Hub : Genes

TWSG1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0750 0.0280 3.4e-03 0.044 0.018 0.013 0.024 0.027 3.6e-06 2.5e-03 9.6e-03 5.6e-04 2.4e-04
2 GTEx Adipose Subcutaneous 0.2410 0.0530 2.5e-07 0.159 NA 0.176 NA 0.160 5.7e-13 NA 2.5e-14 NA 4.7e-13
3 GTEx Adipose Visceral Omentum 0.2530 0.0660 1.3e-04 0.176 NA 0.165 NA 0.162 1.7e-09 NA 6.4e-09 NA 9.1e-09
4 GTEx Artery Aorta 0.3310 0.0680 1.3e-07 0.278 NA 0.245 NA 0.271 1.2e-15 NA 9.5e-14 NA 3.3e-15
5 GTEx Artery Tibial 0.3963 0.0594 1.8e-14 0.360 NA 0.367 NA 0.364 2.0e-29 NA 4.3e-30 NA 9.5e-30
6 GTEx Brain Hippocampus 0.4574 0.1292 4.8e-03 -0.010 NA -0.013 NA -0.003 6.5e-01 NA 9.1e-01 NA 3.9e-01
7 GTEx Breast Mammary Tissue 0.2460 0.0750 6.9e-04 0.261 NA 0.180 NA 0.246 1.1e-13 NA 1.5e-09 NA 6.7e-13
8 GTEx Breast Mammary Tissue (Female) 0.3253 0.1139 8.0e-03 0.183 NA 0.140 NA 0.196 3.8e-06 NA 5.9e-05 NA 1.7e-06
9 GTEx Cells Transformed fibroblasts 0.3640 0.0490 5.6e-17 0.345 NA 0.341 NA 0.368 1.0e-26 NA 2.3e-26 NA 7.8e-29
10 GTEx Colon Sigmoid 0.2290 0.0690 9.8e-04 0.216 NA 0.242 NA 0.205 3.6e-08 NA 4.6e-09 NA 8.6e-08
11 GTEx Colon Transverse 0.1390 0.0500 5.6e-03 0.024 NA 0.053 NA 0.041 2.4e-02 NA 1.5e-03 NA 5.1e-03
12 GTEx Esophagus Gastroesophageal Junction 0.3200 0.0960 1.3e-03 0.191 NA 0.196 NA 0.143 1.9e-07 NA 1.3e-07 NA 7.8e-06
13 GTEx Esophagus Mucosa 0.3590 0.0630 1.6e-10 0.258 NA 0.259 NA 0.259 2.2e-17 NA 2.1e-17 NA 1.9e-17
14 GTEx Esophagus Muscularis 0.2220 0.0540 7.0e-06 0.226 NA 0.177 NA 0.208 7.7e-14 NA 6.5e-11 NA 8.7e-13
15 GTEx Lung 0.2228 0.0536 7.6e-06 0.148 NA 0.109 NA 0.129 2.2e-11 NA 1.1e-08 NA 4.8e-10
16 GTEx Nerve Tibial 0.2439 0.0459 2.3e-09 0.270 NA 0.252 NA 0.272 2.9e-19 NA 6.9e-18 NA 1.9e-19
17 GTEx Prostate 0.3270 0.1110 5.3e-03 0.021 NA -0.004 NA 0.019 9.4e-02 NA 4.3e-01 NA 1.1e-01
18 GTEx Testis 0.3440 0.1070 5.6e-03 0.122 NA 0.115 NA 0.140 4.5e-06 NA 8.5e-06 NA 8.6e-07
19 GTEx Thyroid 0.3210 0.0610 5.2e-08 0.259 NA 0.252 NA 0.257 7.1e-20 NA 2.9e-19 NA 1.1e-19
20 ROSMAP Brain Pre-frontal Cortex 0.1823 0.0353 2.3e-09 0.120 0.083 0.098 0.115 0.107 3.2e-15 8.5e-11 1.4e-12 1.3e-14 1.1e-13
21 YFS Blood 0.2710 0.0272 0.0e+00 0.224 0.223 0.241 0.227 0.238 1.2e-71 2.9e-71 8.7e-78 8.5e-73 1.0e-76
22 TCGA Breast Invasive Carcinoma 0.0562 0.0205 2.2e-10 0.051 0.050 0.056 NA 0.055 1.3e-10 1.5e-10 1.5e-11 NA 2.3e-11
23 TCGA Colon Adenocarcinoma 0.2140 0.0660 1.1e-08 0.173 0.172 0.151 NA 0.167 3.1e-10 3.5e-10 4.5e-09 NA 6.5e-10
24 TCGA Esophageal Carcinoma 0.1750 0.0800 6.4e-03 0.017 0.039 0.027 NA 0.032 9.0e-02 2.1e-02 4.7e-02 NA 3.3e-02
25 TCGA Kidney Renal Clear Cell Carcinoma 0.0688 0.0259 5.9e-06 0.076 0.066 0.070 NA 0.073 6.9e-09 7.0e-08 2.4e-08 NA 1.4e-08
26 TCGA Brain Lower Grade Glioma 0.1502 0.0511 2.4e-09 0.086 0.094 0.086 NA 0.084 4.8e-10 7.8e-11 5.1e-10 NA 9.5e-10
27 TCGA Lung Adenocarcinoma 0.0403 0.0190 6.3e-04 0.010 0.014 0.013 NA 0.006 2.2e-02 8.8e-03 9.6e-03 NA 5.6e-02
28 TCGA Ovarian Serous Cystadenocarcinoma 0.0950 0.0450 2.8e-04 0.037 0.060 0.065 NA 0.047 1.5e-03 7.1e-05 3.4e-05 NA 3.9e-04
29 TCGA Pancreatic Adenocarcinoma 0.1650 0.0810 4.0e-03 -0.004 0.037 0.021 NA 0.016 5.0e-01 1.1e-02 4.3e-02 NA 7.1e-02
30 TCGA Prostate Adenocarcinoma 0.0991 0.0319 3.8e-10 0.122 0.112 0.109 NA 0.113 1.0e-12 9.7e-12 1.9e-11 NA 7.1e-12
31 TCGA Rectum Adenocarcinoma 0.3060 0.1170 2.6e-03 0.001 0.080 0.134 NA 0.096 3.0e-01 6.4e-03 5.0e-04 NA 3.0e-03
32 TCGA Soft Tissue Sarcoma 0.0740 0.0360 1.8e-03 0.085 0.046 0.057 NA 0.074 9.7e-06 1.0e-03 2.7e-04 NA 3.4e-05
33 TCGA Stomach Adenocarcinoma 0.0760 0.0320 8.0e-05 0.102 0.056 0.077 NA 0.080 7.9e-08 7.1e-05 3.1e-06 NA 2.0e-06
34 TCGA Thyroid Carcinoma 0.1480 0.0460 1.5e-11 0.105 0.117 0.111 NA 0.113 2.1e-10 1.8e-11 6.9e-11 NA 4.5e-11

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34
Bipolar Disorder (2018) 0.3 0.4 3.8 -1.0 0.6 -0.6 -0.5 -0.5 0.2 -0.7 -0.6 -0.6 -0.0 -1.9 0.6 -0.8 -0.4 -0.5 -0.6 -0.1 -0.5 -0.3 -0.5 0.4 -0.2 -0.7 -0.8 -0.7 -1.1 0.0 -0.2 -1.3 -0.3 0.0 -0.4 -0.4 -0.7
Bipolar Disorder or Schizophrenia 4.2 10.3 13.4 -3.5 -3.0 -3.2 -3.1 -3.4 -1.3 -3.4 -3.1 -3.3 -3.1 -3.4 -2.0 -3.5 -3.2 -3.2 -3.3 -3.5 -3.5 -3.3 -3.4 3.5 -3.5 -3.2 -2.2 -3.4 -3.7 -3.0 -2.6 -3.3 -3.4 -3.7 -3.2 -3.2 -3.2
Depressed Affect (Nagel 2018) 0.1 0.3 3.5 -0.2 -0.1 -0.3 -0.7 -0.5 0.1 -0.3 -0.7 -0.3 -0.6 0.0 -0.3 -0.5 -0.5 -0.6 -0.5 -1.9 -0.1 -0.6 -0.3 0.5 -0.5 -0.8 0.0 -0.3 -0.5 -0.9 -0.1 -0.1 -0.6 -0.3 -0.5 -0.5 -0.4
Depression (Nagel 2018) 1.5 2.2 10.6 -1.4 -1.0 -1.4 -1.7 -1.6 -2.2 -1.3 -1.4 -1.3 -1.0 -1.0 -0.9 -1.6 -1.6 -1.5 -1.5 -3.3 -1.5 -1.7 -1.7 1.3 -1.1 -1.6 -1.2 -1.3 -1.4 -1.4 -1.0 -0.3 -1.5 -0.6 -1.6 -1.6 -1.9
Intelligence (Savage-Jansen 2018) 0.3 0.9 4.6 0.6 2.2 0.6 0.6 0.8 1.8 0.5 0.4 0.9 0.1 -1.3 -0.6 0.9 0.9 0.8 0.7 1.5 0.5 1.2 0.4 -0.5 1.6 -0.4 -0.7 0.5 -0.3 1.4 1.6 -0.1 0.7 1.2 0.9 0.9 0.3
Neuroticism (Nagel 2018) 0.0 0.1 1.1 0.2 0.5 0.1 -0.1 0.1 0.3 0.1 -0.1 0.2 -0.2 0.6 -0.2 0.2 0.1 -0.0 0.0 -1.0 0.6 0.0 0.0 0.0 0.2 -0.4 -0.2 0.1 -0.2 -0.0 0.7 0.1 0.0 -0.3 0.1 0.1 -0.0
Schizophrenia (2018) 6.8 14.1 21.5 -3.8 -4.3 -3.7 -3.6 -3.9 -1.8 -3.8 -3.5 -3.9 -4.0 -2.8 -3.1 -3.9 -3.9 -3.8 -3.8 -4.3 -4.1 -4.0 -4.0 4.1 -4.3 -3.6 -2.2 -3.8 -4.0 -3.9 -3.2 -3.1 -4.1 -4.6 -3.9 -3.9 -3.7
Schizophrenia vs Biploar Disorder 1.0 1.4 3.7 -1.0 -1.6 -1.0 -1.0 -1.2 -1.1 -1.1 -0.9 -1.1 -1.5 -0.2 -1.4 -1.1 -1.2 -1.1 -1.1 -1.9 -0.9 -1.2 -1.2 1.4 -1.5 -1.0 -0.3 -1.1 -0.8 -1.5 -1.3 -0.3 -1.2 -1.2 -1.2 -1.2 -0.8
Worry (Nagel 2018) 0.1 0.2 0.8 -0.3 0.2 -0.5 -0.4 -0.2 0.1 -0.3 -0.6 -0.3 -0.5 0.1 -0.8 -0.1 -0.3 -0.4 -0.4 -0.7 -0.5 -0.2 -0.7 0.3 -0.0 -0.6 -0.9 -0.3 -0.0 -0.1 0.5 -0.1 -0.3 -0.4 -0.3 -0.3 -0.1
Alzheimer’s Disease (in mother) 1.7 1.9 5.2 -1.3 -1.1 -1.2 -1.6 -1.6 -0.3 -1.2 -1.4 -1.6 -1.4 -2.3 -1.2 -1.6 -1.6 -1.5 -1.5 -1.7 -1.5 -1.6 -1.3 1.4 -1.2 -1.0 -1.6 -1.2 -0.3 -1.4 -1.6 -0.3 -1.4 -0.0 -1.6 -1.6 -1.5
Alzheimer’s Disease (in father) 1.0 1.1 3.4 0.7 1.6 0.6 1.3 1.1 0.8 0.7 0.9 1.1 0.8 0.2 1.0 1.2 1.2 1.2 1.0 0.5 0.5 1.4 1.0 -1.1 1.1 1.8 1.0 0.7 1.4 1.0 0.3 0.9 1.0 0.8 1.2 1.2 1.0
Alzheimer’s Disease (including proxy) 0.3 0.4 1.4 -0.7 0.2 -1.0 -0.6 -0.7 0.5 -0.6 -0.7 -0.6 -0.7 -1.1 -0.6 -0.7 -0.6 -0.5 -0.7 -1.2 -1.2 -0.5 -0.5 0.6 -0.2 -0.2 -0.9 -0.6 0.2 -0.3 -0.8 -0.3 -0.7 -0.0 -0.6 -0.6 -0.5
Crohns Disease (2017) 1.1 2.4 4.8 -2.2 -1.0 -1.4 -1.5 -1.8 -0.8 -2.2 -1.9 -1.8 -1.3 -1.4 -0.1 -1.7 -1.5 -1.7 -1.9 -2.1 -1.1 -1.5 -1.5 1.7 -1.5 -1.2 -1.2 -2.1 -0.6 -1.6 -2.0 -1.1 -1.5 -0.6 -1.5 -1.5 -1.6
Irritable Bowel Disease (IBD) 3.7 8.9 11.4 -3.3 -2.8 -3.1 -3.2 -3.2 -2.0 -3.3 -3.2 -3.3 -2.8 -2.0 -1.4 -3.3 -3.2 -3.3 -3.3 -2.4 -2.6 -3.3 -3.4 3.3 -3.2 -3.1 -2.7 -3.3 -2.5 -3.2 -3.3 -1.7 -3.1 -2.0 -3.2 -3.2 -3.2
Ulcerative Colitis (UC) 4.5 8.4 12.0 -2.9 -3.2 -3.2 -3.3 -3.0 -1.8 -2.9 -3.0 -3.2 -2.9 -1.4 -2.1 -3.1 -3.2 -3.2 -3.1 -1.6 -2.5 -3.3 -3.5 3.2 -3.1 -3.3 -2.8 -2.9 -3.0 -3.2 -2.8 -1.3 -3.1 -1.9 -3.3 -3.2 -3.3
Major Depression (MDD) 2.4 2.9 8.3 -1.2 -2.9 -1.0 -2.0 -1.9 -0.0 -1.2 -1.0 -1.8 -1.6 -0.8 -2.0 -1.6 -2.0 -1.9 -1.7 -2.2 -2.3 -1.9 -1.5 1.8 -1.9 -1.2 -2.0 -1.2 -1.1 -0.9 -2.1 -2.5 -1.6 -1.0 -2.0 -2.0 -0.9
Reaction Time 0.5 0.9 3.2 1.1 -0.2 0.9 1.0 0.9 -0.2 1.2 1.8 0.9 1.2 -0.2 1.3 0.9 0.9 0.9 1.0 0.9 0.9 0.9 1.0 -1.2 0.7 1.2 0.4 1.2 1.0 1.1 -0.1 0.4 1.1 0.4 0.9 0.9 0.8
Verbal and Numeric Reasoning (VNR) 0.1 0.2 1.6 0.3 0.5 0.1 -0.0 0.3 0.4 0.1 -0.1 0.2 -0.2 -1.2 -0.7 0.2 0.2 0.1 0.2 0.8 0.4 0.2 -0.2 0.1 0.6 -0.8 -0.6 0.1 -0.7 0.3 0.9 0.0 -0.1 -0.0 0.2 0.2 -0.6
Breast Cancer 0.4 1.0 5.3 -0.1 1.8 0.4 0.8 0.6 1.9 -0.1 -0.4 0.5 0.6 -0.2 -0.4 0.7 1.0 0.6 0.3 1.5 1.5 0.9 0.9 -0.4 1.4 0.9 0.3 -0.2 1.6 0.5 0.5 1.2 0.8 2.3 1.0 1.0 0.4
Ovarian Cancer 0.7 0.9 2.9 1.3 0.2 1.2 0.9 1.1 1.0 1.2 1.1 1.0 1.0 -1.0 1.1 1.0 0.9 1.0 1.1 1.4 1.7 0.8 1.0 -0.9 0.8 0.3 1.0 1.2 0.2 0.2 0.5 1.0 0.9 0.8 0.9 0.9 0.9
Prostate Cancer 0.2 0.3 1.7 0.5 0.4 0.3 0.4 0.3 1.3 0.4 0.3 0.5 0.6 -0.1 0.4 0.3 0.5 0.5 0.5 -0.0 0.8 0.6 0.2 -0.3 1.0 -0.1 0.1 0.4 0.2 0.4 0.7 0.9 0.6 1.2 0.5 0.5 0.4
Age at First Birth 1.2 1.7 4.7 -1.5 -1.1 -1.4 -1.3 -1.4 -2.0 -1.3 -0.9 -1.5 -1.0 -0.1 0.4 -1.2 -1.5 -1.5 -1.4 -0.9 -1.1 -1.5 -1.1 1.4 -2.0 -0.5 -0.8 -1.3 -1.1 -1.2 -2.2 -1.4 -1.3 -1.4 -1.5 -1.5 -1.1
Bipolar Disorder (2011) 0.9 0.8 2.2 0.9 0.9 1.1 0.9 1.0 0.9 1.0 1.1 0.9 1.1 -0.2 0.4 1.0 0.9 1.0 1.0 1.5 1.2 0.9 0.9 -1.0 0.8 0.8 0.7 1.0 0.1 0.9 0.9 0.2 1.0 0.3 0.9 0.9 0.6
Body Mass Index (BMI) (2010) 0.3 0.4 1.7 0.4 0.7 0.3 0.1 0.5 1.3 0.4 0.2 0.4 0.3 1.2 0.2 0.6 0.5 0.4 0.3 0.8 0.8 0.4 0.3 -0.4 1.0 0.2 -0.2 0.4 0.8 0.8 0.9 0.7 0.5 1.3 0.4 0.5 0.2
Coronary Artery Disease (CAD) 0.4 0.4 3.8 1.0 0.2 0.4 0.3 0.5 -2.0 0.8 0.8 0.4 -0.5 1.3 0.1 0.4 0.1 0.6 0.6 -0.8 -0.0 0.1 0.4 -0.3 -0.2 0.6 1.0 0.8 0.7 -0.2 0.3 0.3 0.0 -1.4 0.1 0.1 0.5
Crohns Disease (2012) 0.5 0.8 2.7 -0.8 -0.8 -0.9 -0.6 -0.9 -1.1 -1.0 -1.0 -0.8 -0.9 -0.9 -0.1 -0.7 -0.6 -0.9 -0.9 -1.6 -0.2 -0.8 -0.6 0.9 -1.2 -0.4 -0.3 -1.0 -0.3 -1.5 -1.5 -0.2 -1.1 -1.0 -0.6 -0.6 -0.5
