TWAS hub - TRIM56

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.0629	0.0323	0.00130	0.009	0.017	0.014	NA	0.014	2.8e-02	0.0042	0.00910	NA	0.00880
2	TCGA	Soft Tissue Sarcoma	0.1050	0.0490	0.00300	0.070	0.007	0.035	NA	0.049	5.7e-05	0.1200	0.00380	NA	0.00073
3	TCGA	Thyroid Carcinoma	0.0970	0.0500	0.00075	0.000	0.032	0.043	NA	0.010	3.4e-01	0.0004	0.00005	NA	0.03500

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Pulse rate, automated reading	7.7	25.0	52.0	7.2	1.6	4.5
Pulse rate	3.6	6.1	13.7	3.7	0.4	2.1
Pain type(s) experienced in last month: Hip pain	3.1	4.0	6.4	1.7	2.5	1.6
Back pain experienced in last month	3.0	4.3	9.6	1.6	0.9	3.1
Smoking status: Current	3.0	4.8	9.9	1.9	1.0	3.1
Falls in the last year	2.9	4.0	10.0	0.3	1.4	3.2
Ovarian Cancer	2.7	3.6	7.5	2.7	0.7	1.7
Ever highly irritable/argumentative for 2 days	2.7	3.2	3.7	1.5	1.9	1.9
Illnesses of mother	2.5	3.1	4.4	2.1	0.8	2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	2.5	3.8	5.0	-2.2	-1.5	-2.1
Medication: Ventolin 100micrograms inhaler	2.4	3.0	5.1	-1.7	-2.3	-1.0
Ever unenthusiastic/disinterested for a whole week	2.3	2.8	7.4	1.0	0.2	2.7
Major Depression (MDD)	2.2	2.7	5.5	-1.4	-2.3	0.8
Alcohol drinker status: Previous	2.1	2.4	5.8	0.5	1.1	2.4
Age at First Birth	2.0	2.9	4.6	-2.1	-0.9	-1.8
Hypothyroidism/myxoedema (self-reported)	2.0	4.0	5.4	-2.3	-2.2	-1.2
Medication: Aspirin	2.0	2.6	3.4	-1.4	-1.9	-1.6
Medication: Lisinopril	2.0	2.5	4.3	-1.0	-1.5	-2.1
Blood Red Count	1.9	18.4	38.1	6.2	1.7	3.8
Severe depression (siblings)	1.9	2.1	4.0	-1.4	-0.6	-2.0
Pain all over the body in last month	1.9	2.0	4.3	1.3	2.1	0.3
Mouth/teeth dental problems: Bleeding gums	1.9	2.5	4.0	-1.4	1.2	-2.0
Current tobacco smoking	1.8	2.9	6.1	1.4	0.8	2.5
Hearing difficulty/problems with background noise	1.8	2.8	4.0	2.0	1.8	-1.1
Mouth/teeth dental problems: Dentures	1.8	3.0	4.8	1.7	2.2	1.1
Lung cancer (father)	1.8	2.1	3.9	-2.0	-1.2	-1.0
Handedness (chirality/laterality): Left-handed	1.8	2.2	3.7	1.9	1.2	1.3
Breast cancer (self-reported)	1.8	2.2	5.7	-2.4	-0.9	-0.1
Neuroticism (2016)	1.7	2.4	4.7	-1.0	-2.2	1.3
Medication: Gliclazide	1.7	2.0	3.6	-1.9	-1.5	-0.5
Exposure to tobacco smoke at home	1.6	1.8	2.7	1.4	0.9	1.6
Migraine (self-reported)	1.6	2.0	3.8	1.9	1.2	0.8
Illnesses of father: Heart disease	1.6	2.3	4.1	0.8	1.4	-2.0
Financial situation satisfaction	1.6	2.0	5.3	-0.8	-2.3	0.3
Illnesses of father: High blood pressure	1.6	2.0	4.2	-1.1	-2.0	0.7
Pain experienced in last month	1.6	2.7	3.5	-1.4	-1.9	-1.6
Coronary Artery Disease (CAD)	1.5	1.8	3.9	2.0	0.7	-1.0
Type 2 Diabetes (T2D) (2018)	1.5	2.7	3.3	-1.8	-1.6	-1.5
Medication: Levothyroxine sodium	1.5	2.5	3.6	-1.9	-1.9	-0.6
Mouth/teeth dental problems	1.5	2.4	6.7	-0.6	-2.6	0.3
