Hub : Genes

TTC28

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Nerve Tibial 0.1330 0.0465 1.1e-03 0.032 NA 0.041 NA 0.064 0.00250 NA 0.00065 NA 2.5e-05
2 GTEx Skin Not Sun Exposed Suprapubic 0.1760 0.0720 3.7e-03 -0.001 NA -0.005 NA -0.005 0.38000 NA 0.84000 NA 9.5e-01
3 GTEx Testis 0.2880 0.0710 2.7e-06 0.041 NA 0.047 NA 0.051 0.00660 NA 0.00370 NA 2.6e-03
4 GTEx Thyroid 0.0950 0.0360 1.2e-03 0.002 NA 0.017 NA 0.014 0.20000 NA 0.01700 NA 2.6e-02
5 TCGA Breast Invasive Carcinoma 0.0252 0.0111 7.5e-05 0.012 0.015 0.012 NA 0.011 0.00120 0.00037 0.00130 NA 1.9e-03
6 TCGA Head and Neck Squamous Cell Carcinoma 0.0446 0.0225 4.1e-03 0.010 0.017 0.006 NA 0.010 0.02300 0.00450 0.05600 NA 2.2e-02
7 TCGA Prostate Adenocarcinoma 0.0583 0.0283 1.0e-03 0.031 0.024 0.029 NA 0.027 0.00031 0.00130 0.00049 NA 7.4e-04
8 TCGA Testicular Germ Cell Tumors 0.1120 0.0590 3.9e-03 0.079 0.075 0.106 NA 0.072 0.00098 0.00130 0.00015 NA 1.6e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.5 0.8 2.6 -0.8 -1.0 -0.9 0.8 -0.0 -0.5 -1.6 0.4
Bipolar Disorder or Schizophrenia 0.2 0.6 2.1 1.4 1.2 -0.2 -0.6 -0.1 0.1 -0.7 0.1
Depressed Affect (Nagel 2018) 0.4 0.8 2.0 -0.2 1.2 -0.1 -0.8 -0.2 1.4 1.3 0.6
Depression (Nagel 2018) 1.1 1.6 7.4 1.3 1.0 0.6 -2.7 -0.8 1.2 0.6 -0.3
Intelligence (Savage-Jansen 2018) 0.4 1.3 3.3 -0.8 -1.8 -1.5 0.4 0.8 0.6 1.3 1.2
Neuroticism (Nagel 2018) 0.4 0.9 4.4 -1.2 0.3 -0.4 -0.7 -2.1 -0.8 -0.5 -0.3
Schizophrenia (2018) 0.9 1.8 6.3 2.5 2.4 0.4 -1.4 -0.1 0.5 0.4 -0.2
Schizophrenia vs Biploar Disorder 2.3 3.0 7.5 2.4 1.2 0.6 -0.7 1.4 2.7 2.5 0.3
Worry (Nagel 2018) 1.5 3.3 8.3 -2.0 -0.7 -0.4 -0.0 -2.9 -2.4 -2.7 -0.1
Alzheimer’s Disease (in mother) 0.9 1.1 2.4 0.6 -0.5 0.3 -0.5 -1.4 -1.6 -1.4 -1.1
Alzheimer’s Disease (in father) 1.3 1.4 3.6 1.1 1.9 1.3 -0.4 0.9 1.3 1.5 0.4
Alzheimer’s Disease (including proxy) 0.4 0.6 1.4 0.7 0.2 0.9 -0.3 -0.9 -1.2 -0.8 -0.8
Crohns Disease (2017) 0.8 1.8 5.4 -2.3 -0.7 -2.2 -0.7 -0.2 1.7 0.5 -0.3
Irritable Bowel Disease (IBD) 0.6 1.5 5.1 -2.1 -0.6 -2.3 -0.5 0.3 1.2 0.4 -0.2
Ulcerative Colitis (UC) 0.2 0.4 1.5 -1.1 -0.3 -1.2 0.2 0.7 0.2 0.1 0.3
Major Depression (MDD) 2.0 2.4 5.8 -2.2 -0.6 -1.6 -0.9 -2.4 -1.0 -1.7 -0.8
Reaction Time 3.6 6.9 23.1 -1.4 -0.7 -1.4 2.8 -2.5 -4.8 -3.5 -1.0
Verbal and Numeric Reasoning (VNR) 0.4 0.9 3.3 0.4 -0.7 -1.6 -0.1 0.8 0.5 1.8 0.4
Breast Cancer 4.1 9.8 32.8 1.4 2.4 0.5 2.5 5.7 0.9 3.1 4.6
Ovarian Cancer 6.6 8.7 20.9 -1.2 -4.0 -0.3 -2.9 -4.6 -0.4 -2.1 -4.3
Prostate Cancer 0.7 1.0 2.4 -0.0 0.7 -0.8 -1.0 -0.5 1.3 1.5 -1.1
Age at First Birth 1.6 2.4 4.6 -1.6 -0.8 -1.6 2.2 0.1 -2.0 -1.2 1.8
Bipolar Disorder (2011) 0.5 0.5 1.0 -0.5 -0.4 -1.0 -0.5 0.3 0.9 0.5 0.9
Body Mass Index (BMI) (2010) 0.9 1.3 3.3 0.7 0.1 -0.4 -0.8 1.6 1.8 1.8 0.3
Coronary Artery Disease (CAD) 2.1 2.4 7.7 -0.2 -0.6 0.1 1.5 2.8 0.9 1.3 2.6
Crohns Disease (2012) 1.3 2.0 10.8 -1.4 -1.2 -3.3 0.3 -0.0 0.9 1.1 0.2
Mean Putamen Volume 0.7 0.8 3.2 0.7 0.5 -0.1 -1.8 0.2 1.1 0.7 -1.0
Fasting Glucose 1.9 2.2 7.9 2.8 1.3 0.4 -0.4 1.7 1.1 1.9 0.5
HbA1C 0.3 0.4 1.0 -0.0 0.8 -1.0 0.1 -0.5 0.2 0.6 -0.8
HDL Cholesterol 2.0 3.3 8.8 -0.2 -0.6 1.3 -0.3 -3.0 -2.3 -2.3 -2.2
LDL Cholesterol 0.3 0.4 1.1 -0.2 -1.0 0.8 0.5 0.6 0.8 0.6 -0.3
Lupus 2.7 4.0 12.2 1.6 2.3 0.0 0.3 3.5 1.1 2.6 2.1
Neuroticism (2016) 1.9 2.7 8.0 -0.2 1.0 1.3 -2.8 -2.4 1.7 0.1 -1.5
Primary Biliary Cirrhosis 0.9 1.3 4.6 0.7 -0.4 0.5 0.3 2.1 1.4 1.6 0.5
Rheumatoid Arthritis 1.9 2.6 7.2 -0.3 0.2 -2.1 2.2 1.5 -1.3 0.3 2.7
