TWAS hub - TRIM72

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0820	0.0310	1.8e-05	0.045	0.038	0.045	0.043	0.040	3.3e-06	1.7e-05	3.4e-06	5.6e-06	1.2e-05
2	ROSMAP	Brain Pre-frontal Cortex	0.0819	0.0257	6.3e-11	0.106	0.091	0.100	0.095	0.102	1.6e-13	1.0e-11	8.0e-13	2.8e-12	5.0e-13

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Smoking status: Previous	9.0	13.5	14.1	-3.6	-3.8
Illnesses of siblings	8.8	12.4	13.2	3.4	3.6
Relative age voice broke	8.0	12.3	12.9	-3.4	-3.6
Tinnitus: Yes, now most or all of the time	7.6	8.8	10.7	-2.6	-3.3
Severe depression (siblings)	7.3	8.2	8.8	2.8	3.0
Lupus	7.1	10.8	18.7	4.3	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.0	14.9	18.9	3.3	4.4
Fractured/broken bones in last 5 years	6.9	8.9	9.9	-2.8	-3.1
Past tobacco smoking	6.7	12.3	12.4	3.5	3.5
Hip circumference	6.7	28.7	35.8	-4.7	-6.0
Prospective memory result	6.6	8.1	8.9	2.7	3.0
High blood pressure (siblings)	6.6	9.6	10.3	-3.0	-3.2
Smoking Status	6.4	15.2	15.7	-3.8	-4.0
Osteoarthritis (self-reported)	6.4	8.3	9.4	3.1	2.7
Alzheimer’s Disease (including proxy)	6.0	8.7	9.4	3.1	2.8
Worrier / anxious feelings	6.0	11.4	11.5	3.4	3.4
Leg fat mass (right)	5.7	22.1	27.7	-4.1	-5.3
Myopia	5.7	8.2	8.7	-2.8	-3.0
Number of incorrect matches in round	5.4	8.9	9.4	2.9	3.1
Comparative body size at age 10	5.3	14.7	16.3	-3.6	-4.0
Body mass index (BMI)	5.2	22.2	27.6	-4.1	-5.3
Leg fat mass (left)	5.2	20.4	25.7	-3.9	-5.1
Leg fat percentage (right)	4.8	17.3	21.6	-3.6	-4.6
Relative age of first facial hair	4.7	9.6	11.6	-2.8	-3.4
Qualifications: CSEs or equivalent	4.7	6.2	6.2	-2.5	-2.5
Worry (Nagel 2018)	4.6	9.6	12.7	2.6	3.6
Pain all over the body in last month	4.6	4.9	5.0	-2.2	-2.2
Leg fat percentage (left)	4.6	16.7	21.0	-3.5	-4.6
Arm fat mass (left)	4.2	17.4	23.2	-3.4	-4.8
Ever smoked	4.2	7.4	7.7	-2.8	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.1	4.8	5.2	2.1	2.3
Wears glasses or contact lenses	4.1	4.7	5.0	-2.1	-2.2
Arm fat mass (right)	4.0	16.4	22.0	-3.3	-4.7
Arm fat percentage (left)	4.0	15.8	21.2	-3.2	-4.6
Whole body fat mass	3.9	16.1	21.5	-3.3	-4.6
Eye problems/disorders: Glaucoma	3.9	4.7	5.0	2.2	2.1
Fasting Glucose	3.8	4.5	5.0	-2.2	-2.0
Lung FVC	3.8	19.3	21.5	4.1	4.6
Waist circumference	3.8	13.9	18.6	-3.0	-4.3
Forced vital capacity (FVC)	3.8	14.6	15.3	3.7	3.9
Weight	3.8	18.8	24.5	-3.6	-5.0
Arm fat percentage (right)	3.8	15.2	20.2	-3.2	-4.5
Body fat percentage	3.7	14.6	19.7	-3.1	-4.4
Blood Red Count	3.6	35.1	38.3	5.6	6.2
Mouth/teeth dental problems: Mouth ulcers	3.6	5.7	6.5	-2.6	-2.2
