Hub : Genes

TYMS

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Hippocampus	0.3752	0.1338	3.8e-03	0.004	NA	0.025	NA	0.019	2.5e-01	NA	8.6e-02	NA	1.1e-01
2	GTEx	Colon Transverse	0.2480	0.0810	2.0e-03	-0.004	NA	-0.004	NA	-0.001	6.1e-01	NA	6.1e-01	NA	3.7e-01
3	GTEx	Esophagus Gastroesophageal Junction	0.2030	0.0780	5.1e-03	0.138	NA	0.032	NA	0.110	1.1e-05	NA	2.6e-02	NA	8.7e-05
4	GTEx	Esophagus Muscularis	0.2240	0.0500	2.8e-07	0.165	NA	0.165	NA	0.142	2.9e-10	NA	2.9e-10	NA	6.3e-09
5	GTEx	Muscle Skeletal	0.0868	0.0270	7.7e-05	0.044	NA	0.034	NA	0.046	3.9e-05	NA	2.8e-04	NA	2.2e-05
6	GTEx	Testis	0.4190	0.0710	1.1e-11	0.197	NA	0.302	NA	0.317	3.9e-09	NA	6.9e-14	NA	1.3e-14
7	ROSMAP	Brain Pre-frontal Cortex	0.1384	0.0311	3.0e-09	0.039	0.075	0.074	0.079	0.075	8.0e-06	6.5e-10	9.6e-10	2.3e-10	7.4e-10
8	TCGA	Pheochromocytoma and Paraganglioma	0.1240	0.0650	4.9e-03	0.078	0.062	0.074	NA	0.071	5.1e-04	1.9e-03	7.3e-04	NA	8.8e-04
9	TCGA	Thyroid Carcinoma	0.0600	0.0290	1.2e-03	0.055	0.024	0.005	NA	0.044	4.7e-06	1.9e-03	9.6e-02	NA	3.5e-05

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.1	1.7	3.9	-0.7	0.7	2.0	1.7	-1.8	-1.5	0.2	-0.2	1.3
Bipolar Disorder or Schizophrenia	0.8	2.1	6.1	-0.1	1.4	2.1	2.5	-1.4	-1.5	0.3	-0.5	1.1
Depressed Affect (Nagel 2018)	0.5	1.0	3.8	-0.3	-1.1	-0.1	-1.0	0.4	0.9	-2.0	1.1	0.9
Depression (Nagel 2018)	0.3	0.4	0.9	-0.9	-0.9	0.0	-0.8	-0.1	-0.2	0.2	-0.8	1.0
Intelligence (Savage-Jansen 2018)	0.6	2.0	5.8	-1.3	-0.8	-1.5	-1.1	1.7	1.5	-0.8	0.8	-2.4
Neuroticism (Nagel 2018)	0.3	0.7	2.5	0.4	-1.3	-0.8	-1.6	0.8	0.8	-0.6	0.1	0.2
Schizophrenia (2018)	0.5	1.0	3.0	0.7	1.4	1.1	1.7	-0.4	-0.7	0.3	-1.1	0.3
Schizophrenia vs Biploar Disorder	1.4	1.8	4.1	-0.7	-1.1	-1.9	-1.1	2.0	1.6	-0.9	0.1	-1.6
Worry (Nagel 2018)	0.8	1.6	3.3	0.1	-1.3	-1.6	-1.5	1.8	1.5	-0.7	0.5	-1.3
Alzheimer’s Disease (in mother)	1.1	1.3	3.9	0.3	0.2	2.0	1.8	-1.5	-0.6	-0.4	0.1	1.3
Alzheimer’s Disease (in father)	2.6	2.9	4.4	2.1	1.7	1.4	1.7	-1.7	-1.8	1.9	-1.8	0.6
Alzheimer’s Disease (including proxy)	2.6	3.8	7.9	1.8	1.7	2.7	2.8	-2.7	-1.8	0.9	-0.8	1.1
Crohns Disease (2017)	0.1	0.3	1.9	-1.4	-0.5	-0.0	-0.6	0.1	0.1	0.2	0.4	0.3
Irritable Bowel Disease (IBD)	0.3	0.7	2.6	-1.6	-0.4	0.9	0.4	-0.9	-0.5	-0.1	0.6	1.1
Ulcerative Colitis (UC)	0.6	1.1	2.2	-1.2	-0.1	1.3	1.0	-1.4	-0.8	-0.7	0.6	1.5
Major Depression (MDD)	0.4	0.5	1.1	0.5	-1.0	-0.1	-0.8	0.1	-0.1	1.0	-1.0	0.7
Reaction Time	0.8	1.5	6.2	0.7	2.0	0.5	0.6	-0.8	-0.8	1.2	-2.5	0.0
Verbal and Numeric Reasoning (VNR)	1.0	2.4	4.5	-1.5	-1.5	-2.1	-1.6	2.1	1.4	0.6	0.2	-1.7
Breast Cancer	0.2	0.4	1.3	-1.2	-0.5	0.5	1.0	0.0	-0.1	0.2	-0.4	0.6
Ovarian Cancer	0.7	0.9	3.1	0.6	1.2	1.1	1.7	-1.1	-0.9	-0.1	-0.6	0.2
Prostate Cancer	0.6	0.9	2.5	-0.3	0.1	1.1	0.9	-0.7	1.0	-1.6	1.4	0.7
Age at First Birth	1.4	2.1	3.7	-0.9	1.7	1.8	1.9	-1.6	-1.7	-0.2	-0.6	1.4
Bipolar Disorder (2011)	1.2	1.2	4.4	2.1	0.7	0.9	1.5	-0.9	-0.9	0.4	0.2	0.8
Body Mass Index (BMI) (2010)	0.1	0.2	0.6	0.8	-0.2	-0.1	-0.3	0.2	0.3	-0.8	-0.1	0.5
Coronary Artery Disease (CAD)	1.0	1.1	2.1	-1.1	-0.2	-1.4	-1.4	1.3	0.2	0.9	-0.9	-1.3
Crohns Disease (2012)	0.3	0.5	1.1	-1.0	0.1	0.5	0.2	-0.5	-0.5	0.6	-1.0	1.0
Mean Putamen Volume	1.1	1.2	3.0	0.4	0.8	1.7	0.8	-1.4	-0.9	-0.4	-0.8	1.7
Fasting Glucose	0.2	0.2	1.2	1.1	-0.4	-0.3	0.3	0.3	-0.1	0.1	0.6	-0.5
HbA1C	0.2	0.2	0.9	-0.4	-0.3	0.1	0.2	-0.5	-0.5	0.5	-0.3	0.9
HDL Cholesterol	0.3	0.5	2.5	0.6	-0.4	-0.5	-0.9	0.2	-0.1	1.6	-0.7	-0.3
LDL Cholesterol	1.0	1.6	4.0	-0.4	0.7	2.0	1.4	-1.7	-1.1	0.3	0.0	1.9
Lupus	1.4	2.1	4.4	-1.2	-1.6	-1.6	-2.1	1.4	1.8	-1.5	-0.0	0.6
Neuroticism (2016)	2.1	3.0	5.6	-0.4	-1.2	-1.7	-2.4	1.9	2.1	-2.2	1.6	-1.2
Primary Biliary Cirrhosis	0.2	0.3	1.2	-0.1	0.4	0.4	0.3	-0.5	-0.4	0.3	-0.7	1.1