Schizophrenia (2014) 1.5 3.4 11.1 3.1 3.3 0.4 -2.2 0.0 0.9 0.4 0.1
Triglycerides 1.4 2.3 5.8 0.6 0.6 -0.6 -0.6 2.1 2.4 2.4 1.1
Type 2 Diabetes (T2D) (2012) 2.4 2.8 6.8 2.6 1.5 1.8 -1.8 0.7 1.6 1.8 -0.3
Ulcerative Colitis 0.3 0.5 2.5 -1.6 -0.6 -0.6 0.2 -0.5 -0.3 -0.1 -0.5
Blood Eosinophil Count 0.6 4.6 11.2 -0.9 -2.0 -0.7 -3.1 -3.3 0.3 -0.7 -3.3
Blood Platelet Count 1.1 12.2 35.3 -2.6 -2.4 1.2 -4.2 -5.9 0.1 -3.1 -4.6
Blood Red Count 1.3 12.5 27.9 -5.3 -3.6 -3.5 -0.2 -4.6 -2.5 -3.6 -2.5
Blood White Count 0.3 2.3 5.1 -1.0 -1.3 -2.2 -1.1 1.0 2.2 1.6 1.1
Heel T-Score 2.0 16.3 47.2 -2.6 0.0 -6.9 3.2 4.4 1.1 2.4 6.3
BMI 0.7 3.9 10.5 2.8 0.7 -0.9 -1.0 1.6 2.8 3.2 -0.2
Height 0.6 11.2 29.6 3.4 5.4 -0.7 -4.5 3.2 3.3 2.5 1.0
Waist Hip Ratio (WHR) 0.9 4.3 9.8 -0.7 0.9 -1.2 -3.1 -2.5 3.1 0.9 -2.2
Systolic Blood Pressure 0.3 1.6 5.2 0.9 -0.3 -0.0 -1.8 -1.8 2.3 0.3 -0.2
Smoking Status 3.3 8.0 18.0 4.2 2.4 2.8 -1.8 2.2 3.3 3.6 -0.7
Allergy or Eczema 4.1 10.8 29.1 -3.5 -1.8 -1.5 -2.0 -5.4 -2.2 -4.4 -3.4
Cardiovascular Disease 1.0 3.2 8.1 1.7 2.0 1.5 -0.4 1.1 2.8 2.5 1.1
Hypothyroidism (self reported) 0.3 0.8 1.8 -0.7 -0.0 -1.3 -1.0 -0.5 0.3 -0.9 -1.3
Respiratory disease 0.8 1.7 6.1 -0.5 -1.1 -0.2 -1.3 -2.5 -0.3 -0.9 -1.9
Type 2 Diabetes (T2D) (2018) 1.9 3.6 11.8 1.8 0.7 2.2 0.5 3.4 1.4 2.0 1.6
Lung FEV1/FVC ratio 0.5 2.6 9.0 -3.0 0.8 -0.5 0.9 1.1 -0.9 -1.3 2.5
Lung FVC 1.1 5.8 11.6 2.8 3.2 1.7 -3.2 -1.4 1.3 0.0 -3.4
Neuroticism 0.3 0.7 2.9 -1.5 -0.5 -0.1 -0.2 -1.7 -0.2 -0.1 0.2
Chronotype (morning person) 3.0 6.9 21.7 -0.3 1.2 0.5 -0.5 -4.7 -3.1 -2.1 -4.1
Hair Pigment 0.1 2.6 5.2 -1.1 -2.3 -1.8 -1.6 -1.8 1.8 0.0 -1.3
Tanning 0.2 3.0 9.3 -0.9 -1.0 -0.2 -1.5 -3.0 -1.1 -1.1 -2.8
Hand grip strength (left) 1.6 4.2 8.1 2.8 2.2 0.3 -1.8 2.0 2.1 2.9 0.4
Number of treatments/medications taken 1.8 3.3 7.2 -0.6 -0.0 1.8 -2.6 -1.7 2.7 1.0 -2.2
Average weekly spirits intake 0.1 0.1 0.5 0.6 0.0 0.2 -0.3 -0.7 0.1 0.2 -0.3
Sensitivity / hurt feelings 1.5 2.6 8.2 0.4 0.2 1.7 -2.9 -2.0 1.1 0.3 -2.1
Frequency of depressed mood in last 2 weeks 1.2 1.6 6.8 0.2 0.5 0.5 -2.6 -1.6 1.3 0.6 -1.1
Hearing difficulty/problems: Yes 1.3 1.9 5.2 0.8 1.2 0.5 -2.3 -1.9 -0.3 -1.1 -1.7
Relative age of first facial hair 0.5 1.1 3.2 0.4 -0.8 0.8 -1.8 -1.2 -0.0 -0.7 -1.5
Other serious medical condition/disability diagnosed by doctor 2.4 3.2 8.5 1.0 0.9 -0.0 -0.3 2.9 2.0 1.9 2.6
Ever used hormone-replacement therapy (HRT) 0.9 1.1 2.0 1.4 1.3 1.0 0.5 1.0 -0.8 -0.8 1.3
Ever had hysterectomy (womb removed) 0.6 0.7 2.8 0.6 0.0 0.5 -0.5 -0.5 -1.0 -1.7 -0.6
Systolic blood pressure, automated reading 0.5 1.6 5.7 1.2 0.4 0.6 -2.1 -0.5 2.4 0.3 -0.6
Eye problems/disorders: Diabetes related eye disease 1.8 2.0 6.3 0.9 0.3 1.2 1.2 2.5 0.8 1.0 2.0
Angina 0.8 1.0 2.0 1.2 0.3 0.1 -1.1 -0.5 1.3 1.4 -1.2
Medication for hormone replacement therapy 1.3 1.5 4.7 -1.6 -2.2 -0.1 0.8 -0.6 -0.8 -1.2 1.2
Vitamin and mineral supplements 0.6 0.8 3.2 0.1 0.1 -1.8 1.1 0.0 -1.4 -0.4 0.3
Supplements: Zinc 0.6 0.7 2.1 -1.4 -0.9 0.1 -0.2 -1.0 -0.4 -0.9 -0.6
Medication: Co-codamol 2.1 2.4 9.1 0.5 -0.5 3.0 -1.6 -0.1 1.9 1.2 -1.5
Medication: Metformin 1.0 1.4 5.2 0.3 -0.1 0.9 0.5 2.3 1.1 0.8 1.7
Diabetes (father) 1.5 1.9 3.5 -1.9 -1.7 -1.6 1.6 0.4 -0.2 0.4 1.7
Diabetes (mother) 0.5 0.6 1.9 -0.9 -0.2 -0.6 0.4 0.0 -1.1 -0.9 1.4
Severe depression (siblings) 1.5 1.6 5.2 1.3 0.5 0.2 -2.3 -1.5 0.7 -0.7 -1.7
