TWAS hub - TTLL11

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0930	0.0340	2.1e-03	0.042	NA	0.050	NA	0.047	2.3e-04	NA	5.9e-05	NA	9.2e-05
2	GTEx	Artery Aorta	0.2060	0.0670	1.1e-03	0.116	NA	-0.001	NA	0.068	5.9e-07	NA	3.5e-01	NA	1.4e-04
3	GTEx	Cells Transformed fibroblasts	0.1780	0.0580	1.5e-03	0.003	NA	0.037	NA	0.045	1.9e-01	NA	8.1e-04	NA	2.4e-04
4	GTEx	Prostate	0.3700	0.1140	5.6e-03	-0.011	NA	0.001	NA	-0.009	8.1e-01	NA	3.0e-01	NA	6.5e-01
5	GTEx	Spleen	0.3870	0.1390	2.8e-03	0.053	NA	0.013	NA	0.046	1.7e-02	NA	1.5e-01	NA	2.5e-02
6	GTEx	Thyroid	0.1240	0.0420	1.0e-03	0.086	NA	0.057	NA	0.081	4.1e-07	NA	3.7e-05	NA	9.1e-07
7	METSIM	Adipose	0.0728	0.0239	8.2e-06	0.073	0.039	0.061	0.062	0.074	4.7e-11	1.4e-06	1.8e-09	1.2e-09	3.4e-11
8	TCGA	Breast Invasive Carcinoma	0.0376	0.0156	2.1e-04	0.038	0.018	0.026	NA	0.038	2.0e-08	9.6e-05	3.2e-06	NA	2.4e-08
9	TCGA	Liver Hepatocellular Carcinoma	0.1690	0.0710	7.8e-03	0.059	0.016	0.029	NA	0.077	9.8e-04	5.6e-02	1.6e-02	NA	1.8e-04
10	TCGA	Lung Adenocarcinoma	0.0296	0.0146	7.4e-03	0.006	0.013	0.005	NA	0.007	6.0e-02	1.0e-02	8.4e-02	NA	4.7e-02
11	TCGA	Pancreatic Adenocarcinoma	0.1830	0.0730	2.8e-03	0.029	0.056	0.060	NA	0.086	2.2e-02	2.2e-03	1.6e-03	NA	1.9e-04
12	TCGA	Prostate Adenocarcinoma	0.0843	0.0308	8.4e-06	0.057	0.051	0.062	NA	0.067	1.4e-06	4.3e-06	4.9e-07	NA	1.6e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Neck or shoulder pain in last month	5.4	7.6	13.6	-3.0	-0.5	-0.6	-2.7	-3.2	-3.7	-2.9	-3.0	-3.1	-1.9	-2.9	-3.3
Had menopause	4.0	5.0	8.2	-2.8	-0.4	-2.6	-1.0	-2.3	-2.5	-2.4	-2.5	-2.2	-2.6	-1.0	-2.9
Illnesses of siblings	4.0	5.6	8.5	2.7	-0.1	2.3	2.1	2.9	2.7	2.8	2.8	1.3	1.5	2.7	2.7
Supplements: Fish oil (including cod liver oil)	3.7	4.9	8.9	-2.5	0.2	-0.5	-2.0	-2.3	-3.0	-2.2	-2.7	-2.1	-1.6	-2.4	-2.9
Pulse wave reflection index	3.6	4.4	8.4	-2.7	1.2	-0.7	-0.8	-2.6	-2.6	-2.5	-2.6	-0.7	-1.0	-2.9	-2.6
Average weekly beer plus cider intake	3.6	5.1	16.6	2.6	-0.1	2.1	0.3	2.6	2.6	2.5	2.8	0.5	4.1	-0.8	2.3
Illnesses of mother	3.5	4.3	7.7	2.7	0.3	1.1	1.7	2.7	2.5	1.7	2.4	1.7	2.3	1.3	2.8
Bipolar Disorder (2011)	3.3	3.2	7.9	2.6	1.4	1.8	1.0	2.8	2.0	0.0	2.4	0.2	1.5	1.0	2.2
Tinnitus: Yes, but not now, but have in the past	3.3	3.5	6.5	-1.9	0.2	-1.9	-2.6	-1.4	-2.0	-1.8	-2.0	-2.1	-2.3	-1.0	-2.0
High blood pressure (siblings)	3.2	4.6	6.9	-2.3	-1.3	-2.6	-2.3	-2.4	-2.3	-2.5	-2.5	-0.6	-1.4	-2.2	-2.4
Medication: Ventolin 100micrograms inhaler	2.9	3.8	9.0	2.0	1.3	3.0	1.3	1.5	2.2	2.0	1.9	1.2	2.5	1.5	2.1
Osteoporosis (self-reported)	2.8	3.4	6.6	2.0	0.2	-1.3	0.6	2.6	2.2	1.8	2.3	1.7	2.1	1.7	2.3
Mouth/teeth dental problems: Mouth ulcers	2.7	4.4	10.8	-2.0	2.3	0.1	0.1	-2.4	-2.5	-1.6	-2.5	-3.3	-1.0	-2.2	-2.5
Schizophrenia vs Biploar Disorder	2.6	3.4	5.8	2.3	-0.5	1.5	1.4	2.1	2.4	1.4	2.0	1.8	2.3	1.1	2.3
Alcohol usually taken with meals	2.3	3.7	11.8	-1.9	-0.2	-0.5	-1.3	-2.2	-2.4	-1.1	-2.0	-2.5	-3.4	-0.5	-2.2
Heel bone mineral density (BMD) T-score, automated (right)	2.3	5.2	14.3	-2.7	-1.2	-1.0	0.4	-2.8	-2.8	-2.5	-2.7	-1.2	-0.7	-3.8	-2.7
Mouth/teeth dental problems	2.3	3.6	6.5	2.2	1.0	0.5	0.6	2.4	2.6	2.3	2.4	2.0	1.8	1.2	2.0
Eye problems/disorders: Glaucoma	2.3	2.7	6.6	1.9	-0.8	1.4	1.5	1.7	1.8	1.4	1.7	2.6	2.0	-0.4	1.7
Ever had hysterectomy (womb removed)	2.1	2.4	6.9	1.6	1.9	1.0	2.0	1.3	1.3	1.2	1.4	1.5	2.6	0.6	1.3
Mineral and other dietary supplements	2.1	2.8	5.9	1.8	-1.1	0.4	1.0	1.4	2.3	1.8	2.1	0.8	1.1	2.2	2.4
Ovarian Cancer	1.9	2.6	4.8	2.0	0.2	1.2	0.0	1.7	2.0	1.5	1.7	2.2	1.5	1.7	1.8
High blood pressure (mother)	1.9	2.6	4.8	-1.7	0.3	0.2	-1.6	-2.0	-2.0	-2.0	-1.8	-0.6	-1.4	-2.0	-2.2
Age started oral contraceptive pill	1.8	2.2	6.2	-1.4	0.1	-2.5	-1.4	-0.9	-1.7	-1.0	-1.4	-1.4	-1.9	-0.8	-1.9
HDL Cholesterol	1.7	2.9	5.6	-2.3	-2.1	-1.5	-1.0	-1.2	-1.6	-1.9	-2.0	-1.4	-2.4	-0.5	-1.7
Chronotype (morning person)	1.7	3.9	8.9	-2.4	-0.9	-1.2	-3.0	-2.4	-2.3	-0.7	-1.7	-2.7	-1.5	-0.6	-2.2
Osteoarthritis (self-reported)	1.7	2.2	4.4	-1.2	-1.9	-1.3	-2.1	-1.0	-1.7	-1.1	-1.0	-1.0	-1.6	-1.6	-1.8
Alzheimer’s Disease (in father)	1.6	1.7	3.6	-1.5	-0.5	0.9	0.1	-1.9	-1.4	-1.8	-1.6	-0.4	-1.8	-0.1	-1.6
Reaction Time	1.6	3.0	7.4	1.4	2.7	0.5	2.5	2.2	1.7	1.6	1.9	0.2	1.7	0.5	1.7
Schizophrenia (2014)	1.6	3.5	6.7	2.6	0.3	2.4	0.8	1.9	2.4	1.3	1.9	2.3	1.8	1.0	2.1
