TWAS hub - TRIB1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0710	0.0300	0.0096	-0.002	0.020	-0.001	0.02	-0.002	0.8500	0.0015	0.44	0.0016	0.72
2	TCGA	Brain Lower Grade Glioma	0.0285	0.0149	0.0076	0.015	0.006	0.003	NA	0.007	0.0067	0.0620	0.12	NA	0.05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Triglycerides	18.4	30.1	47.5	-3.6	-6.9
LDL Cholesterol	16.3	25.8	43.9	-2.8	-6.6
High cholesterol (Self-reported)	13.7	24.3	40.4	-2.9	-6.4
Medication: Atorvastatin	12.4	15.4	19.2	-3.4	-4.4
Birth weight	7.0	15.1	27.5	1.6	5.2
Comparative height size at age 10	7.0	38.7	70.6	2.6	8.4
Forced expiratory volume in 1-second (FEV1), predicted	6.7	14.0	22.9	2.2	4.8
Medication: Cholesterol lowering	6.5	10.1	12.8	-2.7	-3.6
Cholesterol lowering medication	6.5	9.5	18.4	-0.8	-4.3
Leg fat-free mass (left)	5.4	28.7	54.3	1.8	7.4
Leg fat-free mass (right)	5.4	28.7	54.3	1.8	7.4
Leg predicted mass (left)	5.3	28.0	52.8	1.8	7.3
Leg predicted mass (right)	5.2	27.9	52.9	1.7	7.3
Pulse wave peak to peak time	5.1	6.0	8.0	-2.0	2.8
Risk taking	5.1	7.5	11.5	3.4	1.9
Supplements: Calcium	4.8	5.3	5.4	2.3	2.3
Height	4.4	84.9	132.2	6.1	11.5
Whole body fat-free mass	4.4	24.9	47.3	1.6	6.9
Whole body water mass	4.3	24.7	46.8	1.6	6.8
Lung FEV1/FVC ratio	4.2	21.5	27.8	-5.3	-3.9
Pain all over the body in last month	4.2	4.5	7.4	1.3	-2.7
Basal metabolic rate	4.2	23.4	44.8	1.5	6.7
Crohns Disease (2017)	4.1	8.9	10.6	-3.3	-2.7
Sitting height	4.1	29.4	56.2	1.6	7.5
Pulse wave Arterial Stiffness index	4.0	4.7	4.8	2.1	-2.2
Alcohol drinker status: Never	4.0	4.8	7.2	-1.5	-2.7
Number of full sisters	3.8	4.6	9.2	0.2	-3.0
Pain experienced in last month	3.8	6.3	12.4	0.6	3.5
Trunk fat-free mass	3.7	21.4	40.6	1.5	6.4
Trunk predicted mass	3.6	20.5	39.1	1.4	6.3
Standing height	3.5	34.4	63.8	2.2	8.0
Pack years adult smoking proportion	3.4	5.1	8.0	-2.8	-1.5
Weight	3.4	16.6	31.9	1.1	5.6
Ever had stillbirth, spontaneous miscarriage or termination	3.3	3.5	3.8	1.8	1.9
Pack years of smoking	3.2	4.7	6.9	-2.6	-1.6
HDL Cholesterol	3.1	5.1	8.5	1.3	2.9
Arm predicted mass (left)	3.0	15.4	29.6	1.1	5.4
Medication: Co-codamol	2.9	3.4	6.2	2.5	0.8
Length of working week for main job	2.9	3.2	5.3	-2.3	-1.0
Ulcerative Colitis (UC)	2.8	5.2	10.2	-3.2	0.5
Irritable Bowel Disease (IBD)	2.7	6.3	11.9	-3.5	-0.9
Ovarian Cancer	2.7	3.6	5.9	2.4	1.1
Relative age voice broke	2.7	4.1	4.3	2.0	2.1
Arm fat-free mass (left)	2.7	13.6	26.1	1.0	5.1
Exposure to tobacco smoke outside home	2.6	3.5	3.6	1.9	-1.9
Smoking status: Previous	2.6	3.9	6.2	2.5	-1.2
Ulcerative Colitis	2.5	3.6	4.3	-1.7	2.1
Arm fat-free mass (right)	2.4	12.1	22.8	1.2	4.8
Age at first live birth	2.4	4.3	6.6	-1.4	2.6
Age at First Birth	2.3	3.4	6.2	-2.5	0.7
Waist Hip Ratio (WHR)	2.3	10.5	20.4	0.7	-4.5
Impedance of leg (left)	2.3	11.3	20.2	-1.5	-4.5
Hip circumference	2.3	10.1	18.3	1.3	4.3
Commuting to job workplace: Public transport	2.3	2.7	4.7	0.8	2.2
Arm predicted mass (right)	2.2	11.1	21.3	0.9	4.6