Mean Putamen Volume 3.0 3.5 7.8 -1.9 -2.4 -1.6 -1.7 -2.0 -1.3 -1.9 -2.1 -1.9 -1.9 -2.8 -0.1 -2.0 -2.0 -1.8 -1.8 -2.1 -2.2 -1.9 -1.6 2.0 -2.3 -1.3 -1.0 -1.9 -1.2 -2.6 -2.3 0.1 -2.1 -1.1 -2.0 -2.0 -1.5
Fasting Glucose 0.2 0.2 1.4 -0.3 -1.2 -0.5 -0.1 -0.3 0.5 -0.3 0.2 -0.3 -0.3 -0.4 0.1 -0.3 -0.4 -0.3 -0.3 0.3 0.3 -0.4 -0.2 0.4 -0.9 0.2 0.1 -0.3 0.4 -0.5 -1.1 0.3 -0.2 -0.7 -0.4 -0.4 -0.3
HbA1C 0.2 0.2 1.1 -0.3 -0.4 -0.2 -0.6 -0.3 0.4 -0.4 -1.0 -0.4 -0.6 -0.8 -1.1 -0.2 -0.3 -0.4 -0.5 0.1 0.1 -0.4 -0.5 0.4 -0.1 -0.5 -0.4 -0.4 0.3 -0.3 0.5 0.0 -0.4 -0.0 -0.3 -0.3 0.3
HDL Cholesterol 0.4 0.7 2.1 0.4 0.5 0.6 1.0 0.7 1.4 0.5 0.9 0.7 1.1 0.5 1.5 0.7 0.8 0.7 0.6 0.8 0.7 0.9 1.2 -0.8 0.4 1.3 0.6 0.5 0.9 1.1 -0.0 0.1 1.0 0.4 0.8 0.8 1.0
LDL Cholesterol 0.5 0.8 3.5 -0.8 -0.4 -1.0 -0.7 -0.9 -1.4 -1.0 -0.9 -0.7 -0.5 0.2 -1.0 -0.8 -0.6 -0.8 -0.9 -0.6 -1.3 -0.7 -0.7 0.7 -0.6 -1.2 -0.5 -1.0 -1.3 -0.2 0.4 -1.9 -0.7 -1.7 -0.6 -0.6 -0.4
Lupus 1.3 2.0 5.0 -1.0 -0.9 -0.6 -1.6 -1.4 -1.8 -1.1 -1.3 -1.3 -1.6 -0.6 -1.7 -1.5 -1.4 -1.4 -1.4 -2.2 -2.2 -1.5 -1.3 1.2 -0.9 -1.6 -1.3 -1.1 -1.6 -1.0 -0.1 -1.8 -1.5 -2.0 -1.4 -1.4 -1.1
Neuroticism (2016) 0.1 0.1 1.8 -0.0 -0.1 -0.0 -0.2 -0.2 -1.3 -0.3 -0.1 -0.2 0.1 0.0 0.4 0.0 -0.1 -0.5 -0.3 -0.4 -0.4 -0.4 -0.2 -0.0 -0.4 0.7 0.7 -0.3 0.1 0.0 -0.2 0.0 0.1 -0.6 -0.1 -0.1 -0.2
Primary Biliary Cirrhosis 0.9 1.2 3.3 -1.2 -0.5 -1.7 -1.2 -1.1 -1.5 -1.2 -0.9 -1.1 -0.8 0.4 -1.1 -1.1 -1.1 -1.2 -1.2 -0.8 -0.4 -1.1 -1.2 1.0 -0.6 -1.3 -1.1 -1.2 -1.6 -0.1 -0.3 -1.8 -1.0 -1.6 -1.1 -1.0 -1.2
Rheumatoid Arthritis 0.6 0.9 2.2 -0.9 -0.9 -1.0 -0.8 -1.0 -0.7 -0.9 -1.3 -0.9 -0.7 -0.9 -1.0 -1.1 -0.9 -0.9 -0.9 -0.8 -1.4 -1.0 -0.9 0.9 -1.0 -1.2 -0.3 -0.9 -1.0 -1.5 -0.4 0.2 -0.9 -0.4 -0.9 -0.9 -0.7
Schizophrenia (2014) 3.9 8.6 17.3 -2.8 -3.0 -2.5 -2.8 -3.0 -1.8 -2.8 -2.4 -2.9 -3.1 -2.8 -2.4 -2.8 -2.9 -3.0 -2.8 -3.5 -3.8 -3.0 -3.2 3.1 -3.3 -2.8 -2.0 -2.8 -3.5 -2.6 -2.3 -2.8 -3.1 -4.2 -2.9 -2.9 -3.1
Triglycerides 0.1 0.2 1.0 0.2 -0.4 0.3 0.5 0.2 -0.5 0.2 0.3 0.2 0.0 1.0 0.4 0.1 0.2 0.5 0.3 0.4 -0.0 0.2 0.0 -0.4 0.1 0.7 1.0 0.1 0.9 -0.0 0.2 0.1 0.1 -0.5 0.2 0.2 0.5
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.5 -0.7 0.3 -0.3 -0.4 -0.5 -0.4 -0.8 -0.5 -0.6 -0.4 0.8 -0.9 -0.8 -0.5 -0.4 -0.6 0.1 0.5 -0.3 -0.4 0.6 -0.4 -0.3 -0.5 -0.7 -0.6 -0.3 -0.2 -0.8 -0.5 -1.2 -0.5 -0.5 -0.3
Ulcerative Colitis 2.3 3.3 5.9 -1.5 -2.0 -1.8 -2.1 -1.9 -1.9 -1.6 -1.5 -1.8 -1.5 -0.7 -1.2 -2.1 -2.1 -2.0 -1.8 -0.6 -1.9 -2.1 -2.1 1.8 -2.0 -1.9 -1.6 -1.6 -2.4 -1.9 -1.9 -0.6 -1.9 -1.6 -2.1 -2.1 -2.3
Blood Eosinophil Count 0.1 0.4 2.6 -0.0 0.2 -0.2 -0.7 -0.4 -0.7 -0.0 -0.5 -0.2 -1.1 -0.1 -0.8 -0.2 -0.4 -0.5 -0.4 -1.6 -0.8 -0.5 -0.6 0.3 0.3 -1.1 -0.6 -0.0 -0.6 -0.1 1.0 -0.7 -0.8 -1.6 -0.4 -0.4 -0.2
Blood Platelet Count 0.2 2.2 11.7 1.6 0.9 0.9 1.3 1.1 0.5 1.3 1.1 1.4 1.5 3.4 1.3 1.4 1.1 1.1 1.4 0.7 1.4 1.1 1.6 -1.1 1.0 2.3 1.9 1.4 2.4 0.9 0.1 1.8 1.3 2.0 1.1 1.1 2.3
Blood Red Count 1.3 12.4 26.7 3.1 3.3 3.3 3.8 3.7 2.4 3.1 3.0 3.4 3.7 2.0 3.0 3.5 3.7 3.5 3.3 5.2 4.7 3.8 4.0 -3.2 3.1 4.3 3.5 3.1 4.5 2.8 2.1 3.1 3.7 3.4 3.7 3.7 4.0
Blood White Count 0.3 2.3 6.4 1.5 2.0 1.7 1.4 1.5 0.3 1.4 0.9 1.5 1.1 1.5 0.5 1.5 1.5 1.5 1.5 1.6 1.8 1.6 1.6 -1.5 1.7 1.6 1.4 1.4 2.5 1.3 1.2 1.1 1.5 1.9 1.5 1.5 2.0
Heel T-Score 0.6 4.4 12.7 2.1 3.0 2.4 1.5 2.1 3.6 2.4 2.3 2.0 1.4 -0.5 0.1 1.9 1.8 2.0 1.9 2.5 0.8 2.1 1.6 -1.9 2.9 1.7 0.2 2.4 1.9 3.0 2.0 1.8 2.1 3.2 1.8 1.8 1.6
BMI 0.3 1.7 7.7 1.2 1.5 1.6 1.0 1.2 1.0 1.3 0.7 1.2 1.2 0.6 1.3 1.3 1.2 1.1 1.1 0.7 1.1 0.9 0.5 -1.4 1.8 0.9 0.5 1.3 2.0 0.9 1.3 2.8 1.3 2.6 1.2 1.2 0.1
Height 0.2 2.9 8.6 -1.7 -1.5 -2.0 -1.6 -1.9 -1.4 -1.9 -2.1 -1.6 -1.3 -1.3 -0.9 -1.9 -1.7 -1.8 -1.7 -2.0 -0.5 -1.8 -1.8 2.0 -2.2 -1.5 -0.8 -1.9 -1.4 -2.9 -2.6 -0.7 -1.9 -0.2 -1.7 -1.7 -1.2
Waist Hip Ratio (WHR) 0.1 0.6 2.8 0.7 0.7 0.7 0.7 0.9 0.1 0.8 0.4 0.7 0.6 0.1 -0.8 0.7 0.7 0.8 0.8 0.9 0.7 0.8 0.6 -0.6 0.8 0.5 0.6 0.9 1.2 0.3 0.8 1.7 0.8 0.9 0.7 0.7 1.0
Systolic Blood Pressure 0.1 0.6 2.4 0.3 0.7 0.7 0.7 0.7 0.1 0.4 0.4 0.7 0.2 1.4 0.9 0.6 0.7 0.7 0.6 1.6 1.0 0.7 1.0 -0.5 0.7 1.1 1.1 0.4 1.4 0.2 0.2 1.3 0.6 0.6 0.7 0.7 0.7
Smoking Status 1.3 3.0 6.9 1.8 2.2 1.7 1.5 1.8 1.7 1.9 2.1 1.7 1.5 1.8 0.9 1.9 1.7 1.8 1.8 1.9 1.4 1.8 1.8 -1.8 2.3 1.7 0.8 1.8 1.6 2.6 1.8 0.8 1.8 1.8 1.7 1.7 1.1
Allergy or Eczema 0.1 0.4 2.2 0.3 -0.2 0.6 0.4 0.3 -1.4 0.3 -0.0 0.2 0.7 -1.5 0.6 0.6 0.4 0.5 0.5 -0.5 0.9 0.3 0.3 -0.5 0.5 0.3 1.0 0.3 0.1 -0.8 0.1 0.8 0.2 0.8 0.4 0.4 -0.1
Cardiovascular Disease 0.1 0.4 1.5 -1.2 -0.4 -0.5 -0.7 -0.5 0.3 -1.1 -1.1 -0.8 -0.4 0.4 -0.7 -0.7 -0.5 -0.7 -0.9 0.3 -0.3 -0.8 -1.0 0.6 -0.0 -0.3 -0.2 -1.1 0.7 -0.2 -0.1 0.3 -0.6 -0.2 -0.5 -0.5 -1.2
Hypothyroidism (self reported) 0.2 0.4 1.2 0.6 0.5 0.4 0.6 0.5 0.1 0.6 0.6 0.5 0.6 1.0 0.8 0.6 0.5 0.6 0.6 0.3 0.7 0.7 0.6 -0.7 0.2 1.1 0.4 0.6 1.1 0.4 -0.4 0.5 0.6 0.9 0.5 0.5 0.9
Respiratory disease 0.2 0.5 2.8 0.1 0.3 0.3 0.6 0.3 -1.7 -0.0 -0.1 0.1 -0.1 -1.3 1.3 0.5 0.6 0.4 0.3 -1.5 0.5 0.3 0.5 -0.3 -0.3 0.6 1.3 0.0 1.2 -1.0 -0.2 0.7 0.1 -0.8 0.6 0.6 0.3
Type 2 Diabetes (T2D) (2018) 0.9 1.7 3.8 1.2 1.5 1.9 1.3 1.5 0.2 1.3 1.5 1.5 1.2 0.7 1.3 1.5 1.4 1.3 1.4 1.9 1.7 1.2 0.6 -1.4 1.3 1.1 1.4 1.3 1.0 1.1 1.0 1.1 1.2 0.6 1.4 1.4 0.7
Lung FEV1/FVC ratio 0.8 3.8 8.4 -2.0 -1.8 -1.8 -2.2 -2.2 0.0 -2.1 -2.1 -2.1 -1.7 -1.1 -2.9 -2.1 -2.1 -2.1 -2.1 -1.3 -2.4 -2.1 -2.4 2.0 -1.5 -2.2 -2.2 -2.1 -1.8 -1.6 -1.8 -2.1 -1.9 0.2 -2.1 -2.1 -1.9
Lung FVC 0.3 1.3 2.8 1.7 0.6 0.8 1.3 1.2 0.5 1.5 1.7 1.2 1.1 -0.1 1.0 1.4 1.1 1.3 1.4 1.4 1.2 1.2 1.3 -1.2 0.6 1.0 1.0 1.5 0.6 1.0 0.6 0.3 1.2 0.6 1.1 1.1 1.5
Neuroticism 0.1 0.2 1.0 0.3 0.6 0.4 0.2 0.3 0.7 0.3 -0.0 0.4 0.3 0.5 0.3 0.5 0.4 0.3 0.3 -0.9 0.5 0.3 0.2 -0.3 0.5 -0.2 0.2 0.3 -0.0 0.2 1.0 0.5 0.3 0.1 0.4 0.4 0.3
Chronotype (morning person) 1.1 2.5 10.5 1.3 1.8 1.6 1.7 1.3 0.7 1.3 1.8 1.6 1.5 3.2 1.3 1.4 1.6 1.5 1.5 -0.0 0.9 1.4 2.2 -1.6 1.0 2.5 2.2 1.4 1.8 1.5 0.8 1.0 1.6 0.6 1.6 1.6 1.2
Hair Pigment 0.0 1.2 5.5 -1.2 -0.2 -1.3 -1.0 -1.2 -0.9 -1.2 -0.8 -1.2 -0.9 0.6 -0.6 -1.3 -1.0 -1.1 -1.2 -2.4 -1.2 -1.2 -1.0 0.9 -1.2 -0.1 -0.3 -1.2 -0.8 -1.1 -1.2 -0.8 -1.0 -1.0 -1.0 -1.0 -1.2
Tanning 0.0 0.1 0.9 -0.1 0.7 -0.5 -0.2 -0.1 0.5 -0.2 0.1 -0.1 -0.1 1.0 0.9 -0.3 -0.2 -0.2 -0.2 -0.2 0.1 -0.2 -0.0 0.1 -0.2 0.2 0.0 -0.2 0.1 0.7 0.3 -0.4 -0.1 -0.5 -0.2 -0.2 -0.3
Hand grip strength (left) 0.2 0.6 3.3 0.4 -1.6 0.6 0.7 0.5 0.2 0.3 -0.2 0.3 0.7 -1.7 0.9 0.4 0.5 0.4 0.5 1.3 1.0 0.3 0.5 -0.1 -0.6 0.1 1.2 0.3 0.7 -1.4 -0.5 1.8 0.4 0.7 0.5 0.5 0.6
Number of treatments/medications taken 0.8 1.4 5.2 0.7 0.7 0.9 1.4 1.1 -0.3 0.9 1.0 0.9 1.2 -0.0 2.0 1.0 1.2 1.0 1.0 0.6 1.5 0.9 1.2 -0.9 -0.0 1.9 2.0 0.9 2.3 -0.4 -0.9 1.8 1.0 1.1 1.1 1.2 1.4
Average weekly spirits intake 1.8 2.3 4.1 -1.2 -1.2 -0.9 -1.9 -1.7 -0.3 -1.3 -1.4 -1.6 -2.0 -1.2 -0.8 -1.6 -1.8 -1.8 -1.6 -1.4 -1.5 -1.8 -1.6 1.7 -1.7 -1.6 -1.4 -1.3 -1.3 -1.8 -1.5 -0.6 -1.7 -0.8 -1.8 -1.8 -1.6
Sensitivity / hurt feelings 0.2 0.4 3.2 0.6 1.3 0.5 -0.0 0.4 1.0 0.5 0.1 0.4 0.1 0.2 -0.6 0.5 0.3 0.3 0.3 -0.1 0.7 0.4 -0.2 -0.3 0.9 -0.8 -0.9 0.5 -0.5 1.2 1.8 -0.9 0.3 -0.4 0.3 0.3 0.4
Frequency of depressed mood in last 2 weeks 0.4 0.6 3.4 -0.8 0.1 -0.8 -0.9 -0.8 -1.5 -0.6 -0.7 -0.5 -0.3 -0.3 -0.4 -0.8 -0.7 -0.7 -0.7 -1.8 -0.6 -0.8 -1.0 0.4 -0.2 -0.7 -0.7 -0.7 -0.5 -0.3 -0.1 0.0 -0.7 0.1 -0.7 -0.7 -1.3
Hearing difficulty/problems: Yes 0.2 0.4 4.0 0.1 0.1 0.3 0.1 -0.0 -1.2 -0.0 -0.5 0.2 -0.0 -0.8 1.2 0.1 0.1 0.1 0.1 -0.5 0.4 0.1 -0.1 -0.0 -0.1 0.3 0.6 -0.0 0.7 -1.0 -0.5 2.0 0.0 1.3 0.1 0.1 -0.2
Relative age of first facial hair 0.1 0.3 2.2 0.4 0.0 0.5 -0.5 -0.0 0.5 0.4 -0.0 0.0 -0.2 -1.5 -0.3 -0.2 -0.3 -0.1 0.1 -0.7 0.6 -0.1 -0.6 -0.0 0.4 -0.9 -1.1 0.5 -0.3 -0.2 0.2 0.5 -0.1 0.9 -0.3 -0.3 -0.5
Other serious medical condition/disability diagnosed by doctor 0.2 0.2 1.4 -0.4 -1.1 -0.0 0.0 -0.2 -0.7 -0.2 0.1 -0.2 -0.3 -0.4 0.4 -0.1 -0.1 -0.1 -0.2 -1.2 -0.3 -0.2 0.2 0.2 -0.7 0.2 0.3 -0.2 0.4 -0.4 -0.9 -0.5 -0.3 -0.9 -0.1 -0.1 -0.2
Ever used hormone-replacement therapy (HRT) 0.5 0.7 2.2 -0.7 -0.2 -0.9 -0.8 -0.8 0.4 -0.7 -0.4 -1.0 -0.9 -1.4 -0.3 -0.8 -0.8 -0.8 -0.8 -1.3 -0.6 -0.7 -0.9 0.8 -0.5 -0.5 -1.5 -0.7 -0.2 -0.4 -1.2 -0.8 -0.8 -0.3 -0.8 -0.8 -1.1
Ever had hysterectomy (womb removed) 0.4 0.5 1.8 -0.5 -0.5 -0.6 -0.7 -0.7 -0.9 -0.7 -0.7 -0.6 -0.6 1.0 -0.6 -0.4 -0.6 -0.7 -0.7 -0.7 -0.5 -0.6 -0.7 0.4 -0.1 -1.3 -0.9 -0.7 -0.9 -0.1 -0.0 -1.3 -0.6 -0.4 -0.6 -0.6 -0.8
Systolic blood pressure, automated reading 0.1 0.2 1.1 -0.0 0.9 0.1 0.3 0.3 0.7 0.0 -0.2 0.2 -0.2 0.6 -0.5 0.2 0.3 0.3 0.2 1.0 0.5 0.4 0.4 -0.1 0.7 0.0 -0.2 0.0 0.5 0.1 0.2 0.2 0.1 0.5 0.3 0.3 0.1
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 3.1 0.4 0.3 0.6 0.6 0.7 0.3 0.5 0.4 0.7 0.4 1.8 0.9 0.8 0.6 0.6 0.6 1.0 0.7 0.6 0.4 -0.3 0.7 0.6 0.9 0.5 1.4 0.2 0.4 1.7 0.6 1.2 0.6 0.6 0.7
Angina 0.2 0.3 4.0 -0.1 0.8 0.4 0.3 0.3 -2.0 0.2 0.1 0.3 -0.1 1.3 0.3 0.3 0.3 0.2 0.3 0.2 0.4 0.2 0.4 -0.2 0.3 0.3 0.6 0.2 0.4 0.3 0.9 0.7 0.1 -1.0 0.3 0.3 -0.1