Average weekly spirits intake	1.6	2.0	3.8	1.5	-0.1	1.7	1.4	1.5	1.6	0.6	1.4	0.8	1.5	2.0	1.8
Tense / ‘highly strung’	1.6	2.6	6.1	2.0	-0.6	1.2	0.5	2.5	1.5	1.3	1.3	1.5	2.4	-1.5	1.8
Medication: Allopurinol	1.6	2.2	5.3	2.3	0.4	0.4	0.6	2.0	1.9	1.7	1.8	-0.1	1.0	0.8	2.1
Illnesses of father: High blood pressure	1.6	2.0	7.3	1.3	0.5	2.2	1.2	1.1	1.0	0.7	0.7	2.7	1.8	-1.3	0.5
Irritability	1.6	2.7	10.3	1.8	-0.9	2.3	-1.0	1.8	0.6	0.4	0.6	-0.1	2.7	-3.2	1.0
Blood Platelet Count	1.5	17.1	29.9	4.6	1.1	3.6	5.5	3.8	4.7	4.2	4.4	4.6	4.3	2.1	4.7
Eye problems/disorders: Diabetes related eye disease	1.5	1.7	5.7	-1.1	-1.6	-2.4	-1.9	-0.5	-1.1	-0.9	-0.9	-1.0	-1.2	0.2	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.4	8.4	-2.4	-0.7	-0.6	-0.0	-2.3	-2.3	-2.1	-2.1	-0.0	-0.6	-2.9	-2.4
Pulse rate	1.5	2.5	4.7	1.9	-0.9	-0.5	1.4	1.8	1.9	2.2	2.0	-0.4	0.1	2.0	1.9
Glaucoma (self-reported)	1.5	1.8	3.6	1.7	-0.1	1.3	1.1	1.4	1.2	1.3	1.4	1.9	1.8	-0.9	1.0
Average weekly red wine intake	1.5	2.2	4.3	-2.0	0.0	-0.8	-0.6	-1.7	-1.9	-1.7	-1.7	-1.1	-2.1	-0.5	-1.8
Financial situation satisfaction	1.5	1.9	6.4	-0.9	-1.4	-1.4	-2.5	-1.1	-1.2	-1.5	-1.4	-0.8	-0.3	-1.7	-1.0
Hearing difficulty/problems: Yes	1.4	2.1	5.1	-1.4	-0.1	0.7	-1.4	-1.3	-1.4	-2.2	-1.9	-0.5	-1.2	-1.8	-1.9
Medication: Co-codamol	1.4	1.6	4.4	0.9	2.1	1.7	1.1	1.6	1.0	0.6	0.9	0.8	1.7	0.8	1.2
Chronic bronchitis/emphysema (father)	1.4	1.6	3.4	1.2	-0.2	-0.3	0.1	1.8	1.5	1.0	1.4	1.9	1.5	1.5	1.3
Pulse wave Arterial Stiffness index	1.4	1.6	8.4	0.4	2.9	0.9	1.3	-0.0	-0.1	-0.2	0.0	0.5	1.4	-2.3	-0.4
Chronic bronchitis/emphysema (mother)	1.4	1.7	4.4	1.3	-1.3	0.3	1.2	2.1	1.4	1.3	1.5	0.8	0.9	1.0	1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	6.6	1.3	2.6	1.3	0.9	0.6	0.9	0.8	0.7	0.3	2.0	-1.3	0.5
Ever depressed for a whole week	1.4	1.8	4.3	-1.2	-0.8	-2.0	-2.1	-0.6	-1.4	-1.6	-1.4	-1.4	-1.1	-0.5	-0.9
Schizophrenia (2018)	1.3	2.8	6.1	2.4	0.3	1.6	0.8	1.7	2.0	1.2	1.4	2.5	1.9	0.1	2.0
Rheumatoid Arthritis	1.3	1.8	5.3	-2.1	-1.6	-1.2	-1.7	-0.5	-1.0	-1.1	-0.8	0.9	-2.3	0.4	-1.2
Medication for hormone replacement therapy	1.3	1.5	3.6	-1.2	0.4	-0.2	-0.9	-1.9	-1.7	-1.5	-1.5	-0.3	-0.7	-1.3	-1.5
Mouth/teeth dental problems: Dentures	1.3	2.1	3.9	-2.0	-1.8	-0.9	-0.1	-1.9	-1.9	-1.7	-1.5	-0.5	-1.3	-0.7	-1.6
Hypothyroidism/myxoedema (self-reported)	1.3	2.5	4.0	-1.7	-0.2	-2.0	-1.7	-1.8	-2.0	-1.8	-1.8	-0.6	-1.1	-1.4	-1.7
Pulse wave peak to peak time	1.3	1.5	7.4	-0.3	-2.7	-0.8	-1.3	0.1	0.2	0.3	0.0	-0.4	-1.4	2.4	0.5
Qualifications: nursing, teaching	1.3	2.1	8.2	-1.4	0.3	-0.1	-1.5	-1.1	-1.4	-0.9	-1.3	-2.1	-2.9	-0.0	-1.4
Medication: Bendroflumethiazide	1.3	1.9	5.7	-1.3	1.7	-0.8	-0.2	-1.2	-0.9	-1.9	-1.5	1.5	0.5	-2.4	-1.3
Neuroticism (Nagel 2018)	1.2	2.8	10.2	-1.3	-0.2	1.2	-1.5	-1.1	-1.9	-1.8	-2.0	-1.7	-0.6	-3.2	-1.6
Ulcerative Colitis	1.2	1.8	8.9	1.3	3.0	0.5	0.7	0.7	1.2	1.6	1.6	0.6	1.0	0.7	1.0
Hypothyroidism (self reported)	1.2	2.7	4.7	-2.2	-0.6	-1.9	-1.8	-2.0	-2.0	-2.0	-1.8	-0.4	-1.5	-0.6	-1.7
Medication: Lansoprazole	1.2	1.3	2.9	-1.5	-0.6	1.2	0.3	-0.9	-1.3	-1.7	-1.5	-0.5	-1.3	-0.5	-1.3
Ever highly irritable/argumentative for 2 days	1.2	1.4	4.5	1.2	0.7	0.7	0.9	1.0	1.6	0.7	0.9	1.4	2.1	0.0	1.6
Gout (self-reported)	1.2	1.7	3.5	1.9	0.5	-0.6	0.6	1.7	1.6	1.6	1.6	-0.3	0.6	1.2	1.7
Supplements: Vitamin C	1.2	1.4	5.1	-0.3	0.5	-0.6	0.8	-1.0	-1.1	-0.7	-1.4	-2.2	-0.5	-1.8	-1.5
Loneliness, isolation	1.2	1.6	3.1	-1.5	-0.0	-1.0	-1.8	-1.2	-1.4	-1.5	-1.5	-1.6	-1.3	-0.2	-1.0
Depressed Affect (Nagel 2018)	1.1	2.4	3.8	-1.5	-0.0	0.3	-1.9	-1.3	-1.9	-1.2	-1.8	-1.8	-1.6	-1.9	-1.9
Hand grip strength (left)	1.1	2.9	7.6	1.6	-2.5	0.7	1.2	1.0	1.8	1.7	1.7	2.8	0.2	2.0	1.6
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	2.9	-1.7	0.6	0.6	-0.9	-1.6	-1.5	-1.4	-1.4	-0.0	-0.3	-1.3	-1.6
Blood clot in the leg (DVT)	1.1	1.4	3.4	1.3	1.4	0.2	-0.1	1.2	0.9	1.1	1.3	1.6	1.8	-0.9	1.1
Mean time to correctly identify matches	1.1	2.0	4.5	1.1	2.1	-0.1	1.6	2.1	1.4	1.4	1.8	0.4	1.8	0.1	1.2
Commuting to job workplace: Walk	1.1	1.2	2.9	-1.1	-1.7	-1.1	-1.1	-1.3	-1.4	-0.9	-1.1	-1.0	-0.7	-0.6	-0.9
Illnesses of father: None of the above (group 1)	1.1	1.4	5.1	0.1	0.4	-1.4	-1.0	-0.1	0.2	0.7	0.6	-2.0	-1.7	2.3	0.7
Tinnitus: Yes, now most or all of the time	1.1	1.3	7.3	-0.6	2.7	-0.7	-1.7	-0.8	-0.8	0.8	-0.3	-1.3	-0.6	0.2	-0.9
Alcohol drinker status: Never	1.1	1.3	4.7	1.1	0.1	-0.8	-0.7	0.9	1.1	1.8	1.3	0.1	0.3	2.2	1.4
