0.4 -1.9 -1.3 -1.7
Relative age voice broke 0.3 0.5 2.0 -1.4 0.5 0.9 0.3 0.5 0.8 -0.1 -0.5
Taking other prescription medications 1.5 2.3 5.7 -2.3 -0.6 2.2 -0.3 2.4 1.0 0.7 0.9
Age when periods started (menarche) 0.4 0.9 2.5 -1.6 1.5 0.1 -0.7 0.3 0.7 0.8 0.8
Bilateral oophorectomy (both ovaries removed) 1.3 1.5 2.7 -1.3 0.6 1.6 -0.6 1.5 1.5 0.4 1.3
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 1.3 0.3 -0.1 -1.1 -0.3 -0.6 -0.8 -0.6 -0.9
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 4.1 -0.5 -1.1 0.8 -0.4 2.0 0.9 1.9 -0.4
Qualifications: CSEs or equivalent 0.6 0.8 1.9 0.1 -1.1 0.1 -0.1 1.2 0.7 1.4 -1.0
Serious illness, injury or assault to yourself 2.2 2.6 5.9 -2.4 -1.8 -0.4 -2.4 0.4 -0.4 -0.1 -2.3
High blood pressure 0.1 0.4 1.4 1.2 0.9 -0.5 -0.1 -0.0 -0.6 0.1 -0.4
Hayfever, allergic rhinitis or eczema 0.6 1.4 2.7 -0.5 -1.6 0.5 0.3 1.5 1.5 1.5 0.8
Multivitamins +/- minerals 0.9 1.1 3.4 -1.1 -0.8 -1.0 -0.3 0.9 -1.4 -0.3 -1.8
Stomach or abdominal pain in last month 2.0 2.5 7.0 -1.0 -1.7 -1.6 -1.2 1.2 1.8 2.6 0.4
Supplements: Glucosamine 0.9 1.1 2.4 -0.2 -0.3 1.3 1.4 1.5 1.3 0.7 0.6
Diverticular disease/diverticulitis (self-reported) 1.2 1.4 3.1 -1.2 -1.8 -0.8 1.0 0.1 -1.7 0.3 -1.4
Medication: Atenolol 1.1 1.4 4.8 2.2 1.4 1.5 -0.3 0.4 0.2 -0.5 1.4
Medication: Levothyroxine sodium 0.7 1.2 1.9 1.4 -0.7 1.0 1.0 1.1 1.4 0.7 1.3
Sitting height 0.3 2.0 3.2 -1.1 1.0 -1.6 -1.7 -1.4 -1.7 -0.4 -1.8
Chronic bronchitis/emphysema (father) 0.4 0.4 1.6 -0.4 -0.5 -1.3 -0.2 0.0 0.6 0.6 -0.8
High blood pressure (mother) 0.3 0.5 1.9 0.8 1.4 -0.6 -0.0 -0.9 -0.1 0.1 -0.0
Body mass index (BMI) 0.8 3.3 10.4 0.9 3.2 -2.0 -1.2 -0.5 -1.7 -0.4 -2.5
Impedance of leg (left) 0.5 2.3 7.1 -1.9 -2.7 1.3 1.1 1.7 0.7 1.0 0.7
Leg predicted mass (left) 0.6 3.0 8.9 -0.3 3.0 -1.5 -1.9 -0.8 -1.9 -0.7 -2.1
Trunk fat mass 0.8 3.3 12.5 -0.5 3.5 -1.4 -1.3 -0.0 -2.1 -0.4 -2.4
Waist circumference 0.4 1.6 5.6 0.0 2.4 -1.2 -0.8 0.4 -1.1 0.0 -1.9
Number of incorrect matches in round 0.1 0.2 0.5 -0.4 0.5 0.5 0.1 0.1 0.5 0.7 0.4
Past tobacco smoking 0.9 1.7 4.4 2.1 1.6 1.2 1.4 -0.3 -0.2 -1.1 1.5
Alcohol usually taken with meals 0.3 0.4 0.8 -0.7 0.4 0.6 0.7 -0.9 -0.3 -0.3 0.9
Nervous feelings 0.4 0.8 3.5 -0.6 -0.6 -0.9 -0.2 -0.9 -1.9 -0.7 -0.3
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 2.6 -1.3 -1.0 -0.2 -1.6 0.6 -0.4 0.4 -1.2
Hearing difficulty/problems with background noise 0.8 1.2 3.3 -1.6 -1.8 -1.6 0.1 -1.0 -0.4 -0.1 -0.4
Hair/balding pattern: Pattern 2 0.6 0.8 2.6 1.1 0.5 0.8 1.6 0.9 0.2 0.4 0.7
