TWAS hub - TPRA1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0880	0.0300	5.5e-04	0.075	NA	0.057	NA	0.059	9.5e-07	NA	2.0e-05	NA	1.4e-05
2	GTEx	Artery Tibial	0.2186	0.0540	6.0e-07	0.069	NA	0.105	NA	0.106	4.1e-06	NA	1.4e-08	NA	1.2e-08
3	GTEx	Brain Cerebellar Hemisphere	0.5090	0.0890	9.6e-07	0.154	NA	0.086	NA	0.247	9.3e-05	NA	3.3e-03	NA	4.9e-07
4	GTEx	Brain Cerebellum	0.4440	0.0820	2.0e-07	0.350	NA	0.270	NA	0.392	3.4e-11	NA	1.3e-08	NA	1.2e-12
5	GTEx	Muscle Skeletal	0.1200	0.0336	2.6e-06	0.094	NA	0.096	NA	0.086	1.7e-09	NA	1.2e-09	NA	8.5e-09
6	GTEx	Nerve Tibial	0.1804	0.0459	2.1e-07	0.070	NA	0.035	NA	0.076	1.1e-05	NA	1.5e-03	NA	4.8e-06
7	GTEx	Ovary	0.3980	0.1080	1.2e-03	0.012	NA	0.106	NA	0.127	1.6e-01	NA	1.5e-03	NA	5.2e-04
8	GTEx	Pituitary	0.2190	0.0750	2.4e-03	0.076	NA	0.069	NA	0.069	5.9e-03	NA	8.4e-03	NA	8.5e-03
9	GTEx	Spleen	0.2440	0.0910	4.3e-03	0.016	NA	0.037	NA	0.030	1.3e-01	NA	3.9e-02	NA	5.9e-02
10	GTEx	Stomach	0.1590	0.0590	3.3e-03	0.008	NA	0.031	NA	0.012	1.3e-01	NA	1.2e-02	NA	8.7e-02
11	GTEx	Thyroid	0.0850	0.0310	1.2e-03	0.043	NA	0.039	NA	0.037	2.9e-04	NA	5.5e-04	NA	7.1e-04
12	METSIM	Adipose	0.0973	0.0245	1.6e-08	0.033	0.062	0.061	0.064	0.065	8.3e-06	1.5e-09	1.9e-09	7.6e-10	5.6e-10
13	TCGA	Breast Invasive Carcinoma	0.0258	0.0160	9.2e-04	0.021	0.014	0.017	NA	0.021	2.9e-05	5.4e-04	1.5e-04	NA	2.7e-05
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0248	0.0156	5.4e-03	0.013	0.011	0.004	NA	0.009	1.1e-02	1.7e-02	9.3e-02	NA	3.1e-02
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0622	0.0365	7.1e-03	0.021	0.024	0.016	NA	0.018	1.6e-03	8.0e-04	5.8e-03	NA	3.8e-03
16	TCGA	Brain Lower Grade Glioma	0.0605	0.0267	3.4e-09	0.075	0.074	0.052	NA	0.063	6.5e-09	8.4e-09	1.3e-06	NA	1.0e-07
17	TCGA	Prostate Adenocarcinoma	0.0366	0.0174	2.1e-05	0.063	0.044	0.026	NA	0.052	3.7e-07	2.1e-05	8.9e-04	NA	4.1e-06
18	TCGA	Rectum Adenocarcinoma	0.1910	0.1060	1.3e-03	0.080	0.167	0.171	NA	0.148	6.4e-03	1.0e-04	8.3e-05	NA	2.5e-04
19	TCGA	Testicular Germ Cell Tumors	0.2560	0.1170	2.1e-03	0.033	0.045	0.041	NA	0.026	2.4e-02	1.0e-02	1.4e-02	NA	4.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Wears glasses or contact lenses	5.4	6.3	11.5	-2.4	-3.4	-3.0	-2.9	-2.2	-2.9	-0.9	-1.7	-1.8	-2.4	-1.3	-3.0	-2.9	-2.9	-2.2	-3.0	-3.2	-2.6	-0.6
Medication: Atorvastatin	5.2	6.4	11.9	-3.2	-2.5	-2.5	-2.9	-2.1	-3.3	-1.3	-0.7	-3.4	-2.1	-0.8	-2.0	-3.2	-3.4	-2.8	-2.8	-3.2	-1.8	-1.0
Depression (Nagel 2018)	5.0	7.5	13.6	3.1	2.9	2.7	3.0	3.0	3.0	0.7	0.7	2.5	3.7	1.5	2.5	3.1	2.8	3.1	2.9	3.2	3.0	2.6
Birth weight	5.0	10.8	19.4	3.1	4.4	4.2	3.9	3.0	3.9	1.2	3.6	1.9	2.7	2.0	3.7	3.5	3.4	2.2	4.1	3.8	3.8	1.3
Guilty feelings	4.3	6.5	18.1	2.4	2.8	2.8	2.7	3.3	2.6	1.6	1.6	2.7	4.3	1.3	2.4	2.1	2.8	1.2	3.0	2.5	2.5	2.0
Diastolic blood pressure, automated reading	4.3	13.4	24.4	-4.2	-4.3	-4.5	-4.0	-3.6	-4.0	-3.1	-2.7	-2.7	-2.6	-0.1	-4.1	-4.4	-4.9	-2.9	-4.7	-4.4	-3.3	-1.3
Average weekly beer plus cider intake	4.1	6.0	9.7	-2.6	-2.4	-2.6	-2.7	-2.8	-3.1	-2.1	-1.8	-2.0	-1.5	-1.3	-2.9	-3.1	-1.8	-2.7	-2.5	-2.9	-2.8	-1.7
Rheumatoid Arthritis	3.9	5.4	8.6	2.8	1.9	2.2	2.7	2.6	2.6	2.6	1.9	2.9	1.8	1.2	2.4	2.3	2.5	2.1	2.6	2.4	2.2	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.8	4.4	8.2	-2.4	-2.1	-2.0	-2.3	-1.9	-2.2	-1.9	-0.8	-1.4	-1.4	-1.8	-1.9	-2.5	-2.9	-2.6	-2.4	-2.3	-2.1	-2.2
Nervous feelings	3.7	6.9	18.4	2.4	3.0	2.7	2.7	3.2	2.5	1.5	1.7	1.4	4.3	1.0	2.3	2.5	2.9	2.3	3.0	2.5	3.0	3.1
Frequency of unenthusiasm / disinterest in last 2 weeks	3.6	4.7	11.0	2.2	2.3	2.2	2.2	2.3	2.4	0.9	1.2	1.6	3.3	1.5	2.0	2.3	2.2	2.1	2.4	2.3	2.5	2.3
Frequency of tenseness / restlessness in last 2 weeks	3.6	5.6	8.7	2.2	2.5	2.5	2.6	2.8	2.7	-0.5	1.4	1.8	2.9	1.6	2.0	2.3	2.6	2.1	3.0	2.3	2.8	2.6
Average weekly red wine intake	3.6	5.3	14.1	2.6	1.6	1.8	2.5	3.1	2.6	0.1	1.1	3.6	1.0	1.9	1.9	2.2	1.2	2.9	1.6	2.1	2.6	3.8
Illnesses of mother	3.5	4.3	11.4	1.6	3.0	3.4	2.3	1.1	2.7	0.3	2.5	1.2	-0.4	1.4	2.6	2.3	2.0	1.2	2.5	2.7	2.0	-0.4
Mouth/teeth dental problems: Bleeding gums	3.4	4.4	9.4	2.1	2.5	2.4	2.2	1.8	2.1	1.9	1.1	1.8	1.7	1.1	3.1	2.2	2.9	1.7	2.7	2.3	2.0	0.7
Medication: Blood pressure	3.4	6.0	11.2	-2.9	-2.8	-2.6	-2.7	-2.3	-2.6	-1.1	-0.4	-1.8	-2.7	-0.1	-2.4	-3.2	-3.4	-2.8	-2.9	-3.0	-2.3	-1.3
Medication: Lisinopril	3.3	4.3	9.7	-2.4	-2.5	-2.2	-2.2	-1.6	-2.3	-0.2	-2.1	-0.6	-1.1	-0.1	-1.8	-3.0	-3.1	-2.4	-2.6	-2.7	-2.0	-0.5
Heart disease (mother)	3.2	3.9	10.6	-1.9	-2.1	-2.5	-2.4	-1.8	-2.7	-0.9	-1.1	-3.3	-1.7	-1.0	-1.9	-2.0	-2.1	-1.4	-2.3	-2.3	-1.6	-0.3
Medication: Bendroflumethiazide	3.1	4.8	8.0	-2.5	-2.5	-2.4	-2.5	-2.1	-2.7	-0.8	-2.0	-2.4	-0.9	-0.9	-1.7	-2.3	-2.8	-2.0	-2.8	-2.3	-2.2	-2.1
Major Depression (MDD)	3.0	3.6	6.9	1.7	1.5	2.0	1.9	2.2	2.1	1.2	2.6	2.2	2.4	1.8	2.1	1.5	0.9	1.4	1.7	1.8	2.3	1.9
Number of full sisters	3.0	3.7	8.8	1.3	2.3	2.5	2.1	2.2	2.1	-0.5	2.1	1.1	1.3	3.0	2.1	1.3	0.8	0.8	2.0	1.7	2.7	2.0
Medication: Aspirin	3.0	3.9	6.4	-2.4	-2.3	-2.1	-2.3	-2.2	-2.3	0.1	-0.1	-2.0	-1.4	-1.5	-1.5	-2.2	-2.5	-2.4	-2.4	-2.2	-2.0	-1.6
Worry too long after embarrassment	2.9	4.9	8.5	2.4	2.1	2.1	2.6	2.9	2.4	1.8	1.2	2.4	2.9	0.4	2.0	1.9	2.3	1.8	2.4	2.1	2.4	2.6
Forced expiratory volume in 1-second (FEV1), predicted	2.9	6.1	11.8	2.6	3.0	3.1	2.9	2.6	3.0	0.7	1.9	1.7	2.5	1.0	2.0	2.5	3.4	1.9	3.4	2.8	2.5	0.8
Neuroticism score	2.8	5.9	21.6	2.2	2.1	2.3	2.4	3.4	2.5	1.3	1.6	2.9	4.7	1.9	1.9	1.7	2.2	1.4	2.6	1.9	2.6	2.7
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.2	11.3	2.1	1.6	1.6	1.9	2.9	2.1	2.0	1.4	2.3	3.4	1.0	1.3	1.8	1.8	2.4	1.8	1.7	2.1	2.6
Glaucoma (self-reported)	2.8	3.3	6.9	1.4	2.4	2.6	1.9	1.4	1.9	0.6	1.6	0.5	2.1	-0.6	2.2	2.1	2.5	1.3	2.4	2.2	1.7	-0.3
Medication: Ramipril	2.7	3.4	5.7	-2.1	-2.0	-2.0	-2.1	-1.9	-2.3	0.4	-0.4	-2.2	-1.4	-0.7	-1.6	-2.2	-2.0	-2.2	-2.1	-2.4	-2.0	-1.2
