TWAS hub - TTN-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Vagina	0.2710	0.1080	0.0029	0.094	NA	0.068	NA	0.113	0.0036	NA	0.012	NA	0.0015
2	ROSMAP	Brain Pre-frontal Cortex	0.0479	0.0219	0.0027	-0.002	0.005	0.007	0.005	0.002	0.7600	0.071	0.040	0.058	0.1500

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hearing difficulty/problems: Yes	7.3	11.2	21.0	1.2	4.6
Pulse rate	6.0	10.1	12.6	2.8	3.5
Pulse rate, automated reading	5.7	18.4	32.0	2.2	5.7
Alcohol drinker status: Previous	5.6	6.3	7.0	2.4	2.6
Hearing difficulty/problems with background noise	5.2	8.4	9.7	2.6	3.1
Myopia	4.3	6.3	10.3	-1.5	3.2
Prospective memory result	4.1	5.1	7.6	2.8	-1.6
Number of full sisters	3.7	4.4	8.7	-0.4	3.0
Financial situation satisfaction	3.7	4.6	8.5	0.9	2.9
Illnesses of father: None of the above (group 1)	3.5	4.3	8.1	2.9	0.7
Depression (self-reported)	3.4	4.1	5.7	-1.6	-2.4
Medication: Bendroflumethiazide	3.3	5.1	9.9	0.5	3.1
Mouth/teeth dental problems: Bleeding gums	3.2	4.2	7.7	-0.8	-2.8
Fed-up feelings	3.0	5.5	10.1	3.2	0.9
Age at First Birth	2.8	4.0	4.4	-2.1	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.8	3.3	6.1	-0.7	-2.5
Number of children fathered	2.5	2.8	4.1	1.2	2.0
Ever depressed for a whole week	2.5	3.0	3.2	-1.8	-1.7
Bipolar Disorder (2011)	2.4	2.3	4.7	2.2	-0.1
Loud music exposure frequency	2.4	2.6	3.3	-1.4	1.8
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.5	3.1	-1.8	-1.4
Medication: Ventolin 100micrograms inhaler	2.1	2.7	4.0	1.2	2.0
Medication: Amlodipine	2.0	2.8	4.9	-2.2	-0.9
Ever smoked	1.9	3.3	6.7	-2.6	-0.1
Basal cell carcinoma (self-reported)	1.9	2.2	4.0	-2.0	-0.6
Neuroticism (Nagel 2018)	1.8	4.1	8.1	2.9	0.3
Illnesses of father: Heart disease	1.8	2.5	5.1	-2.3	0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.8	1.9	3.6	0.3	1.9
Ovarian Cancer	1.7	2.3	4.6	-0.1	-2.1
Type 2 Diabetes (T2D) (2012)	1.7	2.0	2.2	-1.5	-1.3
Ever had hysterectomy (womb removed)	1.7	1.9	2.1	-1.3	-1.5
Financial difficulties in last 2 years	1.7	2.3	4.3	2.1	0.6
Alcohol intake frequency.	1.7	3.9	6.3	2.5	1.2
Commuting to job workplace: Walk	1.7	1.9	2.4	-1.2	-1.6
Falls in the last year	1.6	2.2	4.4	-2.1	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	3.8	-1.0	-1.9
Tinnitus: Yes, now most or all of the time	1.6	1.8	2.9	0.9	1.7
Age when periods started (menarche)	1.5	3.6	6.2	1.1	-2.5
Medication: Ibuprofen	1.5	1.8	2.7	0.9	-1.6
Depression (Nagel 2018)	1.4	2.1	4.1	2.0	0.3
Leg pain on walking	1.4	1.7	3.4	-0.1	1.8
Knee pain experienced in last month	1.4	2.1	4.3	0.1	2.1
Osteoporosis (self-reported)	1.4	1.7	3.3	1.8	0.1
Depressed Affect (Nagel 2018)	1.3	2.6	5.2	2.3	0.3
Major Depression (MDD)	1.3	1.6	2.3	-1.0	-1.5
Diabetes (father)	1.3	1.6	2.2	-1.5	1.0
Medication: Atenolol	1.3	1.6	2.2	-1.0	1.5
Impedance of arm (right)	1.3	6.2	7.8	2.1	2.8
Impedance of arm (left)	1.3	5.8	5.9	2.4	2.4
Birth weight of first child	1.3	2.3	2.6	-1.4	1.6
Suffer from ‘nerves’	1.3	2.0	3.4	0.8	-1.9