Fractured/broken bones in last 5 years	1.1	1.4	4.3	0.7	0.5	2.1	1.6	0.5	1.4	0.7	0.9	1.4	1.2	0.8	1.3
Pain experienced in last month	1.1	1.8	4.9	0.8	-2.0	-1.0	0.8	1.3	1.4	1.9	1.2	0.7	-0.4	2.2	1.2
Major Depression (MDD)	1.0	1.2	2.5	-1.4	-0.3	-0.4	-0.3	-1.5	-1.4	-1.0	-1.6	-1.4	-0.7	-1.0	-1.3
Pack years adult smoking proportion	1.0	1.5	2.6	-1.5	0.4	-1.3	-0.5	-1.3	-1.3	-1.4	-1.3	-1.1	-1.5	-0.6	-1.6
Hand grip strength (right)	1.0	2.8	8.0	1.6	-2.4	1.0	1.3	0.5	1.5	1.9	1.5	2.8	-0.2	2.0	1.4
Supplements: Glucosamine	1.0	1.3	3.4	-1.3	-0.4	0.9	-1.2	-0.8	-1.5	-0.9	-1.1	-0.1	-1.4	-1.1	-1.8
Medication: Levothyroxine sodium	1.0	1.7	3.0	-1.5	-0.2	-1.7	-0.9	-1.6	-1.7	-1.1	-1.6	-0.7	-0.8	-1.2	-1.6
Birth weight of first child	1.0	1.8	3.8	1.7	0.7	1.5	1.4	1.4	1.2	1.5	1.4	0.6	1.9	-1.1	1.0
Migraine (self-reported)	1.0	1.2	2.7	1.4	0.2	0.2	-0.5	1.6	1.1	0.2	1.1	1.5	1.5	0.8	1.4
Commuting to job workplace: Car/motor vehicle	1.0	1.2	2.3	1.2	-1.4	1.3	1.0	0.7	1.1	0.1	0.6	1.5	1.5	-0.4	1.0
Wears glasses or contact lenses	1.0	1.1	5.8	-1.0	-0.7	0.1	0.4	-1.0	-1.2	-0.8	-0.9	0.4	0.1	-2.4	-1.4
Type 2 Diabetes (T2D) (2012)	0.9	1.0	2.5	1.2	0.8	0.2	0.2	1.6	1.0	1.3	1.3	0.4	0.8	1.4	0.9
Allergy or Eczema	0.9	2.4	10.1	-1.8	3.2	-0.5	-1.0	-1.1	-1.6	-1.4	-1.5	-1.3	-0.6	-1.4	-1.6
Townsend deprivation index at recruitment	0.9	1.3	2.4	1.4	1.2	0.3	0.5	1.2	0.9	1.5	1.2	0.8	1.3	1.3	1.1
Medication: Atenolol	0.9	1.2	2.6	-1.1	-1.1	-0.0	-1.6	-0.8	-0.9	-1.3	-1.1	-0.2	-1.4	-0.8	-1.3
Fluid intelligence score	0.9	1.8	5.2	-1.6	0.4	0.1	-1.2	-0.4	-1.6	-1.4	-1.4	-0.9	-2.3	-1.4	-1.8
Depression (self-reported)	0.9	1.0	2.5	1.0	0.1	0.8	-1.0	1.6	0.9	1.2	1.4	0.2	-0.0	1.2	1.2
Headache pain in last month	0.9	1.6	5.4	-1.0	-0.3	-0.4	-1.2	-1.1	-1.3	-2.3	-1.6	-0.6	-0.3	-1.9	-1.0
Medication for pain relief, constipation, heartburn	0.9	1.5	5.0	-1.7	-0.2	-0.5	-0.5	-1.2	-1.2	-1.3	-1.3	-1.0	-2.2	0.5	-1.4
Heart disease (mother)	0.9	1.1	2.6	-1.4	-0.7	0.4	-1.0	-1.3	-1.3	-1.1	-1.0	0.1	-0.7	-1.0	-1.6
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	8.2	-0.6	-2.9	-1.1	0.7	-0.5	-0.6	-0.2	-0.5	-0.9	-0.2	-0.3	-0.6
Knee pain experienced in last month	0.9	1.5	5.8	0.2	0.9	2.4	2.3	-0.3	0.2	0.2	0.4	0.1	1.1	-2.0	-0.3
Illnesses of siblings: Diabetes	0.9	1.1	3.9	-0.7	0.4	-0.4	-0.0	-1.4	-1.2	-0.7	-1.2	-0.8	-0.7	-2.0	-1.3
Back pain experienced in last month	0.9	1.3	2.9	-1.2	0.2	0.2	-1.7	-1.6	-1.5	-1.1	-0.9	-0.6	0.2	-1.5	-1.2
Miserableness	0.9	1.5	7.3	-0.3	1.1	0.9	-1.7	-0.3	-1.0	-0.2	-0.4	-2.7	-0.8	-1.6	-1.0
Commuting to job workplace: Cycle	0.9	1.1	2.5	-1.1	1.4	-0.9	-0.9	-1.1	-1.2	-0.0	-0.6	-1.2	-1.6	0.5	-1.2
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	2.1	1.2	1.3	0.0	-0.1	1.1	0.8	1.0	1.2	1.5	1.5	-0.9	1.0
Heart disease (siblings)	0.9	1.1	3.8	-1.5	0.5	0.2	-1.9	-1.1	-0.8	-1.4	-0.8	-0.4	-0.3	-1.2	-0.9
Alcohol drinker status: Previous	0.9	1.1	3.8	0.3	1.1	0.8	1.9	1.2	0.8	0.0	0.5	1.9	0.9	-0.3	0.6
LDL Cholesterol	0.8	1.3	2.5	1.6	-0.0	1.5	0.8	1.2	1.4	1.4	1.4	-0.6	1.1	-0.0	1.2
Lung FEV1/FVC ratio	0.8	4.3	8.5	2.8	0.2	1.6	0.9	2.5	2.4	2.9	2.7	0.1	1.2	2.0	2.5
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	4.4	-1.0	0.0	-2.1	-1.8	-0.8	-0.8	-0.7	-0.6	-0.7	-1.0	-0.4	-0.7
Medication: Metformin	0.8	1.1	1.7	-0.9	0.2	0.2	-1.0	-1.1	-1.3	-1.2	-1.3	-1.1	-0.9	-1.0	-1.3
Serious illness, injury or assault to yourself	0.8	1.0	4.1	-0.3	1.4	-0.2	-1.6	-0.8	-0.9	0.9	-0.4	-2.0	-0.0	-0.7	-0.5
Pain all over the body in last month	0.8	0.9	1.7	1.0	0.4	-0.4	0.1	1.2	1.3	0.6	1.0	1.1	1.0	1.0	1.3
Happiness	0.8	1.0	4.6	-0.2	-0.7	-1.4	-2.1	0.6	-0.9	-1.0	-1.0	-0.5	-0.2	-1.1	-0.6
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	1.9	-0.7	-1.1	-1.0	-1.4	-1.1	-1.3	-0.7	-1.1	-1.3	-1.4	0.3	-0.6
Comparative body size at age 10	0.8	2.1	7.3	0.9	-0.2	0.5	0.4	1.5	1.5	1.7	2.0	1.6	0.9	2.7	1.6
Health satisfaction	0.8	1.0	3.2	1.0	0.5	-0.4	-0.5	1.1	1.0	0.7	1.0	1.2	1.8	-0.6	1.3
Number of self-reported non-cancer illnesses	0.8	1.3	5.2	-1.2	-0.5	-1.2	-2.3	-0.2	-0.8	-1.1	-0.5	0.6	-0.5	-2.0	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.0	-1.0	1.4	-0.9	-0.3	-1.0	-1.4	-0.8	-1.2	-0.3	-1.0	-0.6	-1.2
Pack years of smoking	0.8	1.2	2.4	-1.3	0.7	-1.1	-0.8	-1.1	-1.1	-1.2	-1.0	-0.8	-1.5	-0.5	-1.5
Bipolar Disorder or Schizophrenia	0.7	1.8	3.9	2.0	0.8	1.3	0.4	1.4	1.6	0.8	1.2	1.9	1.0	0.5	1.8