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.8	2.9	-1.7	-1.1	-1.0
Medication: Seretide 50 evohaler	1.5	1.7	4.1	-1.0	-2.0	-0.2
Diabetes diagnosed by doctor	1.4	2.3	3.6	-1.9	-1.4	-1.2
Mother’s age at death	1.4	1.8	4.6	-2.1	-0.6	-0.6
Average weekly beer plus cider intake	1.4	2.0	2.9	1.6	0.7	1.7
Rheumatoid Arthritis	1.3	1.8	4.2	-0.2	1.0	2.1
Medication: Lansoprazole	1.3	1.5	2.4	-1.5	-0.4	-1.4
Breastfed as a baby	1.3	1.6	4.5	-0.4	-0.3	-2.1
Number of full sisters	1.3	1.6	2.1	-0.9	-1.3	-1.5
Hearing aid user	1.3	1.5	4.2	0.6	0.1	2.0
Qualifications: CSEs or equivalent	1.2	1.5	2.7	-1.6	-1.4	-0.2
Nervous feelings	1.2	2.2	4.4	1.1	1.0	2.1
Allergy	1.2	2.8	5.3	2.3	1.7	0.2
Diabetes (self-reported)	1.2	1.9	2.1	-1.5	-1.4	-1.2
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	2.5	-1.6	-1.3	-0.7
Commuting to job workplace: Car/motor vehicle	1.2	1.4	3.2	0.4	1.8	-0.9
Smoking status: Previous	1.2	1.8	2.7	-1.6	-0.5	-1.5
Loneliness, isolation	1.2	1.7	2.0	-1.2	-1.4	1.3
Alcohol drinker status: Never	1.2	1.4	2.4	-1.4	-0.2	-1.5
Ever smoked	1.2	2.2	3.7	-1.9	-1.5	-0.7
Fractured/broken bones in last 5 years	1.2	1.5	2.2	1.5	1.4	0.7
Fasting Glucose	1.1	1.3	2.8	-1.7	-0.8	-0.6
BMI	1.1	6.3	9.0	3.0	2.6	1.7
Hair Pigment	1.1	31.5	49.0	-6.0	-7.0	-3.0
Eye problems/disorders: Diabetes related eye disease	1.1	1.2	2.9	-0.8	-1.7	-0.2
Alcohol usually taken with meals	1.1	1.8	3.5	-1.2	-0.8	-1.9
Hip circumference	1.1	4.8	7.5	2.7	1.8	1.9
Pulse wave Arterial Stiffness index	1.1	1.3	2.1	-0.6	-1.2	1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.7	-0.4	1.0	-1.6
Pulse wave peak to peak time	1.1	1.3	2.1	0.5	1.2	-1.5
Health satisfaction	1.1	1.4	2.7	1.2	-0.4	1.6
High cholesterol (Self-reported)	1.1	1.9	4.9	0.8	0.3	-2.2
Irritability	1.1	1.8	4.1	-2.0	-0.4	-1.1
Diastolic blood pressure, automated reading	1.1	3.5	9.9	3.2	0.5	0.4
Ever depressed for a whole week	1.1	1.3	2.4	-0.3	-1.2	1.6
Heel T-Score	1.0	8.3	14.4	-3.8	-0.5	-3.2
Supplements: Zinc	1.0	1.1	2.0	-1.0	-0.5	-1.4
Relative age voice broke	1.0	1.6	3.3	-0.8	-1.8	-0.8
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.6	3.6	0.9	0.5	1.9
Had major operations	1.0	1.1	1.4	-1.2	-0.9	1.0
Family relationship satisfaction	1.0	1.2	2.5	0.9	0.5	1.6
Qualifications: nursing, teaching	1.0	1.6	4.6	-0.2	-2.1	0.4
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	2.4	-1.2	1.0	-1.6
Osteoarthritis (self-reported)	1.0	1.3	2.5	1.6	1.1	0.5
Medication: Aspirin	1.0	1.3	2.4	-0.7	-1.5	-1.0
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.2	-0.7	-1.1	-1.5
Myopia	1.0	1.5	1.9	-1.4	-1.3	-1.1
Primary Biliary Cirrhosis	0.9	1.2	1.8	-0.6	-1.4	-1.2
Systolic Blood Pressure	0.9	4.4	13.0	-0.3	-0.5	-3.6
Hypothyroidism (self reported)	0.9	2.2	2.9	-1.7	-1.7	-0.8
Respiratory disease	0.9	2.1	3.3	-0.4	-1.8	1.7