Rheumatoid Arthritis	0.7	1.0	2.5	-1.1	0.9	0.6	1.6	-0.9	-1.1	1.3	-0.8	-0.2
Schizophrenia (2014)	0.3	0.7	2.4	0.4	0.4	0.8	1.4	-0.2	-0.7	0.8	-1.6	0.1
Triglycerides	0.4	0.6	1.1	0.9	0.7	0.6	1.0	-0.8	-0.3	-1.0	0.9	0.1
Type 2 Diabetes (T2D) (2012)	0.3	0.4	2.0	0.1	0.8	0.2	0.2	-0.1	0.5	-1.4	0.1	0.7
Ulcerative Colitis	0.6	0.8	2.0	-0.7	-0.0	1.4	1.0	-1.3	-0.6	-0.6	0.8	0.9
Blood Eosinophil Count	0.1	0.5	2.3	1.5	1.0	0.4	-0.1	-0.4	-0.1	-0.7	-0.4	-0.6
Blood Platelet Count	0.2	1.7	4.6	-2.1	-0.9	-0.3	-1.2	-1.1	1.5	-0.9	-0.6	2.1
Blood Red Count	0.3	2.6	9.4	-0.0	0.1	1.7	1.1	-1.0	0.6	-3.1	2.0	2.1
Blood White Count	0.1	0.8	4.0	-1.0	0.0	0.7	0.5	-1.0	-0.2	0.6	-0.7	2.0
Heel T-Score	0.2	1.3	2.2	1.5	-0.2	-1.0	-1.2	1.4	0.6	-1.5	1.0	-1.1
BMI	0.2	1.2	6.8	0.4	0.5	0.5	-0.2	-0.6	-0.6	0.6	-1.4	2.6
Height	0.1	1.5	5.5	0.1	2.2	-0.2	-0.2	0.2	1.3	-2.4	0.1	-1.1
Waist Hip Ratio (WHR)	0.5	2.1	4.5	0.1	-1.0	-1.7	-2.1	1.7	1.9	-1.7	0.8	-0.7
Systolic Blood Pressure	2.0	10.0	28.9	0.6	0.1	-2.4	-1.0	3.7	4.2	-5.4	3.0	-3.7
Smoking Status	0.3	0.7	2.8	-1.7	-0.5	0.8	-0.3	-0.8	0.3	-0.8	-0.1	1.1
Allergy or Eczema	0.3	0.9	4.5	-0.1	-0.2	-0.2	0.2	0.6	0.7	-2.1	1.5	-0.5
Cardiovascular Disease	0.3	1.2	3.5	-0.3	0.5	-0.8	-0.1	1.4	1.3	-1.9	1.1	-1.0
Hypothyroidism (self reported)	1.1	2.5	6.4	0.0	0.1	1.3	1.3	-1.4	-1.6	2.2	-2.5	1.9
Respiratory disease	0.1	0.3	1.5	0.6	-0.7	-0.6	-1.2	0.4	-0.0	0.2	-0.1	-0.0
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.5	1.2	-0.8	0.3	-1.0	-0.2	0.6	-1.1	-0.2	0.8
Lung FEV1/FVC ratio	0.5	2.4	5.3	2.2	2.3	1.5	2.1	-1.2	-0.4	-0.9	1.4	-0.7
Lung FVC	0.4	2.3	4.8	-1.5	0.8	0.8	0.1	-1.0	-1.6	2.1	-2.1	2.2
Neuroticism	0.4	0.9	2.8	-0.4	-1.5	-0.9	-1.7	0.8	1.1	-0.5	0.2	-0.1
Chronotype (morning person)	0.9	2.0	3.6	1.3	1.0	1.9	1.3	-1.8	-1.4	-0.3	-1.3	1.9
Hair Pigment	0.0	0.5	1.1	0.7	0.7	-0.1	-0.3	-0.4	-0.2	1.0	-0.9	0.9
Tanning	0.0	0.4	1.4	-1.2	0.2	0.3	-0.0	-0.1	-0.3	-0.8	1.0	-0.5
Hand grip strength (left)	1.2	3.2	7.2	2.7	2.4	1.5	1.9	-1.6	-1.6	-0.2	-1.5	1.4
Number of treatments/medications taken	0.6	1.2	3.5	-1.9	-1.3	-0.1	-0.3	0.4	0.6	-1.0	-0.3	1.9
Average weekly spirits intake	0.2	0.3	1.7	-1.3	-0.7	0.0	-0.2	-0.1	-0.1	-0.2	-0.2	-0.5
Sensitivity / hurt feelings	0.2	0.3	0.7	0.9	-0.3	-0.1	-0.8	-0.1	-0.3	0.4	-0.6	0.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.5	0.2	-0.3	-0.1	-0.7	0.2	-0.1	0.3	-1.1	1.2
Hearing difficulty/problems: Yes	1.0	1.5	5.7	-1.3	-0.5	0.1	0.0	0.4	0.6	-2.3	2.4	-0.4
Relative age of first facial hair	0.2	0.4	2.9	1.7	-0.4	-0.3	-0.0	0.2	-0.0	-0.0	-0.5	0.3
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	4.5	-1.6	-1.5	0.3	-0.3	-0.0	0.5	-1.4	1.2	2.1
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.8	-0.3	-0.9	0.8	0.6	-0.7	-0.5	0.2	-0.8	0.5
Ever had hysterectomy (womb removed)	0.4	0.5	2.7	-0.7	0.1	0.3	0.3	-0.0	0.6	-1.7	0.4	0.1
Systolic blood pressure, automated reading	0.8	2.4	5.2	0.8	0.8	-1.6	-0.2	2.0	2.2	-2.3	0.5	-1.8
Eye problems/disorders: Diabetes related eye disease	2.1	2.3	6.1	-0.9	-2.5	-1.4	-2.1	1.4	1.9	-1.1	0.2	0.2
Angina	1.0	1.3	2.4	0.3	-1.6	-1.6	-1.2	1.5	1.3	0.8	-0.0	-0.7
Medication for hormone replacement therapy	0.5	0.6	1.9	1.1	0.8	0.6	1.4	-0.6	-0.6	-0.4	0.3	-0.5
Vitamin and mineral supplements	0.8	1.0	4.3	-2.1	-0.4	0.2	-0.9	-0.2	0.3	-0.4	-0.3	2.0
Supplements: Zinc	0.1	0.1	0.6	0.2	0.3	-0.1	0.8	0.3	0.6	-0.2	-0.1	-0.2
Medication: Co-codamol	3.0	3.5	7.8	0.7	-1.8	-2.8	-2.1	2.6	2.3	-1.2	0.2	-1.4
Medication: Metformin	0.7	0.9	3.0	-0.5	0.2	1.3	0.7	-1.2	-0.4	-1.0	-0.7	1.7
Diabetes (father)	0.4	0.5	1.5	-1.0	-0.8	-0.6	-1.2	0.5	0.3	1.0	-0.1	0.0
Diabetes (mother)	0.8	1.1	3.0	0.5	0.9	0.4	0.5	-0.7	-1.5	1.7	-1.5	0.1
Severe depression (siblings)	1.1	1.2	2.9	-1.7	-1.2	-0.7	-0.4	0.8	0.8	-1.1	1.6	-0.7