Pack years adult smoking proportion 0.6 1.0 4.6 2.1 1.3 0.2 0.6 0.6 -0.2 0.5 0.8
Impedance of leg (right) 0.3 1.3 2.4 0.9 -1.4 1.6 -1.5 -0.3 0.6 0.3 -1.5
Leg fat-free mass (left) 1.1 5.8 11.0 2.9 3.3 -0.4 -1.4 2.6 2.8 3.2 0.8
Trunk fat percentage 0.8 3.3 10.1 3.2 0.8 0.0 -1.1 2.5 2.0 1.7 0.9
Hand grip strength (right) 0.5 1.4 4.5 2.1 1.3 0.5 -1.5 0.6 0.4 1.3 -0.2
Townsend deprivation index at recruitment 1.3 1.8 5.5 2.4 2.0 1.2 -1.1 1.3 0.5 0.5 -0.5
Current tobacco smoking 1.6 2.7 6.8 2.6 1.8 2.1 -1.1 1.4 1.7 0.9 0.2
Average weekly fortified wine intake 0.1 0.1 0.4 -0.5 -0.6 0.2 -0.3 0.1 0.0 -0.4 0.1
Maternal smoking around birth 2.5 3.6 8.2 2.9 1.8 1.0 -2.7 1.0 2.0 1.8 0.8
Fed-up feelings 0.3 0.5 1.9 0.3 0.7 -0.3 -0.4 0.6 0.8 1.4 0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.7 3.6 1.0 0.9 0.4 -1.9 -0.2 0.3 0.3 -0.2
Relative age voice broke 0.5 0.7 2.6 0.4 -0.9 1.6 -1.1 0.3 0.7 -0.4 -0.4
Taking other prescription medications 2.8 4.3 10.1 1.2 0.3 2.5 -3.2 -1.3 2.5 1.0 -2.7
Age when periods started (menarche) 0.9 2.1 5.6 -1.4 -0.3 -2.4 0.8 -1.2 -1.8 -1.9 0.4
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.0 0.0 -0.5 0.5 -1.2 -0.5 0.6 -1.4 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 2.1 4.7 24.0 -1.7 0.4 -4.9 0.7 1.2 0.0 0.4 2.9
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 2.9 -0.2 1.7 -0.0 0.0 -0.5 -0.6 0.0 -0.7
Qualifications: CSEs or equivalent 0.8 1.0 3.4 0.4 0.3 -0.0 -1.8 -1.3 0.4 0.0 -1.5
Serious illness, injury or assault to yourself 1.7 2.1 5.6 1.1 2.0 0.3 -1.8 0.8 2.4 1.4 -0.3
High blood pressure 1.7 4.6 12.0 2.1 1.1 3.2 -0.7 1.2 3.5 2.5 0.8
Hayfever, allergic rhinitis or eczema 4.2 9.1 24.3 -3.1 -1.1 -2.1 -0.8 -4.9 -3.0 -3.9 -2.8
Multivitamins +/- minerals 1.4 1.8 5.0 -0.4 -0.6 2.2 -2.1 -0.1 1.9 0.6 -0.6
Stomach or abdominal pain in last month 1.8 2.3 7.8 -0.9 -0.7 -0.9 -0.2 -2.1 -1.8 -2.8 -0.8
Supplements: Glucosamine 1.1 1.5 5.0 0.3 -0.9 1.2 -0.7 0.5 2.2 1.8 -0.7
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 3.3 -0.7 1.1 -0.6 0.1 1.1 0.2 -0.2 1.8
Medication: Atenolol 0.9 1.1 2.9 1.5 -0.4 1.4 -0.7 0.2 1.7 0.9 -0.7
Medication: Levothyroxine sodium 0.4 0.7 1.9 -0.1 0.6 -0.6 -0.6 -1.2 -0.6 -1.1 -1.4
Sitting height 0.7 4.9 12.5 1.4 2.0 -1.8 -3.5 -0.2 2.8 2.4 -2.0
Chronic bronchitis/emphysema (father) 1.1 1.3 3.9 -0.8 -1.5 -2.0 1.3 0.1 -1.2 -0.5 0.6
High blood pressure (mother) 0.5 0.7 2.0 0.5 -0.6 0.9 -0.9 -0.2 1.4 1.0 -0.4
Body mass index (BMI) 0.5 2.1 5.3 1.9 0.9 -0.5 -0.6 1.3 2.2 2.3 0.1
Impedance of leg (left) 0.4 1.8 3.9 0.2 -2.0 1.3 -1.8 -1.1 -0.0 -0.7 -2.0
Leg predicted mass (left) 1.1 6.0 11.4 2.9 3.4 -0.5 -1.4 2.6 2.8 3.3 0.8
Trunk fat mass 1.2 5.2 11.6 3.4 1.8 -0.3 -1.8 2.7 2.9 2.7 0.7
Waist circumference 1.1 4.0 12.3 1.8 1.8 -1.0 -2.3 1.2 3.5 2.4 -0.1
Number of incorrect matches in round 0.5 0.8 1.9 -0.0 1.4 0.4 0.6 0.4 -1.0 -0.8 1.3
Past tobacco smoking 2.2 4.0 8.2 -2.8 -0.8 -1.8 1.6 0.4 -2.2 -2.9 2.2
Alcohol usually taken with meals 2.0 3.3 7.5 -2.7 -1.1 -2.4 1.6 1.4 0.0 0.6 2.6
Nervous feelings 0.8 1.6 5.3 -1.3 -0.4 0.7 -0.9 -1.7 -1.1 -2.3 -0.0
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 3.5 0.2 1.0 1.4 -1.9 -1.6 -0.0 -0.4 -0.7
Hearing difficulty/problems with background noise 1.4 2.2 5.8 1.7 1.9 1.4 -2.4 0.5 1.6 0.6 -0.8
Hair/balding pattern: Pattern 2 1.5 1.9 5.3 1.2 2.3 -0.9 1.0 1.8 -0.3 1.6 1.1
Had menopause 2.0 2.5 7.7 0.1 0.8 -1.2 1.9 2.4 -0.5 0.4 2.8
Had other major operations 0.4 0.5 1.9 -0.3 -0.2 0.3 -1.4 -0.7 0.8 -0.6 -0.4
