TWAS hub - TRDMT1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.3730	0.0570	2.1e-13	0.214	NA	0.240	NA	0.186	2.4e-17	NA	1.5e-19	NA	3.9e-15
2	GTEx	Adipose Visceral Omentum	0.2760	0.0600	1.2e-06	0.223	NA	0.139	NA	0.175	8.1e-12	NA	1.1e-07	NA	2.0e-09
3	GTEx	Artery Aorta	0.2280	0.0640	1.8e-04	0.078	NA	0.076	NA	0.057	4.3e-05	NA	5.5e-05	NA	4.3e-04
4	GTEx	Artery Coronary	0.3080	0.1050	2.5e-03	0.128	NA	0.066	NA	0.021	4.3e-05	NA	3.0e-03	NA	6.2e-02
5	GTEx	Artery Tibial	0.2580	0.0443	1.4e-11	0.264	NA	0.262	NA	0.265	9.5e-21	NA	1.5e-20	NA	7.6e-21
6	GTEx	Brain Cerebellar Hemisphere	0.3130	0.1000	4.9e-03	0.204	NA	0.087	NA	0.162	5.9e-06	NA	3.1e-03	NA	5.9e-05
7	GTEx	Breast Mammary Tissue	0.2020	0.0610	8.0e-04	0.139	NA	0.110	NA	0.131	1.3e-07	NA	2.8e-06	NA	3.2e-07
8	GTEx	Breast Mammary Tissue (Male)	0.3168	0.1955	1.4e-01	0.003	NA	-0.005	NA	-0.011	2.8e-01	NA	4.5e-01	NA	6.9e-01
9	GTEx	Heart Atrial Appendage	0.2550	0.0830	2.2e-03	0.108	NA	0.085	NA	0.118	1.4e-05	NA	1.2e-04	NA	6.0e-06
10	GTEx	Nerve Tibial	0.2698	0.0657	4.1e-06	0.105	NA	0.072	NA	0.119	7.0e-08	NA	8.6e-06	NA	8.9e-09
11	GTEx	Pancreas	0.2470	0.0750	1.4e-03	0.173	NA	0.096	NA	0.172	8.7e-08	NA	7.2e-05	NA	9.6e-08
12	GTEx	Skin Not Sun Exposed Suprapubic	0.2170	0.0600	6.4e-05	0.111	NA	0.083	NA	0.099	1.1e-06	NA	2.7e-05	NA	4.6e-06
13	GTEx	Skin Sun Exposed Lower leg	0.0990	0.0350	2.9e-03	0.016	NA	0.039	NA	0.040	1.7e-02	NA	3.4e-04	NA	3.0e-04
14	GTEx	Testis	0.1850	0.0720	8.8e-03	0.079	NA	0.065	NA	0.105	2.3e-04	NA	7.6e-04	NA	2.2e-05
15	GTEx	Thyroid	0.2060	0.0430	6.1e-08	0.223	NA	0.218	NA	0.223	5.6e-17	NA	1.3e-16	NA	4.8e-17
16	NTR	Blood	0.0448	0.0134	4.2e-05	0.018	0.019	0.031	0.025	0.020	8.9e-07	8.1e-07	2.7e-10	1.3e-08	2.7e-07
17	TCGA	Breast Invasive Carcinoma	0.0230	0.0111	5.5e-04	0.009	0.013	0.009	NA	0.011	5.3e-03	7.4e-04	4.1e-03	NA	1.9e-03
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0808	0.0255	3.7e-11	0.125	0.105	0.112	NA	0.121	5.8e-14	7.7e-12	1.3e-12	NA	1.8e-13
19	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0670	0.0340	1.4e-03	0.035	0.047	0.019	NA	0.029	4.1e-03	1.1e-03	2.9e-02	NA	8.4e-03
20	TCGA	Brain Lower Grade Glioma	0.0834	0.0282	1.8e-11	0.105	0.105	0.101	NA	0.101	5.4e-12	5.4e-12	1.6e-11	NA	1.5e-11
21	TCGA	Pancreatic Adenocarcinoma	0.2380	0.0840	1.6e-04	0.013	0.064	0.050	NA	0.034	8.6e-02	1.2e-03	3.8e-03	NA	1.5e-02
22	TCGA	Pheochromocytoma and Paraganglioma	0.1010	0.0480	3.2e-03	0.012	0.026	0.004	NA	0.013	1.1e-01	3.2e-02	2.1e-01	NA	9.1e-02
23	TCGA	Prostate Adenocarcinoma	0.0673	0.0314	2.9e-05	0.053	0.038	0.055	NA	0.050	3.1e-06	6.9e-05	2.0e-06	NA	5.5e-06
24	TCGA	Testicular Germ Cell Tumors	0.1620	0.0800	8.7e-04	0.079	0.033	-0.008	NA	0.020	9.5e-04	2.5e-02	8.4e-01	NA	6.2e-02
25	TCGA	Thyroid Carcinoma	0.1920	0.0540	0.0e+00	0.170	0.189	0.201	NA	0.218	2.4e-16	4.3e-18	2.9e-19	NA	6.6e-21

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Hair/balding pattern: Pattern 3	6.9	10.3	17.9	-3.3	-3.4	-3.3	-3.7	-3.5	-3.5	-3.4	-2.7	-3.6	-3.4	-3.7	-3.4	-2.4	-3.6	1.6	-4.2	-3.6	-2.7	-3.1	-2.8	-3.8	-3.7	0.2	-3.6
Medication: Paracetamol	6.9	11.5	17.0	4.1	3.4	3.8	3.9	3.5	3.3	3.9	3.0	3.6	3.3	3.5	3.7	1.2	3.8	0.5	3.9	3.8	4.0	3.6	3.5	3.7	4.0	1.2	3.9
Medication: Paracetamol	6.5	10.0	16.2	4.0	3.2	3.4	3.6	3.4	3.1	3.7	3.0	3.4	3.2	3.4	3.6	0.9	3.5	0.2	3.7	3.5	3.5	3.2	3.2	3.5	3.7	1.0	3.6
HbA1C	5.2	5.7	10.0	2.8	2.9	2.3	2.5	2.9	2.5	3.2	2.6	2.9	2.8	2.7	2.1	-0.2	2.5	-0.4	2.5	2.5	3.0	1.7	2.8	2.4	2.5	0.7	2.4
Smoking status: Previous	4.6	6.9	15.5	-3.9	-3.2	-2.3	-2.7	-3.1	-3.0	-3.4	-3.4	-3.0	-3.1	-3.1	-2.5	-1.9	-2.6	0.5	-2.9	-2.6	-3.0	-0.9	-0.8	-2.1	-2.8	0.5	-2.6
Headache pain in last month	4.3	7.3	12.7	3.2	2.6	3.2	3.3	2.7	2.5	3.0	1.8	2.9	2.4	2.9	3.4	1.4	3.2	-0.0	2.4	3.2	3.6	2.8	2.4	2.3	3.2	2.4	3.2
Blood Platelet Count	3.8	43.5	80.1	7.5	6.1	7.2	7.6	6.5	6.1	6.9	4.8	6.8	6.1	6.7	7.7	5.4	7.6	1.1	6.8	7.6	8.9	7.7	5.2	7.6	7.7	3.2	7.7
Worry too long after embarrassment	3.8	6.3	10.1	3.1	3.0	2.1	2.7	3.0	2.8	2.9	3.2	2.9	2.9	3.1	2.3	1.4	2.6	-1.0	3.1	2.6	2.7	1.5	1.8	2.7	2.7	-0.6	2.7
Pack years adult smoking proportion	3.6	5.5	10.6	3.0	1.8	3.3	2.8	2.1	1.8	2.3	1.4	2.1	1.9	2.1	3.0	1.2	2.8	1.5	2.4	2.8	2.6	2.9	2.5	2.5	2.9	1.6	2.9
Time employed in main current job	3.5	4.1	8.6	1.9	1.9	1.9	2.2	2.1	2.0	2.3	1.2	2.1	1.8	2.1	2.3	2.9	2.2	0.2	2.0	2.2	2.5	2.2	2.0	2.3	2.2	0.8	2.2
Medication: Co-codamol	3.1	3.6	6.2	2.5	2.3	2.0	2.1	2.4	2.5	2.4	2.0	2.3	2.3	2.3	1.9	0.6	2.0	-0.4	2.2	2.0	2.1	0.7	0.8	1.7	2.0	-0.2	1.9
Wears glasses or contact lenses	3.0	3.4	7.1	-1.8	-2.1	-2.0	-2.0	-2.0	-2.1	-2.0	-1.8	-2.2	-2.1	-2.1	-1.8	-1.2	-2.0	1.8	-1.9	-2.0	-1.2	-1.5	-2.7	-1.5	-2.0	-0.0	-2.0
Tinnitus: Yes, but not now, but have in the past	2.9	3.0	6.2	2.0	1.6	2.1	2.1	1.7	1.6	1.8	0.9	1.9	1.5	1.8	2.2	0.7	2.1	-0.8	2.1	2.1	1.5	2.0	1.7	2.5	2.1	0.1	2.0
Pack years of smoking	2.9	4.2	8.3	2.7	1.5	2.9	2.4	1.8	1.5	2.0	1.1	1.8	1.6	1.8	2.7	1.1	2.4	1.6	2.1	2.4	2.2	2.5	2.0	2.2	2.6	1.4	2.6
Hearing aid user	2.7	3.0	5.2	2.2	1.8	2.3	1.9	1.8	1.7	1.8	1.6	1.8	1.7	1.8	2.1	0.6	2.0	0.4	2.2	2.0	1.9	1.9	1.0	2.0	1.9	0.2	2.0
Medication for pain relief, constipation, heartburn	2.6	4.4	8.2	-2.9	-1.9	-2.3	-2.4	-2.0	-2.0	-2.4	-1.3	-2.1	-1.8	-2.2	-2.5	0.2	-2.4	-0.3	-2.4	-2.4	-2.0	-2.4	-2.7	-2.6	-2.4	-0.1	-2.3
Bipolar Disorder (2011)	2.5	2.4	4.4	-1.7	-1.5	-1.6	-1.7	-1.6	-1.4	-1.6	-1.3	-1.6	-1.5	-1.6	-1.5	-1.9	-1.7	0.2	-1.7	-1.7	-1.8	-1.7	-1.5	-2.1	-1.8	0.2	-1.7
Past tobacco smoking	2.4	4.4	9.6	3.1	2.5	1.9	2.2	2.4	2.3	2.7	2.5	2.4	2.4	2.4	2.2	1.7	2.1	-0.3	2.3	2.1	2.9	0.8	0.5	1.8	2.2	0.3	2.1
Breastfed as a baby	2.4	2.9	6.2	-2.3	-2.3	-1.4	-1.7	-2.2	-2.5	-2.3	-1.9	-2.2	-2.2	-2.2	-1.4	-1.0	-1.6	0.6	-1.9	-1.6	-1.0	-0.1	-1.4	-1.6	-1.5	1.4	-1.5
Medication for cholesterol	2.4	3.7	8.4	2.2	2.6	1.5	1.6	2.4	2.4	2.5	2.9	2.3	2.5	2.1	1.0	1.3	1.5	-1.0	2.5	1.5	2.4	0.4	-0.4	2.4	1.7	-1.8	1.5
Hayfever/allergic rhinitis (self-reported)	2.3	3.0	5.3	-1.8	-1.6	-1.9	-1.9	-1.7	-1.6	-1.8	-1.2	-1.8	-1.6	-1.7	-1.9	-2.1	-2.0	-0.9	-1.6	-2.0	-2.3	-2.1	-1.7	-1.9	-2.0	-0.6	-2.0
Medication: Blood pressure	2.3	4.4	10.4	-2.5	-2.4	-2.1	-2.0	-2.3	-2.2	-2.6	-2.4	-2.3	-2.4	-2.1	-1.7	-1.7	-1.9	-0.7	-2.8	-1.9	-3.2	-1.9	0.0	-2.9	-2.1	0.7	-1.9
Diastolic blood pressure, automated reading	2.3	7.2	13.9	-2.7	-3.4	-1.3	-2.1	-3.1	-3.4	-3.3	-3.7	-3.0	-3.6	-3.4	-1.3	-2.9	-2.1	2.7	-3.6	-2.1	-2.1	-1.0	-1.6	-3.4	-2.2	3.0	-2.0
Schizophrenia (2014)	2.0	4.3	11.9	-2.1	-2.3	-2.1	-2.0	-2.3	-2.2	-2.4	-2.6	-2.1	-2.3	-2.3	-1.6	-3.4	-2.1	1.0	-2.4	-2.1	-1.5	-1.8	-1.6	-2.0	-2.2	0.8	-2.1
Hayfever, allergic rhinitis or eczema	2.0	4.3	7.5	-2.0	-2.7	-1.6	-2.0	-2.6	-2.6	-2.6	-2.6	-2.5	-2.7	-2.5	-1.4	-1.7	-1.9	0.8	-2.3	-2.0	-2.3	-1.1	-2.0	-2.2	-2.0	0.9	-1.9
Bipolar Disorder or Schizophrenia	1.9	4.6	15.5	-2.3	-2.2	-2.0	-2.2	-2.3	-2.1	-2.5	-2.2	-2.2	-2.2	-2.3	-1.9	-3.9	-2.3	0.5	-2.3	-2.3	-2.1	-2.1	-1.4	-2.2	-2.3	0.4	-2.3