Systolic blood pressure, automated reading	0.9	2.7	7.8	-0.4	0.2	-2.8
Angina	0.9	1.1	2.1	-1.1	-1.5	-0.3
Hayfever, allergic rhinitis or eczema	0.9	1.9	5.0	-2.2	-0.7	-0.5
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	2.3	0.9	0.0	1.5
Fluid intelligence score	0.9	1.8	2.6	0.9	1.5	1.6
Comparative body size at age 10	0.9	2.4	4.1	1.8	2.0	0.0
Emphysema/chronic bronchitis	0.9	1.0	1.9	0.4	-1.0	1.4
Medication for pain relief, constipation, heartburn	0.9	1.5	2.2	1.5	0.9	1.2
Overall health rating	0.9	1.8	5.3	0.5	-0.0	2.3
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	2.8	-1.6	-1.7	-0.1
Osteoporosis (self-reported)	0.9	1.1	1.7	0.4	-1.2	1.3
Ulcerative Colitis (UC)	0.8	1.5	3.0	-1.2	-1.7	-0.4
Reaction Time	0.8	1.6	3.5	0.7	0.9	1.9
Schizophrenia (2014)	0.8	1.7	4.3	-0.7	0.7	-2.1
Type 2 Diabetes (T2D) (2012)	0.8	1.0	2.4	0.3	1.6	0.7
Medication: Metformin	0.8	1.2	3.0	-0.7	-1.7	0.4
Townsend deprivation index at recruitment	0.8	1.1	2.9	0.1	-0.6	1.7
Serious illness, injury or assault to yourself	0.8	0.9	1.9	-0.3	-1.4	0.9
Hair/balding pattern: Pattern 2	0.8	1.0	1.6	-1.1	0.5	1.3
Birth weight	0.8	1.8	2.4	1.4	-1.1	1.5
Neck or shoulder pain in last month	0.8	1.1	1.7	1.3	0.7	1.1
Chest pain or discomfort	0.8	1.2	2.6	0.5	-0.8	-1.6
Illnesses of siblings: Diabetes	0.8	0.9	1.3	-1.1	-0.8	-0.9
Unable to work because of sickness or disability	0.8	1.0	2.0	0.3	0.9	1.4
Supplements: Calcium	0.8	0.8	1.3	-1.0	-1.1	0.4
Crohns Disease (2012)	0.7	1.1	1.9	1.4	-0.5	1.0
Ever used hormone-replacement therapy (HRT)	0.7	0.8	1.6	-0.1	-0.9	1.3
Ever had hysterectomy (womb removed)	0.7	0.7	1.8	-1.4	-0.6	0.3
Medication: Co-codamol	0.7	0.8	1.3	1.1	0.2	1.0
Diabetes (father)	0.7	0.8	2.2	0.5	-0.1	1.5
Age when periods started (menarche)	0.7	1.6	2.8	-0.8	-1.1	-1.7
Number of incorrect matches in round	0.7	1.2	1.8	1.1	0.8	1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	2.3	-1.5	-1.4	-0.9
Qualifications: None of the above	0.7	1.5	2.7	1.0	1.6	0.8
Time employed in main current job	0.7	0.8	1.7	1.3	0.9	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.1	3.5	-1.9	-1.7	-0.4
Blood clot in the leg (DVT)	0.7	0.9	1.8	-1.4	-0.7	-0.5
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.6	0.1	0.9	1.6
Medication: Amlodipine	0.7	1.0	1.6	1.3	-0.4	1.1
Forced vital capacity (FVC), Best measure	0.7	2.5	3.9	-1.9	-2.0	0.2
Shortness of breath walking on level ground	0.7	0.9	2.3	-0.0	-1.5	0.5
Medication: Allopurinol	0.7	1.0	2.5	0.5	-0.4	1.6
Asthma (self-reported)	0.7	1.4	3.3	-0.6	-1.8	-0.6
Medication: Blood pressure	0.7	1.4	2.1	1.4	1.4	0.3
Alzheimer’s Disease (in mother)	0.6	0.7	0.9	-0.9	-0.9	-0.7
Alzheimer’s Disease (in father)	0.6	0.7	1.1	1.0	0.3	0.9
Prostate Cancer	0.6	0.8	2.5	0.2	-1.6	-0.2
Bipolar Disorder (2011)	0.6	0.6	1.1	-0.8	0.0	-1.0