Family relationship satisfaction	2.7	3.3	8.0	-2.5	-1.7	-1.6	-2.0	-1.4	-2.1	-0.3	0.7	-2.1	-0.2	0.0	-1.3	-2.7	-2.6	-2.8	-2.0	-2.2	-1.3	-0.5
Hypertension (Self-reported)	2.7	7.6	19.8	-3.5	-3.1	-3.0	-3.2	-2.2	-3.2	-1.2	-1.9	-2.1	-1.1	-0.1	-2.5	-3.5	-4.5	-2.7	-3.7	-3.3	-2.4	-1.5
Heart attack/myocardial infarction (self-reported)	2.7	3.5	6.9	-2.1	-2.3	-2.5	-2.3	-1.4	-2.1	-0.2	0.4	-1.6	-1.7	-1.0	-1.8	-2.1	-2.6	-1.3	-2.6	-2.1	-1.8	-0.7
Heart attack	2.6	3.3	6.4	-2.1	-2.2	-2.4	-2.3	-1.5	-2.1	-0.4	0.3	-1.6	-1.7	-1.0	-1.8	-2.1	-2.5	-1.4	-2.5	-2.1	-1.8	-0.7
Miserableness	2.6	4.4	10.5	2.0	1.5	1.9	2.1	2.6	2.4	0.6	1.1	3.2	3.2	1.6	1.6	1.7	1.4	1.6	2.1	1.9	2.3	3.0
Qualifications: College or University degree	2.5	8.0	15.8	2.8	3.0	3.3	3.2	3.4	3.3	-0.1	1.6	2.6	2.1	3.4	2.2	2.4	2.4	2.7	3.0	2.5	3.5	4.0
Lung FEV1/FVC ratio	2.4	12.1	32.8	4.0	3.9	3.6	3.7	3.5	4.6	3.4	1.4	2.5	2.5	0.0	3.5	4.2	5.7	2.6	4.6	4.1	2.0	-0.5
Medication for cholesterol, blood pressure or diabetes	2.4	4.0	9.4	2.3	2.5	2.3	2.0	1.6	2.1	0.6	0.0	0.7	1.7	-0.5	2.4	3.1	2.8	2.2	2.3	2.8	1.7	0.5
Mean Putamen Volume	2.3	2.6	7.1	-1.1	-2.2	-2.0	-1.5	-1.7	-1.6	-0.5	-2.7	-0.8	-2.0	-0.6	-1.6	-1.5	-1.9	-0.7	-2.2	-1.5	-1.7	0.1
Medication: Cholesterol lowering	2.3	3.6	9.1	-2.1	-2.4	-2.2	-1.8	-1.5	-1.9	-0.7	-0.4	-0.9	-1.5	0.1	-2.3	-3.0	-2.6	-2.2	-2.1	-2.8	-1.5	-0.8
Ever highly irritable/argumentative for 2 days	2.3	2.8	4.1	-1.8	-1.8	-1.6	-2.0	-1.3	-2.0	-1.9	-1.3	-1.6	-0.6	-1.4	-1.8	-1.9	-1.2	-2.0	-1.5	-2.0	-1.9	-1.3
Lupus	2.2	3.3	8.2	1.3	2.6	2.9	2.2	1.3	2.2	0.1	2.2	0.7	1.9	1.2	1.8	1.9	1.4	1.0	2.0	2.2	2.2	0.9
Blood Eosinophil Count	2.2	17.3	28.9	-4.5	-3.9	-3.8	-4.0	-4.5	-4.2	-5.0	-2.1	-3.9	-4.9	-1.2	-5.2	-5.0	-5.4	-4.1	-4.7	-4.7	-3.3	-1.7
Frequency of depressed mood in last 2 weeks	2.2	3.0	8.2	1.6	1.8	1.6	1.8	2.5	1.6	0.4	1.0	1.9	2.9	1.3	1.5	1.2	1.5	1.3	1.7	1.5	2.1	2.3
Mouth/teeth dental problems	2.2	3.3	6.7	-1.8	-2.2	-1.9	-2.0	-1.5	-2.1	-1.1	-0.7	-1.0	-1.5	-0.2	-2.6	-2.2	-2.2	-1.9	-2.2	-2.3	-2.0	-1.1
Mood swings	2.2	4.1	8.8	1.9	1.9	2.1	2.1	2.5	1.7	2.0	2.0	1.7	3.0	2.1	1.5	1.4	1.7	1.2	2.2	1.7	2.3	2.6
Qualifications: A levels/AS levels or equivalent	2.1	4.6	10.2	2.6	1.1	1.4	2.0	2.9	1.8	2.1	0.8	3.2	2.2	1.9	1.8	2.1	1.5	2.8	1.6	1.8	2.2	3.1
Vascular/heart problems diagnosed by doctor	2.1	5.7	16.5	3.1	2.8	2.6	2.7	1.9	2.8	0.8	1.5	1.7	0.8	-0.3	2.1	3.1	4.1	2.3	3.2	2.9	1.9	1.2
Cholesterol lowering medication	2.1	3.1	5.5	-2.0	-1.5	-1.4	-1.9	-1.8	-2.0	-0.3	-1.0	-2.2	-2.4	-1.5	-1.2	-1.8	-2.1	-1.7	-1.8	-1.7	-1.5	-2.1
Primary Biliary Cirrhosis	2.0	2.9	4.9	1.6	2.2	1.9	1.8	1.9	2.1	0.5	2.1	1.0	2.1	0.8	1.3	1.9	1.0	1.8	1.6	2.2	2.0	1.2
Cardiovascular Disease	2.0	6.5	11.3	-3.0	-2.6	-2.5	-2.9	-2.4	-3.2	-2.1	-2.4	-2.8	-1.6	-0.3	-2.8	-3.0	-3.4	-2.6	-2.8	-2.9	-2.1	-1.4
Hypothyroidism (self reported)	2.0	4.6	9.4	1.8	3.1	2.7	2.1	1.6	1.9	2.3	2.9	0.4	0.7	1.4	2.3	2.1	1.7	2.0	2.3	2.4	2.7	2.2
Birth weight of first child	2.0	3.7	8.1	1.6	2.0	2.0	2.2	2.0	2.4	1.1	1.1	1.4	1.7	1.6	2.9	2.0	1.5	1.4	2.1	2.2	2.1	1.9
Diabetes (mother)	1.9	2.4	3.4	-1.7	-1.8	-1.8	-1.8	-1.8	-1.8	-1.4	-0.5	-1.4	-0.1	-1.6	-1.6	-1.5	-1.4	-1.5	-1.7	-1.7	-1.6	-1.4
Ever depressed for a whole week	1.9	2.3	6.9	1.2	1.1	1.3	1.3	2.1	1.6	0.9	2.0	1.9	2.6	1.6	1.3	0.8	0.1	1.4	0.9	1.0	1.8	1.9
Neuroticism	1.8	4.3	12.5	1.7	1.8	2.3	2.2	2.4	2.3	1.6	1.7	2.5	3.5	2.6	1.9	1.3	1.3	1.0	2.1	1.6	2.4	2.0
Hand grip strength (left)	1.8	4.8	11.6	3.2	1.8	1.4	2.2	2.6	2.3	0.6	0.7	2.8	1.7	1.1	1.2	3.0	2.8	3.4	2.2	2.6	1.8	1.3
Loud music exposure frequency	1.8	2.0	3.9	1.7	1.6	1.9	1.7	1.3	1.5	-0.1	0.8	1.1	0.5	0.6	1.3	1.8	1.7	1.2	2.0	1.8	1.8	0.7
Medication: Aspirin	1.8	2.4	5.5	-2.1	-1.8	-1.5	-1.7	-1.8	-1.7	0.2	0.3	-1.8	-0.9	-0.6	-1.0	-1.8	-2.3	-1.9	-1.8	-1.7	-1.2	-1.3
Neuroticism (Nagel 2018)	1.7	4.1	13.7	1.6	1.9	2.3	2.1	2.5	2.1	1.6	1.4	2.3	3.7	1.7	1.8	1.4	1.4	0.9	2.0	1.7	2.2	2.3
High blood pressure	1.7	4.6	12.8	-2.8	-2.5	-2.3	-2.5	-1.6	-2.6	-0.4	-1.5	-1.5	-0.4	0.2	-1.9	-2.8	-3.6	-2.1	-2.9	-2.6	-1.8	-1.1
Tense / ‘highly strung’	1.7	2.8	6.6	1.8	1.9	1.8	1.8	2.0	1.7	-0.6	0.8	0.7	2.6	0.9	1.1	1.8	1.8	1.6	2.0	1.7	2.1	1.6
Alcohol drinker status: Never	1.7	2.1	6.5	-2.0	-0.6	-0.4	-1.3	-1.1	-1.7	0.8	0.1	-2.5	-0.3	0.1	-0.1	-1.6	-1.7	-2.5	-1.1	-1.2	-1.1	-2.5
Worry (Nagel 2018)	1.6	3.4	15.0	1.4	2.0	1.9	1.9	2.2	1.8	1.2	1.2	1.2	3.9	0.5	1.6	1.4	2.1	0.7	2.3	1.6	1.8	1.6
Breastfed as a baby	1.6	2.0	6.5	-0.6	-2.2	-2.2	-1.4	-0.6	-1.4	0.1	-2.5	0.0	-1.1	-0.4	-1.5	-1.1	-1.7	0.4	-2.0	-1.5	-1.1	0.9
Pulse wave peak to peak time	1.6	1.9	5.5	1.4	1.4	1.1	1.5	1.0	1.5	1.2	0.8	1.3	2.3	0.1	1.3	1.5	1.7	1.4	1.3	1.6	1.1	1.0
Age at last live birth	1.6	2.4	5.2	1.7	1.8	1.5	1.9	1.3	1.8	1.7	1.3	1.6	1.2	1.0	1.5	1.4	2.3	1.1	1.9	1.5	1.2	1.0
Age started oral contraceptive pill	1.6	1.9	4.8	-1.3	-1.8	-1.8	-1.4	-1.4	-1.2	-0.5	-1.9	-0.4	-1.6	0.8	-1.5	-1.1	-2.2	-0.6	-2.0	-1.4	-1.1	-0.4
Fluid intelligence score	1.5	3.0	5.1	2.0	1.5	1.8	1.9	1.7	2.0	0.7	0.7	2.3	2.2	0.9	1.5	2.1	2.3	1.8	1.8	1.9	1.4	1.5
Trunk fat-free mass	1.5	8.7	15.3	3.0	3.5	3.4	3.5	3.6	3.6	1.2	3.9	2.2	2.4	2.2	2.8	2.9	2.9	2.1	3.5	3.3	3.1	0.9
Prospective memory result	1.5	1.9	3.0	-1.3	-1.5	-1.6	-1.5	-1.7	-1.7	0.5	-1.3	-1.2	-1.2	-0.8	-1.2	-1.3	-1.4	-1.3	-1.7	-1.4	-1.6	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.5	4.7	10.9	2.5	2.3	1.7	2.3	2.5	2.4	-0.6	0.6	1.7	2.4	-0.3	1.8	2.7	3.3	2.4	2.8	2.6	2.1	1.4
Trunk predicted mass	1.5	8.6	14.8	2.9	3.6	3.4	3.5	3.5	3.5	1.2	3.8	2.1	2.5	2.1	2.8	2.9	2.9	2.1	3.5	3.3	3.1	0.9
Comparative height size at age 10	1.5	8.2	13.0	3.1	3.4	3.1	3.5	2.9	3.6	0.4	2.6	2.8	1.3	2.2	2.8	3.1	3.0	2.6	3.6	3.4	3.2	1.5
Illnesses of father: High blood pressure	1.5	1.9	5.7	-1.7	-1.1	-0.8	-1.3	-1.1	-1.5	-0.8	1.2	-1.2	-1.6	0.6	-0.8	-2.0	-2.4	-1.9	-1.4	-1.8	-0.6	-0.3
Depressed Affect (Nagel 2018)	1.4	3.0	7.8	1.4	1.4	1.9	1.6	2.1	1.8	1.2	0.8	2.7	2.8	2.6	1.4	1.2	0.8	1.1	1.5	1.4	1.8	1.9
