Hub : Genes

TRIM68

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.3233	0.1118	5.4e-03	0.065	NA	0.025	NA	0.060	2.3e-03	NA	4.3e-02	NA	3.3e-03
2	GTEx	Artery Tibial	0.1501	0.0409	8.9e-05	0.040	NA	0.098	NA	0.082	4.1e-04	NA	4.5e-08	NA	5.7e-07
3	GTEx	Brain Cerebellar Hemisphere	0.3520	0.1090	1.3e-03	0.241	NA	0.158	NA	0.185	7.1e-07	NA	7.3e-05	NA	1.7e-05
4	GTEx	Brain Cerebellum	0.2780	0.0860	1.5e-03	0.107	NA	0.104	NA	0.152	4.6e-04	NA	5.7e-04	NA	3.0e-05
5	GTEx	Esophagus Muscularis	0.2420	0.0660	4.1e-04	0.096	NA	0.039	NA	0.089	2.0e-06	NA	1.9e-03	NA	4.5e-06
6	GTEx	Skin Sun Exposed Lower leg	0.1500	0.0450	3.5e-04	0.035	NA	0.021	NA	0.036	6.5e-04	NA	6.3e-03	NA	5.9e-04
7	GTEx	Testis	0.2270	0.0640	6.0e-04	0.105	NA	0.107	NA	0.117	2.3e-05	NA	1.8e-05	NA	7.7e-06
8	GTEx	Thyroid	0.2760	0.0630	1.3e-06	0.023	NA	0.063	NA	0.044	6.8e-03	NA	1.4e-05	NA	2.6e-04
9	GTEx	Whole Blood	0.0920	0.0350	1.9e-03	0.022	NA	-0.003	NA	0.008	3.8e-03	NA	8.4e-01	NA	5.0e-02
10	METSIM	Adipose	0.0687	0.0203	1.2e-06	0.056	0.040	0.056	0.045	0.064	8.0e-09	9.6e-07	7.7e-09	2.4e-07	6.2e-10
11	NTR	Blood	0.0333	0.0119	6.6e-04	0.025	0.005	0.021	0.024	0.020	1.2e-08	6.6e-03	1.7e-07	2.0e-08	2.7e-07
12	TCGA	Prostate Adenocarcinoma	0.1547	0.0443	3.1e-15	0.197	0.148	0.174	NA	0.189	2.8e-20	3.0e-15	8.0e-18	NA	2.0e-19
13	TCGA	Thyroid Carcinoma	0.0700	0.0300	2.9e-03	0.003	0.020	0.029	NA	0.003	1.5e-01	4.4e-03	7.6e-04	NA	1.5e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Bipolar Disorder (2018)	0.3	0.5	3.2	0.2	0.5	0.2	0.3	0.2	-0.5	0.6	0.4	-1.1	-0.4	0.0	-1.8	-1.0
Bipolar Disorder or Schizophrenia	0.2	0.5	1.0	-0.7	0.0	0.5	0.7	0.8	-0.5	0.6	-0.6	-1.0	-0.5	0.8	-0.9	0.5
Depressed Affect (Nagel 2018)	1.0	2.1	7.2	-1.9	-0.7	2.7	1.6	-1.8	-0.2	-0.9	-1.1	0.9	0.0	-1.8	-1.3	-1.5
Depression (Nagel 2018)	0.8	1.2	2.8	-1.4	-0.6	1.7	0.3	-1.6	-0.0	-0.9	-1.3	0.5	-0.4	-1.6	-0.9	-0.9
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.9	-0.5	2.2	0.6	-0.3	1.2	1.9	1.7	0.9	1.4	-0.8	1.1	1.4	0.5
Neuroticism (Nagel 2018)	0.9	2.2	7.1	-1.6	-1.0	2.7	1.8	-2.0	-0.3	-1.3	-0.2	1.0	0.0	-1.9	-1.4	-1.2
Schizophrenia (2018)	0.3	0.6	2.2	-1.1	-0.4	0.5	0.7	1.0	-0.2	0.3	-1.2	-0.4	-0.4	1.0	0.3	1.5
Schizophrenia vs Biploar Disorder	2.5	3.3	10.2	-1.2	2.1	-0.1	0.2	2.4	2.5	2.2	0.8	0.8	-0.6	2.4	3.2	1.6
Worry (Nagel 2018)	0.8	1.7	4.9	-0.4	-1.2	2.2	1.0	-1.7	-0.7	-1.2	-0.2	0.7	0.5	-1.6	-2.2	-1.3
Alzheimer’s Disease (in mother)	0.4	0.4	1.7	-0.7	-0.1	0.1	0.5	0.6	-1.1	-0.4	0.5	-1.0	-0.0	0.6	0.2	1.3
Alzheimer’s Disease (in father)	1.0	1.0	3.9	0.3	1.6	-0.3	-1.2	1.3	0.5	1.3	0.1	-2.0	-0.1	1.2	-0.5	-0.3
Alzheimer’s Disease (including proxy)	0.4	0.6	3.0	0.0	0.7	-0.3	-0.1	1.1	-0.3	0.5	0.7	-1.7	0.1	1.0	-0.1	1.0
Crohns Disease (2017)	0.2	0.5	1.3	-1.1	-0.4	0.1	1.0	-0.3	-0.8	-0.0	-0.8	-0.4	-1.1	-0.3	-0.9	-0.1
Irritable Bowel Disease (IBD)	0.4	0.9	5.1	0.1	1.0	2.2	1.7	0.7	0.7	1.0	-0.6	-0.2	-0.1	0.8	-0.3	-0.2
Ulcerative Colitis (UC)	1.6	3.0	9.9	1.0	2.7	3.1	1.3	2.0	2.2	2.3	0.4	-0.2	0.6	2.1	0.6	-0.2
Major Depression (MDD)	0.4	0.4	1.2	-1.0	-0.8	0.5	0.5	-0.7	-0.0	-0.8	-0.7	1.1	0.5	-0.6	-0.2	0.1
Reaction Time	0.7	1.4	4.7	-0.4	-0.4	-2.0	-0.8	-1.7	-0.6	-1.0	-2.2	0.4	0.7	-1.6	0.2	-1.1
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.7	-0.0	1.1	-0.3	0.1	0.8	0.3	0.8	1.3	0.9	-0.7	0.8	-0.1	0.2
Breast Cancer	0.9	2.2	4.9	0.3	1.9	-0.0	0.9	1.8	1.8	2.2	1.8	1.4	-1.0	1.9	1.0	-1.5
Ovarian Cancer	0.4	0.5	1.4	-0.6	0.1	-0.9	-0.6	1.1	0.4	1.1	-0.4	-0.0	0.5	1.2	0.6	0.3
Prostate Cancer	0.8	1.1	5.0	1.3	0.5	1.7	2.2	0.8	0.7	0.2	0.6	-1.0	0.3	0.7	0.7	0.7
Age at First Birth	0.4	0.6	1.5	0.3	1.2	-0.2	-0.8	0.8	1.2	1.1	0.5	0.5	0.4	1.0	0.6	-0.3
Bipolar Disorder (2011)	0.8	0.8	2.6	-0.3	-1.1	1.0	0.8	-0.7	-1.1	-1.0	-0.5	-1.1	-0.1	-0.7	-1.6	0.0
Body Mass Index (BMI) (2010)	0.3	0.4	1.0	0.0	-0.9	-0.0	-0.1	-0.7	-1.0	-0.9	-0.3	-0.7	0.6	-0.7	-0.8	0.3
Coronary Artery Disease (CAD)	0.5	0.6	1.6	1.1	0.4	-1.2	-0.3	-0.4	-1.1	-0.2	0.5	-0.9	-0.0	-0.5	-1.3	0.2
Crohns Disease (2012)	0.3	0.5	2.2	-1.5	0.2	-0.8	1.2	0.3	-0.5	0.5	-0.4	-0.6	-0.0	0.1	-0.8	-0.3
Mean Putamen Volume	0.7	0.8	3.9	-0.1	0.7	2.0	0.9	1.0	0.4	1.0	1.2	-0.9	-0.3	0.7	-0.5	-0.8
Fasting Glucose	0.6	0.8	2.4	1.6	0.1	0.2	0.2	1.2	-0.2	0.4	-1.4	-0.5	1.4	1.0	-0.6	-0.7
HbA1C	0.4	0.4	2.1	-0.1	0.3	-1.0	-1.5	0.6	-0.4	0.6	0.3	0.4	-0.9	0.5	-0.4	-0.1
HDL Cholesterol	0.4	0.7	1.8	-0.5	1.1	0.6	-0.0	1.2	1.0	1.0	0.0	0.5	0.2	1.3	1.1	0.6
LDL Cholesterol	0.7	1.2	2.3	1.4	1.4	1.1	0.6	0.9	1.3	1.5	-1.0	0.4	1.0	0.8	-0.2	-1.4
Lupus	0.5	0.7	4.7	-0.2	-0.4	-0.3	1.2	-0.6	-0.0	-0.7	0.3	-2.2	0.6	-0.5	0.8	0.6