Respiratory disease	0.7	1.6	3.4	-1.8	1.7	-0.7	1.1	-1.5	-1.3	-1.4	-1.1	0.1	-0.2	-1.6	-1.1
Lung FVC	0.7	3.7	6.2	-1.8	-0.5	-1.9	-2.2	-2.5	-2.4	-1.4	-2.1	-1.2	-1.6	-2.4	-2.1
Neuroticism	0.7	1.8	9.1	-0.3	1.0	1.8	-0.9	-0.2	-1.2	-1.1	-1.2	-1.3	0.5	-3.0	-0.8
Number of treatments/medications taken	0.7	1.2	4.8	0.9	1.1	1.1	-0.0	0.8	0.4	0.5	0.5	1.0	2.2	-2.0	0.1
Frequency of depressed mood in last 2 weeks	0.7	0.9	5.2	-0.1	-0.7	-1.3	-2.3	0.0	-0.4	-0.3	-0.3	-1.7	-0.6	0.3	0.1
Systolic blood pressure, automated reading	0.7	2.0	10.4	-1.4	-1.9	1.7	-0.9	-1.1	-0.4	-1.3	-0.6	3.2	-0.2	-0.4	-0.7
Severe depression (siblings)	0.7	0.8	4.6	0.9	-0.5	2.1	0.7	0.4	0.8	1.2	0.5	-0.1	0.7	-0.6	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	2.9	0.8	-1.7	-0.6	-1.3	0.8	0.9	0.6	0.9	0.6	-0.0	1.2	1.2
Multivitamins +/- minerals	0.7	0.9	5.9	-0.3	0.1	-1.6	-0.3	-0.5	-0.7	0.3	-0.5	-2.4	-1.0	0.3	-0.2
Nervous feelings	0.7	1.3	4.6	1.4	0.2	1.4	0.1	1.3	0.9	0.6	0.8	1.0	2.1	-0.7	1.3
Hearing difficulty/problems with background noise	0.7	1.2	3.3	-0.9	-0.1	0.2	-1.5	-1.0	-1.1	-1.8	-1.4	-0.2	-0.7	-1.3	-1.2
Impedance of arm (right)	0.7	3.2	9.3	2.0	2.2	0.9	3.1	2.0	1.6	1.7	1.3	0.2	2.2	0.2	1.9
Medication: Cholesterol lowering	0.7	1.1	3.0	0.8	0.1	-0.9	-1.7	1.3	0.7	1.6	1.4	-0.8	0.7	-0.4	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	5.0	0.1	-0.3	0.4	-1.6	-0.1	-0.6	-0.4	-0.5	-1.8	0.6	-2.2	-0.4
Hair/balding pattern: Pattern 4	0.7	1.7	6.8	1.2	0.2	2.6	-0.0	1.1	0.9	1.4	1.4	1.1	1.5	-0.3	1.3
Medication: Paracetamol	0.7	1.2	3.1	1.3	0.5	1.6	1.6	1.0	0.8	0.8	0.7	-0.0	1.8	-0.7	1.0
Eye problems/disorders: None of the above	0.7	0.8	6.6	0.0	2.6	0.6	1.0	-0.7	-0.1	-0.5	-0.5	-0.5	-0.4	0.4	-0.1
Emphysema/chronic bronchitis	0.7	0.8	2.4	-0.9	-0.4	0.6	-0.2	-1.4	-0.5	-1.4	-0.7	0.7	-1.5	-0.5	-0.4
Number of full sisters	0.7	0.8	5.2	-0.6	-1.1	-2.3	0.1	-1.0	-0.3	-0.7	-0.7	0.1	-0.5	-0.2	-0.5
Had major operations	0.7	0.8	2.8	-0.2	-0.1	1.6	-1.4	-0.7	-0.4	-0.5	-0.3	0.3	1.1	-1.7	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	4.5	1.6	0.3	2.1	1.3	1.2	1.0	1.4	0.8	0.4	1.1	-0.3	1.3
Friendships satisfaction	0.7	0.9	1.7	-0.7	1.3	-0.1	-1.0	-0.4	-0.7	-1.0	-1.0	1.3	-0.2	-1.3	-1.0
Mother’s age at death	0.7	0.8	4.9	0.1	-2.2	-0.8	-0.5	0.6	0.7	1.0	0.5	1.4	-0.6	-0.1	-0.1
Medication: Atorvastatin	0.7	0.9	7.1	-0.5	2.7	0.9	0.4	0.3	-0.5	-0.4	-0.4	-0.9	-0.4	-0.7	-0.8
Supplements: Calcium	0.7	0.8	5.4	-0.5	0.8	-2.3	-0.6	0.1	-0.4	-0.6	-0.5	0.3	-0.5	1.0	-0.6
Basal cell carcinoma (self-reported)	0.7	0.8	2.9	-1.4	0.0	-0.1	-0.2	-1.0	-1.1	-1.1	-0.8	-0.4	-1.7	0.5	-0.8
Worry (Nagel 2018)	0.6	1.2	7.9	-0.0	-0.1	1.1	-0.7	-0.0	-0.8	-0.8	-1.1	-1.2	0.9	-2.8	-0.2
Breast Cancer	0.6	1.5	3.0	-1.1	-0.6	-1.5	-1.2	-1.0	-1.4	-1.7	-1.3	0.1	-1.6	-0.9	-1.3
Coronary Artery Disease (CAD)	0.6	0.7	1.9	-0.9	0.5	0.4	0.1	-0.9	-0.8	-1.2	-0.5	-0.6	-1.4	0.9	-0.9
Sensitivity / hurt feelings	0.6	1.0	2.2	-1.2	-0.5	0.5	-1.2	-0.8	-1.2	-1.3	-1.1	-0.5	0.1	-1.5	-1.0
Hayfever, allergic rhinitis or eczema	0.6	1.3	4.7	-1.4	2.2	-0.2	-0.8	-0.7	-1.3	-0.9	-1.0	-1.0	-0.1	-1.4	-1.1
Financial difficulties in last 2 years	0.6	0.8	2.1	-0.6	-1.4	0.1	-0.6	-0.4	-1.0	-1.1	-1.0	0.4	0.8	-1.4	-0.5
Allergy	0.6	1.3	3.7	1.4	-1.8	0.1	0.2	1.1	1.3	1.0	0.9	1.0	-0.2	1.9	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.6	0.9	3.1	-0.6	-0.0	-0.8	-1.8	-0.8	-0.8	-1.0	-0.9	-1.6	-0.6	-0.5	-0.6
Falls in the last year	0.6	0.8	2.4	-0.8	1.2	1.4	0.6	-1.0	-0.8	0.5	-0.5	-1.5	0.3	-0.5	-0.9
Prospective memory result	0.6	0.8	4.0	0.9	-0.2	0.8	1.0	0.1	0.7	0.7	0.9	-0.0	2.0	-0.2	1.0
Length of working week for main job	0.6	0.7	1.7	0.7	0.4	0.2	0.2	0.9	1.0	1.3	1.2	0.5	0.1	1.2	0.9
Breastfed as a baby	0.6	0.7	2.4	-0.8	-0.4	-0.5	-0.4	-0.7	-0.7	-1.2	-1.2	0.0	0.4	-1.6	-1.0
Number of children fathered	0.6	0.7	2.0	-0.3	0.6	1.3	-0.7	-0.2	-0.7	-1.4	-0.9	0.7	0.2	-1.3	-0.7
Mouth/teeth dental problems: Loose teeth	0.6	0.7	4.8	-0.4	-2.2	-0.7	-0.9	-0.3	-0.6	-0.9	-0.5	0.7	-0.4	-0.4	-0.4
Chest pain or discomfort	0.6	0.9	2.9	-1.1	0.8	-0.6	-1.6	-0.8	-1.1	-1.7	-0.9	0.1	0.1	-0.6	-0.4
Medication: Aspirin	0.6	0.7	3.9	-0.3	-0.7	-0.8	-2.0	-0.2	-0.4	-0.4	-0.0	0.8	0.4	-1.5	-0.6
Average weekly champagne plus white wine intake	0.6	0.9	4.0	0.6	0.1	-0.0	2.0	0.6	0.3	0.8	0.1	-2.0	-0.7	0.6	0.5
Hearing aid user	0.6	0.7	2.7	-0.3	1.7	1.6	0.4	-0.5	-0.3	-0.2	-0.1	0.1	1.2	-0.7	-0.3