Had menopause 1.0 1.3 3.1 -0.7 -0.0 0.2 1.8 0.8 1.5 1.5 1.1
Had other major operations 0.5 0.6 1.1 -1.1 -1.0 -0.7 -0.1 1.0 0.7 0.8 -0.4
Forced vital capacity (FVC) 0.3 1.3 3.9 0.4 -0.4 -1.5 0.1 -1.4 -2.0 -0.3 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 3.2 0.0 -0.0 -1.8 -0.6 -1.5 -0.2 -0.5 -0.2
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 1.4 -1.1 -0.7 0.1 -1.2 -0.5 -0.5 -0.9 -0.3
Qualifications: None of the above 0.5 1.2 5.5 -0.5 0.2 -1.1 -2.4 -0.3 1.4 0.2 -0.1
Financial difficulties in last 2 years 4.2 5.7 15.8 -1.1 -1.5 -2.8 -3.1 -1.1 -2.7 -0.3 -4.0
Mouth/teeth dental problems 2.2 3.3 6.7 2.6 2.4 0.1 2.1 -2.0 -0.9 -1.9 1.0
Heart attack 0.4 0.5 3.0 -0.5 0.4 0.0 -1.7 0.1 -0.2 -0.1 -0.5
Allergy 2.0 4.6 12.3 2.8 3.5 -0.7 1.6 -2.0 -2.5 -1.7 -0.7
Pain all over the body in last month 1.3 1.4 2.4 -1.4 -1.4 -1.5 -1.5 -0.8 -0.2 -0.9 -0.9
Diabetes (self-reported) 0.5 0.7 1.7 -1.3 -1.3 0.3 -0.4 -0.1 0.9 -0.6 0.8
Hayfever/allergic rhinitis (self-reported) 0.4 0.5 1.0 -0.1 0.0 0.9 -0.4 0.8 1.0 0.9 0.6
Medication: Ramipril 1.5 1.9 7.7 0.5 2.8 0.7 -0.1 -0.5 1.1 -1.0 2.1
Medication: Simvastatin 0.5 0.8 4.5 0.1 0.5 -0.2 0.2 0.3 -2.1 -0.2 -1.2
Fluid intelligence score 0.8 1.6 7.3 -1.0 -2.7 0.8 0.9 0.9 1.0 0.7 0.6
Illnesses of siblings 1.6 2.3 5.1 -1.3 0.3 0.2 -2.3 1.7 1.9 2.3 -0.1
Neuroticism score 0.9 1.9 4.4 -2.1 -1.3 -0.4 -0.6 -1.2 -2.0 -1.4 -1.1
Weight 0.7 3.6 10.8 -0.3 3.3 -1.9 -1.4 -0.4 -2.3 -0.5 -2.6
Impedance of arm (right) 0.8 3.6 8.6 -2.4 -1.6 2.9 2.3 1.1 0.1 -1.1 2.0
Arm fat percentage (right) 0.6 2.5 10.2 0.1 3.2 -0.8 -0.5 -0.3 -2.2 -1.1 -1.7
Trunk fat-free mass 0.4 2.2 4.0 -0.8 1.9 -1.4 -1.3 -1.1 -2.0 -1.0 -1.9
Hip circumference 0.8 3.6 8.5 -0.3 2.9 -2.0 -0.9 -0.7 -2.6 -1.0 -2.6
Time employed in main current job 0.8 0.9 2.0 -1.0 0.1 1.2 -0.7 1.4 1.3 0.9 0.2
Alcohol intake versus 10 years previously 0.3 0.4 1.2 0.2 0.5 0.8 0.5 0.5 -1.1 -0.4 -0.6
Father’s age at death 0.5 0.6 2.9 -0.6 -0.6 0.6 0.4 -0.8 -0.4 -1.7 0.1
Worrier / anxious feelings 0.4 0.7 2.0 -1.1 -1.3 -0.2 1.4 -0.3 -0.4 -0.1 0.9
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.4 3.0 -1.7 -1.6 -0.0 -1.4 1.1 1.1 0.9 0.4
Falls in the last year 1.4 1.8 5.0 -2.2 -2.1 -1.3 -0.4 -1.3 -0.7 -0.8 -1.0
Hair/balding pattern: Pattern 3 0.2 0.4 1.0 1.0 -0.6 -0.4 0.4 -0.4 -1.0 -0.2 0.2
Number of live births 0.7 1.0 3.2 1.0 0.6 0.9 0.9 -0.6 0.3 -1.2 1.8
Forced expiratory volume in 1-second (FEV1) 0.5 1.7 5.8 1.3 0.3 -1.3 -0.1 -1.4 -2.4 -0.3 -1.6
