TWAS hub - TNNI3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.354	0.0937	0.00093	0.065	NA	0.025	NA	0.099	2.4e-03	NA	4.3e-02	NA	2.0e-04
2	GTEx	Muscle Skeletal	0.149	0.0395	0.00013	0.060	NA	0.061	NA	0.073	1.7e-06	NA	1.2e-06	NA	1.3e-07
3	TCGA	Rectum Adenocarcinoma	0.186	0.0910	0.00800	-0.008	-0.004	0.023	NA	0.014	5.3e-01	0.4	9.6e-02	NA	1.5e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Prospective memory result	4.4	5.4	9.0	-2.7	-3.0
Time employed in main current job	4.1	4.7	7.4	2.6	2.7
Leg pain on walking	4.1	5.1	8.5	2.9	2.6
Blood Platelet Count	3.6	42.2	65.8	-8.1	-7.8
Health satisfaction	3.6	4.7	8.4	2.9	2.4
Chest pain or discomfort	3.5	5.0	8.1	2.9	2.6
Gout (self-reported)	3.3	4.6	7.2	-2.7	-2.6
Pulse rate	3.1	5.2	9.6	3.1	2.4
Eye problems/disorders: Diabetes related eye disease	2.9	3.2	5.6	2.4	2.0
Vitamin and mineral supplements	2.9	3.9	6.0	-2.4	-2.5
Mouth/teeth dental problems: Loose teeth	2.9	3.4	5.8	-2.1	-2.4
Multivitamins +/- minerals	2.8	3.6	5.8	2.4	2.2
Mouth/teeth dental problems: Bleeding gums	2.7	3.5	5.6	-2.4	-2.2
Medication: Allopurinol	2.6	3.5	6.4	-2.5	-2.0
Myopia	2.6	3.8	6.4	2.5	2.2
Number of full brothers	2.5	3.2	5.2	-2.3	-2.1
Number of children fathered	2.4	2.7	4.5	-1.9	-2.1
Commuting to job workplace: Car/motor vehicle	2.4	2.8	4.5	-2.1	-2.0
Medication: Ramipril	2.3	3.0	6.1	2.5	1.7
Breast Cancer	2.2	5.3	9.4	-2.6	-3.1
Waist circumference	2.2	8.0	14.8	3.9	3.0
Average weekly champagne plus white wine intake	2.2	3.0	5.3	1.9	2.3
LDL Cholesterol	2.1	3.3	5.4	-2.1	-2.3
Waist Hip Ratio (WHR)	2.1	9.6	15.8	4.0	3.6
Lupus	1.9	2.9	5.3	2.3	1.8
Comparative body size at age 10	1.8	4.9	8.5	2.5	2.9
Leg fat percentage (right)	1.7	6.2	10.5	3.2	2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	3.5	-1.6	-1.9
Eye problems/disorders: None of the above	1.6	1.9	4.2	-2.1	-1.2
Leg fat mass (right)	1.6	6.1	10.6	3.3	2.8
Illnesses of father: None of the above (group 1)	1.6	2.0	3.3	-1.6	-1.8
Allergy or Eczema	1.5	3.8	6.4	2.3	2.5
Medication: Co-codamol	1.5	1.8	3.0	1.7	1.5
Leg fat percentage (left)	1.5	5.6	10.0	3.2	2.6
Reaction Time	1.4	2.6	3.9	-2.0	-2.0
Diabetes (mother)	1.4	1.8	4.0	-1.2	-2.0
Hayfever, allergic rhinitis or eczema	1.4	3.1	5.5	1.9	2.4
Supplements: Glucosamine	1.4	1.9	3.6	-1.4	-1.9
Father’s age at death	1.4	1.9	2.9	-1.7	-1.7
Pulse rate, automated reading	1.4	4.4	8.7	3.0	2.1
Supplements: Vitamin C	1.4	1.7	2.9	1.7	1.4
Handedness (chirality/laterality): Left-handed	1.4	1.7	3.1	-1.7	-1.4
Risk taking	1.4	2.0	3.2	1.7	1.8
Schizophrenia (2018)	1.3	2.6	4.2	1.9	2.0
Body fat percentage	1.3	5.3	10.0	3.2	2.4
Whole body fat mass	1.3	5.5	10.3	3.2	2.5
Alcohol drinker status: Previous	1.3	1.5	2.6	1.4	1.6
Leg fat mass (left)	1.3	5.3	9.7	3.1	2.5
Financial difficulties in last 2 years	1.2	1.6	3.1	-1.8	-1.2
Falls in the last year	1.2	1.6	3.1	1.8	1.3
Ever had bowel cancer screening	1.2	1.4	2.8	1.7	1.1
Trunk fat percentage	1.1	4.4	9.1	3.0	2.1