Multivitamins +/- minerals	3.5	4.5	4.6	-2.1	-2.1
Hand grip strength (left)	3.4	8.9	9.1	-3.0	-3.0
Mouth/teeth dental problems: Bleeding gums	3.4	4.4	4.8	-2.2	-2.0
Birth weight	3.4	7.3	8.0	-2.6	-2.8
Hearing difficulty/problems: Yes	3.3	5.0	5.1	-2.3	-2.2
Medication: Ramipril	3.3	4.2	5.7	-1.6	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.3	3.8	5.5	1.5	2.3
BMI	3.2	18.5	22.9	-3.7	-4.8
Trunk fat mass	3.2	13.9	19.1	-3.0	-4.4
Medication: Simvastatin	3.2	4.6	5.0	-2.1	-2.2
Glaucoma (self-reported)	3.2	3.7	3.9	2.0	1.9
Hand grip strength (right)	3.1	8.5	8.5	-2.9	-2.9
Number of full brothers	3.1	3.9	5.2	-1.6	-2.3
Vascular/heart problems diagnosed by doctor	3.1	8.5	11.8	2.3	3.4
Cardiovascular Disease	3.0	10.0	11.5	-2.9	-3.4
Number of live births	3.0	4.3	4.6	-2.0	-2.2
Waist Hip Ratio (WHR)	2.9	13.1	13.5	3.6	3.7
Forced vital capacity (FVC), Best measure	2.9	10.5	11.1	3.1	3.3
Illnesses of siblings: Diabetes	2.9	3.6	4.4	-1.7	-2.1
Illnesses of father: None of the above (group 1)	2.9	3.6	3.9	2.0	1.8
Trunk fat percentage	2.8	11.2	15.5	-2.6	-3.9
Chronic bronchitis/emphysema (father)	2.8	3.3	3.4	-1.8	-1.8
Number of children fathered	2.8	3.1	3.5	-1.7	-1.9
Knee pain experienced in last month	2.8	4.4	4.6	-2.1	-2.0
Pain experienced in last month	2.8	4.7	5.2	2.3	2.1
Arm predicted mass (left)	2.8	14.3	18.1	-3.3	-4.2
Other serious medical condition/disability diagnosed by doctor	2.7	3.5	3.8	1.9	1.8
Leg predicted mass (left)	2.7	14.4	17.7	-3.3	-4.2
Father’s age at death	2.7	3.7	4.7	1.6	2.2
Arm predicted mass (right)	2.7	13.6	17.1	-3.2	-4.1
Prostate Cancer	2.6	3.6	3.6	1.9	1.9
Leg fat-free mass (left)	2.6	13.6	17.0	-3.2	-4.1
Hair/balding pattern: Pattern 3	2.6	3.9	4.7	-1.7	-2.2
Arm fat-free mass (left)	2.6	13.3	16.9	-3.1	-4.1
Mean Putamen Volume	2.5	2.9	3.6	-1.5	-1.9
Primary Biliary Cirrhosis	2.5	3.5	4.0	-1.8	-2.0
Fluid intelligence score	2.5	5.1	6.7	-2.6	-1.9
Arm fat-free mass (right)	2.5	13.0	16.2	-3.1	-4.0
Qualifications: nursing, teaching	2.5	3.9	4.6	1.8	2.1
Neuroticism (Nagel 2018)	2.4	5.7	7.1	2.1	2.7
Alzheimer’s Disease (in mother)	2.4	2.9	3.0	1.6	1.7
Hypothyroidism (self reported)	2.4	5.5	7.0	2.7	2.0
Hearing aid user	2.4	2.8	3.1	-1.5	-1.8
Triglycerides	2.3	3.8	4.7	-1.7	-2.2
Basal metabolic rate	2.3	12.8	16.4	-3.0	-4.0
Diastolic blood pressure, automated reading	2.3	7.2	9.0	-2.3	-3.0
Impedance of arm (right)	2.2	10.1	10.7	3.1	3.3
Forced expiratory volume in 1-second (FEV1)	2.2	7.4	8.7	2.5	2.9
Blood clot in the leg (DVT)	2.2	2.9	3.0	-1.7	-1.7
Leg predicted mass (right)	2.2	11.6	14.2	-3.0	-3.8