Commuting to job workplace: Car/motor vehicle	1.3	1.4	2.6	1.6	0.5
Long-standing illness, disability or infirmity	1.3	1.9	3.3	-0.8	1.8
Chronic bronchitis/emphysema (mother)	1.2	1.4	2.6	-1.6	0.3
Worry too long after embarrassment	1.2	2.0	3.9	2.0	-0.4
Health satisfaction	1.2	1.6	2.2	1.0	1.5
Age at last live birth	1.2	1.8	2.4	-1.1	-1.6
Unable to work because of sickness or disability	1.2	1.6	1.8	-1.2	1.3
Impedance of whole body	1.2	6.2	7.8	2.1	2.8
Alzheimer’s Disease (including proxy)	1.1	1.6	2.8	0.7	-1.7
Medication: Metformin	1.1	1.6	1.9	-1.4	-1.1
Taking other prescription medications	1.1	1.8	3.5	0.2	1.9
Number of incorrect matches in round	1.1	1.8	2.9	0.9	1.7
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	1.8	-1.4	-1.0
Neuroticism score	1.1	2.4	4.8	2.2	-0.2
Length of working week for main job	1.1	1.3	2.5	1.6	0.2
Birth weight	1.1	2.5	4.8	0.4	-2.2
Pulse wave peak to peak time	1.1	1.3	2.1	-0.7	-1.5
Qualifications: College or University degree	1.1	3.5	5.7	-1.2	-2.4
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.3	-1.5	-0.6
Risk taking	1.1	1.5	2.3	-0.9	-1.5
Age started oral contraceptive pill	1.1	1.4	2.3	-0.7	-1.5
Alzheimer’s Disease (in mother)	1.0	1.1	1.8	0.7	-1.3
Crohns Disease (2012)	1.0	1.7	3.2	-0.4	-1.8
Had other major operations	1.0	1.3	2.5	-0.3	-1.6
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	1.8	1.4	-0.8
Medication: Allopurinol	1.0	1.4	2.2	-1.5	-0.8
Loneliness, isolation	1.0	1.4	2.4	0.7	1.5
Osteoarthritis (self-reported)	1.0	1.3	1.6	1.3	1.0
Medication: Lisinopril	1.0	1.4	1.4	-1.1	-1.2
Worry (Nagel 2018)	0.9	1.9	3.2	1.8	-0.8
Breast Cancer	0.9	2.1	4.0	2.0	0.3
Neuroticism (2016)	0.9	1.3	2.3	-0.6	-1.5
Lung FEV1/FVC ratio	0.9	4.7	5.2	-2.0	-2.3
Neuroticism	0.9	2.1	4.2	2.1	-0.1
Townsend deprivation index at recruitment	0.9	1.3	1.8	0.9	1.3
Medication: Levothyroxine sodium	0.9	1.5	2.9	0.4	1.7
Trunk fat-free mass	0.9	5.4	5.8	-2.2	-2.4
Pulse wave Arterial Stiffness index	0.9	1.0	1.7	0.5	1.3
Trunk predicted mass	0.9	5.1	5.3	-2.2	-2.3
Medication: Seretide 50 evohaler	0.9	1.1	2.1	-1.4	0.1
Illnesses of father: High blood pressure	0.9	1.1	1.4	-0.9	-1.2
Heart disease (siblings)	0.9	1.1	2.0	-1.4	-0.5
Rheumatoid Arthritis	0.8	1.1	1.9	0.5	1.4
Lung FVC	0.8	4.1	4.7	1.9	2.2
Chronotype (morning person)	0.8	1.8	2.7	-1.6	0.9
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.8	1.4	0.2
Impedance of leg (right)	0.8	4.1	4.2	2.0	2.0
Diabetes (self-reported)	0.8	1.3	2.2	-1.5	-0.6
Breastfed as a baby	0.8	1.0	1.9	1.4	0.3
Wheeze or whistling in the chest in last year	0.8	1.4	2.6	-0.5	1.6
Age at first live birth	0.8	1.4	2.2	-1.5	-0.8
Medication: Blood pressure	0.8	1.5	2.9	0.2	1.7
Overall health rating	0.8	1.7	3.4	-0.2	1.8
Back pain experienced in last month	0.8	1.1	1.1	1.1	1.1
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.9	-1.4	0.3
Commuting to job workplace: Cycle	0.8	1.0	1.8	0.4	-1.3
Reaction Time	0.7	1.4	1.7	1.1	-1.3
HDL Cholesterol	0.7	1.2	2.3	0.1	1.5