High cholesterol (Self-reported)	0.6	1.1	3.0	1.1	-0.5	-0.5	-0.9	1.6	0.9	1.7	1.7	-0.9	0.3	0.6	0.7
Risk taking	0.6	0.9	2.9	-0.1	-1.1	-1.3	-1.6	0.2	-0.1	0.9	0.6	-1.7	-1.0	-0.0	-0.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	3.8	-0.6	0.9	-1.2	-2.0	0.7	-0.3	-0.5	-0.0	1.1	-0.2	-0.4	0.0
Diastolic blood pressure, automated reading	0.6	2.0	12.0	-1.1	-3.5	0.9	-1.0	-0.9	-0.7	-1.5	-1.0	1.4	-0.8	-1.2	-0.5
Alzheimer’s Disease (including proxy)	0.5	0.8	1.7	-0.5	-1.3	0.7	0.2	-1.1	-0.8	-0.6	-1.1	0.4	-0.8	-0.8	-1.2
Body Mass Index (BMI) (2010)	0.5	0.7	2.3	-0.8	0.2	-0.0	-1.2	-0.3	-1.0	-0.3	-0.5	-1.3	-0.2	-1.5	-0.6
Mean Putamen Volume	0.5	0.5	2.0	-0.0	1.4	-0.1	0.8	-0.0	-0.2	-0.3	-0.0	1.0	0.9	-1.4	-0.3
Fasting Glucose	0.5	0.6	4.8	0.3	0.3	0.4	-2.2	0.1	-0.1	0.7	0.3	-0.3	-0.8	0.8	-0.3
Smoking Status	0.5	1.2	3.1	-1.4	-1.1	-0.2	0.0	-1.0	-1.5	-1.8	-1.2	0.2	-0.4	-1.5	-1.2
Vitamin and mineral supplements	0.5	0.7	4.7	0.1	-1.6	0.7	-0.2	0.1	0.5	-0.4	0.4	2.2	0.3	0.5	0.4
Average weekly fortified wine intake	0.5	0.6	4.9	-0.7	2.2	-0.3	-0.4	-0.6	-0.5	-0.6	-0.7	0.2	0.1	0.5	-0.2
Relative age voice broke	0.5	0.8	2.2	1.0	0.2	0.3	1.5	1.1	1.1	0.6	0.9	0.1	1.0	0.4	1.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	4.6	-0.5	-2.1	-0.7	-0.6	0.0	-0.1	-0.6	0.0	-0.8	-0.8	0.4	-0.2
Hair/balding pattern: Pattern 2	0.5	0.6	3.8	0.4	0.6	-2.0	0.8	0.2	0.2	0.1	0.3	-1.1	-0.8	0.3	0.2
Had other major operations	0.5	0.6	1.8	-0.9	-0.6	0.0	0.1	-0.9	-0.9	-1.0	-0.7	-0.3	0.4	-1.3	-0.7
Medication: Ramipril	0.5	0.6	1.9	-0.7	0.5	1.4	-0.7	-0.6	-0.0	-1.0	-0.5	0.8	-0.8	-0.4	-0.9
Neuroticism score	0.5	1.0	4.7	0.5	0.1	1.8	-1.1	0.7	-0.2	-0.4	-0.3	-1.0	1.0	-2.2	0.3
Father’s age at death	0.5	0.6	1.7	-0.9	1.3	1.2	0.9	-0.7	-0.6	-1.0	-0.8	-0.4	0.3	-0.0	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.6	0.8	-1.6	-0.1	0.3	0.5	0.4	1.2	0.7	-1.0	0.1	0.4	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	3.3	0.9	-0.5	-0.4	0.6	0.5	0.3	0.7	0.5	0.4	1.3	-1.8	0.4
Number of full brothers	0.5	0.6	2.1	0.3	-1.0	0.8	-1.3	0.4	0.6	-0.6	0.2	1.4	0.8	-0.8	0.3
Qualifications: College or University degree	0.5	1.5	9.3	0.9	3.1	-0.5	1.1	1.2	-0.0	1.4	0.2	-1.4	-1.1	-0.3	-0.0
Medication: Ibuprofen	0.5	0.6	1.6	0.7	-1.1	-1.0	0.9	0.7	0.3	0.7	0.5	0.5	0.8	-1.3	0.3
Medication: Omeprazole	0.5	0.6	1.2	-0.7	1.1	-0.9	-0.9	-0.7	-0.9	-0.7	-0.7	0.5	-0.9	0.4	-0.8
Comparative height size at age 10	0.5	2.8	6.8	1.8	1.5	1.6	0.1	1.4	1.9	1.9	2.0	2.6	1.4	1.0	1.6
Overall health rating	0.5	1.0	4.8	0.0	1.2	-0.3	-0.9	-0.2	-0.6	-0.5	-0.4	0.4	1.9	-2.2	-0.4
Family relationship satisfaction	0.5	0.6	3.3	-0.2	1.0	0.7	-0.2	0.1	-0.4	-0.7	-0.8	0.5	1.0	-1.8	-0.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.9	0.6	0.6	0.1	0.4	0.2	1.1	0.6	0.7	0.9	-0.6	1.7	0.5
Medication: Aspirin	0.5	0.7	4.0	-0.0	-0.7	-0.4	-2.0	-0.0	-0.2	-0.2	0.1	0.9	0.8	-1.3	-0.3
Illnesses of father: Heart disease	0.5	0.7	2.8	-0.5	-0.3	-0.4	-0.3	-0.8	-0.8	0.3	-0.7	-1.3	0.1	-1.7	-1.0
Ever had bowel cancer screening	0.5	0.6	3.3	-0.4	0.1	-0.0	-1.8	-0.6	-0.9	-0.1	-0.5	-0.5	-0.2	-0.8	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	2.6	0.8	0.3	0.3	-0.0	1.2	0.5	0.5	0.8	0.0	1.6	-0.6	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.3	-0.7	0.2	-1.5	-0.7	-1.3	-0.7	-0.7	-0.8	-0.4	0.4	-0.0	-0.6
Guilty feelings	0.5	0.7	2.1	-0.6	0.8	0.6	-0.8	-0.3	-0.8	-1.4	-0.9	-0.2	-0.5	-1.4	-0.7
Commuting to job workplace: Public transport	0.5	0.6	3.1	-0.9	0.9	-0.2	-0.6	-0.1	-0.6	-0.5	-0.2	-0.9	-1.8	0.6	-0.5
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.6	-1.3	-0.1	0.5	-0.7	-0.5	-0.9	-0.9	-0.8	-0.6	-0.9	-0.2	-1.0
Medication: Lisinopril	0.5	0.6	4.5	0.6	-0.1	-2.1	-0.4	0.6	0.4	0.1	0.5	0.3	0.6	0.5	0.9
Ever smoked	0.5	1.0	4.6	-0.9	-0.5	0.3	-0.1	-0.7	-1.2	-0.9	-1.0	-0.5	0.3	-2.1	-1.2
Unable to work because of sickness or disability	0.5	0.6	3.1	0.3	1.1	0.0	0.1	-0.3	0.3	-0.3	0.0	1.4	1.8	0.5	0.9
Myopia	0.5	0.7	2.2	0.5	1.1	0.8	1.2	0.6	0.5	0.0	0.5	1.1	1.5	-0.8	0.5
Depression (Nagel 2018)	0.4	0.7	2.0	-0.8	-1.0	-0.7	-1.4	-0.6	-0.8	-0.4	-0.7	-0.8	-1.0	-0.2	-0.4
Irritable Bowel Disease (IBD)	0.4	0.9	3.5	1.2	1.9	1.3	0.9	-0.0	0.8	0.7	0.6	0.5	0.8	-0.4	0.5
Ulcerative Colitis (UC)	0.4	0.8	7.2	0.7	2.7	0.5	-0.3	-0.2	0.3	0.6	0.5	-0.3	0.7	-0.4	0.1
Verbal and Numeric Reasoning (VNR)	0.4	1.0	2.6	-0.8	1.6	0.0	-0.8	0.6	-1.0	-0.6	-0.4	-1.4	-1.0	-1.5	-1.0