Pack years adult smoking proportion	1.6	2.4	5.4	-1.6	-2.2	-0.3	-1.2	0.6	1.6	-2.3	1.3	1.7
Impedance of leg (right)	1.0	4.8	14.2	-0.6	-1.5	-1.8	-1.0	2.4	2.0	-1.9	3.0	-3.8
Leg fat-free mass (left)	0.6	3.2	7.9	0.6	2.1	1.4	0.7	-1.8	-1.3	1.2	-2.7	2.8
Trunk fat percentage	0.3	1.1	3.0	-1.7	-0.5	-0.8	-1.3	1.1	1.4	-0.5	-0.3	0.8
Hand grip strength (right)	1.4	3.9	7.4	2.7	2.6	1.8	2.3	-1.9	-2.1	0.4	-1.7	1.3
Townsend deprivation index at recruitment	1.0	1.4	3.1	-1.5	-0.4	-1.1	-1.8	1.2	1.5	-0.7	1.3	0.3
Current tobacco smoking	0.4	0.6	2.0	-1.3	-0.2	0.3	-1.2	-0.6	0.3	0.1	0.3	1.4
Average weekly fortified wine intake	0.5	0.6	2.0	0.0	-0.2	-1.2	-0.8	0.7	0.5	0.3	-0.6	-1.4
Maternal smoking around birth	0.6	0.9	3.4	0.2	1.0	0.0	0.0	-0.3	-0.8	1.7	-1.8	-0.5
Fed-up feelings	0.3	0.6	3.5	-0.5	0.1	0.3	-1.0	-0.4	-0.1	-0.2	-0.3	1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	0.6	-0.6	0.2	0.1	-0.2	-0.1	-0.5	0.5	-0.8	0.3
Relative age voice broke	0.2	0.4	1.3	0.3	0.0	-0.7	-0.6	0.4	0.3	-1.2	-0.1	-0.9
Taking other prescription medications	1.1	1.7	8.3	-1.9	-1.3	0.6	-0.3	-0.4	-0.2	0.3	-1.0	2.9
Age when periods started (menarche)	0.1	0.2	0.7	0.0	-0.5	0.3	-0.0	-0.2	0.7	-0.6	0.8	0.3
Bilateral oophorectomy (both ovaries removed)	1.2	1.3	4.8	0.4	-0.9	-0.6	-0.6	1.0	2.2	-2.0	-0.4	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.4	1.5	0.9	-0.1	0.4	0.3	-0.3	-0.4	-0.1	-0.9
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.5	-0.3	0.1	-0.2	-0.2	0.3	0.3	-0.4	0.7	0.1
Qualifications: CSEs or equivalent	1.1	1.4	3.7	1.9	1.9	-1.2	-0.6	0.7	-0.1	0.2	-0.3	-1.7
Serious illness, injury or assault to yourself	0.9	1.1	2.4	-1.0	-0.9	-0.8	-1.1	1.1	1.6	-1.5	0.4	0.0
High blood pressure	0.8	2.2	7.0	-0.7	-0.1	-1.2	-0.6	1.9	2.2	-2.7	1.0	-0.9
Hayfever, allergic rhinitis or eczema	0.3	0.7	3.1	-0.1	0.4	-0.2	-0.3	0.3	0.5	-1.8	1.5	-0.2
Multivitamins +/- minerals	0.6	0.8	3.6	1.9	0.6	-0.1	0.7	0.2	-0.1	0.5	0.3	-1.6
Stomach or abdominal pain in last month	0.4	0.5	2.3	-0.4	-0.3	-0.6	-1.5	0.3	0.0	0.6	-0.5	-0.8
Supplements: Glucosamine	0.9	1.1	3.9	0.4	1.4	-0.3	0.4	-0.2	-1.1	2.0	-1.3	-1.1
Diverticular disease/diverticulitis (self-reported)	3.1	3.6	13.4	-1.9	-3.7	-1.8	-2.3	1.8	1.5	-0.9	0.7	-0.7
Medication: Atenolol	1.3	1.6	4.2	-0.4	1.2	1.5	1.7	-1.0	-0.0	-2.0	0.3	1.6
Medication: Levothyroxine sodium	0.5	0.9	3.5	-1.2	-1.9	-0.1	-0.2	0.6	1.0	-0.2	0.1	1.2
Sitting height	0.5	3.6	9.2	0.1	3.0	1.8	1.5	-2.4	-1.7	1.7	-1.6	1.9
Chronic bronchitis/emphysema (father)	1.5	1.8	5.2	-1.4	-1.5	-1.3	-2.3	1.0	0.9	0.5	-1.7	0.5
High blood pressure (mother)	1.3	1.8	4.9	-0.2	1.4	1.5	2.2	-0.8	0.3	-2.1	1.0	0.5
Body mass index (BMI)	0.2	1.1	4.7	-0.3	0.1	0.1	-0.4	-0.2	-0.1	0.8	-1.9	2.2
Impedance of leg (left)	1.3	6.2	13.8	-0.4	-1.8	-2.0	-1.4	2.7	2.6	-2.4	3.7	-3.6
Leg predicted mass (left)	0.6	2.9	7.2	0.6	2.1	1.3	0.7	-1.7	-1.2	1.1	-2.6	2.7
Trunk fat mass	0.2	0.8	2.2	-1.2	-0.0	-0.4	-1.0	0.6	1.0	-0.4	-0.8	1.5
Waist circumference	0.2	0.8	2.6	-0.2	-0.1	-0.6	-1.1	0.7	0.9	-0.4	-1.1	1.6
Number of incorrect matches in round	3.2	5.3	8.4	-1.4	-2.5	-2.2	-2.0	2.4	2.9	-2.2	2.3	-2.6
Past tobacco smoking	0.4	0.7	3.1	1.8	0.9	-0.3	0.6	0.2	-0.4	0.6	-0.8	-0.6
Alcohol usually taken with meals	1.1	1.8	4.1	0.5	2.0	1.7	1.6	-1.6	-1.6	-0.4	0.2	0.7
Nervous feelings	0.5	0.9	4.0	-0.2	-2.0	-0.6	-0.9	0.8	1.0	-1.0	-0.1	0.2
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	3.3	-1.0	-1.8	-1.3	-1.5	1.5	1.3	-0.8	0.9	-0.4
Hearing difficulty/problems with background noise	0.9	1.5	6.7	-0.7	-0.1	-0.5	-0.8	0.8	1.1	-1.8	2.6	-0.4
Hair/balding pattern: Pattern 2	0.5	0.7	2.6	1.3	-0.5	0.2	-0.1	0.2	0.3	-1.1	1.6	-0.3
Had menopause	0.6	0.8	1.8	0.6	-1.3	-1.1	-1.3	1.0	0.5	0.7	-0.7	-0.1