Sensitivity / hurt feelings	0.7	1.2	1.5	1.2	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	2.4	0.8	1.6
High blood pressure	0.7	2.0	3.0	-1.0	1.7
Qualifications: A levels/AS levels or equivalent	0.7	1.5	2.2	1.5	0.9
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	1.3	1.2	0.9
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.6	0.2	1.6
Emphysema/chronic bronchitis	0.7	0.8	1.5	1.2	0.5
Arm predicted mass (right)	0.7	3.6	3.6	-1.9	-1.9
Had major operations	0.7	0.8	1.6	1.3	0.3
Whole body fat-free mass	0.7	4.2	4.6	-2.0	-2.1
Diabetes diagnosed by doctor	0.7	1.2	2.1	-1.4	-0.6
Whole body water mass	0.7	4.0	4.2	-2.0	-2.0
Eye problems/disorders: Glaucoma	0.7	0.8	1.1	-0.7	1.0
Medication: Blood pressure	0.7	1.4	1.4	-1.1	1.2
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.6	-0.4	-1.3
Irritability	0.7	1.2	1.4	1.0	1.2
Arm predicted mass (left)	0.7	3.8	5.0	-2.2	-1.6
Bipolar Disorder (2018)	0.6	1.0	1.2	1.1	-0.9
Schizophrenia (2018)	0.6	1.2	1.9	-1.4	-0.7
Body Mass Index (BMI) (2010)	0.6	0.8	1.5	-0.1	1.2
Fasting Glucose	0.6	0.7	1.1	-1.1	-0.6
LDL Cholesterol	0.6	0.9	0.9	1.0	-1.0
Average weekly spirits intake	0.6	0.8	0.9	-1.0	0.8
Medication: Co-codamol	0.6	0.7	1.4	-1.2	-0.2
Diabetes (mother)	0.6	0.8	1.2	-1.1	-0.6
Qualifications: CSEs or equivalent	0.6	0.8	1.3	-1.2	-0.6
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	0.9	0.9	0.7
Impedance of leg (left)	0.6	2.8	3.5	1.4	1.9
Nervous feelings	0.6	1.1	1.9	-0.6	-1.4
Hair/balding pattern: Pattern 2	0.6	0.7	1.2	0.5	-1.1
Alcohol intake versus 10 years previously	0.6	0.9	1.1	0.9	1.0
Arm fat-free mass (right)	0.6	3.3	3.5	-1.8	-1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.7	1.4	-0.3	-1.2
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.3	0.2	1.1
Mean time to correctly identify matches	0.6	1.1	1.8	0.6	-1.3
Hypertension (Self-reported)	0.6	1.6	2.8	-0.6	1.7
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.0	0.6	1.0
Miserableness	0.6	1.1	1.9	1.4	-0.5
Commuting to job workplace: Public transport	0.6	0.7	1.3	-0.3	1.1
Basal metabolic rate	0.6	3.5	3.9	-1.8	-2.0
Vascular/heart problems diagnosed by doctor	0.6	1.6	1.7	1.2	-1.3
Cholesterol lowering medication	0.6	1.0	1.9	1.4	-0.0
Pain experienced in last month	0.6	0.9	1.0	-1.0	-1.0
Supplements: Calcium	0.6	0.7	1.3	1.2	-0.2
Crohns Disease (2017)	0.5	1.2	2.2	-0.4	-1.5
Systolic Blood Pressure	0.5	2.5	3.6	-1.9	1.2
Hypothyroidism (self reported)	0.5	1.2	1.4	1.0	1.2
Hand grip strength (left)	0.5	1.3	2.5	1.6	0.3
Supplements: Zinc	0.5	0.6	1.0	-1.0	-0.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.8	-0.9	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	1.6	0.8	1.3
Mouth/teeth dental problems	0.5	0.7	1.4	0.0	1.2
Hayfever/allergic rhinitis (self-reported)	0.5	0.6	1.0	0.5	1.0
Medication: Simvastatin	0.5	0.7	1.1	1.1	0.6
Illnesses of siblings	0.5	0.8	1.5	1.2	0.2
Gout (self-reported)	0.5	0.7	0.9	-1.0	-0.6
Migraine (self-reported)	0.5	0.6	1.1	-1.1	-0.3