Current tobacco smoking	1.1	1.8	4.2	2.1	1.1
Trunk fat mass	1.1	4.9	9.8	3.1	2.2
Ever unenthusiastic/disinterested for a whole week	1.1	1.3	2.2	1.5	1.3
Qualifications: None of the above	1.1	2.3	4.3	-1.6	-2.1
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.4	2.2	1.5	1.4
Smoking status: Current	1.1	1.7	3.8	2.0	1.1
Schizophrenia (2014)	1.0	2.1	3.6	1.9	1.6
Townsend deprivation index at recruitment	1.0	1.4	2.7	1.3	1.6
Serious illness, injury or assault to yourself	1.0	1.3	3.0	1.7	0.9
Arm fat percentage (right)	1.0	4.0	6.8	2.6	2.2
Lung cancer (father)	1.0	1.2	2.4	1.6	1.1
Mean time to correctly identify matches	1.0	1.9	3.1	-1.6	-1.8
Arm fat percentage (left)	1.0	3.8	6.9	2.6	2.1
High cholesterol (Self-reported)	1.0	1.8	3.3	-1.4	-1.8
Blood White Count	0.9	7.0	11.1	3.3	3.2
Average weekly spirits intake	0.9	1.1	1.7	1.3	1.3
Medication: Metformin	0.9	1.2	3.2	1.8	0.7
Body mass index (BMI)	0.9	3.9	6.7	2.6	2.2
Pain all over the body in last month	0.9	1.0	2.4	-1.6	-0.7
Arm fat mass (right)	0.9	3.5	6.4	2.5	2.0
Tense / ‘highly strung’	0.9	1.5	2.5	1.4	1.6
Had major operations	0.9	1.0	2.1	1.5	1.0
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.2	1.5	1.0
Medication: Omeprazole	0.8	0.9	1.6	1.1	1.2
Alcohol intake frequency.	0.8	2.0	3.2	1.8	1.6
Osteoporosis (self-reported)	0.8	0.9	1.4	-1.2	-1.2
Arm fat mass (left)	0.8	3.3	6.2	2.5	1.9
Ever depressed for a whole week	0.8	1.0	1.6	1.2	1.3
Alzheimer’s Disease (in father)	0.7	0.8	1.3	1.0	1.1
Stomach or abdominal pain in last month	0.7	0.9	1.8	1.4	0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	2.5	1.4	1.6
Illnesses of mother	0.7	0.9	2.5	-1.6	-0.4
Length of working week for main job	0.7	0.7	1.1	1.0	1.0
Average weekly red wine intake	0.7	1.0	1.9	-1.4	-1.1
Friendships satisfaction	0.7	0.8	1.8	0.8	1.3
Breast cancer (self-reported)	0.7	0.8	1.4	-1.2	-1.0
Medication: Paracetamol	0.7	1.0	2.6	1.6	0.7
Bipolar Disorder or Schizophrenia	0.6	1.6	4.7	0.0	2.2
Alzheimer’s Disease (including proxy)	0.6	0.9	1.5	1.0	1.2
Age at First Birth	0.6	0.8	2.1	-1.4	-0.6
Blood Red Count	0.6	5.4	9.2	3.0	2.6
Respiratory disease	0.6	1.4	2.6	-1.3	-1.6
Sensitivity / hurt feelings	0.6	1.0	1.6	1.2	1.2
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.7	1.3	0.8
Ever had hysterectomy (womb removed)	0.6	0.7	1.6	-0.7	-1.3
Systolic blood pressure, automated reading	0.6	1.9	4.6	2.2	1.0
Diabetes (father)	0.6	0.7	1.4	0.9	1.2
Pack years adult smoking proportion	0.6	1.0	2.7	1.6	0.5
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	1.0	1.0	1.0
Weight	0.6	3.1	6.3	2.5	1.8
Blood clot in the leg (DVT)	0.6	0.7	1.8	-0.6	-1.3
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.4	-0.9	-1.2
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.9	1.4	0.6
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.3	0.9	1.2
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.0	-0.6	-1.4
Pack years of smoking	0.6	0.9	2.5	1.6	0.5