Pulse rate 0.9 1.5 6.9 2.6 0.4 1.4 0.5 1.4 0.2 0.2 0.8
Happiness 0.4 0.5 1.1 -0.8 -1.0 0.3 0.8 1.1 0.1 0.8 -0.5
Noisy workplace 0.3 0.3 1.5 -1.2 0.8 0.0 -0.2 0.1 0.3 0.4 0.5
Qualifications: A levels/AS levels or equivalent 0.5 1.2 5.0 -0.8 -0.5 0.1 0.5 -1.5 -0.8 -2.2 0.6
Serious illness, injury or assault of a close relative in last 2 years 1.4 1.6 3.4 -1.1 -1.4 1.9 1.6 0.6 -0.5 -1.7 0.5
Mouth/teeth dental problems: Dentures 1.8 3.0 7.3 -2.6 -2.1 -0.5 -2.7 0.7 1.7 1.0 -1.1
Asthma 3.1 6.1 13.9 -3.7 -3.3 2.2 0.7 2.2 2.8 0.8 2.3
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.8 0.3 -0.9 -0.7 -1.3 -0.5 0.3 0.2 -0.5
Medication: Cholesterol lowering 0.6 0.9 2.7 0.3 0.6 -0.1 -1.0 -0.8 -1.6 -1.4 -0.7
Depression (self-reported) 0.8 0.9 3.0 -1.7 -0.1 1.4 -0.2 0.1 -1.1 -1.1 0.2
Medication: Lansoprazole 0.2 0.2 0.6 -0.8 0.1 -0.2 -0.5 -0.6 -0.1 -0.7 0.5
Prospective memory result 1.7 2.0 5.5 2.0 1.6 0.4 0.4 -0.9 1.2 -1.2 2.4
Lung cancer (father) 0.6 0.7 1.4 1.2 1.2 -0.2 -0.7 -1.1 -0.1 -0.7 0.6
Illnesses of mother 0.8 1.0 2.4 -1.6 -0.8 0.9 1.2 1.0 -1.1 -0.8 -0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 2.1 1.2 0.0 -1.1 -0.2 -1.2 -1.4 0.1 -1.0
Pulse wave Arterial Stiffness index 2.4 2.8 8.2 -0.1 -1.0 2.0 2.4 1.0 1.4 -0.9 2.9
Impedance of arm (left) 0.7 3.4 9.5 -2.1 -1.7 3.1 1.8 1.3 0.6 -0.6 2.1
Arm fat mass (right) 0.8 3.1 11.3 -0.5 3.4 -1.3 -1.1 -0.2 -2.1 -0.7 -2.4
Trunk predicted mass 0.4 2.2 3.9 -0.8 2.0 -1.3 -1.3 -1.1 -2.0 -1.0 -1.8
Standing height 0.1 1.1 7.2 -2.7 0.6 0.6 -0.1 0.4 -0.8 -0.3 0.2
Length of working week for main job 0.1 0.1 0.4 -0.4 0.0 -0.2 -0.4 -0.1 -0.2 0.6 -0.3
Exposure to tobacco smoke at home 0.9 1.0 3.6 0.4 -1.1 -0.6 0.4 1.4 -0.3 1.9 -0.7
Breastfed as a baby 0.6 0.7 3.1 -1.8 -0.1 0.9 0.7 1.2 0.0 -0.1 -0.4
Tense / ‘highly strung’ 0.7 1.1 3.1 -1.8 -1.4 0.3 -0.9 1.1 -0.7 1.0 -0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 1.0 2.7 -1.3 -1.6 -0.1 -1.3 1.0 0.1 0.4 -0.9
Hair/balding pattern: Pattern 4 1.1 2.6 5.1 -2.0 0.1 2.2 -0.2 2.2 2.3 0.6 1.4
Birth weight of first child 1.3 2.4 4.0 -2.0 -0.9 1.3 -0.9 1.9 2.0 1.4 1.4
Peak expiratory flow (PEF) 1.2 2.7 8.5 0.6 -1.1 -1.3 -1.0 -2.0 -2.9 -0.9 -2.0
Pulse wave reflection index 1.8 2.3 4.5 -1.2 -1.2 1.6 2.0 1.6 1.1 0.2 2.1
Ever highly irritable/argumentative for 2 days 1.2 1.4 3.9 -1.8 -1.0 -0.5 -1.1 0.9 -0.7 0.6 -2.0
Loud music exposure frequency 0.7 0.8 2.2 0.8 -0.0 0.3 0.9 0.9 -1.2 0.6 -1.5
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 3.1 -0.2 -1.7 -0.1 1.8 0.3 -1.1 0.1 -0.1