Forced vital capacity (FVC) 1.2 4.6 9.4 2.7 3.1 1.6 -2.8 -0.3 1.4 1.3 -2.4
Heel bone mineral density (BMD) T-score, automated (right) 2.4 5.5 27.2 -0.9 1.0 -5.2 0.8 1.9 0.4 1.5 2.8
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 2.4 -0.5 -1.1 -0.5 -1.6 -0.9 1.1 -0.1 -0.6
Qualifications: None of the above 0.5 1.1 2.5 1.6 1.5 1.4 -1.2 0.4 0.7 -0.5 -0.1
Financial difficulties in last 2 years 0.6 0.8 2.0 0.4 0.7 -0.9 -1.4 0.1 1.4 0.7 0.6
Mouth/teeth dental problems 0.5 0.7 2.0 -0.6 1.4 0.3 1.4 0.5 -0.6 0.2 0.8
Heart attack 0.8 1.0 3.8 0.1 -0.6 -1.1 -0.3 0.8 1.4 2.0 0.1
Allergy 3.3 7.7 23.2 2.9 1.1 1.5 0.3 4.8 2.8 3.1 2.9
Pain all over the body in last month 1.3 1.4 7.0 1.3 0.3 2.6 -0.4 0.6 1.4 0.4 -0.5
Diabetes (self-reported) 1.6 2.5 8.2 0.8 0.5 1.6 0.6 2.9 1.3 1.8 1.8
Hayfever/allergic rhinitis (self-reported) 2.7 3.5 13.2 -0.9 -0.0 -0.9 -1.7 -3.6 -1.2 -2.1 -2.2
Medication: Ramipril 0.5 0.7 3.3 1.8 -0.2 -0.0 -0.9 0.3 0.7 1.0 0.2
Medication: Simvastatin 0.2 0.4 1.4 -0.1 0.3 0.6 -0.5 0.7 1.2 0.3 -0.4
Fluid intelligence score 0.7 1.5 5.8 -0.9 -1.4 -2.4 0.9 0.4 -1.0 0.6 0.9
Illnesses of siblings 1.0 1.4 5.6 -0.4 1.2 0.3 0.7 -0.9 -2.4 -1.4 -1.1
Neuroticism score 0.4 0.8 2.9 -0.9 -0.7 -0.4 -1.2 -1.7 0.6 0.5 -0.1
Weight 1.1 5.6 11.4 2.9 2.6 -0.7 -1.8 2.2 3.2 3.4 0.3
Impedance of arm (right) 0.4 1.8 6.0 0.8 -0.7 0.6 0.6 0.5 -2.4 -2.3 1.0
Arm fat percentage (right) 0.8 3.2 7.5 2.7 1.0 -0.3 -0.6 2.4 2.2 2.3 1.0
Trunk fat-free mass 1.4 8.2 21.8 2.1 3.7 -1.1 -2.1 1.9 4.1 4.7 0.0
Hip circumference 0.9 3.9 9.1 3.0 1.4 0.1 -1.1 2.4 2.5 2.5 0.7
Time employed in main current job 1.6 1.9 5.4 -0.6 -1.0 0.0 -1.3 -2.3 -0.8 -0.8 -2.2
Alcohol intake versus 10 years previously 0.2 0.3 1.3 0.7 0.4 1.1 0.3 -0.3 0.2 0.3 -0.2
Father’s age at death 1.7 2.3 5.9 -2.4 -0.9 -1.5 1.6 0.4 -0.2 -1.2 2.4
Worrier / anxious feelings 3.3 6.2 15.8 -4.0 -2.8 -0.6 -0.7 -3.4 -1.5 -3.2 -1.4
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.7 2.3 1.0 1.0 1.5 -0.9 0.6 0.5 0.3 -0.4
Falls in the last year 0.3 0.4 0.9 0.1 0.8 -0.7 -0.5 -0.9 -0.9 -0.1 -0.6
Hair/balding pattern: Pattern 3 0.9 1.4 4.9 -0.8 -1.5 2.2 0.6 0.3 -0.7 -1.5 -0.5
Number of live births 0.6 0.9 3.8 0.4 -0.3 -0.3 -1.4 0.2 2.0 0.8 -0.4
Forced expiratory volume in 1-second (FEV1) 0.9 2.9 9.2 1.5 3.0 1.3 -2.6 0.2 1.0 0.6 -1.4
Pulse rate 1.5 2.6 11.8 0.9 1.6 3.4 -1.3 0.1 1.0 -0.3 -1.6
Happiness 0.3 0.4 1.8 0.0 0.0 1.4 0.3 -0.1 -0.9 -0.7 -0.0
Noisy workplace 1.9 2.4 8.0 0.2 1.1 2.8 -1.4 -1.7 0.3 -0.5 -2.1
Qualifications: A levels/AS levels or equivalent 2.4 5.3 12.0 -2.7 -1.2 -1.8 3.5 0.3 -2.9 -2.3 2.2
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 3.5 -0.1 0.4 -1.0 -0.7 -1.9 0.7 -0.0 -1.3
Mouth/teeth dental problems: Dentures 0.3 0.5 1.4 0.6 0.3 -0.8 -1.2 -0.2 0.5 0.5 -1.1
Asthma 1.2 2.4 9.6 -0.9 -0.5 -0.3 -1.3 -3.1 -0.6 -1.3 -2.1
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 2.0 0.4 0.5 0.4 -1.4 -0.2 0.3 -0.8 -0.1
Medication: Cholesterol lowering 0.6 1.0 2.6 -0.8 0.4 -0.6 -1.0 0.1 1.6 1.6 -0.5
Depression (self-reported) 1.1 1.3 5.3 -0.5 -0.6 -0.2 -0.4 -2.3 -0.8 -1.7 -0.6
Medication: Lansoprazole 1.2 1.4 2.7 0.3 1.1 1.7 -1.3 -0.3 1.6 1.3 -1.1
Prospective memory result 0.4 0.4 1.0 -0.3 -0.6 1.0 -0.7 0.2 0.7 -0.8 0.7
Lung cancer (father) 1.8 2.1 7.1 -0.9 -1.0 -0.4 1.2 -1.7 -2.7 -1.9 -0.7
Illnesses of mother 0.2 0.3 1.4 -0.1 1.2 -0.2 0.5 0.5 -0.2 -0.0 0.5
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.1 11.4 1.4 3.4 1.1 -2.5 -0.0 0.9 0.7 -1.6