Medication for hormone replacement therapy 2.9 3.3 5.3 -1.7 -2.2 -1.7 -1.9 -2.1 -1.0 -1.8 -1.6 -2.0 -1.8 -1.5 -0.8 -2.0 -2.1 -2.0 -2.0 -2.3 -1.7 -2.2 -2.0 2.0 -2.1 -1.1 -0.7 -1.8 -1.2 -2.1 -2.1 -0.1 -2.0 -1.5 -2.1 -2.1 -1.7
Vitamin and mineral supplements 1.7 2.2 4.5 1.3 1.5 1.9 1.5 1.4 0.4 1.3 1.0 1.6 1.6 2.1 0.5 1.4 1.5 1.5 1.4 1.8 1.0 1.4 1.3 -1.7 1.5 1.5 2.1 1.3 1.3 1.3 1.9 2.0 1.6 1.1 1.5 1.5 1.5
Supplements: Zinc 2.2 2.4 5.3 -1.9 -1.4 -1.7 -1.4 -1.6 0.1 -1.7 -1.5 -1.7 -1.6 -2.3 -0.5 -1.7 -1.6 -1.6 -1.7 -1.0 -1.5 -1.4 -1.5 1.8 -1.6 -1.3 -1.5 -1.7 -1.2 -1.8 -2.3 -1.4 -1.6 -0.8 -1.6 -1.6 -0.9
Medication: Co-codamol 0.4 0.4 2.2 -0.3 -0.8 -0.4 -0.4 -0.4 -1.5 -0.3 -0.1 -0.5 -0.6 -0.1 0.8 -0.6 -0.6 -0.6 -0.5 -0.0 -0.5 -0.8 0.1 0.7 -1.3 0.5 0.4 -0.3 0.7 -1.0 -1.4 0.6 -0.6 -0.7 -0.6 -0.6 -0.1
Medication: Metformin 3.2 4.6 6.2 2.2 2.2 2.2 2.3 2.3 2.1 2.3 2.3 2.4 2.5 0.9 1.6 2.4 2.3 2.3 2.3 1.8 2.3 2.3 2.2 -2.3 2.4 2.0 1.6 2.3 1.8 2.1 1.6 1.2 2.3 2.2 2.3 2.3 2.0
Diabetes (father) 1.1 1.4 3.4 1.5 1.7 0.9 1.0 1.1 1.8 1.4 1.5 1.3 1.3 -0.9 0.0 1.2 1.1 1.1 1.3 0.5 0.7 1.2 1.1 -1.4 1.6 0.5 0.3 1.4 0.2 1.5 1.1 0.1 1.2 1.6 1.1 1.1 0.9
Diabetes (mother) 0.5 0.7 2.9 1.2 0.4 0.9 0.7 0.7 -0.2 1.2 1.4 0.7 0.5 -0.2 1.7 0.9 0.6 0.7 0.9 -0.3 -0.3 0.7 1.2 -0.9 -0.1 1.2 0.5 1.2 0.6 0.5 -0.4 -0.0 0.7 0.1 0.6 0.6 1.3
Severe depression (siblings) 1.9 2.1 4.9 -1.4 -2.0 -1.7 -1.4 -1.5 -1.3 -1.6 -1.7 -1.5 -1.1 -1.1 -0.8 -1.5 -1.3 -1.4 -1.4 -2.2 -2.1 -1.5 -1.5 1.4 -1.1 -1.7 -1.1 -1.6 -1.1 -1.7 -0.9 -0.3 -1.4 -1.0 -1.3 -1.3 -1.8
Pack years adult smoking proportion 0.4 0.6 2.5 0.4 0.9 0.6 0.7 0.7 -0.2 0.4 0.1 0.7 0.3 1.2 0.6 0.8 0.9 0.7 0.5 0.9 0.6 0.8 0.5 -0.7 1.0 0.4 0.6 0.4 1.3 0.9 1.6 0.6 0.7 0.4 0.9 0.9 0.6
Impedance of leg (right) 0.1 0.5 6.2 -0.6 -0.6 -0.6 -0.1 -0.4 -0.5 -0.7 -0.1 -0.4 -0.7 -0.0 0.5 -0.6 -0.3 -0.4 -0.5 -0.2 -0.6 -0.2 0.1 0.6 -1.1 0.1 0.2 -0.7 -0.8 0.1 -0.3 -1.9 -0.5 -2.5 -0.3 -0.3 0.2
Leg fat-free mass (left) 0.1 0.4 5.6 0.5 0.2 0.3 0.0 0.2 -0.2 0.4 -0.2 0.3 0.3 -1.1 0.5 0.4 0.2 0.2 0.3 0.2 0.7 0.0 -0.3 -0.2 0.3 0.0 0.1 0.4 1.1 -0.8 -0.3 2.4 0.2 2.0 0.2 0.2 -0.3
Trunk fat percentage 0.3 1.3 5.3 1.1 1.5 1.7 1.0 1.1 -1.0 1.2 1.0 1.1 0.6 0.9 1.4 1.1 1.0 0.9 1.1 0.0 0.6 0.8 1.1 -0.9 0.9 1.5 1.2 1.2 2.0 0.4 0.6 2.3 0.9 0.9 1.0 1.0 0.6
Hand grip strength (right) 0.3 0.8 4.9 0.6 -1.5 0.6 0.9 0.7 0.7 0.4 -0.1 0.6 0.7 -1.7 0.8 0.6 0.6 0.6 0.7 1.5 0.8 0.5 0.8 -0.2 -0.2 0.3 1.4 0.4 0.6 -1.4 -0.6 2.2 0.5 1.2 0.6 0.7 0.9
Townsend deprivation index at recruitment 0.9 1.2 7.9 0.9 0.6 1.1 0.9 0.9 0.2 0.9 0.8 1.0 0.5 0.5 0.9 0.9 0.9 0.8 0.7 1.7 1.0 0.7 1.2 -0.8 0.5 1.7 1.6 0.9 2.8 0.4 0.2 2.2 0.9 1.2 0.9 0.9 1.3
Current tobacco smoking 2.0 3.3 8.5 1.6 1.4 1.6 1.8 1.9 1.5 1.7 1.8 1.8 1.4 0.3 2.4 1.8 1.8 1.8 1.8 2.9 1.6 1.8 2.1 -1.7 2.0 2.0 1.8 1.7 1.9 1.9 1.6 1.8 1.9 1.9 1.8 1.8 1.5
Average weekly fortified wine intake 0.1 0.1 0.5 0.3 -0.2 0.3 0.2 0.1 0.7 0.0 -0.1 0.1 0.5 -0.1 0.1 0.3 0.2 0.2 0.2 -0.3 0.5 0.3 0.2 -0.3 -0.0 0.2 -0.0 0.0 0.3 -0.1 -0.2 -0.1 0.2 0.6 0.2 0.2 0.3
Maternal smoking around birth 0.3 0.5 2.8 -0.7 -0.3 -0.5 -0.7 -0.7 -0.7 -0.6 -1.0 -0.5 -0.8 1.7 -1.1 -0.6 -0.6 -0.5 -0.6 -0.7 -0.5 -0.8 -0.6 0.6 -0.2 -0.7 0.3 -0.6 0.1 -0.4 0.6 0.2 -0.8 -0.8 -0.6 -0.6 -0.9
Fed-up feelings 0.1 0.1 0.7 0.2 -0.4 -0.2 -0.2 -0.1 0.6 0.1 -0.4 0.1 -0.2 0.3 0.5 0.1 -0.1 -0.1 0.0 -0.6 -0.3 -0.1 -0.1 0.1 0.0 -0.7 -0.0 0.1 -0.6 -0.5 0.3 0.8 -0.1 0.6 -0.1 -0.1 0.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.1 3.7 -1.1 -0.5 -1.0 -1.3 -1.2 -1.5 -0.9 -0.8 -1.0 -0.7 -0.4 -0.3 -1.1 -1.1 -1.2 -1.1 -1.9 -0.8 -1.2 -1.2 0.8 -0.7 -1.4 -1.2 -0.9 -1.3 -0.6 -0.3 -0.4 -1.0 -0.7 -1.1 -1.1 -1.8
Relative age voice broke 0.7 1.0 4.1 1.1 0.6 1.6 1.0 1.1 0.6 1.2 0.9 1.1 1.1 -1.1 0.7 1.0 1.0 1.0 1.1 0.8 2.0 1.1 0.6 -1.0 0.6 0.4 0.6 1.2 1.0 0.2 0.6 1.3 1.1 1.2 1.0 1.0 0.8
Taking other prescription medications 0.2 0.3 2.8 0.3 -0.0 0.2 0.6 0.5 0.8 0.4 0.4 0.2 0.3 0.0 0.7 0.2 0.4 0.4 0.4 0.8 0.5 0.3 0.7 -0.2 -0.4 1.1 0.8 0.4 1.7 -0.2 -0.6 0.4 0.3 0.2 0.4 0.4 1.0
Age when periods started (menarche) 0.1 0.2 1.4 -0.5 -0.7 -0.4 -0.2 -0.2 -1.2 -0.3 -0.4 -0.3 -0.4 -0.7 0.1 -0.4 -0.3 -0.3 -0.3 0.2 -0.7 -0.1 -0.5 0.4 -0.5 -0.3 -0.3 -0.3 0.2 -0.5 -0.4 0.7 -0.2 0.3 -0.3 -0.3 -0.2
Bilateral oophorectomy (both ovaries removed) 2.3 2.6 4.4 1.8 1.2 1.8 1.5 1.6 0.7 1.7 1.7 1.7 1.6 1.9 1.8 2.0 1.6 1.5 1.5 1.3 1.7 1.5 1.5 -1.9 1.5 1.7 1.6 1.7 2.1 1.5 1.7 2.1 1.6 0.9 1.6 1.6 1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 1.2 0.3 0.4 0.4 0.5 0.4 0.7 0.5 0.5 0.4 0.2 -0.5 0.8 0.3 0.4 0.4 0.4 0.6 0.7 0.4 0.3 -0.2 0.4 0.6 0.5 0.5 0.9 0.1 0.1 1.1 0.4 1.1 0.4 0.4 0.6
Tinnitus: Yes, but not now, but have in the past 0.5 0.5 1.6 0.3 0.6 0.5 0.9 0.7 0.5 0.2 0.2 0.7 1.1 -0.2 0.6 0.8 1.0 0.9 0.6 0.0 -0.0 0.9 0.5 -0.9 0.7 1.3 0.8 0.2 1.1 0.4 0.1 0.8 0.8 1.1 1.0 1.0 0.3
Qualifications: CSEs or equivalent 1.9 2.5 8.4 1.5 0.7 1.4 1.3 1.3 0.8 1.5 1.3 1.5 1.4 2.9 2.4 1.4 1.3 1.4 1.5 0.9 1.8 1.4 1.6 -1.5 1.6 1.6 1.2 1.5 1.5 1.7 1.6 1.4 1.8 2.7 1.3 1.3 1.6
Serious illness, injury or assault to yourself 0.1 0.1 2.2 0.4 -0.3 -0.1 0.1 0.1 -0.6 0.3 0.0 0.1 0.5 1.5 0.3 0.1 0.1 0.1 0.2 -0.1 -0.2 -0.0 0.0 -0.2 -0.2 -0.1 0.3 0.3 0.1 -0.3 0.4 0.4 0.2 0.1 0.1 0.1 0.0
High blood pressure 0.4 1.1 2.4 -1.4 -0.1 -0.9 -1.3 -1.1 -0.5 -1.3 -1.5 -1.1 -1.1 0.1 -1.3 -1.2 -1.0 -1.1 -1.2 -0.7 -1.2 -1.1 -1.4 1.1 -0.2 -1.2 -1.1 -1.3 -0.0 -0.6 -0.2 -0.2 -1.1 -0.3 -1.0 -1.0 -1.5
Hayfever, allergic rhinitis or eczema 0.2 0.4 2.7 -0.2 -0.9 -0.3 -0.5 -0.4 -1.6 -0.3 -0.6 -0.5 -0.5 -1.5 -0.0 -0.2 -0.5 -0.4 -0.3 -0.7 0.1 -0.6 -0.7 0.4 -0.6 -0.8 -0.1 -0.3 -0.8 -1.2 -0.2 0.2 -0.5 -0.2 -0.5 -0.5 -0.9
Multivitamins +/- minerals 1.1 1.4 5.8 -0.4 -0.1 -1.3 -1.3 -0.9 -0.0 -0.5 -0.4 -1.1 -1.3 -2.3 -1.1 -1.0 -1.1 -1.1 -0.8 -1.6 -0.8 -0.9 -0.9 0.9 -0.5 -1.7 -2.4 -0.5 -1.9 -0.4 -1.0 -2.0 -1.1 -0.5 -1.1 -1.1 -1.1
Stomach or abdominal pain in last month 2.0 2.5 4.2 -1.8 -1.5 -1.6 -1.5 -1.8 -1.6 -1.7 -1.7 -1.8 -1.0 -1.9 -1.3 -1.9 -1.7 -1.7 -1.6 -1.2 -1.7 -1.8 -2.1 1.5 -1.7 -1.2 -0.7 -1.7 -1.6 -1.8 -1.7 -0.5 -1.5 -0.8 -1.7 -1.7 -1.6
Supplements: Glucosamine 0.2 0.2 1.7 -0.1 0.0 -0.5 -0.1 -0.2 0.4 -0.1 -0.1 -0.3 -0.3 -1.3 -0.2 -0.2 -0.3 -0.2 -0.1 -0.6 -0.2 -0.3 -0.1 0.4 -0.6 0.2 0.4 -0.1 0.1 -1.1 -1.1 0.5 -0.2 0.8 -0.3 -0.3 0.0
Diverticular disease/diverticulitis (self-reported) 1.0 1.2 2.7 1.2 1.1 1.1 1.0 1.0 0.3 1.2 1.0 1.0 1.4 0.7 1.2 1.3 1.1 1.1 1.2 0.7 1.4 1.2 1.0 -1.2 1.2 0.4 0.4 1.2 0.6 1.5 1.6 0.3 1.3 1.0 1.1 1.1 0.8
Medication: Atenolol 0.1 0.2 1.4 -0.4 0.0 -0.5 -0.4 -0.3 -1.2 -0.4 -0.4 -0.5 -0.4 -0.2 -0.5 -0.5 -0.4 -0.4 -0.4 -0.0 -0.5 -0.5 -0.4 0.5 -0.4 0.1 0.2 -0.4 0.3 -0.4 -0.3 0.7 -0.4 0.1 -0.4 -0.4 -0.5
Medication: Levothyroxine sodium 0.1 0.1 1.5 0.0 0.5 -0.2 -0.2 -0.1 0.6 0.1 0.3 -0.2 -0.3 1.2 -0.5 -0.2 -0.3 -0.1 -0.1 0.1 -0.0 -0.2 -0.1 -0.0 -0.4 0.3 -0.4 0.1 0.5 0.2 -0.5 -0.5 -0.2 -0.2 -0.3 -0.3 0.2
Sitting height 0.2 1.5 6.0 -1.1 -1.6 -1.1 -0.9 -1.2 -2.5 -1.3 -1.6 -1.1 -0.9 -2.0 0.0 -1.0 -1.0 -1.1 -1.1 -1.1 -0.1 -1.1 -1.3 1.3 -1.5 -1.0 -0.5 -1.3 -0.7 -2.2 -1.7 0.4 -1.2 -0.6 -1.0 -1.0 -0.8
Chronic bronchitis/emphysema (father) 1.6 1.9 4.4 1.3 1.0 1.1 1.6 1.5 -0.3 1.3 1.3 1.4 1.4 1.3 2.0 1.6 1.5 1.4 1.4 1.5 2.1 1.4 1.6 -1.7 0.9 1.6 1.7 1.3 1.5 1.0 1.1 0.9 1.3 -0.3 1.5 1.5 1.2
High blood pressure (mother) 0.1 0.2 1.4 0.5 0.0 0.3 0.2 0.2 0.1 0.4 0.2 0.2 0.6 0.4 0.9 0.4 0.2 0.3 0.4 -0.1 -0.4 0.1 0.3 -0.4 0.2 0.4 0.7 0.4 0.4 -0.1 0.1 1.2 0.3 0.8 0.2 0.2 0.0
Body mass index (BMI) 0.2 1.0 4.3 1.0 1.7 1.2 0.7 0.9 0.2 1.0 0.7 0.9 0.7 0.5 0.8 1.0 0.9 0.8 0.9 0.4 0.5 0.7 0.6 -0.9 1.4 0.9 0.4 1.0 1.6 0.8 1.0 2.1 0.9 1.6 0.9 0.9 -0.0
Impedance of leg (left) 0.1 0.7 6.3 -0.8 -0.6 -0.7 -0.3 -0.6 -0.3 -0.8 -0.3 -0.7 -0.9 -0.2 -0.2 -0.9 -0.6 -0.6 -0.7 -0.4 -0.9 -0.5 -0.2 0.9 -1.2 -0.2 0.0 -0.9 -1.1 -0.1 -0.4 -2.2 -0.8 -2.5 -0.6 -0.6 0.0
Leg predicted mass (left) 0.1 0.4 5.3 0.4 0.1 0.2 -0.0 0.2 -0.3 0.3 -0.3 0.2 0.3 -1.1 0.4 0.3 0.1 0.1 0.2 0.1 0.7 -0.0 -0.3 -0.2 0.2 -0.0 0.0 0.3 1.1 -0.8 -0.4 2.3 0.1 1.9 0.1 0.1 -0.4
Trunk fat mass 0.2 1.0 5.9 1.0 1.2 1.4 0.8 1.0 -0.8 1.1 0.8 0.9 0.6 0.2 1.2 1.0 0.9 0.8 0.9 0.2 0.8 0.7 0.8 -0.8 0.8 1.2 0.9 1.1 1.9 0.1 0.3 2.4 0.8 1.3 0.9 0.9 0.4
Waist circumference 0.1 0.4 5.0 0.3 1.2 0.5 0.1 0.3 -0.3 0.3 -0.2 0.2 -0.0 -0.9 -0.2 0.4 0.3 0.1 0.3 -0.0 0.1 0.2 -0.0 -0.1 0.6 0.2 -0.2 0.3 1.3 -0.5 0.0 2.2 0.2 1.8 0.3 0.3 -0.4
Number of incorrect matches in round 0.7 1.2 7.5 -0.8 -1.2 -1.1 -0.7 -0.7 -1.8 -0.7 -0.6 -0.8 -1.0 0.0 -1.3 -0.6 -0.7 -0.7 -0.8 -1.5 -1.1 -0.7 -0.5 0.9 -1.2 -1.1 -0.8 -0.7 -1.2 -0.5 -0.4 -2.6 -1.0 -2.7 -0.7 -0.7 -0.1
Past tobacco smoking 0.2 0.3 2.0 -0.4 -1.2 -0.6 -0.3 -0.4 -0.5 -0.4 -0.7 -0.4 -0.8 -1.4 0.5 -0.5 -0.4 -0.4 -0.4 -0.4 0.3 -0.4 -0.3 0.6 -0.7 -0.4 0.1 -0.4 -0.2 -1.2 -0.4 0.4 -0.6 -0.8 -0.4 -0.4 0.3