Qualifications: CSEs or equivalent	1.9	2.6	5.2	-1.5	-1.5	-2.1	-1.7	-1.5	-1.6	-1.8	-1.0	-1.7	-1.8	-1.6	-1.7	0.1	-1.8	0.2	-1.8	-1.8	-2.2	-1.6	-1.7	-2.3	-1.7	-0.3	-1.6
Knee pain experienced in last month	1.9	3.0	6.8	1.8	0.8	2.1	2.1	1.1	0.9	1.2	-0.4	1.4	0.8	1.3	2.6	0.5	2.2	0.8	1.5	2.2	2.2	2.4	2.3	2.4	2.0	2.3	2.1
Medication: Gliclazide	1.9	2.2	5.6	-2.4	-1.8	-1.5	-1.7	-1.8	-1.8	-1.9	-1.4	-1.8	-1.6	-1.7	-1.5	-0.9	-1.7	0.5	-1.8	-1.7	-1.0	-0.3	-0.0	-1.2	-1.7	0.4	-1.5
Systolic Blood Pressure	1.8	9.1	21.2	-3.1	-3.7	-2.1	-2.7	-3.5	-3.9	-3.9	-3.6	-3.5	-3.7	-3.6	-1.8	-2.5	-2.6	2.0	-4.1	-2.6	-3.2	-1.1	-1.3	-4.6	-2.6	2.7	-2.4
High blood pressure	1.8	4.9	11.4	-2.2	-2.9	-1.4	-1.7	-2.6	-2.7	-2.9	-3.4	-2.6	-3.0	-2.4	-0.7	-1.5	-1.6	0.5	-3.2	-1.6	-3.0	-0.9	-0.4	-3.4	-1.7	2.1	-1.5
Qualifications: NVQ or HND or HNC or equivalent	1.8	2.2	5.4	-1.5	-1.7	-1.5	-1.6	-1.6	-1.8	-1.7	-1.4	-1.8	-1.6	-1.7	-1.3	-1.1	-1.5	2.3	-1.7	-1.5	-1.3	-1.2	-0.3	-1.3	-1.5	0.5	-1.5
LDL Cholesterol	1.7	2.7	10.1	1.6	0.8	1.7	1.9	1.2	0.9	1.2	0.1	1.3	1.1	1.2	1.9	1.2	2.0	1.9	1.2	2.0	3.2	2.3	0.3	1.6	1.9	2.6	1.9
Chronic bronchitis/emphysema (mother)	1.7	1.9	4.8	-1.6	-1.9	-0.8	-1.1	-1.7	-1.7	-1.8	-2.0	-1.7	-1.8	-1.7	-0.6	-1.9	-1.0	2.2	-1.3	-1.1	-0.8	0.4	-0.4	-1.1	-1.1	1.2	-1.0
Miserableness	1.7	2.9	5.0	2.2	1.8	1.7	2.0	1.9	1.9	1.7	1.6	1.9	1.8	1.9	1.8	1.1	1.9	-0.3	2.0	1.9	0.9	1.6	1.9	1.7	1.9	-0.7	1.9
Heart disease (siblings)	1.7	2.1	5.2	1.6	2.2	0.7	1.1	1.9	2.1	1.8	2.3	1.8	2.1	2.0	0.5	0.4	1.0	-2.1	1.5	1.0	0.3	-1.1	0.6	0.4	1.1	-1.8	1.0
Number of treatments/medications taken	1.6	2.9	10.6	2.4	1.1	1.8	2.0	1.3	1.1	1.5	0.5	1.5	1.1	1.6	2.6	0.1	2.0	0.2	1.5	2.0	0.9	2.5	3.3	1.4	2.0	1.4	2.1
Fed-up feelings	1.6	2.8	4.7	2.1	1.6	2.2	2.0	1.6	1.7	1.6	1.3	1.7	1.5	1.7	1.8	1.9	1.9	-0.8	2.0	1.9	1.0	1.5	1.9	2.0	1.9	-0.1	2.0
Medication: Seretide 50 evohaler	1.6	1.8	5.6	2.4	1.5	1.6	1.4	1.4	1.3	1.6	1.2	1.4	1.4	1.4	1.4	-0.2	1.3	0.1	1.7	1.3	1.4	1.5	1.3	1.4	1.5	0.2	1.4
Age started oral contraceptive pill	1.6	2.0	3.4	-1.7	-1.1	-1.8	-1.6	-1.3	-1.1	-1.4	-0.9	-1.4	-1.2	-1.3	-1.9	-1.1	-1.7	-0.9	-1.3	-1.7	-1.7	-1.8	-1.5	-1.6	-1.6	-0.7	-1.6
Alzheimer’s Disease (in mother)	1.5	1.7	3.3	1.8	1.4	1.3	1.4	1.4	1.3	1.6	1.2	1.5	1.5	1.4	1.6	0.7	1.4	0.0	1.3	1.4	1.4	1.0	1.8	1.3	1.5	0.4	1.4
Ovarian Cancer	1.5	2.0	3.3	1.7	1.7	1.5	1.4	1.7	1.6	1.6	1.8	1.6	1.7	1.6	1.3	-0.3	1.4	-0.1	1.6	1.4	1.4	1.1	1.6	1.7	1.4	-0.7	1.4
Cardiovascular Disease	1.5	4.9	12.7	-2.4	-3.0	-1.2	-1.6	-2.6	-3.0	-2.9	-3.0	-2.7	-3.1	-2.5	-0.7	-1.8	-1.4	1.1	-2.7	-1.5	-2.1	0.1	0.1	-3.0	-1.4	3.6	-1.2
Townsend deprivation index at recruitment	1.5	2.1	4.0	1.5	1.9	1.0	1.6	1.7	2.0	1.9	1.8	1.8	1.9	1.8	1.2	-1.1	1.4	-1.2	1.6	1.4	0.4	0.5	1.4	0.9	1.5	-0.9	1.4
Hip circumference	1.5	6.4	15.0	2.6	1.7	3.1	2.9	2.1	1.7	2.4	1.0	2.2	1.7	2.2	3.4	2.1	3.0	1.7	2.2	2.9	3.9	3.3	1.7	3.2	3.0	2.3	3.1
Hair/balding pattern: Pattern 4	1.5	3.6	11.4	-2.0	-0.8	-2.4	-2.2	-1.3	-0.8	-1.3	-0.5	-1.3	-0.7	-1.3	-2.9	-0.7	-2.3	-2.0	-1.0	-2.3	-3.4	-2.6	-0.9	-1.7	-2.3	-3.1	-2.4
Emphysema/chronic bronchitis	1.5	1.7	3.5	1.9	1.5	1.4	1.3	1.4	1.6	1.6	1.2	1.5	1.4	1.5	1.4	0.9	1.3	-0.3	1.7	1.3	1.3	0.9	0.5	1.5	1.3	-0.5	1.2
Chest pain or discomfort	1.5	2.2	5.0	1.5	0.8	1.8	1.8	1.0	1.0	1.1	0.0	1.2	0.8	1.1	2.2	1.3	1.8	0.4	1.3	1.8	1.7	2.2	2.2	1.9	1.7	1.8	1.8
Ever had bowel cancer screening	1.5	1.8	3.6	-1.9	-1.4	-1.5	-1.6	-1.5	-1.4	-1.6	-1.3	-1.5	-1.3	-1.5	-1.2	0.4	-1.6	-0.7	-1.0	-1.6	-1.9	-0.9	-0.4	-0.8	-1.6	-1.1	-1.6
Medication: Atorvastatin	1.5	1.9	3.8	-1.4	-1.9	-1.2	-1.1	-1.8	-1.9	-1.8	-1.8	-1.7	-1.9	-1.6	-0.6	-0.2	-1.1	1.8	-1.5	-1.1	-0.6	-0.2	-1.2	-1.2	-1.1	1.5	-0.9
Ever had prostate specific antigen (PSA) test	1.5	1.7	3.1	-1.2	-1.7	-1.2	-1.4	-1.5	-1.8	-1.7	-1.7	-1.6	-1.7	-1.5	-0.8	0.1	-1.3	-0.1	-1.4	-1.3	-1.7	-0.9	-1.4	-1.1	-1.3	0.3	-1.3
Vascular/heart problems diagnosed by doctor	1.5	4.1	9.8	2.0	2.7	1.2	1.6	2.4	2.5	2.6	3.1	2.4	2.7	2.2	0.6	1.3	1.5	-0.6	2.8	1.5	2.7	0.9	0.4	3.0	1.6	-1.9	1.4
Bipolar Disorder (2018)	1.4	2.2	6.5	-1.8	-1.4	-1.2	-1.6	-1.5	-1.4	-1.7	-1.1	-1.5	-1.4	-1.6	-1.5	-2.5	-1.7	-0.9	-1.4	-1.7	-1.9	-1.4	-0.4	-1.4	-1.6	0.1	-1.5
Depression (Nagel 2018)	1.4	2.0	4.5	1.9	1.4	1.7	1.6	1.6	1.4	1.4	1.2	1.5	1.3	1.4	1.5	1.0	1.6	0.2	1.4	1.6	1.5	1.5	2.1	0.9	1.6	0.9	1.6
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	7.0	2.3	1.3	1.8	1.7	1.4	1.4	1.5	0.7	1.5	1.4	1.3	1.8	0.4	1.7	0.2	1.4	1.7	1.5	1.4	2.6	1.5	1.8	0.9	1.6
Number of live births	1.4	1.9	3.7	-1.3	-1.2	-1.9	-1.7	-1.4	-1.3	-1.1	-0.9	-1.3	-1.3	-1.4	-1.8	-1.3	-1.7	1.1	-1.8	-1.7	-1.1	-1.4	-0.9	-1.7	-1.6	-0.1	-1.7
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	4.5	1.5	1.0	1.7	1.6	1.1	1.1	1.4	0.3	1.3	0.9	1.2	1.5	0.3	1.6	0.7	1.7	1.6	1.4	2.1	1.5	2.0	1.5	0.5	1.5
Medication: Bendroflumethiazide	1.4	2.1	5.1	-1.2	-1.4	-1.7	-1.5	-1.4	-1.5	-1.7	-0.9	-1.5	-1.5	-1.3	-1.2	-1.9	-1.5	-0.9	-1.6	-1.5	-2.2	-1.2	-1.5	-2.2	-1.4	-0.6	-1.3
Schizophrenia (2018)	1.3	2.6	8.6	-1.4	-1.8	-1.7	-1.5	-1.7	-1.6	-1.8	-1.9	-1.6	-1.7	-1.7	-1.2	-2.9	-1.5	1.4	-1.8	-1.6	-1.2	-1.5	-1.5	-1.7	-1.7	0.5	-1.7
Alzheimer’s Disease (in father)	1.3	1.4	2.5	-1.6	-1.4	-1.3	-1.4	-1.4	-1.5	-1.3	-0.8	-1.5	-1.3	-1.4	-0.9	-0.3	-1.3	-0.2	-1.4	-1.3	-0.6	-0.8	-1.3	-1.1	-1.4	0.5	-1.3
Crohns Disease (2017)	1.3	2.9	4.9	-1.9	-1.8	-1.6	-2.1	-1.8	-1.6	-2.1	-1.4	-2.0	-2.0	-2.1	-1.7	-0.5	-2.1	-0.1	-2.0	-2.1	-2.1	-1.2	-0.8	-2.2	-2.0	0.3	-2.1
Diabetes (father)	1.3	1.6	2.8	1.3	1.6	1.2	1.4	1.6	1.4	1.7	1.6	1.5	1.6	1.6	0.8	0.0	1.3	-0.9	1.5	1.3	1.0	0.4	-0.5	1.2	1.3	-1.1	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	6.0	1.7	1.3	1.5	1.5	1.4	1.4	1.3	0.9	1.4	1.3	1.4	1.4	0.5	1.5	0.0	1.3	1.5	0.9	1.5	2.5	0.9	1.5	0.4	1.5
Taking other prescription medications	1.3	2.0	9.1	1.8	1.4	1.2	1.5	1.4	1.4	1.5	1.2	1.5	1.4	1.5	1.7	0.2	1.5	-1.1	1.5	1.5	0.2	1.2	3.0	1.3	1.5	0.1	1.5
Forced vital capacity (FVC)	1.3	5.0	7.8	-2.7	-2.6	-2.1	-2.5	-2.7	-2.6	-2.8	-2.0	-2.6	-2.5	-2.6	-2.2	-2.0	-2.4	1.4	-2.4	-2.4	-2.3	-1.9	-1.3	-2.1	-2.5	0.5	-2.4
Medication: Simvastatin	1.3	1.9	8.8	0.6	-0.0	1.6	1.4	0.3	-0.0	0.4	-1.1	0.5	-0.1	0.5	2.1	1.2	1.5	0.9	0.5	1.5	1.0	3.0	2.7	1.0	1.4	2.5	1.6
Medication: Ibuprofen	1.3	1.5	3.3	1.4	1.0	1.4	1.5	1.1	1.2	1.4	0.5	1.3	1.0	1.2	1.2	-0.1	1.4	0.1	1.8	1.4	1.3	1.6	1.3	1.8	1.4	0.2	1.4
Suffer from ‘nerves’	1.3	2.0	3.4	1.8	1.6	1.6	1.6	1.6	1.4	1.6	1.5	1.6	1.5	1.7	1.5	-0.8	1.6	-1.4	1.6	1.6	0.8	0.8	1.1	1.3	1.6	-0.4	1.7
Hypertension (Self-reported)	1.3	3.7	9.2	-1.9	-2.5	-0.9	-1.4	-2.2	-2.4	-2.5	-2.9	-2.2	-2.6	-2.0	-0.4	-1.6	-1.2	0.2	-2.9	-1.2	-2.6	-0.7	0.0	-3.0	-1.3	2.4	-1.1
Allergy or Eczema	1.2	3.2	6.3	-1.7	-2.4	-1.4	-1.6	-2.3	-2.4	-2.3	-2.5	-2.2	-2.4	-2.2	-1.0	-1.7	-1.6	0.6	-1.9	-1.6	-2.3	-0.6	-1.2	-1.7	-1.6	0.7	-1.5
Lung FVC	1.2	6.3	9.3	-2.5	-2.4	-2.8	-2.9	-2.8	-2.5	-2.9	-2.1	-2.7	-2.5	-2.7	-3.1	-2.7	-3.0	0.6	-2.3	-2.9	-2.9	-2.6	-1.9	-2.1	-2.9	-1.2	-3.0