Neuroticism (2016)	1.2	1.7	4.6	-0.0	-2.2	-0.8	-0.5	-2.0	-1.6	-1.6	0.4	1.1	-0.1	-1.9	-1.1	-1.2
Primary Biliary Cirrhosis	0.6	0.9	3.1	-0.5	-0.8	0.1	-0.8	-0.2	-1.5	-0.2	-1.4	-1.2	0.5	-0.2	-1.8	-0.9
Rheumatoid Arthritis	0.5	0.7	2.3	0.1	1.0	0.2	0.1	0.0	1.4	1.3	1.4	0.4	0.0	0.0	-0.1	-1.5
Schizophrenia (2014)	0.4	0.9	3.3	-1.4	0.1	0.8	1.1	1.2	0.3	0.5	-1.2	0.1	-0.3	1.2	0.3	1.8
Triglycerides	0.4	0.6	2.3	0.7	0.1	-0.2	-0.1	1.5	-0.5	0.9	0.4	-1.0	-0.3	1.5	-0.4	0.8
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.7	-0.7	-0.3	-0.4	0.6	0.3	-0.2	0.2	0.4	-0.7	0.1	0.2	-1.3	-0.8
Ulcerative Colitis	1.0	1.4	5.6	0.7	1.4	2.4	1.2	1.1	1.7	1.1	-0.2	-0.2	1.2	1.2	0.3	-0.2
Blood Eosinophil Count	0.6	4.3	9.2	0.2	-2.6	1.6	2.4	-2.7	-2.2	-3.0	-2.3	-0.0	1.2	-2.6	-1.4	-1.8
Blood Platelet Count	0.3	3.0	9.3	0.2	-3.0	0.8	1.4	-2.7	-1.9	-2.8	0.7	0.5	-0.0	-2.7	-0.4	-0.0
Blood Red Count	0.4	4.1	11.2	1.4	-2.0	1.8	2.1	-2.0	-0.7	-2.2	-3.0	-0.1	3.4	-1.9	0.3	-2.5
Blood White Count	0.5	3.4	9.7	-0.6	-2.2	2.2	3.1	-2.7	-1.0	-2.5	-0.8	-0.5	-1.2	-2.5	-0.9	-0.2
Heel T-Score	0.3	2.7	13.3	-0.7	-1.7	0.1	-1.1	-1.4	-2.1	-1.7	-3.6	-1.5	0.3	-1.5	-1.4	-0.9
BMI	0.6	3.3	9.7	0.6	-2.7	0.4	0.7	-2.3	-2.2	-3.1	-1.9	-1.3	1.4	-2.4	-0.7	-1.0
Height	0.6	10.8	27.6	2.4	4.9	-1.1	0.6	5.2	4.3	5.0	1.4	2.0	1.7	5.2	1.6	0.4
Waist Hip Ratio (WHR)	0.2	0.9	2.9	1.7	-0.2	1.5	1.1	0.5	-1.3	0.2	0.7	-1.0	0.5	0.3	-0.9	-0.4
Systolic Blood Pressure	0.0	0.2	1.8	0.5	-0.4	1.4	0.3	-0.1	0.1	-0.4	-0.2	0.1	-0.5	-0.2	0.3	0.1
Smoking Status	0.9	2.0	10.3	-1.9	-0.5	-0.8	-1.2	0.4	-2.1	0.5	1.1	-0.9	-1.3	0.5	-3.2	-1.3
Allergy or Eczema	0.7	1.8	4.7	-0.5	-1.6	0.9	-0.2	-2.1	-1.2	-1.7	-1.0	-1.2	-0.0	-2.2	-1.7	-1.0
Cardiovascular Disease	1.0	3.3	10.8	0.7	-2.7	1.6	0.4	-2.7	-1.4	-3.3	-1.7	-0.9	0.2	-2.8	0.6	-0.7
Hypothyroidism (self reported)	0.4	0.9	3.8	-1.0	-0.5	-0.6	0.3	-1.9	-0.2	-1.2	0.0	-1.0	-0.3	-1.9	-0.3	-0.6
Respiratory disease	0.6	1.4	4.2	-1.3	-2.0	0.3	0.1	-1.4	-1.5	-1.6	-0.1	-0.6	-1.2	-1.3	-1.2	0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.0	0.7	-0.3	0.5	0.2	-0.8	-0.2	-0.7	0.2	-1.0	0.1	-1.0	-0.4	-0.8
Lung FEV1/FVC ratio	0.1	0.4	1.5	0.3	0.8	0.1	-0.0	1.2	0.4	1.1	0.3	-0.1	-0.4	1.1	-0.4	0.4
Lung FVC	0.2	1.1	4.6	0.4	0.7	-1.5	-1.0	0.5	1.0	0.1	-0.8	-1.8	0.2	0.4	2.1	0.8
Neuroticism	1.0	2.5	5.8	-1.4	-1.8	2.0	1.3	-2.4	-1.3	-1.8	0.2	1.2	-0.1	-2.3	-1.6	-1.4
Chronotype (morning person)	1.0	2.3	10.4	-1.9	1.6	-0.4	-0.4	1.5	1.0	1.3	1.0	-0.4	-2.0	1.5	1.2	3.2
Hair Pigment	0.0	1.1	2.8	-1.7	-0.5	-1.4	-1.0	-1.1	-1.1	-0.9	0.4	-0.2	-1.7	-1.2	0.5	0.7
Tanning	0.1	1.0	6.0	1.3	-0.3	0.3	-0.1	0.2	0.6	-0.4	-1.1	-1.2	2.4	0.2	1.1	-0.1
Hand grip strength (left)	0.3	0.7	2.8	0.7	0.2	0.9	-0.1	0.2	1.7	-0.1	-0.5	1.6	1.1	0.2	1.0	-0.5
Number of treatments/medications taken	0.7	1.3	2.9	0.2	-1.5	-1.5	-1.7	-1.1	-1.7	-1.4	0.1	0.9	0.3	-0.9	-1.1	-0.3
Average weekly spirits intake	1.3	1.7	4.6	-1.7	-0.9	-2.0	-2.1	-0.4	-1.8	-0.3	0.6	-0.2	-1.5	-0.2	-1.4	0.9
Sensitivity / hurt feelings	0.8	1.4	4.0	-0.7	-1.0	2.0	1.4	-1.9	-0.2	-1.4	-0.7	-0.5	0.5	-1.8	-0.1	-1.1
Frequency of depressed mood in last 2 weeks	0.9	1.3	4.7	-0.3	-0.6	0.7	0.4	-1.9	-1.2	-0.8	-0.7	0.2	-0.2	-1.9	-1.0	-2.2
Hearing difficulty/problems: Yes	1.3	1.9	4.2	-1.9	-2.1	1.2	0.9	-1.7	-0.5	-1.8	0.6	-0.9	-2.0	-1.8	-0.6	0.1
Relative age of first facial hair	0.8	1.7	6.8	1.4	0.9	0.8	-0.9	1.4	1.5	0.8	-0.9	-0.3	1.9	1.3	2.6	-0.2
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.5	-0.3	-0.6	-0.1	0.2	-1.2	-0.7	-0.9	0.6	-0.8	-0.2	-1.2	0.2	-1.1
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.0	-0.9	-0.7	0.2	-0.3	0.2	-1.0	0.1	-0.1	-0.3	-0.2	0.2	-0.5	0.2
Ever had hysterectomy (womb removed)	0.9	1.0	5.6	-1.4	-0.9	0.4	-0.0	0.9	-1.0	-0.2	0.1	-0.3	-1.2	1.0	-0.6	2.4
Systolic blood pressure, automated reading	0.1	0.2	0.6	-0.1	-0.4	0.2	-0.4	0.3	0.5	-0.3	-0.8	0.1	-0.1	0.3	0.7	0.4
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	7.5	2.7	1.5	-1.0	1.0	-0.3	1.3	1.2	0.8	1.0	1.1	-0.3	-0.5	-2.7
Angina	0.8	1.1	2.7	-1.4	-1.3	0.7	0.8	-0.9	-1.3	-0.4	0.2	-1.3	-0.9	-0.8	-1.6	-0.8
Medication for hormone replacement therapy	1.1	1.3	4.2	0.1	1.6	0.3	0.6	1.8	0.7	2.0	1.4	0.2	-0.1	1.8	-0.3	-0.2
Vitamin and mineral supplements	0.5	0.7	1.2	-0.2	1.1	0.9	0.8	0.9	0.9	1.0	0.9	-1.0	-0.1	0.7	0.5	1.1
Supplements: Zinc	0.3	0.3	1.7	-0.3	0.4	-0.0	0.4	-0.1	-0.5	0.1	0.7	0.4	-1.3	-0.1	0.5	0.8
Medication: Co-codamol	1.8	2.1	7.3	-2.7	-1.0	-0.1	-0.9	-1.9	-0.3	-1.5	0.4	-0.6	-2.6	-1.8	0.0	1.0
Medication: Metformin	0.3	0.4	3.7	0.5	0.3	-0.9	-0.2	-0.0	0.4	-0.1	0.1	-1.9	-0.1	-0.3	0.3	0.5