Rheumatoid Arthritis	0.5	0.7	1.1	1.0	1.0
Chronotype (morning person)	0.5	1.3	2.6	1.1	1.6
Hand grip strength (right)	0.5	1.4	2.5	-1.6	-1.4
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.3	1.1	0.7
Alcohol usually taken with meals	0.5	0.8	1.3	1.1	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.7	0.9	1.3
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.3	0.8	1.1
Asthma	0.5	1.0	1.9	-1.1	-1.4
Age at first live birth	0.5	0.9	2.8	-1.7	-0.2
Overall health rating	0.5	1.0	3.0	1.7	0.2
Asthma (self-reported)	0.5	0.9	1.8	-1.0	-1.3
Hearing aid user	0.5	0.6	1.1	1.1	0.7
Medication: Atorvastatin	0.5	0.6	1.0	-1.0	-1.0
Age started oral contraceptive pill	0.5	0.6	0.9	1.0	1.0
Diastolic blood pressure, automated reading	0.5	1.6	4.1	2.0	0.9
Pain experienced in last month	0.5	0.8	1.7	0.8	1.3
Alzheimer’s Disease (in mother)	0.4	0.5	0.9	0.7	1.0
Fasting Glucose	0.4	0.5	1.1	0.5	1.1
BMI	0.4	2.2	4.0	1.7	2.0
Qualifications: CSEs or equivalent	0.4	0.6	1.2	-0.7	-1.1
Allergy	0.4	0.9	1.4	-1.1	-1.2
Medication: Cholesterol lowering	0.4	0.6	1.4	-0.6	-1.2
Pulse wave Arterial Stiffness index	0.4	0.5	1.0	1.0	0.6
Breastfed as a baby	0.4	0.4	0.9	0.9	0.7
Birth weight of first child	0.4	0.8	1.7	-1.3	-0.8
Peak expiratory flow (PEF)	0.4	1.0	1.6	-1.1	-1.3
Pulse wave peak to peak time	0.4	0.5	0.9	-1.0	-0.7
Emphysema/chronic bronchitis	0.4	0.4	0.7	0.7	0.8
Migraine (self-reported)	0.4	0.5	0.9	-0.9	-0.8
Smoking status: Previous	0.4	0.6	1.0	-1.0	-0.8
Diabetes diagnosed by doctor	0.4	0.7	2.1	1.4	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.5	-1.2	-1.2
Medication: Bendroflumethiazide	0.4	0.6	1.4	1.2	0.6
Depression (Nagel 2018)	0.3	0.4	0.7	-0.8	-0.9
Worry (Nagel 2018)	0.3	0.6	1.2	1.1	0.8
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.4	1.2	0.2
Maternal smoking around birth	0.3	0.5	1.2	0.4	1.1
Hearing difficulty/problems with background noise	0.3	0.6	1.1	-1.1	-0.7
Had other major operations	0.3	0.4	0.8	-0.9	-0.5
Forced vital capacity (FVC)	0.3	1.1	2.1	-1.1	-1.5
Mouth/teeth dental problems	0.3	0.5	0.9	0.8	0.9
Hip circumference	0.3	1.5	3.3	1.8	1.1
Happiness	0.3	0.4	0.6	0.8	0.7
Hair/balding pattern: Pattern 4	0.3	0.8	1.3	-1.1	-1.0
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.8	0.9	0.3
Shortness of breath walking on level ground	0.3	0.4	1.1	1.0	0.4
Qualifications: College or University degree	0.3	0.8	2.2	0.5	1.5
Medication: Blood pressure	0.3	0.6	1.5	0.6	1.2
Medication: Aspirin	0.3	0.4	1.0	-0.3	-1.0
Illnesses of father: Heart disease	0.3	0.4	0.8	0.9	0.5
Vascular/heart problems diagnosed by doctor	0.3	0.9	1.8	-1.4	-0.9
Cholesterol lowering medication	0.3	0.4	1.1	-0.2	-1.0
Depressed Affect (Nagel 2018)	0.2	0.4	0.7	-0.7	-0.8
Crohns Disease (2017)	0.2	0.5	1.4	-0.5	-1.2
Irritable Bowel Disease (IBD)	0.2	0.4	1.3	0.1	-1.1
Mean Putamen Volume	0.2	0.2	0.5	-0.7	-0.3
HDL Cholesterol	0.2	0.3	0.5	-0.7	-0.7
Number of treatments/medications taken	0.2	0.3	1.0	1.0	0.1