Had other major operations	0.1	0.1	0.5	-0.6	0.1	0.2	-0.2	-0.2	0.3	-0.2	0.7	0.3
Forced vital capacity (FVC)	0.7	2.9	6.7	0.7	2.6	1.2	0.8	-1.7	-2.2	1.7	-2.1	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	3.4	1.8	0.2	-0.8	-0.5	1.0	0.7	-0.9	0.5	-1.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.0	0.2	-0.9	-0.1	-0.4	0.2	0.6	-1.0	0.5	0.9
Qualifications: None of the above	0.7	1.5	4.5	-1.3	-1.7	1.1	-0.1	-0.6	0.5	-0.7	1.3	2.1
Financial difficulties in last 2 years	0.5	0.7	2.0	0.4	-1.1	-0.7	-1.4	0.9	0.9	-0.9	0.2	0.6
Mouth/teeth dental problems	1.5	2.4	4.3	0.0	2.1	1.8	1.7	-1.7	-1.8	1.1	-1.9	-0.2
Heart attack	0.7	0.9	1.8	-1.2	-1.3	-0.8	-1.1	0.8	1.2	0.4	-0.7	0.8
Allergy	0.1	0.3	0.9	0.1	-0.7	0.1	0.8	0.1	0.4	0.4	-0.0	-1.0
Pain all over the body in last month	0.3	0.3	0.7	-0.9	-0.7	-0.4	-0.7	0.3	0.9	-0.1	-0.6	-0.1
Diabetes (self-reported)	0.2	0.3	1.1	-0.5	-0.2	-0.0	-1.0	-0.1	0.6	-0.8	-0.5	0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.4	-0.4	-0.3	-0.2	-0.5	0.6	0.5	-0.3	0.3	-0.5
Medication: Ramipril	1.6	2.0	3.5	0.2	1.8	1.9	1.3	-1.8	-1.6	-0.3	-1.2	1.6
Medication: Simvastatin	0.5	0.8	3.5	-0.1	-0.0	0.2	0.3	-0.4	-0.8	1.3	-1.9	1.0
Fluid intelligence score	1.0	2.1	4.2	-1.8	-1.1	-1.9	-1.5	2.0	1.2	0.6	0.1	-1.7
Illnesses of siblings	1.7	2.3	4.5	1.3	1.0	2.1	2.0	-1.8	-0.9	-2.0	0.8	1.1
Neuroticism score	0.8	1.7	4.4	0.6	-1.8	-1.5	-2.1	1.5	1.4	-0.6	0.6	-0.6
Weight	0.3	1.2	4.4	0.1	1.2	0.6	0.0	-0.7	-0.2	0.6	-2.0	2.1
Impedance of arm (right)	0.4	1.9	7.0	-1.3	-0.2	-1.5	-1.2	1.6	1.0	-0.4	0.9	-2.6
Arm fat percentage (right)	0.3	1.0	3.0	-1.3	-0.1	-0.6	-1.1	0.7	0.5	0.7	-1.7	1.3
Trunk fat-free mass	0.5	2.8	5.0	1.0	2.0	1.5	1.2	-1.8	-1.4	1.2	-2.2	2.2
Hip circumference	0.2	0.7	2.1	-0.4	1.1	0.0	-0.2	-0.1	-0.2	0.7	-1.4	1.3
Time employed in main current job	0.3	0.3	0.8	-0.8	-0.5	-0.6	-0.0	0.4	0.0	0.9	-0.8	-0.0
Alcohol intake versus 10 years previously	2.7	4.0	7.5	-1.8	-1.8	-2.0	-2.0	2.1	2.7	-1.6	2.5	-1.1
Father’s age at death	0.5	0.6	2.6	-1.6	-0.2	0.7	0.1	-0.8	-0.2	0.3	-0.0	1.4
Worrier / anxious feelings	0.3	0.6	1.0	1.0	-0.6	-0.7	-0.6	0.8	1.0	-0.4	0.7	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.7	1.3	0.5	0.0	-0.5	0.1	0.2	0.2	-0.8	0.2
Falls in the last year	0.5	0.6	1.2	0.6	0.3	-0.9	-1.0	0.7	1.0	0.7	-1.1	-0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.6	-0.8	0.2	0.4	0.4	-0.4	-0.4	0.1	0.1	0.1
Number of live births	0.9	1.2	3.0	0.3	0.7	1.7	0.8	-1.6	-1.7	0.5	-0.1	1.2
Forced expiratory volume in 1-second (FEV1)	0.8	2.6	8.4	1.5	2.9	1.5	1.4	-1.7	-1.9	0.9	-0.8	0.9
Pulse rate	0.1	0.2	0.4	-0.6	0.5	0.3	0.2	-0.6	-0.4	0.3	0.0	0.6
Happiness	0.2	0.2	0.7	-0.1	0.5	0.4	-0.1	-0.3	-0.4	0.1	-0.5	0.8
Noisy workplace	0.8	1.0	5.0	-0.5	-0.9	0.3	-0.2	-0.4	-0.6	0.8	-2.2	1.3
Qualifications: A levels/AS levels or equivalent	1.1	2.4	5.7	-0.5	-1.2	-2.1	-1.2	2.4	1.4	0.3	1.1	-2.3
Serious illness, injury or assault of a close relative in last 2 years	5.5	6.3	15.2	1.3	-1.5	-3.9	-3.4	3.6	2.7	-0.1	0.2	-2.3
Mouth/teeth dental problems: Dentures	0.6	1.1	2.9	-1.7	-1.1	-1.1	-1.3	0.9	0.7	0.3	0.3	1.1
Asthma	0.1	0.2	0.9	-0.1	-0.2	0.0	-0.9	-0.1	-0.0	-0.3	-0.1	0.7
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	5.4	-1.3	-1.3	-0.6	-0.9	0.7	1.2	-1.6	2.3	0.4
Medication: Cholesterol lowering	0.5	0.8	3.4	-0.8	-0.3	1.0	0.7	-0.9	-0.8	0.3	-0.5	1.9
Depression (self-reported)	0.8	0.9	2.4	-1.4	-0.9	-0.2	-0.9	0.8	1.0	-1.5	0.7	0.6
Medication: Lansoprazole	0.6	0.6	2.9	-0.6	-1.7	-0.2	-0.2	0.5	0.8	-1.0	0.6	-0.3
Prospective memory result	0.7	0.9	2.6	0.5	-0.1	0.3	0.5	-0.5	-0.5	1.6	-1.6	1.2
Lung cancer (father)	0.5	0.6	1.2	0.4	-0.5	-0.9	-0.9	1.1	0.6	-1.0	-0.1	-0.8