Diabetes (father)	0.4	0.5	1.1	1.0	-0.6	0.2	0.7	-0.9	-0.6	-1.1	-0.6	0.6	0.6	-0.7	-0.1	-0.5
Diabetes (mother)	1.6	2.0	5.3	0.7	2.0	-0.5	-0.2	2.2	2.2	2.3	0.3	0.2	0.5	2.1	1.1	-0.1
Severe depression (siblings)	0.2	0.3	1.0	-0.5	-0.4	0.5	0.3	-0.2	-0.8	-0.4	-0.2	0.5	-1.0	-0.1	-0.6	0.3
Pack years adult smoking proportion	0.9	1.4	3.4	-1.0	-0.4	1.3	1.2	-0.9	-0.9	-0.1	1.3	-1.4	-1.8	-1.2	-1.8	0.3
Impedance of leg (right)	0.1	0.7	2.9	-0.9	1.4	-0.6	-0.2	0.8	0.8	1.7	-0.0	0.1	-0.3	1.0	-0.2	-0.6
Leg fat-free mass (left)	0.2	1.1	3.7	1.7	-0.9	1.0	1.4	-0.2	-0.3	-1.2	-1.3	0.5	1.9	-0.5	0.4	-0.2
Trunk fat percentage	0.1	0.6	3.7	-1.1	-1.0	0.1	0.3	-0.4	-0.4	-0.8	-1.9	-0.8	-0.2	-0.5	-0.1	-0.0
Hand grip strength (right)	0.2	0.6	4.1	0.3	0.6	0.4	0.4	0.4	1.4	0.3	0.4	2.0	-0.0	0.3	0.7	-0.4
Townsend deprivation index at recruitment	0.4	0.5	1.8	-0.5	-0.7	-1.0	-0.2	-0.2	-1.2	-0.4	1.0	-0.2	-0.6	-0.1	-1.4	0.1
Current tobacco smoking	0.4	0.7	3.1	-0.9	-0.0	0.9	0.9	0.5	-1.1	0.4	-0.3	-0.8	-1.1	0.5	-1.8	-0.3
Average weekly fortified wine intake	0.9	1.1	3.5	-1.3	-0.9	-0.4	-0.3	-1.9	-1.0	-1.1	-1.4	-0.0	0.1	-1.6	-0.3	-1.1
Maternal smoking around birth	0.5	0.7	3.9	1.1	-0.0	2.0	0.6	-0.5	0.5	-0.4	0.4	-1.3	0.9	-0.7	0.0	-0.5
Fed-up feelings	0.4	0.7	3.3	-1.8	-0.7	0.4	0.1	-1.2	-0.3	-0.8	0.5	0.7	-0.2	-1.1	-0.9	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	3.2	0.0	-0.0	1.8	1.1	-1.3	0.7	-0.7	-1.1	1.0	-0.3	-1.4	0.3	-0.9
Relative age voice broke	0.4	0.7	2.7	0.6	1.0	-0.1	0.2	0.0	1.6	0.3	0.3	0.7	0.8	0.2	1.5	-1.0
Taking other prescription medications	0.3	0.5	1.1	-0.3	-0.8	-0.2	-1.0	-0.9	0.1	-0.9	-0.8	0.9	0.2	-0.9	0.7	0.1
Age when periods started (menarche)	0.8	1.9	6.2	0.5	1.8	-0.6	-0.1	1.6	1.4	1.9	2.5	1.5	0.1	1.5	1.6	-0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.9	-0.8	-1.1	-0.2	0.0	0.3	-1.4	-0.2	-0.6	0.4	-0.9	0.3	-1.0	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.4	4.8	0.5	-1.8	0.2	-0.2	-1.1	-1.2	-2.2	-2.0	-0.8	0.7	-1.4	-0.0	-0.3
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	2.7	1.6	0.5	0.5	0.5	-0.3	0.6	0.5	-1.1	1.1	1.0	-0.4	0.6	-0.9
Qualifications: CSEs or equivalent	0.4	0.5	2.3	-0.3	0.4	0.7	0.3	-0.4	0.7	-0.3	1.5	1.4	0.0	-0.5	-0.0	0.7
Serious illness, injury or assault to yourself	0.2	0.2	1.2	0.4	0.0	-0.0	0.2	-0.2	-0.7	0.1	0.5	-1.1	-0.1	-0.3	-0.6	-0.4
High blood pressure	0.1	0.4	1.0	-0.3	-0.7	0.5	-0.6	-0.1	-0.4	-0.7	-0.8	-1.0	-0.7	-0.2	0.5	0.5
Hayfever, allergic rhinitis or eczema	0.7	1.6	3.4	-0.7	-1.7	1.6	0.2	-1.8	-1.1	-1.7	-0.8	-0.9	-0.4	-1.9	-1.4	-0.3
Multivitamins +/- minerals	1.0	1.2	2.5	1.5	-1.4	-0.5	-0.4	-1.1	-1.3	-0.9	-1.4	0.3	1.0	-1.0	-1.0	-1.6
Stomach or abdominal pain in last month	1.2	1.5	7.0	-2.6	-0.3	-0.4	-0.6	-0.2	-0.7	0.0	1.4	-0.2	-2.4	-0.1	-1.5	1.0
Supplements: Glucosamine	0.4	0.6	2.1	1.0	-0.0	0.1	-1.4	-0.2	-0.8	0.0	-1.2	-1.0	0.2	-0.3	-1.0	-0.1
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	3.1	-1.3	1.2	-0.5	0.0	1.2	0.1	1.8	-0.2	-1.2	-1.5	1.2	-0.9	1.3
Medication: Atenolol	0.5	0.6	2.1	-0.4	0.6	-1.3	-1.0	1.2	0.5	1.0	-0.1	-0.1	0.5	1.4	0.2	0.4
Medication: Levothyroxine sodium	0.5	0.8	2.8	0.6	-1.2	-0.8	-0.1	-1.5	-0.9	-1.1	0.2	-0.0	0.6	-1.7	-0.3	-0.9
Sitting height	0.2	1.8	6.2	2.1	1.1	0.3	0.8	1.5	1.2	0.8	-0.4	1.4	2.5	1.5	1.1	0.4
Chronic bronchitis/emphysema (father)	2.4	2.8	11.0	-0.7	1.8	1.4	-0.1	1.4	3.3	1.7	0.7	-0.3	-0.4	1.5	3.3	0.9
High blood pressure (mother)	0.6	0.8	2.2	-0.5	-0.3	0.2	1.5	0.3	-1.3	0.2	1.1	0.4	-1.4	0.3	-1.4	0.5
Body mass index (BMI)	0.4	1.7	4.7	-0.0	-2.0	0.1	-0.0	-1.5	-1.5	-2.2	-2.0	-1.2	1.0	-1.6	-0.2	-0.6
Impedance of leg (left)	0.3	1.4	5.4	-1.3	2.0	-0.7	-0.1	1.1	1.1	2.3	0.7	0.4	-1.1	1.3	-0.3	-0.2
Leg predicted mass (left)	0.2	1.0	3.6	1.7	-0.8	0.9	1.4	-0.1	-0.3	-1.1	-1.2	0.5	1.9	-0.4	0.5	-0.1
Trunk fat mass	0.1	0.6	3.6	-0.4	-1.1	0.3	0.7	-0.5	-0.4	-1.1	-1.9	-0.5	0.4	-0.6	0.0	-0.0
Waist circumference	0.1	0.5	1.7	0.4	-1.1	0.5	0.4	0.2	-1.2	-0.7	-0.9	-1.3	0.5	0.1	-0.1	0.6
Number of incorrect matches in round	1.8	2.9	11.6	-3.4	-0.6	-1.0	-2.4	-1.1	0.8	-1.1	0.6	1.1	-2.0	-0.8	1.1	3.0
Past tobacco smoking	1.2	2.2	8.3	1.5	2.0	0.4	0.9	1.0	2.9	1.1	-1.0	0.1	0.5	0.7	2.7	1.2
Alcohol usually taken with meals	0.9	1.5	5.5	0.6	-2.3	-0.0	-0.1	-1.5	-0.8	-1.9	-1.2	1.0	-0.8	-1.6	0.6	1.0
Nervous feelings	0.5	0.9	3.9	0.1	0.1	2.0	1.3	-0.8	0.7	0.1	-0.4	0.0	0.6	-0.7	-0.1	-2.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.8	-0.7	-0.1	1.4	1.0	-1.7	0.1	-0.6	-0.3	0.4	-0.1	-1.7	0.0	-1.5
Hearing difficulty/problems with background noise	1.4	2.2	6.9	-2.6	-2.3	0.7	-0.1	-1.4	-1.8	-1.8	0.7	0.0	-1.6	-1.3	-1.5	0.2