Frequency of depressed mood in last 2 weeks	1.2	1.6	4.4	2.1	1.4	1.4	1.4	1.4	1.3	1.4	1.3	1.3	1.3	1.4	1.2	-0.1	1.4	0.3	1.4	1.4	1.1	1.6	1.5	1.0	1.5	0.1	1.4
Hearing difficulty/problems: Yes	1.2	1.8	8.7	1.1	-0.1	1.8	1.5	0.1	-0.2	0.4	-0.9	0.5	-0.1	0.5	2.3	0.1	1.6	1.6	1.0	1.6	1.1	3.0	1.2	1.7	1.5	2.1	1.7
Current tobacco smoking	1.2	2.0	4.1	2.0	1.6	1.4	1.6	1.7	1.5	1.6	1.6	1.6	1.7	1.6	1.6	-0.3	1.6	0.3	1.0	1.6	1.0	0.8	1.9	0.8	1.7	0.1	1.6
Shortness of breath walking on level ground	1.2	1.4	7.4	1.3	0.0	1.7	1.4	0.4	0.0	0.4	-0.5	0.5	0.0	0.5	2.1	0.9	1.5	0.2	0.9	1.5	0.8	2.7	1.1	1.4	1.4	1.3	1.6
Number of full sisters	1.2	1.4	2.5	1.5	1.6	1.1	1.3	1.5	1.4	1.6	1.2	1.5	1.5	1.5	1.1	-0.6	1.2	-1.0	1.4	1.2	0.5	0.1	1.4	0.9	1.1	-0.5	1.1
Rheumatoid Arthritis	1.1	1.6	3.3	-1.4	-1.7	-0.9	-1.2	-1.7	-1.8	-1.6	-1.7	-1.6	-1.8	-1.5	-0.7	-1.2	-1.1	1.4	-1.2	-1.1	-0.3	0.3	-1.3	-0.6	-1.1	0.9	-1.0
Forced expiratory volume in 1-second (FEV1)	1.1	3.9	6.2	-2.5	-2.2	-1.8	-2.2	-2.4	-2.3	-2.4	-1.6	-2.3	-2.1	-2.4	-2.0	-1.9	-2.1	1.2	-2.1	-2.2	-1.8	-1.8	-1.0	-1.7	-2.2	0.4	-2.1
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.6	1.4	1.0	1.2	1.3	1.0	1.1	1.1	0.5	1.2	1.0	1.1	1.6	1.4	1.3	0.3	1.0	1.3	0.9	1.0	1.6	1.0	1.3	0.6	1.2
Forced vital capacity (FVC), Best measure	1.1	3.9	5.8	-2.4	-2.0	-2.0	-2.3	-2.2	-2.0	-2.3	-1.3	-2.2	-2.0	-2.2	-2.3	-2.3	-2.2	0.7	-2.0	-2.3	-2.4	-2.1	-1.0	-1.9	-2.3	-0.5	-2.2
Illnesses of father: Heart disease	1.1	1.5	2.5	-1.4	-1.5	-0.9	-1.0	-1.4	-1.5	-1.6	-1.4	-1.4	-1.5	-1.4	-0.5	-1.5	-0.9	1.3	-1.6	-1.0	-1.2	-0.7	-0.1	-1.6	-1.0	1.4	-0.8
Osteoporosis (self-reported)	1.1	1.4	5.6	0.9	0.6	1.5	1.3	0.8	0.7	1.0	-0.0	0.9	0.7	0.9	1.6	2.4	1.3	0.3	0.9	1.3	1.4	1.2	1.7	1.6	1.3	0.6	1.3
Supplements: Fish oil (including cod liver oil)	1.1	1.4	3.4	-1.2	-1.0	-1.4	-1.6	-1.1	-1.1	-1.1	-0.7	-1.3	-1.0	-1.2	-1.8	-0.3	-1.7	0.3	-1.1	-1.7	-1.0	-1.4	-0.9	-1.1	-1.4	-0.1	-1.6
Depressed Affect (Nagel 2018)	1.0	2.2	5.7	2.1	1.3	1.6	1.6	1.5	1.4	1.3	1.3	1.4	1.3	1.5	1.5	2.4	1.5	-0.4	1.7	1.5	1.3	1.2	1.3	1.8	1.6	-0.3	1.6
Prostate Cancer	1.0	1.4	2.8	1.7	1.1	1.5	1.4	1.2	0.9	1.2	0.9	1.2	1.2	1.2	1.6	0.8	1.4	0.5	1.2	1.4	1.1	0.8	1.1	1.4	1.4	0.2	1.4
Body mass index (BMI)	1.0	4.5	12.0	1.8	1.0	2.7	2.4	1.3	1.1	1.6	-0.1	1.6	0.9	1.4	3.1	1.6	2.5	1.6	1.9	2.5	3.4	3.5	1.4	3.1	2.4	2.4	2.5
Waist circumference	1.0	3.8	12.4	1.5	0.7	2.4	2.2	1.0	0.7	1.3	-0.2	1.2	0.6	1.2	3.0	1.4	2.3	1.7	1.4	2.3	3.0	3.5	2.0	2.4	2.3	2.8	2.4
Hair/balding pattern: Pattern 2	1.0	1.3	2.4	1.4	1.5	0.6	1.1	1.5	1.3	1.5	1.6	1.4	1.5	1.4	0.8	0.5	1.0	-1.0	1.5	1.1	0.8	0.5	0.4	1.4	1.1	-1.2	1.0
Falls in the last year	1.0	1.4	5.3	0.9	0.0	1.2	1.1	0.2	0.2	0.4	-0.5	0.4	-0.0	0.3	1.7	1.0	1.2	2.3	0.6	1.2	2.0	1.8	0.6	1.5	1.2	2.2	1.3
Peak expiratory flow (PEF)	1.0	2.2	3.7	-1.6	-1.8	-0.8	-1.5	-1.8	-1.9	-1.7	-1.7	-1.7	-1.7	-1.9	-1.0	-1.8	-1.4	1.9	-1.6	-1.4	-1.2	-0.9	-0.5	-1.4	-1.5	1.2	-1.3
Supplements: Vitamin C	1.0	1.2	1.8	-1.3	-1.3	-1.1	-1.0	-1.3	-1.1	-1.2	-1.3	-1.2	-1.2	-1.1	-1.0	-1.4	-1.0	0.8	-1.3	-1.1	-1.1	-1.0	-0.3	-0.8	-1.0	0.6	-1.1
Neuroticism (Nagel 2018)	0.9	2.0	3.4	1.8	1.7	1.3	1.6	1.7	1.6	1.4	1.8	1.5	1.4	1.8	1.3	1.4	1.5	-1.4	1.5	1.5	1.0	0.8	1.1	1.1	1.6	-0.5	1.6
HDL Cholesterol	0.9	1.4	4.1	1.3	1.4	1.2	1.2	1.2	1.4	1.5	1.3	1.2	1.3	1.4	0.8	1.8	1.0	0.4	1.0	1.1	2.0	0.9	0.8	1.2	1.1	0.3	1.0
Respiratory disease	0.9	2.0	3.8	1.7	1.2	1.6	1.7	1.3	1.1	1.7	1.0	1.4	1.0	1.5	1.9	-0.3	1.7	0.5	1.4	1.7	1.8	1.6	0.4	1.4	1.7	1.4	1.8
Average weekly spirits intake	0.9	1.2	2.2	1.3	1.4	0.8	1.1	1.3	1.4	1.5	1.3	1.3	1.4	1.4	0.8	-0.0	1.1	-1.0	1.2	1.1	0.7	0.6	0.7	1.0	1.1	-0.7	1.0
Vitamin and mineral supplements	0.9	1.2	2.0	1.3	1.3	0.9	1.1	1.3	1.3	1.3	1.0	1.3	1.4	1.3	1.1	1.1	1.1	-0.9	1.2	1.2	0.8	0.1	0.8	1.1	0.9	-1.1	1.0
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.3	-1.1	-1.2	-1.1	-1.2	-1.1	-1.1	-1.1	-1.1	-1.2	-1.2	-1.2	-0.8	0.0	-1.1	0.6	-1.5	-1.1	-1.3	-0.8	-0.9	-1.2	-1.2	-0.3	-1.1
Medication: Atenolol	0.9	1.1	5.4	-0.7	-0.3	-1.1	-1.2	-0.4	-0.3	-0.6	0.4	-0.8	-0.2	-0.6	-1.2	-1.6	-1.3	-1.4	-0.4	-1.2	-2.3	-1.3	1.0	-0.7	-1.2	-1.6	-1.1
Hearing difficulty/problems with background noise	0.9	1.5	3.4	1.3	0.9	1.5	1.5	1.0	0.8	1.1	0.4	1.1	0.8	1.2	1.8	0.6	1.5	-0.2	1.4	1.5	1.1	1.8	1.1	1.7	1.6	0.8	1.6
Had other major operations	0.9	1.0	2.6	-1.0	-0.8	-1.3	-1.2	-1.0	-0.5	-0.9	-0.9	-0.9	-0.8	-0.9	-1.3	-1.1	-1.2	0.3	-0.6	-1.2	-1.1	-1.6	-1.1	-0.6	-1.3	-1.2	-1.3
Pain all over the body in last month	0.9	1.0	2.9	-0.6	-0.8	-1.0	-1.1	-0.9	-0.9	-0.8	-0.6	-1.0	-0.8	-0.9	-1.2	-1.7	-1.1	0.3	-1.1	-1.1	-1.0	-1.2	-1.0	-0.9	-1.1	-0.7	-1.0
Medication: Cholesterol lowering	0.9	1.4	4.9	0.6	-0.2	1.2	1.0	0.1	-0.3	0.2	-0.8	0.2	-0.2	0.2	1.8	2.2	1.1	1.6	0.4	1.1	1.3	2.0	2.0	1.0	1.2	2.2	1.3
Glaucoma (self-reported)	0.9	1.1	3.5	-0.5	-1.2	-1.1	-1.0	-1.0	-1.4	-1.1	-1.1	-1.2	-1.1	-1.1	-1.1	0.1	-1.0	1.6	-1.2	-1.0	-1.9	-0.7	0.3	-1.1	-1.0	-0.2	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	10.4	-0.8	-0.9	-1.0	-1.0	-1.1	-0.9	-1.1	-0.9	-1.0	-0.9	-1.0	-0.7	-3.2	-0.9	-0.5	-0.6	-0.9	-1.7	-0.1	-0.9	-1.1	-1.1	-0.2	-1.0
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.4	-1.5	-0.9	-1.1	-1.1	-1.0	-0.8	-1.0	-0.7	-1.0	-1.0	-1.0	-1.0	0.9	-1.1	-0.7	-1.2	-1.1	-0.7	-1.4	-1.5	-1.2	-1.1	-0.1	-1.0
Back pain experienced in last month	0.9	1.3	2.4	1.5	1.2	1.1	1.5	1.2	1.4	1.3	0.7	1.4	1.1	1.4	1.4	0.9	1.5	-0.9	0.9	1.5	0.3	0.6	1.6	0.3	1.3	0.6	1.4
Smoking status: Current	0.9	1.5	3.4	1.8	1.4	1.3	1.4	1.4	1.3	1.4	1.5	1.3	1.5	1.3	1.3	-0.5	1.3	0.4	0.9	1.3	0.8	0.9	1.5	0.9	1.5	-0.3	1.4
Ulcerative Colitis	0.8	1.2	6.9	0.7	1.6	0.0	0.3	1.2	1.7	1.3	1.6	1.2	1.6	1.1	-0.4	-0.8	0.2	-1.6	1.2	0.2	-0.3	-1.3	0.3	0.4	0.1	-2.6	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	6.0	-0.5	-1.1	-0.8	-1.0	-1.1	-1.1	-1.2	-1.2	-1.2	-1.1	-1.2	-0.7	-2.4	-1.0	1.3	-0.9	-1.0	-1.2	-0.4	-1.1	-1.1	-1.0	0.0	-1.0
Illnesses of siblings	0.8	1.1	3.0	-1.7	-1.4	-0.8	-1.1	-1.2	-1.4	-1.3	-1.1	-1.2	-1.2	-1.4	-1.1	-0.7	-1.0	0.7	-1.0	-1.0	-0.5	0.1	-0.4	-0.2	-1.1	0.7	-1.0
Arm fat percentage (right)	0.8	3.3	10.0	1.6	0.8	2.2	2.1	1.1	0.9	1.4	-0.3	1.4	0.7	1.2	2.6	1.3	2.2	1.8	1.6	2.1	3.2	3.0	0.8	2.5	2.0	2.3	2.2
Birth weight of first child	0.8	1.5	3.5	-1.4	-1.8	-0.9	-1.1	-1.7	-1.7	-1.6	-1.9	-1.6	-1.8	-1.6	-0.5	-0.1	-1.0	1.5	-1.1	-1.0	0.1	0.8	-1.2	-0.1	-1.1	1.0	-1.0
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.4	-0.3	-1.3	-0.2	-0.6	-1.1	-1.3	-1.0	-1.1	-1.1	-1.4	-1.1	-0.4	-0.2	-0.5	1.5	-1.2	-0.5	0.1	0.7	-1.4	-1.1	-0.5	1.5	-0.4
Comparative body size at age 10	0.8	2.2	7.0	1.4	1.7	1.0	1.3	1.7	1.9	1.8	1.4	1.8	1.7	1.9	0.9	0.8	1.3	-1.2	2.0	1.3	2.0	0.5	0.3	2.6	1.1	-1.5	1.1
Migraine (self-reported)	0.8	1.0	3.1	1.1	0.5	1.6	1.1	0.5	0.6	0.8	-0.1	0.8	0.4	0.6	1.3	0.4	1.1	1.2	0.8	1.1	1.5	1.8	1.3	0.8	1.0	1.5	1.1
Handedness (chirality/laterality): Left-handed	0.8	1.0	2.7	0.8	0.2	1.4	1.2	0.5	0.2	0.3	-0.3	0.6	0.3	0.5	1.6	1.0	1.3	0.3	0.8	1.3	1.2	1.6	1.3	1.4	1.1	1.2	1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	2.3	-0.8	-1.4	0.1	-0.2	-1.1	-1.5	-1.2	-1.4	-1.1	-1.5	-1.1	0.4	0.6	-0.0	1.5	-0.4	-0.1	-0.1	0.9	-1.5	-0.1	-0.1	1.5	0.0