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.4	-1.1	-1.2	0.2
Medication for hormone replacement therapy	0.6	0.7	1.9	-0.1	0.4	1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	2.3	-1.5	-1.3	-0.6
Illnesses of siblings	0.6	0.8	2.2	-0.4	1.5	-0.5
Hair/balding pattern: Pattern 3	0.6	0.9	2.0	1.4	0.7	-0.5
Number of live births	0.6	0.8	2.1	-0.1	-0.6	-1.5
Asthma	0.6	1.1	2.9	-0.5	-1.7	-0.5
Medication: Cholesterol lowering	0.6	0.9	2.1	-0.3	-0.7	-1.4
Impedance of arm (left)	0.6	2.9	5.8	-1.4	-0.9	-2.4
Tense / ‘highly strung’	0.6	1.0	1.9	-0.6	-0.9	-1.4
Glaucoma (self-reported)	0.6	0.7	1.7	0.5	1.3	0.1
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.7	0.7	1.3	0.1
High blood pressure (siblings)	0.6	0.9	1.3	0.1	-1.1	1.2
Leg fat percentage (right)	0.6	2.2	4.9	2.2	0.7	1.1
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.2	0.4	1.1	-0.8
Angina (self-reported)	0.6	0.8	1.7	-0.9	-1.3	-0.1
Knee pain experienced in last month	0.6	0.9	1.7	0.2	1.3	1.0
Average weekly red wine intake	0.6	0.9	1.0	-0.8	-1.0	-1.0
Ever taken oral contraceptive pill	0.6	0.6	1.4	-0.4	-0.6	1.2
Worry (Nagel 2018)	0.5	1.1	1.6	1.0	0.8	1.3
Breast Cancer	0.5	1.3	2.7	0.5	0.9	1.6
Body Mass Index (BMI) (2010)	0.5	0.7	1.9	0.1	1.4	0.3
LDL Cholesterol	0.5	0.8	1.1	1.0	1.0	0.6
Smoking Status	0.5	1.2	2.7	0.2	-0.9	1.6
Cardiovascular Disease	0.5	1.7	4.1	2.0	0.2	1.0
Sensitivity / hurt feelings	0.5	0.9	1.4	-1.2	-1.0	-0.5
Frequency of depressed mood in last 2 weeks	0.5	0.8	1.9	0.5	-0.4	1.4
Multivitamins +/- minerals	0.5	0.6	1.3	-0.5	-0.6	-1.1
Body mass index (BMI)	0.5	2.3	4.5	2.1	1.3	0.9
Waist circumference	0.5	1.9	4.1	2.0	0.6	1.1
Impedance of arm (right)	0.5	2.1	5.5	-0.9	-0.2	-2.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.4	-1.2	-0.6	-0.1
Depression (self-reported)	0.5	0.6	1.1	-0.8	0.2	-1.0
Pulse wave reflection index	0.5	0.6	1.1	-1.1	-0.5	0.7
Gout (self-reported)	0.5	0.6	1.3	0.7	-0.3	1.2
Medication: Omeprazole	0.5	0.6	1.6	-0.2	1.3	-0.1
Supplements: Vitamin C	0.5	0.6	1.6	0.2	0.5	-1.2
Number of self-reported non-cancer illnesses	0.5	0.9	2.0	-0.3	-0.8	-1.4
Commuting to job workplace: Public transport	0.5	0.5	1.4	0.5	-0.0	1.2
Medication: Atorvastatin	0.5	0.7	1.8	1.3	0.5	0.0
Leg fat percentage (left)	0.5	1.9	4.0	2.0	0.6	1.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.5	-0.0	1.2	0.4
Bipolar Disorder or Schizophrenia	0.4	1.1	2.5	-0.0	0.9	-1.6
Verbal and Numeric Reasoning (VNR)	0.4	0.8	1.3	0.9	1.1	0.6
HDL Cholesterol	0.4	0.7	1.9	-0.3	0.3	-1.4
Triglycerides	0.4	0.6	1.6	0.3	1.3	0.3
Chronotype (morning person)	0.4	0.8	2.5	0.0	-0.1	1.6
Relative age of first facial hair	0.4	0.9	2.5	0.5	-0.0	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.3	0.6	-0.0	1.1
Financial difficulties in last 2 years	0.4	0.5	1.2	0.5	-1.1	0.1