Hair/balding pattern: Pattern 2	0.1	0.2	0.5	0.5	-0.4	0.4	0.3	-0.2	0.6	-0.2	0.5	0.4	0.0	-0.2	0.5	-0.7
Had menopause	1.1	1.3	4.0	-1.7	-1.1	-0.7	-1.8	0.2	-0.2	-0.6	-0.5	-1.7	-0.8	0.4	0.8	2.0
Had other major operations	1.2	1.5	3.7	1.7	1.3	-1.9	-1.1	0.5	0.6	1.5	-1.0	-1.2	1.6	0.6	-0.4	-1.3
Forced vital capacity (FVC)	0.0	0.2	0.7	0.8	0.4	-0.4	0.2	-0.0	0.8	-0.1	-0.3	0.4	0.2	-0.1	0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.8	-0.4	-1.1	0.5	0.1	-0.3	-0.5	-1.4	-0.5	-1.0	-0.4	-0.5	0.1	0.5
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	2.7	-0.9	0.4	1.6	1.6	0.3	0.3	-0.1	-1.2	-0.8	-0.8	0.4	0.7	0.8
Qualifications: None of the above	0.3	0.7	1.8	-0.5	0.3	-1.2	-0.0	1.3	0.9	1.3	0.3	-0.8	0.0	1.3	0.7	-0.2
Financial difficulties in last 2 years	1.0	1.3	3.2	-1.3	-1.4	0.9	1.4	-1.6	-0.6	-1.8	0.9	-0.2	-1.0	-1.6	0.2	-0.0
Mouth/teeth dental problems	0.3	0.5	1.7	0.9	1.0	-0.7	-0.2	1.3	-0.1	0.9	-0.4	0.1	0.3	1.2	0.2	0.2
Heart attack	0.5	0.7	2.5	0.7	0.7	-0.0	0.3	1.0	-0.2	1.6	-0.1	0.3	1.1	1.3	-0.9	-0.4
Allergy	0.4	0.9	2.0	0.5	1.0	-1.4	-0.7	1.3	0.5	0.8	-0.0	1.3	0.8	1.3	1.1	0.3
Pain all over the body in last month	1.2	1.3	4.3	1.1	1.6	-0.0	0.3	0.7	0.8	1.6	0.1	-2.1	1.2	0.6	-0.5	-1.7
Diabetes (self-reported)	0.4	0.6	3.0	1.7	0.9	-0.1	-0.6	-0.4	0.7	0.1	0.3	-1.4	0.0	-0.6	0.3	-0.1
Hayfever/allergic rhinitis (self-reported)	1.3	1.7	5.7	-2.4	-1.5	-1.3	-1.7	-0.7	-2.0	-0.8	0.3	-0.3	-1.1	-0.7	-1.7	0.1
Medication: Ramipril	0.2	0.3	1.8	0.1	0.0	0.4	0.6	0.1	0.5	0.3	-0.2	-1.3	-0.7	0.1	0.4	-0.0
Medication: Simvastatin	0.7	1.0	2.8	0.0	-1.5	-0.5	0.0	-1.4	-1.0	-1.7	-0.5	0.1	1.2	-1.3	-0.1	-1.0
Fluid intelligence score	1.1	2.2	4.8	-0.2	1.7	-1.2	-1.0	2.1	1.5	1.5	1.0	1.6	-0.9	2.2	1.8	1.6
Illnesses of siblings	0.7	1.0	4.6	0.5	1.2	-0.2	-0.4	0.4	2.1	0.2	-0.5	1.2	0.2	0.5	1.9	0.9
Neuroticism score	0.9	1.9	3.9	-1.9	-1.5	1.7	1.2	-2.0	-1.4	-1.7	0.6	0.3	-0.4	-2.0	-1.1	-0.8
Weight	0.1	0.7	3.0	0.7	-1.0	0.4	0.5	-0.2	-0.6	-1.1	-1.7	-0.3	1.5	-0.4	0.2	-0.1
Impedance of arm (right)	0.2	1.0	5.5	-1.4	0.8	0.3	0.1	0.2	0.6	1.2	1.1	0.7	-2.3	0.3	-1.1	0.5
Arm fat percentage (right)	0.5	1.8	5.4	-1.1	-2.3	-0.1	-0.3	-1.6	-1.7	-2.0	-1.7	-1.0	-0.1	-1.6	-1.1	-0.2
Trunk fat-free mass	0.2	1.4	7.2	2.4	-0.1	0.4	1.1	0.7	0.4	-0.5	-0.9	0.9	2.7	0.5	1.0	0.2
Hip circumference	0.1	0.3	1.7	0.0	-0.7	-0.3	0.2	-0.1	0.1	-0.7	-1.3	0.7	0.8	-0.1	0.6	0.2
Time employed in main current job	1.0	1.1	2.7	-1.2	1.6	-0.4	0.5	1.2	0.1	1.3	1.4	-0.1	-1.4	1.3	0.4	1.0
Alcohol intake versus 10 years previously	0.4	0.7	2.2	-0.8	-0.6	1.2	1.3	0.6	-0.5	-0.8	-0.5	-0.6	0.2	0.5	0.5	1.5
Father’s age at death	1.0	1.4	6.4	-2.5	-1.4	1.4	-0.1	-1.5	-0.2	-1.4	-0.4	0.7	-0.8	-1.3	-0.0	0.4
Worrier / anxious feelings	0.6	1.1	3.8	-0.8	-1.5	-0.1	-0.1	-2.0	-0.7	-1.4	0.1	-0.1	-0.1	-1.8	-1.1	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.1	0.1	-0.2	1.0	0.8	-1.4	-0.6	-0.3	0.1	0.3	-0.6	-1.3	-0.9	-1.4
Falls in the last year	0.4	0.5	1.5	-1.0	-0.8	0.8	-0.4	-0.6	0.4	-0.7	0.4	1.1	-1.2	-0.6	0.2	0.5
Hair/balding pattern: Pattern 3	0.4	0.6	2.9	0.4	-0.4	-0.7	-1.0	0.1	-1.7	-0.1	1.1	-0.3	-0.3	0.2	-1.2	0.6
Number of live births	0.4	0.5	2.9	0.8	0.1	0.4	-0.0	0.4	-0.2	0.6	0.1	1.7	0.4	0.7	-1.0	-1.0
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	1.6	0.8	0.9	-0.5	-0.1	0.5	1.3	0.4	-0.1	0.8	0.2	0.4	0.6	0.0
Pulse rate	0.6	0.9	4.3	0.3	-0.4	2.1	1.9	-1.1	0.1	-0.8	0.6	0.5	0.1	-1.2	0.2	-0.0
Happiness	0.7	0.9	2.0	-1.0	-1.1	0.8	1.4	-0.7	0.8	-1.1	-1.2	-0.4	0.4	-0.7	1.4	0.4
Noisy workplace	0.4	0.5	3.4	-0.1	-0.2	0.3	0.8	0.1	-1.0	0.2	0.8	-1.8	-0.5	-0.0	-1.0	-0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.6	0.0	-0.4	-0.0	0.5	-0.9	-1.1	-1.0	-0.6	1.3	-0.3	-0.9	-0.8	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	1.9	-1.3	0.1	0.2	0.4	-0.9	0.6	-0.4	0.5	-0.3	-0.5	-0.8	-0.4	-1.4
Mouth/teeth dental problems: Dentures	0.6	1.0	3.5	-0.2	1.4	0.5	-0.1	1.3	1.3	1.9	0.4	-0.7	-0.0	1.4	0.5	-0.6
Asthma	0.4	0.8	2.2	-1.1	-1.5	0.2	0.5	-1.1	-1.1	-1.1	0.4	-0.5	-1.3	-1.0	-0.1	0.5
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	6.2	0.5	-0.9	1.3	2.3	-1.6	-0.5	-0.9	0.3	-1.5	0.7	-1.7	-2.1	-2.5
Medication: Cholesterol lowering	0.3	0.5	1.8	-1.2	-0.8	-1.3	-0.7	-0.5	-0.6	-0.7	0.6	-0.6	-0.4	-0.3	0.1	0.5
Depression (self-reported)	0.8	1.0	2.7	-0.9	-1.0	0.3	-0.2	-1.5	-0.6	-1.2	1.1	0.7	-1.7	-1.5	-0.5	0.1
Medication: Lansoprazole	0.2	0.3	2.0	-0.5	-0.0	-0.0	-0.5	-0.1	-0.5	-0.3	-0.2	-1.4	-0.6	-0.2	0.2	-0.1
Prospective memory result	0.7	0.9	2.2	0.9	0.8	1.0	0.4	1.5	1.2	1.4	0.4	0.9	0.2	1.4	0.1	-0.8
Lung cancer (father)	2.6	3.0	10.9	-1.2	1.1	-0.8	-0.1	3.0	0.7	1.8	1.1	-0.6	-0.5	2.9	1.4	3.3