Pulse wave Arterial Stiffness index 0.7 0.8 2.0 0.8 0.1 -0.1 -1.1 0.5 1.4 1.3 -0.8
Impedance of arm (left) 0.8 3.5 10.8 0.2 -1.3 1.1 1.1 0.4 -3.3 -3.3 1.5
Arm fat mass (right) 1.3 5.4 11.5 3.4 1.9 -0.2 -1.3 2.5 3.0 3.3 0.6
Trunk predicted mass 1.4 8.2 21.8 2.2 3.7 -1.1 -2.0 2.0 4.0 4.7 0.1
Standing height 0.7 6.7 15.8 2.8 4.0 -0.4 -2.8 2.3 2.8 3.0 0.4
Length of working week for main job 2.7 3.0 8.8 -0.1 0.1 -1.4 1.8 2.8 -1.6 0.1 3.0
Exposure to tobacco smoke at home 0.4 0.4 1.3 0.3 0.8 0.6 -0.8 -0.4 0.5 0.3 -1.1
Breastfed as a baby 1.0 1.2 4.4 1.3 0.6 -0.1 -2.1 0.4 1.0 0.6 -1.3
Tense / ‘highly strung’ 0.7 1.2 3.8 -0.2 -1.2 0.8 -1.6 -1.9 0.1 -0.6 -0.9
Seen doctor (GP) for nerves, anxiety, tension or depression 1.6 2.4 6.3 -1.4 -0.2 -0.9 -0.3 -2.5 -1.9 -2.2 -1.1
Hair/balding pattern: Pattern 4 1.4 3.4 7.4 2.6 0.7 2.6 0.7 2.7 0.7 -0.2 2.2
Birth weight of first child 0.6 1.2 3.0 0.8 1.3 1.0 0.5 -0.1 -0.1 1.7 -1.7
Peak expiratory flow (PEF) 1.5 3.4 9.2 0.2 1.4 1.8 -2.8 1.5 3.0 1.5 -0.7
Pulse wave reflection index 1.1 1.3 4.8 0.8 -0.6 -1.2 -0.0 1.3 1.4 2.2 0.2
Ever highly irritable/argumentative for 2 days 1.0 1.2 4.8 1.6 2.2 -0.4 -0.0 0.7 0.3 1.0 0.5
Loud music exposure frequency 1.8 1.9 4.6 1.3 -0.7 2.1 -1.3 -1.1 0.9 0.8 -2.1
Qualifications: O levels/GCSEs or equivalent 3.9 6.2 15.1 -2.8 -1.9 -0.9 2.7 -1.0 -3.9 -3.4 1.4
Mouth/teeth dental problems: Bleeding gums 0.9 1.1 2.9 1.5 -0.2 0.7 -1.7 0.0 1.7 0.7 -0.5
Blood clot in the leg (DVT) 0.9 1.2 3.1 -1.2 -1.0 -0.4 1.8 -0.9 -1.6 -0.1 -0.5
Medication: Paracetamol 1.8 3.1 10.4 -0.2 1.4 -0.2 -3.2 -1.7 1.1 0.3 -2.8
Headache pain in last month 1.4 2.5 6.1 -0.1 1.4 0.3 -1.9 -2.5 -1.0 -1.6 -2.2
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 6.4 0.3 -0.4 0.5 1.0 -0.3 -2.5 -2.2 -0.2
Glaucoma (self-reported) 4.1 4.8 15.5 1.4 2.4 2.1 -1.2 1.1 3.9 2.8 -0.5
Gout (self-reported) 3.2 4.3 10.3 2.8 3.0 1.2 0.2 1.1 2.2 3.2 0.3
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 1.3 -0.1 0.4 -0.8 -1.0 0.2 -0.1 -1.2 -0.8
Medication: Amlodipine 0.4 0.5 3.7 0.0 0.4 1.9 -0.2 0.2 0.5 0.1 0.1
Medication: Ventolin 100micrograms inhaler 1.3 1.7 6.0 -0.9 -1.0 -1.7 -0.8 -2.5 -0.1 -0.7 -1.4
Birth weight 1.2 2.6 11.7 -1.6 -1.3 -3.4 -1.4 -1.3 0.3 0.3 -0.8
Chronic bronchitis/emphysema (mother) 0.9 1.1 3.7 -0.0 0.8 -0.3 -1.9 -1.0 -0.5 -1.7 -0.5
High blood pressure (siblings) 1.9 2.7 6.9 1.6 -1.2 0.6 -2.2 -0.7 2.6 1.7 -1.2
Forced vital capacity (FVC), Best measure 1.3 4.7 13.1 2.5 3.6 1.2 -2.9 -0.6 1.0 0.9 -2.4
Body fat percentage 0.9 3.6 9.2 3.0 0.8 0.0 -1.2 2.6 2.4 2.2 0.7
Leg fat percentage (right) 1.3 4.6 11.8 2.6 0.7 0.2 -1.5 2.3 3.4 3.2 0.0
Arm fat-free mass (right) 1.3 6.6 14.3 2.5 3.2 -0.5 -2.3 1.8 3.6 3.8 -0.3
Exposure to tobacco smoke outside home 0.9 1.2 3.0 1.1 0.3 -0.0 -1.7 0.5 1.7 1.2 -0.5
Comparative body size at age 10 0.1 0.4 1.3 0.4 1.0 -0.9 1.1 -0.0 -0.0 0.1 0.3
Number of full brothers 1.9 2.4 8.8 1.0 0.2 -0.2 0.3 3.0 1.3 1.7 2.2
Worry too long after embarrassment 0.9 1.5 5.1 -0.3 -0.6 0.7 -1.9 -2.3 -0.5 -0.5 -1.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.0 1.8 -0.9 0.6 -1.3 0.4 -1.2 -1.2 -1.2 0.6
Wheeze or whistling in the chest in last year 1.3 2.2 9.2 -0.0 -0.1 -0.1 -1.7 -3.0 0.3 -1.1 -2.1
Number of children fathered 2.1 2.3 9.6 0.2 0.9 -0.1 -1.9 1.3 3.1 1.6 0.7
Reason for reducing amount of alcohol drunk: Health precaution 1.1 1.3 3.8 -0.4 -1.2 0.4 0.9 -0.6 -1.9 -1.6 -0.9