Illnesses of mother	1.3	1.5	4.7	-0.2	-2.0	-1.5	-2.2	1.4	0.7	0.3	0.4	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	9.1	1.4	3.0	1.7	1.6	-1.7	-2.1	0.8	-0.8	0.6
Pulse wave Arterial Stiffness index	1.8	2.1	10.0	-3.2	-0.3	0.7	0.3	-0.8	-1.0	1.6	-1.1	1.5
Impedance of arm (left)	0.6	3.0	9.2	-1.2	-0.7	-1.6	-1.1	1.9	1.5	-1.5	2.0	-3.0
Arm fat mass (right)	0.3	1.0	4.0	-0.8	0.7	0.2	-0.4	-0.2	-0.0	0.6	-1.9	2.0
Trunk predicted mass	0.5	2.8	5.3	0.9	2.0	1.5	1.2	-1.9	-1.4	1.1	-2.2	2.3
Standing height	0.1	1.0	5.4	0.7	2.3	1.0	0.9	-1.1	-0.3	-0.3	-0.4	0.3
Length of working week for main job	0.5	0.6	1.7	0.4	-0.7	-1.3	-0.8	1.0	0.6	0.3	-0.5	-0.9
Exposure to tobacco smoke at home	1.2	1.3	4.5	0.0	0.3	-0.3	0.2	0.9	1.1	-2.1	2.1	-0.8
Breastfed as a baby	0.6	0.7	1.9	-1.1	1.1	0.7	1.4	-0.6	-0.9	-0.4	0.4	0.3
Tense / ‘highly strung’	0.1	0.1	0.3	0.5	-0.3	0.5	0.1	0.0	0.1	-0.5	0.2	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.7	0.4	0.7	-0.1	-0.2	0.3	0.3	-0.9	-0.1	-0.5
Hair/balding pattern: Pattern 4	0.5	1.1	3.6	-1.5	-1.9	-0.8	-0.9	0.9	1.0	-0.2	0.7	-0.6
Birth weight of first child	0.2	0.4	1.2	0.7	0.1	-0.8	-0.8	0.5	0.1	0.4	0.7	-1.1
Peak expiratory flow (PEF)	2.6	6.0	12.0	1.4	2.9	3.5	3.0	-3.1	-2.7	-0.4	0.4	2.4
Pulse wave reflection index	0.9	1.1	5.2	-2.3	-1.0	0.4	0.0	-0.3	-0.4	1.1	-0.7	1.1
Ever highly irritable/argumentative for 2 days	0.8	1.0	1.8	1.0	1.0	0.8	0.6	-0.8	-1.1	0.9	-1.1	1.4
Loud music exposure frequency	0.3	0.3	0.9	-0.9	0.8	-0.3	-0.1	0.1	0.1	-0.6	0.6	-0.5
Qualifications: O levels/GCSEs or equivalent	1.1	1.7	5.8	-0.6	0.6	-1.8	-1.1	1.7	0.6	-0.2	0.9	-2.4
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.9	0.7	-1.2	-0.4	-0.4	0.5	0.8	-1.4	1.3	0.3
Blood clot in the leg (DVT)	0.1	0.1	0.3	-0.6	0.3	-0.0	0.1	-0.0	-0.3	-0.2	-0.5	0.2
Medication: Paracetamol	1.6	2.7	4.5	-2.0	-2.1	-1.3	-2.1	1.2	1.7	-1.1	2.1	0.1
Headache pain in last month	2.0	3.4	4.9	0.7	-1.9	-1.7	-1.5	2.2	2.2	-2.0	1.7	-2.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.0	1.6	-0.3	-1.5	-1.0	1.1	1.0	0.1	0.6	-1.7
Glaucoma (self-reported)	0.5	0.6	2.8	-0.5	0.3	-0.5	-0.4	0.1	0.1	1.7	-1.4	-0.4
Gout (self-reported)	1.7	2.4	4.0	-1.3	-2.0	-1.9	-1.6	1.8	1.8	0.0	1.4	-1.1
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.6	-0.1	-0.4	0.7	0.6	-0.5	-0.8	1.6	-1.6	1.5
Medication: Amlodipine	0.3	0.4	1.3	-0.4	-0.9	0.2	-0.1	0.3	1.1	-1.1	0.3	0.5
Medication: Ventolin 100micrograms inhaler	0.9	1.1	2.8	0.1	-0.8	-1.2	-1.7	1.3	0.5	0.7	-1.5	-0.7
Birth weight	0.7	1.5	5.7	-0.5	1.3	1.4	1.5	-0.9	-0.3	-2.4	0.3	1.0
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.7	0.3	0.7	0.8	0.8	-1.2	-0.9	1.3	-1.0	0.5
High blood pressure (siblings)	0.6	0.9	4.1	-0.0	0.4	-1.2	-1.0	0.9	0.1	2.0	-0.8	-0.5
Forced vital capacity (FVC), Best measure	0.5	1.8	5.5	0.7	2.3	1.2	0.8	-1.3	-1.8	0.6	-1.2	1.0
Body fat percentage	0.3	1.3	2.6	-1.4	-0.9	-1.0	-1.5	1.4	1.6	-0.4	-0.4	0.8
Leg fat percentage (right)	0.2	0.7	1.5	-0.9	-1.0	-0.8	-0.8	1.2	1.1	-0.2	-0.4	0.1
Arm fat-free mass (right)	0.4	1.9	6.3	0.6	1.4	1.4	0.8	-1.6	-0.8	0.4	-1.6	2.5
Exposure to tobacco smoke outside home	0.1	0.2	0.4	-0.4	0.7	0.4	-0.6	-0.3	0.1	-0.2	-0.2	0.5
Comparative body size at age 10	0.4	1.0	3.2	0.2	0.7	1.0	0.7	-1.0	-0.3	-1.5	-0.9	1.8
Number of full brothers	0.2	0.2	1.1	0.1	-0.0	0.3	-0.4	-0.0	0.5	-0.4	1.0	0.6
Worry too long after embarrassment	1.0	1.6	3.4	1.2	-1.8	-1.4	-1.7	1.3	1.1	-1.0	0.6	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.4	5.7	-1.3	-1.6	-1.8	-2.4	2.1	1.7	-1.1	0.2	-0.2
Wheeze or whistling in the chest in last year	0.2	0.4	1.6	1.1	1.3	-0.1	-0.4	-0.1	0.1	-0.9	-0.3	0.3
Number of children fathered	0.8	0.9	3.8	-0.2	-0.9	0.5	1.0	0.1	0.6	-1.9	1.3	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.3	-0.4	-0.7	-0.1	-0.2	0.4	0.8	-1.5	0.7	0.4