Illnesses of mother	0.7	0.9	2.2	0.6	-0.3	-0.3	-1.4	-1.0	0.3	-1.0	-1.5	-0.6	1.1	-1.1	0.8	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.9	1.1	0.9	-0.3	-0.1	0.3	2.0	0.1	-0.3	0.4	0.8	0.2	1.5	0.1
Pulse wave Arterial Stiffness index	0.5	0.6	3.2	-0.5	-0.7	-0.1	-0.4	-0.5	-0.9	-0.3	-1.5	-1.8	0.4	-0.5	-0.3	0.2
Impedance of arm (left)	0.3	1.2	4.1	-1.4	1.4	-0.1	0.2	0.9	0.8	1.8	0.6	0.9	-2.0	1.0	-1.0	0.2
Arm fat mass (right)	0.3	1.2	3.3	-0.1	-1.8	0.1	0.0	-1.1	-1.1	-1.8	-1.8	-1.0	0.7	-1.2	-0.4	-0.3
Trunk predicted mass	0.3	1.5	7.3	2.5	0.0	0.5	1.2	0.8	0.4	-0.3	-0.8	1.0	2.7	0.6	1.0	0.2
Standing height	0.3	3.2	7.5	1.8	2.2	0.8	1.7	2.7	1.9	2.3	0.6	2.1	1.2	2.6	0.7	0.6
Length of working week for main job	0.7	0.7	3.1	-0.0	-0.4	-1.8	-1.5	0.6	-1.1	0.2	-0.8	-0.9	-0.3	0.4	-0.6	0.5
Exposure to tobacco smoke at home	0.4	0.4	1.2	0.3	-0.6	-0.4	-0.7	-1.1	-0.2	-0.7	0.5	0.7	0.3	-1.0	-0.4	-0.9
Breastfed as a baby	1.1	1.3	3.1	-1.8	-1.4	-0.1	-0.9	-1.2	-1.3	-1.6	0.4	0.0	-1.6	-1.3	0.0	1.1
Tense / ‘highly strung’	0.6	0.9	4.5	-0.4	-0.3	2.1	0.9	-1.3	-0.2	-0.5	-0.3	0.1	-0.1	-1.3	-1.1	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	7.4	-1.1	-2.1	1.4	0.3	-2.6	-1.8	-2.5	-0.9	0.9	-0.1	-2.7	-1.4	-0.6
Hair/balding pattern: Pattern 4	0.1	0.2	0.7	0.2	0.3	-0.4	-0.8	0.2	0.7	0.2	-0.3	0.5	0.6	0.3	0.4	-0.2
Birth weight of first child	0.8	1.4	7.8	2.8	-0.2	0.4	1.5	-0.2	0.9	0.2	-0.5	1.6	1.5	-0.2	0.5	-1.3
Peak expiratory flow (PEF)	0.5	1.1	3.5	0.9	1.1	-0.7	-0.8	0.7	1.3	0.2	-1.1	1.9	1.0	0.8	1.5	0.2
Pulse wave reflection index	0.7	0.8	2.8	-1.3	-0.6	-1.7	-1.0	0.0	-1.3	-0.2	-1.0	-1.0	0.0	0.1	-1.0	0.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.2	-0.7	0.4	1.4	1.1	0.7	-0.2	0.5	-0.4	1.5	-0.8	0.6	-0.4	0.7
Loud music exposure frequency	0.6	0.7	2.1	-1.1	-1.0	-0.3	-0.9	-0.9	-0.2	-0.9	-0.3	1.4	-1.0	-0.8	0.1	0.4
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.3	0.8	1.5	0.7	-0.5	0.9	0.0	0.6	-0.8	1.1	0.9	1.0	0.5	0.9
Mouth/teeth dental problems: Bleeding gums	3.5	4.5	12.5	-0.7	-3.1	0.6	0.7	-3.5	-1.8	-3.3	-1.9	0.0	0.9	-3.5	-1.4	-1.7
Blood clot in the leg (DVT)	1.4	1.8	4.1	1.5	1.9	-0.3	0.8	1.8	0.4	2.0	1.5	-1.4	0.5	1.8	-0.9	-0.0
Medication: Paracetamol	1.4	2.3	7.8	0.0	-2.1	-0.8	0.8	-1.7	-2.8	-1.7	0.8	-0.3	-0.3	-1.5	-2.7	-0.6
Headache pain in last month	0.3	0.4	2.3	-0.1	0.3	0.7	0.8	-0.1	-0.3	-0.2	-0.1	-0.1	-1.4	-0.1	0.2	1.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.2	0.8	0.7	0.7	0.9	1.1	0.3	0.8	-0.7	-0.1	0.9	1.0	0.1	0.2
Glaucoma (self-reported)	1.4	1.7	4.5	0.8	-1.3	-1.3	-1.4	-1.2	-2.1	-1.0	-0.7	0.8	1.1	-1.3	-1.5	-1.7
Gout (self-reported)	1.5	2.0	5.0	-0.9	0.8	-1.0	-1.8	1.6	1.2	1.1	2.2	0.6	-0.9	1.7	1.4	2.2
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.8	-0.3	-0.8	-0.8	-0.2	-1.8	-0.3	-1.2	0.2	-0.9	0.1	-2.0	-0.2	-0.7
Medication: Amlodipine	0.5	0.6	3.2	-0.1	0.2	-1.8	-1.1	0.5	-0.3	0.3	0.7	-1.3	-0.8	0.5	-0.5	0.2
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.7	0.3	-0.1	1.3	0.3	0.2	-0.6	0.4	0.1	0.9	-0.1	0.3	-1.1	-1.1
Birth weight	0.2	0.5	2.4	0.5	0.3	1.1	1.6	-0.1	0.1	-0.5	0.2	0.2	1.0	-0.1	1.0	0.4
Chronic bronchitis/emphysema (mother)	0.3	0.3	2.1	0.5	0.0	0.9	-0.4	-0.3	0.1	-0.2	0.2	0.3	0.6	-0.3	0.0	-1.4
High blood pressure (siblings)	0.2	0.3	1.2	0.0	-0.1	-0.5	-0.1	0.7	-1.1	0.5	0.4	-1.0	-0.4	0.7	-0.7	-0.1
Forced vital capacity (FVC), Best measure	0.2	0.7	3.5	1.7	0.6	0.0	0.0	0.1	1.9	-0.1	-0.5	0.0	1.0	0.0	1.1	-0.4
Body fat percentage	0.2	1.0	3.9	-1.1	-1.4	-0.0	0.2	-0.9	-0.9	-1.2	-2.0	-1.0	0.1	-0.9	-0.4	-0.3
Leg fat percentage (right)	0.5	1.8	6.2	-0.8	-1.9	-0.1	-0.1	-1.4	-1.4	-1.6	-2.5	-1.4	0.8	-1.4	-0.6	-1.0
Arm fat-free mass (right)	0.3	1.4	7.9	2.1	0.1	0.2	0.9	0.9	0.2	-0.2	-1.4	0.4	2.8	0.7	1.3	-0.1
Exposure to tobacco smoke outside home	1.3	1.8	4.8	-0.8	-0.3	-2.2	-1.8	-1.6	-1.1	-0.2	-0.6	-0.6	-0.8	-1.4	-2.0	-1.8
Comparative body size at age 10	0.3	0.8	3.2	-1.8	0.3	0.5	1.5	0.7	-0.1	0.1	0.8	-0.5	-0.3	0.7	0.6	1.4
Number of full brothers	0.7	0.9	3.3	-1.4	-0.4	-1.8	-1.5	0.9	-1.2	0.0	-0.1	-0.1	-0.3	0.7	-1.0	0.6
Worry too long after embarrassment	0.2	0.3	0.8	-0.5	-0.4	-0.9	0.1	-0.6	-0.3	-0.9	-0.2	0.3	0.7	-0.6	0.3	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	2.9	3.7	10.4	-2.3	-2.1	1.6	0.1	-3.1	-1.7	-2.5	-0.4	0.5	-0.6	-3.2	-1.9	-1.6
Wheeze or whistling in the chest in last year	0.4	0.7	2.2	-1.5	-0.0	1.3	0.4	0.2	-0.4	0.6	0.9	-0.1	-1.4	0.3	-1.2	-0.6
Number of children fathered	0.3	0.4	1.9	0.6	0.0	0.4	0.6	0.5	0.1	0.1	0.0	0.8	1.4	0.6	0.7	0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	3.1	0.8	0.9	0.6	0.2	0.7	1.2	1.0	-0.3	1.5	1.8	0.8	0.4	-1.2