Age at first live birth 2.1 3.8 8.0 -1.5 -0.4 -2.6 2.8 1.9 -1.3 -0.0 2.8
Pulse wave peak to peak time 0.7 0.8 2.2 -0.7 0.1 -0.2 1.1 -0.5 -1.5 -1.3 0.9
Health satisfaction 0.3 0.4 0.9 0.8 0.2 0.5 -0.3 -0.8 1.0 0.6 -0.8
Shortness of breath walking on level ground 0.8 1.0 3.0 -0.5 -1.0 0.2 -1.0 -1.2 1.7 0.6 -0.8
Qualifications: College or University degree 0.6 1.8 6.8 -1.9 -0.6 -2.6 0.6 0.8 0.1 -0.3 1.6
Eye problems/disorders: None of the above 1.0 1.2 2.2 -0.6 -0.9 -1.1 -1.1 -1.5 -1.3 -0.9 -1.1
Mouth/teeth dental problems: Loose teeth 1.3 1.5 4.3 1.3 2.1 -1.0 -0.1 1.3 0.7 0.5 1.7
Emphysema/chronic bronchitis 0.7 0.8 1.7 -0.1 0.2 0.6 -0.7 -1.0 1.3 1.2 -1.3
Medication for pain relief, constipation, heartburn 1.8 3.1 9.7 -0.7 -0.5 -0.6 3.1 0.6 -2.8 -1.6 1.8
Neck or shoulder pain in last month 1.7 2.4 6.8 1.2 1.5 -0.1 -2.6 -1.5 1.3 1.3 -1.6
Medication: Blood pressure 0.7 1.2 5.0 -0.2 -0.1 -0.4 -0.4 0.4 2.2 1.9 0.5
Angina (self-reported) 0.9 1.1 2.7 1.2 0.0 0.1 -1.0 -0.4 1.5 1.6 -1.2
Migraine (self-reported) 2.7 3.3 6.4 1.9 2.4 1.9 -2.5 -0.9 0.5 -0.2 -2.5
Medication: Ibuprofen 0.4 0.4 1.6 0.0 0.7 -0.0 -1.0 -0.3 -0.3 -1.3 0.0
Medication: Allopurinol 4.9 6.5 16.7 3.1 3.0 1.3 -0.9 1.1 3.6 4.1 -0.3
Medication: Omeprazole 0.3 0.4 1.7 0.3 -0.6 1.3 -0.1 -0.3 0.0 -0.6 -0.5
Medication: Seretide 50 evohaler 0.3 0.4 1.5 -0.6 0.2 -0.3 -1.2 0.5 0.7 0.4 0.2
Mean time to correctly identify matches 1.7 3.2 9.4 -1.1 -1.0 -1.1 2.3 -1.7 -3.1 -2.1 -0.4
Heart disease (mother) 0.4 0.5 0.8 -0.1 -0.9 -0.8 0.3 0.8 0.9 0.5 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 0.8 0.6 -0.9 0.8 0.4 0.7 0.3 -0.0 0.1
Whole body fat mass 1.3 5.3 10.6 3.3 1.6 -0.3 -1.8 2.6 3.2 2.9 0.4
Leg fat mass (right) 1.7 6.6 15.8 3.3 1.3 0.2 -2.0 2.7 4.0 3.6 -0.0
Arm predicted mass (right) 1.3 6.6 15.8 2.5 3.2 -0.3 -1.9 1.9 3.6 4.0 -0.2
Pulse rate, automated reading 0.2 0.8 1.5 -0.9 1.0 1.2 0.4 0.5 -1.1 -1.2 0.4
Alcohol intake frequency. 0.5 1.1 4.1 0.7 1.2 -0.5 -0.9 0.9 2.0 1.1 0.2
Comparative height size at age 10 0.9 4.8 13.3 2.3 3.6 0.3 -2.6 1.3 2.4 2.1 -0.5
Number of full sisters 0.9 1.1 3.8 0.8 1.7 1.9 -0.8 -0.4 -0.6 -0.7 -0.6
Suffer from ‘nerves’ 0.5 0.8 3.4 -0.1 0.2 -0.9 -0.7 -1.8 -1.3 -0.6 0.3
Overall health rating 0.9 2.0 9.8 0.4 0.5 0.6 -1.6 0.4 3.1 1.4 0.5
Chest pain or discomfort 0.5 0.7 2.1 -1.2 -0.0 -0.4 -0.9 -1.4 0.4 -0.4 -0.8
Had major operations 0.7 0.8 3.6 -1.1 1.9 -0.2 0.2 0.8 0.3 0.1 1.1
Age at last live birth 1.7 2.4 4.9 -1.1 -0.8 -2.0 2.1 2.0 -0.5 0.1 2.2
Family relationship satisfaction 1.0 1.3 2.8 1.6 0.9 1.4 -0.8 0.6 0.6 1.7 -0.7
Leg pain on walking 1.0 1.3 3.6 0.3 -1.4 -0.3 -0.5 -0.5 1.5 1.9 -1.3
Qualifications: NVQ or HND or HNC or equivalent 0.8 1.0 5.7 0.4 0.7 2.4 0.4 0.4 0.0 0.8 -0.6
Commuting to job workplace: Car/motor vehicle 0.1 0.2 0.4 0.0 0.4 0.1 -0.6 -0.6 0.3 0.3 -0.5
Illness, injury, bereavement, stress in last 2 years 1.1 1.3 7.5 -0.0 -0.1 0.9 0.9 -0.2 -2.7 -1.0 -0.5
Medication: Aspirin 1.0 1.3 3.6 1.2 0.8 -0.6 0.2 1.2 1.7 1.9 0.3
Supplements: Vitamin C 0.8 1.0 2.6 -0.2 -0.3 0.8 1.3 0.3 -1.4 -1.6 0.7
Knee pain experienced in last month 0.7 1.1 3.7 -0.3 -0.7 -1.3 -1.9 -0.4 1.6 0.5 -0.2
Hypertension (Self-reported) 1.3 3.6 9.6 1.7 0.9 3.0 -0.4 0.5 3.1 2.3 0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.0 4.2 -1.0 0.2 0.1 0.3 -0.6 -1.4 -2.1 0.5
Illnesses of father: Heart disease 1.1 1.5 2.7 -1.4 -0.4 -1.2 1.4 0.8 1.3 1.1 1.6
Illnesses of siblings: Diabetes 0.8 1.0 1.6 0.1 0.9 -1.2 -0.9 1.3 1.1 0.9 1.0