Mouth/teeth dental problems: Bleeding gums 1.3 1.6 5.9 -2.4 -2.1 0.1 -0.8 1.0 0.0 0.9 -0.6
Blood clot in the leg (DVT) 3.3 4.3 16.2 -2.6 -4.0 -1.4 -2.7 0.0 0.6 0.7 -1.0
Medication: Paracetamol 0.3 0.5 0.9 0.6 0.3 -1.0 -0.9 -0.5 -0.7 -0.1 -1.0
Headache pain in last month 0.2 0.4 1.4 -1.2 -0.4 0.3 0.1 -0.6 0.4 -0.5 0.8
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 1.4 -0.6 -1.1 0.3 1.2 0.7 1.1 1.0 0.5
Glaucoma (self-reported) 0.4 0.5 1.8 0.7 1.3 0.6 0.2 -0.1 1.0 -0.3 0.1
Gout (self-reported) 2.9 4.0 10.7 0.0 -1.2 2.3 0.6 2.2 3.3 1.1 2.9
Hypothyroidism/myxoedema (self-reported) 0.8 1.5 4.2 0.7 0.0 0.2 0.4 1.8 1.9 2.1 0.5
Medication: Amlodipine 0.9 1.2 2.8 1.3 0.7 0.7 0.1 1.7 1.3 1.0 1.3
Medication: Ventolin 100micrograms inhaler 0.9 1.2 3.2 -0.6 -0.8 0.6 -0.5 1.8 1.2 1.8 0.4
Birth weight 0.3 0.6 2.7 -0.4 -0.3 -1.6 0.5 -1.1 -0.6 -0.0 0.5
Chronic bronchitis/emphysema (mother) 1.1 1.2 4.1 1.4 0.8 0.0 -0.1 1.5 0.9 2.0 -0.2
High blood pressure (siblings) 2.8 4.0 8.6 1.9 2.1 1.0 2.2 -2.2 -2.0 -2.9 1.1
Forced vital capacity (FVC), Best measure 0.3 1.1 2.7 0.1 -0.9 -1.5 -0.1 -1.6 -1.4 -0.2 -0.9
Body fat percentage 0.7 2.6 10.0 -0.2 3.2 -1.3 -0.9 0.2 -1.9 -0.2 -2.1
Leg fat percentage (right) 0.6 2.1 7.8 -0.3 2.8 -1.2 -1.2 0.5 -1.1 0.5 -2.1
Arm fat-free mass (right) 0.7 3.4 7.0 -0.2 2.6 -2.1 -2.1 -0.9 -1.8 -0.2 -2.6
Exposure to tobacco smoke outside home 0.9 1.1 4.9 -2.2 -0.8 -1.6 0.4 -0.6 -0.4 0.1 -0.4
Comparative body size at age 10 1.8 4.9 9.1 3.0 2.2 -1.1 -2.1 -2.0 -2.3 -2.1 -2.5
Number of full brothers 0.7 0.8 2.3 -1.5 -0.3 1.3 -0.4 1.4 0.8 -0.1 0.1
Worry too long after embarrassment 0.2 0.4 1.0 -0.6 -1.0 0.2 0.1 -0.9 -0.4 -0.9 -0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 2.4 3.2 12.2 -1.6 0.5 0.8 -0.4 -1.4 -2.8 -3.5 0.1
Wheeze or whistling in the chest in last year 0.5 0.9 3.4 -1.9 -0.8 0.5 -0.1 0.8 1.2 0.2 0.8
Number of children fathered 0.1 0.2 0.4 0.1 -0.3 0.3 0.2 -0.6 0.2 -0.5 0.6
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.7 5.9 -0.5 -0.7 1.0 2.4 -0.8 -0.6 -1.9 1.1
Age at first live birth 1.0 1.8 4.4 1.4 0.1 2.1 1.3 0.7 1.6 -0.4 1.7
Pulse wave peak to peak time 2.2 2.6 7.2 0.1 1.1 -1.8 -2.3 -1.0 -1.5 0.7 -2.7
Health satisfaction 0.9 1.1 3.8 -1.0 0.1 1.9 0.9 1.7 0.4 0.2 0.6
Shortness of breath walking on level ground 0.3 0.3 1.0 0.1 0.7 -0.6 0.4 -0.3 -1.0 -0.6 -0.2
Qualifications: College or University degree 0.4 1.1 4.0 -0.3 -0.5 0.9 1.6 -0.8 -0.6 -2.0 0.6