Medication: Cholesterol lowering	2.1	3.2	4.4	-1.4	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.8	8.7	2.2	2.9
Hypertension (Self-reported)	2.1	5.7	7.8	-1.9	-2.8
Leg fat-free mass (right)	2.1	11.1	13.8	-2.9	-3.7
Impedance of whole body	2.1	10.7	11.6	3.1	3.4
Stomach or abdominal pain in last month	2.0	2.5	2.7	1.5	1.6
Average weekly champagne plus white wine intake	2.0	2.8	3.2	-1.8	-1.5
Heart disease (siblings)	2.0	2.5	2.7	-1.5	-1.6
High blood pressure	1.9	5.4	7.5	-1.8	-2.7
Nervous feelings	1.9	3.6	5.4	1.3	2.3
Had other major operations	1.9	2.3	3.1	-1.3	-1.8
Irritability	1.9	3.3	4.5	1.4	2.1
Deep venous thrombosis (DVT) (self-reported)	1.9	2.4	2.6	-1.5	-1.6
Ever used hormone-replacement therapy (HRT)	1.8	2.3	3.1	1.8	1.2
Impedance of leg (left)	1.8	8.6	9.4	2.8	3.1
Impedance of arm (left)	1.8	8.4	8.8	2.8	3.0
Whole body water mass	1.8	10.1	12.8	-2.7	-3.6
Medication: Blood pressure	1.8	3.5	5.2	-1.3	-2.3
High cholesterol (Self-reported)	1.8	3.1	3.7	-1.6	-1.9
Pack years of smoking	1.8	2.6	3.4	-1.4	-1.8
Neuroticism (2016)	1.7	2.5	3.2	1.4	1.8
Tense / ‘highly strung’	1.7	2.9	3.5	1.5	1.9
Medication: Allopurinol	1.7	2.3	3.1	1.3	1.8
Whole body fat-free mass	1.7	9.8	12.4	-2.7	-3.5
Ever had bowel cancer screening	1.7	2.0	2.5	-1.2	-1.6
Osteoporosis (self-reported)	1.7	2.1	3.0	-1.1	-1.7
Cholesterol lowering medication	1.7	2.5	3.5	-1.3	-1.9
Hair/balding pattern: Pattern 4	1.6	3.8	4.0	1.9	2.0
Wheeze or whistling in the chest in last year	1.6	2.8	2.9	-1.7	-1.7
Impedance of leg (right)	1.5	7.1	7.9	2.5	2.8
Financial difficulties in last 2 years	1.5	2.0	2.6	-1.2	-1.6
Medication: Bendroflumethiazide	1.5	2.3	3.9	-0.9	-2.0
Verbal and Numeric Reasoning (VNR)	1.4	3.3	4.9	-2.2	-1.3
Type 2 Diabetes (T2D) (2012)	1.4	1.6	2.8	-0.6	-1.7
Vitamin and mineral supplements	1.4	1.9	2.0	1.4	1.4
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	2.0	-1.1	-1.4
Age at first live birth	1.4	2.5	2.9	1.7	1.4
Shortness of breath walking on level ground	1.4	1.7	1.7	-1.3	-1.3
Medication for cholesterol	1.4	2.1	2.9	1.1	1.7
Pack years adult smoking proportion	1.3	2.1	2.7	-1.2	-1.6
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	3.0	1.1	1.7
Medication: Blood pressure	1.3	2.3	3.4	-1.1	-1.9
Handedness (chirality/laterality): Left-handed	1.3	1.6	1.8	-1.3	-1.2
Crohns Disease (2012)	1.2	1.9	2.9	1.0	1.7
Had menopause	1.2	1.5	1.9	-1.0	-1.4
Trunk fat-free mass	1.2	6.8	8.9	-2.2	-3.0
Lung cancer (father)	1.2	1.4	1.6	1.1	1.3
Trunk predicted mass	1.2	7.0	9.1	-2.2	-3.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.6	1.7	1.3	1.2