Relative age of first facial hair	0.2	0.3	0.9	0.4	0.9
Supplements: Zinc	0.2	0.2	0.5	-0.5	-0.7
Leg fat-free mass (left)	0.2	1.2	2.6	1.6	1.0
High blood pressure	0.2	0.4	0.9	1.0	0.6
Medication: Atenolol	0.2	0.3	0.9	0.2	0.9
High blood pressure (mother)	0.2	0.3	1.0	1.0	0.1
Leg predicted mass (left)	0.2	1.1	2.4	1.6	0.9
Had menopause	0.2	0.2	0.7	0.2	-0.8
Diabetes (self-reported)	0.2	0.3	0.9	1.0	-0.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	1.4	-1.2	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.3	-0.8	-1.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.5	0.5	0.7
Pulse wave reflection index	0.2	0.3	0.5	-0.7	-0.6
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.7	-0.9	-0.2
Glaucoma (self-reported)	0.2	0.3	0.7	-0.3	-0.8
Birth weight	0.2	0.5	1.0	0.8	1.0
High blood pressure (siblings)	0.2	0.3	0.7	0.8	0.6
Forced vital capacity (FVC), Best measure	0.2	0.8	1.8	-0.7	-1.4
Medication for pain relief, constipation, heartburn	0.2	0.3	0.9	-0.0	1.0
Medication: Seretide 50 evohaler	0.2	0.2	0.6	0.7	0.3
Comparative height size at age 10	0.2	0.9	2.1	1.5	0.8
Number of full sisters	0.2	0.2	0.5	-0.7	-0.4
Suffer from ‘nerves’	0.2	0.4	0.6	0.7	0.7
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.5	-0.5	-0.7
Long-standing illness, disability or infirmity	0.2	0.4	1.1	1.1	0.1
Qualifications: nursing, teaching	0.2	0.3	0.7	0.8	0.5
Commuting to job workplace: Walk	0.2	0.2	0.5	-0.7	0.2
Medication for cholesterol	0.2	0.3	0.9	-1.0	-0.3
Back pain experienced in last month	0.2	0.3	0.6	0.8	-0.6
Number of self-reported non-cancer illnesses	0.2	0.3	0.6	0.8	-0.4
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.5	0.4	0.7
Medication: Blood pressure	0.2	0.4	1.1	1.0	0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.4	0.7	-0.5
Basal metabolic rate	0.2	1.2	2.5	1.6	1.0
Commuting to job workplace: Cycle	0.2	0.2	0.4	-0.6	-0.4
Heart disease (siblings)	0.2	0.2	0.6	-0.7	-0.2
Bipolar Disorder (2018)	0.1	0.1	0.3	0.0	0.5
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.5	-0.7	0.0
Ulcerative Colitis (UC)	0.1	0.3	0.8	-0.0	-0.9
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.4	-0.6	-0.1
Prostate Cancer	0.1	0.2	0.4	-0.7	-0.4
HbA1C	0.1	0.1	0.2	0.5	0.1
Triglycerides	0.1	0.1	0.2	-0.2	-0.5
Cardiovascular Disease	0.1	0.5	0.9	-0.7	-1.0
Hypothyroidism (self reported)	0.1	0.2	0.5	-0.7	-0.4
Fed-up feelings	0.1	0.1	0.2	0.5	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	-0.5	0.1
Taking other prescription medications	0.1	0.2	0.5	-0.4	-0.7
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.3	-0.5	-0.5
Medication: Levothyroxine sodium	0.1	0.1	0.4	0.6	-0.0
Past tobacco smoking	0.1	0.3	0.4	0.6	0.6
Nervous feelings	0.1	0.2	0.4	0.6	0.5
Hair/balding pattern: Pattern 2	0.1	0.1	0.3	-0.3	0.6
Heart attack	0.1	0.1	0.2	0.5	-0.1
Medication: Simvastatin	0.1	0.2	0.6	-0.1	-0.8
Fluid intelligence score	0.1	0.3	0.7	0.2	0.8
Neuroticism score	0.1	0.2	0.3	0.5	0.5