Forced vital capacity (FVC)	2.1	8.2	16.0	0.6	4.0
Qualifications: O levels/GCSEs or equivalent	2.1	3.3	5.6	1.0	2.4
Age at last live birth	2.1	3.0	5.5	0.7	2.3
Cardiovascular Disease	2.0	6.5	12.0	-1.0	-3.5
Impedance of leg (right)	2.0	9.7	17.3	-1.4	-4.2
Stomach or abdominal pain in last month	2.0	2.5	4.2	-2.1	-0.9
Medication: Simvastatin	2.0	2.9	5.2	-0.7	-2.3
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	4.0	2.0	-0.8
Medication for cholesterol, blood pressure or diabetes	2.0	3.2	3.3	1.8	1.8
Long-standing illness, disability or infirmity	2.0	3.0	5.9	2.4	0.2
Type 2 Diabetes (T2D) (2012)	1.9	2.1	3.5	1.9	0.9
Arm fat mass (right)	1.9	8.0	15.5	0.7	3.9
Schizophrenia (2018)	1.8	3.8	4.9	-2.2	-1.6
Coronary Artery Disease (CAD)	1.8	2.2	3.0	-1.2	-1.7
Ever had hysterectomy (womb removed)	1.8	2.0	3.6	0.6	-1.9
Diverticular disease/diverticulitis (self-reported)	1.8	2.1	2.5	-1.3	-1.6
Trunk fat mass	1.8	7.6	14.6	0.7	3.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	3.9	2.0	0.9
Heart disease (mother)	1.8	2.2	3.3	-1.0	-1.8
Blood Eosinophil Count	1.7	12.8	18.5	4.3	2.7
Age when periods started (menarche)	1.7	4.1	8.1	-0.3	-2.8
Number of full brothers	1.7	2.1	4.2	0.1	2.0
Knee pain experienced in last month	1.7	2.7	3.9	1.2	-2.0
Bipolar Disorder or Schizophrenia	1.6	3.9	4.0	-2.0	-2.0
Medication for cholesterol	1.6	2.5	5.0	0.1	2.2
Wears glasses or contact lenses	1.6	1.8	3.0	-1.7	-0.8
Schizophrenia (2014)	1.5	3.2	4.2	-2.1	-1.5
Relative age of first facial hair	1.5	3.1	3.4	1.7	1.8
Chronic bronchitis/emphysema (father)	1.5	1.8	2.3	1.5	1.1
Past tobacco smoking	1.5	2.7	5.0	-2.2	0.7
Mouth/teeth dental problems: Bleeding gums	1.5	2.0	3.2	-1.8	0.9
Whole body fat mass	1.5	6.1	12.1	0.3	3.5
Arm fat mass (left)	1.5	6.2	12.1	0.6	3.5
Medication: Bendroflumethiazide	1.5	2.3	4.5	0.4	2.1
Crohns Disease (2012)	1.4	2.2	4.2	-2.1	-0.4
Hypothyroidism (self reported)	1.4	3.2	5.9	2.4	-0.8
Eye problems/disorders: Glaucoma	1.4	1.6	2.9	0.6	-1.7
Medication for hormone replacement therapy	1.3	1.4	2.8	-0.1	-1.7
Average weekly fortified wine intake	1.3	1.5	2.9	-1.7	0.4
Maternal smoking around birth	1.3	1.9	3.7	-0.2	-1.9
Illnesses of mother	1.3	1.7	3.3	-0.0	1.8
Tense / ‘highly strung’	1.3	2.2	2.3	1.5	-1.4
Hypothyroidism/myxoedema (self-reported)	1.3	2.6	3.3	1.4	-1.8
Leg pain on walking	1.3	1.7	2.0	1.1	-1.4
Average weekly beer plus cider intake	1.3	1.9	2.1	-1.4	1.3
Myopia	1.3	1.8	2.0	1.4	1.3
Hand grip strength (right)	1.2	3.3	6.4	0.4	2.5
Medication: Levothyroxine sodium	1.2	2.0	2.3	1.5	-1.3
Ever unenthusiastic/disinterested for a whole week	1.2	1.4	2.0	0.9	1.4
Qualifications: None of the above	1.2	2.6	5.0	-0.5	-2.2
Illnesses of siblings	1.2	1.6	1.8	-1.2	1.4
Shortness of breath walking on level ground	1.2	1.4	2.8	1.7	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	2.2	0.9	1.5
Miserableness	1.2	2.0	2.9	1.7	1.1
Mother’s age at death	1.2	1.5	1.9	-1.1	1.4