Father’s age at death	0.4	0.6	1.2	1.1	0.6	0.4
Birth weight of first child	0.4	0.7	1.6	0.5	-0.5	1.3
Peak expiratory flow (PEF)	0.4	0.9	2.0	-0.8	-0.2	-1.4
Loud music exposure frequency	0.4	0.5	0.9	-0.5	-0.5	0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.6	-0.6	-1.3	-0.4
Exposure to tobacco smoke outside home	0.4	0.5	1.3	0.4	0.2	1.2
Qualifications: College or University degree	0.4	1.2	1.7	-1.3	-0.5	-1.3
Eye problems/disorders: None of the above	0.4	0.4	1.1	0.4	-0.3	-1.0
Medication: Blood pressure	0.4	0.7	1.7	0.5	-0.1	-1.3
Leg fat mass (right)	0.4	1.5	3.3	1.8	0.5	1.0
Suffer from ‘nerves’	0.4	0.7	2.0	0.2	0.1	1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	0.6	-0.8	0.4	-0.7
Mood swings	0.4	0.7	1.0	-1.0	-0.9	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.1	0.5	1.0	-0.3
Commuting to job workplace: Walk	0.4	0.4	0.8	0.9	-0.6	0.4
Number of operations (self-reported)	0.4	0.5	1.1	-1.0	-0.3	0.6
Age started oral contraceptive pill	0.4	0.5	1.2	0.4	0.2	1.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.1	-1.1	-0.7	-0.4
Bipolar Disorder (2018)	0.3	0.5	1.1	-0.5	0.5	-1.1
Schizophrenia (2018)	0.3	0.7	1.4	0.3	0.7	-1.2
Schizophrenia vs Biploar Disorder	0.3	0.4	0.9	0.2	0.6	-0.9
Crohns Disease (2017)	0.3	0.6	1.7	1.3	-0.4	0.0
Allergy or Eczema	0.3	0.7	2.1	-1.4	-0.3	-0.2
Lung FEV1/FVC ratio	0.3	1.3	2.8	0.9	1.7	-0.6
Lung FVC	0.3	1.4	2.2	-1.5	-1.3	-0.5
Neuroticism	0.3	0.7	1.6	-0.7	0.3	1.3
Average weekly fortified wine intake	0.3	0.4	1.0	-0.4	1.0	-0.1
Maternal smoking around birth	0.3	0.5	0.7	0.8	0.8	-0.1
Fed-up feelings	0.3	0.6	0.7	0.7	0.7	0.8
Taking other prescription medications	0.3	0.4	0.9	0.5	-0.3	1.0
High blood pressure	0.3	0.8	2.1	1.5	0.5	-0.3
Supplements: Glucosamine	0.3	0.4	0.7	0.3	0.8	-0.7
Sitting height	0.3	2.1	5.5	-0.8	-0.0	2.4
High blood pressure (mother)	0.3	0.4	1.0	0.1	0.5	-1.0
Had other major operations	0.3	0.3	0.7	-0.8	-0.4	0.3
Forced vital capacity (FVC)	0.3	1.3	2.1	-1.5	-1.3	-0.1
Medication: Ramipril	0.3	0.4	0.6	0.7	0.4	-0.7
Neuroticism score	0.3	0.6	1.7	-0.3	0.2	1.3
Arm fat percentage (right)	0.3	1.0	2.4	1.5	0.7	-0.5
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	1.2	-1.1	-1.0	-0.7
Arm fat mass (right)	0.3	1.0	2.7	1.6	0.6	0.1
Length of working week for main job	0.3	0.3	0.9	-0.4	-0.9	0.0
Body fat percentage	0.3	1.0	2.6	1.6	0.7	0.1
Number of full brothers	0.3	0.3	0.8	0.4	-0.9	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.9	-1.0	-0.4	-0.4
Wheeze or whistling in the chest in last year	0.3	0.5	1.1	-0.7	-1.0	0.2
Age at first live birth	0.3	0.6	0.8	0.5	0.8	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.7	-0.8	0.4	0.6
Leg pain on walking	0.3	0.4	0.8	-0.4	-0.3	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.6	-0.0	-0.7	0.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.5	0.6	0.7	0.6