Eye problems/disorders: None of the above 1.3 1.5 5.1 -0.7 -1.1 -1.3 0.0 -1.0 -2.3 -1.1 -1.3
Mouth/teeth dental problems: Loose teeth 0.7 0.8 2.5 0.7 0.1 -0.7 -1.0 1.2 0.4 1.6 -0.8
Emphysema/chronic bronchitis 0.4 0.5 2.1 -1.5 0.5 0.6 -0.1 0.9 -0.3 -0.1 -0.5
Medication for pain relief, constipation, heartburn 0.6 1.0 2.5 0.9 1.5 1.0 1.6 -0.4 -0.5 -0.7 0.8
Neck or shoulder pain in last month 2.1 3.0 9.3 -3.1 -2.5 -0.9 -1.3 1.1 0.4 1.6 -1.4
Medication: Blood pressure 0.5 0.8 3.0 1.0 1.7 -0.1 -0.6 -0.7 -0.3 -1.2 0.4
Angina (self-reported) 0.5 0.7 4.1 -0.1 -0.1 -0.6 -2.0 -0.4 0.3 -0.3 -0.8
Migraine (self-reported) 0.6 0.8 1.5 -1.0 -0.4 -1.2 -0.1 -1.2 -1.1 -0.2 -0.9
Medication: Ibuprofen 0.4 0.5 1.7 1.3 0.1 -0.6 -1.1 -0.4 0.4 0.6 -0.2
Medication: Allopurinol 2.0 2.7 8.6 -0.0 0.0 2.4 -0.2 1.8 2.9 0.9 1.8
Medication: Omeprazole 0.7 0.8 1.8 -0.3 -1.2 0.4 0.7 1.2 1.0 1.3 0.6
Medication: Seretide 50 evohaler 1.4 1.7 5.0 -2.2 -1.0 -0.2 0.2 0.8 -0.5 1.7 -1.8
Mean time to correctly identify matches 0.4 0.7 1.9 -1.2 0.6 -1.0 -1.4 0.0 -0.5 0.5 -0.8
Heart disease (mother) 0.5 0.7 3.3 0.3 0.1 0.6 0.2 -0.1 1.8 0.4 1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.9 1.1 4.3 0.3 -1.6 -0.2 -0.4 0.5 -1.0 0.1 -2.1
Whole body fat mass 0.9 3.9 12.6 -0.5 3.5 -1.7 -1.5 -0.0 -2.2 -0.3 -2.8
Leg fat mass (right) 0.8 3.0 10.8 -0.4 3.3 -1.5 -1.6 0.2 -1.7 0.1 -2.4
Arm predicted mass (right) 0.6 3.1 8.0 -0.4 2.2 -2.1 -2.2 -0.5 -1.5 0.2 -2.8
Pulse rate, automated reading 0.2 0.6 2.7 0.3 0.6 -0.7 -1.6 0.4 0.0 0.8 -0.6
Alcohol intake frequency. 0.6 1.3 7.0 1.1 2.6 0.0 -0.1 1.0 -0.9 0.3 -0.4
Comparative height size at age 10 0.5 2.7 9.5 -0.2 1.4 -0.9 -0.4 -1.9 -3.1 -1.8 -1.5
Number of full sisters 0.8 1.0 2.8 0.6 -1.6 -1.3 -0.5 0.1 0.5 1.7 -0.7
Suffer from ‘nerves’ 0.7 1.1 3.2 -0.8 -0.5 -1.5 -0.5 -0.5 -1.8 -0.3 -1.4
Overall health rating 1.8 3.8 10.7 -2.5 -0.7 1.0 -1.0 3.3 1.3 3.1 -0.0
Chest pain or discomfort 1.4 2.1 5.2 -1.9 -0.6 0.4 -2.3 1.7 0.4 1.8 -1.0
Had major operations 1.0 1.1 2.8 -0.3 1.7 -0.1 0.3 -1.7 -1.0 -1.5 0.3
Age at last live birth 2.0 2.8 7.9 0.8 0.6 2.8 1.0 1.3 2.2 -0.0 2.5
Family relationship satisfaction 0.2 0.3 0.7 -0.1 0.6 -0.8 0.1 0.2 -0.6 0.5 -0.6
Leg pain on walking 0.8 1.0 3.1 -0.6 0.6 0.6 0.7 1.6 0.8 1.8 0.3
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.8 0.3 0.8 -0.9 -0.1 -0.3 -0.1 0.4 -0.2
Commuting to job workplace: Car/motor vehicle 0.5 0.5 1.7 0.7 0.6 0.1 -0.4 1.1 0.3 1.3 0.4
Illness, injury, bereavement, stress in last 2 years 3.8 4.6 15.4 2.5 1.6 1.4 2.3 0.2 2.2 0.5 3.9