Arm fat mass (left)	0.8	3.2	9.3	1.4	0.6	2.3	2.0	1.0	0.7	1.2	-0.4	1.2	0.6	1.1	2.6	0.9	2.1	2.2	1.4	2.1	3.0	3.0	1.0	2.3	2.0	2.5	2.1
Mother’s age at death	0.8	1.0	4.0	-1.0	-0.5	-1.2	-1.0	-0.7	-0.4	-0.9	-0.1	-0.7	-0.6	-0.6	-1.2	-0.6	-1.1	-1.1	-0.6	-1.1	-0.8	-1.8	-2.0	-0.7	-1.0	-1.3	-1.1
Crohns Disease (2012)	0.7	1.2	2.7	-1.2	-0.7	-1.1	-1.4	-0.9	-0.8	-1.1	-0.4	-1.0	-0.9	-1.2	-1.0	-1.2	-1.3	-1.3	-1.0	-1.3	-1.6	-1.0	0.3	-1.5	-1.3	-0.4	-1.3
Neuroticism (2016)	0.7	1.1	4.0	1.1	1.6	0.6	0.7	1.6	1.3	1.4	2.0	1.3	1.6	1.2	0.2	0.1	0.8	-1.1	0.9	0.8	0.5	-0.2	0.6	0.4	0.7	-1.1	0.6
Triglycerides	0.7	1.1	2.7	1.0	0.5	1.4	1.4	0.7	0.7	0.7	-0.2	1.0	0.6	0.7	1.6	0.2	1.3	0.7	1.3	1.3	1.4	1.5	0.5	1.2	1.2	1.2	1.4
Sensitivity / hurt feelings	0.7	1.2	4.2	1.4	1.3	0.7	0.8	1.2	1.3	1.2	1.5	1.2	1.2	1.3	0.3	1.2	0.8	-1.8	1.4	0.8	-0.3	0.1	0.5	1.0	0.9	-2.0	0.8
Systolic blood pressure, automated reading	0.7	2.0	5.4	-1.3	-1.7	-0.4	-1.1	-1.6	-1.9	-1.8	-1.8	-1.6	-1.8	-1.8	-0.5	-1.4	-1.1	1.5	-2.0	-1.1	-1.5	-0.4	-0.3	-2.3	-1.0	1.6	-0.9
Angina	0.7	0.9	2.0	-0.7	-0.7	-1.3	-1.1	-0.9	-0.8	-0.9	-0.7	-1.0	-0.7	-0.8	-1.2	-0.9	-1.2	-0.6	-0.6	-1.2	-1.4	-1.3	-0.8	-0.6	-1.1	-1.0	-1.1
Medication for hormone replacement therapy	0.7	0.8	5.9	-0.4	-1.1	0.1	-0.5	-1.0	-1.2	-0.9	-1.2	-1.0	-1.1	-1.0	-0.1	-0.4	-0.4	2.4	-1.0	-0.5	-0.2	0.4	-0.2	-0.7	-0.4	1.5	-0.4
Average weekly fortified wine intake	0.7	0.8	4.2	-0.6	-0.2	-1.4	-0.8	-0.4	-0.1	-0.6	-0.1	-0.5	-0.2	-0.5	-1.3	-2.0	-0.9	-1.2	-0.3	-0.9	-1.1	-1.1	-0.4	-0.6	-0.8	-1.5	-0.9
Fluid intelligence score	0.7	1.5	2.4	-1.4	-1.2	-1.5	-1.5	-1.3	-1.3	-1.3	-0.8	-1.4	-1.1	-1.3	-1.5	-0.9	-1.6	1.0	-1.2	-1.6	-1.0	-0.8	-0.6	-0.9	-1.5	-0.3	-1.5
Mouth/teeth dental problems: Dentures	0.7	1.2	2.0	1.2	1.3	1.0	1.1	1.4	1.2	1.3	1.4	1.3	1.2	1.3	1.0	0.6	1.1	-0.9	0.9	1.2	0.5	1.0	1.4	0.5	1.2	0.1	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	4.0	-1.9	-1.4	-1.6	-1.8	-1.6	-1.4	-1.7	-0.6	-1.7	-1.3	-1.6	-1.9	-1.7	-1.8	0.3	-1.5	-1.8	-1.8	-2.0	-0.5	-1.4	-1.8	-0.7	-1.8
Pulse wave Arterial Stiffness index	0.7	0.8	2.1	-1.0	-1.2	-0.6	-0.8	-1.2	-1.2	-1.0	-1.4	-1.1	-1.3	-1.1	-0.6	-0.4	-0.8	0.8	-0.9	-0.8	-0.3	-0.2	-0.6	-0.6	-0.6	0.9	-0.7
Arm fat mass (right)	0.7	3.1	8.7	1.4	0.6	2.2	2.0	1.0	0.7	1.3	-0.3	1.2	0.6	1.1	2.6	0.8	2.1	1.9	1.3	2.0	3.0	2.9	1.1	2.3	1.9	2.4	2.1
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.5	-1.1	-0.8	-1.2	-1.1	-0.9	-0.8	-1.0	-0.3	-1.0	-0.7	-0.8	-1.2	-0.4	-1.1	-0.2	-0.8	-1.1	-1.1	-0.9	-0.6	-1.0	-1.1	-0.6	-1.1
Heart disease (mother)	0.7	0.8	1.6	-0.9	-1.2	-0.8	-0.8	-1.2	-1.1	-1.2	-1.3	-1.1	-1.2	-1.0	-0.7	0.9	-0.8	0.7	-1.1	-0.8	-0.6	-0.8	-0.9	-1.1	-0.9	0.4	-0.7
Arm fat percentage (left)	0.7	2.7	8.3	1.4	0.7	2.0	1.9	1.0	0.8	1.3	-0.3	1.3	0.7	1.2	2.4	1.0	1.9	1.7	1.5	1.9	2.9	2.7	0.6	2.3	1.8	2.1	2.0
Average weekly red wine intake	0.7	1.0	5.7	-1.4	-1.0	-0.8	-1.0	-1.0	-0.8	-1.3	-0.5	-1.1	-1.1	-1.1	-1.1	-0.2	-1.0	-0.3	-0.6	-1.0	-0.5	-1.1	-2.4	-0.7	-1.0	-0.1	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.3	-0.6	-1.1	-0.5	-0.7	-1.1	-1.2	-0.9	-1.3	-1.1	-1.2	-1.0	-0.7	-1.5	-0.7	1.5	-0.7	-0.8	0.3	-0.1	-0.4	-0.0	-0.7	0.5	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	3.6	-1.5	-0.6	-1.3	-1.5	-0.9	-0.6	-1.1	-0.1	-1.0	-0.6	-0.9	-1.8	-1.7	-1.5	0.1	-0.8	-1.5	-1.3	-1.9	-0.8	-0.8	-1.6	-1.6	-1.6
Verbal and Numeric Reasoning (VNR)	0.6	1.3	2.5	-1.6	-1.2	-1.2	-1.4	-1.3	-1.4	-1.3	-0.8	-1.4	-1.1	-1.3	-1.2	-1.3	-1.4	0.8	-1.1	-1.4	-0.5	-0.8	-1.2	-0.8	-1.4	0.2	-1.3
Lupus	0.6	1.0	3.5	-1.1	-1.0	-0.6	-0.9	-1.0	-1.1	-1.0	-0.8	-0.9	-1.2	-1.1	-0.8	-0.7	-0.8	0.4	-1.2	-0.8	-0.5	-0.7	-1.8	-1.9	-0.9	0.8	-0.8
Type 2 Diabetes (T2D) (2018)	0.6	1.1	2.4	-1.5	-1.4	-0.5	-0.9	-1.3	-1.4	-1.4	-1.4	-1.3	-1.3	-1.2	-0.6	-0.3	-0.9	0.5	-1.2	-0.9	-0.8	0.3	0.6	-1.1	-0.8	1.4	-0.8
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.4	1.2	0.5	0.8	0.9	0.7	0.6	0.7	0.2	0.6	0.5	0.7	1.3	0.1	1.0	0.7	0.7	1.0	1.6	1.5	-0.0	1.3	1.0	1.1	1.0
Ever had hysterectomy (womb removed)	0.6	0.7	2.9	-0.5	-1.2	-0.3	-0.3	-1.1	-1.3	-0.9	-1.7	-0.9	-1.1	-0.9	0.4	-0.9	-0.2	1.1	-0.9	-0.2	-0.4	0.5	0.1	-0.4	-0.3	1.2	-0.1
Severe depression (siblings)	0.6	0.7	1.5	-0.6	-0.7	-0.7	-0.9	-0.9	-0.7	-0.8	-0.7	-0.9	-0.8	-0.9	-0.8	0.8	-1.0	0.4	-0.8	-1.0	-1.2	-0.7	-0.8	-0.8	-0.9	-0.9	-1.0
Impedance of leg (right)	0.6	2.9	9.3	-1.7	-1.3	-2.1	-1.9	-1.4	-1.4	-1.5	-0.8	-1.6	-1.3	-1.6	-2.1	-1.5	-1.9	0.2	-2.2	-1.9	-2.4	-2.1	-1.2	-3.0	-1.8	-0.1	-1.9
Medication: Ramipril	0.6	0.8	3.4	-0.7	-1.0	-0.4	-0.7	-0.9	-1.1	-0.9	-1.2	-0.9	-1.2	-0.8	-0.5	-0.4	-0.6	0.1	-1.6	-0.6	-0.9	-0.7	-0.1	-1.8	-0.6	1.5	-0.5
Father’s age at death	0.6	0.8	7.6	-0.5	0.2	-0.2	-0.3	0.1	0.3	-0.1	0.3	0.1	0.4	-0.0	-0.6	-0.9	-0.3	-2.8	0.6	-0.3	-0.8	-1.1	-1.1	0.4	-0.5	-2.5	-0.5
Length of working week for main job	0.6	0.7	2.3	0.8	0.6	1.0	0.9	0.7	0.5	0.8	0.5	0.7	0.7	0.8	1.0	-0.1	1.0	0.7	0.4	1.0	1.3	0.4	0.9	0.6	0.8	1.5	0.9
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.9	-0.5	-1.1	-1.2	-0.9	-1.1	-1.2	-0.9	-1.0	-1.0	-1.0	-1.0	-0.5	-1.7	-0.8	0.4	-0.5	-0.8	-0.9	0.5	0.1	-0.3	-0.8	0.5	-0.8
Number of full brothers	0.6	0.8	2.8	-1.1	-0.6	-1.1	-0.8	-0.7	-0.6	-0.8	-0.5	-0.7	-0.6	-0.8	-0.7	-1.7	-0.8	-0.5	-0.8	-0.8	-1.3	-0.9	-1.0	-1.0	-0.9	-0.8	-0.8
Wheeze or whistling in the chest in last year	0.6	1.0	3.2	1.0	0.1	1.3	1.2	0.4	0.2	0.6	-0.2	0.5	0.1	0.5	1.8	0.2	1.2	0.4	1.3	1.2	0.7	1.7	1.3	1.6	1.2	1.0	1.4
Pulse wave peak to peak time	0.6	0.7	2.1	1.0	1.2	0.5	0.7	1.1	1.2	1.0	1.5	1.0	1.2	1.1	0.5	0.3	0.7	-0.8	0.8	0.7	0.2	0.1	0.6	0.5	0.5	-1.0	0.6
Whole body fat mass	0.6	2.3	6.5	1.3	0.5	2.0	1.7	0.8	0.6	1.1	-0.4	1.0	0.4	0.9	2.3	0.1	1.8	2.2	1.0	1.7	2.5	2.5	0.4	1.8	1.7	2.3	1.8
Overall health rating	0.6	1.2	3.6	1.9	0.6	1.3	1.3	0.7	0.8	0.9	-0.0	0.8	0.4	0.9	1.9	0.5	1.3	0.8	0.9	1.3	0.9	1.5	1.5	1.2	1.3	1.2	1.4
Age at last live birth	0.6	0.9	5.8	0.4	0.0	1.0	0.9	0.3	0.0	0.2	-0.3	0.4	0.1	0.3	1.3	2.4	1.0	0.4	0.4	1.0	1.7	1.6	-0.2	1.0	1.0	1.5	1.1
Medication: Aspirin	0.6	0.7	2.6	1.4	1.1	0.4	0.6	1.0	0.9	1.1	1.2	0.9	1.0	1.1	0.5	-0.7	0.6	-0.7	1.0	0.6	0.2	0.1	0.6	1.0	0.6	-1.6	0.6
Illnesses of siblings: Diabetes	0.6	0.8	1.7	-1.0	-1.0	-1.3	-1.0	-1.1	-0.8	-1.0	-1.2	-1.0	-0.9	-0.9	-0.9	0.0	-1.0	-0.1	-0.9	-1.0	-0.8	-0.9	-0.7	-0.8	-1.0	-0.4	-1.1
Commuting to job workplace: Walk	0.6	0.6	1.2	-0.8	-0.8	-0.8	-0.9	-0.8	-0.8	-0.7	-0.9	-0.9	-0.9	-1.0	-0.8	-0.3	-0.8	1.1	-1.0	-0.8	-0.7	-0.5	-0.9	-0.9	-0.9	-0.1	-0.9
Breast cancer (self-reported)	0.6	0.7	2.8	0.5	0.9	0.7	0.7	0.9	0.8	0.9	0.9	0.9	0.9	0.8	0.4	0.4	0.7	-0.8	1.0	0.7	0.7	0.6	1.7	1.0	0.7	0.7	0.7
Medication: Aspirin	0.6	0.8	2.2	1.4	1.1	0.4	0.6	1.1	1.0	1.1	1.2	0.9	1.1	1.1	0.5	-0.7	0.6	-0.8	1.0	0.7	0.1	0.2	1.1	0.9	0.6	-1.5	0.6