Medication: Aspirin	1.2	1.5	1.8	-1.1	-1.3
Supplements: Fish oil (including cod liver oil)	1.2	1.6	1.9	1.1	1.4
Body Mass Index (BMI) (2010)	1.1	1.6	1.8	-1.2	-1.3
Sensitivity / hurt feelings	1.1	1.9	1.9	1.3	1.4
Serious illness, injury or assault to yourself	1.1	1.3	1.4	1.2	1.1
Breastfed as a baby	1.1	1.4	1.5	-1.1	-1.2
Eye problems/disorders: None of the above	1.1	1.3	1.4	-1.1	-1.2
Medication: Ibuprofen	1.1	1.3	1.5	-1.1	-1.2
Mean time to correctly identify matches	1.1	2.1	3.3	1.8	1.0
Illnesses of father: High blood pressure	1.1	1.4	1.7	-1.3	-1.0
Crohns Disease (2017)	1.0	2.2	3.2	1.1	1.8
Breast Cancer	1.0	2.4	3.1	-1.3	-1.8
Medication: Metformin	1.0	1.4	1.6	-1.1	-1.3
Neuroticism score	1.0	2.1	2.3	1.4	1.5
Medication: Seretide 50 evohaler	1.0	1.2	1.8	0.7	1.4
Overall health rating	1.0	2.0	2.8	-1.1	-1.7
Miserableness	1.0	1.8	2.0	-1.2	-1.4
Commuting to job workplace: Cycle	1.0	1.2	1.5	-1.2	-1.0
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	1.7	0.8	1.3
Rheumatoid Arthritis	0.9	1.3	1.8	1.3	0.8
Neuroticism	0.9	2.1	2.7	1.2	1.6
Hearing difficulty/problems with background noise	0.9	1.4	1.7	-1.1	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	1.7	-1.3	-1.1
Mouth/teeth dental problems: Dentures	0.9	1.4	1.8	1.4	1.0
Illnesses of mother	0.9	1.2	2.0	0.5	1.4
Loud music exposure frequency	0.9	1.0	1.1	-1.0	-0.9
Back pain experienced in last month	0.9	1.4	1.9	-1.4	-0.9
Maternal smoking around birth	0.8	1.2	1.5	-1.2	-0.9
Mouth/teeth dental problems	0.8	1.3	1.4	1.2	1.1
Medication: Omeprazole	0.8	1.0	1.5	0.7	1.2
Pulse rate, automated reading	0.8	2.7	3.1	-1.8	-1.5
Major Depression (MDD)	0.7	0.8	1.5	-1.2	-0.4
LDL Cholesterol	0.7	1.1	1.3	1.1	0.9
Number of treatments/medications taken	0.7	1.3	1.5	-1.0	-1.2
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	1.3	0.7	1.2
Allergy	0.7	1.5	2.8	1.7	0.5
Asthma	0.7	1.5	2.1	-1.4	-0.9
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	1.1	-0.8	-1.1
Number of full sisters	0.7	0.9	1.0	-1.0	-0.9
Ever taken oral contraceptive pill	0.7	0.7	1.0	-1.0	-0.7
Bipolar Disorder (2018)	0.6	1.0	1.6	-1.3	-0.6
Schizophrenia (2018)	0.6	1.3	1.9	0.8	1.4
Alzheimer’s Disease (in father)	0.6	0.6	0.8	0.7	0.9
Reaction Time	0.6	1.2	1.9	1.4	0.7
Heart attack	0.6	0.7	1.1	-0.6	-1.0
Time employed in main current job	0.6	0.7	0.7	0.8	0.8
Qualifications: A levels/AS levels or equivalent	0.6	1.4	2.6	0.5	1.6
Birth weight of first child	0.6	1.1	1.1	-1.0	-1.1
Qualifications: College or University degree	0.6	2.0	3.2	0.9	1.8
Angina (self-reported)	0.6	0.8	1.2	-0.7	-1.1