Medication: Aspirin 0.6 0.8 2.3 -0.2 0.1 1.5 -0.1 0.5 0.7 -1.1 1.3
Supplements: Vitamin C 0.8 1.0 4.2 -0.8 0.0 0.0 -1.1 -0.0 -2.0 -0.5 -1.2
Knee pain experienced in last month 0.3 0.4 2.3 -0.4 1.5 0.2 0.5 0.4 -0.2 0.2 -0.7
Hypertension (Self-reported) 0.1 0.4 0.9 0.9 0.9 -0.6 -0.3 -0.2 -0.8 -0.0 -0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 4.4 -0.8 -0.5 0.7 2.1 1.1 -0.4 0.7 0.3
Illnesses of father: Heart disease 1.1 1.6 4.3 2.0 0.4 0.2 0.9 -1.0 -1.5 -2.1 0.1
Illnesses of siblings: Diabetes 0.4 0.5 1.8 0.7 -1.3 -0.7 -1.0 0.3 -0.1 0.5 -0.5
Smoking status: Previous 0.6 1.0 2.5 -1.1 -0.6 -0.1 -1.3 0.9 1.0 1.6 -0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.9 3.8 -0.8 -0.2 -0.2 -0.0 -1.4 -0.9 -1.9 0.5
Whole body fat-free mass 0.5 3.0 6.3 -0.4 2.5 -1.8 -1.7 -1.1 -2.1 -0.8 -2.2
Leg fat-free mass (right) 0.6 3.3 8.2 -0.1 2.9 -1.8 -1.8 -0.9 -2.2 -0.7 -2.3
Arm fat percentage (left) 0.6 2.2 9.8 0.1 3.1 -0.6 -0.7 -0.0 -1.9 -0.8 -1.7
Average weekly red wine intake 1.4 2.0 4.4 -2.0 -0.5 0.8 1.6 -1.4 -2.1 -1.6 0.3
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.7 0.0 0.6 0.2 0.3 0.8 -0.1 0.7 -0.3
Mood swings 1.0 1.8 5.5 -2.3 -1.9 -0.6 -0.6 0.2 -0.8 1.1 -1.6
Loneliness, isolation 2.1 2.9 8.1 -1.7 -1.6 0.2 -2.0 -1.0 -1.6 -2.9 -1.5
Long-standing illness, disability or infirmity 4.0 6.1 14.4 -3.3 -1.4 2.6 -0.6 3.8 2.9 2.1 1.2
Ever had bowel cancer screening 1.2 1.4 3.2 -0.3 -0.2 -0.1 1.5 0.9 1.8 1.8 1.2
Diabetes diagnosed by doctor 0.7 1.1 2.8 -1.1 -1.7 0.2 -0.1 0.9 1.5 0.5 1.1
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.1 -1.0 -0.5 -0.2 -0.5 -0.4 0.8 -0.6 0.2
Friendships satisfaction 0.9 1.2 3.0 1.7 0.1 -0.6 1.7 0.6 -1.2 0.9 -0.9
Qualifications: nursing, teaching 0.5 0.8 2.2 -1.0 -1.0 1.5 -0.5 0.9 0.7 0.1 0.8
Commuting to job workplace: Walk 0.6 0.6 2.4 -0.4 -1.6 0.4 1.2 0.3 -0.6 -0.8 0.0
Eye problems/disorders: Cataract 1.2 1.4 3.1 1.0 0.6 1.8 0.9 1.0 1.3 0.7 1.7
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 1.9 -0.9 -1.4 -1.0 0.2 0.9 -0.9 1.1 -1.0
Medication for cholesterol 0.3 0.4 1.7 0.2 -0.0 0.0 0.1 -1.2 -0.1 -1.3 -0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 1.3 0.0 -0.4 -1.0 -0.6 -1.2 0.3 -0.3 0.3
Back pain experienced in last month 0.8 1.1 3.2 -0.8 0.5 0.6 0.5 1.7 1.1 1.8 -0.3
Mineral and other dietary supplements 0.6 0.8 1.8 1.4 1.1 -0.4 0.4 -1.3 -0.6 -0.8 0.3
Breast cancer (self-reported) 0.5 0.5 1.7 -1.3 1.0 -0.9 -0.8 -0.4 0.0 -0.3 -0.4
Asthma (self-reported) 3.2 6.4 13.8 -3.7 -3.6 2.1 0.6 2.5 2.8 1.0 2.3