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	1.8	-1.3	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	2.5	-1.5	1.6
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	2.0	0.7	1.4
Hair/balding pattern: Pattern 3	1.1	1.7	2.0	-1.2	-1.4
Number of live births	1.1	1.5	2.6	1.6	-0.7
Mouth/teeth dental problems: Dentures	1.1	1.8	3.0	0.8	1.7
Peak expiratory flow (PEF)	1.1	2.6	4.1	-2.0	1.1
Forced vital capacity (FVC), Best measure	1.1	4.1	8.0	0.6	2.8
Health satisfaction	1.1	1.5	2.8	1.7	-0.3
Alcohol intake frequency.	1.1	2.6	3.1	-1.8	-1.4
Friendships satisfaction	1.1	1.4	2.1	1.5	0.7
Fractured/broken bones in last 5 years	1.1	1.4	2.4	1.6	0.7
Unable to work because of sickness or disability	1.1	1.4	2.8	0.2	1.7
Smoking Status	1.0	2.4	3.4	1.8	-1.2
Hand grip strength (left)	1.0	2.6	5.1	0.1	2.3
Severe depression (siblings)	1.0	1.1	1.4	1.2	-0.9
Townsend deprivation index at recruitment	1.0	1.4	2.9	1.7	0.1
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	2.3	-1.5	1.4
Arm fat percentage (right)	1.0	4.0	7.8	0.4	2.8
Forced expiratory volume in 1-second (FEV1)	1.0	3.4	6.1	-0.9	2.5
Lung cancer (father)	1.0	1.2	1.2	1.1	1.1
High blood pressure (siblings)	1.0	1.5	2.6	0.6	-1.6
Had major operations	1.0	1.2	2.2	1.5	-0.2
Qualifications: nursing, teaching	1.0	1.6	2.3	1.0	1.5
Number of self-reported non-cancer illnesses	1.0	1.7	3.3	0.4	-1.8
Ever smoked	1.0	1.8	3.3	1.8	-0.5
Number of operations (self-reported)	1.0	1.6	1.6	1.2	-1.3
Allergy or Eczema	0.9	2.4	4.9	0.0	-2.2
Ever used hormone-replacement therapy (HRT)	0.9	1.2	2.4	1.6	0.1
Taking other prescription medications	0.9	1.5	2.8	1.7	0.3
Alcohol usually taken with meals	0.9	1.4	2.8	-1.7	0.2
Gout (self-reported)	0.9	1.3	2.6	-0.1	-1.6
Medication: Allopurinol	0.9	1.1	1.5	1.2	-0.9
Leg fat mass (right)	0.9	3.6	6.9	0.5	2.6
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	1.6	-1.3	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	1.2	1.1	1.0
Leg fat mass (left)	0.9	3.4	6.7	0.4	2.6
Schizophrenia vs Biploar Disorder	0.8	1.1	1.8	-1.4	-0.6
HbA1C	0.8	0.9	1.0	0.9	1.0
Primary Biliary Cirrhosis	0.8	1.1	2.0	-1.4	-0.5
Trunk fat percentage	0.8	3.0	6.0	0.3	2.4
Hair/balding pattern: Pattern 2	0.8	1.0	1.5	1.2	0.7
Heart attack	0.8	1.1	1.9	0.4	-1.4
Qualifications: A levels/AS levels or equivalent	0.8	1.7	2.0	1.2	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.0	1.4	0.6
Medication: Paracetamol	0.8	1.4	2.4	1.5	-0.6
Eye problems/disorders: None of the above	0.8	0.9	1.9	0.1	1.4
Medication: Aspirin	0.8	1.0	2.0	-0.2	-1.4
Ever had bowel cancer screening	0.8	0.9	0.9	-0.9	1.0
Illnesses of father: High blood pressure	0.8	1.0	1.7	-1.3	-0.5
Type 2 Diabetes (T2D) (2018)	0.7	1.3	1.7	0.9	1.3
Fluid intelligence score	0.7	1.5	1.6	-1.2	1.3
Pulse rate	0.7	1.1	2.1	0.3	-1.5
Medication: Lansoprazole	0.7	0.8	0.8	0.8	0.9
Hair/balding pattern: Pattern 4	0.7	1.8	3.0	-0.7	1.7
Neck or shoulder pain in last month	0.7	1.0	1.5	1.2	-0.7
Medication: Omeprazole	0.7	0.8	1.4	-1.2	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.6	-1.3	-0.1