Number of operations (self-reported)	0.6	0.9	1.3	-0.6	-1.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	0.7	0.8	0.8
Heart attack/myocardial infarction (self-reported)	0.6	0.8	1.2	-0.6	-1.1
Intelligence (Savage-Jansen 2018)	0.5	1.4	2.7	-1.6	-0.4
Irritable Bowel Disease (IBD)	0.5	1.3	2.1	0.7	1.4
Coronary Artery Disease (CAD)	0.5	0.6	0.8	-0.9	-0.6
Medication for hormone replacement therapy	0.5	0.5	0.6	0.8	0.6
Townsend deprivation index at recruitment	0.5	0.7	1.2	-1.1	-0.5
Hayfever, allergic rhinitis or eczema	0.5	1.0	2.0	0.3	1.4
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.3	-0.1	1.1
Headache pain in last month	0.5	0.9	1.1	-1.0	-0.8
Hypothyroidism/myxoedema (self-reported)	0.5	1.1	1.7	1.3	0.6
Worry too long after embarrassment	0.5	0.8	1.0	0.8	1.0
Emphysema/chronic bronchitis	0.5	0.6	0.6	-0.8	-0.8
Diabetes diagnosed by doctor	0.5	0.8	0.9	-0.8	-0.9
Medication: Atorvastatin	0.5	0.7	1.2	-0.4	-1.1
Ever depressed for a whole week	0.5	0.6	0.9	0.6	0.9
HDL Cholesterol	0.4	0.7	1.3	0.4	1.1
Heel T-Score	0.4	3.2	5.8	0.8	2.4
Allergy or Eczema	0.4	1.1	2.1	0.3	1.4
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.3	-0.3	-1.2
Lung FEV1/FVC ratio	0.4	1.8	3.5	-1.9	-0.4
Ever had hysterectomy (womb removed)	0.4	0.5	0.9	0.0	-1.0
Angina	0.4	0.5	0.8	-0.4	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	0.6	0.7	0.8
Diabetes (self-reported)	0.4	0.6	0.7	-0.7	-0.9
Comparative height size at age 10	0.4	2.1	2.2	1.5	1.4
Suffer from ‘nerves’	0.4	0.6	1.1	0.4	1.1
Family relationship satisfaction	0.4	0.5	0.7	-0.9	-0.6
Supplements: Vitamin C	0.4	0.5	0.8	0.5	0.9
Average weekly red wine intake	0.4	0.6	0.8	0.9	0.6
Medication: Aspirin	0.4	0.6	0.9	-0.5	-1.0
Financial situation satisfaction	0.4	0.5	0.5	-0.7	-0.7
Risk taking	0.4	0.6	0.7	-0.8	-0.7
Alcohol drinker status: Previous	0.4	0.5	0.6	-0.6	-0.8
Height	0.3	5.6	8.9	-1.5	-3.0
Current tobacco smoking	0.3	0.5	0.6	-0.6	-0.8
Medication: Levothyroxine sodium	0.3	0.6	1.0	1.0	0.3
Falls in the last year	0.3	0.4	0.4	-0.6	-0.6
Happiness	0.3	0.3	0.4	0.5	0.7
Noisy workplace	0.3	0.3	0.4	0.5	0.6
Medication: Amlodipine	0.3	0.4	0.4	-0.7	-0.6
Alcohol intake frequency.	0.3	0.7	1.4	-0.2	-1.2
Chest pain or discomfort	0.3	0.5	0.5	-0.7	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.6	-0.4	-0.8
Illnesses of father: Heart disease	0.3	0.4	0.6	0.8	0.4
Number of self-reported non-cancer illnesses	0.3	0.5	0.9	-0.3	-1.0
Mother’s age at death	0.3	0.4	0.7	0.8	0.3
Alcohol drinker status: Never	0.3	0.4	0.5	0.7	0.5
Basal cell carcinoma (self-reported)	0.3	0.4	0.7	-0.9	-0.2