Smoking status: Previous 2.0 3.0 9.2 2.8 1.2 0.7 -1.1 0.3 1.6 3.0 -1.2
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.0 5.1 1.5 2.3 -0.8 -1.8 -0.1 0.3 1.8 -1.2
Whole body fat-free mass 1.3 7.4 17.6 2.4 3.6 -1.0 -1.9 2.2 3.6 4.2 0.3
Leg fat-free mass (right) 0.8 4.3 9.4 2.2 3.1 -0.8 -1.3 2.1 2.3 2.7 0.8
Arm fat percentage (left) 0.5 2.0 5.2 2.3 0.7 -0.1 -0.1 2.1 1.4 1.5 1.2
Average weekly red wine intake 0.6 0.8 2.4 -1.2 -0.1 -1.1 1.6 -0.7 -1.0 0.2 0.1
Handedness (chirality/laterality): Left-handed 0.9 1.0 3.1 1.3 1.0 -0.9 -0.3 1.0 0.8 1.8 0.5
Mood swings 0.6 1.1 2.6 0.3 0.6 -0.8 -0.7 -1.2 1.5 1.6 -1.0
Loneliness, isolation 1.8 2.6 5.9 2.2 1.5 0.5 -1.4 1.0 2.0 2.4 -0.0
Long-standing illness, disability or infirmity 1.9 2.9 10.0 0.4 0.2 0.6 -2.6 -0.1 3.2 2.1 -1.1
Ever had bowel cancer screening 0.5 0.6 1.9 -0.8 0.4 -0.1 0.9 0.5 -0.6 -0.7 1.4
Diabetes diagnosed by doctor 1.8 3.0 9.7 0.5 -0.2 1.6 0.8 3.1 1.9 2.1 1.8
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 1.4 0.8 1.2 0.4 -0.0 -0.3 0.5 1.1 -0.2
Friendships satisfaction 0.4 0.5 1.2 0.6 1.0 1.0 0.1 -0.6 -1.1 -0.2 -0.5
Qualifications: nursing, teaching 0.9 1.4 4.6 -1.7 -0.2 -2.1 -0.3 -1.5 0.5 -0.6 0.9
Commuting to job workplace: Walk 0.8 0.8 2.7 -0.5 0.9 -0.8 0.3 -0.9 -1.1 -1.6 -0.1
Eye problems/disorders: Cataract 0.3 0.4 1.9 0.4 0.4 -0.6 0.1 0.4 1.4 0.6 0.2
Mouth/teeth dental problems: Mouth ulcers 1.6 2.6 6.7 -2.2 -2.2 -0.3 0.8 -1.0 -1.4 -2.6 0.7
Medication for cholesterol 1.0 1.5 4.8 0.2 1.7 -2.2 0.7 0.4 -1.8 -0.2 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 2.3 -0.4 -0.3 -1.5 -1.1 1.0 1.5 1.3 0.5
Back pain experienced in last month 0.6 0.9 2.9 -0.2 1.7 -1.4 -0.1 0.7 0.4 0.7 1.1
Mineral and other dietary supplements 0.8 1.0 3.6 0.9 -0.1 -0.8 1.6 0.6 -1.9 -0.3 0.6
Breast cancer (self-reported) 2.1 2.5 7.0 -1.4 -0.2 0.0 -2.1 -2.6 0.9 -0.9 -2.3
Asthma (self-reported) 1.0 2.0 7.9 -0.6 -0.2 0.1 -1.0 -2.8 -0.9 -1.5 -1.8
Osteoporosis (self-reported) 0.3 0.4 1.8 -0.6 -1.3 0.1 -0.2 0.1 0.7 0.3 -0.6
Osteoarthritis (self-reported) 0.6 0.7 1.6 -1.2 -1.2 -0.1 -0.5 -1.3 0.3 -1.1 0.1
Medication: Aspirin 1.0 1.2 3.1 1.0 0.8 -0.9 0.2 1.2 1.6 1.8 0.5
Medication: Gliclazide 0.9 1.0 2.6 0.3 0.8 0.3 0.1 1.3 1.1 1.6 1.2
Illnesses of father: None of the above (group 1) 3.2 3.9 10.5 0.8 0.2 2.7 -2.1 -2.2 -0.5 -1.7 -3.2
Smoking status: Current 1.7 2.7 6.3 2.5 1.9 2.2 -1.2 1.4 1.8 0.9 0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 2.0 5.5 0.8 1.5 1.9 -2.3 -0.3 0.1 -0.9 -1.8
Whole body water mass 1.3 7.5 18.1 2.5 3.6 -0.9 -1.8 2.2 3.7 4.3 0.3
Leg predicted mass (right) 0.8 4.4 9.5 2.2 3.1 -0.8 -1.2 2.2 2.3 2.8 0.8
Arm fat mass (left) 1.0 3.9 8.5 2.9 1.6 -0.3 -1.1 2.3 2.6 2.6 0.8
Number of self-reported non-cancer illnesses 1.7 2.9 5.8 0.9 1.6 1.6 -2.4 -1.1 2.4 1.3 -1.6
Average weekly champagne plus white wine intake 1.3 1.7 3.3 -0.8 -1.4 1.1 0.3 -1.7 -1.4 -1.8 -1.2
Miserableness 0.7 1.2 4.2 -0.3 0.0 0.2 -1.4 -1.3 2.1 1.0 -0.9
Guilty feelings 1.3 1.9 4.3 0.4 -0.4 -0.6 -2.0 -2.0 1.0 1.1 -2.1
Wears glasses or contact lenses 0.8 1.0 3.6 0.4 0.0 0.5 0.2 0.9 1.6 1.9 -0.7
Ever taken oral contraceptive pill 0.3 0.3 1.8 -1.4 -0.4 -0.5 -0.3 -0.2 -0.0 0.1 -0.3
Hearing aid user 0.5 0.6 3.3 -0.8 -0.7 -1.8 -0.1 -0.2 -0.1 -0.1 0.1
Mother’s age at death 2.4 3.1 9.5 -3.1 -2.5 -1.0 1.1 -1.7 -0.6 -1.7 -0.8
Financial situation satisfaction 0.7 0.8 2.7 1.5 -0.1 0.4 0.5 1.6 0.5 0.4 1.1