Hypertension (Self-reported)	0.3	0.9	2.1	1.5	0.7	-0.2
Long-standing illness, disability or infirmity	0.3	0.4	0.6	-0.7	0.4	-0.7
Friendships satisfaction	0.3	0.3	1.0	-0.0	-0.0	1.0
Eye problems/disorders: Cataract	0.3	0.3	0.5	-0.7	-0.0	0.7
Guilty feelings	0.3	0.4	1.2	-0.4	-0.1	1.1
Wears glasses or contact lenses	0.3	0.3	0.8	0.9	-0.1	0.2
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.9	0.9	0.2	0.3
Arm fat-free mass (left)	0.3	1.4	3.0	0.9	0.6	1.7
Risk taking	0.3	0.4	0.9	-0.4	-0.5	0.9
Leg fat mass (left)	0.3	1.2	2.7	1.6	0.3	1.0
Depressed Affect (Nagel 2018)	0.2	0.4	0.5	-0.7	-0.4	0.7
Depression (Nagel 2018)	0.2	0.3	0.7	-0.0	0.5	0.8
Alzheimer’s Disease (including proxy)	0.2	0.3	0.5	-0.6	-0.7	-0.1
Irritable Bowel Disease (IBD)	0.2	0.5	1.3	0.0	-1.1	-0.5
Mean Putamen Volume	0.2	0.2	0.4	0.4	0.2	0.6
Lupus	0.2	0.3	0.5	0.7	0.4	-0.4
Blood Eosinophil Count	0.2	1.5	1.8	1.0	1.2	-1.4
Height	0.2	3.2	7.6	-2.8	-0.9	1.1
Waist Hip Ratio (WHR)	0.2	0.9	2.6	-0.0	-1.6	-0.2
Number of treatments/medications taken	0.2	0.4	1.3	-0.0	-0.2	-1.1
Hearing difficulty/problems: Yes	0.2	0.4	0.9	0.4	1.0	0.2
Vitamin and mineral supplements	0.2	0.3	0.9	-0.0	1.0	0.3
Trunk fat percentage	0.2	0.6	1.3	1.2	0.6	-0.3
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	0.5	-0.4	0.5
Stomach or abdominal pain in last month	0.2	0.2	0.4	-0.6	0.0	-0.6
Medication: Atenolol	0.2	0.3	0.5	0.7	0.5	0.3
Chronic bronchitis/emphysema (father)	0.2	0.2	0.3	-0.3	0.4	-0.5
Past tobacco smoking	0.2	0.5	1.1	1.0	0.5	0.2
Heart attack	0.2	0.2	0.6	-0.2	-0.1	-0.8
Medication: Simvastatin	0.2	0.3	0.8	0.1	-0.9	-0.2
Weight	0.2	1.2	1.8	1.3	0.7	1.1
Noisy workplace	0.2	0.3	0.6	-0.4	-0.8	-0.0
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.5	0.2	-0.0	-1.2
Standing height	0.2	1.8	3.5	-1.9	-1.3	0.4
Medication: Paracetamol	0.2	0.3	0.5	-0.7	0.3	-0.6
Arm fat-free mass (right)	0.2	0.9	2.7	0.4	-0.2	1.6
Worry too long after embarrassment	0.2	0.3	0.7	0.2	-0.8	0.5
Heart disease (mother)	0.2	0.3	0.6	-0.5	0.1	-0.8
Whole body fat mass	0.2	0.7	1.9	1.4	0.4	0.4
Arm predicted mass (right)	0.2	1.3	3.2	0.8	-0.1	1.8
Arm fat percentage (left)	0.2	0.8	2.2	1.5	0.2	-0.4
Medication for cholesterol	0.2	0.3	0.6	-0.0	-0.5	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	0.6	0.5	0.3	0.8
Illnesses of father: None of the above (group 1)	0.2	0.3	0.6	0.1	0.4	0.8
Arm fat mass (left)	0.2	1.0	2.6	1.6	0.4	0.2
Average weekly champagne plus white wine intake	0.2	0.3	0.7	0.2	-0.8	0.2
Medication: Paracetamol	0.2	0.4	1.0	-0.1	1.0	0.1
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.3	-1.1	0.2	-0.0
Basal cell carcinoma (self-reported)	0.2	0.2	0.4	0.7	0.4	0.3
Impedance of whole body	0.2	0.8	1.6	-0.9	-0.4	-1.2
Arm predicted mass (left)	0.2	1.2	2.4	0.9	0.6	1.6