Alcohol usually taken with meals 0.7 1.1 7.5 -0.8 -1.6 -1.0 -0.7 -1.1 0.7 -0.9 -0.3 -1.0 -0.7 -1.6 -0.2 -1.0 -1.0 -1.0 -0.9 -0.9 -1.0 -0.9 -0.4 1.1 -1.8 -0.0 -0.7 -0.9 -0.8 -1.2 -2.7 -1.4 -0.9 -0.4 -1.0 -1.0 -0.2
Nervous feelings 0.1 0.2 2.2 0.2 0.7 0.3 0.1 0.3 0.2 0.2 0.5 0.1 -0.1 0.5 -0.1 0.2 0.3 0.0 0.0 0.3 0.6 0.3 0.1 -0.3 0.1 0.0 -0.7 0.2 0.2 1.1 0.6 -1.5 0.2 -1.1 0.3 0.3 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 1.9 0.3 1.3 0.1 0.3 0.4 -1.4 0.4 0.4 0.5 0.6 1.4 -0.1 0.4 0.6 0.4 0.3 -0.5 -0.6 0.4 0.3 -0.7 0.8 0.5 0.2 0.4 0.3 1.1 1.3 -0.5 0.4 -0.6 0.6 0.6 -0.1
Hearing difficulty/problems with background noise 0.2 0.3 2.4 -0.3 -0.1 -0.1 -0.2 -0.3 -1.1 -0.3 -0.7 -0.2 0.1 -0.7 0.8 -0.3 -0.2 -0.2 -0.2 -0.6 0.6 -0.1 -0.3 0.2 0.1 -0.1 -0.2 -0.3 0.6 -0.7 -0.5 1.4 -0.0 1.5 -0.2 -0.2 -0.2
Hair/balding pattern: Pattern 2 4.0 5.1 8.4 2.1 2.2 2.3 2.3 2.4 1.4 2.3 2.1 2.5 2.6 2.0 1.6 2.3 2.5 2.5 2.3 2.2 2.8 2.5 2.0 -2.6 2.9 1.5 1.6 2.3 1.9 2.8 2.9 1.4 2.4 1.9 2.5 2.5 1.9
Had menopause 0.9 1.1 3.9 0.7 1.6 0.6 1.2 1.0 2.0 0.8 0.8 0.9 1.0 -0.0 -0.4 1.1 1.2 1.2 1.0 0.9 0.6 1.2 0.7 -1.1 1.3 0.9 0.5 0.8 1.2 0.6 0.1 0.7 1.0 2.0 1.2 1.2 0.9
Had other major operations 0.2 0.2 2.1 -0.3 -1.3 0.1 -0.2 -0.0 -0.3 -0.2 -0.5 -0.3 -0.3 -0.9 -0.5 -0.3 -0.3 -0.2 -0.2 0.4 0.3 -0.5 -0.4 0.4 -0.8 -0.2 0.6 -0.2 0.1 -1.4 -0.3 0.3 -0.5 -0.5 -0.3 -0.3 -0.3
Forced vital capacity (FVC) 1.0 3.7 7.6 2.3 1.3 2.0 2.0 2.1 1.8 2.0 1.9 2.1 2.1 0.1 1.6 2.1 2.0 2.1 2.1 2.4 2.8 2.1 1.7 -1.9 1.8 1.5 1.7 2.0 1.7 1.5 1.6 1.9 2.1 2.0 2.0 2.0 1.8
Heel bone mineral density (BMD) T-score, automated (right) 0.4 0.9 2.2 0.7 0.9 0.9 0.9 1.0 1.5 0.8 0.8 0.9 0.7 -0.0 0.6 0.8 1.0 0.9 0.9 1.5 1.3 1.1 0.5 -0.8 1.2 0.7 0.4 0.8 1.0 1.3 1.0 0.7 1.0 1.4 1.0 1.0 0.9
Ever unenthusiastic/disinterested for a whole week 2.4 2.9 5.9 -1.9 -1.3 -2.1 -1.8 -1.9 -0.7 -1.9 -1.7 -1.9 -1.3 0.1 -1.7 -2.0 -1.8 -1.9 -1.9 -1.2 -2.2 -2.0 -1.8 1.7 -2.1 -0.8 -1.1 -1.9 -1.1 -2.0 -2.4 -0.4 -1.8 -0.8 -1.8 -1.8 -2.2
Qualifications: None of the above 0.7 1.4 8.5 1.3 1.6 1.2 0.7 1.1 0.1 1.5 1.0 1.1 0.6 2.9 0.8 0.8 0.8 1.0 1.1 1.2 1.0 0.7 0.9 -1.2 1.2 0.9 1.1 1.5 1.8 1.3 1.7 1.5 0.9 0.9 0.8 0.8 1.0
Financial difficulties in last 2 years 0.1 0.1 1.5 0.2 -0.4 -0.4 0.1 0.1 -1.2 0.2 0.2 0.0 0.0 0.5 0.6 0.1 0.1 0.1 0.1 -0.3 -0.2 -0.0 0.1 -0.1 -0.2 0.3 0.2 0.2 0.6 -0.1 -0.0 0.8 0.1 0.1 0.1 0.1 -0.2
Mouth/teeth dental problems 1.3 2.1 4.3 -1.4 -1.7 -2.1 -1.6 -1.4 -0.8 -1.2 -1.1 -1.3 -1.3 -0.8 -1.2 -1.4 -1.6 -1.5 -1.4 -0.9 -1.9 -1.4 -1.3 1.4 -1.4 -1.6 -1.8 -1.2 -2.0 -1.1 -1.2 -1.8 -1.5 -1.0 -1.6 -1.6 -1.0
Heart attack 0.1 0.1 0.3 -0.2 -0.6 -0.5 -0.1 -0.1 0.0 -0.4 -0.5 -0.2 -0.4 0.1 0.2 -0.1 -0.1 -0.3 -0.2 -0.2 -0.5 -0.1 -0.3 0.4 -0.5 -0.2 -0.0 -0.4 -0.1 -0.5 -0.3 0.5 -0.3 -0.3 -0.1 -0.0 -0.5
Allergy 0.4 0.9 4.9 0.6 0.7 0.6 0.8 0.7 2.2 0.6 0.9 0.8 0.9 1.8 -0.3 0.6 0.7 0.7 0.6 1.5 0.1 0.9 1.0 -0.5 1.1 0.8 0.1 0.6 0.5 1.6 0.5 -0.2 0.9 0.8 0.7 0.7 1.3
Pain all over the body in last month 0.2 0.2 1.6 -0.2 0.5 -0.3 0.1 0.0 0.5 -0.3 -0.2 -0.1 0.2 -0.9 -1.3 0.0 0.2 0.0 -0.1 0.7 -1.2 0.3 -0.3 -0.0 0.2 0.2 -0.9 -0.3 0.4 0.3 -0.4 0.4 0.2 0.8 0.2 0.2 -0.8
Diabetes (self-reported) 0.5 0.7 1.7 0.8 1.3 0.8 0.8 0.9 1.1 0.8 1.0 0.9 0.8 0.8 0.5 1.0 0.9 0.9 0.9 1.1 1.2 0.8 0.5 -0.9 0.8 0.8 0.9 0.8 0.8 0.8 0.5 0.5 0.8 0.9 0.9 0.9 0.5
Hayfever/allergic rhinitis (self-reported) 0.6 0.9 1.8 -0.8 -0.7 -0.9 -0.9 -1.0 -1.1 -0.9 -0.8 -1.1 -1.2 -0.3 0.2 -0.9 -1.0 -0.9 -1.0 -0.9 -0.8 -1.0 -1.0 0.9 -1.1 -0.4 -0.5 -0.9 -0.7 -1.3 -1.3 -0.3 -1.1 -1.4 -1.0 -1.0 -0.9
Medication: Ramipril 1.2 1.5 3.3 -1.2 -1.3 -1.3 -1.2 -1.3 0.1 -1.3 -1.1 -1.2 -1.0 -1.1 -1.3 -1.2 -1.3 -1.3 -1.4 -0.9 -1.7 -1.4 -1.2 1.4 -1.8 -0.8 -0.6 -1.3 -1.1 -1.5 -1.8 -0.9 -1.4 -1.0 -1.3 -1.3 -1.1
Medication: Simvastatin 0.4 0.6 2.7 -0.6 0.2 -0.7 -0.7 -0.6 -1.5 -0.4 -0.8 -0.6 -1.3 0.0 -1.7 -0.7 -0.6 -0.6 -0.7 -0.9 -1.4 -0.8 -0.5 0.8 -0.5 -0.6 0.1 -0.5 0.7 -1.0 0.1 0.6 -0.9 -0.6 -0.6 -0.6 -0.2
Fluid intelligence score 0.1 0.3 5.2 0.0 0.5 -0.2 -0.3 -0.1 -0.7 -0.3 -0.1 -0.2 -0.8 -2.3 -0.9 -0.1 -0.1 -0.2 -0.2 -0.0 -0.0 0.0 -0.2 0.2 0.2 -0.4 -0.7 -0.3 -0.7 0.2 0.2 -0.5 -0.3 -0.4 -0.1 -0.1 -0.6
Illnesses of siblings 0.8 1.1 3.2 1.0 0.4 0.7 1.0 0.9 0.5 1.2 1.6 1.0 1.2 1.6 1.8 0.9 0.9 1.0 1.0 0.7 1.4 0.9 1.0 -1.0 0.5 0.8 0.4 1.1 0.0 1.8 1.2 -1.0 1.1 -0.6 0.9 0.9 0.8
Neuroticism score 0.2 0.4 2.4 0.7 0.9 0.5 0.3 0.6 1.3 0.7 0.4 0.6 0.4 0.4 0.3 0.7 0.5 0.4 0.5 0.0 0.5 0.5 0.3 -0.5 0.7 -0.2 -0.1 0.7 -0.1 0.9 1.5 -0.2 0.6 0.2 0.5 0.5 0.7
Weight 0.1 0.4 4.2 0.4 0.8 0.5 0.1 0.3 -0.4 0.3 -0.1 0.3 0.2 -0.9 0.4 0.4 0.3 0.1 0.3 -0.1 0.5 0.1 -0.1 -0.2 0.4 0.3 0.1 0.3 1.3 -0.5 -0.2 2.0 0.2 1.5 0.3 0.3 -0.4
Impedance of arm (right) 0.1 0.5 3.5 0.2 -0.5 0.6 0.2 -0.0 -1.5 0.3 0.7 0.1 -0.4 0.6 0.8 -0.2 -0.1 0.0 0.1 -0.8 -0.6 -0.1 0.6 0.2 -1.0 1.1 1.4 0.2 0.2 -0.5 -0.8 -0.0 -0.2 -1.9 -0.1 -0.1 0.8
Arm fat percentage (right) 0.3 1.0 4.8 1.1 1.3 1.3 0.8 1.0 -0.5 1.2 1.0 1.0 0.7 1.1 1.1 1.1 0.8 0.8 1.0 0.2 0.1 0.6 0.8 -0.9 1.0 1.2 0.8 1.2 1.7 0.6 0.7 2.2 0.8 1.0 0.8 0.8 0.2
Trunk fat-free mass 0.1 0.4 4.5 -0.1 -0.4 -0.7 -0.4 -0.3 0.5 -0.3 -0.7 -0.2 0.0 -2.1 -0.2 -0.2 -0.3 -0.3 -0.3 0.4 0.5 -0.3 -0.8 0.3 -0.1 -0.7 -0.6 -0.2 0.2 -1.0 -0.8 1.1 -0.3 1.7 -0.3 -0.3 -0.5
Hip circumference 0.1 0.3 2.9 0.4 1.1 0.6 0.0 0.1 0.5 0.3 0.0 0.3 0.0 -0.9 0.6 0.4 0.2 0.0 0.2 -0.5 0.1 0.1 0.1 -0.2 0.5 0.5 -0.2 0.3 1.1 -0.1 -0.2 1.1 0.2 1.7 0.2 0.2 -0.2
Time employed in main current job 0.3 0.4 2.2 -0.3 0.3 -0.3 -0.8 -0.4 0.4 -0.3 -0.4 -0.5 -0.5 -1.1 -1.5 -0.6 -0.7 -0.6 -0.5 0.5 -0.6 -0.5 -0.4 0.5 -0.2 -0.7 -1.1 -0.3 -0.4 0.2 -0.5 -0.9 -0.4 0.9 -0.7 -0.7 0.1
Alcohol intake versus 10 years previously 0.1 0.1 1.1 -0.4 -0.9 0.0 -0.2 -0.2 -0.5 -0.2 -0.4 -0.2 -0.4 1.1 -0.2 -0.3 -0.3 -0.2 -0.2 -0.3 -0.2 -0.4 -0.1 0.3 -0.2 -0.4 0.0 -0.2 0.1 -0.6 -0.3 0.6 -0.4 -0.4 -0.3 -0.3 -0.3
Father’s age at death 0.8 1.0 3.2 -1.0 -0.4 -1.4 -1.0 -1.0 1.2 -1.1 -0.8 -1.0 -0.8 -1.8 -0.5 -1.0 -1.0 -0.9 -1.0 -0.3 -0.6 -0.8 -1.1 1.1 -0.4 -1.0 -1.4 -1.1 -1.5 -0.6 -1.4 -1.2 -0.9 0.1 -1.0 -1.0 -1.1
Worrier / anxious feelings 0.1 0.1 1.4 0.1 0.4 0.1 0.2 0.2 1.2 0.1 -0.1 0.1 0.4 0.1 -0.0 0.4 0.2 0.1 0.1 0.3 0.1 0.2 0.3 -0.1 0.3 -0.2 -0.4 0.1 -0.2 0.1 0.5 0.1 0.3 0.3 0.2 0.2 0.3
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.8 -0.6 -0.9 -0.4 -0.8 -0.7 -0.9 -0.6 -0.6 -0.6 -0.4 -1.0 -0.4 -0.7 -0.8 -0.7 -0.7 -1.1 -1.2 -1.0 -0.7 0.5 -0.9 -0.3 -0.5 -0.6 -0.7 -1.0 -1.0 -0.0 -0.9 -0.1 -0.8 -0.8 -1.3
Falls in the last year 0.2 0.3 2.4 0.4 0.8 0.6 0.3 0.4 -1.5 0.3 0.1 0.4 -0.0 -0.0 -0.1 0.4 0.5 0.4 0.3 0.8 -0.2 0.4 -0.2 -0.5 0.8 0.0 -0.0 0.2 0.1 0.3 1.0 0.5 0.2 -0.5 0.5 0.5 -0.4
Hair/balding pattern: Pattern 3 5.7 8.5 12.0 -2.9 -3.1 -3.2 -3.0 -3.0 -0.6 -2.9 -2.3 -3.2 -2.9 -2.4 -3.2 -3.1 -3.1 -3.1 -3.1 -2.2 -3.0 -3.1 -2.7 3.4 -3.5 -2.3 -2.5 -3.0 -2.9 -2.9 -3.4 -3.1 -3.1 -2.6 -3.1 -3.1 -2.6
Number of live births 0.9 1.3 3.1 -1.2 -0.8 -1.0 -1.2 -1.2 -0.9 -1.2 -1.6 -1.3 -1.3 -1.2 -1.4 -1.0 -1.1 -1.2 -1.2 -1.8 -0.9 -1.3 -1.1 0.9 -0.9 -1.3 -1.2 -1.2 -0.7 -1.4 -0.8 -0.9 -1.3 -0.4 -1.1 -1.1 -1.2
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 2.8 0.9 -0.1 0.5 0.8 0.7 1.5 0.7 0.5 0.8 1.1 -0.4 0.6 0.8 0.7 0.8 0.7 1.4 1.4 0.7 0.5 -0.6 0.5 0.7 1.0 0.6 0.9 0.1 0.1 1.4 0.9 1.7 0.7 0.7 0.8
Pulse rate 0.2 0.4 1.1 0.2 0.9 0.4 0.7 0.7 0.4 0.2 -0.0 0.5 0.6 0.4 0.3 0.7 0.8 0.6 0.5 1.0 1.0 1.0 0.5 -0.4 0.6 -0.1 -0.6 0.2 0.8 0.6 0.6 -0.4 0.7 1.0 0.8 0.8 0.5
Happiness 0.3 0.3 2.9 0.3 0.3 0.6 0.2 0.3 -0.1 0.4 -0.1 0.4 0.2 0.0 1.0 0.3 0.4 0.3 0.3 -0.3 0.5 0.4 0.1 -0.5 0.5 0.4 0.2 0.4 1.0 0.0 0.6 1.5 0.5 1.7 0.4 0.4 0.6
Noisy workplace 0.1 0.2 0.6 -0.6 -0.0 -0.4 -0.4 -0.3 0.7 -0.6 -0.8 -0.4 -0.4 0.3 -0.6 -0.4 -0.3 -0.3 -0.5 0.6 0.4 -0.3 -0.3 0.5 -0.3 0.0 -0.4 -0.6 0.3 0.0 0.1 -0.1 -0.2 0.6 -0.3 -0.3 -0.2
Qualifications: A levels/AS levels or equivalent 0.2 0.4 2.5 -0.8 -1.2 0.0 0.4 -0.2 0.4 -0.8 -0.6 -0.2 0.3 -1.4 -0.1 -0.2 0.2 0.1 -0.2 -0.7 -0.3 0.3 -0.1 0.3 -0.2 -0.7 -0.3 -0.8 -1.6 -0.6 -0.1 -0.8 -0.0 -0.7 0.2 0.2 -0.6
Serious illness, injury or assault of a close relative in last 2 years 1.9 2.2 5.1 -1.2 -2.3 -1.2 -1.3 -1.5 -1.2 -1.4 -1.5 -1.5 -1.4 -1.4 -1.3 -1.6 -1.5 -1.3 -1.4 -1.3 -1.1 -1.5 -1.5 1.6 -1.8 -1.9 -1.1 -1.4 -1.5 -2.0 -1.4 -1.3 -1.7 -1.9 -1.5 -1.5 -1.3
Mouth/teeth dental problems: Dentures 1.7 2.8 7.5 2.0 2.7 2.3 1.4 1.7 0.7 1.9 1.5 1.7 0.9 1.2 0.4 1.4 1.5 1.6 1.7 1.4 1.9 1.5 1.6 -1.7 1.9 1.5 1.6 1.9 2.6 1.4 1.8 2.1 1.5 1.6 1.5 1.5 1.5
Asthma 0.7 1.5 6.2 -1.1 -0.4 -1.0 -1.0 -1.1 -1.6 -1.2 -1.2 -1.2 -1.4 -1.7 0.8 -1.0 -0.9 -1.1 -1.1 -2.2 -0.4 -1.1 -0.9 0.9 -1.6 -1.1 -0.4 -1.2 -0.7 -1.4 -0.5 -1.1 -1.3 -2.5 -0.9 -0.9 -1.4
Medication: Ibuprofen (e.g. Nurofen) 0.1 0.2 0.7 -0.1 0.2 -0.1 -0.1 -0.2 0.5 -0.3 -0.3 -0.3 -0.3 -0.8 -0.5 -0.1 -0.1 -0.2 -0.2 -0.8 -0.8 -0.1 -0.2 0.3 -0.2 0.0 -0.2 -0.3 -0.1 -0.5 -0.8 -0.8 -0.3 -0.2 -0.1 -0.1 0.2
Medication: Cholesterol lowering 0.1 0.1 0.9 0.2 0.8 0.4 0.2 0.3 -0.8 0.3 0.4 0.2 0.0 -0.3 0.1 0.2 0.3 0.1 0.2 -0.1 -1.0 0.2 0.5 -0.2 0.2 0.0 0.4 0.3 0.4 0.2 0.4 0.2 0.2 0.1 0.3 0.3 0.4