Age at first live birth	0.6	1.0	4.1	0.2	0.2	0.1	0.3	0.1	1.5	-0.4	1.9	-0.4	-0.7	0.2	1.6	2.0
Pulse wave peak to peak time	0.5	0.6	3.7	0.5	0.7	0.0	0.3	0.6	0.9	0.4	1.4	1.9	-0.4	0.6	0.2	-0.2
Health satisfaction	0.7	0.9	1.5	1.1	-0.8	1.2	1.2	-1.1	0.3	-1.2	-1.1	0.9	0.6	-1.1	0.1	-0.5
Shortness of breath walking on level ground	0.9	1.1	4.9	-0.4	1.2	0.5	-0.3	1.1	1.3	1.4	2.2	0.4	-0.9	1.2	0.1	-0.2
Qualifications: College or University degree	0.2	0.7	4.1	0.8	0.6	-0.5	0.1	0.5	0.3	0.8	1.1	2.0	-0.7	0.5	-0.6	0.5
Eye problems/disorders: None of the above	0.6	0.7	2.8	-1.7	0.1	0.5	1.0	0.2	0.6	-0.3	0.4	-0.9	-0.5	0.2	1.1	1.3
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.8	-0.5	-0.1	0.5	0.6	0.1	1.2	-0.4	0.3	0.0	-0.3	0.3	1.3	1.2
Emphysema/chronic bronchitis	1.0	1.1	2.5	-1.6	1.2	1.3	-0.3	0.9	1.3	1.5	0.4	-1.2	-0.7	0.9	0.2	0.7
Medication for pain relief, constipation, heartburn	1.5	2.5	12.5	1.2	2.1	0.6	-0.2	1.3	2.7	1.3	-0.6	1.1	0.5	1.2	3.5	0.7
Neck or shoulder pain in last month	0.6	0.9	2.2	1.3	-0.5	-1.2	-1.4	-0.8	-0.8	-0.8	-1.5	-0.3	0.8	-0.9	-0.3	-0.5
Medication: Blood pressure	0.2	0.4	1.2	-0.2	0.5	-1.1	-1.1	-0.2	0.5	0.2	0.9	0.5	-0.9	-0.0	0.3	-0.4
Angina (self-reported)	1.2	1.5	4.3	-1.7	-1.5	0.7	0.9	-1.2	-1.6	-0.5	0.2	-1.0	-1.1	-1.1	-2.1	-0.9
Migraine (self-reported)	0.6	0.7	4.9	1.1	0.6	0.6	0.4	-0.1	0.9	-0.2	0.5	-0.0	1.2	0.1	2.2	0.1
Medication: Ibuprofen	1.6	1.9	5.4	0.6	-0.8	1.4	1.9	-1.6	-0.3	-0.8	0.5	-1.6	1.0	-1.6	-1.9	-2.3
Medication: Allopurinol	1.5	2.0	6.8	-0.4	0.7	-2.0	-2.3	1.5	0.8	1.0	0.9	0.4	-0.3	1.6	1.4	2.6
Medication: Omeprazole	0.6	0.7	1.7	0.3	-1.0	0.4	0.1	-1.1	-0.3	-0.8	-1.0	-1.2	0.0	-1.2	-1.3	-0.8
Medication: Seretide 50 evohaler	0.6	0.7	2.1	-0.6	0.9	-0.8	-0.8	0.4	-0.4	1.4	0.1	1.4	-0.3	0.6	-1.2	-0.7
Mean time to correctly identify matches	0.3	0.6	2.1	-0.6	-0.7	-1.4	-0.9	-1.0	-0.9	-0.8	-1.1	0.0	0.4	-0.8	-0.1	-0.1
Heart disease (mother)	0.3	0.3	0.9	-0.1	0.5	0.7	0.1	0.5	0.6	1.0	0.6	0.5	0.0	0.5	-0.8	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.6	3.1	10.1	-2.4	0.5	0.9	1.5	1.2	0.9	0.4	3.1	0.4	-3.2	1.2	1.7	2.3
Whole body fat mass	0.2	0.8	3.6	-0.3	-1.3	0.1	0.4	-0.7	-0.6	-1.2	-1.9	-0.7	0.9	-0.7	-0.0	-0.3
Leg fat mass (right)	0.2	1.0	3.6	0.1	-1.5	0.1	0.4	-0.8	-0.9	-1.4	-1.9	-0.9	1.2	-0.9	-0.1	-0.5
Arm predicted mass (right)	0.3	1.5	8.7	2.1	0.1	0.2	0.9	0.8	0.5	-0.3	-1.4	0.4	3.0	0.6	1.4	-0.4
Pulse rate, automated reading	0.8	2.6	6.9	0.1	-2.6	0.6	0.9	-1.5	-2.6	-2.3	-0.6	-2.5	-0.5	-1.7	-0.5	1.3
Alcohol intake frequency.	0.7	1.6	3.9	-1.5	-0.9	0.7	1.8	-1.6	-0.9	-1.2	-0.6	-2.0	-1.1	-1.8	-0.2	-0.2
Comparative height size at age 10	0.2	1.0	2.5	1.1	-0.1	1.3	1.5	1.6	-0.3	0.4	-0.7	-0.3	1.2	1.4	-0.0	1.0
Number of full sisters	1.3	1.6	8.2	-0.6	1.3	-1.5	-0.9	0.9	-0.2	1.2	2.9	0.7	-1.9	0.8	-0.5	0.5
Suffer from ‘nerves’	2.2	3.4	7.6	-1.7	-2.3	2.8	1.7	-2.5	-2.0	-2.2	-1.0	-0.2	0.4	-2.4	-1.9	-0.6
Overall health rating	0.4	0.8	2.4	-0.5	-0.1	1.6	1.3	-0.4	-0.1	-0.1	1.2	-0.7	-1.5	-0.5	-0.9	0.5
Chest pain or discomfort	0.5	0.7	3.1	-1.2	-0.5	-0.2	0.3	-0.1	-1.2	0.5	0.8	-0.6	-1.8	0.1	-1.1	0.1
Had major operations	2.4	2.8	6.9	-1.5	1.8	-0.4	0.3	2.4	1.6	1.7	0.5	-0.1	-2.0	2.5	1.5	2.6
Age at last live birth	0.6	0.9	4.3	-0.2	0.1	-0.0	0.1	0.5	0.9	-0.2	1.5	0.6	-0.6	0.7	1.7	2.1
Family relationship satisfaction	1.3	1.6	4.1	-0.2	-1.1	0.7	1.8	-1.8	0.0	-1.6	1.2	2.0	-0.4	-1.7	0.8	-0.7
Leg pain on walking	0.2	0.2	1.2	-0.3	-0.2	-0.1	0.2	-0.3	-0.3	-0.4	1.1	-0.4	-0.4	-0.3	0.7	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.5	5.8	0.1	0.2	2.4	0.1	-0.0	-0.5	-0.0	0.2	-0.2	-0.6	-0.1	-0.4	0.6
Commuting to job workplace: Car/motor vehicle	2.5	2.9	13.9	0.2	0.7	-2.4	-3.7	0.2	1.4	0.7	-1.5	-2.6	1.2	0.1	0.3	-2.0
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.6	1.3	0.7	-0.8	-1.3	0.7	0.5	0.4	-1.6	-0.3	1.0	0.7	0.8	0.9
Medication: Aspirin	1.2	1.6	8.0	-1.3	-1.6	0.0	0.2	-1.2	-1.9	-0.6	0.5	0.0	-0.0	-1.1	-2.8	-1.4
Supplements: Vitamin C	0.5	0.5	1.3	-0.6	-1.1	-0.9	0.3	-0.5	-0.6	-0.7	0.9	0.1	-1.2	-0.5	-0.4	0.9
Knee pain experienced in last month	1.4	2.3	6.2	-0.9	-0.9	-2.2	-2.5	-0.6	0.7	-1.2	0.9	-0.1	-1.9	-0.5	2.0	2.4
Hypertension (Self-reported)	0.1	0.4	1.1	0.2	-0.7	1.1	-0.1	-0.0	0.0	-0.6	-0.8	-1.0	-0.5	-0.1	1.0	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.2	0.2	0.2	-0.2	-0.4	0.7	-0.7	0.1	-0.5	-1.1	0.3	0.6	0.2	0.8
Illnesses of father: Heart disease	0.8	1.1	3.3	1.2	1.2	-0.7	-0.0	0.8	0.4	1.6	1.8	0.2	0.2	1.0	-0.8	-1.4