Pulse rate, automated reading	0.7	2.4	2.6	-1.6	-1.5
Impedance of whole body	0.7	3.4	6.2	-0.8	-2.5
Intelligence (Savage-Jansen 2018)	0.6	1.9	3.1	0.8	1.8
Alzheimer’s Disease (including proxy)	0.6	0.9	1.3	0.8	-1.1
Verbal and Numeric Reasoning (VNR)	0.6	1.4	2.5	-0.5	1.6
Bipolar Disorder (2011)	0.6	0.5	1.1	-1.0	0.0
Blood Red Count	0.6	6.0	7.6	2.1	2.8
Sensitivity / hurt feelings	0.6	1.0	1.8	-0.4	-1.3
Vitamin and mineral supplements	0.6	0.8	1.6	-0.1	-1.3
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.3	0.5	-1.5
Body mass index (BMI)	0.6	2.5	4.9	0.2	2.2
Medication: Ramipril	0.6	0.8	1.3	-0.6	-1.1
Father’s age at death	0.6	0.8	1.2	-1.1	0.7
Depression (self-reported)	0.6	0.7	0.8	0.8	0.9
Glaucoma (self-reported)	0.6	0.7	0.9	0.7	-0.9
Emphysema/chronic bronchitis	0.6	0.7	1.4	-1.2	-0.0
Medication for pain relief, constipation, heartburn	0.6	1.0	1.4	-0.8	1.2
Arm fat percentage (left)	0.6	2.4	4.6	0.4	2.1
Commuting to job workplace: Walk	0.6	0.6	1.1	1.0	-0.4
Eye problems/disorders: Cataract	0.6	0.7	1.3	1.1	0.2
Medication: Paracetamol	0.6	0.9	1.3	1.1	-0.7
Heart disease (siblings)	0.6	0.8	1.5	0.3	-1.2
Bipolar Disorder (2018)	0.5	0.7	1.3	-0.4	-1.1
Major Depression (MDD)	0.5	0.6	1.0	-0.5	1.0
Diabetes (mother)	0.5	0.7	1.2	1.1	-0.4
Qualifications: CSEs or equivalent	0.5	0.6	1.0	1.0	0.4
Noisy workplace	0.5	0.7	1.2	-0.4	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	2.8	-0.3	1.7
Medication: Ventolin 100micrograms inhaler	0.5	0.6	0.7	0.8	0.8
Qualifications: College or University degree	0.5	1.7	3.3	-0.3	1.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.1	-1.1	0.4
Migraine (self-reported)	0.5	0.7	1.2	-0.4	1.1
Overall health rating	0.5	1.0	2.0	-0.0	-1.4
Illnesses of father: Heart disease	0.5	0.6	1.1	-1.1	-0.4
Medication: Aspirin	0.5	0.6	1.2	0.0	-1.1
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.0	0.6	-1.0
Alcohol drinker status: Previous	0.5	0.6	1.1	-0.1	1.1
Fasting Glucose	0.4	0.5	1.1	-1.0	-0.1
Blood White Count	0.4	3.1	3.4	1.9	1.7
Heel T-Score	0.4	3.4	6.6	-0.5	2.6
Number of treatments/medications taken	0.4	0.6	1.1	0.4	-1.1
Frequency of depressed mood in last 2 weeks	0.4	0.5	0.9	-0.3	1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.6	0.6	0.7	0.8
Waist circumference	0.4	1.4	1.4	1.2	1.2
Nervous feelings	0.4	0.7	1.0	1.0	-0.6
Mouth/teeth dental problems	0.4	0.6	1.2	0.3	-1.1
Falls in the last year	0.4	0.6	0.8	0.9	0.5
Prospective memory result	0.4	0.5	0.5	0.7	-0.6
Pulse wave reflection index	0.4	0.5	0.8	0.9	0.5
Headache pain in last month	0.4	0.7	1.5	-0.1	-1.2
Medication: Amlodipine	0.4	0.6	0.6	0.8	0.8
Chronic bronchitis/emphysema (mother)	0.4	0.5	0.6	0.8	-0.7
Body fat percentage	0.4	1.4	2.8	0.1	1.7
Wheeze or whistling in the chest in last year	0.4	0.7	0.7	-0.8	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	0.9	0.9	0.2
Suffer from ‘nerves’	0.4	0.6	0.6	0.7	0.8
Supplements: Vitamin C	0.4	0.4	0.7	-0.9	0.4