Depression (self-reported) 0.8 1.0 3.9 1.1 1.1 0.7 0.6 0.8 1.6 1.1 0.7 1.0 0.7 0.7 0.6 0.8 0.7 0.7 0.8 0.9 0.2 0.7 0.7 -0.8 1.3 0.4 0.6 1.1 1.3 0.9 1.3 2.0 1.0 1.9 0.7 0.7 1.0
Medication: Lansoprazole 0.5 0.6 2.6 0.6 0.7 0.6 0.8 0.9 -0.2 0.7 0.9 0.7 0.8 1.6 0.0 0.8 0.8 0.8 0.8 0.4 1.2 0.8 0.6 -0.8 1.1 0.7 0.2 0.7 0.5 0.9 0.8 0.2 0.6 -0.3 0.8 0.8 0.3
Prospective memory result 0.1 0.2 1.6 -0.4 0.6 -0.2 -0.1 -0.1 -0.2 -0.2 -0.7 -0.1 0.3 1.3 -1.1 -0.2 -0.1 -0.0 -0.1 -0.5 -0.5 0.1 -0.2 0.1 0.3 -0.7 -0.6 -0.2 -0.3 -0.3 0.2 0.3 -0.1 0.6 -0.1 -0.1 -0.2
Lung cancer (father) 0.3 0.3 2.0 0.4 -0.3 0.2 0.2 0.2 0.9 0.4 0.3 0.3 0.4 1.4 -0.0 0.2 0.1 0.3 0.3 0.1 -0.4 0.1 0.3 -0.4 0.4 0.8 0.8 0.4 1.1 0.0 -0.1 1.4 0.4 1.4 0.1 0.1 0.6
Illnesses of mother 0.2 0.3 1.2 -0.2 -0.0 -0.2 -0.7 -0.4 -0.6 -0.1 0.1 -0.3 -0.5 0.4 -0.6 -0.5 -0.6 -0.5 -0.4 -0.6 -0.9 -0.5 -0.4 0.2 -0.3 -0.5 -0.7 -0.1 -0.9 0.1 -0.3 -1.1 -0.5 -0.7 -0.6 -0.6 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.4 1.8 0.7 -0.8 0.3 0.6 0.4 1.3 0.4 0.3 0.5 0.6 -0.7 0.4 0.6 0.5 0.5 0.5 0.6 1.3 0.5 0.2 -0.3 -0.1 0.6 0.9 0.4 0.9 -0.5 -0.5 0.9 0.5 1.3 0.5 0.5 0.9
Pulse wave Arterial Stiffness index 0.2 0.2 1.3 -0.4 0.0 -0.4 -0.3 -0.3 0.2 -0.5 -1.0 -0.4 -0.5 -0.7 -0.8 -0.3 -0.3 -0.3 -0.4 -0.1 0.4 -0.4 -0.5 0.5 -0.2 -1.2 -0.3 -0.5 -0.4 -0.7 0.8 -0.0 -0.4 -0.4 -0.3 -0.3 -0.5
Impedance of arm (left) 0.2 0.8 3.6 0.9 0.2 1.3 0.9 0.6 -0.8 0.9 1.2 0.7 0.3 1.2 1.4 0.6 0.6 0.7 0.8 -0.4 0.3 0.6 1.5 -0.5 -0.2 1.6 1.9 0.9 0.8 0.1 0.1 0.6 0.5 -1.0 0.6 0.6 1.4
Arm fat mass (right) 0.2 0.9 5.0 1.0 1.4 1.2 0.7 0.9 -0.3 1.1 0.8 0.9 0.7 0.3 0.9 1.0 0.8 0.8 0.9 0.3 0.5 0.6 0.6 -0.9 1.1 1.0 0.6 1.1 1.7 0.4 0.5 2.2 0.8 1.4 0.8 0.8 0.1
Trunk predicted mass 0.1 0.4 4.3 -0.1 -0.4 -0.7 -0.4 -0.3 0.5 -0.3 -0.7 -0.2 0.0 -2.1 -0.2 -0.2 -0.3 -0.3 -0.3 0.4 0.5 -0.3 -0.8 0.3 -0.1 -0.7 -0.7 -0.3 0.2 -0.9 -0.8 1.0 -0.3 1.7 -0.3 -0.3 -0.6
Standing height 0.2 1.6 7.9 -1.0 -1.5 -1.2 -1.0 -1.1 -1.0 -1.2 -1.5 -1.1 -1.0 -2.8 -0.5 -1.2 -1.1 -1.1 -1.1 -0.8 0.3 -1.0 -1.2 1.4 -1.8 -1.0 -0.6 -1.2 -0.5 -2.5 -2.4 0.1 -1.3 0.0 -1.1 -1.1 -0.7
Length of working week for main job 0.6 0.7 1.6 1.2 0.1 1.1 0.7 0.9 -0.0 1.2 1.1 1.0 0.4 0.9 0.7 0.7 0.7 0.9 1.0 0.6 0.5 0.6 0.8 -1.0 0.6 0.8 1.0 1.2 1.0 0.6 0.6 1.2 0.6 0.1 0.7 0.7 0.6
Exposure to tobacco smoke at home 0.1 0.1 1.5 0.0 0.3 0.3 0.1 0.3 -0.4 0.1 -0.1 0.2 0.1 -0.1 0.3 0.4 0.3 0.1 0.1 0.3 0.5 0.1 -0.0 0.0 0.1 -0.0 0.2 0.1 0.4 -0.2 0.6 1.2 0.2 0.0 0.3 0.3 -0.4
Breastfed as a baby 0.1 0.1 1.2 0.3 -0.6 -0.1 -0.1 -0.0 0.3 0.2 0.3 -0.0 0.1 -0.9 0.1 -0.1 -0.2 -0.0 0.0 -0.5 0.9 -0.0 -0.0 -0.2 -0.2 0.2 -0.4 0.2 0.1 -0.1 -1.1 -0.6 -0.1 0.3 -0.2 -0.2 0.3
Tense / ‘highly strung’ 0.0 0.1 0.4 -0.2 -0.0 -0.2 -0.4 -0.2 -0.5 -0.1 -0.1 -0.2 -0.3 -0.1 -0.2 -0.3 -0.3 -0.3 -0.3 -0.1 -0.1 -0.2 -0.5 0.1 -0.5 -0.1 -0.4 -0.1 0.1 0.1 -0.0 -0.6 -0.2 -0.6 -0.3 -0.3 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.6 6.4 -1.0 -0.7 -1.6 -1.5 -1.4 -0.6 -1.1 -1.0 -1.3 -1.1 -0.9 -0.1 -1.3 -1.4 -1.4 -1.3 -2.5 -1.6 -1.4 -1.1 1.2 -1.1 -1.0 -1.4 -1.1 -1.1 -0.8 -1.2 -1.0 -1.3 -0.8 -1.4 -1.4 -1.6
Hair/balding pattern: Pattern 4 0.3 0.8 5.1 -1.0 -0.5 -1.2 -0.7 -1.0 -0.2 -1.2 -0.9 -1.1 -1.0 0.0 -0.2 -0.9 -0.9 -0.9 -0.9 -0.4 -0.8 -1.0 -0.7 1.0 -1.3 0.3 -0.3 -1.2 -0.3 -1.3 -2.3 -0.0 -1.1 -0.0 -0.9 -1.0 -0.9
Birth weight of first child 0.2 0.3 3.4 -0.3 -0.2 -0.3 -0.2 -0.1 -0.9 -0.3 -0.1 -0.4 -0.5 -0.6 -0.1 -0.2 -0.2 -0.1 -0.2 0.2 0.4 -0.1 -0.1 0.5 -0.4 -0.7 -0.6 -0.3 -0.8 -0.0 0.1 -1.9 -0.4 -1.7 -0.2 -0.2 -0.4
Peak expiratory flow (PEF) 0.5 1.1 2.8 -1.2 -1.4 -1.5 -0.9 -1.1 0.1 -1.3 -1.6 -1.1 -0.8 -1.4 -0.6 -1.0 -1.0 -1.1 -1.2 0.1 -0.4 -1.1 -1.2 1.4 -1.3 -0.8 -0.3 -1.4 -0.4 -1.7 -1.3 0.1 -0.9 0.4 -1.0 -1.0 -0.7
Pulse wave reflection index 0.3 0.4 1.6 0.6 0.7 0.5 0.7 0.6 0.8 0.6 0.2 0.7 0.6 0.1 0.5 0.6 0.7 0.7 0.7 -0.1 0.7 0.6 0.6 -0.8 0.8 0.2 0.7 0.6 -0.0 0.3 1.2 1.1 0.7 0.1 0.7 0.7 0.4
Ever highly irritable/argumentative for 2 days 0.6 0.7 3.6 -0.5 -0.9 -0.7 -0.7 -0.7 -1.2 -0.5 -0.9 -0.5 -1.1 0.3 -1.1 -0.5 -0.7 -0.7 -0.6 -1.9 -0.6 -0.9 -0.7 0.7 -1.3 -0.4 0.2 -0.5 0.5 -1.3 -0.2 0.9 -0.8 -0.9 -0.7 -0.6 -0.7
Loud music exposure frequency 0.4 0.5 3.0 -0.6 -0.4 -0.3 -0.6 -0.6 -1.5 -0.5 -0.7 -0.6 -0.7 -1.0 -0.3 -0.6 -0.6 -0.6 -0.5 -1.7 -0.6 -0.5 -0.4 0.5 -0.5 -0.8 -0.8 -0.5 -0.6 -0.6 -0.3 0.0 -0.6 -0.3 -0.6 -0.6 -1.1
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 4.3 -1.0 -1.3 -0.7 -0.4 -0.7 -0.6 -1.0 -0.9 -0.8 -0.6 -2.1 -0.1 -0.7 -0.6 -0.6 -0.7 -0.5 -0.2 -0.5 -0.5 0.9 -0.8 -1.4 -0.9 -1.0 -2.1 -0.9 -0.6 -1.3 -0.7 -1.5 -0.6 -0.6 -0.7
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 1.5 0.4 0.4 1.0 0.7 0.7 1.1 0.3 0.3 0.6 0.6 -0.2 0.8 0.8 0.8 0.7 0.5 0.7 0.5 0.8 0.6 -0.6 0.8 0.5 0.6 0.3 0.4 1.0 1.2 -0.0 0.8 0.2 0.8 0.8 0.5
Blood clot in the leg (DVT) 0.6 0.8 2.0 -1.1 0.3 -0.9 -0.9 -1.0 -1.0 -1.1 -1.0 -1.0 -0.5 0.5 -0.5 -0.8 -0.8 -0.9 -1.0 -1.4 -1.1 -0.8 -1.0 0.6 -0.6 -0.7 -1.1 -1.0 -0.8 -0.2 -0.4 -1.4 -0.7 -0.5 -0.8 -0.8 -1.1
Medication: Paracetamol 0.2 0.3 2.4 1.0 0.5 0.9 0.3 0.5 -1.5 0.8 0.8 0.4 0.4 -0.1 0.6 0.4 0.3 0.4 0.6 0.1 -0.6 0.2 0.3 -0.7 0.2 0.2 0.3 0.8 0.1 0.1 0.2 0.3 0.4 -0.2 0.3 0.3 0.0
Headache pain in last month 1.7 2.8 5.9 -1.3 -1.5 -1.1 -1.7 -1.7 -2.1 -1.4 -1.8 -1.6 -1.9 -2.3 -1.2 -1.7 -1.9 -1.7 -1.5 -2.2 -2.4 -1.8 -1.9 1.8 -1.8 -1.5 -0.9 -1.4 -1.4 -2.4 -1.7 -0.3 -1.8 -1.0 -1.9 -1.9 -1.0
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 2.3 -0.9 -1.3 -0.8 -0.7 -0.8 0.2 -0.9 -0.9 -0.8 -0.5 -0.7 -0.4 -0.7 -0.8 -0.7 -0.8 -0.5 0.1 -0.8 -0.9 0.8 -0.9 -1.0 -1.0 -0.9 -1.4 -0.7 -0.5 -1.3 -0.8 -1.5 -0.8 -0.8 -0.9
Glaucoma (self-reported) 4.4 5.1 7.3 2.2 2.2 2.7 2.4 2.3 1.0 2.1 2.3 2.3 2.6 2.0 2.3 2.5 2.4 2.3 2.3 2.1 2.0 2.2 2.1 -2.4 2.5 2.5 2.3 2.1 2.4 1.9 1.7 2.7 2.5 2.4 2.4 2.4 2.0
Gout (self-reported) 0.5 0.6 2.8 -0.5 -0.3 -1.0 -0.7 -0.7 0.3 -0.7 -0.3 -0.7 -0.7 -1.0 -1.7 -0.6 -0.7 -0.7 -0.7 -0.8 -1.1 -0.5 -0.8 0.7 -0.7 -0.5 -1.3 -0.6 -1.0 -0.1 -0.8 -1.6 -0.6 -0.6 -0.7 -0.7 -0.6
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 2.4 1.2 1.2 0.9 1.1 1.1 0.8 1.2 1.2 1.0 1.0 1.1 0.7 1.1 1.0 1.2 1.2 0.8 1.1 1.2 1.3 -1.2 0.9 1.4 0.7 1.2 1.3 1.1 0.4 0.5 1.1 1.1 1.0 1.0 1.6
Medication: Amlodipine 1.0 1.4 5.7 -1.3 -0.4 -1.2 -1.2 -1.1 -2.4 -1.2 -1.3 -1.1 -1.1 -1.3 -1.2 -1.4 -1.1 -1.2 -1.2 -0.6 -1.5 -1.1 -1.3 1.1 -1.1 -1.0 -1.0 -1.2 -1.1 -1.2 -0.9 -0.1 -1.2 -0.2 -1.1 -1.1 -1.4
Medication: Ventolin 100micrograms inhaler 0.1 0.2 1.3 -0.2 -0.1 0.6 0.3 -0.0 -0.6 -0.2 -0.1 -0.1 0.2 -0.7 1.1 -0.0 0.1 -0.0 -0.0 -0.3 1.1 -0.1 0.2 -0.0 -0.4 0.0 0.6 -0.2 -0.0 -0.6 -0.1 0.1 0.0 -0.8 0.1 0.1 -0.1
Birth weight 0.1 0.2 1.0 -0.3 -0.8 -0.7 -0.3 -0.4 -1.0 -0.2 -0.2 -0.4 -0.4 -0.7 -0.4 -0.3 -0.5 -0.4 -0.3 -0.4 0.5 -0.3 -0.3 0.4 -0.7 -0.5 -0.4 -0.2 -0.4 -0.8 -0.8 0.1 -0.5 -0.5 -0.5 -0.5 -0.2
Chronic bronchitis/emphysema (mother) 0.6 0.7 2.8 0.4 0.0 0.2 0.8 0.8 -0.7 0.5 0.0 0.9 0.7 1.3 0.6 0.9 0.9 0.8 0.7 1.2 1.5 0.7 0.6 -0.7 1.0 0.6 1.1 0.5 1.3 0.4 1.0 1.7 0.7 1.1 0.9 0.9 0.5
High blood pressure (siblings) 0.1 0.2 0.7 -0.4 0.1 -0.4 -0.2 -0.2 -0.9 -0.4 -0.8 -0.3 -0.2 -0.3 -0.8 -0.2 -0.1 -0.2 -0.2 -0.2 -0.5 -0.0 -0.3 0.2 0.3 -0.6 -0.5 -0.4 -0.1 -0.6 -0.2 0.7 -0.2 0.9 -0.1 -0.1 -0.4
Forced vital capacity (FVC), Best measure 0.4 1.4 5.4 1.4 0.2 1.0 1.3 1.2 1.5 1.1 1.0 1.2 1.3 -0.7 1.3 1.4 1.3 1.3 1.2 1.3 2.3 1.4 0.9 -1.0 0.6 1.1 1.2 1.1 1.2 0.4 0.4 0.9 1.2 1.3 1.3 1.3 1.5
Body fat percentage 0.2 0.9 4.0 0.9 1.4 1.3 0.8 0.9 -0.8 1.0 0.8 0.9 0.5 0.8 1.3 1.0 0.9 0.7 0.9 0.1 0.5 0.7 0.9 -0.8 0.9 1.3 0.8 1.0 1.8 0.5 0.6 2.0 0.8 0.8 0.9 0.9 0.3
Leg fat percentage (right) 0.1 0.5 2.3 0.5 1.2 0.7 0.6 0.6 -0.1 0.5 0.5 0.6 0.4 0.5 1.0 0.7 0.6 0.4 0.5 0.5 0.4 0.5 0.5 -0.5 0.7 0.9 0.3 0.5 1.5 0.7 0.5 1.3 0.6 0.7 0.6 0.6 0.1
Arm fat-free mass (right) 0.1 0.4 3.3 -0.2 0.1 -0.5 -0.4 -0.2 0.4 -0.3 -0.9 -0.2 -0.0 -1.8 -0.4 -0.1 -0.2 -0.2 -0.2 0.1 0.5 -0.3 -0.8 0.2 0.2 -0.8 -0.7 -0.3 0.4 -0.8 -0.3 1.4 -0.2 1.8 -0.2 -0.2 -0.7
Exposure to tobacco smoke outside home 1.5 2.0 5.9 1.7 0.8 1.6 1.2 1.5 2.4 1.7 1.1 1.5 1.1 -0.1 1.4 1.4 1.4 1.4 1.5 1.4 1.3 1.5 1.1 -1.1 1.5 0.9 0.9 1.7 1.2 1.0 1.7 1.5 1.4 1.8 1.4 1.4 1.8
Comparative body size at age 10 0.3 0.9 2.6 1.1 -0.4 1.2 0.9 0.8 0.8 1.0 1.2 0.9 1.2 0.3 1.6 0.7 0.7 0.8 1.0 1.0 1.3 0.6 0.8 -0.9 0.1 1.2 1.3 1.0 1.0 0.1 -0.3 1.3 0.9 1.1 0.7 0.7 0.7
Number of full brothers 0.2 0.2 1.2 -0.3 0.3 -0.1 -0.5 -0.5 -0.6 -0.4 -0.2 -0.4 -0.4 -0.7 -1.1 -0.3 -0.4 -0.4 -0.5 -0.5 -0.6 -0.4 -0.6 0.2 0.3 -0.4 -0.6 -0.4 -0.1 0.6 0.0 -0.9 -0.3 -0.1 -0.4 -0.4 -0.4
Worry too long after embarrassment 0.4 0.7 3.0 0.5 1.1 0.8 0.9 0.9 0.3 0.6 0.6 0.9 1.1 0.1 1.0 0.8 1.0 0.9 0.7 1.5 0.6 1.0 0.6 -0.9 1.1 0.1 0.2 0.6 -0.1 1.3 1.7 0.3 1.0 0.1 1.0 1.0 0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 2.6 0.4 0.1 0.0 0.4 0.4 -0.0 0.4 0.4 0.5 0.6 1.3 1.6 0.5 0.5 0.5 0.5 -0.4 0.5 0.3 0.4 -0.6 0.5 0.8 1.1 0.4 0.9 0.5 0.7 0.5 0.5 0.2 0.5 0.5 0.4