Illnesses of siblings: Diabetes	1.2	1.4	4.9	-0.8	-2.2	-1.0	-1.1	-1.0	-2.2	-1.7	-0.2	-0.0	-0.5	-1.0	-0.7	0.8
Smoking status: Previous	0.8	1.2	4.0	-0.9	-1.3	-0.8	-1.1	-0.7	-1.9	-0.5	1.4	-0.1	-0.6	-0.5	-2.0	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	4.0	0.4	0.1	0.9	2.0	-0.5	0.6	-0.3	-0.2	1.0	0.2	-0.6	-0.1	0.0
Whole body fat-free mass	0.2	1.2	5.7	2.2	-0.3	0.6	1.2	0.4	0.2	-0.7	-0.9	0.8	2.4	0.2	1.0	0.1
Leg fat-free mass (right)	0.1	0.7	2.7	1.6	-0.4	0.9	1.3	0.1	-0.1	-0.7	-0.8	0.8	1.4	-0.2	0.5	0.1
Arm fat percentage (left)	0.4	1.8	5.1	-1.0	-2.3	-0.1	-0.1	-1.4	-1.6	-2.0	-2.0	-0.9	0.1	-1.5	-1.0	-0.4
Average weekly red wine intake	0.4	0.6	5.4	0.2	0.0	-0.7	0.1	0.5	0.4	0.3	0.6	2.3	-0.2	0.6	0.0	0.3
Handedness (chirality/laterality): Left-handed	0.5	0.5	3.0	0.6	-0.4	0.9	0.7	-0.7	-0.5	-0.4	-1.7	0.7	0.2	-0.7	-0.4	-0.6
Mood swings	0.9	1.6	4.0	-1.3	-0.9	1.5	1.5	-2.0	-0.9	-1.0	0.6	0.0	-0.1	-2.0	-1.3	-1.5
Loneliness, isolation	0.5	0.7	3.8	-0.7	-0.5	0.8	1.3	-0.7	-0.5	-0.7	-0.5	2.0	-0.2	-0.7	0.5	0.1
Long-standing illness, disability or infirmity	2.0	3.0	7.0	-2.2	-0.8	-1.3	-2.6	-2.3	-0.7	-1.2	0.9	-2.0	-2.6	-2.4	-0.2	0.3
Ever had bowel cancer screening	0.6	0.7	3.8	-1.2	-0.2	0.6	0.8	0.2	-0.6	0.2	-0.1	0.1	-1.4	0.2	-0.8	1.9
Diabetes diagnosed by doctor	0.3	0.6	2.6	1.6	0.6	-0.6	-0.9	0.0	0.3	-0.1	-0.0	-1.6	0.5	-0.2	0.1	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.5	1.2	-0.6	-1.0	-0.2	-1.2	-0.2	-0.9	0.9	-0.2	-0.0	-1.0	-0.8	-0.6
Friendships satisfaction	0.3	0.4	2.2	0.2	-0.2	-0.1	0.5	-0.4	-0.1	-0.5	-1.5	0.1	0.7	-0.5	0.2	-1.1
Qualifications: nursing, teaching	0.2	0.3	1.0	0.4	-0.0	0.6	0.2	-0.8	-0.7	-0.3	-0.8	-0.4	0.3	-1.0	0.0	-0.7
Commuting to job workplace: Walk	0.7	0.7	3.1	-0.8	0.0	0.7	1.2	0.8	-0.5	0.2	-0.8	0.6	-0.9	0.9	0.4	1.8
Eye problems/disorders: Cataract	0.5	0.6	3.5	0.7	-0.2	-0.9	-1.9	0.7	-0.9	0.2	0.2	0.9	0.3	0.8	0.1	0.0
Mouth/teeth dental problems: Mouth ulcers	0.5	0.7	2.6	-1.6	-0.5	0.0	-0.1	-0.7	-0.6	-0.4	1.2	-0.9	-0.9	-0.7	-0.9	1.1
Medication for cholesterol	0.2	0.3	1.5	0.4	0.5	0.2	0.3	-0.4	1.2	-0.1	0.4	0.7	0.8	-0.4	0.6	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.4	4.5	-0.6	1.9	-1.8	-2.1	1.8	1.2	2.1	-0.1	0.9	-1.8	1.9	0.9	1.3
Back pain experienced in last month	1.6	2.3	8.9	-3.0	-1.5	-1.4	-1.4	-1.8	-1.3	-1.7	-0.1	-0.7	-1.7	-1.9	-0.6	-0.1
Mineral and other dietary supplements	0.5	0.6	2.6	-0.2	-0.1	0.2	1.6	-0.4	0.9	-0.1	0.6	-0.9	0.0	-0.5	1.5	-0.8
Breast cancer (self-reported)	0.7	0.8	3.2	-0.1	-0.1	-1.8	-1.2	0.8	-0.1	0.2	-1.4	-0.3	0.9	0.8	1.2	0.3
Asthma (self-reported)	0.4	0.8	2.0	-1.3	-1.4	-0.2	0.2	-1.0	-1.2	-1.0	0.4	-0.6	-1.3	-0.8	-0.3	0.4
Osteoporosis (self-reported)	1.4	1.7	4.0	-1.6	-1.4	-0.7	-0.1	-1.5	-1.4	-1.3	0.5	1.7	-2.0	-1.3	-1.0	1.4
Osteoarthritis (self-reported)	1.3	1.7	4.8	-2.2	-2.1	-0.6	-0.5	-1.4	-1.2	-1.9	-0.4	-0.0	-1.7	-1.3	-0.2	0.8
Medication: Aspirin	1.4	1.8	10.3	-1.0	-1.5	-0.3	-0.0	-1.2	-2.1	-0.4	0.1	0.0	0.3	-1.0	-3.2	-1.7
Medication: Gliclazide	1.2	1.4	5.4	0.6	-1.3	1.7	2.3	-1.1	-0.3	-1.6	-0.0	-1.1	0.0	-1.5	0.2	0.3
Illnesses of father: None of the above (group 1)	0.7	0.9	2.7	-1.2	-0.9	-1.6	-0.8	0.2	-1.6	-0.8	-0.7	-0.0	-0.1	0.1	0.4	1.3
Smoking status: Current	0.4	0.6	2.2	-1.0	-0.0	0.8	0.6	0.5	-1.0	0.3	-0.5	-0.9	-0.9	0.5	-1.5	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	2.8	0.2	0.4	-1.1	-0.6	0.9	1.7	0.3	-0.2	0.0	0.9	1.0	1.6	0.5
Whole body water mass	0.2	1.1	5.5	2.1	-0.4	0.6	1.1	0.4	0.1	-0.8	-0.9	0.7	2.4	0.1	0.9	0.1
Leg predicted mass (right)	0.1	0.8	2.8	1.7	-0.5	1.0	1.3	0.0	-0.1	-0.8	-0.8	0.9	1.4	-0.3	0.4	0.1
Arm fat mass (left)	0.3	1.2	3.9	-0.0	-1.8	0.0	0.1	-1.1	-1.1	-1.7	-2.0	-0.9	0.8	-1.2	-0.4	-0.6
Number of self-reported non-cancer illnesses	2.0	3.4	10.3	-0.6	-3.2	0.4	-0.3	-2.3	-2.5	-3.0	-1.3	-2.3	0.4	-2.4	-0.8	-0.3
Average weekly champagne plus white wine intake	0.3	0.4	1.8	-0.3	-0.7	-1.1	-0.0	-0.2	-0.4	-0.2	-0.4	1.2	-0.3	-0.2	0.4	1.3
Miserableness	1.5	2.6	6.4	-2.5	-1.3	1.0	1.4	-2.0	-1.2	-1.0	1.3	-0.1	-2.2	-2.0	-2.1	-0.9
Guilty feelings	1.0	1.5	8.8	0.2	1.7	0.7	0.7	1.2	-0.5	1.6	3.0	0.5	-0.8	1.1	-0.5	0.1
Wears glasses or contact lenses	1.0	1.2	3.8	-0.5	0.3	1.3	-0.9	1.5	0.3	1.2	-0.2	0.8	-0.6	1.6	0.9	1.9
Ever taken oral contraceptive pill	0.7	0.7	3.9	-0.2	-0.2	-0.5	-0.8	-0.6	-0.8	-0.2	-0.0	2.0	-0.1	-0.5	-1.7	-0.8
Hearing aid user	0.6	0.7	2.9	-0.4	0.2	0.8	0.2	0.2	1.4	0.2	-1.7	-0.1	-0.0	0.4	1.7	0.2
Mother’s age at death	0.4	0.5	1.5	0.3	0.5	-0.2	0.4	1.0	0.4	1.2	1.2	0.1	0.1	1.2	0.0	0.0
Financial situation satisfaction	0.7	0.8	3.0	0.7	-0.8	0.5	1.0	-0.2	0.2	-1.1	-1.5	-0.1	0.5	-0.1	1.7	1.4