Age at First Birth	0.4	0.6	4.6	0.1	0.9	-1.0	-0.5	0.1	0.0	0.2	-0.2	-0.1	-0.3	-2.1	-0.3
Blood Red Count	0.4	3.8	9.5	-2.4	1.6	-1.0	-0.6	-3.1	-2.0	-3.0	-2.4	0.4	-0.8	-1.9	-1.8
Heel T-Score	0.4	3.3	17.4	-1.3	1.4	0.3	1.7	-1.8	-1.9	-1.3	-1.5	-0.4	1.2	-4.2	-1.7
BMI	0.4	2.3	5.3	-1.9	0.1	0.1	-2.3	-1.9	-2.1	-1.7	-1.4	0.0	-0.3	-1.7	-1.9
Height	0.4	7.6	16.1	4.0	0.7	2.1	0.7	3.2	3.6	3.2	3.5	2.8	2.3	1.1	3.2
Systolic Blood Pressure	0.4	2.1	18.7	-0.1	-0.9	1.2	0.2	-0.0	1.2	-0.0	0.5	4.3	0.1	1.2	0.7
Type 2 Diabetes (T2D) (2018)	0.4	0.8	3.3	-0.5	1.8	0.6	-0.8	-0.9	-0.7	-0.9	-0.7	-0.1	-0.0	-1.5	-0.8
Angina	0.4	0.5	2.4	-0.1	0.5	0.7	-1.4	0.1	0.1	0.1	0.4	0.3	-0.0	1.5	0.3
Diabetes (father)	0.4	0.5	1.5	-0.5	1.2	0.4	0.1	-0.1	-0.2	-1.0	-0.4	0.7	1.2	-1.2	-0.3
Current tobacco smoking	0.4	0.7	4.1	-0.8	-2.0	-0.8	0.3	-0.5	-0.6	-1.1	-0.7	0.6	-0.2	-0.4	-0.5
Maternal smoking around birth	0.4	0.6	2.5	0.7	-0.3	0.2	0.5	0.5	0.6	1.0	0.6	-0.5	0.9	1.6	1.1
Age when periods started (menarche)	0.4	0.9	4.9	0.8	-0.3	0.7	1.4	0.0	0.4	1.0	0.5	-0.7	1.1	-2.2	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.5	-0.2	0.8	0.6	-1.6	-0.0	-0.5	-0.2	-0.2	-1.1	-0.5	-1.4	-0.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.0	0.3	-0.9	-0.9	-1.0	0.6	0.2	0.2	0.1	-1.0	0.4	0.8	0.8
Heart attack	0.4	0.5	1.8	-0.1	1.2	-1.3	-0.2	0.2	0.3	0.6	0.4	-0.8	-0.4	1.1	0.4
Diabetes (self-reported)	0.4	0.6	2.3	0.0	1.3	-0.5	-0.4	-0.3	-0.3	-0.4	-0.3	1.1	0.9	-1.5	-0.4
Medication: Simvastatin	0.4	0.6	4.2	0.4	-0.6	-0.9	-2.1	0.4	0.2	0.8	0.7	0.0	-0.1	-0.2	-0.0
Number of live births	0.4	0.5	1.3	-1.0	-0.6	0.8	-0.0	-1.0	-0.7	-0.8	-0.8	-0.0	-0.5	1.1	-0.5
Exposure to tobacco smoke at home	0.4	0.4	2.7	-0.1	1.6	-1.2	0.0	-0.1	-0.1	-0.7	-0.1	0.2	0.4	0.1	0.1
Medication: Amlodipine	0.4	0.6	1.1	-1.1	0.7	-0.1	-0.9	-0.9	-1.0	-0.8	-0.8	0.2	-0.8	-0.1	-0.8
Worry too long after embarrassment	0.4	0.7	3.0	-0.6	0.3	1.4	0.3	-0.5	-0.8	-0.8	-1.0	-0.2	-0.6	-1.7	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.0	0.2	-0.8	0.3	-1.4	0.4	-0.2	-0.3	-0.0	-1.1	0.6	-1.0	0.2
Angina (self-reported)	0.4	0.5	2.2	-0.2	0.7	0.8	-1.5	0.1	-0.0	0.1	0.4	0.0	-0.0	1.5	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	2.5	-0.4	-1.6	1.1	-0.2	-0.8	0.1	-0.1	-0.1	-0.4	0.2	0.1	0.5
Age at last live birth	0.4	0.6	1.9	0.1	0.0	-0.6	1.4	0.0	-0.0	-0.6	-0.7	-1.4	-0.9	-0.9	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	0.9	-0.7	-0.9	-0.7	-0.6	-0.3	-0.7	-0.6	-0.7	-0.3	-0.8	-0.0	-0.9
Mood swings	0.4	0.7	2.8	0.8	-1.6	0.5	-1.7	0.9	0.3	0.6	0.7	-0.5	0.2	-0.5	0.5
Long-standing illness, disability or infirmity	0.4	0.6	3.4	-0.1	0.0	-1.4	-1.8	0.4	-0.2	0.7	0.5	-0.5	0.7	-0.6	-0.2
Diabetes diagnosed by doctor	0.4	0.6	2.4	0.2	1.6	-0.2	-0.8	0.2	-0.1	-0.1	0.1	1.1	0.7	-1.4	-0.4
Eye problems/disorders: Cataract	0.4	0.4	2.1	0.6	-1.4	-0.1	-0.1	0.8	0.4	1.0	0.6	-0.7	0.4	0.2	0.2
Smoking status: Current	0.4	0.6	3.0	-0.7	-1.7	-0.6	0.4	-0.4	-0.5	-1.1	-0.7	0.7	0.0	-0.3	-0.3
Medication: Paracetamol	0.4	0.6	1.7	1.0	0.1	0.4	1.3	0.6	0.5	1.0	0.6	0.3	1.3	-0.4	0.7
Neuroticism (2016)	0.3	0.4	3.5	-0.0	-0.8	1.9	-0.3	0.3	-0.0	-0.2	-0.1	0.2	0.2	0.3	-0.0
Primary Biliary Cirrhosis	0.3	0.5	3.3	0.4	0.7	1.8	0.5	0.2	0.5	0.1	0.1	0.6	0.2	0.4	0.5
Supplements: Zinc	0.3	0.4	2.0	0.0	-1.4	-0.3	0.2	0.1	-0.3	-0.0	-0.2	-0.2	0.3	-1.4	-0.2
Fed-up feelings	0.3	0.6	3.9	-0.1	0.1	0.5	-2.0	-0.1	-0.5	-0.8	-0.6	-0.8	-0.1	-1.2	-0.2
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	2.4	-0.1	0.8	-1.6	-0.2	-0.2	-0.4	0.2	0.1	-0.7	0.2	0.1	-0.2
Qualifications: CSEs or equivalent	0.3	0.5	2.3	-0.2	-0.7	1.3	1.5	0.2	0.5	0.0	0.5	0.4	0.3	0.3	0.2
Stomach or abdominal pain in last month	0.3	0.4	1.4	-0.2	1.1	0.5	-1.1	0.1	-0.6	-0.2	-0.2	-0.2	0.4	-1.2	0.2
Body mass index (BMI)	0.3	1.2	3.1	-1.3	-0.6	-0.2	-1.8	-1.3	-1.1	-1.5	-0.7	0.5	0.4	-1.5	-0.9
Impedance of leg (left)	0.3	1.3	5.7	0.6	1.1	0.4	2.4	1.3	1.0	0.7	0.6	0.4	0.9	1.7	1.0
Number of incorrect matches in round	0.3	0.5	1.4	1.2	0.4	-0.2	0.0	0.3	0.7	1.0	0.7	0.8	0.9	-0.1	0.8
Qualifications: None of the above	0.3	0.6	4.8	0.4	0.3	0.9	0.6	-0.0	0.2	-0.4	0.3	0.6	2.2	-0.0	0.6
Time employed in main current job	0.3	0.4	1.2	0.2	-1.0	0.5	1.1	0.3	0.4	-0.2	0.3	1.0	0.1	-0.6	-0.1
Worrier / anxious feelings	0.3	0.6	3.3	0.5	0.1	1.2	-1.1	0.1	-0.1	-0.0	-0.2	-1.1	0.1	-1.8	0.0
Hair/balding pattern: Pattern 3	0.3	0.5	1.0	-0.8	-1.0	-0.3	0.6	-0.7	-0.7	-0.8	-0.9	0.5	-0.4	-0.4	-0.8