Hearing difficulty/problems: Yes	1.4	2.2	4.5	1.4	1.7	1.6	1.6	1.7	1.7	1.5	2.1	1.0	-0.1	0.2	1.6	1.3	0.9	1.1	1.5	1.5	1.9	1.9
Systolic blood pressure, automated reading	1.4	4.0	8.6	-2.4	-2.2	-2.5	-2.2	-2.0	-2.3	-1.3	-2.1	-2.0	-0.7	0.2	-1.9	-2.2	-2.9	-1.6	-2.6	-2.1	-1.6	-1.5
Hand grip strength (right)	1.4	3.8	8.0	2.7	1.9	1.6	2.2	2.0	2.4	-0.3	0.4	2.2	0.9	1.2	1.2	2.7	2.2	2.8	2.1	2.5	1.9	1.2
Peak expiratory flow (PEF)	1.4	3.3	10.2	2.1	1.8	0.9	1.5	1.6	1.5	-2.1	-0.5	1.1	2.9	-1.7	0.7	2.3	3.2	1.9	2.0	2.0	0.9	1.1
Arm fat-free mass (right)	1.4	7.1	14.2	2.4	3.3	3.3	3.3	3.1	3.3	0.6	3.8	1.8	2.3	2.4	2.5	2.3	2.3	1.6	3.2	2.9	3.0	0.9
Medication for pain relief, constipation, heartburn	1.4	2.4	4.3	1.7	2.0	1.6	1.8	0.9	1.9	-0.6	-0.1	0.5	0.2	1.7	1.4	1.9	2.1	2.0	1.9	1.8	1.8	1.4
Arm predicted mass (left)	1.4	7.3	14.2	2.4	3.4	3.3	3.2	3.2	3.2	0.9	3.8	1.8	2.4	2.4	2.6	2.4	2.3	1.7	3.2	2.9	3.1	1.0
Age when periods started (menarche)	1.3	3.1	7.2	1.9	1.8	1.7	1.6	1.9	1.7	1.8	-0.7	0.9	1.6	0.8	2.7	2.0	2.5	1.7	2.2	1.9	1.5	1.0
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	4.8	-1.4	-0.8	-0.5	-1.1	-0.4	-1.2	-0.9	0.6	-1.8	-1.2	2.0	-1.0	-1.7	-2.2	-1.2	-1.2	-1.4	-0.1	0.3
Hypothyroidism/myxoedema (self-reported)	1.3	2.6	7.0	1.0	2.4	2.0	1.3	1.0	1.4	2.3	2.6	-0.5	0.3	0.8	2.1	1.5	0.7	1.3	1.5	1.8	2.1	1.6
Age at first live birth	1.3	2.2	5.9	1.6	1.2	1.1	1.8	1.3	1.7	1.7	0.9	2.0	1.5	1.2	1.3	1.2	2.4	1.2	1.9	1.2	1.0	1.3
Arm predicted mass (right)	1.3	6.7	13.8	2.3	3.2	3.1	3.1	3.1	3.1	0.7	3.7	1.7	2.4	2.5	2.4	2.2	2.2	1.5	3.1	2.8	2.9	0.9
Eye problems/disorders: Cataract	1.3	1.5	3.1	-1.3	-1.6	-1.3	-1.2	-1.0	-1.1	-1.6	-1.8	0.1	-0.7	0.2	-1.5	-1.3	-1.6	-0.9	-1.4	-1.5	-0.9	-0.8
Pain type(s) experienced in last month: Hip pain	1.3	1.6	4.9	1.9	1.1	0.7	1.0	1.6	0.8	0.3	-0.7	-0.1	0.8	-0.5	0.7	1.8	1.8	2.2	1.4	1.5	1.2	1.2
Arm fat-free mass (left)	1.3	6.4	12.8	2.2	3.2	3.1	3.0	3.0	3.0	0.7	3.6	1.6	2.5	2.3	2.4	2.2	2.2	1.4	3.0	2.7	2.8	0.8
Number of treatments/medications taken	1.2	2.2	8.4	-1.2	-2.1	-1.8	-1.3	-0.9	-1.6	0.7	0.4	-0.2	-1.1	1.2	-1.9	-1.9	-2.9	-0.8	-1.9	-1.9	-0.5	0.6
Ever used hormone-replacement therapy (HRT)	1.2	1.5	5.1	-0.2	-1.9	-1.8	-0.9	-0.5	-1.3	0.6	-2.3	0.7	-0.2	0.4	-1.8	-0.9	-1.3	0.6	-1.5	-1.3	-0.4	1.4
Sitting height	1.2	8.6	14.3	3.3	3.2	3.1	3.6	3.8	3.4	0.8	3.0	2.6	1.4	2.1	2.4	2.8	3.4	2.5	3.7	3.0	3.4	2.5
Allergy	1.2	2.8	5.7	1.9	2.1	1.6	1.7	2.1	1.8	1.8	0.3	1.2	1.7	0.0	2.2	1.9	2.4	1.4	1.9	2.1	1.1	0.3
Forced expiratory volume in 1-second (FEV1)	1.2	4.1	10.2	2.2	2.1	1.5	2.1	2.5	2.2	-1.1	0.0	1.3	2.6	-0.2	1.6	2.4	3.2	2.2	2.6	2.4	1.9	1.5
Medication: Allopurinol	1.2	1.6	2.5	-1.2	-1.3	-1.4	-1.4	-1.5	-1.4	-0.7	-1.2	-0.9	-0.6	-1.6	-1.5	-1.3	-1.1	-1.1	-1.4	-1.3	-1.4	-0.8
Whole body fat-free mass	1.2	7.0	15.4	2.5	3.3	3.2	3.2	3.1	3.3	1.0	3.9	1.7	2.0	2.2	2.6	2.4	2.3	1.6	3.1	2.9	2.9	0.7
Number of self-reported non-cancer illnesses	1.2	2.1	6.7	-1.8	-1.8	-1.3	-1.4	-1.2	-1.8	-0.4	-0.1	-1.1	-0.6	0.7	-1.5	-2.1	-2.6	-1.3	-1.8	-2.0	-0.5	0.8
Eye problems/disorders: Glaucoma	1.2	1.4	3.6	0.7	1.9	1.8	1.1	0.3	0.9	-0.3	0.9	-0.3	1.2	-0.9	1.5	1.5	1.9	0.8	1.6	1.5	0.9	-0.9
Respiratory disease	1.1	2.4	7.5	-1.5	-2.2	-1.9	-1.6	-1.1	-1.8	-1.9	-1.0	-0.1	-0.8	0.6	-1.6	-1.7	-2.7	-0.0	-2.1	-1.9	-0.5	1.6
Ever had hysterectomy (womb removed)	1.1	1.2	4.6	-1.2	-1.6	-0.7	-1.2	-0.4	-1.1	-0.6	-1.6	-0.9	-1.0	0.8	-0.5	-1.2	-2.1	-0.6	-1.4	-1.1	-0.5	-0.4
Supplements: Glucosamine	1.1	1.4	4.0	1.3	0.6	0.8	1.2	1.3	1.1	0.5	0.2	1.3	1.9	0.5	1.1	1.3	1.0	2.0	1.2	1.1	1.3	1.2
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	5.0	1.1	0.5	1.0	1.0	1.6	1.4	0.8	2.2	1.9	1.9	0.5	0.5	0.7	-0.1	1.0	0.4	0.8	1.1	1.1
Alcohol intake versus 10 years previously	1.1	1.6	3.6	0.9	1.7	1.9	1.4	1.6	1.4	-0.6	0.8	0.2	1.5	1.0	0.7	1.0	1.2	0.7	1.7	1.3	1.6	1.4
Happiness	1.1	1.3	4.8	0.1	0.9	1.3	0.8	1.0	1.3	0.0	1.9	0.5	1.6	2.2	1.1	0.3	-0.7	-0.3	0.6	0.7	1.6	1.4
Pulse wave Arterial Stiffness index	1.1	1.3	5.2	-1.0	-1.1	-0.9	-1.2	-0.6	-1.1	-1.2	-0.7	-0.9	-2.3	0.0	-1.1	-1.2	-1.3	-1.0	-1.0	-1.3	-0.9	-1.0
Shortness of breath walking on level ground	1.1	1.3	5.9	0.4	1.6	1.3	0.9	0.4	1.4	-0.4	2.4	-0.3	-0.3	2.1	1.4	0.9	-0.2	0.4	0.9	1.2	1.3	0.2
Osteoarthritis (self-reported)	1.1	1.4	3.2	-1.0	-1.3	-1.8	-1.3	-0.6	-1.3	-0.6	-1.5	-1.1	0.5	-1.3	-1.8	-1.1	-1.1	-0.5	-1.5	-1.4	-1.3	0.3
Whole body water mass	1.1	6.4	13.8	2.3	3.2	3.1	3.1	3.0	3.2	0.7	3.7	1.6	1.9	2.1	2.5	2.4	2.3	1.5	3.0	2.8	2.8	0.6
Mother’s age at death	1.1	1.4	8.7	-0.1	-1.1	-1.2	-0.9	-1.1	-1.0	-0.2	-2.9	-0.2	-0.7	-2.0	-1.3	-0.2	0.7	-0.0	-0.6	-0.6	-1.7	-1.3
Basal metabolic rate	1.1	6.0	16.0	2.1	3.2	3.0	2.9	2.8	3.0	1.0	4.0	1.3	1.7	2.1	2.5	2.2	1.9	1.3	2.9	2.7	2.7	0.3
Supplements: Calcium	1.1	1.2	4.4	1.1	-0.2	-0.3	0.3	1.1	0.2	2.1	-0.0	1.8	0.9	1.4	0.6	0.7	0.3	2.1	-0.1	0.3	0.8	2.0
Neuroticism (2016)	1.0	1.4	3.8	0.3	1.4	1.7	1.1	1.1	1.1	0.7	0.9	0.8	1.7	1.9	1.6	0.7	0.5	-0.3	1.4	0.9	1.6	0.9
Allergy or Eczema	1.0	2.7	6.0	-1.8	-1.9	-1.8	-1.8	-1.8	-1.7	-1.7	-0.8	-0.8	-1.8	-0.4	-1.8	-1.7	-2.5	-1.4	-2.1	-1.9	-1.4	-0.5
Relative age voice broke	1.0	1.6	4.1	-1.9	-1.0	-1.0	-1.6	-1.9	-1.6	-0.0	-0.5	-1.6	-0.4	0.2	-0.5	-1.2	-2.0	-1.3	-1.5	-1.2	-0.9	-0.9
Impedance of arm (left)	1.0	4.6	9.2	-1.9	-2.3	-2.2	-2.4	-2.9	-2.3	-0.5	-3.0	-2.3	-2.9	-2.5	-1.8	-1.5	-1.2	-1.5	-2.0	-1.9	-2.5	-1.6
Neck or shoulder pain in last month	1.0	1.4	3.1	1.5	1.1	1.0	1.3	1.2	1.8	0.3	0.8	-0.0	0.8	-0.5	0.9	1.6	1.7	1.0	1.6	1.5	1.0	0.0
Illness, injury, bereavement, stress in last 2 years	1.0	1.3	4.6	0.4	0.9	1.4	1.2	0.3	1.1	1.1	2.1	0.8	0.1	1.6	1.9	0.8	-0.7	0.8	0.5	1.1	1.4	0.6
Medication: Blood pressure	1.0	1.8	6.3	-1.5	-1.5	-1.7	-1.4	-0.6	-1.5	-0.0	-1.5	-0.6	0.4	0.9	-1.1	-1.8	-2.5	-0.8	-2.0	-1.8	-0.8	-0.2
Prostate Cancer	0.9	1.3	8.1	-0.1	1.1	0.6	0.5	0.9	0.8	2.9	0.6	0.8	1.8	1.9	1.2	-0.3	0.6	-0.8	0.6	0.1	0.5	1.4