Diabetes diagnosed by doctor	0.4	0.6	1.2	-1.1	0.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.2	0.1	-1.1
Pain type(s) experienced in last month: Hip pain	0.4	0.5	0.6	-0.8	-0.6
Diastolic blood pressure, automated reading	0.4	1.4	1.8	1.3	1.0
Ever depressed for a whole week	0.4	0.5	0.6	0.8	0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	0.5	-0.7	-0.6
Depression (Nagel 2018)	0.3	0.4	0.4	0.6	0.6
Worry (Nagel 2018)	0.3	0.6	1.2	1.1	0.0
Lupus	0.3	0.4	0.6	0.4	0.8
Chronotype (morning person)	0.3	0.6	1.0	-1.0	0.4
Angina	0.3	0.3	0.7	-0.0	-0.8
Current tobacco smoking	0.3	0.5	0.8	-0.3	-0.9
High blood pressure	0.3	0.7	1.4	1.2	-0.1
Multivitamins +/- minerals	0.3	0.4	0.5	0.7	0.5
Allergy	0.3	0.8	1.3	-1.2	0.5
Diabetes (self-reported)	0.3	0.5	0.9	-0.9	0.2
Loud music exposure frequency	0.3	0.3	0.3	-0.5	-0.6
Medication: Blood pressure	0.3	0.6	1.0	1.0	-0.3
Angina (self-reported)	0.3	0.4	0.7	-0.2	-0.8
Medication: Seretide 50 evohaler	0.3	0.3	0.5	-0.7	-0.4
Loneliness, isolation	0.3	0.4	0.8	0.9	-0.1
Illnesses of father: None of the above (group 1)	0.3	0.4	0.8	0.1	0.9
Average weekly champagne plus white wine intake	0.3	0.4	0.5	0.7	0.5
Financial situation satisfaction	0.3	0.4	0.4	0.6	0.6
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.4	-0.6	-0.5
Supplements: Fish oil (including cod liver oil)	0.3	0.3	0.7	0.2	0.8
Depressed Affect (Nagel 2018)	0.2	0.3	0.6	0.7	-0.3
Alzheimer’s Disease (in mother)	0.2	0.2	0.3	0.6	-0.4
Breast Cancer	0.2	0.5	0.9	0.9	0.1
Prostate Cancer	0.2	0.2	0.2	-0.5	-0.5
Mean Putamen Volume	0.2	0.2	0.3	0.3	0.5
BMI	0.2	1.3	2.0	0.8	1.4
Systolic Blood Pressure	0.2	1.1	1.7	0.7	-1.3
Hair Pigment	0.2	4.3	8.6	2.9	-0.2
Average weekly spirits intake	0.2	0.2	0.3	0.5	0.3
Hearing difficulty/problems: Yes	0.2	0.3	0.5	-0.0	0.7
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.5	-0.0	0.7
Fed-up feelings	0.2	0.4	0.7	0.8	-0.3
Supplements: Glucosamine	0.2	0.3	0.4	0.4	0.6
Number of incorrect matches in round	0.2	0.3	0.5	-0.0	-0.7
Hearing difficulty/problems with background noise	0.2	0.3	0.3	0.6	0.5
Had menopause	0.2	0.3	0.4	0.6	0.4
Had other major operations	0.2	0.2	0.4	-0.6	0.1
Time employed in main current job	0.2	0.2	0.3	-0.3	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.5	0.7	0.3
Asthma	0.2	0.4	0.8	0.2	0.9
Breastfed as a baby	0.2	0.3	0.3	0.4	-0.6
Birth weight of first child	0.2	0.3	0.4	0.5	0.7
Comparative body size at age 10	0.2	0.4	0.7	0.4	0.9
Number of children fathered	0.2	0.2	0.3	0.5	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.5	-0.7	-0.0
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.6	-0.7	0.1
Hypertension (Self-reported)	0.2	0.6	1.2	1.1	0.2
Illnesses of siblings: Diabetes	0.2	0.3	0.5	0.7	-0.2
Average weekly red wine intake	0.2	0.2	0.5	0.7	-0.0
Back pain experienced in last month	0.2	0.3	0.4	0.3	-0.7
Mineral and other dietary supplements	0.2	0.2	0.3	-0.5	-0.5
Breast cancer (self-reported)	0.2	0.2	0.3	0.6	-0.4
Osteoporosis (self-reported)	0.2	0.3	0.4	0.4	0.6