Schizophrenia vs Biploar Disorder	0.2	0.2	0.2	0.5	0.4
Ulcerative Colitis	0.2	0.2	0.4	0.3	0.6
Blood Platelet Count	0.2	2.0	3.4	-1.8	-0.8
Respiratory disease	0.2	0.4	0.5	0.5	0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.4	0.1	0.6
Medication: Co-codamol	0.2	0.2	0.3	0.6	0.3
Taking other prescription medications	0.2	0.3	0.3	-0.5	-0.6
Supplements: Glucosamine	0.2	0.2	0.4	0.2	0.6
Sitting height	0.2	1.2	1.5	1.0	1.2
Alcohol usually taken with meals	0.2	0.3	0.3	0.6	0.4
Qualifications: None of the above	0.2	0.5	0.6	-0.7	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.3	0.5	0.5
Medication: Lansoprazole	0.2	0.2	0.3	0.5	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	0.3	0.5	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.3	0.4	0.5
Gout (self-reported)	0.2	0.2	0.2	0.5	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.4	0.6	0.1
Health satisfaction	0.2	0.2	0.4	0.2	-0.7
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.4	-0.1	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.3	-0.5	-0.5
Leg pain on walking	0.2	0.3	0.6	0.7	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	0.6	0.7	0.6
Commuting to job workplace: Walk	0.2	0.2	0.3	-0.3	0.5
Eye problems/disorders: Cataract	0.2	0.2	0.3	0.2	0.6
Breast cancer (self-reported)	0.2	0.2	0.3	0.5	0.4
Asthma (self-reported)	0.2	0.4	0.6	-0.8	-0.3
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.4	0.4	0.6
Medication: Paracetamol	0.2	0.3	0.4	-0.4	-0.6
Medication: Lisinopril	0.2	0.3	0.4	-0.4	-0.7
Bipolar Disorder or Schizophrenia	0.1	0.3	0.5	-0.2	0.7
Ulcerative Colitis (UC)	0.1	0.3	0.5	0.2	0.7
Bipolar Disorder (2011)	0.1	0.1	0.2	-0.0	0.4
HbA1C	0.1	0.2	0.3	0.1	0.5
Blood Eosinophil Count	0.1	0.6	0.7	-0.7	0.8
Blood White Count	0.1	0.7	1.3	-1.1	0.3
Chronotype (morning person)	0.1	0.2	0.4	0.6	-0.1
Tanning	0.1	0.6	0.8	0.6	0.9
Supplements: Zinc	0.1	0.1	0.2	-0.0	0.5
Diabetes (mother)	0.1	0.1	0.1	0.4	-0.4
Fed-up feelings	0.1	0.1	0.2	-0.4	-0.4
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	-0.2	-0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	-0.4	-0.1
High blood pressure (mother)	0.1	0.1	0.2	0.5	-0.2
Hair/balding pattern: Pattern 2	0.1	0.1	0.1	-0.2	0.4
Pulse rate	0.1	0.1	0.2	-0.2	-0.4
Depression (self-reported)	0.1	0.1	0.1	0.2	0.2
Standing height	0.1	0.6	1.0	1.0	0.4
Length of working week for main job	0.1	0.1	0.2	-0.0	-0.5
Exposure to tobacco smoke at home	0.1	0.2	0.3	-0.1	-0.5
Pulse wave reflection index	0.1	0.1	0.1	0.3	-0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.3	-0.2	0.6