HDL Cholesterol	0.9	1.5	3.3	1.1	1.4	1.6	1.6	1.1	1.5	0.1	0.8	1.8	1.5	1.2	1.1	0.7	0.9	0.9	1.5	1.1	1.7	0.4
Hair/balding pattern: Pattern 3	0.9	1.3	5.3	-1.2	-1.6	-1.5	-1.2	-1.1	-1.0	-0.1	0.3	0.1	-0.4	0.1	-1.5	-1.5	-2.3	-0.7	-1.7	-1.4	-0.6	-0.1
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.3	-0.9	-1.2	-1.0	-0.7	-0.7	-0.7	-1.2	-1.8	0.3	0.1	0.7	-0.6	-1.3	-1.3	-1.7	-0.9	-1.1	-0.7	-0.0
Forced vital capacity (FVC), Best measure	0.9	3.3	6.0	1.9	1.8	1.3	1.9	1.9	1.8	-1.4	0.1	1.1	2.1	0.0	1.5	2.2	2.5	2.2	2.3	2.2	2.1	2.0
Smoking status: Previous	0.9	1.3	4.2	1.5	0.7	0.7	1.1	1.6	1.3	-0.0	-0.0	1.4	1.1	-0.4	0.6	1.1	1.4	1.6	1.2	0.9	1.1	2.0
Fractured/broken bones in last 5 years	0.9	1.2	3.6	0.9	1.4	1.3	1.0	1.1	1.2	0.3	-0.0	0.7	0.7	1.2	1.9	1.4	1.0	1.2	1.1	1.4	1.2	0.4
Ulcerative Colitis (UC)	0.8	1.5	3.1	-1.6	-1.1	-1.2	-1.3	-1.8	-1.1	-1.2	-1.3	-1.3	-1.0	-0.3	-0.9	-1.3	-0.7	-1.6	-0.9	-1.2	-1.5	-1.3
Crohns Disease (2012)	0.8	1.3	2.8	-1.7	-1.0	-1.2	-1.2	-1.1	-1.3	-1.2	-0.8	-0.7	-1.1	-0.7	-0.9	-1.5	-1.5	-1.2	-1.4	-1.4	-0.8	0.6
Medication: Co-codamol	0.8	0.9	2.4	1.3	0.6	0.5	1.0	1.4	0.7	1.0	-0.3	0.8	1.6	0.2	1.0	1.2	1.0	0.8	0.9	1.1	0.8	1.0
Diabetes (father)	0.8	1.0	3.6	-1.2	0.5	0.7	-0.5	-0.2	-0.5	1.2	1.9	-1.6	-0.7	1.6	0.7	-1.0	-1.1	-1.7	-0.1	-0.6	0.3	0.1
Leg fat-free mass (left)	0.8	4.1	14.8	1.5	2.7	2.5	2.4	2.1	2.5	0.8	3.8	0.8	1.1	1.9	2.2	1.6	1.3	0.7	2.3	2.1	2.3	0.0
Taking other prescription medications	0.8	1.3	3.4	-1.3	-1.2	-1.0	-1.0	-0.8	-1.5	0.2	0.5	-1.3	-0.6	0.4	-1.4	-1.6	-1.9	-1.4	-1.2	-1.4	-0.3	1.1
Leg predicted mass (left)	0.8	4.2	15.4	1.5	2.8	2.6	2.4	2.1	2.5	0.8	3.9	0.8	1.1	1.9	2.2	1.7	1.4	0.7	2.4	2.2	2.3	0.0
Qualifications: None of the above	0.8	1.6	6.3	-1.7	-0.9	-0.7	-1.4	-1.6	-1.4	-0.4	-0.5	-2.3	-0.4	-0.2	-0.5	-1.3	-2.5	-1.1	-1.5	-0.9	-0.5	-1.4
Financial difficulties in last 2 years	0.8	1.1	3.2	-1.1	-1.0	-0.9	-1.4	-1.2	-1.3	0.8	-0.1	-1.8	0.7	-1.3	-1.0	-0.9	-0.9	-1.0	-1.1	-0.9	-1.1	-0.7
Impedance of arm (right)	0.8	3.6	6.5	-1.7	-2.2	-2.0	-2.3	-2.5	-2.1	-0.1	-2.5	-2.0	-2.4	-1.9	-1.5	-1.3	-1.2	-1.4	-1.9	-1.7	-2.2	-1.5
Father’s age at death	0.8	1.1	3.9	1.3	0.4	0.6	1.2	0.9	1.1	0.3	-0.4	2.0	0.7	-0.3	0.4	1.4	1.2	1.5	0.9	1.0	0.7	1.1
Worrier / anxious feelings	0.8	1.6	9.8	0.9	0.7	0.7	1.0	1.5	1.0	2.0	1.1	1.3	3.1	-0.6	1.0	0.7	1.0	0.2	0.9	0.8	0.8	1.5
Standing height	0.8	8.1	14.7	3.3	3.1	3.2	3.5	3.4	3.6	0.8	2.8	2.4	1.3	1.1	2.5	3.2	3.8	2.3	3.8	3.3	2.7	1.1
Wheeze or whistling in the chest in last year	0.8	1.4	4.0	-1.2	-1.3	-0.8	-0.8	-0.6	-1.2	-1.8	0.2	-1.1	-1.2	1.1	-1.1	-1.6	-2.0	-0.9	-1.0	-1.4	0.1	1.1
Mean time to correctly identify matches	0.8	1.6	5.0	-1.4	-1.0	-0.9	-1.0	-1.8	-1.0	-0.9	-0.8	-1.8	-2.0	-0.0	-1.1	-1.0	-1.1	-1.0	-0.9	-1.0	-1.0	-2.2
Chest pain or discomfort	0.8	1.2	3.6	-0.9	-0.8	-0.7	-0.7	-0.9	-1.2	-0.6	1.0	-1.9	-0.3	0.8	-1.8	-1.6	-0.8	-1.7	-0.5	-1.4	-0.4	-0.3
Leg pain on walking	0.8	1.1	4.1	0.3	1.6	1.6	0.7	0.2	0.7	-0.0	1.3	-1.2	-0.4	2.0	1.5	0.8	-0.2	-0.3	0.9	1.2	1.2	-0.4
Leg fat-free mass (right)	0.8	4.2	14.0	1.6	2.7	2.6	2.5	2.3	2.6	0.6	3.7	1.0	1.3	2.0	2.1	1.6	1.3	0.7	2.3	2.1	2.4	0.3
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.8	-0.4	-1.0	-1.1	-1.0	-0.4	-1.5	-1.4	-1.7	-1.0	-0.4	-1.6	-1.4	-0.6	0.2	-0.3	-0.5	-0.8	-1.1	-0.1
Loneliness, isolation	0.8	1.1	4.9	0.5	0.1	0.7	0.8	1.4	0.9	0.9	0.4	2.2	2.0	1.8	0.4	0.1	-0.1	0.4	0.5	0.2	1.0	1.4
Long-standing illness, disability or infirmity	0.8	1.3	4.9	-1.0	-1.4	-1.2	-1.0	-0.4	-0.9	-0.3	0.3	-0.9	-1.3	0.9	-1.3	-1.6	-2.2	-0.7	-1.4	-1.5	-0.3	0.6
Diabetes diagnosed by doctor	0.8	1.3	3.9	-1.8	-0.8	-0.3	-0.8	-0.6	-0.8	-1.4	1.2	-1.4	-0.2	0.3	-0.6	-1.6	-1.8	-2.0	-0.8	-1.1	-0.6	-1.1
Medication: Gliclazide	0.8	0.9	2.6	-1.0	-0.6	-0.1	-0.8	-0.9	-0.9	-1.6	0.5	-1.5	-1.2	-0.7	-0.6	-0.8	-1.6	-1.0	-0.7	-0.5	-0.4	-1.4
Leg predicted mass (right)	0.8	4.3	14.1	1.6	2.7	2.6	2.5	2.3	2.6	0.6	3.8	1.0	1.3	2.0	2.1	1.6	1.3	0.7	2.4	2.1	2.4	0.3
Commuting to job workplace: Cycle	0.8	1.0	2.3	-1.5	-0.5	-0.6	-1.0	-1.3	-1.0	-0.3	-0.9	-0.3	-0.1	1.3	-0.1	-1.5	-1.5	-1.0	-1.2	-1.3	-0.7	0.2
Fasting Glucose	0.7	0.8	3.8	0.5	1.0	0.9	0.8	0.7	0.7	-0.2	0.5	0.8	1.0	2.0	1.1	0.2	0.0	0.3	0.6	0.6	1.2	1.7
LDL Cholesterol	0.7	1.1	3.1	-1.3	-0.8	-0.5	-0.8	-1.3	-1.0	-0.4	-1.1	-1.8	-0.7	1.0	-1.0	-1.3	-1.7	-1.1	-1.1	-1.0	-0.3	-0.1
Systolic Blood Pressure	0.7	3.7	7.5	-2.1	-2.0	-2.2	-1.9	-1.7	-2.4	-2.0	-1.9	-2.1	-0.6	0.2	-1.6	-2.3	-2.7	-1.7	-2.3	-2.2	-1.4	-1.4
Smoking Status	0.7	1.8	6.7	0.8	1.4	1.3	1.2	1.1	1.4	-1.7	-0.2	0.6	2.6	0.2	0.4	1.1	1.4	0.9	1.4	1.1	1.3	2.3
Sensitivity / hurt feelings	0.7	1.3	4.4	0.9	0.4	0.6	0.9	1.8	0.6	1.4	1.2	1.9	1.8	1.4	0.4	0.0	0.6	0.2	0.9	0.2	1.0	2.1
Relative age of first facial hair	0.7	1.4	3.3	-1.4	-1.2	-0.8	-1.5	-1.7	-1.4	0.1	-0.3	-1.8	-1.2	-0.7	-0.3	-1.0	-1.3	-1.2	-1.2	-1.0	-1.2	-1.7
Current tobacco smoking	0.7	1.1	9.0	-1.5	0.3	0.5	-0.6	-1.1	-0.4	-3.0	-0.4	-1.7	0.7	-0.9	-0.5	-0.7	-0.5	-1.4	-0.2	-0.5	-0.2	-0.9
Asthma	0.7	1.4	5.2	-0.8	-1.8	-1.3	-0.9	-0.9	-0.9	-1.3	-0.0	0.0	-0.8	1.4	-1.0	-1.1	-2.3	0.1	-1.5	-1.2	-0.1	1.5
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	6.3	1.0	-0.1	-0.0	0.5	0.8	0.2	0.8	-0.3	1.5	0.6	0.6	-0.1	0.2	0.8	1.2	0.6	-0.0	0.7	2.5
Suffer from ‘nerves’	0.7	1.1	5.9	0.8	1.0	0.8	0.8	1.7	0.8	1.1	0.2	1.0	2.4	-0.4	1.1	0.8	1.2	0.3	1.1	0.7	0.8	0.6
Had major operations	0.7	0.8	2.5	-0.1	-1.6	-1.3	-0.7	0.1	-1.1	-0.1	-1.4	0.0	0.6	-0.7	-1.2	-0.9	0.2	-0.1	-0.3	-1.2	-1.0	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	2.2	-0.9	-0.4	-0.4	-0.9	-1.0	-1.3	-0.1	-0.3	-0.7	-1.4	-1.2	0.0	-0.8	-0.8	-1.1	-0.7	-0.9	-0.8	-1.5
Arm fat percentage (left)	0.7	2.7	9.0	-2.2	-0.4	-0.4	-1.4	-2.0	-1.1	0.5	1.3	-3.0	-2.0	0.1	-0.4	-1.5	-2.6	-2.1	-1.5	-1.1	-0.8	-2.4
Back pain experienced in last month	0.7	1.0	3.3	1.1	1.0	0.8	1.0	1.8	0.9	0.0	0.3	0.9	1.1	0.3	0.6	1.1	0.8	1.0	1.0	0.9	1.3	1.2