Wheeze or whistling in the chest in last year 0.2 0.3 2.5 -0.5 0.6 -0.5 -0.2 -0.2 -1.5 -0.6 -0.6 -0.4 -0.5 0.3 0.2 -0.2 -0.1 -0.3 -0.5 0.2 0.4 -0.3 -0.2 0.2 -0.2 0.2 0.1 -0.6 0.8 0.0 0.4 0.2 -0.4 -1.6 -0.1 -0.1 -0.7
Number of children fathered 0.2 0.2 1.1 -0.2 -0.5 -0.1 -0.2 -0.3 -0.7 -0.1 -0.4 -0.3 -0.1 -1.0 0.3 -0.2 -0.3 -0.3 -0.1 -0.4 -1.1 -0.2 -0.4 0.2 -0.6 -0.4 -0.1 -0.1 -0.4 -0.9 -0.9 0.1 -0.1 0.5 -0.3 -0.3 -0.2
Reason for reducing amount of alcohol drunk: Health precaution 6.4 7.5 14.9 -2.8 -2.7 -2.6 -2.9 -3.3 -0.3 -3.1 -2.6 -3.2 -2.7 -2.0 -1.1 -3.1 -3.2 -3.2 -3.1 -2.8 -2.5 -3.1 -2.2 3.1 -3.5 -1.5 -2.0 -3.1 -2.8 -2.8 -3.9 -2.2 -3.0 -1.6 -3.2 -3.2 -2.2
Age at first live birth 0.3 0.6 2.1 0.5 -0.5 0.6 0.9 0.5 0.2 0.4 0.8 0.6 1.4 0.1 0.0 0.7 0.6 0.6 0.6 0.9 0.8 0.7 0.6 -0.6 0.2 0.9 1.1 0.5 0.4 0.2 -0.8 1.1 0.9 1.4 0.6 0.6 1.4
Pulse wave peak to peak time 0.2 0.2 1.4 0.4 -0.1 0.4 0.3 0.2 -0.3 0.4 0.9 0.3 0.4 0.5 0.8 0.2 0.2 0.2 0.3 -0.0 -0.5 0.3 0.4 -0.4 0.2 1.2 0.3 0.4 0.5 0.5 -0.9 0.2 0.3 0.4 0.2 0.2 0.4
Health satisfaction 0.1 0.1 0.7 -0.5 -0.5 -0.3 -0.1 -0.2 0.2 -0.4 -0.8 -0.3 0.2 0.2 0.3 -0.2 -0.1 -0.2 -0.3 -0.6 -0.3 -0.2 -0.3 0.3 -0.1 -0.4 -0.3 -0.5 0.1 -0.6 -0.1 0.7 -0.2 0.5 -0.1 -0.1 -0.5
Shortness of breath walking on level ground 0.7 0.8 2.5 -1.5 -0.3 -0.9 -0.7 -1.0 -1.5 -1.5 -1.1 -1.0 -0.7 -0.5 0.6 -1.0 -0.7 -0.9 -1.1 -0.2 0.1 -0.9 -0.9 0.8 -0.7 -0.1 -0.4 -1.4 -0.3 -0.6 -1.2 -0.5 -1.1 -0.9 -0.7 -0.7 -1.6
Qualifications: College or University degree 2.1 6.5 13.2 -2.5 -3.6 -2.2 -2.2 -2.6 -0.2 -2.6 -2.2 -2.5 -2.4 -3.6 -2.5 -2.6 -2.4 -2.4 -2.6 -2.7 -3.0 -2.5 -2.4 2.7 -3.0 -2.3 -1.5 -2.6 -2.7 -2.9 -2.9 -2.2 -2.7 -2.7 -2.4 -2.4 -2.0
Eye problems/disorders: None of the above 0.6 0.7 2.5 -0.3 -1.0 -0.9 -1.0 -0.8 -0.6 -0.4 -0.6 -0.7 -0.9 -0.2 -0.7 -0.8 -1.0 -0.8 -0.7 -1.6 -1.1 -0.9 -0.8 0.5 -0.7 -1.1 -0.9 -0.4 -1.0 -0.5 -0.4 -0.8 -0.9 -0.7 -1.0 -1.0 -0.7
Mouth/teeth dental problems: Loose teeth 0.1 0.1 1.5 0.0 0.2 0.6 -0.1 -0.0 0.8 -0.0 -0.1 -0.1 -0.0 -0.2 -0.0 -0.1 -0.2 -0.2 -0.0 1.2 -0.4 -0.1 0.0 0.1 0.3 -0.3 -0.2 -0.0 -0.5 0.2 0.1 -0.2 -0.1 0.5 -0.2 -0.2 0.0
Emphysema/chronic bronchitis 0.4 0.5 1.7 0.8 0.6 0.7 0.7 0.8 -0.3 0.8 0.7 0.6 0.6 0.8 -0.2 0.7 0.7 0.7 0.8 0.4 0.6 0.6 0.8 -0.7 0.5 1.0 0.2 0.7 1.3 0.2 -0.3 1.1 0.5 0.7 0.7 0.7 -0.0
Medication for pain relief, constipation, heartburn 0.7 1.1 3.6 1.2 0.2 0.6 1.0 1.1 0.7 1.2 1.1 1.2 0.8 1.5 0.7 1.1 1.0 1.1 1.2 1.4 1.7 1.1 0.9 -1.1 1.1 0.3 0.7 1.2 0.0 1.3 1.9 0.6 1.0 0.2 1.0 1.0 1.0
Neck or shoulder pain in last month 0.9 1.3 4.0 -1.1 -0.9 -1.4 -1.0 -1.2 -0.6 -1.1 -1.7 -1.0 -0.8 -1.6 -1.2 -1.2 -1.0 -1.0 -1.0 -2.0 -1.8 -1.1 -1.4 1.2 -0.9 -1.1 -0.6 -1.2 -0.8 -1.5 -0.8 -0.2 -1.3 -0.3 -1.0 -1.0 -0.9
Medication: Blood pressure 0.3 0.5 3.0 0.8 0.9 1.0 0.5 0.7 0.3 0.8 0.9 0.7 0.6 0.1 0.3 0.5 0.6 0.6 0.7 0.7 -0.2 0.7 0.6 -0.7 0.9 0.9 0.1 0.8 1.1 0.9 -0.1 0.5 0.7 1.7 0.6 0.6 0.7
Angina (self-reported) 0.3 0.4 5.3 -0.1 0.8 0.4 0.2 0.3 -2.3 0.2 0.2 0.3 -0.2 1.5 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.1 0.4 -0.1 0.4 0.3 0.6 0.2 0.4 0.5 1.0 0.6 0.1 -1.1 0.2 0.2 -0.0
Migraine (self-reported) 1.2 1.5 3.1 -1.4 -0.6 -1.5 -1.1 -1.1 -1.7 -1.3 -1.4 -1.1 -0.8 -1.3 -0.9 -1.4 -1.1 -1.1 -1.2 -1.4 -1.2 -1.2 -1.3 1.2 -1.5 -0.7 -0.4 -1.3 -0.7 -1.8 -1.3 -0.1 -1.2 -1.4 -1.1 -1.1 -1.3
Medication: Ibuprofen 0.3 0.4 1.6 0.6 0.6 0.6 0.8 0.5 1.3 0.5 0.6 0.6 0.5 -0.1 0.4 0.7 0.7 0.6 0.7 -0.3 0.1 0.6 0.7 -0.5 0.4 0.8 0.7 0.5 0.6 -0.0 -0.4 0.1 0.5 0.4 0.7 0.7 0.9
Medication: Allopurinol 0.4 0.5 3.2 -0.4 -0.0 -0.7 -0.6 -0.5 1.8 -0.4 -0.2 -0.5 -0.5 -1.0 -1.6 -0.5 -0.5 -0.5 -0.5 -0.3 -0.9 -0.3 -0.3 0.6 -0.3 -0.6 -1.3 -0.4 -0.9 -0.2 -0.8 -1.1 -0.3 0.6 -0.5 -0.5 -0.2
Medication: Omeprazole 0.2 0.2 1.6 -0.4 0.4 -0.2 -0.2 0.0 -0.0 -0.3 -0.5 -0.2 0.2 0.2 -0.8 -0.2 -0.0 -0.1 -0.2 1.3 0.7 -0.1 -0.3 0.3 0.4 -0.6 -0.6 -0.3 0.2 -0.2 0.1 0.7 -0.0 0.6 -0.0 -0.0 -0.8
Medication: Seretide 50 evohaler 0.3 0.3 0.8 -0.8 -0.5 -0.8 -0.5 -0.5 -0.7 -0.8 -0.7 -0.5 -0.6 0.5 -0.2 -0.6 -0.4 -0.4 -0.6 -0.5 0.0 -0.6 -0.3 0.5 -0.7 0.0 0.3 -0.8 0.1 -0.8 -0.5 0.0 -0.7 -0.9 -0.4 -0.4 -0.7
Mean time to correctly identify matches 0.1 0.3 1.2 0.5 0.2 0.4 0.4 0.4 -0.1 0.7 1.1 0.4 0.6 0.0 0.3 0.4 0.4 0.4 0.5 0.5 0.7 0.5 0.4 -0.8 0.7 0.7 -0.1 0.6 0.5 0.7 -0.3 0.5 0.6 0.9 0.4 0.4 0.3
Heart disease (mother) 0.4 0.5 1.2 0.7 0.7 0.8 0.8 0.7 0.6 0.6 0.7 0.6 0.4 0.1 0.2 0.9 0.8 0.7 0.6 0.0 0.7 0.8 0.6 -0.6 0.8 0.9 0.3 0.6 0.9 1.1 0.9 -0.2 0.6 -0.1 0.8 0.8 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 7.1 8.4 17.9 2.9 2.0 2.9 3.1 3.2 1.1 3.0 2.6 3.1 2.9 1.6 1.9 3.1 3.2 3.1 3.1 2.0 3.0 2.9 3.3 -3.0 2.9 3.3 3.3 3.0 4.1 2.0 2.4 4.2 3.0 2.6 3.2 3.2 2.4
Whole body fat mass 0.2 0.8 4.5 0.9 1.2 1.1 0.8 0.9 -0.7 0.9 0.6 0.8 0.6 0.3 1.1 1.0 0.8 0.7 0.8 0.3 0.7 0.7 0.7 -0.7 0.8 1.0 0.7 0.9 1.8 0.2 0.4 2.1 0.7 1.2 0.8 0.8 0.3
Leg fat mass (right) 0.1 0.4 2.5 0.5 1.1 0.6 0.5 0.6 -0.3 0.5 0.3 0.5 0.4 0.1 0.8 0.7 0.6 0.4 0.5 0.2 0.5 0.4 0.3 -0.5 0.7 0.6 0.2 0.5 1.4 0.3 0.4 1.6 0.5 1.1 0.6 0.6 -0.1
Arm predicted mass (right) 0.1 0.4 3.3 -0.3 0.1 -0.5 -0.3 -0.2 0.6 -0.3 -0.9 -0.2 0.1 -1.8 -0.3 -0.0 -0.1 -0.2 -0.2 0.2 0.6 -0.1 -0.8 0.2 0.3 -0.8 -0.8 -0.3 0.3 -0.7 -0.3 1.1 -0.1 1.8 -0.1 -0.1 -0.7
Pulse rate, automated reading 0.0 0.2 1.1 -0.4 0.1 -0.1 -0.2 -0.2 -0.1 -0.4 -1.0 -0.2 -0.4 0.3 0.0 -0.0 -0.1 -0.2 -0.3 -0.1 0.7 0.1 -0.3 0.5 -0.1 -0.9 -1.0 -0.4 0.4 -0.4 0.3 0.0 -0.2 0.5 -0.1 -0.1 -0.0
Alcohol intake frequency. 0.1 0.2 1.4 -0.3 -0.5 -0.2 -0.1 -0.2 -0.9 -0.1 -0.1 -0.2 -0.3 0.3 0.6 -0.3 -0.2 -0.3 -0.1 0.1 0.6 -0.4 -0.0 0.3 -0.8 0.3 0.5 -0.1 0.7 -1.2 -1.2 1.1 -0.3 0.0 -0.2 -0.2 -0.2
Comparative height size at age 10 0.4 2.2 5.8 -1.4 -1.6 -1.3 -1.3 -1.5 -0.4 -1.7 -1.8 -1.4 -1.0 -2.4 -1.9 -1.4 -1.4 -1.5 -1.5 -1.2 -0.8 -1.4 -1.5 1.6 -1.8 -1.4 -0.8 -1.6 -1.4 -2.4 -2.3 -0.4 -1.5 -0.2 -1.4 -1.4 -0.9
Number of full sisters 0.6 0.7 2.9 -0.4 -0.9 -1.0 -0.9 -0.6 -0.9 -0.4 -1.0 -0.6 -1.2 -1.2 -1.2 -0.8 -0.8 -0.7 -0.6 -0.6 -1.7 -0.7 -1.0 0.8 -0.1 -1.2 -1.2 -0.4 -0.6 -0.7 0.0 0.3 -0.7 -0.2 -0.8 -0.8 -0.4
Suffer from ‘nerves’ 0.2 0.4 3.0 0.3 1.1 -0.1 0.1 0.3 0.5 0.3 0.3 0.3 0.2 0.9 -0.0 0.3 0.3 0.2 0.2 0.5 0.3 0.4 0.3 -0.4 1.0 -0.0 -0.8 0.3 0.3 1.7 1.6 -0.5 0.5 -0.1 0.3 0.3 0.3
Overall health rating 0.0 0.1 0.9 0.1 0.6 -0.2 0.3 0.4 -0.2 0.2 0.1 0.1 0.2 -0.1 0.4 0.2 0.3 0.2 0.3 0.9 0.1 0.3 0.1 -0.1 0.3 0.2 -0.3 0.2 0.2 0.4 0.4 0.5 0.1 -0.2 0.3 0.3 -0.4
Chest pain or discomfort 0.5 0.7 1.9 -1.4 -0.2 -0.5 -0.8 -0.9 -0.8 -1.2 -1.0 -0.9 -0.5 1.1 0.1 -0.8 -0.8 -0.9 -1.0 -0.9 -0.0 -0.8 -1.2 0.8 -0.5 -0.8 -0.6 -1.2 -0.6 -0.5 -0.7 0.1 -0.8 -0.5 -0.8 -0.7 -1.3
Had major operations 0.4 0.4 1.3 0.5 0.7 1.0 0.5 0.6 -0.1 0.5 0.1 0.6 0.9 0.7 1.0 0.5 0.6 0.5 0.6 0.6 1.1 0.6 0.4 -0.6 0.6 0.3 0.9 0.5 0.2 0.4 1.0 0.6 0.6 0.8 0.6 0.6 0.2
Age at last live birth 0.1 0.2 1.1 -0.0 -0.2 0.2 0.4 0.0 -0.3 -0.0 0.1 0.2 0.9 -0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.4 0.3 0.2 -0.4 0.1 0.5 0.8 -0.0 0.1 -0.1 -0.7 0.9 0.5 1.0 0.2 0.2 0.6
Family relationship satisfaction 0.9 1.1 3.9 -1.1 -0.3 -0.8 -1.2 -1.2 -1.0 -1.0 -1.5 -1.1 -1.2 0.5 -0.4 -1.2 -1.2 -1.2 -1.2 -1.2 -2.0 -1.2 -1.3 1.1 -0.7 -0.7 -0.5 -1.0 -0.1 -1.2 -0.1 1.0 -1.0 -0.2 -1.2 -1.2 -0.7
Leg pain on walking 0.1 0.2 1.3 -0.1 0.9 -0.1 -0.0 0.1 1.1 -0.1 -0.4 0.0 0.5 0.1 0.5 -0.0 0.1 0.1 0.0 0.4 -0.2 -0.1 -0.2 -0.0 0.6 -0.4 -0.0 -0.1 -0.2 -0.1 0.7 1.0 0.0 0.8 0.1 0.1 -0.5
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.0 4.8 -0.9 0.2 -0.9 -0.9 -0.7 0.2 -0.8 -1.1 -0.9 -0.9 -0.5 -0.8 -0.8 -0.7 -0.8 -0.9 0.0 -1.0 -0.7 -1.0 0.9 -0.2 -1.8 -1.9 -0.8 -1.9 0.4 1.0 -2.2 -0.8 -1.5 -0.7 -0.7 -1.0
Commuting to job workplace: Car/motor vehicle 0.2 0.2 1.5 -0.2 0.7 -0.1 -0.3 -0.1 -0.7 -0.3 -0.9 -0.2 -0.1 -0.6 -0.9 -0.1 -0.2 -0.2 -0.2 0.0 0.0 -0.2 -0.8 0.2 0.3 -1.2 -0.4 -0.3 -0.9 -0.2 1.0 0.1 -0.2 -0.1 -0.2 -0.2 -0.5
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 1.7 -0.3 0.8 0.2 0.1 0.1 1.3 -0.1 0.2 0.1 0.2 0.2 0.3 0.1 0.1 0.0 -0.1 0.9 0.8 0.2 0.3 -0.1 0.3 0.5 0.0 -0.2 -0.1 0.9 0.1 -0.7 0.3 0.5 0.1 0.1 0.6
Medication: Aspirin 1.8 2.4 4.8 -1.9 -0.7 -1.4 -1.6 -1.7 -0.8 -1.9 -1.7 -1.7 -1.7 -1.2 -1.3 -1.5 -1.5 -1.7 -1.7 -2.2 -1.6 -1.6 -1.7 1.7 -1.5 -1.0 -1.2 -1.9 -0.7 -1.6 -1.8 -0.8 -1.7 -0.8 -1.5 -1.5 -1.9
Supplements: Vitamin C 5.0 5.9 13.6 -2.7 -3.7 -2.8 -2.3 -2.6 -0.6 -2.7 -2.2 -2.8 -2.3 -1.2 -1.4 -2.6 -2.6 -2.6 -2.7 -1.4 -2.2 -2.6 -2.3 2.9 -3.1 -1.5 -1.5 -2.7 -1.2 -2.4 -3.4 -2.3 -2.7 -2.1 -2.6 -2.6 -1.9
Knee pain experienced in last month 0.2 0.3 2.5 0.1 0.4 -0.2 0.0 0.0 -1.6 0.3 0.3 0.0 0.0 -1.3 1.2 -0.1 -0.1 0.1 0.1 -1.2 -0.2 -0.3 -0.5 -0.1 0.0 0.5 0.6 0.2 0.4 -0.5 -0.5 0.9 -0.2 -0.5 -0.1 -0.1 -0.3