Chest pain or discomfort	0.5	0.7	1.4	1.2	-0.0
Leg fat-free mass (right)	0.5	2.6	2.6	-1.6	-1.6
Average weekly red wine intake	0.5	0.7	1.3	-1.1	0.4
Medication for cholesterol	0.5	0.8	1.5	0.3	-1.2
Asthma (self-reported)	0.5	0.9	1.8	-0.2	1.4
Medication: Gliclazide	0.5	0.6	0.9	-0.5	-1.0
Leg predicted mass (right)	0.5	2.5	2.7	-1.6	-1.5
Ever taken oral contraceptive pill	0.5	0.6	0.9	-0.9	-0.5
High cholesterol (Self-reported)	0.5	1.0	1.2	1.1	-0.9
Arm fat-free mass (left)	0.5	2.6	3.2	-1.8	-1.5
Schizophrenia vs Biploar Disorder	0.4	0.6	0.8	-0.9	0.6
Triglycerides	0.4	0.7	1.1	1.1	-0.4
Ulcerative Colitis	0.4	0.6	0.9	0.6	0.9
Blood Red Count	0.4	3.5	4.1	2.0	1.7
Smoking Status	0.4	1.0	1.5	-1.2	-0.7
Leg fat-free mass (left)	0.4	2.2	2.3	-1.4	-1.5
Relative age voice broke	0.4	0.6	1.2	-0.0	-1.1
High blood pressure (mother)	0.4	0.5	0.9	0.4	0.9
Leg predicted mass (left)	0.4	2.0	2.3	-1.3	-1.5
Alcohol usually taken with meals	0.4	0.6	0.8	-0.9	-0.7
Had menopause	0.4	0.5	0.5	0.6	-0.7
Hair/balding pattern: Pattern 3	0.4	0.6	1.1	-0.4	1.1
Mouth/teeth dental problems: Dentures	0.4	0.6	0.6	0.8	0.8
High blood pressure (siblings)	0.4	0.6	1.2	-1.1	-0.3
Leg fat percentage (right)	0.4	1.4	2.4	1.5	0.6
Exposure to tobacco smoke outside home	0.4	0.6	0.9	-0.5	-0.9
Family relationship satisfaction	0.4	0.5	0.7	-0.8	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	0.5	0.6	-0.7
Medication: Aspirin	0.4	0.5	0.6	-0.7	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	0.9	-1.0	1.0
Breast cancer (self-reported)	0.4	0.5	0.6	-0.8	-0.6
Hearing aid user	0.4	0.4	0.8	-0.3	0.9
Average weekly beer plus cider intake	0.4	0.5	0.8	0.9	-0.6
Bipolar Disorder or Schizophrenia	0.3	0.7	1.3	-0.4	-1.1
Alzheimer’s Disease (in father)	0.3	0.3	0.5	0.4	-0.7
Primary Biliary Cirrhosis	0.3	0.4	0.4	-0.6	-0.6
Heel T-Score	0.3	2.5	2.9	1.5	-1.7
Waist Hip Ratio (WHR)	0.3	1.2	2.1	1.5	0.4
Frequency of depressed mood in last 2 weeks	0.3	0.4	0.6	0.5	-0.8
Medication for hormone replacement therapy	0.3	0.4	0.4	-0.6	0.6
Pack years adult smoking proportion	0.3	0.5	0.9	0.3	-1.0
Trunk fat percentage	0.3	1.2	1.6	1.3	0.9
Hand grip strength (right)	0.3	0.7	1.3	1.1	0.4
Current tobacco smoking	0.3	0.4	0.9	-0.9	-0.0
Average weekly fortified wine intake	0.3	0.3	0.5	-0.7	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.7	-0.8	0.1
Supplements: Glucosamine	0.3	0.3	0.6	0.8	0.3
Allergy	0.3	0.7	1.3	1.2	0.1
Father’s age at death	0.3	0.4	0.7	0.4	0.8
Worrier / anxious feelings	0.3	0.6	1.0	0.4	-1.0
Number of live births	0.3	0.4	0.7	-0.8	-0.3
Asthma	0.3	0.6	0.9	-0.5	1.0
Medication: Lansoprazole	0.3	0.4	0.7	0.1	-0.9
Lung cancer (father)	0.3	0.4	0.8	0.9	-0.1
Exposure to tobacco smoke at home	0.3	0.4	0.7	0.1	-0.8
Peak expiratory flow (PEF)	0.3	0.6	0.9	-0.9	-0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.4	0.6	-0.7	-0.6
Glaucoma (self-reported)	0.3	0.4	0.5	-0.5	0.7
Body fat percentage	0.3	1.2	1.6	1.3	1.0
Heart disease (mother)	0.3	0.3	0.4	-0.7	-0.4