Trunk fat-free mass	0.1	0.6	1.2	1.1	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.5	0.7	0.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.4	0.6	0.4
Noisy workplace	0.1	0.1	0.3	-0.2	-0.5
Qualifications: A levels/AS levels or equivalent	0.1	0.1	0.3	-0.3	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	-0.4	-0.1
Mouth/teeth dental problems: Dentures	0.1	0.2	0.5	0.2	-0.7
Depression (self-reported)	0.1	0.1	0.1	0.3	0.4
Impedance of arm (left)	0.1	0.4	0.8	-0.6	-0.9
Trunk predicted mass	0.1	0.6	1.3	1.1	0.8
Loud music exposure frequency	0.1	0.1	0.1	-0.3	-0.4
Medication: Paracetamol	0.1	0.2	0.7	0.8	0.0
Headache pain in last month	0.1	0.2	0.6	-0.3	-0.8
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.3	-0.5	-0.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.2	-0.4	-0.5
Medication: Amlodipine	0.1	0.1	0.2	-0.3	0.4
Arm fat-free mass (right)	0.1	0.4	1.1	1.1	0.5
Exposure to tobacco smoke outside home	0.1	0.1	0.2	0.1	-0.5
Worry too long after embarrassment	0.1	0.1	0.3	0.1	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.4	-0.3	-0.6
Wheeze or whistling in the chest in last year	0.1	0.1	0.3	0.6	0.2
Neck or shoulder pain in last month	0.1	0.1	0.3	0.5	0.3
Medication: Ibuprofen	0.1	0.1	0.2	0.2	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	-0.2	-0.5
Arm predicted mass (right)	0.1	0.3	0.8	0.9	0.1
Age at last live birth	0.1	0.1	0.3	-0.6	0.2
Knee pain experienced in last month	0.1	0.2	0.3	-0.4	-0.6
Hypertension (Self-reported)	0.1	0.2	0.5	0.7	0.2
Illnesses of siblings: Diabetes	0.1	0.1	0.4	0.2	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.4	0.3	-0.6
Whole body fat-free mass	0.1	0.7	1.6	1.3	0.8
Leg fat-free mass (right)	0.1	0.7	1.6	1.3	0.6
Eye problems/disorders: Cataract	0.1	0.1	0.4	-0.1	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.3	0.1	0.6
Mineral and other dietary supplements	0.1	0.1	0.2	-0.3	0.5
Osteoarthritis (self-reported)	0.1	0.1	0.2	0.5	0.4
Medication: Aspirin	0.1	0.1	0.2	0.2	-0.4
Whole body water mass	0.1	0.6	1.3	1.2	0.7
Leg predicted mass (right)	0.1	0.7	1.8	1.3	0.6
Guilty feelings	0.1	0.2	0.3	0.5	0.4
Wears glasses or contact lenses	0.1	0.1	0.2	0.5	-0.1
Ever taken oral contraceptive pill	0.1	0.1	0.4	-0.6	0.0
Mother’s age at death	0.1	0.1	0.2	0.5	0.3
Financial situation satisfaction	0.1	0.1	0.2	-0.4	0.5
Commuting to job workplace: Public transport	0.1	0.2	0.4	0.6	0.2
Illnesses of father: High blood pressure	0.1	0.2	0.5	-0.0	0.7
Ever smoked	0.1	0.2	0.4	-0.4	-0.6
Arm fat-free mass (left)	0.1	0.5	1.2	1.1	0.5
Irritability	0.1	0.1	0.4	0.2	0.6
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.2	0.5	-0.0
Fractured/broken bones in last 5 years	0.1	0.1	0.3	-0.3	-0.5
Supplements: Calcium	0.1	0.1	0.3	0.6	-0.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	0.3	0.3
Impedance of whole body	0.1	0.5	1.0	-0.6	-1.0
Neuroticism (Nagel 2018)	0.0	0.1	0.2	0.4	0.1