Noisy workplace	0.3	0.4	1.6	-0.4	1.3	-0.6	-0.7	-1.0	-0.4	-0.2	-0.4	0.4	0.3	-0.5	-0.0
Impedance of arm (left)	0.3	1.4	6.6	1.0	1.8	0.4	2.6	1.2	0.8	1.0	0.5	-0.9	0.9	0.2	0.9
Loud music exposure frequency	0.3	0.3	1.7	0.4	0.2	-1.3	-0.0	0.2	0.4	0.6	0.2	-0.9	-0.1	-0.2	0.3
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	1.8	-0.3	-0.7	0.9	1.3	-0.5	0.0	-0.8	-0.5	0.5	-0.9	1.3	0.2
Leg fat percentage (right)	0.3	0.9	1.9	-1.3	0.2	0.4	-1.1	-0.8	-0.7	-1.4	-0.5	1.3	1.1	-1.3	-0.7
Exposure to tobacco smoke outside home	0.3	0.4	1.5	-0.5	0.3	-0.5	0.0	-0.8	-0.6	-0.7	-0.7	-1.2	0.7	-0.3	-0.1
Age at first live birth	0.3	0.6	1.8	0.5	1.1	0.7	0.9	0.2	0.1	0.3	-0.3	-1.3	-0.9	-0.9	-0.4
Shortness of breath walking on level ground	0.3	0.3	0.8	-0.6	-0.8	-0.9	0.4	-0.4	-0.5	-0.4	-0.3	0.1	-0.7	-0.5	-0.4
Medication: Blood pressure	0.3	0.5	1.9	0.1	1.0	-1.0	-0.6	0.5	0.0	0.1	0.1	0.5	1.1	-1.4	-0.3
Medication: Seretide 50 evohaler	0.3	0.4	1.5	-0.1	-0.0	0.8	-1.0	0.3	0.0	-0.3	0.0	-0.1	0.8	-1.2	0.0
Suffer from ‘nerves’	0.3	0.5	1.8	0.4	-0.9	0.1	-1.3	0.5	0.0	-0.0	-0.2	-0.6	0.8	-1.3	0.3
Leg pain on walking	0.3	0.3	1.7	0.0	1.3	-0.7	-0.3	-0.1	-0.4	0.4	-0.1	-0.4	-0.1	-0.8	-0.5
Hypertension (Self-reported)	0.3	0.9	3.5	-0.7	0.8	0.1	-1.7	-0.6	-0.6	-0.8	-0.8	0.7	0.0	-1.9	-0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	2.4	0.7	-0.4	1.6	0.6	0.2	0.2	0.8	0.4	0.1	1.1	-1.0	0.3
Ever taken oral contraceptive pill	0.3	0.3	2.0	0.3	-0.7	0.9	-0.5	-0.3	-0.2	-0.2	-0.1	-1.4	0.1	0.4	0.1
Number of operations (self-reported)	0.3	0.5	1.4	-0.6	-0.5	0.8	-0.5	-0.9	-0.9	-0.5	-0.4	-0.1	0.2	-1.2	-0.9
Vascular/heart problems diagnosed by doctor	0.3	0.8	4.9	0.7	-0.4	0.1	2.2	0.5	0.6	0.5	0.6	-0.5	-0.1	1.3	0.7
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.4	-0.0	1.1	-1.2	-0.2	0.2	0.3	0.7	0.4	-0.9	-0.4	1.0	0.4
Impedance of whole body	0.3	1.4	6.0	0.9	1.5	0.4	2.4	1.3	0.9	1.0	0.5	-0.5	1.0	1.0	1.0
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.4	-0.7	0.8	0.2	0.2	0.6	-0.8	-0.4	-0.7	-1.6	-1.3	-0.5	-1.1
Alzheimer’s Disease (in mother)	0.2	0.2	1.1	-0.0	-1.0	-0.7	-0.5	-0.2	-0.4	-0.1	-0.4	0.4	-0.2	-0.1	-0.5
Crohns Disease (2017)	0.2	0.4	1.7	0.8	-0.1	1.3	1.1	-0.3	0.4	-0.0	-0.1	0.5	0.5	-0.8	0.3
Crohns Disease (2012)	0.2	0.4	1.5	0.7	0.1	1.2	1.0	-0.1	0.8	0.2	0.4	0.3	0.3	0.0	0.7
HbA1C	0.2	0.2	0.4	-0.1	-0.1	-0.6	-0.6	0.3	0.1	0.4	0.4	0.6	-0.4	-0.7	-0.2
Lupus	0.2	0.2	1.0	-0.3	-0.0	0.6	-1.0	-0.3	-0.6	-0.0	-0.6	-0.1	-0.6	-0.0	-0.5
Blood Eosinophil Count	0.2	1.5	3.4	-1.6	0.7	-1.3	-0.3	-0.9	-1.6	-0.8	-1.0	-1.0	-1.9	-0.4	-1.8
Waist Hip Ratio (WHR)	0.2	0.9	4.7	0.4	1.9	0.6	0.9	0.2	-0.1	-0.0	-0.3	0.4	0.2	-2.2	-0.6
Relative age of first facial hair	0.2	0.5	2.0	0.3	-1.0	-1.0	1.0	0.2	0.1	0.1	0.0	-1.4	-0.2	-0.4	0.0
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.4	0.0	1.2	-0.7	-0.4	0.2	0.1	0.4	0.5	-0.9	0.6	-0.4	-0.0
Diabetes (mother)	0.2	0.3	0.6	0.8	0.3	-0.4	0.3	0.8	0.6	0.6	0.7	-0.1	0.1	0.4	0.5
Impedance of leg (right)	0.2	1.2	4.9	0.7	1.5	0.9	2.2	1.1	0.9	0.6	0.6	0.2	1.1	1.1	0.9
Leg fat-free mass (left)	0.2	0.9	3.5	1.0	0.6	1.9	-0.4	0.5	0.7	0.3	0.8	1.3	1.0	-1.3	0.5
Trunk fat percentage	0.2	0.7	3.8	0.0	0.4	0.9	0.2	0.4	0.3	-0.1	0.5	1.3	1.9	-1.3	0.3
Taking other prescription medications	0.2	0.4	2.1	0.2	0.8	0.0	-1.4	-0.3	-0.1	0.8	0.1	-0.4	0.5	-0.5	-0.5
High blood pressure	0.2	0.7	3.1	-0.4	0.3	0.4	-1.8	-0.5	-0.5	-0.4	-0.5	0.7	0.4	-1.7	-0.6
Leg predicted mass (left)	0.2	0.9	3.7	0.9	0.6	1.9	-0.5	0.3	0.6	0.2	0.8	1.2	0.9	-1.3	0.4
Trunk fat mass	0.2	0.9	3.1	0.0	0.6	1.2	-0.2	0.3	0.2	-0.2	0.5	1.6	1.8	-1.6	0.2
Waist circumference	0.2	0.8	3.7	-0.3	0.9	0.8	-0.5	-0.2	-0.2	-0.7	-0.0	1.4	1.1	-1.9	-0.3
Past tobacco smoking	0.2	0.3	1.3	0.4	0.4	0.1	0.0	0.3	0.8	0.5	0.4	0.8	-0.3	1.1	0.8
Arm fat percentage (right)	0.2	0.8	3.9	-0.7	0.3	0.3	-0.6	-0.5	-0.6	-1.0	-0.3	0.8	1.4	-2.0	-0.3
Alcohol intake versus 10 years previously	0.2	0.3	1.3	0.0	-0.8	-0.8	-0.8	-0.6	-0.3	0.0	0.1	-1.2	-0.0	0.1	-0.5
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.7	0.2	0.6	-0.8	-1.0	0.4	-0.5	-0.2	-0.3	-0.9	-1.3	-0.4	-0.2
Asthma	0.2	0.3	1.2	-1.1	0.1	-0.3	0.7	-0.9	-0.6	-0.6	-0.5	-0.1	0.4	-0.7	-0.3
Lung cancer (father)	0.2	0.2	0.7	0.3	-0.8	-0.3	-0.2	0.5	0.2	-0.5	-0.1	-0.0	0.5	-0.8	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	1.8	1.1	0.9	1.4	0.3	0.2	0.3	1.0	0.5	-0.4	0.3	-0.7	0.4