Asthma (self-reported)	0.7	1.3	5.2	-0.7	-1.8	-1.3	-0.8	-0.9	-0.8	-1.3	-0.0	0.1	-1.0	1.3	-1.0	-1.0	-2.3	0.1	-1.5	-1.2	-0.0	1.5
Smoking status: Current	0.7	1.1	8.6	-1.5	0.3	0.4	-0.6	-1.0	-0.4	-2.9	-0.5	-1.5	0.8	-0.9	-0.6	-0.7	-0.6	-1.2	-0.3	-0.5	-0.3	-0.7
Average weekly champagne plus white wine intake	0.7	1.0	5.0	-0.7	-1.1	-0.6	-0.9	-1.4	-0.7	-0.8	-0.2	-0.5	-2.2	-0.2	-1.2	-1.1	-1.2	-0.6	-1.1	-1.1	-0.6	0.2
High cholesterol (Self-reported)	0.7	1.2	3.5	-1.2	-0.4	-0.3	-1.0	-0.7	-1.4	-0.9	0.2	-0.9	-1.4	0.1	-0.9	-1.8	-0.8	-1.9	-0.5	-1.5	-0.7	-1.3
Pain experienced in last month	0.7	1.1	2.2	-1.1	-1.3	-1.1	-1.2	-1.5	-1.4	-1.0	-1.5	-0.0	-0.9	-0.5	-0.7	-1.1	-0.9	-0.8	-1.0	-1.1	-1.2	-1.2
Intelligence (Savage-Jansen 2018)	0.6	1.9	4.9	1.5	0.8	1.2	1.3	1.6	1.6	-0.1	-0.5	2.2	1.1	1.1	1.0	1.6	1.9	1.8	1.2	1.2	1.0	1.6
Height	0.6	11.3	18.1	4.2	3.6	3.3	4.0	4.0	4.2	1.8	3.0	2.9	2.0	0.6	2.6	4.1	4.2	3.6	4.0	4.0	3.2	1.4
Waist Hip Ratio (WHR)	0.6	2.5	7.5	1.1	2.4	2.7	1.7	0.4	1.3	1.6	1.1	-0.2	0.6	1.4	2.3	1.7	1.8	-0.4	2.2	2.1	1.2	-0.9
Average weekly spirits intake	0.6	0.7	2.8	-1.1	0.0	-0.0	-0.7	-0.9	-0.9	0.3	0.5	-0.5	0.0	1.2	-0.1	-0.9	-1.4	-1.4	-0.7	-0.7	-0.5	-1.7
High blood pressure (mother)	0.6	0.8	2.8	-0.6	-1.2	-1.2	-0.5	-0.2	-1.2	-1.1	-1.7	-1.0	1.2	-0.9	-0.8	-0.8	-0.3	-0.4	-0.3	-0.9	-0.4	0.4
Waist circumference	0.6	2.1	10.5	0.0	2.0	2.1	0.9	0.7	1.0	1.8	3.2	-1.7	-0.5	1.1	1.8	0.7	-0.1	-0.7	1.1	1.3	1.2	-1.6
Number of incorrect matches in round	0.6	1.0	3.1	-1.2	-0.8	-0.3	-0.6	-1.8	-0.9	-0.4	-0.1	-1.4	-1.1	-0.2	-0.9	-1.3	-1.4	-1.8	-0.7	-0.9	-0.6	-0.8
Alcohol usually taken with meals	0.6	1.0	5.2	0.9	0.0	0.4	0.7	1.3	0.9	0.7	-0.6	2.3	0.3	1.4	-0.1	0.4	0.1	1.2	0.2	0.3	0.7	1.9
Forced vital capacity (FVC)	0.6	2.2	4.7	1.3	1.3	1.0	1.4	1.7	1.3	-2.2	-0.3	0.6	1.9	0.3	1.1	1.6	1.8	1.6	1.7	1.6	1.7	1.9
Arm fat percentage (right)	0.6	2.5	8.4	-2.1	-0.3	-0.3	-1.4	-1.8	-1.0	0.7	1.4	-2.9	-1.9	0.3	-0.3	-1.3	-2.5	-2.0	-1.4	-1.0	-0.8	-2.4
Number of live births	0.6	0.8	2.6	0.9	1.0	1.0	1.1	0.3	1.2	-0.4	0.2	0.4	1.6	-0.4	0.8	1.4	0.6	1.2	0.8	1.2	0.9	-0.6
Noisy workplace	0.6	0.7	1.9	0.3	1.3	0.8	0.8	0.7	0.8	0.2	-0.1	0.4	1.3	0.7	1.4	0.8	0.8	0.5	0.9	0.8	1.0	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.8	-0.8	-0.7	-0.6	-0.5	-0.3	-0.7	1.4	1.5	-0.2	0.2	1.2	-0.1	-1.1	-1.7	-0.9	-1.0	-0.9	-0.1	0.9
Depression (self-reported)	0.6	0.7	1.6	-1.1	-0.8	-1.0	-1.0	-0.4	-1.2	0.3	0.5	-0.9	-0.5	-0.4	-0.8	-1.2	-1.3	-0.8	-1.1	-1.1	-0.4	0.7
Lung cancer (father)	0.6	0.7	3.4	-0.7	-0.8	-0.7	-0.9	-0.4	-1.0	-0.6	-0.2	-0.4	-0.6	-1.0	-1.0	-0.9	-0.3	-0.7	-0.4	-0.8	-1.0	-1.8
Body fat percentage	0.6	2.3	8.7	-2.1	-0.2	-0.2	-1.3	-1.8	-0.9	0.2	1.3	-3.0	-2.0	0.4	-0.4	-1.4	-2.3	-2.0	-1.2	-0.9	-0.7	-2.4
Overall health rating	0.6	1.4	5.0	-1.4	-0.2	0.0	-0.7	-0.3	-0.9	0.4	2.1	-1.8	-0.7	1.5	-0.2	-1.4	-2.2	-1.9	-0.7	-1.0	0.4	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.1	-0.9	-0.6	-0.6	-0.7	-0.7	-0.4	-0.7	0.6	-0.3	-0.1	0.6	-1.1	-1.0	-1.4	-0.9	-1.1	-1.0	-0.3	0.5
Breast cancer (self-reported)	0.6	0.7	3.6	0.9	0.9	0.8	1.1	0.8	0.7	-0.4	0.4	0.7	0.0	-0.0	0.1	0.8	1.9	0.7	1.5	0.7	0.7	0.5
Osteoporosis (self-reported)	0.6	0.8	3.5	-0.1	-1.4	-1.2	-0.5	-0.7	-0.8	1.0	-0.5	0.2	-1.9	1.0	-0.9	-0.7	-1.2	-0.0	-1.0	-0.8	-0.4	-0.5
Ever taken oral contraceptive pill	0.6	0.7	1.9	-0.7	-0.6	-0.7	-0.5	-0.5	-0.1	-1.4	1.1	1.2	0.1	0.2	-1.1	-1.0	-0.9	-0.1	-0.8	-1.1	-0.2	1.0
Impedance of whole body	0.6	3.2	8.4	-1.5	-2.0	-1.8	-2.0	-2.3	-2.0	-0.6	-2.9	-1.9	-2.1	-1.9	-1.7	-1.3	-0.8	-1.2	-1.6	-1.6	-2.1	-1.1
Irritable Bowel Disease (IBD)	0.5	1.1	3.8	-0.9	-1.2	-1.6	-1.1	-0.9	-1.0	-1.3	-1.9	-0.2	-0.6	-0.8	-1.3	-0.9	-0.2	-0.6	-0.9	-1.1	-1.3	0.4
Age at First Birth	0.5	0.8	3.2	1.0	1.0	0.9	1.1	1.0	1.0	-0.5	-0.2	1.8	0.7	0.1	0.9	0.6	0.9	0.4	0.9	0.9	0.7	0.6
Bipolar Disorder (2011)	0.5	0.5	2.0	0.7	0.9	0.9	0.0	0.6	0.7	0.0	0.0	-0.1	0.8	0.0	0.4	1.0	1.2	0.3	1.4	0.0	0.0	-0.6
Vitamin and mineral supplements	0.5	0.6	3.9	-0.6	0.0	-0.5	-0.5	-1.3	-0.5	-0.8	-0.8	-1.2	-0.4	-0.2	-0.6	-0.2	-0.2	-0.8	-0.5	-0.2	-0.9	-2.0
Supplements: Zinc	0.5	0.5	1.6	0.5	-0.9	-1.2	-0.3	0.2	-0.1	1.0	-1.2	0.2	-0.4	-1.1	-0.1	0.6	0.3	1.2	-0.6	0.1	-0.6	0.4
Trunk fat percentage	0.5	2.0	7.8	-1.9	-0.1	-0.1	-1.1	-1.6	-0.7	0.2	1.3	-2.8	-1.9	0.4	-0.4	-1.3	-2.0	-2.0	-1.0	-0.8	-0.6	-2.2
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.2	-0.6	-0.9	-1.0	-0.6	-1.1	-0.9	-0.1	-0.1	0.0	-1.0	-0.8	-1.1	-0.9	-0.8	-0.3	-0.9	-0.9	-0.6	-0.3
Serious illness, injury or assault to yourself	0.5	0.6	3.2	0.0	0.5	0.4	0.2	1.5	0.3	0.3	1.2	0.8	0.8	1.8	0.0	-0.6	-0.0	-0.0	0.4	-0.4	0.8	1.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	3.7	1.1	-0.1	-0.1	0.2	0.8	0.1	-0.6	-1.9	1.5	-0.4	-0.7	-0.3	0.5	0.0	1.4	-0.2	0.4	0.1	1.0
Chronic bronchitis/emphysema (father)	0.5	0.5	1.6	-0.6	-1.3	-0.9	-0.8	-0.4	-1.1	-0.1	-0.1	-0.4	-0.6	-0.5	-0.3	-0.8	-1.1	-0.8	-0.8	-0.8	-0.7	-0.1
Diabetes (self-reported)	0.5	0.8	3.4	-1.3	-0.1	0.2	-0.5	-0.4	-0.4	-1.4	1.3	-1.1	-0.2	0.0	-0.2	-1.0	-1.1	-1.8	-0.3	-0.7	-0.3	-1.0
Weight	0.5	2.6	12.2	0.7	2.2	2.2	1.7	1.4	1.9	0.9	3.5	-0.1	0.4	1.7	1.7	1.1	0.5	0.2	1.6	1.6	1.8	-0.6
Health satisfaction	0.5	0.6	1.9	-0.2	0.9	0.9	0.4	0.4	0.4	-1.1	1.2	-0.7	-0.4	1.4	0.7	-0.1	-1.2	-0.3	0.3	0.4	1.3	0.1
Mouth/teeth dental problems: Loose teeth	0.5	0.6	6.3	-0.0	-0.5	-0.5	-0.5	-0.1	-0.5	-0.6	-1.7	-0.3	0.1	-2.5	-0.4	-0.1	0.5	0.1	-0.1	-0.3	-0.4	0.5
Medication: Ibuprofen	0.5	0.6	3.0	-0.1	-0.5	-0.3	0.0	0.2	-0.2	1.2	0.9	0.6	0.3	1.5	0.0	-0.5	-1.4	-0.1	-0.6	-0.5	0.4	1.7
Friendships satisfaction	0.5	0.6	4.2	-0.1	0.7	1.1	0.6	0.1	0.9	0.2	2.0	0.2	0.6	0.9	1.0	0.1	-0.3	-0.2	0.5	0.5	0.9	-0.1
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.7	-0.8	-1.1	-0.7	-0.6	-0.4	-0.3	0.9	-0.7	0.2	-0.3	0.8	0.1	-0.7	-1.9	-0.5	-1.3	-0.6	-0.4	-0.2