Osteoporosis (self-reported) 0.5 0.6 1.8 -0.2 0.1 0.5 1.2 -0.3 1.1 0.1 1.3
Osteoarthritis (self-reported) 0.6 0.8 2.8 0.7 1.2 0.2 -0.4 1.0 1.7 0.7 0.2
Medication: Aspirin 0.4 0.6 2.0 -0.4 0.3 1.4 -0.2 0.5 0.5 -1.1 0.8
Medication: Gliclazide 0.5 0.5 1.8 -0.0 0.5 -1.3 -0.9 -0.0 0.7 1.0 0.1
Illnesses of father: None of the above (group 1) 0.7 0.8 4.7 -0.2 -0.0 0.3 0.0 1.1 0.7 2.2 0.1
Smoking status: Current 1.8 2.8 6.0 -2.2 -2.1 -2.1 0.0 -0.3 -1.7 -0.2 -2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.8 1.6 5.0 1.8 0.2 -2.2 0.6 -1.7 -0.6 0.2 -1.1
Whole body water mass 0.5 2.8 6.6 -0.3 2.6 -1.7 -1.6 -1.1 -2.0 -0.9 -2.1
Leg predicted mass (right) 0.6 3.1 8.1 -0.1 2.8 -1.7 -1.8 -0.9 -2.1 -0.8 -2.2
Arm fat mass (left) 0.7 2.8 10.5 -0.4 3.2 -1.2 -0.9 -0.2 -2.0 -0.8 -2.2
Number of self-reported non-cancer illnesses 1.5 2.6 7.6 -1.7 -1.4 1.1 -0.5 2.8 1.5 2.2 0.3
Average weekly champagne plus white wine intake 0.7 0.9 2.8 0.2 -0.4 -1.0 1.7 -1.4 -0.6 -0.9 -0.2
Miserableness 1.6 2.7 4.9 -1.8 -0.8 -2.0 -1.7 -1.7 -1.6 -0.9 -2.2
Guilty feelings 0.3 0.4 1.1 -0.8 -1.0 0.4 -1.1 -0.2 0.1 -0.7 -0.2
Wears glasses or contact lenses 1.5 1.7 5.3 1.5 1.2 0.9 1.4 -0.2 1.2 -0.6 2.3
Ever taken oral contraceptive pill 1.1 1.3 4.8 -1.0 -2.2 0.4 -0.8 0.8 1.6 0.5 0.1
Hearing aid user 0.7 0.8 2.7 -1.5 -0.9 -1.7 -0.5 -0.5 0.1 0.5 -0.3
Mother’s age at death 0.3 0.4 1.2 0.1 0.4 -1.1 -0.3 -0.5 0.1 0.7 -1.0
Financial situation satisfaction 0.4 0.5 1.6 -0.9 -0.7 -0.1 0.5 1.3 -0.4 0.7 -0.8
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.3 -0.1 -0.7 -1.1 -0.3 -0.9 -0.9 -0.8 -0.9
Commuting to job workplace: Public transport 0.8 0.9 1.9 -1.4 -1.4 0.7 0.6 -0.5 -0.8 -1.3 -0.4
Eye problems/disorders: Glaucoma 0.6 0.7 2.9 0.3 1.7 -0.5 -1.0 -0.5 0.6 -0.1 -0.6
Medication: Blood pressure 0.4 0.7 1.7 1.3 0.0 0.0 0.2 1.0 1.0 1.3 0.6
Pain type(s) experienced in last month: Hip pain 0.8 1.1 2.6 -0.8 0.6 0.4 0.5 1.1 1.5 1.6 1.1
Supplements: Fish oil (including cod liver oil) 1.0 1.3 3.5 -1.9 -1.1 -0.6 -1.4 0.0 -0.9 -0.4 -1.7
High cholesterol (Self-reported) 0.2 0.4 1.7 -0.1 0.7 0.7 0.6 -0.0 -1.3 -0.2 -0.1
Medication: Bendroflumethiazide 0.5 0.7 2.2 0.7 -0.4 -0.7 1.5 -1.1 -0.3 -0.8 0.7
Medication: Paracetamol 0.4 0.6 1.4 0.6 0.7 -1.0 -1.2 -0.3 -0.6 0.3 -1.0
Medication: Lisinopril 0.7 1.0 1.8 0.5 0.5 -1.1 -1.4 -1.4 -1.1 -0.6 -0.8
Medication: Atorvastatin 0.4 0.6 2.2 -0.2 -0.3 0.6 -0.2 0.1 1.5 0.2 1.3
Illnesses of father: High blood pressure 0.8 1.0 4.3 -0.5 0.2 -0.1 -0.9 -1.4 -0.5 -2.1 0.5