Illnesses of father: None of the above (group 1)	0.6	0.8	2.1	-0.8	-0.5	-1.0	-1.0	-0.7	-0.5	-0.6	-0.8	-0.6	-0.5	-0.7	-1.3	0.7	-1.1	-0.2	-0.8	-1.1	-0.8	-1.5	-1.2	-0.9	-1.0	-1.2	-1.2
Leg fat percentage (left)	0.6	2.0	6.2	1.0	0.2	1.9	1.5	0.6	0.4	0.9	-0.8	0.8	0.2	0.6	2.2	1.1	1.6	2.0	0.7	1.5	2.5	2.2	0.5	1.7	1.5	2.5	1.6
Fractured/broken bones in last 5 years	0.6	0.8	2.3	0.6	0.9	1.2	1.0	0.9	1.1	0.9	0.6	0.9	0.9	0.8	0.9	0.3	1.0	-0.1	1.1	1.0	0.8	1.2	1.5	1.1	0.9	-0.1	0.9
Ever depressed for a whole week	0.6	0.8	3.7	-0.3	-1.2	-0.2	-0.4	-1.0	-1.3	-1.0	-1.1	-1.0	-1.2	-0.9	0.2	-1.4	-0.3	1.9	-0.6	-0.3	-0.3	0.7	-1.0	-0.1	-0.4	1.0	-0.2
Pain experienced in last month	0.6	0.9	3.9	-2.0	-1.0	-1.2	-1.1	-1.0	-1.1	-1.3	-0.2	-1.1	-0.9	-1.1	-1.1	0.7	-1.1	-0.5	-0.9	-1.1	-1.0	-0.1	0.0	-0.4	-1.0	-0.6	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	1.9	0.8	0.8	0.7	0.9	0.8	0.7	1.0	0.6	0.9	0.6	0.8	1.0	1.4	0.9	-0.2	1.0	0.9	1.1	0.6	1.2	1.3	0.9	0.1	0.8
Alcohol drinker status: Previous	0.6	0.7	2.0	-0.6	-0.8	-0.8	-0.7	-0.8	-0.7	-0.7	-0.6	-0.8	-0.9	-0.7	-0.5	-1.4	-0.8	0.1	-1.2	-0.8	-1.3	-0.8	-0.3	-1.4	-0.7	0.4	-0.7
Leg fat mass (left)	0.6	2.2	7.2	1.0	0.2	1.9	1.6	0.6	0.3	0.9	-0.7	0.8	0.2	0.7	2.3	0.7	1.7	2.2	0.8	1.6	2.4	2.7	0.8	1.9	1.6	2.6	1.7
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.7	-1.7	-1.2	-1.3	-1.4	-1.4	-1.4	-1.4	-1.2	-1.4	-1.2	-1.3	-1.3	-1.1	-1.5	0.3	-1.0	-1.5	-0.3	-1.0	-2.2	-0.7	-1.4	-0.0	-1.4
Fasting Glucose	0.5	0.6	1.4	1.1	0.7	0.3	0.4	0.8	1.2	0.7	0.8	0.8	0.9	1.1	0.6	0.7	0.6	-1.2	1.0	0.6	0.0	0.1	0.9	0.8	0.7	-0.9	0.4
Primary Biliary Cirrhosis	0.5	0.8	1.5	-1.2	-0.8	-0.9	-1.0	-0.8	-0.8	-1.1	-0.9	-0.8	-0.8	-1.0	-0.6	0.0	-1.0	-0.7	-0.8	-1.0	-1.2	-1.2	-0.6	-0.9	-1.0	-0.7	-1.0
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.6	-1.1	-0.9	0.6	-0.1	-1.0	-0.9	-0.7	-1.6	-0.6	-1.1	-0.9	0.2	1.0	-0.1	0.9	-0.6	-0.1	0.4	0.9	-0.6	-0.1	-0.2	1.3	-0.1
BMI	0.5	2.6	9.5	0.6	0.2	2.2	1.8	0.5	0.3	0.6	-0.8	0.8	0.2	0.7	2.5	0.3	1.9	1.6	1.0	1.8	2.4	3.1	1.4	2.0	1.7	3.0	1.9
Multivitamins +/- minerals	0.5	0.6	1.4	-1.0	-0.9	-0.6	-0.9	-0.9	-0.9	-0.9	-0.5	-1.0	-0.9	-0.9	-1.1	-1.2	-1.0	0.6	-0.5	-1.0	-0.6	-0.1	-0.6	-0.7	-0.7	0.3	-0.9
Stomach or abdominal pain in last month	0.5	0.6	1.8	1.2	1.1	0.4	0.5	0.9	0.9	1.0	1.4	0.9	1.2	0.8	0.2	0.0	0.4	-0.6	0.5	0.4	-0.6	-0.3	1.0	-0.2	0.6	-1.0	0.4
Supplements: Glucosamine	0.5	0.6	4.0	0.3	-0.3	0.8	0.5	-0.2	-0.3	0.1	-0.7	-0.1	-0.2	-0.1	0.8	-0.6	0.5	1.9	0.1	0.5	0.9	1.5	0.6	0.4	0.6	2.0	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	4.0	0.3	1.4	-0.4	-0.1	1.0	1.5	1.0	1.5	1.0	1.3	1.0	-1.0	-2.0	-0.1	-1.7	0.7	-0.1	-0.1	-1.2	-0.3	-0.0	-0.3	-2.0	-0.4
Weight	0.5	2.6	7.2	1.3	0.5	2.2	1.8	0.8	0.5	1.1	-0.3	1.0	0.4	0.9	2.4	0.5	1.8	2.1	1.1	1.8	2.7	2.7	1.1	1.9	1.8	2.5	1.9
Qualifications: A levels/AS levels or equivalent	0.5	1.2	5.6	-0.6	0.4	-1.2	-0.9	0.0	0.4	-0.1	1.2	-0.1	0.3	0.1	-1.5	-0.8	-1.0	-2.4	-0.2	-0.9	-1.2	-2.1	-1.4	-1.2	-0.9	-1.9	-1.0
Prospective memory result	0.5	0.6	2.1	0.1	-0.1	1.2	1.0	0.2	0.1	0.1	-0.8	0.4	-0.1	0.3	1.3	0.3	1.1	0.4	0.4	1.1	0.6	1.4	0.3	0.6	0.9	1.3	1.1
Qualifications: O levels/GCSEs or equivalent	0.5	0.9	3.0	0.6	1.2	0.3	0.7	1.1	1.1	1.1	1.7	1.0	1.3	1.1	0.3	1.1	0.7	-1.2	1.3	0.7	0.2	-0.2	0.5	0.7	0.7	-1.2	0.7
Blood clot in the leg (DVT)	0.5	0.7	1.9	0.7	0.7	0.8	0.8	0.7	0.6	0.9	0.5	0.8	0.6	0.7	0.9	1.2	0.8	-0.1	1.0	0.8	1.0	0.7	1.4	1.2	0.9	0.2	0.8
Body fat percentage	0.5	1.9	5.6	1.1	0.3	1.8	1.5	0.6	0.4	0.9	-0.7	0.8	0.2	0.7	2.1	0.3	1.6	2.0	0.8	1.5	2.3	2.3	0.2	1.5	1.5	2.4	1.6
Exposure to tobacco smoke outside home	0.5	0.7	2.9	0.5	0.7	-0.5	-0.5	0.4	0.6	0.5	1.5	0.2	0.8	0.2	-1.0	-1.4	-0.6	-1.0	0.2	-0.6	-1.5	-0.9	0.7	-0.8	-0.4	-1.7	-0.5
Qualifications: College or University degree	0.5	1.7	7.1	1.3	1.8	1.1	0.7	1.6	1.6	1.5	2.7	1.4	2.0	1.4	0.2	-0.3	0.7	-1.8	1.4	0.7	1.2	-0.2	-0.5	1.0	0.7	-1.9	0.7
Angina (self-reported)	0.5	0.7	1.9	-0.5	-0.5	-1.2	-1.0	-0.7	-0.6	-0.7	-0.5	-0.8	-0.5	-0.6	-1.0	-0.8	-1.0	-0.8	-0.4	-1.0	-1.4	-1.2	-0.5	-0.4	-0.9	-1.2	-0.9
Qualifications: nursing, teaching	0.5	0.8	1.4	-1.0	-1.0	-0.9	-1.0	-1.1	-0.9	-1.2	-1.2	-0.9	-0.9	-1.1	-0.6	0.5	-1.0	-0.7	-1.0	-0.9	-0.7	-0.5	-1.1	-1.0	-1.0	0.5	-1.0
Eye problems/disorders: Cataract	0.5	0.6	2.2	0.1	0.4	1.1	0.9	0.4	0.5	0.5	0.0	0.6	0.3	0.5	1.2	0.4	0.9	-0.1	0.4	0.9	0.8	1.2	1.5	0.7	0.8	1.1	0.9
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.9	0.6	-0.0	0.8	0.7	0.2	-0.1	0.4	-0.2	0.2	0.1	0.2	1.2	0.8	0.8	0.5	0.2	0.8	0.8	1.1	0.9	0.5	0.9	2.0	0.9
Eye problems/disorders: Glaucoma	0.5	0.6	2.6	-0.3	-0.6	-0.6	-0.6	-0.6	-0.9	-0.6	-0.5	-0.7	-0.6	-0.7	-0.9	-0.5	-0.6	1.4	-0.9	-0.6	-1.6	-0.4	0.8	-1.0	-0.6	-0.2	-0.6
High cholesterol (Self-reported)	0.5	0.8	5.1	-0.4	-1.1	0.1	0.0	-0.8	-1.1	-0.7	-1.6	-0.8	-1.1	-0.7	0.6	0.4	0.1	1.6	-0.6	0.1	0.3	1.3	1.3	-0.0	0.1	2.3	0.2
Medication: Lisinopril	0.5	0.7	2.7	-1.0	-0.8	-0.7	-0.9	-0.8	-0.7	-1.0	-0.8	-0.8	-0.7	-0.8	-0.9	-0.9	-0.9	-0.6	-0.8	-0.9	-1.7	-0.7	0.5	-0.7	-1.0	-0.4	-1.0
Alcohol drinker status: Never	0.5	0.6	2.3	1.0	0.9	0.9	0.7	0.9	0.8	1.0	1.1	0.8	0.9	0.8	0.5	-0.2	0.6	0.4	0.7	0.6	1.5	0.3	0.4	1.1	0.7	-0.2	0.7
Ever smoked	0.5	0.9	3.3	-1.4	-0.9	-0.9	-0.9	-0.8	-0.9	-1.1	-0.7	-0.9	-0.8	-0.9	-1.2	-0.6	-0.9	-0.3	-1.1	-0.9	-1.8	-1.1	0.0	-0.9	-0.9	-1.0	-0.9
Commuting to job workplace: Cycle	0.5	0.6	1.5	1.0	0.7	0.8	1.0	0.7	0.6	0.7	0.6	0.8	0.6	0.7	1.2	0.1	1.0	0.0	0.9	1.0	0.6	0.8	0.4	0.6	0.9	0.6	1.0
Schizophrenia vs Biploar Disorder	0.4	0.5	1.3	-0.6	-0.8	-1.0	-0.5	-0.8	-0.6	-0.7	-1.1	-0.6	-0.7	-0.6	-0.3	-0.8	-0.5	1.0	-0.9	-0.5	-0.1	-0.2	-1.0	-0.8	-0.7	0.4	-0.7
Ulcerative Colitis (UC)	0.4	0.7	2.5	0.9	1.3	0.2	0.4	1.1	1.5	1.0	1.4	1.0	1.2	1.0	-0.1	-0.5	0.3	-0.9	0.8	0.3	0.1	-0.8	-0.1	0.3	0.2	-1.6	0.1
Ever used hormone-replacement therapy (HRT)	0.4	0.6	1.8	-0.7	-0.9	-0.5	-0.7	-0.9	-0.9	-0.7	-1.3	-0.8	-0.8	-0.8	-0.4	0.3	-0.7	0.5	-1.0	-0.7	-0.4	-0.5	-0.2	-1.1	-0.7	1.0	-0.7
Medication: Metformin	0.4	0.5	1.5	-1.2	-0.9	-0.2	-0.4	-0.9	-0.9	-0.8	-1.0	-0.6	-0.8	-0.7	-0.0	-0.5	-0.4	-0.1	-1.0	-0.4	-0.4	0.5	0.8	-0.9	-0.5	1.2	-0.4
Relative age voice broke	0.4	0.7	2.3	0.3	0.5	0.8	0.9	0.6	0.6	0.5	0.4	0.6	0.6	0.7	1.1	1.1	0.9	-0.7	0.7	0.9	0.9	1.2	1.5	1.0	0.9	0.6	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	2.4	0.4	1.4	-0.1	0.3	1.1	1.4	1.1	1.6	1.1	1.3	1.1	-0.6	-1.4	0.2	-1.3	0.7	0.3	0.4	-0.8	-0.1	0.2	0.0	-1.3	-0.0
Impedance of leg (left)	0.4	1.9	6.8	-1.2	-1.2	-1.6	-1.4	-1.2	-1.2	-1.2	-0.8	-1.3	-1.2	-1.3	-1.5	-1.2	-1.4	0.4	-1.9	-1.4	-2.0	-1.6	-0.9	-2.6	-1.4	0.4	-1.4
Trunk fat mass	0.4	1.7	5.6	1.1	0.2	1.7	1.4	0.6	0.3	0.8	-0.6	0.7	0.1	0.6	2.0	-0.2	1.4	2.2	0.6	1.4	2.2	2.1	0.1	1.2	1.4	2.4	1.5
Lung cancer (father)	0.4	0.5	3.4	0.5	0.5	-0.5	-0.2	0.2	0.6	0.5	0.6	0.3	0.5	0.3	-0.5	-0.8	-0.4	-0.6	0.1	-0.4	-1.4	-1.2	0.1	-0.6	-0.5	-1.9	-0.5
Tense / ‘highly strung’	0.4	0.7	2.4	1.3	1.1	0.3	0.6	0.9	0.9	0.9	1.3	0.8	1.0	0.9	0.2	-0.9	0.5	-0.8	1.0	0.5	-0.3	0.2	0.3	0.2	0.6	-1.6	0.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	3.6	-0.1	0.5	-1.0	-0.6	0.2	0.6	0.2	1.1	0.2	0.6	0.2	-1.4	-1.2	-0.7	-1.0	0.2	-0.7	-0.4	-1.6	-1.1	-0.2	-0.7	-1.9	-0.9