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.5	-0.8	-1.0	-0.9	-0.7	-0.5	-0.8	-1.2	-0.5	-0.8	-0.6	-0.8	-1.2	-0.9	-0.7	-0.3	-0.5	-1.0	-0.5	0.5
Bipolar Disorder (2018)	0.4	0.6	3.1	0.4	-0.1	-0.5	-0.2	0.3	-0.3	-0.4	-1.8	0.1	1.8	-1.2	-0.8	0.3	1.1	0.4	0.1	0.1	-0.6	-0.1
Crohns Disease (2017)	0.4	0.9	2.6	-0.5	-1.0	-1.5	-1.0	-0.4	-1.1	-1.0	-1.6	0.0	-0.5	-1.3	-1.2	-0.6	-0.1	0.0	-0.9	-0.9	-1.1	0.8
Body Mass Index (BMI) (2010)	0.4	0.6	1.3	-0.6	-1.0	-0.9	-0.7	-0.8	-0.7	-0.0	0.0	-1.0	-0.4	-0.7	-1.1	-0.7	-0.5	-0.6	-0.8	-0.9	-1.0	-1.1
Lung FVC	0.4	2.0	11.2	0.9	0.5	0.3	1.0	1.6	0.8	-3.3	-1.6	0.0	0.7	-0.3	0.8	1.4	0.6	2.2	0.9	1.2	1.7	2.6
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	2.2	-0.7	0.7	0.9	-0.2	0.4	0.1	-0.7	1.2	-0.8	-0.8	1.5	0.8	-0.3	-1.4	-0.2	-0.3	-0.0	0.9	0.5
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	0.9	0.8	0.6	0.5	0.4	0.8	0.5	0.9	0.2	0.4	0.9	0.9	0.7	0.8	0.3	0.8	0.3	0.7	0.5	0.5
Angina	0.4	0.5	2.1	-0.8	-0.9	-0.9	-0.5	-0.1	-0.2	-0.8	-0.3	-0.0	-0.0	0.4	-0.3	-0.9	-1.5	0.1	-1.0	-0.8	0.0	0.9
Medication for hormone replacement therapy	0.4	0.5	2.2	0.3	0.3	0.2	0.4	0.6	0.4	-0.5	0.5	0.6	1.5	1.1	-0.6	0.0	-0.1	1.0	0.1	0.1	1.0	1.1
Severe depression (siblings)	0.4	0.4	1.6	0.8	-0.6	-0.7	-0.1	0.8	-0.2	0.8	-1.2	1.0	0.6	0.4	-0.2	0.1	0.5	0.8	-0.0	-0.2	-0.1	1.3
Multivitamins +/- minerals	0.4	0.5	3.2	0.3	0.3	0.7	0.4	1.3	0.1	0.5	0.8	0.6	0.4	0.6	0.8	-0.0	-0.2	0.5	0.5	0.1	1.1	1.8
Medication: Levothyroxine sodium	0.4	0.6	2.7	0.1	1.2	0.8	0.3	0.4	0.3	1.6	1.0	-0.9	-0.0	-0.2	1.0	0.5	0.1	0.5	0.5	0.7	1.0	1.5
Pain all over the body in last month	0.4	0.4	1.3	-0.7	-0.4	-0.9	-0.5	-0.1	-0.4	0.5	1.1	0.1	-0.9	0.4	-0.5	-0.8	-0.9	-0.4	-0.8	-0.7	-0.1	0.5
Medication: Simvastatin	0.4	0.6	1.8	-0.9	-0.2	-0.1	-0.3	-0.5	-0.3	0.9	1.0	-0.1	-1.0	0.7	-0.2	-1.3	-1.2	-1.0	-0.4	-0.9	-0.1	-1.2
Pulse rate	0.4	0.6	3.3	-0.7	0.4	0.5	-0.1	-0.9	0.1	-0.9	0.3	-1.5	-1.8	1.1	-0.3	-0.6	-0.5	-0.9	0.1	-0.3	0.2	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.1	1.3	0.5	0.1	0.3	0.9	0.3	0.7	0.0	0.2	-0.2	-0.9	-0.1	0.8	1.4	0.7	0.6	0.5	0.1	0.5
Medication: Lansoprazole	0.4	0.4	2.5	0.8	0.4	0.2	0.4	0.5	0.0	1.3	0.2	-0.2	1.6	-0.1	0.2	0.5	0.4	0.8	0.6	0.6	0.5	0.1
Blood clot in the leg (DVT)	0.4	0.5	3.2	0.1	-0.5	-0.6	-0.4	-0.1	-0.6	0.5	-1.1	-0.3	-0.2	-1.8	-0.5	0.3	0.6	0.1	-0.1	-0.2	-0.8	-1.3
High blood pressure (siblings)	0.4	0.5	3.9	0.1	0.5	0.4	0.5	0.4	-0.0	-0.1	0.4	-0.1	0.8	2.0	0.6	-0.3	-0.7	0.1	0.3	-0.0	1.3	1.2
Leg fat percentage (right)	0.4	1.5	6.3	-1.6	0.1	-0.0	-0.9	-1.4	-0.7	0.5	1.4	-2.5	-1.4	0.7	-0.1	-0.9	-1.8	-1.4	-0.9	-0.5	-0.4	-2.0
Exposure to tobacco smoke outside home	0.4	0.5	3.5	0.5	-0.4	-0.4	-0.2	1.0	-0.5	0.7	-0.4	1.2	1.0	-0.1	-0.7	-0.4	0.5	0.4	0.0	-0.5	-0.1	1.9
Number of children fathered	0.4	0.4	2.3	0.9	0.6	0.0	0.5	0.2	0.4	0.0	0.2	0.2	-0.8	-0.9	0.2	0.9	1.5	0.5	0.7	0.7	-0.1	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.8	0.9	0.4	0.2	0.6	0.9	0.6	-0.2	-0.1	0.9	0.7	-0.0	0.5	0.9	0.3	1.4	0.3	0.6	0.9	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.2	-0.3	-0.7	-0.6	-0.8	-0.4	-0.7	-0.1	-0.0	-1.1	-1.0	-0.8	-1.1	-0.4	-0.5	-0.3	-0.6	-0.4	-0.7	-0.9
Illnesses of siblings: Diabetes	0.4	0.5	2.0	0.4	0.7	1.0	0.8	0.5	0.8	1.0	1.4	-0.0	-1.0	0.5	0.8	0.4	0.0	0.3	0.7	0.7	0.9	-0.2
Illnesses of father: None of the above (group 1)	0.4	0.5	1.9	0.4	-0.2	-0.5	0.1	-0.6	0.3	1.4	-0.7	0.5	0.6	-1.4	-0.3	0.7	0.8	1.2	0.0	0.5	-0.2	-0.3
Ever smoked	0.4	0.7	5.7	0.4	0.5	0.4	0.6	0.7	0.7	-0.9	0.2	0.5	1.6	-0.0	0.3	0.4	0.6	0.9	0.5	0.4	0.9	2.4
Number of operations (self-reported)	0.4	0.7	2.6	-0.1	-1.2	-1.0	-0.8	-0.4	-1.3	-0.3	-1.2	-0.0	0.0	-0.5	-1.6	-0.8	-0.0	0.0	-0.4	-1.0	-0.7	-0.8
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.8	-0.3	0.1	0.5	0.5	-0.1	1.0	1.7	1.0	0.9	0.1	1.0	1.2	0.2	-0.6	-0.2	-0.0	0.3	0.4	-0.2
Unable to work because of sickness or disability	0.4	0.6	2.2	-0.0	0.7	0.7	0.6	0.9	0.5	-0.8	1.5	-0.4	0.6	1.0	0.5	-0.0	-0.6	0.3	0.3	0.3	1.3	1.2
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	1.5	1.0	0.6	0.4	0.4	0.8	0.6	0.1	-0.2	1.2	-0.1	-0.8	-0.3	0.8	1.1	0.7	0.8	0.6	0.3	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	1.1	-0.1	-0.2	-0.5	-0.3	0.3	0.0	-0.5	0.6	1.1	0.1	-0.8	-1.1	-0.4	-0.2	-0.2	-0.7	-0.7	-0.7	0.7
Reaction Time	0.3	0.5	2.8	-0.8	-0.3	-0.1	-0.4	-1.2	-0.4	0.1	0.2	-1.7	-1.0	0.1	-0.4	-0.5	-0.3	-0.7	-0.0	-0.4	-0.3	-1.6
HbA1C	0.3	0.3	0.9	-0.3	-0.7	-0.6	-0.2	-0.3	-0.4	0.7	-0.9	0.3	-0.6	-0.0	-0.9	-0.5	-0.6	-0.2	-0.5	-0.8	-0.2	0.3
Triglycerides	0.3	0.5	1.9	-0.5	-0.8	-0.8	-0.7	-0.6	-0.5	-0.5	-0.4	-1.2	-0.2	-1.4	-0.6	-0.4	-0.7	-0.4	-1.0	-0.4	-0.9	-0.5
Ulcerative Colitis	0.3	0.4	1.4	-1.0	-0.3	-0.5	-0.6	-0.5	-0.5	-1.0	-0.3	-1.0	-1.0	-0.0	-0.3	-0.6	0.1	-1.2	-0.1	-0.6	-0.7	-0.4
Type 2 Diabetes (T2D) (2018)	0.3	0.7	4.0	-0.8	0.2	0.9	0.1	-0.1	0.0	-0.2	2.0	-1.2	0.7	0.9	0.5	-0.3	-0.9	-1.2	0.2	0.0	0.3	-1.1
Chronotype (morning person)	0.3	0.6	3.6	-1.0	-0.8	-0.8	-0.7	-0.3	-0.5	0.3	0.3	-0.2	-1.2	0.1	-0.1	-0.9	-1.9	-0.2	-1.3	-0.8	-0.3	-0.6
Medication: Metformin	0.3	0.4	3.1	-0.3	0.4	0.9	0.3	0.4	0.4	-0.1	1.8	-0.6	-0.2	0.5	0.7	-0.0	-0.6	-0.6	0.4	0.3	0.6	-0.8
Townsend deprivation index at recruitment	0.3	0.4	2.8	0.0	0.6	0.7	0.2	0.6	0.2	0.1	1.7	-0.0	1.1	-0.7	0.4	0.1	-0.1	-0.2	0.4	0.3	0.7	0.7
Maternal smoking around birth	0.3	0.5	1.5	-0.9	0.0	-0.0	-0.7	-0.5	-0.7	-1.2	0.5	-0.3	-0.4	1.1	-0.7	-0.7	-1.1	-1.2	-0.7	-0.3	-0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.9	0.8	-0.1	-0.2	0.4	0.6	0.9	0.5	-1.4	1.0	1.4	-0.4	0.1	1.0	0.8	1.3	0.3	0.7	0.1	1.0
Trunk fat mass	0.3	1.1	5.6	-1.0	0.8	0.9	-0.0	-0.5	0.3	0.5	2.4	-2.0	-1.1	1.0	0.5	-0.4	-1.1	-1.3	0.0	0.1	0.4	-1.8
Past tobacco smoking	0.3	0.6	3.2	-0.6	-0.4	-0.3	-0.4	-0.9	-0.6	1.0	0.3	-0.4	-1.1	0.9	-0.2	-0.5	-0.8	-0.9	-0.5	-0.4	-0.4	-1.8