Comparative height size at age 10	0.3	1.6	3.2	-1.8	0.1
Ever had bowel cancer screening	0.3	0.4	0.6	-0.7	0.5
Mineral and other dietary supplements	0.3	0.5	0.5	-0.6	0.7
Smoking status: Current	0.3	0.5	0.9	-0.9	-0.2
Number of self-reported non-cancer illnesses	0.3	0.4	0.9	-0.2	0.9
Wears glasses or contact lenses	0.3	0.3	0.6	-0.8	0.0
Ulcerative Colitis (UC)	0.2	0.4	0.8	-0.1	0.9
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.8	0.9	0.2
Blood Platelet Count	0.2	2.4	2.5	1.6	1.5
Height	0.2	4.7	9.4	-3.1	-0.1
Allergy or Eczema	0.2	0.4	0.7	-0.5	0.8
Respiratory disease	0.2	0.4	0.9	-0.0	0.9
Tanning	0.2	2.0	2.1	-1.5	-1.4
Number of treatments/medications taken	0.2	0.4	0.7	-0.2	0.8
Systolic blood pressure, automated reading	0.2	0.6	1.1	-1.1	-0.0
Vitamin and mineral supplements	0.2	0.2	0.3	0.4	-0.5
Severe depression (siblings)	0.2	0.2	0.4	-0.7	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.3	0.6	-0.5
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.7	-0.8	0.3
Chronic bronchitis/emphysema (father)	0.2	0.2	0.4	0.6	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	0.7	0.8	0.3
Qualifications: None of the above	0.2	0.4	0.6	-0.7	0.5
Pain all over the body in last month	0.2	0.2	0.5	-0.1	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.5	0.3	-0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	1.0	-1.0	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.3	-1.1	-0.1
Pulse wave reflection index	0.2	0.2	0.4	0.3	-0.6
Headache pain in last month	0.2	0.3	0.6	0.8	0.1
Forced vital capacity (FVC), Best measure	0.2	0.6	0.8	-0.6	0.9
Eye problems/disorders: None of the above	0.2	0.3	0.3	0.5	-0.5
Angina (self-reported)	0.2	0.2	0.4	-0.7	0.0
Medication: Omeprazole	0.2	0.2	0.3	-0.5	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.6	-0.1	-0.8
Eye problems/disorders: Cataract	0.2	0.2	0.4	0.6	0.2
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.3	0.6	-0.5
Medication: Paracetamol	0.2	0.4	0.5	-0.5	0.7
Alcohol drinker status: Never	0.2	0.3	0.4	-0.3	0.7
Leg fat percentage (left)	0.2	0.8	1.6	1.2	0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.2	0.5	0.4
Fractured/broken bones in last 5 years	0.2	0.3	0.4	-0.4	0.6
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.4	0.6	0.3
Pack years of smoking	0.2	0.3	0.7	0.1	-0.8
Irritable Bowel Disease (IBD)	0.1	0.3	0.3	-0.5	-0.6
Prostate Cancer	0.1	0.2	0.4	-0.6	-0.1
Coronary Artery Disease (CAD)	0.1	0.1	0.1	0.3	-0.3
HbA1C	0.1	0.1	0.2	-0.5	-0.2
Lupus	0.1	0.2	0.4	-0.6	-0.0
Schizophrenia (2014)	0.1	0.3	0.3	-0.5	-0.5
BMI	0.1	0.5	0.8	0.9	-0.4
Cardiovascular Disease	0.1	0.4	0.6	0.3	0.8
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.3	-0.3	-0.6
Relative age of first facial hair	0.1	0.2	0.4	-0.3	-0.6
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.1	-0.2	0.3
Ever used hormone-replacement therapy (HRT)	0.1	0.2	0.2	-0.5	0.4
Angina	0.1	0.1	0.1	-0.4	-0.1
Maternal smoking around birth	0.1	0.1	0.1	-0.1	-0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.1	-0.1	-0.3