Tinnitus: Yes, now most or all of the time	0.5	0.6	4.0	-0.8	-0.3	0.4	-0.9	0.7	-0.2	0.0	-0.2	-2.0	-1.1	0.6	-0.2	0.3
Commuting to job workplace: Public transport	1.2	1.5	6.1	-0.4	-0.7	2.5	2.2	-0.8	-1.2	-0.4	1.1	0.6	-1.1	-0.9	-1.3	-0.7
Eye problems/disorders: Glaucoma	0.9	1.0	3.4	0.8	-0.5	-1.5	-0.7	-0.8	-1.8	-0.3	-0.3	0.9	0.3	-0.9	-1.5	-1.3
Medication: Blood pressure	0.3	0.5	1.9	0.4	-1.3	-0.9	-0.5	0.1	-1.3	-0.6	-1.4	-0.7	0.0	0.0	-0.0	0.0
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.3	-0.4	-1.8	-0.5	0.4	-1.5	-0.9	-1.7	1.0	-0.3	-0.6	-1.4	-0.3	-0.1
Supplements: Fish oil (including cod liver oil)	1.1	1.4	5.5	-0.1	0.1	-1.4	-2.3	1.5	-1.2	0.7	-0.3	0.8	0.2	1.7	-1.2	1.4
High cholesterol (Self-reported)	0.7	1.2	2.6	-1.3	-1.4	-0.9	-0.3	-1.6	-0.9	-1.5	0.8	1.3	-0.7	-1.4	-0.2	0.5
Medication: Bendroflumethiazide	0.5	0.8	3.4	-1.8	0.4	-0.1	-0.9	-0.1	0.2	-0.2	-0.4	0.5	-1.7	0.0	0.6	1.3
Medication: Paracetamol	1.9	2.9	9.3	1.2	-2.0	-1.1	0.6	-1.9	-3.0	-1.8	0.6	-0.5	0.6	-1.8	-3.0	-1.3
Medication: Lisinopril	0.8	1.0	3.5	-0.5	-0.5	0.8	0.2	-1.9	-0.6	-1.3	-1.1	0.9	-0.9	-1.8	-0.3	-0.9
Medication: Atorvastatin	1.1	1.3	6.3	-0.3	-0.1	-2.0	-2.5	0.6	0.6	0.6	-0.5	-2.3	0.0	0.7	0.3	0.3
Illnesses of father: High blood pressure	0.7	0.8	3.0	1.7	0.2	0.7	0.5	-0.7	0.8	0.3	0.4	1.4	1.0	-0.5	-0.4	-1.5
Alcohol drinker status: Never	1.0	1.2	3.6	-0.9	0.2	0.4	1.4	0.5	1.9	0.4	1.7	0.4	-1.5	0.4	1.7	0.9
Ever smoked	2.4	4.2	15.8	-1.8	-2.7	0.8	0.5	-1.6	-3.8	-1.9	1.0	0.3	-0.3	-1.6	-4.0	-1.8
Basal metabolic rate	0.2	1.0	4.8	1.8	-0.6	0.5	1.0	0.1	-0.1	-0.9	-1.3	0.5	2.2	-0.1	0.7	-0.1
Leg fat percentage (left)	0.4	1.5	4.2	-1.3	-1.8	-0.1	0.1	-1.4	-1.4	-1.5	-2.0	-1.2	-0.0	-1.4	-0.6	-0.7
Arm fat-free mass (left)	0.2	1.1	6.0	1.8	-0.4	0.5	1.0	0.1	-0.3	-0.7	-1.4	0.3	2.4	-0.0	0.6	-0.5
Number of operations (self-reported)	2.0	3.0	7.7	-1.4	2.1	-0.9	-0.6	2.5	1.3	2.4	0.2	-0.5	-1.9	2.8	1.3	2.1
Average weekly beer plus cider intake	0.6	0.8	4.3	-0.8	-0.1	-0.6	-2.1	-0.1	-0.4	-0.3	1.3	-1.3	0.8	-0.1	-1.2	-0.6
Irritability	1.2	2.0	3.6	-1.4	-1.5	1.9	0.9	-1.8	-1.8	-1.8	-0.2	-0.2	-0.6	-1.9	-1.5	-0.8
Risk taking	0.4	0.6	1.2	0.3	-0.7	0.3	-0.6	-1.0	-0.9	-1.1	-0.2	1.0	0.6	-1.1	-0.6	-1.1
Ever had prostate specific antigen (PSA) test	0.8	0.9	4.6	-2.1	-0.2	0.6	1.2	-0.3	-0.2	-0.5	-0.4	-0.1	-1.3	-0.5	0.9	1.2
Fractured/broken bones in last 5 years	0.3	0.4	1.2	0.9	-0.5	0.0	0.4	-0.2	0.8	-0.2	-1.1	-0.2	-0.1	-0.1	1.1	-0.7
Age started oral contraceptive pill	0.5	0.6	2.0	0.6	-0.1	1.4	0.9	0.8	0.2	-0.1	-0.2	-0.6	0.5	0.8	0.9	1.3
Diastolic blood pressure, automated reading	0.5	1.5	5.6	0.3	-1.9	0.3	-0.2	-1.7	-0.3	-2.4	-1.7	-0.0	0.6	-1.8	0.6	-0.2
Ever depressed for a whole week	1.2	1.5	5.9	-2.4	-1.2	1.0	-0.5	-1.1	-1.1	-1.5	-1.4	-0.3	-1.3	-1.1	-0.4	1.1
Unable to work because of sickness or disability	0.9	1.2	5.0	-1.9	0.1	0.2	0.9	-1.4	-0.6	-0.8	0.3	-0.8	-2.2	-1.4	-0.6	0.4
Commuting to job workplace: Cycle	0.6	0.8	2.7	0.6	-0.3	-0.6	-0.3	-0.4	-1.2	-0.1	0.6	1.6	0.6	-0.3	-1.7	-1.0
Myopia	0.5	0.8	2.4	-1.5	0.1	-1.0	-1.4	0.1	-0.1	0.2	0.4	0.3	-1.5	0.2	0.1	1.6
Vascular/heart problems diagnosed by doctor	0.2	0.4	2.0	0.4	0.9	-0.6	0.1	0.6	0.4	0.7	0.3	1.4	0.5	0.6	-0.6	-0.1
Cholesterol lowering medication	0.9	1.3	4.8	0.6	-2.2	0.4	0.5	-1.3	-1.6	-1.6	-0.8	-0.6	0.7	-1.4	-0.7	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	5.0	0.1	-0.2	-0.8	-0.9	-0.2	-0.1	0.1	-0.9	-2.2	-0.4	-0.4	-0.9	-0.6
Pain experienced in last month	0.3	0.6	2.5	0.5	-0.4	0.2	-0.6	1.6	-0.6	0.5	-0.4	0.5	0.2	1.6	0.3	0.5
Supplements: Calcium	0.5	0.5	1.4	0.7	1.1	1.2	0.3	-0.1	1.0	0.7	-0.6	-0.1	0.8	-0.1	1.0	-0.6
Basal cell carcinoma (self-reported)	0.2	0.3	1.1	-0.4	0.3	0.0	0.4	0.3	0.4	0.3	-0.6	-0.7	-1.1	0.2	0.5	0.9
Heart attack/myocardial infarction (self-reported)	0.5	0.6	2.3	0.6	0.6	-0.3	0.2	0.9	-0.5	1.5	0.2	0.3	0.8	1.2	-1.2	-0.3
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	4.0	1.4	1.9	-0.7	0.5	1.8	0.4	2.0	1.6	-1.2	0.4	1.9	-0.8	0.2
Heart disease (siblings)	0.9	1.1	2.2	0.6	-1.0	0.6	0.5	-1.2	-0.9	-1.0	-1.2	-1.2	1.5	-1.3	-1.0	-1.3
Alcohol drinker status: Previous	2.6	3.0	7.9	-1.1	-1.9	0.7	1.0	-2.7	-2.0	-2.5	-1.7	-1.1	0.0	-2.8	-1.2	-1.0
Pack years of smoking	1.0	1.4	3.6	-1.2	-0.5	1.4	1.1	-1.1	-0.7	-0.2	1.0	-1.7	-1.9	-1.3	-1.5	0.6
Impedance of whole body	0.3	1.3	4.6	-1.4	1.8	-0.5	0.1	0.8	1.0	2.1	0.6	0.4	-1.7	1.0	-0.9	-0.4
Leg fat mass (left)	0.2	0.9	3.1	-0.4	-1.5	0.3	0.5	-0.9	-0.9	-1.3	-1.8	-0.8	0.7	-0.9	-0.2	-0.3
Arm predicted mass (left)	0.2	1.2	7.3	2.1	-0.4	0.1	0.7	0.2	-0.2	-0.8	-1.4	0.3	2.7	0.0	0.7	-0.6