Arm fat mass (right)	0.2	0.9	3.7	-0.7	0.0	0.4	-1.0	-0.8	-0.6	-1.1	-0.3	1.0	1.2	-1.9	-0.4
Standing height	0.2	2.4	5.1	2.0	1.8	2.3	1.3	1.6	1.6	1.4	1.5	1.6	1.0	-0.5	1.0
Peak expiratory flow (PEF)	0.2	0.4	1.8	-0.2	1.3	1.2	0.0	-0.4	-0.0	0.2	0.0	-0.7	-0.6	0.8	-0.2
Body fat percentage	0.2	0.7	3.1	-0.5	0.6	0.7	-0.3	-0.0	-0.2	-0.6	0.1	1.2	1.8	-1.5	-0.1
Wheeze or whistling in the chest in last year	0.2	0.3	0.9	-0.2	0.1	0.7	0.2	-0.1	0.4	-0.9	0.1	0.7	0.9	-0.4	0.5
Whole body fat mass	0.2	0.9	3.3	-0.2	0.4	1.1	-0.6	0.0	0.0	-0.5	0.2	1.6	1.8	-1.7	0.1
Leg fat mass (right)	0.2	0.8	2.7	-0.5	0.4	0.8	-0.8	-0.4	-0.2	-1.0	-0.1	1.6	1.5	-1.5	-0.1
Alcohol intake frequency.	0.2	0.4	1.3	-0.6	-0.5	-0.3	-0.6	-1.1	-0.7	-0.2	-0.6	-0.4	-0.8	0.8	-0.5
Smoking status: Previous	0.2	0.3	1.3	-0.5	0.1	-0.1	-0.1	-0.4	-0.9	-0.4	-0.4	-0.7	0.1	-1.1	-0.8
Arm fat percentage (left)	0.2	0.9	3.6	-1.2	0.3	0.2	-0.7	-0.9	-1.0	-1.2	-0.7	0.3	0.8	-1.9	-0.8
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	-0.3	-0.6	-0.1	-0.8	-0.7	-0.1	-0.2	-0.2	-0.2	-0.5	0.3	-0.1
Medication for cholesterol	0.2	0.3	0.7	0.4	-0.5	-0.7	0.1	0.6	0.7	0.8	0.6	0.3	0.0	0.4	0.7
Asthma (self-reported)	0.2	0.4	1.1	-1.1	0.5	-0.6	0.5	-0.9	-0.5	-0.6	-0.4	-0.1	0.3	-0.7	-0.2
Medication: Gliclazide	0.2	0.2	1.2	0.4	-0.6	-0.2	-1.1	0.3	0.1	-0.0	0.2	0.5	0.1	-0.4	-0.2
Arm fat mass (left)	0.2	0.8	3.3	-0.9	0.1	0.6	-1.1	-0.8	-0.7	-1.1	-0.4	0.8	1.0	-1.8	-0.6
Leg fat percentage (left)	0.2	0.8	2.0	-1.3	-0.1	0.2	-1.0	-0.7	-0.7	-1.3	-0.4	1.4	0.9	-1.1	-0.6
Cholesterol lowering medication	0.2	0.3	0.9	-0.4	0.0	0.5	-0.9	-0.0	-0.5	-0.5	-0.1	0.3	-0.2	-0.7	-0.8
Leg fat mass (left)	0.2	0.8	2.4	-0.5	0.5	0.8	-0.9	-0.4	-0.2	-0.9	-0.1	1.6	1.5	-1.5	-0.2
Bipolar Disorder (2018)	0.1	0.2	0.8	0.1	0.9	0.2	-0.5	0.1	0.1	-0.1	0.1	0.0	-0.8	0.6	0.4
Cardiovascular Disease	0.1	0.4	2.6	0.0	0.6	0.0	-1.6	0.0	-0.1	-0.2	-0.2	0.3	-0.1	-1.3	-0.4
Tanning	0.1	1.2	5.2	-0.2	-2.3	1.0	-2.1	-0.7	-0.5	-0.6	-0.5	0.2	-0.8	-1.2	-0.5
Sitting height	0.1	1.0	3.0	1.7	0.3	0.8	0.3	1.0	1.1	1.1	1.2	1.2	0.5	-0.3	1.0
Forced vital capacity (FVC)	0.1	0.2	1.5	0.1	0.5	1.2	-0.4	-0.3	-0.1	0.1	-0.0	0.1	-0.0	-1.0	-0.1
Weight	0.1	0.7	2.8	-0.3	0.3	0.9	-1.0	-0.4	-0.2	-0.7	0.1	1.2	0.9	-1.7	-0.3
Trunk fat-free mass	0.1	0.7	2.1	-0.0	0.1	1.5	-1.4	-0.4	-0.1	-0.5	0.2	1.4	-0.2	-1.1	-0.4
Hip circumference	0.1	0.4	1.5	-0.3	0.2	0.9	-0.3	-0.2	0.1	-0.6	0.1	1.1	1.2	-1.1	0.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	2.9	0.5	1.2	1.7	0.3	-0.2	0.2	0.5	0.2	-0.3	0.2	-0.4	0.3
Trunk predicted mass	0.1	0.7	2.2	-0.1	0.1	1.4	-1.5	-0.5	-0.2	-0.6	0.1	1.3	-0.3	-1.2	-0.5
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.7	-0.3	-0.4	0.5	-0.7	0.3	-0.1	-0.4	-0.4	-0.0	-0.9	-0.6	-0.3
Birth weight	0.1	0.3	1.4	0.5	0.1	1.2	-0.6	0.6	0.3	0.8	0.4	-0.0	-0.6	0.2	0.4
Forced vital capacity (FVC), Best measure	0.1	0.2	1.1	0.7	0.5	0.8	-0.2	0.1	0.0	0.5	0.3	0.2	0.0	-1.1	0.0
Arm fat-free mass (right)	0.1	0.5	1.6	-0.2	0.1	1.3	-1.2	-0.3	-0.1	-0.5	-0.0	1.0	-0.3	-1.1	-0.6
Arm predicted mass (right)	0.1	0.5	1.6	-0.4	-0.4	1.2	-1.2	-0.6	-0.3	-0.7	-0.1	0.9	-0.4	-1.0	-0.7
Pulse rate, automated reading	0.1	0.3	2.5	-0.1	0.4	-0.4	0.4	-0.3	-0.5	-0.2	-0.3	-0.2	-1.6	-0.4	-0.3
Whole body fat-free mass	0.1	0.6	2.6	0.4	0.4	1.6	-1.0	-0.1	0.3	-0.2	0.4	1.3	0.3	-1.2	-0.0
Leg fat-free mass (right)	0.1	0.6	2.1	0.9	0.5	1.4	-0.4	0.4	0.6	0.3	0.7	1.2	0.7	-1.0	0.5
Breast cancer (self-reported)	0.1	0.1	0.8	-0.2	-0.3	0.1	0.9	0.1	0.1	0.0	0.1	-0.1	0.1	-0.3	-0.1
Whole body water mass	0.1	0.6	2.5	0.3	0.3	1.6	-1.0	-0.1	0.2	-0.2	0.4	1.2	0.2	-1.3	-0.1
Leg predicted mass (right)	0.1	0.6	2.1	0.8	0.4	1.4	-0.4	0.4	0.6	0.2	0.7	1.1	0.6	-1.0	0.5
Medication: Blood pressure	0.1	0.3	1.4	-0.4	-0.4	0.1	-0.6	-0.4	-0.2	-0.8	-0.4	1.2	-0.1	-0.3	-0.3
Basal metabolic rate	0.1	0.7	2.7	0.3	0.3	1.6	-0.9	-0.1	0.2	-0.3	0.4	1.4	0.5	-1.3	-0.0
Arm fat-free mass (left)	0.1	0.5	2.1	0.2	0.0	1.3	-1.2	-0.1	0.2	-0.3	0.4	1.4	0.4	-1.0	-0.1
Arm predicted mass (left)	0.1	0.7	2.5	0.1	-0.0	1.5	-1.1	-0.2	0.1	-0.5	0.3	1.6	0.5	-1.2	-0.2
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.0	0.0	0.2	0.0	0.0	0.0	0.4	-0.4	-0.2	0.0	-0.1	0.2	-0.1	-0.1	-0.0
Blood White Count	0.0	0.3	1.2	0.4	-0.4	0.0	1.1	-0.3	0.0	0.6	0.2	0.9	0.4	-0.6	0.1
Hair Pigment	0.0	1.1	1.9	0.9	0.5	-1.1	1.0	0.4	1.3	1.0	1.3	0.2	1.4	1.2	1.0

Hub : Genes

TTLL11

Models

Trait associations