Hair/balding pattern: Pattern 2	0.3	0.4	2.0	-0.4	0.2	0.1	-0.2	-0.4	0.1	0.4	1.2	-0.6	-1.2	1.4	0.4	-0.1	-0.4	-0.6	-0.3	-0.1	-0.2	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.6	5.8	0.2	0.2	0.3	0.3	0.8	0.0	0.3	1.3	-0.1	0.5	0.5	0.4	-0.6	-0.3	-0.6	0.4	-0.3	0.9	2.4
Falls in the last year	0.3	0.4	1.3	-0.7	0.1	0.1	-0.6	-0.2	-0.6	-0.9	-0.5	-1.1	-1.1	0.6	-0.2	-0.6	0.1	-1.0	-0.2	-0.6	-0.6	-0.8
Arm fat mass (right)	0.3	1.1	7.2	-0.7	1.1	1.0	0.1	-0.2	0.4	0.7	2.7	-1.6	-0.7	0.9	0.8	-0.1	-1.0	-1.0	0.1	0.4	0.5	-1.7
Medication: Paracetamol	0.3	0.5	2.7	-0.2	-0.6	-0.6	-0.6	0.0	-0.7	0.3	-0.1	-0.5	0.7	-1.6	-0.3	-0.2	0.1	-0.7	-0.3	-0.3	-0.9	-1.3
Gout (self-reported)	0.3	0.4	1.3	-0.5	-0.4	-0.5	-0.5	-0.6	-0.5	1.2	0.6	-0.6	0.6	-0.8	-0.5	-0.4	-0.4	-0.6	-0.4	-0.4	-0.5	-0.9
Medication: Ventolin 100micrograms inhaler	0.3	0.4	3.4	-0.1	0.4	0.6	0.3	-0.1	0.1	-0.8	0.6	0.1	-0.0	1.9	0.7	0.1	-0.6	-0.3	0.1	0.3	0.9	0.5
Comparative body size at age 10	0.3	0.8	2.4	0.5	1.6	1.3	0.9	1.0	0.5	-0.1	1.4	-0.1	0.2	0.6	0.5	0.5	0.5	0.2	1.0	0.8	1.0	1.5
Angina (self-reported)	0.3	0.4	2.0	-0.7	-0.9	-0.9	-0.6	0.2	-0.2	-0.4	-0.1	0.1	0.2	0.3	-0.3	-0.9	-1.4	0.2	-1.0	-0.8	0.0	1.0
Medication: Omeprazole	0.3	0.4	2.4	1.0	0.3	0.1	0.3	0.4	0.6	0.2	-0.4	1.6	-0.5	-0.4	-0.6	0.7	0.9	0.9	0.4	0.5	0.1	0.2
Medication: Seretide 50 evohaler	0.3	0.4	2.3	0.6	-0.2	0.0	0.1	0.0	-0.2	-0.3	1.1	0.2	-0.6	1.5	-0.2	-0.0	-0.7	0.8	-0.1	0.1	0.8	1.1
Whole body fat mass	0.3	1.2	5.8	-1.0	0.9	1.0	-0.1	-0.6	0.3	0.5	2.4	-2.0	-0.8	1.1	0.5	-0.4	-1.2	-1.3	-0.0	0.1	0.4	-1.9
Leg fat mass (right)	0.3	1.1	7.8	-0.6	1.0	1.0	0.2	-0.3	0.4	0.8	2.8	-1.5	-0.6	1.3	0.6	-0.2	-0.9	-0.9	0.2	0.3	0.6	-1.6
Supplements: Vitamin C	0.3	0.3	2.6	0.5	-0.3	0.0	0.4	0.3	0.7	0.4	0.2	1.3	0.1	0.4	-0.1	0.3	0.1	0.6	0.2	0.2	0.3	1.6
Knee pain experienced in last month	0.3	0.4	0.9	0.7	0.8	0.8	0.8	0.5	0.9	-0.5	0.7	-0.1	-0.0	-0.2	0.7	0.6	0.3	0.8	0.6	0.7	1.0	-0.1
Illnesses of father: Heart disease	0.3	0.4	2.0	0.5	0.1	0.1	-0.0	1.0	-0.3	-1.4	-1.2	-0.5	0.1	0.4	0.2	0.2	0.1	0.5	0.3	0.1	0.5	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.6	1.1	0.2	-0.4	0.4	0.7	0.4	-0.4	-1.2	1.1	0.7	-0.9	0.4	1.1	1.2	1.2	0.6	0.9	0.2	1.1
Arm fat mass (left)	0.3	1.2	5.8	-1.1	0.8	0.8	-0.2	-0.7	0.0	0.5	2.4	-1.9	-0.8	0.8	0.5	-0.5	-1.4	-1.4	-0.2	0.0	0.2	-2.0
Commuting to job workplace: Public transport	0.3	0.4	2.9	0.5	0.6	0.8	0.6	0.5	0.6	0.5	-0.5	0.2	0.1	1.7	0.2	0.1	0.4	-0.3	0.7	0.3	0.5	0.6
Leg fat percentage (left)	0.3	1.3	4.7	-1.5	0.1	0.2	-0.8	-1.1	-0.5	0.5	1.4	-2.2	-1.0	1.1	-0.0	-1.0	-1.9	-1.4	-0.8	-0.5	-0.2	-1.8
Risk taking	0.3	0.4	3.7	0.4	-0.7	-0.3	-0.5	-0.1	-0.8	-0.2	0.1	-0.3	-1.9	-0.3	-0.9	-0.5	-0.4	0.5	-0.3	-0.5	-0.2	0.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.9	0.4	-0.1	-0.3	-0.2	0.1	-0.2	0.6	-0.7	-0.1	-0.0	-1.7	-0.1	0.6	0.8	0.4	0.2	0.2	-0.6	-1.2
Heart disease (siblings)	0.3	0.3	1.1	-0.3	-1.0	-0.9	-0.3	-0.1	-0.5	1.1	0.1	0.9	0.1	0.2	-0.3	-0.8	-0.5	-0.0	-0.6	-0.8	-0.3	-0.1
Pack years of smoking	0.3	0.4	1.9	-0.7	-0.2	0.3	0.0	-0.9	-0.1	-0.6	1.4	-1.1	-0.4	0.4	-0.3	-0.3	-1.2	-0.6	-0.3	-0.0	0.4	-0.4
Leg fat mass (left)	0.3	1.1	7.8	-0.5	1.1	1.2	0.3	-0.1	0.5	0.8	2.8	-1.3	-0.4	1.5	0.7	-0.2	-0.9	-0.9	0.3	0.4	0.7	-1.4
Bipolar Disorder or Schizophrenia	0.2	0.6	3.6	0.5	-0.5	-0.8	0.1	0.5	0.1	-1.9	-1.0	0.6	0.9	-1.0	-1.5	-0.0	0.5	0.4	0.0	-0.2	-0.3	0.6
Schizophrenia (2018)	0.2	0.5	4.3	0.3	-0.5	-0.7	0.3	0.5	0.3	-2.1	0.1	0.7	-0.3	-0.4	-1.3	-0.3	-0.2	0.3	-0.1	-0.3	0.1	0.9
Schizophrenia vs Biploar Disorder	0.2	0.2	1.2	0.4	0.1	0.2	0.7	-0.1	0.6	-0.9	0.6	-0.1	-1.1	0.3	-0.2	0.1	0.3	0.1	0.6	0.2	0.4	-0.1
Alzheimer’s Disease (in mother)	0.2	0.3	2.1	-0.1	-0.6	-0.6	-0.3	-0.9	-0.3	0.0	-0.6	0.0	-1.5	0.1	-0.2	-0.1	-0.4	0.0	-0.6	-0.2	-0.3	0.0
Alzheimer’s Disease (including proxy)	0.2	0.2	1.6	0.1	-0.4	-0.6	-0.2	-0.7	-0.1	0.4	0.2	0.3	-1.3	-0.7	-0.5	0.1	0.1	0.1	-0.5	-0.3	-0.6	-0.0
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.3	0.6	0.5	0.8	0.8	0.8	1.0	0.2	0.3	1.0	0.5	1.1	0.5	0.6	1.1	0.4	0.8	0.5	0.5	1.1
Breast Cancer	0.2	0.5	1.4	-0.9	-0.4	-0.3	-0.8	-1.0	-1.1	0.3	-0.2	-0.6	-1.2	0.6	-0.0	-0.9	-0.8	-0.9	-0.5	-1.1	-0.3	-0.5
Ovarian Cancer	0.2	0.3	1.9	0.2	0.4	0.2	0.3	0.2	0.3	0.9	0.8	0.2	0.7	1.4	-0.2	-0.1	0.2	0.1	0.2	0.0	0.2	0.6
Coronary Artery Disease (CAD)	0.2	0.3	1.2	-0.7	0.1	0.0	-0.0	-0.5	0.3	-1.0	0.6	-0.8	0.1	-0.3	-0.3	-0.6	-1.1	-0.6	-0.7	-0.3	0.0	-0.1
Schizophrenia (2014)	0.2	0.5	2.9	-0.0	-1.0	-1.1	-0.1	0.2	-0.2	-1.7	-0.2	0.3	-0.3	-0.5	-1.3	-0.4	-0.5	-0.1	-0.4	-0.6	-0.2	0.7
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.7	-0.4	-0.3	-0.5	-0.7	0.0	-0.9	-0.5	-0.7	-0.5	0.3	0.3	-0.4	-0.3	0.1	-0.4	-0.3	-0.3	-0.6	-0.0
Blood Platelet Count	0.2	2.0	5.6	-0.4	-1.9	-1.4	-1.1	-2.3	-2.0	-1.3	-1.3	-1.6	-0.8	-2.0	-2.4	-0.6	-0.0	-0.3	-0.7	-0.8	-1.5	-1.3
BMI	0.2	1.4	8.3	-0.7	1.3	1.5	0.4	0.0	0.8	1.2	2.9	-1.0	1.0	2.1	1.1	-0.1	-1.3	-0.7	0.2	0.6	1.1	-0.9
Pack years adult smoking proportion	0.2	0.3	1.9	-0.4	-0.1	0.3	0.1	-0.7	-0.1	-0.5	1.4	-1.1	-0.0	0.3	-0.2	-0.1	-0.9	-0.5	-0.1	0.1	0.5	-0.4
Fed-up feelings	0.2	0.4	2.0	0.1	0.4	0.6	0.1	1.0	0.4	0.4	-0.1	1.0	1.4	0.7	0.2	0.0	0.0	0.0	0.3	0.2	0.5	1.0
Qualifications: CSEs or equivalent	0.2	0.2	1.4	-0.2	-0.1	-0.3	-0.1	0.0	-0.2	1.1	0.8	1.2	0.7	0.3	0.1	-0.2	0.1	-0.0	-0.1	-0.3	-0.0	0.4
Stomach or abdominal pain in last month	0.2	0.3	1.1	0.8	-0.5	-0.3	0.0	0.7	-0.2	1.1	0.4	0.3	0.6	-0.9	-0.3	0.3	-0.1	0.8	-0.2	-0.0	0.1	0.3
Body mass index (BMI)	0.2	1.0	6.5	-0.7	1.1	1.1	0.2	0.1	0.5	0.6	2.5	-1.2	0.0	1.4	0.8	-0.2	-1.1	-0.9	0.1	0.3	0.7	-1.3
Hearing difficulty/problems with background noise	0.2	0.3	0.9	0.1	0.7	0.6	0.3	0.4	0.4	0.8	0.9	0.4	0.3	0.7	0.9	0.2	-0.3	0.2	0.5	0.4	0.9	0.6
Had menopause	0.2	0.3	1.8	0.4	0.0	0.1	0.3	0.3	0.3	-0.5	-0.9	1.4	-0.1	0.5	0.3	0.6	-0.3	0.7	-0.0	0.5	0.6	0.2
Had other major operations	0.2	0.2	0.6	0.7	-0.2	-0.2	0.3	0.6	-0.3	-0.4	-0.7	0.8	-0.0	0.0	-0.5	-0.0	0.6	0.8	0.4	-0.1	0.4	0.5