Alcohol drinker status: Never 0.3 0.3 1.4 0.4 -0.0 -0.0 0.6 1.2 0.4 0.4 0.5
Ever smoked 1.2 2.2 9.8 -3.1 -1.4 -1.5 -0.6 -0.1 -0.5 0.8 -1.5
Basal metabolic rate 0.6 3.3 7.1 -0.5 2.7 -1.8 -1.7 -0.9 -2.3 -0.8 -2.5
Leg fat percentage (left) 0.8 2.7 7.7 -0.1 2.8 -1.9 -1.3 0.1 -1.6 0.3 -2.5
Arm fat-free mass (left) 0.7 3.6 7.8 -0.4 2.8 -2.5 -1.7 -1.0 -2.0 -0.3 -2.6
Number of operations (self-reported) 1.6 2.4 7.7 -0.8 0.7 1.5 -0.4 1.4 2.8 1.0 2.1
Average weekly beer plus cider intake 1.0 1.4 3.3 -0.8 0.3 -1.3 -1.0 1.4 0.1 1.8 -1.7
Irritability 1.0 1.6 7.5 -2.7 -1.4 -0.7 -0.5 -0.8 -0.6 -0.6 -1.2
Risk taking 1.8 2.6 4.9 -1.8 -1.8 0.3 -1.6 2.2 0.6 2.1 -1.5
Ever had prostate specific antigen (PSA) test 0.4 0.5 2.1 0.2 0.6 -0.5 -0.4 -1.5 0.6 -0.3 0.5
Fractured/broken bones in last 5 years 1.7 2.1 6.5 -2.5 -2.5 -1.1 -1.0 0.2 0.2 1.0 -1.1
Age started oral contraceptive pill 0.5 0.6 1.7 0.4 0.2 -0.7 -0.2 -1.2 1.3 -0.2 1.1
Diastolic blood pressure, automated reading 0.2 0.6 2.6 1.1 1.6 -0.0 1.1 -0.1 0.2 0.1 0.0
Ever depressed for a whole week 0.1 0.1 0.5 -0.5 -0.0 0.7 -0.2 0.5 0.1 -0.3 0.0
Unable to work because of sickness or disability 0.6 0.8 2.9 -1.3 0.5 -0.6 -1.7 0.6 -0.2 0.8 -0.2
Commuting to job workplace: Cycle 0.2 0.2 0.8 -0.2 -0.4 0.9 0.3 0.5 0.2 0.2 0.3
Myopia 1.3 1.8 6.0 -0.9 -1.7 -1.2 -2.5 0.9 0.4 1.2 -1.0
Vascular/heart problems diagnosed by doctor 0.2 0.7 2.9 -1.7 -1.2 0.6 0.2 0.1 0.7 -0.2 0.5
Cholesterol lowering medication 0.4 0.6 1.2 0.2 -0.3 0.3 1.1 1.1 0.3 1.1 0.9
Medication: Omeprazole (e.g. Zanprol) 1.1 1.4 3.6 -0.3 -1.4 0.5 -0.3 1.4 1.7 1.9 0.7
Pain experienced in last month 1.1 1.8 4.6 1.4 0.0 1.6 1.5 -0.4 -1.0 -2.1 1.3
Supplements: Calcium 1.1 1.2 3.4 -1.3 -0.4 -0.3 -1.8 1.3 1.0 1.3 -0.5
Basal cell carcinoma (self-reported) 1.2 1.4 3.7 -1.3 -1.0 -0.9 1.9 -1.0 -1.6 -0.0 -0.9
Heart attack/myocardial infarction (self-reported) 0.3 0.4 2.4 -0.6 0.5 0.4 -1.6 0.1 -0.1 -0.5 -0.2
Deep venous thrombosis (DVT) (self-reported) 2.9 3.8 14.7 -2.6 -3.8 -1.1 -2.3 0.3 0.7 0.9 -0.8
Heart disease (siblings) 3.9 4.8 15.6 0.2 -1.0 -1.6 1.3 -3.1 -2.7 -3.9 -0.6
Alcohol drinker status: Previous 0.9 1.0 4.8 -2.2 -0.1 -0.6 -1.1 -0.2 -0.6 0.4 -1.2
Pack years of smoking 0.3 0.5 2.7 0.6 0.4 -0.1 -1.6 0.3 0.5 0.2 -0.2
Impedance of whole body 0.6 2.9 5.8 -2.1 -2.2 2.4 1.4 1.7 0.9 0.3 1.6
Leg fat mass (left) 0.9 3.5 10.3 -0.3 3.2 -1.9 -1.5 -0.1 -2.0 -0.1 -2.7
Arm predicted mass (left) 0.7 3.4 6.5 -0.4 2.5 -2.5 -1.9 -1.3 -1.9 -0.4 -2.4