Hypertension (Self-reported) 0.2 0.7 1.6 -1.1 0.1 -0.6 -1.0 -0.9 -0.5 -1.0 -1.2 -0.9 -0.7 -0.1 -1.2 -0.9 -0.8 -0.9 -1.0 -0.8 -1.1 -0.9 -1.1 0.8 -0.1 -0.7 -0.7 -1.0 0.3 -0.6 -0.4 0.1 -0.9 0.1 -0.8 -0.8 -1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.1 0.5 0.8 0.6 0.8 0.8 1.0 0.5 0.2 0.6 0.8 0.4 0.5 0.7 0.8 0.8 0.7 0.7 1.0 0.9 0.9 -0.5 0.8 0.1 -0.3 0.5 0.8 0.2 0.5 0.1 0.6 0.9 0.8 0.8 0.8
Illnesses of father: Heart disease 0.8 1.0 3.9 1.1 0.2 1.0 1.0 1.1 -2.0 1.1 0.8 1.0 0.7 0.7 0.9 1.2 0.9 1.0 1.0 1.2 1.9 1.0 1.0 -0.7 0.8 0.5 0.4 1.0 0.7 0.6 1.5 1.5 0.8 -0.2 0.9 0.9 0.9
Illnesses of siblings: Diabetes 0.6 0.7 4.4 -0.8 -0.3 -0.5 -0.4 -0.5 -0.6 -0.9 -1.2 -0.7 -0.4 -2.1 -1.2 -0.5 -0.4 -0.5 -0.6 -0.9 -0.9 -0.5 -0.9 0.7 -0.4 -0.7 -0.4 -0.9 -0.1 -1.8 -1.2 1.1 -0.6 1.0 -0.4 -0.4 -1.1
Smoking status: Previous 0.2 0.3 2.5 -0.2 0.6 -0.1 -0.3 -0.3 -0.9 -0.2 -0.0 -0.2 0.2 1.6 -1.2 -0.1 -0.2 -0.2 -0.2 -1.1 -0.4 -0.3 -0.2 0.1 -0.0 -0.0 -0.2 -0.2 -0.2 0.3 -0.2 -0.8 -0.1 -0.1 -0.2 -0.2 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 4.6 0.8 -0.6 0.5 0.7 0.5 -0.8 0.5 0.3 0.6 0.5 -1.2 2.2 0.6 0.6 0.5 0.5 -0.7 1.0 0.4 0.8 -0.5 -0.4 1.1 1.5 0.5 1.1 -0.8 -0.1 1.5 0.4 0.2 0.6 0.6 0.6
Whole body fat-free mass 0.1 0.4 3.6 0.0 -0.2 -0.3 -0.3 -0.1 0.2 -0.1 -0.7 -0.1 0.1 -1.8 -0.1 -0.0 -0.2 -0.2 -0.1 0.2 0.6 -0.3 -0.7 0.2 0.1 -0.6 -0.5 -0.1 0.5 -1.0 -0.6 1.6 -0.2 1.9 -0.2 -0.2 -0.6
Leg fat-free mass (right) 0.1 0.4 4.8 0.2 -0.0 0.1 -0.2 -0.0 -0.2 0.2 -0.4 0.1 0.1 -1.2 -0.1 0.1 -0.1 -0.1 0.0 -0.1 0.5 -0.2 -0.5 0.0 0.1 -0.3 -0.2 0.2 0.9 -1.0 -0.5 2.2 -0.0 1.9 -0.1 -0.1 -0.5
Arm fat percentage (left) 0.4 1.7 6.3 1.4 1.6 1.6 1.1 1.3 -0.3 1.5 1.2 1.3 1.0 1.5 1.4 1.4 1.2 1.1 1.3 0.4 0.6 1.0 1.2 -1.2 1.4 1.4 1.1 1.5 2.0 0.8 1.1 2.5 1.2 1.3 1.2 1.2 0.5
Average weekly red wine intake 2.0 2.9 9.5 -1.6 -1.6 -1.9 -1.8 -2.0 -0.7 -1.7 -1.8 -1.7 -1.6 -1.5 -0.8 -1.8 -1.8 -1.8 -1.8 -3.1 -2.2 -1.8 -1.8 1.9 -1.7 -1.6 -1.2 -1.7 -1.8 -1.9 -1.4 -0.9 -1.8 -0.9 -1.8 -1.8 -1.6
Handedness (chirality/laterality): Left-handed 0.3 0.4 6.0 -0.4 0.1 0.2 0.2 0.1 2.4 -0.2 0.0 -0.0 0.6 -0.2 0.9 0.1 0.1 0.1 0.0 1.7 0.5 0.1 0.1 0.1 -0.3 0.3 0.2 -0.2 0.1 0.2 -0.4 0.2 0.3 0.9 0.1 0.1 -0.1
Mood swings 0.1 0.3 1.6 0.8 -0.2 0.4 0.1 0.2 0.0 0.7 0.6 0.4 -0.0 0.7 1.2 0.3 0.2 0.1 0.3 -1.2 -0.0 -0.0 0.5 -0.3 -0.0 0.0 0.6 0.7 -0.0 0.4 1.0 -0.2 0.2 -0.9 0.2 0.2 0.3
Loneliness, isolation 0.6 0.8 2.4 -0.8 -1.3 -0.9 -0.9 -0.8 -1.4 -0.7 -0.7 -0.8 -1.1 -1.5 -0.3 -0.9 -1.0 -0.8 -0.8 -0.9 0.1 -1.0 -0.5 0.7 -1.1 -0.6 -0.5 -0.7 -0.4 -1.3 -1.1 0.3 -1.0 -1.1 -1.0 -1.0 -1.1
Long-standing illness, disability or infirmity 0.4 0.6 2.1 -1.1 -0.1 -0.6 -0.5 -0.6 -1.4 -1.1 -0.9 -0.8 -0.6 -0.9 0.2 -0.8 -0.4 -0.6 -0.8 -0.7 -0.7 -0.6 -0.3 0.7 -0.8 -0.3 -0.3 -1.1 -0.4 -0.6 -0.5 -0.8 -0.8 -1.1 -0.4 -0.4 -1.2
Ever had bowel cancer screening 0.1 0.1 0.7 -0.1 -0.3 -0.1 0.0 0.0 -0.9 0.1 -0.0 -0.0 0.4 0.2 -0.8 -0.0 0.0 0.1 0.1 -0.5 0.5 -0.0 -0.5 -0.1 0.1 -0.5 0.3 0.1 -0.1 -0.5 0.1 0.3 0.0 -0.3 0.0 0.0 0.0
Diabetes diagnosed by doctor 1.4 2.2 3.9 1.5 1.7 1.5 1.5 1.6 0.1 1.6 1.7 1.7 1.6 1.6 1.4 1.6 1.6 1.6 1.6 1.0 2.0 1.5 1.3 -1.6 1.4 1.5 1.8 1.6 1.5 1.1 1.0 1.4 1.5 1.2 1.6 1.6 1.4
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.9 -0.5 -0.5 0.1 -0.2 -0.3 0.9 -0.5 -0.2 -0.4 0.0 -0.9 0.3 -0.2 -0.3 -0.3 -0.3 0.2 -0.4 -0.1 0.1 0.2 -0.1 -0.1 -0.7 -0.5 -0.5 0.1 -0.6 -0.7 -0.1 0.3 -0.2 -0.3 -0.4
Friendships satisfaction 0.1 0.2 0.8 -0.3 0.3 0.1 -0.4 -0.4 -0.4 -0.2 -0.6 -0.3 -0.3 -0.8 0.3 -0.4 -0.3 -0.4 -0.3 -0.9 -0.4 -0.3 -0.5 0.2 -0.3 -0.7 -0.2 -0.2 -0.4 -0.7 0.2 0.5 -0.1 0.4 -0.3 -0.3 -0.0
Qualifications: nursing, teaching 1.5 2.4 5.1 -1.9 -1.3 -1.3 -1.4 -1.6 0.1 -1.9 -1.8 -1.6 -1.1 -1.9 -1.4 -1.5 -1.4 -1.5 -1.7 -2.3 -1.8 -1.4 -1.7 1.8 -1.2 -1.6 -1.2 -1.9 -2.1 -1.6 -1.1 -1.2 -1.4 -1.0 -1.4 -1.4 -1.7
Commuting to job workplace: Walk 0.1 0.1 0.8 -0.2 -0.2 -0.2 -0.3 -0.2 0.6 -0.1 -0.3 -0.2 -0.2 0.8 -0.2 -0.1 -0.3 -0.3 -0.3 0.7 -0.9 -0.2 -0.3 0.3 -0.3 -0.2 -0.4 -0.1 0.3 -0.2 -0.3 0.2 -0.1 0.7 -0.3 -0.2 -0.2
Eye problems/disorders: Cataract 0.7 0.8 4.6 0.5 1.3 0.9 1.1 1.0 0.6 0.5 0.9 0.8 1.1 -1.2 0.7 0.9 1.1 0.9 0.8 2.2 1.2 1.1 0.7 -0.6 0.5 1.1 0.4 0.5 0.0 0.9 0.4 -0.1 0.9 -0.0 1.1 1.1 0.4
Mouth/teeth dental problems: Mouth ulcers 0.2 0.4 2.5 0.6 0.3 0.4 0.9 0.6 0.5 0.4 0.4 0.4 1.0 0.3 0.3 0.5 0.7 0.6 0.7 0.7 1.6 0.7 0.3 -0.5 0.2 0.5 0.3 0.4 0.7 -0.1 -0.4 0.8 0.6 0.7 0.7 0.7 0.2
Medication for cholesterol 1.0 1.5 6.3 1.4 0.5 1.4 1.1 1.3 2.5 1.4 1.2 1.2 1.1 -0.5 0.5 1.2 1.1 1.1 1.4 1.7 0.3 1.4 1.4 -1.2 1.5 0.6 0.1 1.4 0.3 1.3 0.8 0.1 1.4 2.2 1.1 1.1 1.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.2 0.2 1.0 -0.0 0.5 0.5 0.4 0.3 -0.7 0.0 0.1 0.4 0.7 0.3 0.6 0.3 0.4 0.2 0.1 0.5 0.5 0.3 0.4 -0.4 0.2 0.6 0.8 0.0 1.0 0.3 0.5 0.7 0.4 0.2 0.4 0.5 0.5
Back pain experienced in last month 0.5 0.8 2.6 -0.3 -0.6 -0.7 -0.9 -0.8 -1.4 -0.5 -0.2 -0.9 -1.4 -0.4 0.0 -1.0 -1.1 -0.8 -0.7 -0.8 -0.5 -1.1 -0.6 0.8 -1.3 -0.1 -0.4 -0.5 -0.7 -1.0 -1.2 -1.2 -1.1 -1.6 -1.0 -1.1 -0.5
Mineral and other dietary supplements 0.8 1.0 3.7 1.2 0.4 1.4 0.9 1.0 0.5 1.1 1.1 1.2 0.8 1.9 0.6 1.0 1.1 1.1 1.1 0.7 0.4 1.0 0.8 -1.3 1.2 0.7 0.7 1.1 0.3 1.4 1.6 0.6 1.0 -0.1 1.1 1.1 0.6
Breast cancer (self-reported) 0.5 0.6 1.3 0.5 0.8 0.8 0.9 0.8 -0.8 0.7 1.1 0.7 0.8 1.0 0.5 0.7 0.8 0.8 0.7 0.4 0.9 0.9 0.9 -0.8 0.7 1.0 0.7 0.7 0.8 1.0 0.4 -0.5 0.8 -0.4 0.8 0.8 1.1
Asthma (self-reported) 0.5 1.1 5.2 -0.9 -0.2 -0.8 -0.7 -0.9 -1.6 -1.0 -1.1 -1.0 -1.2 -1.7 1.0 -0.8 -0.7 -0.8 -0.9 -1.9 -0.3 -1.0 -0.7 0.7 -1.5 -0.8 0.0 -1.0 -0.4 -1.3 -0.4 -0.9 -1.0 -2.3 -0.7 -0.7 -1.0
Osteoporosis (self-reported) 0.2 0.2 2.0 -0.1 -0.6 -0.0 0.0 -0.2 -0.6 -0.3 -0.1 -0.2 0.0 0.0 0.1 -0.2 -0.2 -0.2 -0.2 0.1 0.2 -0.4 0.2 0.3 -1.4 0.1 0.8 -0.2 0.2 -1.2 -1.0 -0.1 -0.4 -1.0 -0.2 -0.2 0.0
Osteoarthritis (self-reported) 0.5 0.6 1.7 0.8 1.3 0.8 0.9 0.8 1.2 0.6 0.6 0.7 0.8 -1.0 -0.4 0.8 0.9 0.7 0.7 0.7 1.1 0.8 0.9 -0.6 0.4 0.5 0.6 0.6 0.7 -0.2 -0.1 1.1 0.8 1.0 0.9 0.9 0.7
Medication: Aspirin 2.0 2.6 5.6 -2.1 -0.6 -1.5 -1.7 -1.8 -0.7 -2.0 -2.0 -1.8 -1.8 -1.3 -1.2 -1.6 -1.5 -1.7 -1.8 -2.4 -1.8 -1.6 -1.6 1.8 -1.4 -1.3 -1.6 -2.0 -0.8 -1.6 -1.7 -0.9 -1.7 -0.6 -1.5 -1.5 -1.9
Medication: Gliclazide 0.7 0.8 2.0 0.9 1.2 1.1 0.9 1.0 -0.0 1.1 1.4 1.0 0.8 0.7 -0.0 1.0 0.9 0.9 1.0 -0.4 1.1 1.0 1.0 -0.9 0.9 0.7 0.4 1.1 0.6 1.2 0.5 -0.7 0.8 -0.3 0.9 0.9 1.1
Illnesses of father: None of the above (group 1) 3.3 4.1 6.2 -2.2 -1.8 -2.1 -2.2 -2.2 -1.5 -2.2 -2.1 -2.2 -2.1 -0.9 -2.4 -2.3 -2.2 -2.2 -2.2 -1.8 -2.5 -2.2 -2.3 2.2 -2.0 -2.1 -1.6 -2.2 -1.3 -1.8 -1.7 -1.6 -2.1 -1.4 -2.2 -2.2 -1.7
Smoking status: Current 2.5 3.9 9.4 1.8 1.6 1.8 2.0 2.0 2.1 1.9 2.1 2.0 1.7 0.4 2.4 2.0 2.0 2.0 2.0 3.1 1.6 2.0 2.2 -1.8 2.1 2.2 1.9 1.8 1.9 2.2 1.7 1.7 2.1 2.1 2.0 2.0 1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.5 3.4 1.8 -0.1 1.3 1.3 1.4 0.8 1.6 1.8 1.4 1.0 0.1 1.3 1.5 1.2 1.3 1.5 1.4 1.5 1.3 1.0 -1.4 0.5 1.3 1.4 1.6 0.7 0.9 0.4 0.0 1.2 -0.0 1.2 1.2 1.7
Whole body water mass 0.1 0.4 3.5 -0.0 -0.2 -0.4 -0.3 -0.2 0.3 -0.1 -0.7 -0.1 0.0 -1.8 -0.2 -0.0 -0.2 -0.2 -0.2 0.2 0.6 -0.3 -0.8 0.2 0.1 -0.6 -0.6 -0.1 0.5 -0.9 -0.6 1.5 -0.2 1.9 -0.2 -0.2 -0.6
Leg predicted mass (right) 0.1 0.4 4.7 0.2 0.0 0.1 -0.2 -0.0 -0.2 0.2 -0.5 0.1 0.1 -1.2 -0.1 0.1 -0.1 -0.1 0.0 -0.2 0.5 -0.2 -0.5 0.0 0.2 -0.3 -0.2 0.2 0.8 -1.0 -0.4 2.2 -0.0 1.9 -0.1 -0.1 -0.5
Arm fat mass (left) 0.2 1.0 5.6 1.1 1.4 1.2 0.8 1.0 -0.4 1.1 0.7 1.0 0.7 0.5 0.9 1.1 0.9 0.8 1.0 0.3 0.6 0.7 0.7 -0.9 1.1 1.0 0.8 1.1 1.8 0.3 0.7 2.4 0.8 1.5 0.9 0.9 0.2
Number of self-reported non-cancer illnesses 0.1 0.2 1.9 -0.0 1.3 0.0 0.3 0.2 -1.0 0.0 -0.1 0.1 -0.1 0.1 -0.0 0.2 0.4 0.2 0.1 -0.4 0.4 0.2 0.2 -0.3 0.1 0.4 0.4 -0.0 1.4 -0.2 0.1 0.5 -0.0 -0.3 0.4 0.4 -0.1
Average weekly champagne plus white wine intake 3.6 5.0 10.7 -2.3 -2.5 -2.4 -2.0 -2.5 -1.2 -2.4 -1.7 -2.5 -1.8 -1.9 0.2 -2.4 -2.4 -2.5 -2.4 -2.4 -2.2 -2.5 -1.9 2.5 -3.2 -1.3 -1.4 -2.4 -2.0 -2.3 -3.3 -1.5 -2.3 -2.1 -2.4 -2.4 -2.2
Miserableness 0.8 1.5 4.2 -0.9 -0.7 -1.2 -1.4 -1.2 -0.5 -1.0 -1.3 -1.2 -1.4 0.1 0.2 -1.2 -1.3 -1.3 -1.3 -2.0 -1.2 -1.6 -0.8 1.3 -1.5 -1.3 -0.4 -1.0 -1.1 -1.1 -0.2 -1.1 -1.4 -2.0 -1.3 -1.3 -1.2
Guilty feelings 0.4 0.6 1.5 1.1 0.6 0.8 0.7 0.7 1.2 1.0 1.2 0.9 1.2 -0.1 0.8 0.8 0.6 0.7 0.8 0.1 0.5 0.6 0.9 -0.9 0.5 0.8 0.6 1.0 -0.0 0.9 0.6 0.2 0.9 0.5 0.6 0.7 0.9
Wears glasses or contact lenses 0.2 0.3 1.8 -0.3 -0.2 -0.3 -0.2 -0.4 0.1 -0.3 -0.6 -0.4 -0.1 -1.3 -0.2 -0.2 -0.3 -0.3 -0.2 -0.5 0.5 -0.2 -0.4 0.3 -0.4 -0.6 -0.3 -0.3 -0.5 -1.2 -0.8 0.8 -0.3 1.0 -0.3 -0.3 -0.3
Ever taken oral contraceptive pill 0.2 0.2 2.0 0.5 0.4 -0.1 -0.1 -0.1 0.4 0.3 0.7 0.1 -0.0 -0.2 1.0 -0.1 -0.2 -0.1 0.1 -0.4 -1.4 -0.2 0.4 -0.2 -0.2 0.8 0.5 0.3 0.3 0.3 -0.6 0.6 0.1 0.9 -0.2 -0.2 0.3
Hearing aid user 3.4 3.8 5.6 -1.9 -1.9 -2.1 -2.1 -2.2 -1.8 -1.9 -1.8 -2.2 -2.0 -1.1 -1.3 -2.2 -2.2 -2.1 -2.1 -1.8 -2.0 -2.2 -2.1 2.1 -2.4 -1.7 -1.5 -2.0 -1.6 -2.1 -1.9 -1.2 -2.2 -1.8 -2.2 -2.2 -2.1
Mother’s age at death 0.5 0.6 4.0 -0.9 -1.1 -0.8 -0.2 -0.6 0.1 -0.9 -0.1 -0.7 -0.3 -1.3 -0.6 -0.5 -0.4 -0.6 -0.7 -0.8 -0.8 -0.4 -0.2 0.5 -1.2 0.2 -0.2 -0.9 -0.4 -0.4 -2.0 -1.7 -0.5 -0.6 -0.4 -0.4 -0.4