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	0.0	0.1	0.2	-0.1	0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	-0.1
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.0	0.0	0.1	-0.0	0.3
Primary Biliary Cirrhosis	0.0	0.0	0.0	0.0	-0.2
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.0	0.2	0.6	-0.7	-0.2
Heel T-Score	0.0	0.1	0.3	0.6	0.3
Height	0.0	0.3	0.6	0.4	-0.8
Systolic Blood Pressure	0.0	0.2	0.5	0.7	0.2
Smoking Status	0.0	0.0	0.1	0.0	-0.2
Lung FEV1/FVC ratio	0.0	0.2	0.3	0.5	0.4
Lung FVC	0.0	0.0	0.1	0.1	0.3
Neuroticism	0.0	0.0	0.0	0.1	0.1
Hair Pigment	0.0	0.5	1.3	1.1	0.4
Tanning	0.0	0.4	1.0	0.4	1.0
Hand grip strength (left)	0.0	0.1	0.2	-0.5	-0.3
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.0	-0.2	-0.1
Hearing difficulty/problems: Yes	0.0	0.0	0.1	0.2	0.3
Angina	0.0	0.0	0.0	-0.2	-0.1
Medication for hormone replacement therapy	0.0	0.0	0.0	-0.0	-0.1
Severe depression (siblings)	0.0	0.0	0.1	-0.3	0.3
Impedance of leg (right)	0.0	0.0	0.0	-0.0	-0.1
Average weekly fortified wine intake	0.0	0.0	0.0	-0.0	-0.1
Relative age voice broke	0.0	0.1	0.2	-0.4	-0.1
Age when periods started (menarche)	0.0	0.1	0.2	0.4	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.1	0.1	0.2	0.4
Sitting height	0.0	0.1	0.2	0.2	-0.4
Chronic bronchitis/emphysema (father)	0.0	0.0	0.0	0.0	-0.2
Impedance of leg (left)	0.0	0.2	0.4	-0.4	-0.6
Number of incorrect matches in round	0.0	0.0	0.0	0.1	0.1
Illnesses of siblings	0.0	0.0	0.0	0.2	0.0
Impedance of arm (right)	0.0	0.0	0.1	-0.1	-0.2
Alcohol intake versus 10 years previously	0.0	0.0	0.1	0.2	-0.0
Worrier / anxious feelings	0.0	0.1	0.2	-0.2	-0.4
Number of live births	0.0	0.0	0.0	-0.1	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.0	-0.2	-0.1
Medication: Lansoprazole	0.0	0.0	0.1	-0.2	-0.3
Standing height	0.0	0.2	0.4	0.3	-0.7
Exposure to tobacco smoke at home	0.0	0.0	0.0	0.2	0.2
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.1	0.2	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.1	0.1	-0.2	-0.4
Angina (self-reported)	0.0	0.0	0.0	0.1	0.2
Heart disease (mother)	0.0	0.0	0.1	0.3	-0.1
Family relationship satisfaction	0.0	0.0	0.1	0.2	0.3
Mood swings	0.0	0.0	0.1	-0.3	0.1
Loneliness, isolation	0.0	0.0	0.1	0.1	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	-0.1	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	-0.0	0.0
Medication: Gliclazide	0.0	0.0	0.1	-0.3	-0.2
Miserableness	0.0	0.0	0.0	-0.1	0.0
Eye problems/disorders: Glaucoma	0.0	0.1	0.1	0.3	-0.3
Medication: Lisinopril	0.0	0.1	0.2	0.1	0.4
Alcohol drinker status: Never	0.0	0.0	0.1	0.3	0.1
Number of operations (self-reported)	0.0	0.0	0.1	0.3	-0.1
Average weekly beer plus cider intake	0.0	0.1	0.1	0.2	-0.3
Unable to work because of sickness or disability	0.0	0.0	0.1	0.3	0.1
Heart attack/myocardial infarction (self-reported)	0.0	0.1	0.1	0.3	-0.3
Arm predicted mass (left)	0.0	0.3	0.7	0.9	0.1

Hub : Genes

TNNI3

Models

Trait associations