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.3	0.8	0.1	0.2	0.6	0.6	0.2	-0.5	0.2	0.8	0.4	0.1	-0.8	0.3	0.4	0.6	0.3	0.1	0.3	1.5
Illnesses of siblings	0.2	0.3	1.5	0.3	0.4	0.3	-0.0	-0.3	0.2	-0.2	-0.2	-0.1	-0.2	-1.2	-0.0	0.7	1.1	-0.0	0.4	0.5	-0.5	-1.2
Hip circumference	0.2	1.0	8.8	-0.2	1.0	1.0	0.4	0.6	0.6	0.8	3.0	-1.3	-0.8	1.1	0.7	-0.0	-0.7	-0.7	0.5	0.5	0.8	-0.9
Time employed in main current job	0.2	0.2	1.2	-0.1	0.3	-0.2	0.0	0.3	-0.3	-0.2	1.1	0.4	-0.2	1.0	-0.3	-0.8	-0.7	-0.2	-0.2	-0.4	0.3	0.3
Length of working week for main job	0.2	0.3	0.8	0.2	-0.4	-0.3	-0.1	-0.1	-0.3	-0.9	-0.8	-0.5	-0.3	-0.8	-0.9	-0.4	0.7	-0.3	0.0	-0.4	-0.6	-0.3
Exposure to tobacco smoke at home	0.2	0.2	0.8	0.4	0.5	0.4	0.3	0.3	0.3	-0.2	-0.4	0.6	0.3	-0.4	0.2	0.6	0.8	0.1	0.4	0.5	0.3	0.9
Hair/balding pattern: Pattern 4	0.2	0.4	2.9	0.2	0.3	0.3	0.4	1.0	0.4	-0.7	-0.8	0.8	0.1	-0.5	0.4	0.1	-0.0	0.6	0.1	0.2	0.7	1.7
Pulse wave reflection index	0.2	0.3	1.1	0.2	-0.5	-0.5	-0.2	1.1	-0.2	-0.2	-0.7	0.8	0.5	0.1	-0.0	-0.0	-0.0	0.9	-0.2	-0.3	0.1	1.0
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.2	0.4	-0.8	-0.8	-0.2	0.0	-0.2	-0.0	-0.9	0.9	-1.1	-0.5	-1.0	0.1	0.8	0.2	-0.2	-0.2	-0.6	0.0
Headache pain in last month	0.2	0.4	2.6	-0.4	-0.5	-0.2	0.0	-0.3	-0.1	1.1	0.7	-0.5	-0.4	1.6	0.0	-0.4	-1.2	-0.1	-0.5	-0.3	0.5	0.8
Medication: Amlodipine	0.2	0.3	1.5	-0.1	-0.6	-1.0	-0.6	0.3	-0.7	-0.0	-1.2	-0.2	-0.4	0.4	-0.5	-0.5	-0.2	0.3	-0.5	-0.6	-0.4	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.0	0.1	0.3	0.4	0.2	0.3	0.4	-0.7	0.9	-0.4	-0.2	1.0	-0.3	-0.2	-0.4	-0.0	0.1	-0.0	0.7	1.0
Eye problems/disorders: None of the above	0.2	0.2	1.4	0.3	-0.2	-0.5	-0.1	0.1	-0.3	0.0	-0.6	-0.5	-0.5	-1.2	-0.2	0.0	0.5	0.1	0.0	0.0	-0.3	0.8
Emphysema/chronic bronchitis	0.2	0.2	0.9	-0.7	-0.1	0.1	-0.4	-0.2	-0.5	-0.9	0.2	-0.8	-0.2	0.1	-0.3	-0.5	-0.5	-0.4	-0.3	-0.5	0.3	0.7
Alcohol intake frequency.	0.2	0.6	3.3	-0.7	0.5	0.6	-0.1	-0.3	-0.1	0.3	1.7	-1.8	0.4	0.5	0.2	-0.3	-0.7	-1.0	0.1	0.0	0.3	-1.1
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.8	0.4	-0.1	-0.3	0.2	0.1	0.1	-0.1	-0.3	0.6	-0.1	-1.3	-0.2	0.6	0.5	0.6	-0.0	0.3	-0.2	-0.7
Ever had bowel cancer screening	0.2	0.2	1.1	0.7	-0.3	-0.3	0.1	0.2	-0.1	0.5	-1.1	0.7	-0.2	-0.1	-0.5	0.2	0.2	0.7	-0.0	0.0	-0.0	0.9
Qualifications: nursing, teaching	0.2	0.3	1.6	0.7	-0.5	-0.4	0.1	-0.2	0.2	0.2	0.1	1.0	-0.0	-1.3	-0.4	0.7	1.0	0.5	0.0	0.3	-0.8	-0.2
Commuting to job workplace: Walk	0.2	0.2	1.7	0.2	-0.4	-0.5	-0.2	0.3	-0.2	-0.0	-1.3	-0.1	-0.4	-0.1	0.0	0.1	0.0	0.6	-0.3	-0.1	-0.0	1.2
Medication for cholesterol	0.2	0.4	2.1	0.4	0.3	0.2	0.1	-0.3	0.2	-0.2	0.0	-0.2	-0.8	-1.4	0.6	0.5	1.3	-0.5	0.7	0.5	-0.5	-0.6
Hearing aid user	0.2	0.2	2.3	0.3	-0.4	-0.6	-0.1	0.2	-0.2	0.5	-1.5	0.2	0.0	-0.2	-0.5	-0.0	0.3	0.2	-0.2	-0.1	-0.5	0.5
Medication: Paracetamol	0.2	0.3	1.8	-0.3	-0.6	-0.4	-0.4	-0.1	-0.5	0.1	-0.3	-0.6	0.1	-0.8	-0.1	-0.1	-0.3	-0.8	-0.2	-0.2	-0.6	-1.3
Myopia	0.2	0.3	2.5	-0.5	-0.2	-0.1	0.1	-0.5	0.5	-0.1	-0.1	0.6	0.3	1.6	0.0	-0.4	-0.7	0.0	-0.3	-0.4	0.5	0.8
Blood Red Count	0.1	0.6	2.5	0.2	0.9	0.9	0.6	-0.1	0.6	0.3	1.1	-0.6	0.6	0.2	0.9	0.5	0.9	-0.4	1.0	0.7	0.3	-1.6
Blood White Count	0.1	0.4	3.0	-0.3	0.1	0.2	0.0	-0.8	-0.1	0.1	0.6	-1.5	1.7	0.1	0.0	0.1	0.6	-0.6	0.3	0.1	-0.3	-0.7
Heel T-Score	0.1	0.6	3.2	-0.2	-0.9	-1.1	-0.5	-0.2	0.3	0.2	-1.3	-0.2	-1.8	-1.4	-0.4	0.2	-0.5	0.4	-0.9	-0.2	-0.8	0.4
Hair Pigment	0.1	3.1	6.7	-1.1	-2.1	-1.7	-1.9	-1.0	-2.0	-2.5	-0.9	-1.1	-2.3	-1.0	-2.6	-1.8	-2.5	-0.2	-2.3	-1.9	-1.1	-0.4
Tanning	0.1	1.5	3.4	1.2	0.8	0.7	1.1	1.8	1.3	0.7	0.8	1.7	0.9	1.7	1.3	0.9	0.6	1.7	0.8	1.0	1.3	1.7
Impedance of leg (right)	0.1	0.6	2.8	-0.2	-0.7	-0.6	-0.8	-1.2	-0.9	-0.1	-1.7	-0.8	-0.8	-0.9	-0.6	-0.0	0.6	-0.1	-0.3	-0.3	-1.0	-0.8
Average weekly fortified wine intake	0.1	0.1	1.1	0.1	0.0	-0.0	-0.1	-0.2	0.0	0.1	0.1	0.0	0.0	-0.8	-0.3	0.4	-0.0	1.1	-0.3	0.1	0.0	0.1
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.5	-0.3	-0.4	-0.1	-0.1	-0.4	-0.1	-0.5	0.5	0.2	-0.2	0.2	-0.7	-0.3	-0.6	-0.2	-0.3	-0.4	-0.0	0.3
Medication: Atenolol	0.1	0.2	0.6	-0.6	-0.2	-0.3	-0.1	0.2	-0.1	0.7	0.8	0.1	0.1	-0.1	0.3	-0.6	-0.6	-0.5	-0.3	-0.4	0.0	-0.3
Impedance of leg (left)	0.1	0.5	3.5	-0.3	-0.8	-0.5	-0.7	-1.0	-0.8	-0.2	-1.9	-0.6	-0.5	-0.5	-0.8	-0.3	0.3	-0.1	-0.2	-0.5	-0.8	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.4	0.3	-0.4	-0.5	0.2	-0.0	0.6	0.1	-1.2	0.4	1.0	-1.1	0.0	0.6	0.6	0.6	-0.1	0.3	-0.4	0.6
Mouth/teeth dental problems: Dentures	0.1	0.2	0.7	0.7	0.3	0.1	0.2	0.5	0.2	0.7	0.1	-0.2	-0.1	-0.5	0.6	0.4	-0.1	0.9	0.1	0.4	0.5	0.2
Number of full brothers	0.1	0.2	1.4	-0.3	0.0	-0.2	-0.1	0.5	0.0	-0.9	-0.3	-0.0	1.2	-0.0	-0.1	0.0	-0.0	-0.3	-0.2	0.1	-0.1	0.5
Migraine (self-reported)	0.1	0.2	1.1	-0.2	-0.5	-0.5	-0.4	-0.2	-0.3	-0.3	-0.0	-1.0	0.2	-0.5	-0.7	0.1	-0.0	0.0	-0.4	-0.2	-0.5	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.5	-0.0	0.7	0.6	0.2	-0.4	0.2	-0.1	0.5	-0.0	0.5	0.3	0.5	0.5	0.5	-0.4	0.6	0.6	0.2	-0.4
Mineral and other dietary supplements	0.1	0.1	0.7	0.1	0.6	0.3	0.2	-0.2	0.2	0.2	0.2	0.1	-0.3	0.1	0.3	0.2	0.5	-0.8	0.1	0.3	-0.3	-0.8
Financial situation satisfaction	0.1	0.2	0.8	-0.1	0.6	0.7	0.0	0.2	-0.0	-0.1	0.4	-0.1	0.9	0.9	0.4	0.1	-0.3	-0.2	0.1	0.2	0.3	-0.2
Irritability	0.1	0.1	1.1	0.2	-0.2	-0.1	0.1	0.3	0.2	-0.5	0.2	0.6	0.1	0.4	-0.0	-0.2	-0.2	0.1	-0.0	-0.1	0.5	1.1
Basal cell carcinoma (self-reported)	0.1	0.1	0.6	-0.0	-0.2	0.0	-0.3	-0.4	-0.3	0.2	0.3	-0.6	-0.7	0.6	-0.3	-0.2	-0.3	0.1	-0.0	-0.2	0.1	0.2
Alcohol drinker status: Previous	0.1	0.1	1.0	0.3	0.0	-0.2	-0.1	-0.2	-0.1	0.6	1.0	-0.5	0.3	-0.0	-0.3	0.0	0.3	-0.1	0.2	0.1	0.1	0.5
Pulse rate, automated reading	0.0	0.1	1.1	-0.1	0.1	0.1	0.0	-0.2	0.3	-1.1	-0.2	-0.5	-0.4	-0.1	-0.4	-0.0	0.3	-0.4	0.2	-0.1	-0.3	-0.5

Hub : Genes

TPRA1

Models

Trait associations