Multivitamins +/- minerals	0.1	0.1	0.1	-0.3	0.3
Sitting height	0.1	1.0	2.1	-1.4	0.0
Body mass index (BMI)	0.1	0.5	0.9	-0.1	-1.0
Trunk fat mass	0.1	0.2	0.4	0.6	0.2
Waist circumference	0.1	0.5	0.5	0.7	-0.7
Past tobacco smoking	0.1	0.2	0.3	0.6	-0.1
Forced vital capacity (FVC)	0.1	0.6	0.7	-0.8	0.7
Heart attack	0.1	0.1	0.2	0.4	0.1
Fluid intelligence score	0.1	0.3	0.3	-0.5	-0.5
Weight	0.1	0.7	1.0	-0.6	-1.0
Arm fat percentage (right)	0.1	0.5	0.7	0.8	0.5
Hip circumference	0.1	0.5	0.8	0.5	-0.9
Noisy workplace	0.1	0.2	0.2	0.3	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	0.2	-0.4
Medication: Cholesterol lowering	0.1	0.2	0.3	0.6	0.1
Illnesses of mother	0.1	0.1	0.2	0.4	-0.1
Tense / ‘highly strung’	0.1	0.2	0.4	0.6	-0.2
Medication: Paracetamol	0.1	0.1	0.1	-0.4	0.3
Number of full brothers	0.1	0.1	0.2	-0.5	-0.1
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	-0.3	0.4
Neck or shoulder pain in last month	0.1	0.2	0.4	-0.6	0.1
Illnesses of siblings: Diabetes	0.1	0.2	0.3	-0.1	-0.6
Smoking status: Previous	0.1	0.1	0.2	-0.4	0.1
Arm fat percentage (left)	0.1	0.5	0.8	0.9	0.4
Mood swings	0.1	0.3	0.5	0.7	-0.2
Friendships satisfaction	0.1	0.1	0.2	-0.4	0.1
Qualifications: nursing, teaching	0.1	0.1	0.2	-0.4	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.1	0.4	-0.4
Average weekly champagne plus white wine intake	0.1	0.1	0.1	-0.4	-0.2
Guilty feelings	0.1	0.2	0.2	0.4	-0.5
Mother’s age at death	0.1	0.1	0.1	0.1	0.3
Medication: Atorvastatin	0.1	0.2	0.3	0.5	-0.2
Number of operations (self-reported)	0.1	0.1	0.2	0.4	-0.2
Diastolic blood pressure, automated reading	0.1	0.3	0.4	-0.5	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.1	-0.3	0.1
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.1	0.3	0.4
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.1	0.2	0.3
Mean Putamen Volume	0.0	0.0	0.1	-0.3	-0.1
Blood Eosinophil Count	0.0	0.3	0.6	0.7	0.2
Blood White Count	0.0	0.2	0.3	0.6	-0.4
Hair Pigment	0.0	0.1	0.3	0.2	0.5
Stomach or abdominal pain in last month	0.0	0.0	0.0	-0.1	0.2
Medication: Ramipril	0.0	0.1	0.1	-0.3	-0.1
Time employed in main current job	0.0	0.0	0.0	-0.1	-0.2
Happiness	0.0	0.0	0.0	0.2	0.1
Arm fat mass (right)	0.0	0.1	0.2	-0.1	-0.5
Standing height	0.0	0.4	0.8	-0.9	0.1
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	0.1	-0.3
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.0	-0.0	0.0
Blood clot in the leg (DVT)	0.0	0.0	0.1	-0.1	0.2
Comparative body size at age 10	0.0	0.0	0.1	0.3	0.1
Shortness of breath walking on level ground	0.0	0.0	0.1	-0.0	-0.3
Whole body fat mass	0.0	0.1	0.1	0.4	0.2
Leg fat mass (right)	0.0	0.1	0.1	0.2	-0.2
Supplements: Vitamin C	0.0	0.0	0.0	-0.1	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.1	0.1	-0.3	-0.1
Medication: Aspirin	0.0	0.0	0.0	-0.1	-0.2
Arm fat mass (left)	0.0	0.1	0.2	-0.1	-0.4
Leg fat mass (left)	0.0	0.1	0.2	0.1	-0.4

Hub : Genes

TTN-AS1

Models

Trait associations