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.7	0.9	-0.0	0.3
Neuroticism (Nagel 2018)	0.1	0.2	0.3	-0.5	-0.5	0.4
Ulcerative Colitis	0.1	0.2	0.4	-0.6	-0.4	0.1
Blood Platelet Count	0.1	1.4	3.2	1.8	1.0	0.1
Blood White Count	0.1	0.9	2.0	1.4	0.8	0.1
Tanning	0.1	1.4	3.8	0.3	2.0	0.4
Diabetes (mother)	0.1	0.1	0.1	-0.3	-0.3	0.1
Pack years adult smoking proportion	0.1	0.1	0.3	-0.6	0.2	0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	0.1	-0.5	0.4
Trunk fat mass	0.1	0.5	1.2	1.1	0.3	0.2
Had menopause	0.1	0.1	0.1	-0.3	-0.4	-0.1
Trunk fat-free mass	0.1	0.7	2.0	0.2	-0.1	1.4
Alcohol intake versus 10 years previously	0.1	0.1	0.1	-0.3	0.3	0.4
Worrier / anxious feelings	0.1	0.1	0.3	0.1	0.3	0.5
Happiness	0.1	0.2	0.5	0.1	-0.1	0.7
Prospective memory result	0.1	0.1	0.2	-0.4	-0.4	0.1
Trunk predicted mass	0.1	0.7	1.9	0.2	-0.2	1.4
Headache pain in last month	0.1	0.2	0.3	-0.2	0.4	-0.5
Medication: Ibuprofen	0.1	0.1	0.3	-0.5	0.3	-0.1
Alcohol intake frequency.	0.1	0.2	0.3	-0.3	0.5	0.4
Comparative height size at age 10	0.1	0.4	0.9	-1.0	0.5	0.1
Age at last live birth	0.1	0.1	0.3	0.6	0.1	0.2
Whole body fat-free mass	0.1	0.6	1.6	0.2	-0.2	1.3
Leg fat-free mass (right)	0.1	0.4	0.7	0.3	-0.5	0.9
Ever had bowel cancer screening	0.1	0.1	0.2	-0.4	-0.4	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.3	0.6	-0.0	0.1
Whole body water mass	0.1	0.5	1.5	0.2	-0.2	1.2
Leg predicted mass (right)	0.1	0.3	0.5	0.2	-0.6	0.7
Miserableness	0.1	0.1	0.4	0.1	-0.0	0.6
Medication: Bendroflumethiazide	0.1	0.2	0.4	0.4	0.6	-0.0
Basal metabolic rate	0.1	0.6	1.4	0.6	-0.0	1.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.3	0.5	0.3	-0.2
Commuting to job workplace: Cycle	0.1	0.1	0.3	-0.1	-0.3	-0.6
Cholesterol lowering medication	0.1	0.2	0.5	0.3	-0.7	-0.2
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.2	0.2	0.2	-0.5
Heart disease (siblings)	0.1	0.1	0.2	0.3	-0.5	-0.1
Pack years of smoking	0.1	0.1	0.2	-0.3	0.3	0.4
HbA1C	0.0	0.0	0.1	-0.2	-0.0	0.3
Hand grip strength (left)	0.0	0.1	0.1	0.1	0.3	0.3
Average weekly spirits intake	0.0	0.1	0.1	-0.1	-0.2	0.4
Impedance of leg (right)	0.0	0.1	0.1	-0.4	-0.0	-0.2
Leg fat-free mass (left)	0.0	0.3	0.5	0.4	-0.4	0.7
Hand grip strength (right)	0.0	0.1	0.2	-0.3	-0.2	0.4
Impedance of leg (left)	0.0	0.1	0.1	-0.3	-0.1	0.3
Leg predicted mass (left)	0.0	0.2	0.4	0.3	-0.4	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.0	0.0	0.0	0.1	0.1	0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	-0.4	0.3	0.2
Number of children fathered	0.0	0.0	0.1	0.2	0.3	0.1
Mean time to correctly identify matches	0.0	0.1	0.1	0.1	0.4	0.3
Mineral and other dietary supplements	0.0	0.1	0.1	-0.4	0.1	0.2
Eye problems/disorders: Glaucoma	0.0	0.1	0.1	0.2	0.3	0.2

Hub : Genes

TRIM56

Models

Trait associations