Age at first live birth	0.9	1.7	5.5	1.8	2.3	0.6	1.2	-0.9	-1.4	0.5	-0.9	-0.8
Pulse wave peak to peak time	2.0	2.4	10.7	3.3	0.4	-0.9	-0.3	1.0	1.2	-1.7	1.1	-1.7
Health satisfaction	0.5	0.6	2.0	-0.4	0.5	1.0	0.8	-0.6	0.2	-1.4	0.9	0.7
Shortness of breath walking on level ground	0.7	0.8	1.5	-0.8	-1.1	-0.6	-1.2	1.0	1.1	-0.8	0.4	0.8
Qualifications: College or University degree	0.1	0.4	1.1	0.5	1.1	-0.3	0.5	0.2	-1.0	0.7	0.3	-0.3
Eye problems/disorders: None of the above	1.0	1.2	2.5	-0.6	1.0	1.6	1.1	-1.4	-1.3	0.1	-0.7	1.3
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.6	0.5	0.3	-0.6	0.2	0.7	0.3	-0.5	0.6	-0.8
Emphysema/chronic bronchitis	0.9	1.0	4.4	-1.0	-0.1	-0.1	-0.6	-0.5	-0.5	1.1	-1.3	2.1
Medication for pain relief, constipation, heartburn	2.6	4.4	8.5	2.7	2.8	1.0	1.4	-1.4	-2.5	2.9	-2.2	-0.6
Neck or shoulder pain in last month	1.0	1.4	2.6	0.3	-1.3	-1.4	-1.6	1.4	1.2	1.4	-0.9	0.3
Medication: Blood pressure	0.8	1.4	4.9	-2.2	0.9	1.2	1.0	-0.8	-0.4	-0.7	-0.8	1.4
Angina (self-reported)	1.1	1.5	3.2	0.2	-1.8	-1.6	-1.4	1.7	1.4	0.7	-0.0	-0.8
Migraine (self-reported)	0.2	0.3	1.2	0.3	-0.1	0.1	-0.4	-0.3	-0.5	1.1	0.8	0.0
Medication: Ibuprofen	0.9	1.1	5.6	-0.9	-0.7	-0.2	-0.4	0.4	0.8	-1.3	2.4	0.4
Medication: Allopurinol	2.1	2.8	4.7	-1.0	-1.3	-2.2	-1.9	2.1	1.7	0.1	2.1	-1.5
Medication: Omeprazole	1.6	1.9	7.3	-2.7	-2.7	-0.4	-0.8	0.5	0.7	-0.5	0.6	0.6
Medication: Seretide 50 evohaler	0.7	0.8	2.7	0.1	-0.3	1.1	0.4	-0.9	0.3	-1.2	0.6	1.6
Mean time to correctly identify matches	0.7	1.4	5.8	0.9	1.9	0.2	0.4	-0.4	-0.6	1.2	-2.4	-0.3
Heart disease (mother)	1.1	1.4	2.3	-0.2	-1.2	-1.5	-1.4	1.4	1.0	1.3	-1.1	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.1	5.5	-0.2	-0.0	2.3	1.9	-1.8	-1.4	-0.6	0.5	1.9
Whole body fat mass	0.2	0.8	3.5	-0.9	-0.0	-0.2	-0.9	0.4	0.8	0.0	-1.2	1.9
Leg fat mass (right)	0.2	0.7	1.9	-0.4	-0.4	-0.5	-0.9	0.6	0.8	0.1	-1.2	1.4
Arm predicted mass (right)	0.4	1.9	6.2	0.7	1.4	1.5	0.9	-1.6	-0.8	0.4	-1.6	2.5
Pulse rate, automated reading	0.1	0.2	0.8	0.3	-0.2	-0.2	-0.3	0.1	0.9	-0.4	0.7	0.3
Alcohol intake frequency.	0.5	1.2	2.9	-0.8	-1.4	-1.3	-1.7	1.3	1.1	0.1	-0.4	-0.5
Comparative height size at age 10	0.1	0.7	3.1	0.1	-0.2	0.2	-0.4	0.2	0.9	-1.5	1.8	0.0
Number of full sisters	0.2	0.3	0.8	-0.5	-0.5	-0.4	-0.5	0.2	-0.2	0.9	0.1	-0.7
Suffer from ‘nerves’	0.8	1.3	3.6	-1.9	-0.7	-1.3	-1.6	1.3	0.5	0.2	0.0	-1.0
Overall health rating	0.2	0.5	1.2	-0.8	-0.1	-0.1	-0.8	0.3	0.8	-0.8	0.0	1.1
Chest pain or discomfort	0.4	0.6	1.2	-0.6	0.8	-0.9	-0.2	0.9	0.6	-0.8	0.5	-1.1
Had major operations	1.3	1.5	7.1	-1.2	-0.4	0.2	0.1	0.4	1.0	-2.7	1.9	-0.2
Age at last live birth	0.5	0.7	1.5	1.2	1.2	0.7	0.7	-1.0	-1.2	0.2	0.3	-0.1
Family relationship satisfaction	0.3	0.4	2.4	-0.2	1.6	0.5	-0.2	-0.5	-0.4	0.1	-0.8	0.1
Leg pain on walking	1.1	1.3	3.1	-1.8	-1.4	-1.1	-1.5	1.1	0.6	-0.4	1.4	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.4	0.6	0.7	-0.3	-0.3	-0.0	-0.2	0.4	-1.4	-1.5
Commuting to job workplace: Car/motor vehicle	0.9	1.1	3.0	0.1	-0.6	-0.8	-0.4	0.8	1.3	-1.6	0.7	-1.7
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	2.7	-1.3	0.8	1.5	1.6	-1.7	-1.6	1.0	0.0	1.2
Medication: Aspirin	1.6	2.2	5.4	0.1	-1.7	-1.4	-1.3	2.0	2.3	-1.9	0.2	-0.1
Supplements: Vitamin C	0.2	0.3	0.6	0.3	0.4	0.6	0.8	-0.7	-0.5	-0.4	0.5	-0.2
Knee pain experienced in last month	0.5	0.8	1.9	-1.3	-0.5	-1.1	-1.4	0.7	0.1	0.3	-1.1	0.1
Hypertension (Self-reported)	0.5	1.5	6.8	-0.4	0.3	-0.6	-0.1	1.3	1.9	-2.6	0.7	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	6.2	0.2	-0.4	-0.2	-0.4	0.4	0.5	-2.1	2.5	-0.2
Illnesses of father: Heart disease	1.9	2.6	4.7	-0.1	-0.3	-1.9	-1.7	2.2	2.0	-1.1	1.3	-2.2