High blood pressure (siblings)	0.4	0.6	2.3	1.5	0.8	1.0	0.9	0.9	0.8	0.8	0.7	0.8	0.7	0.8	1.0	0.4	0.9	-0.2	0.7	0.9	0.1	-0.0	-0.2	0.3	1.0	-0.9	0.9
Leg fat percentage (right)	0.4	1.5	5.7	0.7	0.1	1.5	1.3	0.4	0.2	0.7	-0.7	0.6	0.1	0.5	1.8	0.9	1.3	2.0	0.5	1.3	2.2	2.1	0.4	1.4	1.2	2.4	1.4
Age at first live birth	0.4	0.6	4.9	0.0	-0.2	0.9	0.6	0.0	-0.3	-0.1	-0.5	0.1	-0.1	0.0	1.0	2.2	0.7	0.2	0.1	0.7	1.3	1.3	-0.6	0.5	0.6	1.5	0.8
Mouth/teeth dental problems: Loose teeth	0.4	0.5	1.5	0.8	1.2	0.4	0.4	1.0	1.2	1.1	1.0	1.0	1.1	0.9	0.1	-0.1	0.3	-0.2	0.7	0.3	0.4	-0.5	1.0	0.6	0.3	-0.5	0.3
Medication: Allopurinol	0.4	0.5	2.2	0.6	-0.0	1.1	0.5	0.1	-0.2	0.3	0.1	0.1	0.0	0.1	0.9	0.6	0.7	1.5	-0.1	0.6	0.5	0.9	1.4	0.2	0.7	1.4	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	4.0	-0.5	-0.5	-0.4	-0.5	-0.5	-0.7	-0.5	-0.5	-0.5	-0.3	-0.5	-0.3	-0.2	-0.5	0.4	-1.0	-0.5	-1.1	-0.1	2.0	-1.0	-0.4	0.7	-0.4
Leg fat mass (right)	0.4	1.7	6.5	0.7	0.0	1.7	1.3	0.4	0.1	0.7	-0.8	0.5	-0.0	0.4	2.0	0.5	1.4	2.2	0.6	1.3	2.1	2.4	0.7	1.5	1.3	2.6	1.5
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.8	0.9	0.6	0.8	0.7	0.7	0.5	0.6	0.9	0.6	0.6	0.6	0.7	-0.2	0.7	-0.6	0.2	0.7	0.1	0.3	1.3	-0.2	0.9	1.2	0.8
Mineral and other dietary supplements	0.4	0.5	1.0	0.7	0.7	0.6	0.8	0.7	0.7	0.6	0.6	0.8	0.6	0.8	1.0	1.0	0.9	-0.9	0.6	0.9	0.4	0.5	0.5	0.6	0.6	-0.6	0.9
Number of operations (self-reported)	0.4	0.5	1.7	-0.6	-0.5	-0.9	-0.8	-0.7	-0.4	-0.6	-0.6	-0.6	-0.6	-0.6	-1.1	-1.3	-0.9	0.5	-0.6	-0.9	-1.0	-0.7	0.1	-0.7	-0.9	-0.5	-0.9
Average weekly beer plus cider intake	0.4	0.5	1.6	0.9	1.1	0.3	0.6	0.9	1.1	1.0	0.8	1.0	1.0	0.9	0.5	-0.4	0.5	-1.3	-0.0	0.5	-0.3	-0.6	1.0	-0.5	0.5	-0.5	0.4
Unable to work because of sickness or disability	0.4	0.6	2.1	1.5	0.8	0.3	0.6	0.8	0.7	1.0	0.9	0.7	0.8	0.9	0.4	0.0	0.6	1.0	0.9	0.6	1.4	0.1	-0.1	1.0	0.7	-0.0	0.6
Cholesterol lowering medication	0.4	0.6	1.7	-0.9	-1.0	-0.7	-0.6	-0.9	-0.9	-0.9	-1.3	-0.9	-1.0	-0.7	-0.4	-0.7	-0.5	0.2	-0.7	-0.5	-1.2	0.6	0.8	-0.6	-0.6	0.5	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.0	0.6	-0.2	0.7	0.7	-0.0	0.1	0.1	-0.9	0.2	-0.1	0.1	1.3	-0.8	0.8	1.4	0.2	0.7	0.5	1.0	1.2	0.8	0.7	1.2	0.7
Supplements: Calcium	0.4	0.5	1.3	-1.0	-0.6	-0.9	-0.7	-0.7	-0.5	-0.7	-0.5	-0.6	-0.6	-0.5	-0.7	-0.8	-0.7	-0.1	-0.9	-0.7	-1.1	-0.4	-0.1	-0.9	-0.7	0.4	-0.7
Impedance of whole body	0.4	1.9	8.1	-1.0	-0.8	-1.8	-1.4	-0.9	-0.8	-1.0	-0.5	-1.0	-0.8	-1.0	-1.7	-1.7	-1.4	-0.2	-1.6	-1.4	-1.8	-2.2	-1.7	-2.8	-1.4	-0.1	-1.4
Worry (Nagel 2018)	0.3	0.6	1.2	1.1	0.8	0.7	0.9	0.8	0.5	0.7	0.9	0.8	0.6	0.9	0.8	-0.3	1.0	-1.0	0.5	1.0	0.1	0.7	0.5	0.0	1.0	0.0	1.0
Mean Putamen Volume	0.3	0.4	1.4	-0.9	-0.8	-0.7	-0.5	-0.8	-0.7	-0.5	-1.0	-0.7	-0.7	-0.7	-0.4	-0.2	-0.5	1.2	-0.5	-0.5	0.1	0.5	0.6	0.3	-0.5	0.3	-0.5
Smoking Status	0.3	0.7	3.6	-0.9	-0.9	-0.2	-0.5	-0.8	-0.8	-1.0	-1.1	-0.7	-0.7	-0.8	-0.5	-1.9	-0.4	1.3	-1.0	-0.4	-1.0	0.3	1.0	-0.8	-0.4	0.3	-0.4
Neuroticism	0.3	0.7	2.9	0.9	1.0	0.3	0.5	1.0	0.8	0.6	1.5	0.7	0.7	1.0	0.1	1.3	0.5	-1.7	0.8	0.5	-0.4	-0.3	0.1	0.1	0.6	-1.3	0.6
Supplements: Zinc	0.3	0.3	4.0	-0.1	0.4	0.1	0.0	0.2	0.3	0.3	0.5	0.3	0.4	0.3	-0.1	-2.0	-0.0	-0.5	0.5	-0.0	-1.1	-0.0	-0.2	0.0	-0.1	-1.1	-0.1
Diabetes (mother)	0.3	0.4	2.0	-0.3	-0.8	-0.4	-0.4	-0.7	-0.9	-0.6	-0.8	-0.7	-0.8	-0.7	-0.3	-0.0	-0.3	1.0	-0.8	-0.3	0.1	0.1	0.2	-0.5	-0.4	1.4	-0.3
Trunk fat percentage	0.3	1.3	5.3	1.0	0.1	1.4	1.2	0.4	0.2	0.6	-0.8	0.6	-0.0	0.4	1.8	-0.4	1.2	2.1	0.5	1.2	2.0	1.8	-0.4	0.9	1.2	2.3	1.3
Serious illness, injury or assault to yourself	0.3	0.4	2.2	-0.1	-0.5	0.3	0.1	-0.4	-0.5	-0.4	-0.8	-0.3	-0.4	-0.3	-0.0	-1.0	0.1	1.4	-0.2	0.1	-0.0	1.5	1.0	-0.1	0.1	1.4	0.1
Sitting height	0.3	2.1	4.8	-1.4	-1.2	-1.5	-1.6	-1.3	-1.3	-1.3	-0.5	-1.4	-1.2	-1.4	-1.8	-2.1	-1.6	0.7	-1.8	-1.6	-1.7	-1.9	-0.2	-2.2	-1.7	-0.0	-1.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	3.9	0.5	-0.5	0.1	0.0	-0.3	-0.4	-0.3	-0.5	-0.3	-0.3	-0.3	0.6	-2.0	0.1	0.9	0.1	0.1	0.1	0.8	-0.4	0.5	0.0	0.4	0.2
Diabetes (self-reported)	0.3	0.5	1.4	-1.0	-0.9	-0.3	-0.5	-0.9	-0.9	-0.8	-1.0	-0.8	-0.8	-0.6	-0.0	-0.2	-0.4	0.0	-0.8	-0.4	-0.7	0.7	1.2	-0.7	-0.5	1.0	-0.4
Asthma	0.3	0.5	2.1	1.2	0.6	0.8	0.8	0.5	0.5	0.9	0.5	0.6	0.5	0.7	0.9	-1.4	0.7	0.2	1.0	0.7	0.2	0.6	-0.0	0.4	0.8	0.2	0.8
Medication: Lansoprazole	0.3	0.4	1.2	0.4	0.6	0.2	0.6	0.6	0.5	0.5	0.4	0.6	0.5	0.6	0.8	0.3	0.6	-1.0	0.5	0.6	0.7	0.8	1.1	1.0	0.5	0.2	0.6
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.9	-0.1	-0.5	-0.8	-0.8	-0.6	-0.4	-0.7	-0.4	-0.6	-0.6	-0.7	-0.7	-1.4	-0.8	-0.1	-0.6	-0.8	-0.5	-0.6	-0.7	-0.3	-0.9	-0.4	-0.9
Gout (self-reported)	0.3	0.4	1.8	-0.2	-0.8	0.2	-0.4	-0.7	-1.0	-0.6	-0.7	-0.8	-0.7	-0.8	0.1	-1.3	-0.3	1.3	-0.7	-0.3	-0.8	-0.1	0.1	-0.6	-0.4	0.8	-0.2
Health satisfaction	0.3	0.4	2.5	0.2	-0.7	0.2	-0.1	-0.6	-0.5	-0.4	-1.0	-0.5	-0.9	-0.6	0.4	-0.9	-0.1	0.6	-0.4	-0.1	0.2	0.8	-1.2	-0.3	-0.1	1.6	-0.0
Medication: Blood pressure	0.3	0.6	2.8	0.5	-0.2	1.2	0.7	0.1	-0.2	-0.0	-0.7	0.1	-0.3	0.1	1.4	0.3	0.8	0.3	-0.2	0.8	-0.2	1.5	1.2	-0.2	0.8	1.7	1.0
Leg pain on walking	0.3	0.3	3.1	0.3	-0.1	0.5	0.3	-0.1	-0.1	0.0	-0.4	-0.0	-0.3	-0.1	0.5	0.0	0.3	0.5	0.2	0.3	1.4	0.9	-1.0	0.5	0.2	1.8	0.4
Leg fat-free mass (right)	0.3	1.5	3.5	1.2	0.6	1.8	1.4	0.8	0.6	1.0	0.3	0.9	0.7	0.9	1.7	-0.1	1.4	1.3	1.1	1.4	1.9	1.9	0.7	1.6	1.4	1.2	1.5
Diabetes diagnosed by doctor	0.3	0.5	1.7	-1.3	-0.7	-0.5	-0.7	-0.8	-0.8	-0.8	-0.6	-0.7	-0.7	-0.6	-0.5	-0.4	-0.7	-0.4	-0.9	-0.7	-0.8	0.2	0.5	-0.9	-0.7	0.6	-0.6
Friendships satisfaction	0.3	0.3	2.4	-0.6	-0.6	-0.3	-0.5	-0.6	-0.5	-0.7	-0.4	-0.7	-0.7	-0.7	-0.3	-1.6	-0.5	0.2	-0.4	-0.5	-0.7	0.0	0.0	-0.5	-0.6	0.3	-0.5
Asthma (self-reported)	0.3	0.5	1.7	1.3	0.6	0.8	0.8	0.6	0.5	0.9	0.5	0.6	0.5	0.7	0.8	-1.3	0.7	0.1	1.2	0.7	0.3	0.7	0.0	0.6	0.8	0.2	0.8
Leg predicted mass (right)	0.3	1.5	3.8	1.2	0.6	1.8	1.4	0.8	0.6	1.0	0.2	0.9	0.7	0.9	1.7	-0.0	1.4	1.4	1.1	1.4	1.9	1.9	0.8	1.7	1.4	1.2	1.5
Number of self-reported non-cancer illnesses	0.3	0.5	2.8	-0.0	-0.8	0.1	0.1	-0.6	-0.6	-0.6	-1.4	-0.5	-1.0	-0.4	0.9	-1.5	0.1	0.8	-0.5	0.1	-0.1	0.5	0.6	-0.3	0.1	1.7	0.1
Financial situation satisfaction	0.3	0.4	1.2	0.9	0.3	0.6	0.7	0.3	0.6	0.4	-0.3	0.5	0.3	0.5	0.9	0.0	0.7	0.7	0.3	0.7	0.9	0.8	0.1	0.2	0.6	1.1	0.7
Illnesses of father: High blood pressure	0.3	0.3	4.0	-0.3	-0.4	0.0	-0.3	-0.4	-0.4	-0.4	-0.3	-0.4	-0.3	-0.5	-0.2	-2.0	-0.2	0.5	-0.6	-0.2	-0.9	0.1	0.8	-0.7	-0.4	0.5	-0.3
Risk taking	0.3	0.4	5.4	-0.4	-0.2	0.5	0.1	-0.2	-0.3	-0.2	-0.2	-0.1	-0.2	-0.3	0.1	-2.3	0.1	-0.1	-0.1	0.1	-0.8	0.9	1.3	-0.3	0.1	0.9	0.1
Myopia	0.3	0.4	1.4	-0.5	-0.7	-0.9	-0.8	-0.7	-0.6	-0.7	-0.6	-0.7	-0.7	-0.6	-0.7	-0.3	-0.8	0.7	-0.4	-0.8	-0.1	-0.5	-1.2	-0.4	-0.8	-0.1	-0.8
Alzheimer’s Disease (including proxy)	0.2	0.3	1.3	0.7	0.3	0.4	0.5	0.3	0.2	0.5	0.2	0.4	0.4	0.3	1.0	0.6	0.5	-0.2	0.4	0.5	0.7	0.6	1.1	0.6	0.5	0.7	0.5