Medication: Paracetamol	0.1	0.2	0.3	-0.1	-0.6
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.1	-0.3	-0.4
Migraine (self-reported)	0.1	0.1	0.1	-0.3	-0.2
Heart disease (mother)	0.1	0.2	0.3	0.5	0.2
Had major operations	0.1	0.1	0.3	0.5	-0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.1	-0.4	-0.2
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.2	0.4	0.5
Loneliness, isolation	0.1	0.1	0.1	0.3	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	-0.1	0.5
Friendships satisfaction	0.1	0.2	0.4	-0.6	-0.0
Mineral and other dietary supplements	0.1	0.2	0.4	-0.1	-0.6
Smoking status: Current	0.1	0.2	0.3	-0.5	-0.5
Guilty feelings	0.1	0.2	0.2	-0.3	-0.5
Commuting to job workplace: Public transport	0.1	0.1	0.2	-0.3	-0.4
Average weekly beer plus cider intake	0.1	0.1	0.1	0.1	0.4
Age started oral contraceptive pill	0.1	0.1	0.1	0.4	0.4
Unable to work because of sickness or disability	0.1	0.1	0.2	0.3	-0.4
Supplements: Calcium	0.1	0.1	0.3	-0.5	-0.1
Depressed Affect (Nagel 2018)	0.0	0.1	0.1	0.4	0.1
Depression (Nagel 2018)	0.0	0.1	0.1	-0.3	-0.2
Ovarian Cancer	0.0	0.1	0.1	0.3	0.2
Age at First Birth	0.0	0.0	0.0	-0.1	0.0
Schizophrenia (2014)	0.0	0.1	0.2	-0.1	0.4
Systolic Blood Pressure	0.0	0.1	0.1	-0.3	-0.2
Hair Pigment	0.0	1.1	1.2	1.1	1.1
Average weekly spirits intake	0.0	0.0	0.1	-0.2	-0.1
Frequency of depressed mood in last 2 weeks	0.0	0.0	0.0	-0.2	-0.1
Systolic blood pressure, automated reading	0.0	0.0	0.1	-0.0	-0.3
Diabetes (father)	0.0	0.0	0.0	-0.2	0.2
Average weekly fortified wine intake	0.0	0.0	0.0	-0.1	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.0	0.2	-0.2
Age when periods started (menarche)	0.0	0.1	0.1	-0.2	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.0	0.0	0.2
Medication: Atenolol	0.0	0.1	0.1	0.3	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	-0.3	0.0
Alcohol intake versus 10 years previously	0.0	0.1	0.1	0.3	0.2
Pulse wave Arterial Stiffness index	0.0	0.0	0.1	0.2	-0.2
Peak expiratory flow (PEF)	0.0	0.0	0.0	-0.1	0.2
Medication: Ventolin 100micrograms inhaler	0.0	0.0	0.0	0.1	0.1
Exposure to tobacco smoke outside home	0.0	0.0	0.1	-0.2	-0.2
Pulse wave peak to peak time	0.0	0.0	0.0	-0.2	0.2
Medication for pain relief, constipation, heartburn	0.0	0.0	0.0	0.1	0.1
Neck or shoulder pain in last month	0.0	0.0	0.0	-0.2	-0.1
Age at last live birth	0.0	0.0	0.0	-0.0	-0.1
Mood swings	0.0	0.0	0.0	0.2	0.2
Long-standing illness, disability or infirmity	0.0	0.0	0.0	-0.1	-0.1
Medication: Gliclazide	0.0	0.0	0.0	0.2	-0.0

Hub : Genes

TRIM72

Models

Trait associations