Illnesses of siblings: Diabetes	1.0	1.3	2.3	0.8	-1.0	-1.5	-1.5	1.5	1.4	-0.1	-0.2	-1.0
Smoking status: Previous	0.2	0.2	1.4	-1.2	-0.2	0.2	0.3	-0.1	0.3	-0.4	0.6	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.7	1.3	0.9	0.2	0.3	-0.3	-0.3	-0.4	0.4	-0.5
Whole body fat-free mass	0.5	2.9	6.9	0.8	2.0	1.4	0.9	-1.8	-1.2	1.1	-2.3	2.6
Leg fat-free mass (right)	0.5	2.7	8.0	0.6	2.0	1.2	0.6	-1.7	-1.0	0.9	-2.3	2.8
Arm fat percentage (left)	0.2	0.9	1.7	-1.3	-0.5	-0.8	-1.3	0.9	0.8	0.3	-1.2	1.1
Average weekly red wine intake	1.2	1.8	4.8	0.8	2.2	1.7	1.7	-1.5	-1.3	-0.4	-0.1	0.9
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.5	0.7	-0.5	-0.3	-0.1	0.3	0.7	-0.4	-0.2	-0.2
Mood swings	0.6	1.0	4.6	0.8	-0.9	0.3	-0.7	0.2	0.9	-2.1	1.1	0.5
Loneliness, isolation	0.6	0.8	2.5	-0.7	-0.3	-0.9	-1.6	0.8	0.3	0.7	-1.3	0.1
Long-standing illness, disability or infirmity	0.7	1.1	3.0	-0.4	-1.1	-1.1	-1.7	1.2	1.2	-0.5	-0.4	1.0
Ever had bowel cancer screening	1.4	1.7	6.8	-1.3	-1.0	0.0	0.4	-0.3	-0.8	2.6	-1.9	0.8
Diabetes diagnosed by doctor	0.4	0.6	2.0	-0.1	-0.8	-0.4	-1.4	0.4	1.0	-1.2	-0.7	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.7	1.3	0.1	-0.6	-0.3	0.9	0.0	-0.2	0.8	-1.7
Friendships satisfaction	0.2	0.2	0.9	0.5	0.4	-0.4	0.3	0.6	-0.1	-0.2	0.0	-1.0
Qualifications: nursing, teaching	0.3	0.4	2.9	1.7	-0.1	-0.1	0.4	0.2	-0.3	-0.5	-0.5	-0.3
Commuting to job workplace: Walk	3.9	4.2	8.2	0.6	1.9	2.8	2.2	-2.6	-2.9	1.0	-1.2	2.0
Eye problems/disorders: Cataract	1.8	2.1	3.9	0.8	-0.9	-1.2	-0.7	1.5	1.6	-2.0	1.6	-2.0
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	3.9	1.5	0.4	-0.8	-0.4	0.3	-0.4	2.0	-0.3	-1.3
Medication for cholesterol	0.7	1.1	2.5	-1.3	-1.2	-0.9	-1.2	0.8	1.0	-0.6	1.6	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	7.8	-1.3	-2.8	-1.0	-1.0	1.3	1.3	0.1	-0.9	-0.4
Back pain experienced in last month	0.7	1.1	2.6	-0.2	-0.9	-1.1	-0.9	1.1	1.6	-1.6	0.7	-0.1
Mineral and other dietary supplements	1.3	1.8	3.1	-1.4	-1.8	-1.5	-1.7	1.3	1.3	-0.8	1.2	-0.2
Breast cancer (self-reported)	1.3	1.6	4.8	0.6	-0.2	-2.2	-1.4	1.7	1.3	-0.4	0.8	-1.4
Asthma (self-reported)	0.1	0.2	1.1	-0.2	-0.4	0.0	-1.0	-0.1	0.0	-0.4	-0.1	0.6
Osteoporosis (self-reported)	0.6	0.7	2.8	-0.9	-0.5	0.1	0.3	-0.2	-0.2	-1.7	1.5	-0.0
Osteoarthritis (self-reported)	0.6	0.7	1.7	0.4	-0.4	-1.3	-1.0	0.7	0.4	1.0	-1.3	-0.5
Medication: Aspirin	1.5	2.0	5.6	-0.4	-1.5	-1.1	-1.0	1.8	2.4	-2.1	0.3	0.1
Medication: Gliclazide	1.3	1.5	3.5	0.6	0.2	1.9	1.4	-1.5	-0.4	-1.0	0.8	1.8
Illnesses of father: None of the above (group 1)	0.4	0.4	1.1	1.1	-0.0	0.5	0.4	-0.7	-0.6	0.1	1.0	0.7
Smoking status: Current	0.4	0.7	2.3	-1.3	-0.4	0.3	-1.2	-0.6	0.4	-0.0	0.3	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	3.6	0.8	1.9	0.8	1.0	-0.8	-1.8	1.1	-0.7	0.7
Whole body water mass	0.5	2.8	6.6	0.6	2.0	1.4	0.9	-1.8	-1.2	1.0	-2.3	2.6
Leg predicted mass (right)	0.5	2.7	7.8	0.7	2.0	1.2	0.6	-1.7	-1.0	0.9	-2.3	2.8
Arm fat mass (left)	0.2	0.9	3.9	-0.9	0.3	-0.0	-0.6	0.1	0.3	0.4	-1.7	2.0
Number of self-reported non-cancer illnesses	0.4	0.7	1.5	-0.4	-1.2	-0.2	-1.0	0.5	0.6	-1.1	-0.8	0.9
Average weekly champagne plus white wine intake	0.5	0.7	2.4	-1.5	-0.5	-0.7	-0.8	0.4	-0.0	1.4	-0.5	-0.6
Miserableness	0.2	0.4	2.1	0.2	-0.0	0.5	0.2	-0.2	0.1	-1.4	0.9	0.2
Guilty feelings	0.4	0.6	2.5	0.5	-1.6	0.2	-0.7	-0.0	0.5	-1.0	-0.0	0.8
Wears glasses or contact lenses	1.6	1.9	4.3	-1.2	-2.1	-0.5	-0.4	1.0	1.4	-2.0	2.1	0.2
Ever taken oral contraceptive pill	1.9	2.1	13.1	3.6	1.5	1.1	1.0	-1.0	-0.8	-0.4	-0.1	0.4
Hearing aid user	0.3	0.3	1.4	-1.2	-0.7	0.4	0.3	-0.1	0.0	-0.2	0.9	0.3
Mother’s age at death	1.3	1.7	5.0	-2.2	0.8	1.3	1.2	-1.3	-1.3	0.6	-1.2	1.0
Financial situation satisfaction	0.6	0.8	2.3	0.8	1.2	0.7	0.7	-0.6	-0.5	-0.4	-1.5	0.9