Irritable Bowel Disease (IBD)	0.2	0.5	1.5	-0.2	0.1	-0.7	-0.8	-0.1	0.3	-0.2	0.5	-0.2	-0.0	-0.3	-1.0	-0.5	-0.9	-0.9	-0.3	-0.8	-1.0	-1.2	-0.4	-0.9	-0.9	-1.1	-1.0
Major Depression (MDD)	0.2	0.3	3.4	0.2	-0.1	0.5	0.4	0.1	-0.1	-0.0	0.0	0.1	0.1	0.2	0.9	-0.6	0.4	0.1	-0.1	0.4	0.4	0.7	0.4	-0.7	0.4	1.8	0.4
Age at First Birth	0.2	0.3	2.8	0.1	-0.2	0.4	0.3	-0.1	0.2	0.0	-0.3	0.1	-0.1	0.3	0.6	0.2	0.4	0.6	0.2	0.4	1.1	0.5	-0.1	0.1	0.4	1.7	0.5
Heel T-Score	0.2	1.5	5.1	0.7	1.9	-0.2	0.1	1.5	1.9	1.6	2.3	1.5	1.9	1.4	-1.0	-0.8	-0.1	-1.5	0.8	-0.0	0.2	-1.9	0.2	-0.1	-0.2	-2.1	-0.3
Lung FEV1/FVC ratio	0.2	1.2	4.5	0.7	1.7	0.3	0.5	1.5	1.6	1.5	2.1	1.2	1.8	1.4	0.0	-1.0	0.6	-1.2	0.8	0.6	1.2	-0.7	1.1	0.3	0.6	-0.7	0.4
Chronotype (morning person)	0.2	0.5	2.3	0.5	0.9	-0.0	0.2	0.8	0.7	0.8	1.1	0.6	0.9	0.7	-0.3	1.5	0.1	-1.4	0.6	0.1	0.9	-0.6	-0.4	0.6	0.2	-0.3	0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	1.5	0.4	0.7	0.4	0.3	0.5	0.5	0.7	1.0	0.5	0.7	0.6	0.0	-0.4	0.2	-0.5	0.1	0.2	0.4	-0.1	1.2	0.1	0.3	0.1	0.3
Leg fat-free mass (left)	0.2	0.9	2.5	0.7	0.3	1.4	1.0	0.5	0.3	0.7	0.1	0.6	0.3	0.5	1.3	-0.3	1.0	1.5	0.7	1.0	1.6	1.6	0.5	1.3	1.0	1.1	1.1
Hand grip strength (right)	0.2	0.5	1.9	-0.7	-0.4	-0.2	-0.7	-0.5	-0.5	-0.5	0.0	-0.5	-0.3	-0.6	-0.9	-0.5	-0.7	-0.8	-0.7	-0.7	-1.4	-1.3	-0.3	-1.2	-0.7	-0.5	-0.7
Age when periods started (menarche)	0.2	0.5	1.9	-0.5	0.2	-0.6	-0.6	0.1	0.2	-0.1	0.9	-0.2	0.2	-0.0	-0.9	-1.4	-0.7	-1.3	-0.1	-0.7	-1.1	-1.0	0.1	-0.7	-0.6	-0.8	-0.6
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	2.1	0.3	-0.1	0.4	0.3	-0.1	-0.0	-0.1	-0.6	0.0	-0.1	0.0	0.6	0.2	0.2	-0.3	-0.1	0.2	-0.2	0.6	1.4	-0.2	0.2	1.4	0.3
Leg predicted mass (left)	0.2	1.0	2.9	0.8	0.4	1.4	1.1	0.5	0.4	0.7	0.1	0.6	0.4	0.6	1.3	-0.3	1.1	1.5	0.8	1.1	1.7	1.7	0.5	1.3	1.0	1.2	1.2
Nervous feelings	0.2	0.4	2.4	-0.2	-0.2	-0.6	-0.4	-0.3	-0.2	-0.5	-0.2	-0.3	-0.4	-0.3	-0.6	-0.8	-0.4	-0.7	-0.6	-0.4	-1.5	-0.6	-0.6	-1.2	-0.5	-0.7	-0.4
Mouth/teeth dental problems	0.2	0.3	1.9	-0.7	-0.4	-0.4	-0.4	-0.4	-0.5	-0.4	-0.5	-0.4	-0.5	-0.5	-0.6	0.4	-0.5	-0.4	-0.2	-0.4	-0.4	-0.8	-1.4	-0.4	-0.4	-0.7	-0.4
Neuroticism score	0.2	0.5	1.5	1.2	0.6	0.7	0.7	0.7	0.5	0.4	0.9	0.5	0.5	0.7	0.5	1.0	0.7	-0.4	0.8	0.7	-0.1	0.5	0.5	0.5	0.8	-0.7	0.8
Alcohol intake versus 10 years previously	0.2	0.3	3.4	-0.2	-0.4	0.1	-0.0	-0.4	-0.3	-0.2	-0.7	-0.3	-0.5	-0.3	0.3	0.2	0.0	0.7	-0.3	0.0	0.9	0.2	-0.5	-0.4	0.0	1.8	0.1
Worrier / anxious feelings	0.2	0.3	1.0	-0.1	-0.5	-0.9	-0.5	-0.4	-0.5	-0.7	-0.1	-0.5	-0.5	-0.3	-0.5	-0.3	-0.4	-1.0	-0.5	-0.4	-0.9	-0.6	-0.4	-0.4	-0.4	-1.0	-0.4
Noisy workplace	0.2	0.3	0.7	-0.6	-0.4	-0.6	-0.5	-0.3	-0.5	-0.4	0.1	-0.6	-0.3	-0.5	-0.3	0.8	-0.5	0.5	-0.7	-0.5	-0.5	-0.6	-0.6	-0.8	-0.4	-0.6	-0.4
Illnesses of mother	0.2	0.2	1.1	-0.8	0.3	-0.5	-0.4	0.0	0.4	0.1	0.4	0.1	0.3	0.1	-0.7	-0.7	-0.4	-0.8	-0.2	-0.4	-0.1	-0.5	-0.5	-0.4	-0.5	-1.1	-0.5
Impedance of arm (left)	0.2	0.9	4.3	-0.5	-0.3	-1.4	-0.9	-0.4	-0.2	-0.5	0.0	-0.5	-0.3	-0.4	-1.3	-1.2	-1.0	-0.5	-0.9	-1.0	-1.1	-1.9	-1.6	-2.1	-0.9	-0.5	-1.1
Standing height	0.2	2.2	7.7	-1.3	-1.3	-1.3	-1.5	-1.3	-1.3	-1.2	-0.6	-1.4	-1.2	-1.4	-1.5	-2.8	-1.5	1.5	-1.9	-1.5	-1.5	-1.7	-0.7	-2.6	-1.5	0.5	-1.4
Exposure to tobacco smoke at home	0.2	0.3	1.2	0.5	0.2	0.3	0.3	0.2	-0.1	0.4	0.3	0.2	0.3	0.3	0.6	-1.0	0.4	1.1	-0.0	0.4	0.5	0.6	0.6	-0.1	0.4	0.9	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.3	1.0	0.4	0.3	0.6	0.4	0.5	0.4	0.2	0.5	0.4	0.5	0.7	-0.9	0.6	-0.5	1.1	0.6	0.2	0.7	0.1	1.1	0.6	-0.4	0.6
Loud music exposure frequency	0.2	0.2	1.4	0.3	-0.1	0.7	0.3	-0.1	-0.3	-0.1	0.0	0.0	-0.2	-0.2	0.6	0.2	0.4	0.2	0.2	0.4	-0.2	1.2	0.6	0.6	0.5	-0.1	0.5
Medication: Amlodipine	0.2	0.3	2.9	0.4	0.1	0.8	0.4	0.3	0.1	0.2	0.1	0.2	0.1	0.2	0.4	-0.3	0.5	0.3	-0.1	0.5	-0.5	0.5	1.7	-0.4	0.4	0.8	0.5
Eye problems/disorders: None of the above	0.2	0.2	0.9	-0.4	-0.3	-0.7	-0.6	-0.3	-0.3	-0.4	-0.1	-0.4	-0.2	-0.4	-0.7	-0.3	-0.6	-0.2	0.1	-0.6	-0.3	-0.2	-0.9	0.2	-0.5	-0.9	-0.6
Neck or shoulder pain in last month	0.2	0.2	1.6	0.9	0.0	0.5	0.4	0.1	0.1	0.5	-0.3	0.2	0.1	0.2	0.6	-0.6	0.4	1.3	0.2	0.4	0.1	0.4	0.2	-0.1	0.3	0.9	0.4
Medication: Omeprazole	0.2	0.3	2.9	0.1	-0.3	0.2	0.3	-0.3	0.0	-0.2	-1.1	-0.0	-0.2	-0.1	0.8	-1.7	0.3	0.8	-0.2	0.3	-0.3	0.2	0.4	-0.0	0.2	0.4	0.2
Had major operations	0.2	0.2	0.8	-0.4	-0.6	-0.2	-0.2	-0.6	-0.5	-0.5	-0.9	-0.4	-0.6	-0.5	-0.2	-0.7	-0.2	0.5	-0.4	-0.2	-0.4	0.5	-0.3	-0.8	-0.3	0.7	-0.2
Whole body fat-free mass	0.2	0.9	2.9	0.7	0.2	1.4	0.9	0.4	0.1	0.6	0.1	0.4	0.3	0.4	1.2	0.0	0.9	1.7	0.6	0.9	1.5	1.7	1.0	1.3	0.9	1.2	1.1
Loneliness, isolation	0.2	0.2	1.0	0.0	-0.6	0.0	-0.3	-0.5	-0.7	-0.6	-0.3	-0.6	-0.6	-0.5	-0.3	-0.8	-0.3	0.5	-0.2	-0.3	0.4	0.8	0.3	0.4	-0.3	1.0	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	2.3	-0.5	-0.6	-0.3	-0.2	-0.5	-0.6	-0.5	-0.4	-0.5	-0.5	-0.4	-0.1	0.8	-0.2	1.1	-0.8	-0.3	0.1	-0.2	0.1	-0.5	-0.3	1.5	-0.2
Whole body water mass	0.2	1.0	3.1	0.8	0.4	1.4	1.0	0.5	0.3	0.7	0.3	0.6	0.4	0.6	1.3	-0.1	1.0	1.5	0.8	1.0	1.6	1.8	1.2	1.4	1.1	1.1	1.2
Average weekly champagne plus white wine intake	0.2	0.3	0.6	-0.6	-0.4	-0.5	-0.6	-0.5	-0.4	-0.5	-0.4	-0.4	-0.4	-0.5	-0.7	-0.8	-0.6	-0.3	-0.7	-0.6	-0.5	-0.8	-0.5	-0.5	-0.8	-0.4	-0.7
Ever taken oral contraceptive pill	0.2	0.2	1.1	-0.4	-0.8	-0.1	-0.1	-0.6	-0.7	-0.6	-1.1	-0.5	-0.6	-0.5	0.2	-1.0	0.0	0.4	-0.3	-0.0	-0.3	0.5	-0.6	-0.3	-0.2	0.3	-0.0
Basal metabolic rate	0.2	1.2	3.6	0.8	0.3	1.5	1.1	0.5	0.3	0.7	0.0	0.6	0.3	0.5	1.5	-0.1	1.1	1.8	0.7	1.1	1.7	1.9	1.0	1.4	1.1	1.4	1.3
Arm fat-free mass (left)	0.2	1.1	4.0	0.6	0.0	1.5	1.1	0.3	-0.0	0.5	-0.3	0.4	0.1	0.3	1.5	-0.2	1.1	1.9	0.5	1.1	1.7	2.0	1.1	1.3	1.0	1.9	1.2
Irritability	0.2	0.4	3.2	-0.4	0.4	-0.6	-0.3	0.3	0.4	0.0	0.8	0.1	0.2	0.2	-0.6	0.1	-0.4	-1.8	0.1	-0.4	-1.0	-0.9	0.0	-0.4	-0.3	-1.3	-0.4
Basal cell carcinoma (self-reported)	0.2	0.3	0.7	-0.4	-0.7	0.0	-0.4	-0.6	-0.9	-0.7	-0.3	-0.7	-0.7	-0.6	-0.2	-0.5	-0.3	0.8	-0.7	-0.3	-0.2	-0.1	0.1	-0.4	-0.3	0.7	-0.2
Arm predicted mass (left)	0.2	1.2	3.8	0.7	0.1	1.6	1.1	0.3	0.1	0.5	-0.2	0.5	0.1	0.4	1.6	-0.1	1.2	1.9	0.5	1.1	1.7	1.9	1.1	1.3	1.1	1.8	1.3
Reaction Time	0.1	0.2	0.8	-0.1	-0.1	0.5	0.4	-0.1	-0.1	-0.2	-0.2	0.1	-0.1	-0.0	0.4	-0.4	0.4	0.2	0.6	0.4	0.3	0.6	-0.5	0.9	0.3	-0.5	0.4
Breast Cancer	0.1	0.2	0.9	0.2	-0.1	0.8	0.5	0.1	-0.1	-0.0	-0.2	0.1	-0.1	0.1	0.8	-0.5	0.6	0.7	0.2	0.6	-0.0	0.9	-0.4	0.6	0.6	0.1	0.7
Body Mass Index (BMI) (2010)	0.1	0.1	0.8	-0.0	-0.2	0.6	0.3	-0.1	-0.3	-0.3	-0.5	-0.1	-0.2	-0.2	0.5	0.2	0.2	-0.2	0.1	0.2	0.0	0.8	0.8	0.1	0.3	0.9	0.4
Coronary Artery Disease (CAD)	0.1	0.1	2.1	0.0	0.1	0.1	-0.0	-0.1	-0.1	-0.1	0.0	-0.1	0.0	-0.2	-0.6	-1.5	-0.2	0.1	-0.2	-0.1	-0.1	-0.1	0.5	-0.3	-0.2	0.1	-0.0
Blood Red Count	0.1	0.7	5.7	-0.1	-0.9	0.1	0.2	-0.5	-0.8	-0.5	-1.3	-0.5	-1.0	-0.6	0.9	0.8	0.2	2.4	-0.1	0.2	0.9	1.1	-0.8	0.4	0.1	1.7	0.2
Blood White Count	0.1	0.4	1.7	0.7	0.3	0.5	0.6	0.5	0.6	0.3	0.3	0.4	0.1	0.5	1.1	-0.7	0.7	-0.9	0.8	0.7	-0.2	1.3	0.7	0.3	0.7	0.3	0.8