Financial situation satisfaction 0.2 0.3 2.8 -0.4 -0.1 -0.2 -0.2 -0.3 -0.7 -0.5 -0.8 -0.4 -0.0 0.1 -1.1 -0.3 -0.2 -0.3 -0.3 0.2 -0.5 -0.2 -0.2 0.3 0.1 -0.1 0.0 -0.5 0.7 -0.5 -0.1 1.7 -0.0 1.4 -0.2 -0.2 -0.1
Tinnitus: Yes, now most or all of the time 1.3 1.5 2.8 -1.3 -1.0 -1.1 -1.3 -1.5 -0.6 -1.2 -1.1 -1.4 -1.1 -1.4 0.2 -1.5 -1.5 -1.4 -1.3 -1.7 -0.8 -1.6 -1.0 1.2 -1.5 -0.7 -0.5 -1.1 -1.3 -1.4 -1.2 -0.4 -1.3 -0.9 -1.5 -1.5 -1.1
Commuting to job workplace: Public transport 0.5 0.6 1.9 0.5 -0.2 0.9 0.8 0.7 0.2 0.8 1.3 0.6 0.5 -0.5 1.4 0.6 0.6 0.7 0.7 0.0 0.3 0.7 1.1 -0.8 0.2 1.3 0.9 0.8 0.9 0.8 -0.0 -0.5 0.8 -0.4 0.6 0.6 1.2
Eye problems/disorders: Glaucoma 1.7 2.0 3.4 1.3 1.6 1.8 1.4 1.3 0.3 1.3 1.4 1.4 1.6 1.2 1.4 1.5 1.4 1.2 1.3 1.4 1.0 1.2 1.1 -1.4 1.3 1.7 1.8 1.3 1.8 1.1 1.0 1.7 1.5 1.5 1.4 1.4 1.7
Medication: Blood pressure 0.1 0.3 1.8 -0.3 0.9 -0.2 0.3 0.3 -1.2 -0.2 -0.4 0.2 0.3 1.4 0.1 0.2 0.4 0.3 0.0 0.2 0.8 0.2 0.0 -0.3 0.1 -0.0 0.6 -0.2 0.6 -0.3 0.7 0.8 0.0 -0.8 0.4 0.4 -0.4
Pain type(s) experienced in last month: Hip pain 0.5 0.7 3.1 -0.8 -0.7 -0.7 -0.3 -0.6 -0.7 -0.9 -1.1 -0.8 -0.6 -0.4 0.9 -0.5 -0.5 -0.6 -0.6 -0.8 -1.3 -0.9 -0.5 0.9 -1.4 -0.2 1.0 -0.9 0.1 -1.8 -0.7 0.1 -0.9 -1.2 -0.5 -0.5 -0.3
Supplements: Fish oil (including cod liver oil) 0.3 0.4 2.3 -0.9 0.3 -1.1 -0.6 -0.5 0.3 -0.8 -0.9 -0.8 -0.6 -1.5 0.2 -0.4 -0.6 -0.7 -0.7 0.1 -0.3 -0.5 -0.5 0.9 -0.5 -0.5 -0.6 -0.8 0.1 -0.6 -0.5 -0.5 -0.7 0.0 -0.6 -0.6 -0.4
High cholesterol (Self-reported) 0.4 0.7 4.0 -1.2 -0.5 -1.1 -0.6 -0.7 -2.0 -1.1 -1.1 -0.8 -0.4 0.2 -1.8 -0.7 -0.5 -0.7 -0.9 -0.5 -0.6 -0.7 -0.6 0.8 -0.3 -0.8 -0.4 -1.1 -0.1 -0.5 -0.1 -0.5 -0.7 -0.8 -0.5 -0.5 -1.0
Medication: Bendroflumethiazide 0.1 0.2 1.5 -0.0 1.2 0.2 0.1 0.2 0.1 0.0 -0.3 0.3 0.3 1.0 -0.9 0.1 0.3 0.1 0.1 -0.5 0.4 0.3 -0.2 -0.3 0.9 -0.6 -0.2 0.1 0.1 0.5 1.0 -0.1 0.2 0.2 0.3 0.3 0.0
Medication: Paracetamol 0.7 1.0 2.2 1.5 0.8 1.3 1.1 1.2 -0.7 1.3 1.4 1.1 1.1 0.4 0.8 1.1 1.1 1.2 1.3 0.3 0.7 1.1 1.0 -1.3 1.0 0.8 0.9 1.3 0.6 0.6 0.6 0.7 1.1 0.3 1.1 1.1 0.7
Medication: Lisinopril 0.4 0.6 2.0 -0.6 -0.1 -0.9 -0.9 -0.5 -0.6 -0.5 -0.8 -0.6 -1.0 -0.1 -1.1 -0.6 -0.6 -0.6 -0.7 -1.0 -0.5 -0.6 -1.1 0.5 -0.2 -1.4 -1.1 -0.5 -0.6 -0.0 0.6 -1.2 -0.7 -1.1 -0.6 -0.6 -0.8
Medication: Atorvastatin 0.6 0.7 3.1 -1.0 0.6 -0.6 -0.9 -0.8 -0.9 -0.9 -0.4 -0.8 -0.7 -0.2 -0.5 -0.7 -0.7 -0.9 -0.9 -0.7 -0.5 -0.7 -1.1 0.6 -0.6 -0.8 -1.2 -0.9 -1.6 0.0 -0.5 -1.8 -0.7 -1.1 -0.7 -0.7 -1.3
Illnesses of father: High blood pressure 0.6 0.7 1.6 1.3 1.0 1.2 0.7 0.9 0.8 1.2 1.1 0.9 0.7 0.7 1.0 0.9 0.7 0.8 1.0 0.8 0.9 0.7 0.5 -1.0 0.8 0.4 0.2 1.2 0.1 1.0 0.8 0.5 0.8 0.5 0.7 0.7 0.3
Alcohol drinker status: Never 0.2 0.2 1.9 -0.3 -0.8 -0.1 -0.2 -0.4 -0.1 -0.3 0.2 -0.3 -0.2 -0.5 -0.3 -0.4 -0.4 -0.3 -0.3 0.5 0.6 -0.4 -0.2 0.4 -0.8 0.5 0.1 -0.3 -0.3 -0.5 -1.4 -0.2 -0.3 0.2 -0.4 -0.4 0.0
Ever smoked 0.2 0.3 2.1 0.2 1.5 0.6 0.1 0.3 0.9 0.3 0.2 0.2 0.6 0.9 0.1 0.3 0.3 0.3 0.3 0.6 -0.3 0.3 0.2 -0.4 0.8 -0.1 -0.5 0.3 -0.1 1.0 0.8 -0.0 0.5 0.8 0.3 0.3 -0.6
Basal metabolic rate 0.1 0.4 3.5 0.1 0.1 -0.2 -0.2 -0.0 0.1 0.0 -0.5 0.1 0.1 -1.6 0.0 0.1 -0.0 -0.1 -0.0 0.1 0.6 -0.2 -0.6 0.1 0.2 -0.4 -0.4 0.0 0.7 -0.8 -0.4 1.8 -0.0 1.9 -0.0 -0.0 -0.5
Leg fat percentage (left) 0.1 0.4 2.1 0.5 1.4 0.7 0.5 0.6 -0.0 0.6 0.5 0.5 0.4 0.5 0.6 0.6 0.6 0.4 0.5 0.3 0.3 0.4 0.5 -0.5 0.8 0.8 0.3 0.6 1.5 0.6 0.6 1.3 0.6 0.8 0.6 0.6 0.1
Arm fat-free mass (left) 0.1 0.5 3.8 -0.6 -0.1 -0.9 -0.6 -0.5 0.2 -0.7 -1.0 -0.5 -0.3 -1.9 -0.7 -0.4 -0.4 -0.6 -0.6 0.0 0.2 -0.5 -1.2 0.6 -0.1 -0.8 -0.9 -0.7 0.2 -0.9 -0.8 0.7 -0.5 1.2 -0.4 -0.4 -1.0
Number of operations (self-reported) 0.1 0.2 2.5 -0.0 -0.7 0.3 -0.1 0.0 -1.6 -0.1 -0.5 -0.1 0.2 0.7 0.4 -0.1 -0.0 -0.1 -0.0 0.9 0.2 -0.2 -0.3 -0.1 -0.2 -0.2 0.4 -0.1 0.1 -0.5 0.5 1.0 -0.1 0.0 -0.0 -0.0 -0.7
Average weekly beer plus cider intake 0.3 0.5 3.4 0.8 0.8 0.5 0.3 0.6 -1.3 0.7 0.2 0.6 0.2 0.4 0.9 0.4 0.5 0.6 0.6 0.6 1.1 0.5 -0.4 -0.7 1.0 -0.2 0.1 0.7 0.6 0.6 1.9 1.0 0.4 -0.1 0.5 0.5 -0.0
Irritability 0.2 0.4 2.5 0.7 0.4 0.4 0.1 0.4 1.1 0.6 0.4 0.4 0.1 1.6 0.7 0.6 0.2 0.2 0.4 1.1 0.4 0.2 0.4 -0.1 0.5 -0.4 -0.4 0.6 0.0 1.0 1.3 -0.2 0.3 -0.0 0.2 0.2 0.2
Risk taking 3.1 4.5 8.7 -1.9 -1.6 -2.3 -2.4 -2.2 -0.1 -2.1 -2.6 -2.1 -2.2 -0.3 -3.0 -2.2 -2.2 -2.1 -2.1 -2.1 -2.1 -2.1 -2.6 2.1 -1.5 -2.9 -2.6 -2.1 -2.7 -1.7 -0.8 -1.6 -2.2 -1.0 -2.2 -2.2 -2.5
Ever had prostate specific antigen (PSA) test 1.5 1.7 3.5 -1.4 -0.9 -1.2 -1.6 -1.5 0.8 -1.4 -1.4 -1.4 -1.2 -1.3 -1.0 -1.3 -1.4 -1.4 -1.4 -1.1 -1.0 -1.4 -1.6 1.3 -0.9 -1.5 -1.4 -1.4 -1.9 -1.1 -1.2 -1.4 -1.2 0.2 -1.4 -1.4 -1.3
Fractured/broken bones in last 5 years 1.5 2.0 3.8 1.7 1.6 1.4 1.5 1.6 1.2 1.5 1.1 1.6 1.5 0.8 0.5 1.5 1.7 1.7 1.7 0.8 1.6 1.6 1.4 -1.6 1.9 0.5 1.0 1.5 0.8 1.2 1.9 1.1 1.4 1.2 1.7 1.7 0.6
Age started oral contraceptive pill 0.4 0.5 3.1 -0.6 -0.7 -0.2 -0.7 -0.7 0.3 -0.5 -0.0 -0.8 -0.9 -1.1 -1.4 -0.7 -0.8 -0.7 -0.7 -0.1 -0.3 -0.8 -0.6 0.6 -1.0 -0.1 -0.3 -0.5 -0.1 -0.9 -1.8 -0.8 -0.7 -0.5 -0.8 -0.8 -0.1
Diastolic blood pressure, automated reading 0.1 0.3 3.4 0.2 0.2 0.3 0.3 0.4 -0.3 0.1 -0.3 0.3 0.0 -0.1 -0.1 0.2 0.3 0.3 0.3 1.9 0.6 0.3 0.0 -0.2 0.6 0.0 0.2 0.2 0.7 -0.1 0.5 1.5 0.3 0.9 0.3 0.3 0.0
Ever depressed for a whole week 3.4 4.2 7.6 -2.0 -1.6 -2.4 -2.3 -2.3 -0.8 -2.1 -1.9 -2.3 -1.8 -1.2 -1.4 -2.3 -2.3 -2.3 -2.2 -2.3 -2.2 -2.5 -1.8 2.1 -2.5 -0.9 -1.5 -2.1 -1.5 -1.9 -2.8 -1.6 -2.2 -1.3 -2.3 -2.3 -2.4
Unable to work because of sickness or disability 0.2 0.2 1.8 -0.2 -0.4 -0.5 -0.1 -0.2 -1.3 -0.3 -0.2 -0.2 -0.0 0.5 1.3 -0.4 -0.2 -0.2 -0.2 -0.8 -0.8 -0.2 -0.2 0.2 -0.2 -0.1 -0.0 -0.3 -0.2 -0.3 -0.3 0.4 -0.2 -0.5 -0.2 -0.2 -0.6
Commuting to job workplace: Cycle 1.7 2.1 5.2 -1.6 -1.4 -1.1 -1.5 -1.6 -0.0 -1.6 -1.3 -1.6 -1.3 -2.2 -0.9 -1.7 -1.6 -1.6 -1.5 -0.8 -0.8 -1.7 -1.4 1.5 -1.7 -1.1 -0.8 -1.5 -1.2 -2.0 -2.3 -0.4 -1.4 -0.6 -1.6 -1.6 -1.5
Myopia 0.1 0.1 0.6 -0.0 -0.2 0.1 -0.2 -0.2 0.8 -0.1 -0.5 -0.2 0.3 0.6 0.7 -0.2 -0.2 -0.1 -0.1 -0.4 -0.1 -0.1 -0.5 0.1 0.0 -0.5 -0.6 -0.1 -0.2 -0.3 -0.2 0.3 -0.2 0.4 -0.2 -0.2 -0.3
Vascular/heart problems diagnosed by doctor 0.4 1.1 2.8 1.5 0.2 0.9 1.2 1.0 1.1 1.3 1.7 1.1 1.1 0.2 1.1 1.1 0.9 1.1 1.2 0.4 1.2 1.0 1.5 -1.1 0.3 1.3 1.0 1.3 0.0 0.9 0.2 -0.3 1.1 0.4 0.9 0.9 1.6
Cholesterol lowering medication 2.6 3.8 12.0 -2.3 -1.1 -2.3 -1.9 -1.9 -3.5 -2.2 -2.3 -1.9 -2.3 0.1 -2.2 -1.8 -1.8 -1.9 -2.1 -2.2 -1.0 -2.0 -2.4 1.9 -1.8 -2.0 -1.2 -2.2 -0.9 -2.0 -0.9 -0.9 -2.2 -2.5 -1.8 -1.8 -2.1
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 1.3 -0.8 0.1 -0.5 -0.6 -0.4 0.6 -0.7 -0.9 -0.7 -0.1 -0.1 -1.1 -0.6 -0.4 -0.5 -0.6 0.8 0.5 -0.4 -0.8 0.7 0.2 -0.8 -1.0 -0.7 -0.0 -0.5 -0.4 0.3 -0.4 0.7 -0.4 -0.4 -1.2
Pain experienced in last month 1.4 2.3 6.0 1.2 0.1 1.5 1.5 1.6 1.6 1.3 1.5 1.4 1.8 2.1 0.2 1.6 1.5 1.5 1.4 2.5 2.4 1.6 1.5 -1.6 1.7 0.3 0.3 1.4 0.5 2.2 2.1 -0.0 1.7 0.8 1.5 1.5 1.1
Supplements: Calcium 0.6 0.7 3.1 0.6 -0.6 0.3 0.9 0.6 -0.7 0.7 0.8 0.7 0.8 0.1 1.0 0.7 0.7 0.7 0.7 0.1 1.3 0.5 0.6 -0.6 -0.3 1.3 1.7 0.6 1.8 -0.6 -0.9 0.6 0.5 0.5 0.7 0.7 1.0
Basal cell carcinoma (self-reported) 0.2 0.2 1.5 0.1 1.2 0.3 0.4 0.3 -0.4 0.0 0.2 0.3 0.6 -0.3 0.1 0.4 0.5 0.3 0.2 0.8 0.5 0.5 0.4 -0.4 0.5 1.0 0.1 0.0 0.5 0.7 0.1 0.5 0.5 0.9 0.5 0.5 0.2
Heart attack/myocardial infarction (self-reported) 0.1 0.1 0.5 -0.3 -0.5 -0.5 -0.1 -0.1 0.1 -0.5 -0.7 -0.2 -0.3 0.2 0.2 -0.1 -0.1 -0.3 -0.3 -0.3 -0.5 -0.1 -0.3 0.4 -0.4 -0.4 -0.2 -0.5 -0.2 -0.5 -0.2 0.5 -0.3 -0.2 -0.1 -0.1 -0.6
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 1.4 -0.9 0.3 -0.8 -0.8 -0.8 -1.2 -0.8 -0.8 -0.8 -0.3 0.6 -0.4 -0.6 -0.7 -0.7 -0.8 -0.9 -0.8 -0.7 -1.0 0.4 -0.5 -0.6 -1.0 -0.8 -0.7 -0.2 -0.3 -1.0 -0.6 -0.3 -0.7 -0.7 -1.2
Heart disease (siblings) 1.0 1.2 2.3 -0.9 -0.9 -0.8 -1.2 -1.1 -1.1 -1.0 -0.9 -1.1 -1.5 -0.3 -1.3 -1.2 -1.3 -1.4 -1.2 -1.1 -1.3 -1.4 -0.7 1.1 -1.3 -0.5 -0.1 -1.0 -0.7 -1.2 -1.2 -0.6 -1.2 -1.4 -1.3 -1.3 -0.6
Alcohol drinker status: Previous 0.5 0.6 1.5 -0.9 -0.2 -0.7 -0.6 -0.7 -1.0 -0.9 -0.8 -0.8 -0.4 1.1 -0.1 -0.9 -0.8 -0.9 -0.8 0.1 -0.2 -1.0 -0.6 0.7 -1.2 -0.3 0.2 -0.9 -0.4 -1.1 -1.1 0.3 -0.6 -0.6 -0.8 -0.8 -0.7
Pack years of smoking 0.3 0.5 2.1 0.4 0.9 0.6 0.6 0.7 -0.6 0.4 0.2 0.6 0.3 1.0 0.4 0.7 0.8 0.7 0.5 0.9 0.7 0.7 0.5 -0.7 0.8 0.3 0.6 0.4 1.3 0.8 1.5 0.5 0.6 0.1 0.8 0.8 0.6
Impedance of whole body 0.1 0.4 4.7 -0.1 -0.5 0.2 0.2 -0.1 -1.3 -0.1 0.3 -0.1 -0.6 0.4 0.8 -0.3 -0.2 -0.1 -0.1 -0.5 -0.5 -0.1 0.5 0.3 -1.0 0.7 1.1 -0.2 -0.1 -0.3 -0.3 -0.6 -0.3 -2.2 -0.2 -0.2 0.7
Leg fat mass (left) 0.1 0.3 2.2 0.4 1.0 0.6 0.4 0.5 -0.3 0.5 0.2 0.4 0.3 0.0 0.5 0.6 0.5 0.3 0.4 0.2 0.4 0.3 0.2 -0.4 0.6 0.4 0.1 0.5 1.2 0.2 0.3 1.5 0.4 1.0 0.5 0.5 -0.1
Arm predicted mass (left) 0.1 0.5 3.8 -0.5 -0.3 -0.9 -0.5 -0.4 0.1 -0.5 -1.0 -0.4 -0.3 -1.9 -0.6 -0.3 -0.4 -0.5 -0.5 0.2 0.2 -0.5 -1.1 0.6 -0.1 -0.8 -0.8 -0.6 0.3 -1.0 -0.7 1.0 -0.5 1.3 -0.4 -0.4 -0.9