Osteoarthritis (self-reported)	0.2	0.2	0.4	0.7	-0.2
Medication: Lisinopril	0.2	0.3	0.5	0.7	-0.4
Ever had prostate specific antigen (PSA) test	0.2	0.3	0.4	-0.6	-0.4
Age started oral contraceptive pill	0.2	0.3	0.4	-0.6	-0.4
Commuting to job workplace: Cycle	0.2	0.2	0.4	-0.1	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.5	0.8	-0.9	0.5
Basal cell carcinoma (self-reported)	0.2	0.2	0.5	0.7	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.3	-0.4	0.5
Neuroticism (Nagel 2018)	0.1	0.3	0.6	0.8	-0.0
Alzheimer’s Disease (in father)	0.1	0.1	0.2	0.5	-0.2
Body Mass Index (BMI) (2010)	0.1	0.2	0.2	-0.5	0.3
Neuroticism (2016)	0.1	0.2	0.2	0.4	-0.4
Rheumatoid Arthritis	0.1	0.2	0.2	0.4	0.4
Blood Platelet Count	0.1	1.1	1.5	-0.9	-1.2
Respiratory disease	0.1	0.1	0.2	-0.2	0.5
Lung FVC	0.1	0.6	0.7	0.7	-0.8
Neuroticism	0.1	0.2	0.3	0.5	0.0
Systolic blood pressure, automated reading	0.1	0.2	0.3	0.2	-0.6
Supplements: Zinc	0.1	0.1	0.2	-0.2	-0.4
Medication: Metformin	0.1	0.1	0.3	0.1	0.5
Diabetes (father)	0.1	0.2	0.3	-0.0	-0.5
Serious illness, injury or assault to yourself	0.1	0.2	0.3	0.5	0.3
Medication: Atenolol	0.1	0.1	0.1	-0.4	-0.2
Financial difficulties in last 2 years	0.1	0.1	0.1	0.2	0.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.4	0.6	0.0
Impedance of arm (right)	0.1	0.3	0.5	0.2	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.2	0.3	0.5	-0.1
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.1	0.3	-0.2
Blood clot in the leg (DVT)	0.1	0.2	0.2	-0.3	0.5
Worry too long after embarrassment	0.1	0.1	0.1	0.4	0.3
Medication: Ibuprofen	0.1	0.1	0.2	0.4	-0.1
Mean time to correctly identify matches	0.1	0.1	0.3	0.5	-0.1
Chest pain or discomfort	0.1	0.1	0.1	0.3	-0.3
Family relationship satisfaction	0.1	0.1	0.2	0.3	0.5
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.1	0.2	-0.4
Asthma (self-reported)	0.1	0.2	0.4	0.2	0.7
Smoking status: Current	0.1	0.2	0.4	-0.2	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.2	0.5	-0.2
Guilty feelings	0.1	0.1	0.1	0.3	-0.3
Ever taken oral contraceptive pill	0.1	0.2	0.2	0.3	0.5
Hearing aid user	0.1	0.1	0.2	0.2	-0.4
Medication: Blood pressure	0.1	0.2	0.3	0.5	0.4
Irritability	0.1	0.2	0.4	-0.6	-0.1
Reaction Time	0.0	0.0	0.1	0.0	-0.3
Tanning	0.0	0.6	0.7	0.8	0.7
Bilateral oophorectomy (both ovaries removed)	0.0	0.0	0.0	-0.2	-0.1
High blood pressure (mother)	0.0	0.0	0.0	-0.0	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.0	0.1	0.2	0.1
Neuroticism score	0.0	0.1	0.1	0.2	-0.4
Alcohol intake versus 10 years previously	0.0	0.1	0.1	0.3	-0.2
Worrier / anxious feelings	0.0	0.0	0.0	0.0	-0.1
Happiness	0.0	0.1	0.1	-0.1	-0.3
Impedance of arm (left)	0.0	0.1	0.1	0.1	-0.4
Exposure to tobacco smoke at home	0.0	0.0	0.0	-0.1	-0.2
Leg fat percentage (right)	0.0	0.0	0.0	-0.0	-0.0
Mood swings	0.0	0.0	0.0	0.1	-0.2
Medication: Gliclazide	0.0	0.0	0.0	0.2	0.1
Leg fat percentage (left)	0.0	0.0	0.0	-0.2	-0.1

Hub : Genes

TRIB1

Models

Trait associations