Height	0.1	1.5	12.1	-0.7	-0.8	-0.9	-1.0	-0.8	-0.7	-0.7	-0.3	-0.9	-0.7	-0.9	-1.2	-3.5	-1.1	1.2	-1.4	-1.1	-1.1	-1.6	0.5	-2.2	-1.0	0.6	-1.0
Waist Hip Ratio (WHR)	0.1	0.5	1.5	-0.9	-0.8	-0.8	-0.6	-0.8	-0.8	-0.8	-0.6	-0.8	-0.8	-0.9	-0.4	-0.7	-0.5	0.4	-0.9	-0.5	-0.6	0.2	0.9	-1.2	-0.5	1.0	-0.4
Hair Pigment	0.1	1.5	3.8	1.0	0.4	1.7	1.6	0.7	0.8	0.8	-0.5	0.9	0.4	0.8	2.0	1.4	1.7	0.8	0.8	1.6	1.7	1.7	1.0	0.8	1.5	1.8	1.6
Hand grip strength (left)	0.1	0.3	0.7	-0.7	-0.6	-0.0	-0.6	-0.5	-0.8	-0.7	-0.3	-0.6	-0.3	-0.7	-0.7	-0.2	-0.5	0.3	-0.6	-0.5	-0.8	-0.8	-0.3	-0.7	-0.5	-0.2	-0.5
Relative age of first facial hair	0.1	0.1	1.1	0.1	0.0	0.1	-0.0	-0.0	-0.0	-0.1	0.4	-0.1	0.1	0.0	-0.1	-0.3	0.0	-0.3	0.2	-0.0	-0.6	0.4	1.0	0.3	0.1	-0.6	-0.0
Maternal smoking around birth	0.1	0.2	0.9	0.1	0.1	-0.4	-0.4	-0.0	0.1	0.1	0.6	-0.2	0.0	-0.2	-0.4	0.9	-0.5	0.6	0.1	-0.5	-0.2	0.1	1.0	0.2	-0.5	-0.5	-0.5
Medication: Levothyroxine sodium	0.1	0.2	0.8	-0.2	0.2	-0.3	-0.4	0.1	0.2	-0.1	0.7	-0.1	0.1	0.0	-0.6	0.2	-0.4	-0.9	-0.1	-0.4	-0.6	-0.6	0.9	-0.2	-0.3	-0.5	-0.4
Chronic bronchitis/emphysema (father)	0.1	0.1	1.1	0.0	0.2	0.0	-0.0	0.2	0.2	0.1	0.5	0.0	0.1	0.2	0.1	-1.0	-0.0	-0.5	0.2	-0.0	0.0	0.4	0.5	0.1	0.0	0.0	0.0
High blood pressure (mother)	0.1	0.2	0.7	0.2	-0.6	0.4	0.2	-0.3	-0.6	-0.4	-0.8	-0.3	-0.6	-0.3	0.5	0.1	0.3	-0.1	0.1	0.3	-0.8	0.3	-0.1	0.4	0.2	0.3	0.3
Number of incorrect matches in round	0.1	0.2	1.7	-0.2	0.0	-0.4	-0.2	-0.1	0.1	0.0	-0.1	0.0	0.0	0.0	-0.3	-1.3	-0.2	-0.3	-0.1	-0.2	-0.7	-0.7	-0.0	-0.5	-0.1	-1.0	-0.3
Alcohol usually taken with meals	0.1	0.1	0.6	0.2	0.2	0.2	0.2	0.2	0.1	0.1	0.4	0.2	0.2	0.2	0.1	0.4	0.2	0.1	0.0	0.2	0.7	0.1	-0.7	-0.1	0.2	0.8	0.2
Had menopause	0.1	0.1	0.3	0.2	0.2	0.0	0.3	0.2	0.1	0.2	0.1	0.2	0.1	0.4	0.1	-0.3	0.3	-0.0	0.3	0.3	0.2	0.1	0.5	0.6	0.2	-0.0	0.3
Financial difficulties in last 2 years	0.1	0.2	0.7	-0.1	-0.5	-0.1	0.0	-0.6	-0.4	-0.3	-0.7	-0.3	-0.4	-0.3	0.5	-0.9	0.1	0.8	-0.1	0.1	-0.1	0.7	0.3	-0.2	-0.1	0.8	0.0
Heart attack	0.1	0.1	1.0	0.1	-0.4	0.1	0.1	-0.4	-0.1	-0.3	-0.8	-0.2	-0.3	-0.1	0.4	0.4	0.1	1.0	-0.0	0.1	0.0	0.5	0.6	0.4	-0.1	0.3	0.1
Allergy	0.1	0.3	2.1	-0.2	0.6	-0.1	0.0	0.5	0.7	0.3	0.8	0.4	0.8	0.5	-0.4	1.4	0.1	-0.7	0.0	0.1	0.4	-0.3	0.4	0.2	-0.0	-0.9	-0.0
Impedance of arm (right)	0.1	0.6	3.2	-0.3	-0.2	-1.2	-0.7	-0.3	-0.2	-0.4	-0.0	-0.4	-0.2	-0.3	-1.1	-0.8	-0.7	-0.0	-0.8	-0.7	-0.8	-1.4	-1.1	-1.8	-0.7	-0.2	-0.8
Trunk fat-free mass	0.1	0.6	2.3	0.4	0.1	1.0	0.6	0.2	0.0	0.4	0.2	0.3	0.2	0.3	0.8	0.2	0.6	1.5	0.4	0.6	1.2	1.4	1.4	1.1	0.7	0.8	0.8
Pulse rate	0.1	0.2	1.2	-0.3	-0.5	-0.0	0.3	-0.4	-0.2	-0.4	-1.1	-0.1	-0.8	-0.2	0.4	0.6	0.2	-0.4	-0.0	0.2	-0.2	0.8	-0.7	0.2	-0.0	0.2	0.2
Happiness	0.1	0.1	1.2	0.5	0.2	0.1	0.1	0.1	0.3	0.1	0.2	0.1	0.0	0.1	0.1	-0.7	0.1	-0.0	0.4	0.0	0.4	0.3	-1.1	0.2	0.0	-0.0	0.1
Depression (self-reported)	0.1	0.1	2.0	0.1	-0.1	-0.3	-0.3	-0.2	-0.1	-0.2	0.0	-0.3	-0.3	-0.2	-0.1	-1.4	-0.2	-0.1	0.2	-0.2	-0.3	0.0	-0.4	-0.1	-0.2	-0.3	-0.2
Trunk predicted mass	0.1	0.5	2.3	0.4	0.0	1.0	0.6	0.2	-0.0	0.4	0.1	0.2	0.1	0.2	0.8	0.2	0.6	1.5	0.3	0.6	1.2	1.4	1.3	1.1	0.6	0.8	0.7
Pulse wave reflection index	0.1	0.1	0.6	0.3	0.3	0.1	0.1	0.3	0.2	0.2	0.2	0.3	0.5	0.2	0.1	-0.8	0.1	-0.1	0.2	0.1	0.5	-0.5	-0.0	0.2	0.3	-0.2	0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.6	0.3	0.5	-0.0	-0.1	0.5	0.5	0.3	1.3	0.2	0.4	0.3	-0.1	0.6	-0.1	-0.4	0.1	-0.1	-0.1	-0.4	1.1	-0.0	-0.0	-0.2	-0.0
Birth weight	0.1	0.1	2.1	-0.3	0.2	-0.1	-0.2	0.2	0.3	0.2	0.4	0.0	0.1	0.0	-0.2	-1.4	-0.2	0.1	0.4	-0.2	0.4	0.2	-0.1	0.1	-0.2	-0.3	-0.2
Arm fat-free mass (right)	0.1	0.5	2.6	0.2	-0.2	1.0	0.5	-0.1	-0.3	0.1	-0.3	-0.0	-0.2	-0.0	0.9	-0.6	0.5	1.6	0.1	0.5	0.9	1.3	0.7	0.8	0.5	1.3	0.7
Number of children fathered	0.1	0.1	0.8	-0.1	0.2	0.2	-0.1	0.3	0.3	0.0	0.1	0.2	0.2	0.1	-0.4	-0.4	-0.1	-0.6	-0.1	-0.1	-0.5	-0.9	-0.2	-0.3	-0.0	-0.4	-0.2
Mean time to correctly identify matches	0.1	0.2	0.6	-0.5	-0.5	-0.0	-0.1	-0.5	-0.4	-0.6	-0.8	-0.4	-0.6	-0.4	0.1	-0.3	-0.1	0.6	0.0	-0.1	0.1	0.2	-0.8	0.4	-0.1	-0.2	-0.1
Arm predicted mass (right)	0.1	0.5	2.6	0.3	-0.1	1.1	0.6	0.1	-0.2	0.3	-0.2	0.1	-0.1	0.1	1.0	-0.6	0.6	1.6	0.2	0.6	1.1	1.4	0.6	0.8	0.6	1.3	0.8
Pulse rate, automated reading	0.1	0.4	2.0	-1.1	-0.8	-0.5	-0.3	-0.8	-0.5	-0.8	-1.4	-0.5	-1.0	-0.6	-0.1	-0.7	-0.4	-0.7	-0.5	-0.4	-0.0	0.1	-1.1	-0.2	-0.6	0.2	-0.4
Alcohol intake frequency.	0.1	0.3	1.9	0.6	-0.1	0.1	0.3	-0.0	-0.3	0.1	-0.2	0.0	-0.2	0.1	0.7	-0.3	0.2	1.2	-0.2	0.2	0.8	0.8	-0.2	0.2	0.4	1.4	0.4
Comparative height size at age 10	0.1	0.7	3.5	-0.4	-0.9	-0.4	-0.6	-0.8	-0.9	-0.6	-0.8	-0.8	-0.9	-0.8	-0.3	-0.9	-0.5	1.9	-1.3	-0.5	0.1	-0.4	-0.3	-1.3	-0.5	1.5	-0.5
Family relationship satisfaction	0.1	0.2	2.3	0.1	-0.1	0.0	-0.3	-0.2	0.1	-0.1	-0.1	-0.2	-0.2	-0.2	-0.1	-1.5	-0.2	0.2	-0.2	-0.2	-0.6	0.0	0.1	-0.7	-0.3	0.3	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.7	0.3	0.0	-0.0	0.4	0.1	0.2	-0.0	-0.2	0.2	-0.1	0.2	0.8	-0.4	0.4	0.4	-0.1	0.4	0.3	0.5	0.2	0.1	0.3	0.8	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	1.4	0.6	-0.1	0.6	0.4	-0.0	-0.2	0.1	-0.1	0.0	-0.1	-0.0	0.5	0.2	0.4	1.2	0.0	0.4	0.4	0.6	0.8	-0.0	0.5	1.2	0.5
Mood swings	0.1	0.2	1.5	0.5	-0.1	0.6	0.5	0.1	0.0	-0.1	-0.3	0.0	-0.2	0.2	0.8	1.2	0.5	0.5	0.6	0.4	0.5	0.5	-0.5	0.7	0.5	0.2	0.6
Long-standing illness, disability or infirmity	0.1	0.1	0.7	0.3	-0.1	-0.3	-0.0	-0.1	0.0	-0.1	0.0	-0.1	-0.2	0.1	0.4	-0.6	-0.0	-0.0	-0.1	-0.0	-0.7	0.5	0.8	-0.2	-0.0	0.1	-0.0
Osteoarthritis (self-reported)	0.1	0.1	1.0	0.4	-0.1	0.1	0.1	-0.1	0.0	-0.0	-0.2	-0.1	-0.0	-0.1	0.4	0.4	0.1	0.3	-0.2	0.1	1.0	0.2	-0.6	0.3	0.0	0.8	0.1
Guilty feelings	0.1	0.1	1.0	0.5	0.4	0.5	0.3	0.4	0.3	0.3	0.3	0.3	0.3	0.3	0.2	1.0	0.3	0.2	0.3	0.3	0.1	0.1	-0.2	0.2	0.2	-0.4	0.3
Commuting to job workplace: Public transport	0.1	0.1	1.7	-0.0	0.0	-0.2	0.0	-0.1	0.2	-0.1	-0.1	-0.0	-0.1	0.1	-0.0	1.3	-0.0	0.1	0.1	-0.0	0.5	-0.2	-1.0	0.1	0.0	-0.3	0.0
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.9	0.7	0.4	0.4	0.3	0.3	0.7	0.4	-0.0	0.4	0.3	0.3	0.3	-0.9	0.2	-0.0	0.3	0.2	-0.1	-0.4	-0.0	-0.3	0.1	-0.1	0.2
Heart attack/myocardial infarction (self-reported)	0.1	0.2	1.3	0.3	-0.3	0.2	0.2	-0.3	-0.1	-0.2	-0.7	-0.1	-0.2	-0.1	0.5	0.3	0.2	1.1	0.0	0.2	0.2	0.6	0.8	0.5	0.1	0.5	0.2
Blood Eosinophil Count	0.0	0.3	3.8	0.1	0.4	0.3	0.0	0.4	0.5	0.4	0.5	0.3	0.2	0.2	-0.1	1.4	0.1	-2.0	0.3	0.1	-0.4	0.3	0.5	-0.1	0.1	-0.3	0.0
Hypothyroidism (self reported)	0.0	0.1	0.4	-0.3	-0.1	-0.4	-0.4	-0.2	-0.1	-0.2	0.3	-0.3	-0.2	-0.2	-0.3	-0.1	-0.4	0.5	-0.4	-0.4	-0.3	-0.1	0.6	-0.4	-0.4	-0.1	-0.3
Tanning	0.0	0.3	1.0	-0.7	-0.3	-1.0	-0.6	-0.4	-0.2	-0.4	-0.4	-0.3	-0.3	-0.5	-1.0	-0.6	-0.6	0.8	-0.4	-0.6	-0.4	-0.5	0.1	-0.2	-0.6	-0.5	-0.7
Qualifications: None of the above	0.0	0.1	0.3	0.3	0.0	0.0	0.2	0.1	0.1	0.1	-0.4	0.1	-0.2	0.2	0.4	-0.6	0.2	-0.4	0.1	0.2	-0.3	0.0	0.3	0.1	0.1	0.1	0.1

Hub : Genes

TRDMT1

Models

Trait associations