Tinnitus: Yes, now most or all of the time 0.6 0.7 2.0 -1.4 -1.4 0.7 -0.6 -0.3 1.0 -0.1 0.1
Commuting to job workplace: Public transport 0.8 1.0 1.9 -1.4 -0.5 -0.2 1.3 1.3 -1.0 -0.3 1.1
Eye problems/disorders: Glaucoma 4.4 5.2 15.8 1.7 2.5 2.0 -0.9 0.7 4.0 3.2 -1.1
Medication: Blood pressure 0.9 1.7 11.2 0.8 -0.1 3.3 -0.2 -0.5 1.3 0.1 -0.2
Pain type(s) experienced in last month: Hip pain 2.4 3.0 11.3 1.3 0.2 -0.3 -1.8 0.4 3.4 2.7 -0.1
Supplements: Fish oil (including cod liver oil) 0.8 1.0 3.6 0.2 0.9 1.1 -1.9 0.5 1.6 0.1 0.3
High cholesterol (Self-reported) 0.4 0.8 1.9 0.6 0.9 0.5 -0.5 0.7 1.4 1.2 -0.8
Medication: Bendroflumethiazide 1.0 1.6 9.9 0.4 -0.5 3.1 -0.1 0.3 1.2 0.6 -0.6
Medication: Paracetamol 1.7 2.7 9.1 -0.3 1.1 0.6 -2.5 -1.6 1.3 0.3 -3.0
Medication: Lisinopril 0.6 0.8 1.8 -1.1 -0.9 0.5 1.3 0.8 0.8 0.3 1.0
Medication: Atorvastatin 1.5 1.8 5.4 -0.7 0.1 -0.5 -1.6 -1.1 2.3 1.6 -1.4
Illnesses of father: High blood pressure 0.7 0.8 2.2 -0.1 -0.1 -0.7 0.1 0.3 1.3 1.4 1.5
Alcohol drinker status: Never 0.3 0.3 0.8 -0.3 0.5 -0.9 -0.6 0.2 0.8 0.6 -0.3
Ever smoked 1.4 2.4 4.7 1.9 -0.0 1.3 -1.3 -0.7 2.1 2.2 -1.6
Basal metabolic rate 1.4 7.6 17.5 2.7 3.5 -0.7 -2.0 2.3 3.7 4.2 0.2
Leg fat percentage (left) 0.9 3.2 8.4 2.4 0.4 0.1 -1.8 1.7 2.9 2.3 -0.3
Arm fat-free mass (left) 1.6 8.1 18.0 3.0 3.5 -0.7 -2.6 1.6 3.9 4.2 -0.7
Number of operations (self-reported) 0.2 0.3 1.2 -0.8 -0.4 -0.3 -0.7 -0.1 1.1 -0.1 0.1
Average weekly beer plus cider intake 0.5 0.7 2.1 1.5 -0.5 1.2 0.8 0.3 -0.8 -0.7 0.0
Irritability 0.9 1.5 5.3 -0.6 0.3 -2.3 1.2 0.1 -0.6 1.8 1.1
Risk taking 1.3 2.0 6.5 1.8 -0.3 0.7 -0.3 1.0 2.1 2.5 -0.2
Ever had prostate specific antigen (PSA) test 1.7 1.9 3.6 -0.9 -0.1 -1.4 -0.3 -1.9 1.7 1.7 -1.8
Fractured/broken bones in last 5 years 1.8 2.3 6.4 -0.4 0.1 0.4 -2.4 -2.5 0.5 -0.8 -2.2
Age started oral contraceptive pill 1.1 1.4 4.1 -1.8 0.3 -1.1 0.6 -0.3 -1.4 -2.0 0.2
Diastolic blood pressure, automated reading 0.2 0.5 2.8 0.3 -1.7 -0.5 -0.1 -0.8 -0.2 -0.7 -0.1
Ever depressed for a whole week 1.7 2.1 10.7 0.1 -0.3 0.2 -3.3 -1.1 0.5 -0.3 -2.1
Unable to work because of sickness or disability 0.4 0.6 1.7 0.8 -0.3 0.5 -0.6 0.5 1.1 1.3 -0.1
Commuting to job workplace: Cycle 1.8 2.2 6.0 -0.6 0.9 -1.8 1.1 -2.4 -2.0 -0.8 -1.0
Myopia 1.2 1.7 4.3 -2.1 -0.7 1.0 -1.8 -0.8 1.9 0.3 -0.7
Vascular/heart problems diagnosed by doctor 1.2 3.4 9.5 -2.0 -1.0 -2.1 0.6 -1.3 -3.1 -2.4 -0.8
Cholesterol lowering medication 1.5 2.3 6.9 1.6 1.0 1.6 -1.4 0.7 2.6 1.3 -1.1
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 2.3 -0.3 -1.4 1.5 0.3 -0.2 0.5 0.1 -0.5
Pain experienced in last month 1.1 1.9 6.1 -1.0 -1.3 -0.2 2.5 0.1 -2.2 -1.3 0.0
Supplements: Calcium 1.6 1.8 4.6 -1.4 -2.1 0.4 -1.8 -0.2 1.6 0.2 -1.3
Basal cell carcinoma (self-reported) 0.1 0.2 0.5 -0.4 0.2 0.3 0.7 -0.3 0.2 -0.6 -0.1
Heart attack/myocardial infarction (self-reported) 0.8 1.0 3.6 0.2 -0.5 -1.1 -0.6 0.5 1.4 1.9 -0.1
Deep venous thrombosis (DVT) (self-reported) 1.3 1.6 3.7 -1.3 -1.3 -0.6 1.8 -1.2 -1.9 -0.4 -0.8
Heart disease (siblings) 1.0 1.3 2.5 0.8 1.5 0.5 -0.3 1.4 1.6 1.0 1.3
Alcohol drinker status: Previous 0.4 0.5 1.6 1.3 0.5 0.3 0.7 0.8 -0.5 -0.2 0.8
Pack years of smoking 0.6 0.9 3.7 1.9 1.2 0.2 0.8 0.4 -0.3 0.4 0.9
Impedance of whole body 0.4 1.8 5.8 0.5 -1.6 1.1 -0.5 -0.3 -2.1 -2.4 -0.4
Leg fat mass (left) 1.5 5.8 13.9 3.2 1.0 0.3 -2.3 2.2 3.7 3.2 -0.4
Arm predicted mass (left) 1.6 8.1 18.5 2.9 3.5 -0.8 -2.5 1.8 3.9 4.3 -0.6