Tinnitus: Yes, now most or all of the time	0.7	0.8	4.7	2.2	-0.5	0.3	0.2	-0.2	0.2	-1.0	0.8	0.0
Commuting to job workplace: Public transport	1.0	1.2	4.0	-2.0	-1.1	-0.8	-1.7	0.7	0.7	0.7	0.9	0.4
Eye problems/disorders: Glaucoma	0.7	0.8	3.5	0.3	0.8	-0.5	-0.5	-0.0	-0.1	1.9	-1.5	-0.1
Medication: Blood pressure	0.2	0.4	1.6	0.4	0.6	-0.1	-0.2	0.3	0.7	-1.3	-0.7	0.8
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.1	-0.9	-0.1	-0.6	-1.2	0.1	-0.5	1.8	-1.1	1.3
Supplements: Fish oil (including cod liver oil)	1.3	1.6	2.8	1.4	1.7	1.2	1.2	-1.2	-1.4	1.3	-1.5	-0.2
High cholesterol (Self-reported)	0.5	0.9	3.4	-0.4	0.4	0.4	0.2	-0.6	-1.5	1.1	-1.9	0.6
Medication: Bendroflumethiazide	0.2	0.3	0.7	-0.2	0.6	-0.4	-0.2	0.5	0.6	-0.8	-0.4	-0.5
Medication: Paracetamol	1.1	1.6	6.6	-2.6	-1.3	-0.9	-1.5	0.8	1.0	-0.2	1.3	0.3
Medication: Lisinopril	0.7	0.9	4.0	-0.6	-2.0	-0.4	-0.5	1.0	0.6	-1.0	-0.3	0.8
Medication: Atorvastatin	0.1	0.2	0.5	-0.1	-0.7	0.7	0.3	-0.3	-0.2	0.3	-0.5	0.4
Illnesses of father: High blood pressure	1.0	1.2	3.9	-0.8	0.2	-0.2	0.6	0.6	1.1	-2.0	1.8	-1.1
Alcohol drinker status: Never	1.7	2.1	7.2	-2.7	-2.5	-1.3	-0.9	1.3	0.9	0.1	-0.1	0.2
Ever smoked	0.6	1.0	4.5	-2.1	-1.1	0.4	-1.1	-0.2	0.5	-0.9	0.4	1.0
Basal metabolic rate	0.5	2.7	7.2	0.6	2.0	1.4	0.8	-1.7	-1.1	1.1	-2.3	2.7
Leg fat percentage (left)	0.2	0.7	1.7	-0.4	-1.0	-0.8	-1.0	1.2	1.3	-0.3	-0.3	0.4
Arm fat-free mass (left)	0.4	2.2	6.2	0.7	1.7	1.3	0.9	-1.5	-0.9	1.0	-1.9	2.5
Number of operations (self-reported)	2.5	3.7	12.9	0.2	-1.4	-1.3	-1.3	1.9	2.6	-3.6	1.9	-0.9
Average weekly beer plus cider intake	2.0	2.9	6.2	0.5	-1.4	-2.5	-1.7	2.1	1.9	-0.4	0.7	-2.5
Irritability	0.3	0.6	1.6	0.5	-1.1	-0.8	-1.3	0.8	0.7	0.5	0.2	-0.1
Risk taking	0.4	0.6	1.2	0.5	-0.5	-1.1	-0.9	1.0	1.0	-0.6	-0.5	-0.7
Ever had prostate specific antigen (PSA) test	1.1	1.2	7.2	-2.7	-0.6	0.8	1.1	-0.7	-0.5	0.6	-0.7	0.5
Fractured/broken bones in last 5 years	0.8	1.0	3.3	1.8	1.2	0.4	0.5	-0.6	-0.4	0.5	-1.6	0.6
Age started oral contraceptive pill	1.0	1.3	3.5	-1.0	-1.9	-1.1	-1.2	1.1	1.2	-1.1	0.6	0.2
Diastolic blood pressure, automated reading	0.5	1.6	4.1	0.7	1.2	-0.9	0.1	1.3	1.8	-2.0	1.1	-1.3
Ever depressed for a whole week	0.3	0.3	1.5	-0.3	0.2	0.1	0.1	0.2	0.3	-1.2	1.0	0.1
Unable to work because of sickness or disability	1.6	2.1	3.8	-0.9	-1.7	-1.6	-1.9	1.7	1.7	-0.6	0.7	-1.4
Commuting to job workplace: Cycle	0.4	0.5	2.0	0.8	0.8	0.0	0.8	0.3	-0.8	1.4	-0.3	-0.4
Myopia	2.0	2.9	5.4	-0.6	1.8	1.8	1.4	-2.2	-2.3	1.9	-1.5	1.3
Vascular/heart problems diagnosed by doctor	0.4	1.2	4.0	0.6	0.0	0.9	0.3	-1.5	-1.7	2.0	-0.3	0.3
Cholesterol lowering medication	0.8	1.2	4.8	1.4	-0.8	-0.3	-0.5	0.3	0.0	1.4	-2.2	0.7
Medication: Omeprazole (e.g. Zanprol)	2.1	2.5	10.7	-2.7	-3.3	-0.7	-1.2	0.8	1.1	-0.6	0.2	0.5
Pain experienced in last month	0.4	0.7	1.6	0.8	0.6	0.6	1.3	-0.5	-1.2	1.0	0.1	-0.7
Supplements: Calcium	0.2	0.2	0.6	0.0	-0.7	-0.2	-0.1	0.2	0.5	-0.7	0.8	0.0
Basal cell carcinoma (self-reported)	0.6	0.7	2.7	-1.6	-1.4	-0.1	0.2	0.0	-0.4	0.6	-0.8	0.9
Heart attack/myocardial infarction (self-reported)	0.8	1.0	2.3	-1.1	-1.5	-0.8	-1.1	0.8	1.2	0.5	-0.7	0.9
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.3	-0.3	0.5	-0.2	-0.0	0.0	-0.2	-0.1	-0.5	-0.1
Heart disease (siblings)	0.2	0.2	1.2	0.0	-0.2	-0.1	-0.2	0.1	-0.5	1.1	-0.7	-0.2
Alcohol drinker status: Previous	1.3	1.5	3.9	0.8	-1.2	-1.5	-2.0	1.6	1.2	0.0	0.1	-1.2
Pack years of smoking	1.6	2.3	5.0	-1.7	-2.2	-0.3	-1.1	0.6	1.6	-2.2	1.2	1.7
Impedance of whole body	0.9	4.8	12.7	-1.1	-1.2	-1.9	-1.3	2.4	2.2	-1.9	2.9	-3.6
Leg fat mass (left)	0.2	0.7	2.2	-0.1	-0.3	-0.4	-1.0	0.6	0.9	-0.0	-1.1	1.5
Arm predicted mass (left)	0.5	2.7	6.8	0.5	2.0	1.5	1.1	-1.8	-1.1	1.0	-2.0	2.6